Nigel Scrutton
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Professor of Chemistry at the University of Manchester
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Chemistry
Why Is Nigel Scrutton Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nigel Shaun Scrutton is a British biochemist and biotechnology innovator known for his work on enzyme catalysis, biophysics and synthetic biology. He is Director of the UK Future Biomanufacturing Research Hub, Director of the Fine and Speciality Chemicals Synthetic Biology Research Centre , and Co-founder, Director and Chief Scientific Officer of the 'fuels-from-biology' company C3 Biotechnologies Ltd. He is Professor of Enzymology and Biophysical Chemistry in the Department of Chemistry at the University of Manchester. He is former Director of the Manchester Institute of Biotechnology .
Nigel Scrutton's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Redesign of the coenzyme specificity of a dehydrogenase by protein engineering (1990) (668)
- Atomic Description of an Enzyme Reaction Dominated by Proton Tunneling (2006) (269)
- Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades (2015) (264)
- Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases (2010) (255)
- Good vibrations in enzyme-catalysed reactions. (2012) (232)
- Covalent attachment of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) to enzymes: The current state of affairs (1998) (197)
- Cation-pi bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands. (1996) (191)
- Enzymatic H-transfer requires vibration-driven extreme tunneling. (1999) (177)
- Biotransformation of Explosives by the Old Yellow Enzyme Family of Flavoproteins (2004) (167)
- New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition (2015) (161)
- UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis (2015) (149)
- Building a global alliance of biofoundries (2019) (144)
- Discovery, Characterisation, Engineering and Applications of Ene Reductases for Industrial Biocatalysis. (2018) (139)
- What’s in a covalent bond? (2009) (132)
- Biodiversity of cytochrome P450 redox systems. (2005) (130)
- An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals (2018) (127)
- Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes (2016) (121)
- New developments in 'ene'-reductase catalysed biological hydrogenations. (2014) (115)
- Dynamics driving function − new insights from electron transferring flavoproteins and partner complexes (2007) (112)
- Electron Transfer Partners of Cytochrome P450 (2005) (112)
- The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase (2005) (112)
- A new conceptual framework for enzyme catalysis. Hydrogen tunnelling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes. (2002) (108)
- Structural basis of kynurenine 3-monooxygenase inhibition (2013) (107)
- Extensive conformational sampling in a ternary electron transfer complex (2003) (103)
- Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation. (2009) (103)
- Biocatalysis with Thermostable Enzymes: Structure and Properties of a Thermophilic ‘ene’‐Reductase related to Old Yellow Enzyme (2010) (101)
- Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme. (2001) (99)
- Creation of an NADP-dependent pyruvate dehydrogenase multienzyme complex by protein engineering. (1993) (97)
- Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis (2017) (96)
- Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase (2013) (93)
- Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects (2007) (92)
- H-tunneling in the Multiple H-transfers of the Catalytic Cycle of Morphinone Reductase and in the Reductive Half-reaction of the Homologous Pentaerythritol Tetranitrate Reductase* (2003) (89)
- Chemical aspects of amine oxidation by flavoprotein enzymes. (2004) (87)
- Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme. (2005) (84)
- Extensive Domain Motion and Electron Transfer in the Human Electron Transferring Flavoprotein·Medium Chain Acyl-CoA Dehydrogenase Complex* (2004) (83)
- Fast protein motions are coupled to enzyme H-transfer reactions. (2013) (83)
- Kinetic and Structural Basis of Reactivity of Pentaerythritol Tetranitrate Reductase with NADPH, 2-Cyclohexenone, Nitroesters, and Nitroaromatic Explosives* (2002) (82)
- The Human Apoptosis-inducing Protein AMID Is an Oxidoreductase with a Modified Flavin Cofactor and DNA Binding Activity* (2005) (82)
- Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of alpha,beta-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase. (2008) (79)
- Relaxation kinetics of cytochrome P450 reductase: internal electron transfer is limited by conformational change and regulated by coenzyme binding. (2002) (79)
- The photochemical mechanism of a B12-dependent photoreceptor protein (2015) (79)
- Kinetic studies of the mechanism of carbon-hydrogen bond breakage by the heterotetrameric sarcosine oxidase of Arthrobacter sp. 1-IN. (2000) (79)
- Updated structure of Drosophila cryptochrome (2013) (77)
- Importance of Barrier Shape in Enzyme-catalyzed Reactions (2001) (76)
- Towards synthesis of monoterpenes and derivatives using synthetic biology. (2016) (76)
- Quantum Tunnelling in Enzyme-Catalysed Reactions (2009) (76)
- Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions. (2010) (76)
- Nuclear Quantum Tunneling in the Light-activated Enzyme Protochlorophyllide Oxidoreductase* (2009) (75)
- Crystal Structure of Bacterial Morphinone Reductase and Properties of the C191A Mutant Enzyme* (2002) (74)
- Channelling and formation of ‘active’ formaldehyde in dimethylglycine oxidase (2003) (74)
- Stopped-flow kinetic studies of flavin reduction in human cytochrome P450 reductase and its component domains. (2001) (73)
- New insights into enzyme catalysis. Ground state tunnelling driven by protein dynamics. (1999) (71)
- Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction. (2009) (70)
- Electron transfer in human cytochrome P450 reductase. (2001) (69)
- Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase. (2008) (68)
- Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli. (2019) (66)
- Catalytic mechanism of cofactor-free dioxygenases and how they circumvent spin-forbidden oxygenation of their substrates. (2015) (66)
- Vertebrate Cryptochromes are Vestigial Flavoproteins (2017) (65)
- Alpha-secondary isotope effects as probes of "tunneling-ready" configurations in enzymatic H-tunneling: insight from environmentally coupled tunneling models. (2006) (64)
- Crystal Structure of a Soluble Form of Human CD73 with Ecto‐5′‐Nucleotidase Activity (2012) (63)
- Deuterium Isotope Effects during Carbon–Hydrogen Bond Cleavage by Trimethylamine Dehydrogenase (2001) (63)
- Switching kinetic mechanism and putative proton donor by directed mutagenesis of glutathione reductase. (1989) (62)
- Rapid P450 Heme Iron Reduction by Laser Photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1 (2007) (60)
- Proton-coupled electron transfer in the catalytic cycle of Alcaligenes xylosoxidans copper-dependent nitrite reductase. (2011) (60)
- A microbial platform for renewable propane synthesis based on a fermentative butanol pathway (2015) (59)
- Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering (2019) (59)
- Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli. (2015) (59)
- A living foundry for Synthetic Biological Materials: A synthetic biology roadmap to new advanced materials (2018) (59)
- Cryptochrome-dependent magnetic field effect on seizure response in Drosophila larvae (2014) (59)
- Electrical circuitry in biology: emerging principles from protein structure. (2004) (58)
- A Site‐Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity (2011) (58)
- Nature of the energy landscape for gated electron transfer in a dynamic redox protein. (2010) (58)
- Switching Pyridine Nucleotide Specificity in P450 BM3 (2005) (58)
- Organization of the genes involved in dimethylglycine and sarcosine degradation in Arthrobacter spp.: implications for glycine betaine catabolism. (2001) (57)
- Reductive and oxidative half-reactions of glutathione reductase from Escherichia coli. (1994) (57)
- Selenzyme: enzyme selection tool for pathway design (2017) (57)
- Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis (2019) (56)
- Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems (2006) (56)
- Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues. (2003) (55)
- Anatomy of an engineered NAD‐binding site (1994) (55)
- Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum (2013) (55)
- Proton tunneling in aromatic amine dehydrogenase is driven by a short-range sub-picosecond promoting vibration: consistency of simulation and theory with experiment. (2007) (55)
- Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding (2016) (55)
- Sweating the assets of flavin cofactors: new insight of chemical versatility from knowledge of structure and mechanism. (2016) (54)
- Stopped-flow kinetic studies of electron transfer in the reductase domain of neuronal nitric oxide synthase: re-evaluation of the kinetic mechanism reveals new enzyme intermediates and variation with cytochrome P450 reductase. (2002) (54)
- Are the Catalytic Properties of Enzymes from Piezophilic Organisms Pressure Adapted? (2009) (53)
- The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme–substrate complex (2008) (52)
- Quantum Biology: An Update and Perspective (2021) (52)
- Proton-coupled electron transfer and adduct configuration are important for C4a-hydroperoxyflavin formation and stabilization in a flavoenzyme. (2014) (51)
- Barrier compression enhances an enzymatic hydrogen-transfer reaction. (2009) (50)
- Conformational and thermodynamic control of electron transfer in neuronal nitric oxide synthase. (2007) (50)
- Magnetic field effect studies indicate reduced geminate recombination of the radical pair in substrate-bound adenosylcobalamin-dependent ethanolamine ammonia lyase. (2007) (50)
- Purification and characterization of glutathione reductase encoded by a cloned and over-expressed gene in Escherichia coli. (1987) (49)
- Coupled Motions Direct Electrons along Human Microsomal P450 Chains (2011) (48)
- Enzymology takes a quantum leap forward (2000) (48)
- Photochemical Mechanism of Light-Driven Fatty Acid Photodecarboxylase (2020) (48)
- Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site‐Saturated Libraries (2010) (47)
- Tunneling and classical paths for proton transfer in an enzyme reaction dominated by tunneling: oxidation of tryptamine by aromatic amine dehydrogenase. (2007) (47)
