Nicolae Simionescu
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Romanian physician
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Philosophy
Nicolae Simionescu's Degrees
- Doctorate Medicine University of Bucharest
Why Is Nicolae Simionescu Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nicolae Simionescu was a Romanian physician. Born in Bucharest, he attended Dimitrie Cantemir and then Saint Andrew High School, graduating in 1944. He then enrolled in the medical faculty of the University of Bucharest, which he completed in 1950, earning his doctorate in 1966. From 1946 to 1970, he was on the staff of the same institution, rising from junior teaching assistant to teaching assistant to associate professor and department chairman. Meanwhile, he improved his skills as a surgeon until 1957, when he transferred to the Bucharest Endocrinology Institute. Working there until 1970, he conducted experimental and clinical research, functioning as head researcher in the morphology section. Relocating to the United States in 1970 with permission from the communist party, he worked under George Emil Palade, first at The Rockefeller University and then at Yale University .
Nicolae Simionescu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Cardiovascular System (1983) (3428)
- Galloylglucoses of low molecular weight as mordant in electron microscopy. I. Procedure, and evidence for mordanting effect (1976) (594)
- Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels (1975) (531)
- Segmental differentiations of cell junctions in the vascular endothelium. The microvasculature (1975) (432)
- Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis (1986) (363)
- Visualization of the binding, endocytosis, and transcytosis of low- density lipoprotein in the arterial endothelium in situ (1983) (343)
- Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins (1976) (306)
- MORPHOMETRIC DATA ON THE ENDOTHELIUM OF BLOOD CAPILLARIES (1974) (290)
- Prelesional events in atherogenesis. Accumulation of extracellular cholesterol-rich liposomes in the arterial intima and cardiac valves of the hyperlipidemic rabbit. (1986) (284)
- Cellular aspects of transcapillary exchange. (1983) (271)
- Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential distribution of anionic sites (1981) (263)
- PERMEABILITY OF INTESTINAL CAPILLARIES : Pathway followed by Dextrans and Glycogens (1972) (257)
- Structural aspects of the permeability of the microvascular endothelium. (1979) (246)
- Differentiated microdomains on the luminal surface of the capillary endothelium. II. Partial characterization of their anionic sites (1981) (232)
- PERMEABILITY OF MUSCLE CAPILLARIES TO EXOGENOUS MYOGLOBIN (1973) (194)
- Open junctions in the endothelium of the postcapillary venules of the diaphragm (1978) (179)
- Structural basis of permeability in sequential segments of the microvasculature of the diaphragm. II. Pathways followed by microperoxidase across the endothelium. (1978) (173)
- Differentiated microdomains on the luminal surface of capillary endothelium: distribution of lectin receptors (1982) (156)
- Histamine receptors of the microvascular endothelium revealed in situ with a histamine-ferritin conjugate: characteristic high-affinity binding sites in venules (1982) (151)
- Endothelial transport of macromolecules: transcytosis and endocytosis. A look from cell biology. (1991) (148)
- Preferential distribution of anionic sites on the basement membrane and the abluminal aspect of the endothelium in fenestrated capillaries (1982) (122)
- Endothelial Cell Biology in Health and Disease (1988) (120)
- Identification of albumin-binding proteins in capillary endothelial cells (1988) (111)
- Functions of the endothelial cell surface. (1986) (103)
- Prelesional events in atherogenesis. Colocalization of apolipoprotein B, unesterified cholesterol and extracellular phospholipid liposomes in the aorta of hyperlipidemic rabbit. (1987) (102)
- Organization of cell junctions in the peritoneal mesothelium (1977) (100)
- Rings of membrane sterols surround the openings of vesicles and fenestrae, in capillary endothelium (1983) (94)