- Hydrogen tunneling in quinoproteins. (2004) (47)
- Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms. (2007) (47)
- QM/MM studies show substantial tunneling for the hydrogen-transfer reaction in methylamine dehydrogenase. (2001) (46)
- NADPH generation in Aspergillus nidulans: is the mannitol cycle involved? (1988) (46)
- Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1. (2003) (45)
- Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains. (2003) (45)
- Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase (2010) (44)
- Lys300 plays a major role in the catalytic mechanism of maize polyamine oxidase. (2005) (44)
- Continuous wave photolysis magnetic field effect investigations with free and protein-bound alkylcobalamins. (2009) (44)
- Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. (2004) (44)
- Cooperativity induced by a single mutation at the subunit interface of a dimeric enzyme: glutathione reductase. (1992) (44)
- Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction. (1991) (44)
- Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase. (2003) (44)
- Atomic Resolution Structures and Solution Behavior of Enzyme-Substrate Complexes of Enterobacter cloacae PB2 Pentaerythritol Tetranitrate Reductase (2004) (43)
- Structural and biochemical characterization of recombinant wild type and a C30A mutant of trimethylamine dehydrogenase from methylophilus methylotrophus (sp. W(3)A(1)). (1999) (43)
- A Stable Tyrosyl Radical in Monoamine Oxidase A* (2005) (43)
- Enzyme catalysis: over-the-barrier or through-the-barrier? (2000) (43)
- Barrier compression and its contribution to both classical and quantum mechanical aspects of enzyme catalysis. (2010) (42)
- Inter‐flavin electron transfer in cytochrome P450 reductase – effects of solvent and pH identify hidden complexity in mechanism (2008) (42)
- Alternative proton donors/acceptors in the catalytic mechanism of the glutathione reductase of Escherichia coli: the role of histidine-439 and tyrosine-99. (1989) (42)
- Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases. (2000) (41)
- Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins (2011) (41)
- Magnetic Fields Modulate Blue-Light-Dependent Regulation of Neuronal Firing by Cryptochrome (2016) (41)
- On the role and formation of covalently bound flavin cofactors (2009) (41)
- Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase (2017) (40)
- Low carbon strategies for sustainable bio-alkane gas production and renewable energy (2020) (40)
- Protein interactions in the human methionine synthase-methionine synthase reductase complex and implications for the mechanism of enzyme reactivation. (2007) (40)
- Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA. (2003) (40)
- Demonstration of Proton-coupled Electron Transfer in the Copper-containing Nitrite Reductases* (2009) (40)
- Excited state dynamics and catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase. (2012) (39)
- Ultrafast infrared spectral fingerprints of vitamin B12 and related cobalamins. (2012) (39)
- Flavocytochrome P450 BM3 and the origin of CYP102 fusion species. (2006) (39)
- Trimethylamine dehydrogenase of bacterium W3A1 Molecular cloning, sequence determination and over‐expression of the gene (1992) (38)
- Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering (2019) (38)
- Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry. (2007) (38)
- Large-scale domain conformational change is coupled to the activation of the Co-C bond in the B12-dependent enzyme ornithine 4,5-aminomutase: a computational study. (2012) (38)
- Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase** (2014) (38)
- Incorporation of hydrostatic pressure into models of hydrogen tunneling highlights a role for pressure-modulated promoting vibrations. (2008) (37)
- Enzyme-Catalyzed Electron and Radical Transfer (2000) (37)
- Assembly of redox centers in the trimethylamine dehydrogenase of bacterium W3A1. Properties of the wild-type enzyme and a C30A mutant expressed from a cloned gene in Escherichia coli. (1994) (37)
- Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis. (1998) (37)
- Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands. (2001) (37)
- A ‘Plug and Play’ Platform for the Production of Diverse Monoterpene Hydrocarbon Scaffolds in Escherichia coli (2016) (36)
- Donor-Acceptor Distance Sampling Enhances the Performance of "Better than Nature" Nicotinamide Coenzyme Biomimetics. (2016) (36)
- The primary structure of Hyphomicrobium X dimethylamine dehydrogenase. Relationship to trimethylamine dehydrogenase and implications for substrate recognition. (1995) (36)
- Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes. (2015) (35)
- Conformational events during ternary enzyme-substrate complex formation are rate limiting in the catalytic cycle of the light-driven enzyme protochlorophyllide oxidoreductase. (2008) (35)
- Cryogenic and Laser Photoexcitation Studies Identify Multiple Roles for Active Site Residues in the Light-driven Enzyme Protochlorophyllide Oxidoreductase* (2009) (35)
- Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers† †Electronic supplementary information (ESI) available: Additional experimental sections, tables, figures and discussion. See DOI: 10.1039/c5cy01642h Click here (2015) (35)
- Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex (2009) (35)
- Involvement of a flavin iminoquinone methide in the formation of 6-hydroxyflavin mononucleotide in trimethylamine dehydrogenase: a rationale for the existence of 8alpha-methyl and C6-linked covalent flavoproteins. (1997) (34)
- Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper‐dependent nitrite reductase (2012) (34)
- Catalytic mechanism of hydride transfer between NADP+/H and ferredoxin-NADP+ reductase from Anabaena PCC 7119. (2007) (34)
- Alternative Hydride Sources for Ene‐Reductases: Current Trends (2014) (34)
- The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease (2013) (34)
- DNA Binding Suppresses Human AIF-M2 Activity and Provides a Connection between Redox Chemistry, Reactive Oxygen Species, and Apoptosis* (2007) (34)
- Engineering of an intersubunit disulphide bridge in glutathione reductase from Escherichia coli (1988) (33)
- α/β Barrel evolution and the modular assembly of enzymes: Emerging trends in the flavin oxidase/dehydrogenase family (1994) (33)
- Optimizing the Michaelis Complex of Trimethylamine Dehydrogenase (2001) (33)
- Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein* (2005) (33)
- Impact of residues remote from the catalytic centre on enzyme catalysis of copper nitrite reductase (2014) (33)
- Electron transfer from flavin to iron in the Pseudomonas oleovorans rubredoxin reductase-rubredoxin electron transfer complex. (1998) (33)
- Protein Dynamics Enhance Electronic Coupling in Electron Transfer Complexes* (2001) (32)
- Analysis of classical and quantum paths for deprotonation of methylamine by methylamine dehydrogenase. (2007) (32)
- Biocatalytic Routes to Lactone Monomers for Polymer Production. (2018) (32)
- Is there a dynamic protein contribution to the substrate trigger in coenzyme B12-dependent ethanolamine ammonia lyase? (2011) (32)
- Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis. (2003) (31)
- Radical-based photoinactivation of fatty acid photodecarboxylases. (2020) (31)
- Stepwise Hydride Transfer in a Biological System: Insights into the Reaction Mechanism of the Light‐Dependent Protochlorophyllide Oxidoreductase (2018) (31)
- biochem4j: Integrated and extensible biochemical knowledge through graph databases (2017) (30)
- Techno-economic assessment of microbial limonene production (2019) (30)
- Mutagenesis Alters the Catalytic Mechanism of the Light-driven Enzyme Protochlorophyllide Oxidoreductase* (2009) (30)
- Altering kinetic mechanism and enzyme stability by mutagenesis of the dimer interface of glutathione reductase. (1995) (30)
- αArg-237 in Methylophilus methylotrophus (sp. W3A1) Electron-transferring Flavoprotein Affords ∼200-Millivolt Stabilization of the FAD Anionic Semiquinone and a Kinetic Block on Full Reduction to the Dihydroquinone* (2001) (30)
- Mechanism of Radical-based Catalysis in the Reaction Catalyzed by Adenosylcobalamin-dependent Ornithine 4,5-Aminomutase* (2008) (30)
- Proton transfer in the oxidative half‐reaction of pentaerythritol tetranitrate reductase (2005) (30)
- Relating localized protein motions to the reaction coordinate in coenzyme B12‐dependent enzymes (2013) (29)
- How does pressure affect barrier compression and isotope effects in an enzymatic hydrogen tunneling reaction? (2011) (29)
- Human Cryptochrome-1 Confers Light Independent Biological Activity in Transgenic Drosophila Correlated with Flavin Radical Stability (2012) (29)
- SelProm: A Queryable and Predictive Expression Vector Selection Tool for Escherichia coli. (2019) (29)
- The Reaction of Trimethylamine Dehydrogenase with Trimethylamine* (1999) (29)
- Protein motions are coupled to the reaction chemistry in coenzyme B12-dependent ethanolamine ammonia lyase. (2012) (29)
- New enzymes for old: Redesigning the coenzyme and substrate specificities of glutathione reductase (1991) (29)
- Are environmentally coupled enzymatic hydrogen tunneling reactions influenced by changes in solution viscosity? (2008) (29)
- Structure-based Mechanism of CMP-2-keto-3-deoxymanno-octulonic Acid Synthetase (2009) (29)
- Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers (2020) (29)
- Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate (2020) (29)
- Role of Active Site Residues and Solvent in Proton Transfer and the Modulation of Flavin Reduction Potential in Bacterial Morphinone Reductase* (2005) (28)
- Magnetic field effects and radical pair mechanisms in enzymes: a reappraisal of the horseradish peroxidase system. (2006) (28)
- Electron transfer in human methionine synthase reductase studied by stopped-flow spectrophotometry. (2004) (28)
- Insights into the H2O2‐driven catalytic mechanism of fungal lytic polysaccharide monooxygenases (2020) (28)
- Structural differences between wild-type NADP-dependent glutathione reductase from Escherichia coli and a redesigned NAD-dependent mutant. (1993) (28)
- On the evolution of alternate core packing in eightfold β/α‐barrels (1994) (28)
- Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling (2009) (27)
- Laser Excitation Studies of the Product Release Steps in the Catalytic Cycle of the Light-driven Enzyme, Protochlorophyllide Oxidoreductase* (2007) (27)
- Parallel Pathways and Free‐Energy Landscapes for Enzymatic Hydride Transfer Probed by Hydrostatic Pressure (2009) (27)
- Pressure effects on enzyme-catalyzed quantum tunneling events arise from protein-specific structural and dynamic changes. (2012) (27)
- Magnetic field effects as a result of the radical pair mechanism are unlikely in redox enzymes (2015) (26)
- Convergence of theory and experiment on the role of preorganization, quantum tunneling and enzyme motions into flavoenzyme-catalyzed hydride transfer. (2017) (26)
- Towards the free energy landscape for catalysis in mammalian nitric oxide synthases (2015) (26)
- Solvent-slaved protein motions accompany proton but not hydride tunneling in light-activated protochlorophyllide oxidoreductase. (2009) (26)
- Untangling Heavy Protein and Cofactor Isotope Effects on Enzyme-Catalyzed Hydride Transfer. (2016) (26)
- The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer (2008) (26)
- A Twin-track Approach Has Optimized Proton and Hydride Transfer by Dynamically Coupled Tunneling during the Evolution of Protochlorophyllide Oxidoreductase* (2011) (25)
- Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395. (2004) (25)
- Energy Landscapes and Catalysis in Nitric-oxide Synthase* (2014) (25)
- Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase (2009) (25)
- Reduction of aliphatic nitroesters and N‐nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase (2008) (25)
- Real‐time analysis of conformational control in electron transfer reactions of human cytochrome P450 reductase with cytochrome c (2015) (25)
- Bio-derived Production of Cinnamyl Alcohol via a Three Step Biocatalytic Cascade and Metabolic Engineering. (2018) (25)
- Reaction of Morphinone Reductase with 2-Cyclohexen-1-one and 1-Nitrocyclohexene (2005) (24)
- Chemo-enzymatic routes towards the synthesis of bio-based monomers and polymers (2019) (24)
- Ultrafast Red Light Activation of Synechocystis Phytochrome Cph1 Triggers Major Structural Change to Form the Pfr Signalling-Competent State (2012) (24)
- Origin of the Proton-transfer Step in the Cofactor-free (1H)-3-Hydroxy-4-oxoquinaldine 2,4-Dioxygenase (2014) (24)
- An Internal Reaction Chamber in Dimethylglycine Oxidase Provides Efficient Protection from Exposure to Toxic Formaldehyde* (2009) (23)
- A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes (2018) (23)
- Tyrosyl Radical Formation and Propagation in Flavin Dependent Monoamine Oxidases (2010) (23)
- Role of histidine 42 in ascorbate peroxidase. Kinetic analysis of the H42A and H42E variants. (2002) (23)
- Cyclometalated Ir(III) complexes of deprotonated N-methylbipyridinium ligands: effects of quaternised N centre position on luminescence. (2015) (22)
- Continuous two-phase flow miniaturised bioreactor for monitoring anaerobic biocatalysis by pentaerythritol tetranitrate reductase. (2010) (22)
- An exposed tyrosine on the surface of trimethylamine dehydrogenase facilitates electron transfer to electron transferring flavoprotein: kinetics of transfer in wild-type and mutant complexes. (1997) (22)
- Directed mutagenesis of the redox-active disulphide bridge in glutathione reductase from Escherichia coli (1990) (22)
- Selective modification of alkylammonium ion specificity in trimethylamine dehydrogenase by the rational engineering of cation-pi bonding. (1997) (22)
- Electro-enzymatic viologen-mediated substrate reduction using pentaerythritol tetranitrate reductase and a parallel, segmented fluid flow system (2013) (22)
- Driving Force Analysis of Proton Tunnelling Across a Reactivity Series for an Enzyme‐Substrate Complex (2008) (21)
- A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids. (2018) (21)
- Experiment and Simulation Reveal How Mutations in Functional Plasticity Regions Guide Plant Monoterpene Synthase Product Outcome. (2018) (21)
- Introduction. Quantum catalysis in enzymes: beyond the transition state theory paradigm (2006) (21)
- Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol (2020) (21)
- Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins (2011) (21)
- Enzyme engineering toolbox – a ‘catalyst’ for change (2013) (20)
- Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries (2019) (20)
- Exploring novel bacterial terpene synthases (2020) (20)
- Laser‐flash photolysis indicates that internal electron transfer is triggered by proton uptake by Alcaligenes xylosoxidans copper‐dependent nitrite reductase (2012) (20)
- Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase (2015) (20)
- PartsGenie: an integrated tool for optimising and sharing synthetic biology parts (2017) (20)
- Recombinant two-iron rubredoxin of Pseudomonas oleovorans: overexpression, purification and characterization by optical, CD and 113Cd NMR spectroscopies. (1997) (19)
- A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites (2019) (19)
- Water-soluble Ir(iii) complexes of deprotonated N-methylbipyridinium ligands: fluorine-free blue emitters. (2015) (19)
- Differential coupling through Val-344 and Tyr-442 of trimethylamine dehydrogenase in electron transfer reactions with ferricenium ions and electron transferring flavoprotein. (2000) (19)