- Galloylglucoses of low molecular weight as mordant in electron microscopy. II. The moiety and functional groups possibly involved in the mordanting effect (1976) (93)
- Differentiated microdomains on the luminal surface of the capillary endothelium. (1981) (89)
- Endothelial albumin binding proteins are membrane-associated components exposed on the cell surface. (1989) (84)
- Development of intracellular lipid deposits in the lipid-laden cells of atherosclerotic lesions. A cytochemical and ultrastructural study. (1987) (84)
- Proatherosclerotic events: pathobiochemical changes occurring in the arterial wall before monocyte migration (1993) (77)
- DEXTRANS AND GLYCOGENS AS PARTICULATE TRACERS FOR STUDYING CAPILLARY PERMEABILITY (1971) (76)
- Endothelial Cell Dysfunctions (1992) (74)
- Isolation and characterization of endothelial cells from the heart microvasculature. (1978) (69)
- BIOCHEMICALLY DIFFERENTIATED MICRODOMAINS OF THE CELL SURFACE OF CAPILLARY ENDOTHELIUM * (1982) (66)
- Anionized and cationized hemeundecapeptides as probes for cell surface charge and permeability studies: differentiated labeling of endothelial plasmalemmal vesicles (1985) (64)
- Structural basis of permeability in sequential segments of the microvasculature of the diaphragm. I. Bipolar microvascular fields. (1978) (64)
- Pathobiochemistry of combined diabetes and atherosclerosis studied on a novel animal model. The hyperlipemic-hyperglycemic hamster. (1996) (59)
- Transcytosis and Traffic of Membranes in the Endothelial Cell (1981) (56)
- Albumin-binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells. (1993) (56)
- In vitro formation of oxidatively-modified and reassembled human low-density lipoproteins: antioxidant effect of albumin. (1993) (55)
- Binding and transcytosis of glycoalbumin by the microvascular endothelium of the murine myocardium: evidence that glycoalbumin behaves as a bifunctional ligand (1988) (50)
- Differentiated microdomains of the luminal plasmalemma of murine muscle capillaries: segmental variations in young and old animals (1985) (49)
- Intimal thickenings of human aorta contain modified reassembled lipoproteins. (1995) (48)
- RECENT STUDIES ON VASCULAR ENDOTHELIUM (1976) (47)
- Partial chemical characterization of the anionic sites in the basal lamina of fenestrated capillaries. (1984) (46)
- Ultrastructural evidence of differential solubility in Triton X-100 of endothelial vesicles and plasma membrane. (1995) (45)
- Prelesional Modifications of the Vessel Wall in Hyperlipidemic Atherogenesis (1990) (44)
- How Plasma Macromolecules Cross the Endothelium (1987) (44)
- The cerebral microvasculature of the rat: structure and luminal surface properties during early development. (1988) (42)
- Experimental obstructive coronary atherosclerosis in the hyperlipidemic hamster. (1990) (37)
- Enzymatic tracers in the study of vascular permeability. (1979) (36)
- ENDOTHELIAL CELL RECEPTORS FOR HISTAMINE * (1982) (33)
- Cellular interactions of lipoproteins with the vascular endothelium: endocytosis and transcytosis. (1991) (32)
- Transport pathways of beta-VLDL by aortic endothelium of normal and hypercholesterolemic rabbits. (1989) (32)
- Increased adhesion of human diabetic platelets to cultured valvular endothelial cells. (1992) (31)
- Structural-functional correlates in the transendothelial exchange of water-soluble macromolecules. (1976) (31)
- PERMEABILITY OF INTESTINAL CAPILLARIES (1972) (30)
- Interactions of endogenous lipoproteins with capillary endothelium in spontaneously hyperlipoproteinemic rats. (1985) (26)
- Differentiated uptake and transcytosis of albumin in successive vascular segments. (1988) (25)
- Cytochemical localization of beta-lipoproteins and their components in successive stages of hyperlipidemic atherogenesis of rabbit aorta. (1989) (25)
- Cardiomyocytes express albumin binding proteins. (1992) (24)
- Heart microvessels and aortic endothelial cells express the 15 kDa heart-type fatty acid-binding proteins. (1998) (23)
- Purification and partial characterization of extracellular liposomes isolated from the hyperlipidemic rabbit aorta. (1990) (22)