- Synthetic biology for fibres, adhesives and active camouflage materials in protection and aerospace. (2019) (19)
- Excited state dynamics can be used to probe donor-acceptor distances for H-tunneling reactions catalyzed by flavoproteins. (2013) (19)
- Nanofibrillar Peptide Hydrogels for the Immobilization of Biocatalysts for Chemical Transformations (2014) (19)
- Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation. (2008) (19)
- Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes (2012) (19)
- Time-resolved studies of radical pairs. (2009) (19)
- Formation of W3A1 Electron-transferring Flavoprotein (ETF) Hydroquinone in the Trimethylamine Dehydrogenase·ETF Protein Complex* (2000) (19)
- Alternative metabolic pathways and strategies to high-titre terpenoid production in Escherichia coli (2021) (19)
- Probing active site geometry using high pressure and secondary isotope effects in an enzyme-catalysed 'deep' H-tunnelling reaction. (2010) (19)
- Enzymatic single-molecule kinetic isotope effects. (2013) (19)
- Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR) (2016) (19)
- The Role of Tyr-169 of Trimethylamine Dehydrogenase in Substrate Oxidation and Magnetic Interaction between FMN Cofactor and the 4Fe/4S Center* (1999) (18)
- Mechanistic aspects of the covalent flavoprotein dimethylglycine oxidase of Arthrobacter globiformis studied by stopped-flow spectrophotometry. (2002) (18)
- Publisher Correction: Photocatalysis as the ‘master switch’ of photomorphogenesis in early plant development (2021) (18)
- Electron tunneling in substrate-reduced trimethylamine dehydrogenase: kinetics of electron transfer and analysis of the tunneling pathway. (1995) (18)
- Electron Transfer and Conformational Change in Complexes of Trimethylamine Dehydrogenase and Electron Transferring Flavoprotein* (2002) (18)
- Ab Initio QM/MM Modeling of the Rate-Limiting Proton Transfer Step in the Deamination of Tryptamine by Aromatic Amine Dehydrogenase. (2017) (18)
- The Flavinylation Reaction of Trimethylamine Dehydrogenase. (1995) (18)
- Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy. (2007) (18)
- Using trimethylamine dehydrogenase in an enzyme linked amperometric electrode. Part 1. Wild-type enzyme redox mediation. (2003) (18)
- Effects of multiple ligand binding on kinetic isotope effects in PQQ-dependent methanol dehydrogenase. (2003) (17)
- An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme (2016) (17)
- Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy. (2004) (17)
- Flavinylation in wild-type trimethylamine dehydrogenase and differentially charged mutant enzymes: a study of the protein environment around the N1 of the flavin isoalloxazine. (1996) (17)
- Isopentenol Utilization Pathway for the Production of Linalool in Escherichia coli Using an Improved Bacterial Linalool/Nerolidol Synthase (2021) (17)
- An ultracentrifugal approach to quantitative characterization of the molecular assembly of a physiological electron-transfer complex: the interaction of electron-transferring flavoprotein with trimethylamine dehydrogenase. (1997) (17)
- Flavoenzyme catalysed oxidation of amines: roles for flavin and protein-based radicals. (2005) (17)
- Engineering the “Missing Link” in Biosynthetic (−)-Menthol Production: Bacterial Isopulegone Isomerase (2018) (17)
- Active site complementation in engineered hetero-dimers of Escherichia coli glutathione reductase created in vivo (1990) (16)
- Mechanistic Reappraisal of Early Stage Photochemistry in the Light-Driven Enzyme Protochlorophyllide Oxidoreductase (2012) (16)
- The effect of terminal globular domains on the response of recombinant mini-spidroins to fiber spinning triggers (2020) (16)
- Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale. (2007) (16)
- Ene‐reductases and their Applications (2016) (16)
- Degradation of explosives by nitrate ester reductases. (2001) (16)
- Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases (2016) (16)
- Syntheses and electronic and optical properties of complexes of the bis(2,2′-bipyrazyl)ruthenium unit (2015) (15)
- Enzymes make light work of hydrocarbon production (2017) (15)
- A perspective on conformational control of electron transfer in nitric oxide synthases (2017) (15)
- Crystal structure and solution characterization of the activation domain of human methionine synthase (2007) (15)
- Retooling microorganisms for the fermentative production of alcohols. (2018) (15)
- Reaction of the C30A Mutant of Trimethylamine Dehydrogenase with Diethylmethylamine* (1996) (15)
- Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions. (2008) (15)
- Correction to “Discovery, Characterization, Engineering and Applications of Ene-Reductases for Industrial Biocatalysis” (2018) (15)
- In silico design and automated learning to boost next-generation smart biomanufacturing (2020) (15)
- The evolving art of creating genetic diversity: From directed evolution to synthetic biology (2021) (14)
- Comprehensive Analysis of the Green-to-Blue Photoconversion of Full-Length Cyanobacteriochrome Tlr0924 (2014) (14)
- Renewable and tuneable bio-LPG blends derived from amino acids (2020) (14)
- ELDOR Spectroscopy Reveals that Energy Landscapes in Human Methionine Synthase Reductase are Extensively Remodelled Following Ligand and Partner Protein Binding (2011) (14)
- The Photoinitiated Reaction Pathway of Full-length Cyanobacteriochrome Tlr0924 Monitored Over 12 Orders of Magnitude* (2014) (14)
- Cross-Species Analysis of Protein Dynamics Associated with Hydride and Proton Transfer in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase. (2016) (14)
- Identification of covalent flavoproteins and analysis of the covalent link. (1999) (14)
- Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase (2019) (14)
- An automated pipeline for the screening of diverse monoterpene synthase libraries (2019) (14)
- Redox cycles in trimethylamine dehydrogenase and mechanism of substrate inhibition. (1999) (14)
- Protein recognition of ammonium cations using side‐chain aromatics: A structural variation for secondary ammonium ligands (1995) (14)
- A guide to time‐resolved structural analysis of light‐activated proteins (2021) (14)
- Chemoenzymatic Synthesis of the Intermediates in the Peppermint Monoterpenoid Biosynthetic Pathway. (2018) (14)
- Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase‐cytochrome P450 3A4 in nanodiscs (2017) (14)
- Protein Conformational Change Is Essential for Reductive Activation of Lytic Polysaccharide Monooxygenase by Cellobiose Dehydrogenase (2020) (14)
- Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition? (2021) (13)
- Structure of the Cannabis sativa olivetol‐producing enzyme reveals cyclization plasticity in type III polyketide synthases (2019) (13)
- Engineering surface charge. 2. A method for purifying heterodimers of Escherichia coli glutathione reductase. (1992) (13)
- Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap (2016) (13)
- Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase. (2011) (13)
- X-ray Scattering Studies of Methylophilus methylotrophus (sp. W3A1) Electron-transferring Flavoprotein (2000) (13)
- Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase. (2012) (13)
- Dynamic, Electrostatic Model for the Generation and Control of High-Energy Radical Intermediates by a Coenzyme B12-Dependent Enzyme (2013) (13)
- A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites (2019) (13)
- Structural insights into the ene-reductase synthesis of profens. (2017) (13)
- Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker’s Yeast (2020) (13)
- Two-iron rubredoxin of Pseudomonas oleovorans: production, stability and characterization of the individual iron-binding domains by optical, CD and NMR spectroscopies. (2001) (13)
- Nuclear quantum tunnelling in enzymatic reactions--an enzymologist's perspective. (2015) (13)
- Tripping the light fantastic in membrane redox biology: linking dynamic structures to function in ER electron transfer chains (2019) (12)
- Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain. (2009) (12)
- Chapter 9:Probing Coupled Motions in Enzymatic Hydrogen Tunnelling Reactions: Beyond Temperature-Dependence Studies of Kinetic Isotope Effects (2009) (12)
- Reductive half-reaction of the H172Q mutant of trimethylamine dehydrogenase: evidence against a carbanion mechanism and assignment of kinetically influential ionizations in the enzyme-substrate complex. (1999) (12)
- Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis (2019) (12)
- Solvent as a probe of active site motion and chemistry during the hydrogen tunnelling reaction in morphinone reductase. (2008) (12)
- Making molecules with photodecarboxylases: a great start or a false dawn? (2021) (12)
- Internal electron transfer in multi-site redox enzymes is accessed by laser excitation of thiouredopyrene-3,6,8-trisulfonate (TUPS). (2009) (11)
- Proton tunnelling and promoting vibrations during the oxidation of ascorbate by ferricyanide? (2014) (11)
- The sacrificial inactivation of the blue-light photosensor cryptochrome from Drosophila melanogaster† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cp04671a (2018) (11)
- Using trimethylamine dehydrogenase in an enzyme linked amperometric electrode (2003) (11)
- Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin. (2001) (11)
- Flavins and flavoproteins 2002 (2002) (11)
- Crystal structure of DMGO provides a prototype for a new tetrahydrofolate-binding fold. (2005) (11)
- Nonequivalence of Second Sphere “Noncatalytic” Residues in Pentaerythritol Tetranitrate Reductase in Relation to Local Dynamics Linked to H-Transfer in Reactions with NADH and NADPH Coenzymes (2018) (11)
- Correction of pre-steady-state KIEs for isotopic impurities and the consequences of kinetic isotope fractionation. (2008) (11)
- A surprising observation that oxygen can affect the product enantiopurity of an enzyme‐catalysed reaction (2012) (11)
- Non-covalent protein-based adhesives for transparent substrates—bovine serum albumin vs. recombinant spider silk (2020) (10)
- Atomic Level Insight into the Oxidative Half-reaction of Aromatic Amine Dehydrogenase* (2006) (10)
- Solution structure of the two-iron rubredoxin of Pseudomonas oleovorans determined by NMR spectroscopy and solution X-ray scattering and interactions with rubredoxin reductase. (2004) (10)
- Probing the dynamic interface between trimethylamine dehydrogenase (TMADH) and electron transferring flavoprotein (ETF) in the TMADH-2ETF complex: role of the Arg-alpha237 (ETF) and Tyr-442 (TMADH) residue pair. (2008) (10)