- Changes in the organization of membrane lipids during human platelet activation. Study by fluorescent and freeze-fracture cytochemistry. (1986) (21)
- Characteristic endothelial junctions in different segments of the vascular system. (1976) (20)
- Prelesional Changes of Arterial Endothelium in Hyperlipoproteinemic Atherogenesis (1988) (18)
- Prelesional events in atherogenesis. Changes induced by hypercholesterolemia in the cell surface chemistry of arterial endothelium and blood monocytes, in rabbit. (1987) (18)
- Pathobiochemical changes of the arterial wall at the inception of atherosclerosis. (1993) (18)
- Binding of vascular anticoagulant alpha (annexin V) to the aortic intima of the hypercholesterolemic rabbit. An autoradiographic study (1994) (14)
- The effect of ACE inhibitors on atheroma formation is potentiated by association with a calcium channel blocker. A biochemical and ultrastructural study. (1997) (13)
- Intrinsic procoagulant surface induced by hypercholesterolaemia on rabbit aortic endothelium. (1993) (13)
- Micro vascular endothelium segmental differentiations transcytosis and selective distribution of anionic sites (1979) (13)
- 4‐Hydroxynonenal induces membrane perturbations and inhibition of basal prostacyclin production in endothelial cells, and migration of monocytes. (1994) (11)
- Further evidence for the distribution and nature of histamine receptors on microvascular endothelium. (1986) (11)
- Experimental evaluation of the vascular effects and transport of an iodinated macromolecular contrast medium. (1997) (8)
- Opening Address: Differentiated Microdomains in the Vascular Endothelium (1982) (8)
- Endothelial cell plasma membrane obtained by chemically induced vesiculation. (1987) (8)
- Cell surface chemistry of arterial endothelium and blood monocytes in the normolipidemic rabbit. (1987) (8)
- Detection of histamine receptors at cellular level. (1984) (8)
- Endothelial Cell Dysfunction and Injury in Experimental Hyperlipidemic Atherogenesis (1992) (7)
- In vitro study of low density lipoprotein--collagen interaction. (1984) (6)
- Expression of transferrin receptors in endothelial cells transfected by electroporation. (1997) (6)
- Differential effect of two calcium channel blockers--nifedipine and diltiazem--on atherogenesis in hypercholesterolemic hamster. (1996) (5)
- Some Major Plasmalemma Proteins of Human Diabetic Platelets are Involved in the Enhanced Platelet Adhesion to Cultured Valvular Endothelial Cells. (1993) (5)
- A method for selective radiolabeling of lung endothelium plasmalemmal vesicles, in situ. (1994) (3)
- The permeability of aortic endothelium to 125I-BSA in hyperlipidemic hamster. Effect of histamine and serotonin. (1986) (3)
- The hyperlipidemic and diabetic hamster, a novel animal model (1994) (3)
- Albumin binding sites are expressed on the abluminal plasma membrane of capillary endothelium. (1991) (3)
- Receptor-mediated transcytosis of albumin by endothelial cells (1990) (2)
- Endothelial Specific Binding Sites for Permeant Plasma Macromolecules: Albumin Binding Proteins (1989) (2)
- High and low molecular weight tracers for the electron microscopical detection of sialoglycoconjugates (1987) (2)
- Ultrastructural investigation of the vascular transport of an iodinated macromolecular contrast medium. (1996) (1)
- Localization of galactose-specific lectins in human platelet plasmalemma☆ (1990) (1)
- Study of the endogenous lectins of the human platelet plasma membrane. (1986) (1)
- SPECIFIC BINDING OF ALBUMIN TO CULTURED AORTIC ENDOTHELIUM (1992) (1)
- Neonatal cardiomyocytes express albumin binding proteins (1990) (0)
- Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids (2003) (0)
- How Plccsma Macromolecules the Endothelium (1987) (0)
- Enhanced uptake and transcytosis of ?-VLDL by hyperlipidemic rabbit endothelium (1990) (0)
- Expression of procoagulant, anionic phospholipid rich endothelial surface during experimental hypercholesterolemia (1990) (0)
- Endothelial transport of macromolecules: transcytosis and endocytosis. A look from cell biology. (1991) (0)
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