- Colworth Medal Lecture. Enzymes in the quantum world. (1999) (10)
- Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases. (2020) (10)
- Identification of N-terminal regions of wheat leaf ferredoxin NADP+ oxidoreductase important for interactions with ferredoxin. (2011) (10)
- Kinetic isotope effects and ligand binding in PQQ-dependent methanol dehydrogenase. (2005) (10)
- Solvent-slaved protein motions accompany proton coupled electron transfer reactions catalysed by copper nitrite reductase. (2019) (10)
- Computational studies of enzyme mechanism: linking theory with experiment in the analysis of enzymic H-tunnelling. (2006) (10)
- A designed mutant of the enzyme glutathione reductase shortens the crystallization time by a factor of forty. (1994) (10)
- Multifragment DNA Assembly of Biochemical Pathways via Automated Ligase Cycling Reaction. (2018) (10)
- Mechanistic aspects and redox properties of hyperthermophilic L‐proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase/oxidase (2007) (10)
- Reaction of Vascular Adhesion Protein-1 (VAP-1) with Primary Amines (2011) (10)
- New Insights into the Reductive Half-reaction Mechanism of Aromatic Amine Dehydrogenase Revealed by Reaction with Carbinolamine Substrates* (2007) (9)
- Dual role of the active site ‘lid’ regions of protochlorophyllide oxidoreductase in photocatalysis and plant development (2020) (9)
- From Bugs to Bioplastics: Total (+)‐Dihydrocarvide Biosynthesis by Engineered Escherichia coli (2019) (9)
- Quantum catalysis in enzymes: beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005 (2006) (9)
- SYNBIOCHEM–a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals (2016) (9)
- Practical aspects on the use of kinetic isotope effects as probes of flavoprotein enzyme mechanisms. (2014) (9)
- Two-electron reduction of quinones by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships. (2007) (9)
- Does the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H‐transfer reactions? (2015) (9)
- 7.11 Reduction: Enantioselective Bioreduction of C–C Double Bonds (2012) (9)
- C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones† (2019) (9)
- Characterization of coenzyme binding and selectivity determinants in Mycobacterium tuberculosis flavoprotein reductase A: analysis of Arg(199) and Arg(200) mutants at the NADP(H) 2'-phosphate binding site. (2009) (9)
- Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases (2016) (8)
- 1H, 15N and 13C backbone resonance assignments of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2 (2017) (8)
- Mechanism of FAD reduction and role of active site residues His-225 and Tyr-259 in Arthrobacter globiformis dimethylglycine oxidase: analysis of mutant structure and catalytic function. (2006) (8)
- Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes (2002) (8)
- Consolidated Bioprocessing: Synthetic Biology Routes to Fuels and Fine Chemicals (2021) (8)
- Selectivity through discriminatory induced fit enables switching of NAD(P)H coenzyme specificity in Old Yellow Enzyme ene‐reductases (2019) (8)
- Major Structural Reorganisation Most Likely Accompanies the Transient Formation of a Physiological Electron Transfer Complex (1998) (8)
- Streamlining Natural Products Biomanufacturing With Omics and Machine Learning Driven Microbial Engineering (2020) (8)
- Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis (2005) (8)
- Biodiversity of cytochrome P 450 redox systems (2005) (8)
- Evidence for protein conformational change at a Au(110)/protein interface (2008) (8)
- Photochemical Mechanism of an Atypical Algal Phytochrome (2018) (8)
- Low temperature solution behaviour of Methylophilus methylotrophus electron transferring flavoprotein: a study by analytical ultracentrifugation (1997) (8)
- Conformational changes in the catalytic cycle of protochlorophyllide oxidoreductase: what lessons can be learnt from dihydrofolate reductase? (2009) (8)
- Crystallization and preliminary diffraction studies of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2. (1998) (8)
- Crystallization and preliminary diffraction studies of morphinone reductase, a flavoprotein involved in the degradation of morphine alkaloids. (1997) (7)
- Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation (2019) (7)
- Promoter engineering for microbial bio-alkane gas production (2020) (7)
- Probing Reversible Chemistry in Coenzyme B12-Dependent Ethanolamine Ammonia Lyase with Kinetic Isotope Effects (2015) (7)
- Kinetics of CO binding and CO photodissociation in Pseudomonas stutzeri cd(1) nitrite reductase: probing the role of extended N-termini in fast structural relaxation upon CO photodissociation. (2001) (7)
- Quantum mechanics/molecular mechanics studies on the mechanism of action of cofactor pyridoxal 5'-phosphate in ornithine 4,5-aminomutase. (2014) (7)
- Direct Evidence of an Excited-State Triplet Species upon Photoactivation of the Chlorophyll Precursor Protochlorophyllide. (2017) (7)
- New insights into the multi-step reaction pathway of the reductive half-reaction catalysed by aromatic amine dehydrogenase: a QM/MM study. (2010) (7)
- Assignment of the vibrational spectra of enzyme-bound tryptophan tryptophyl quinones using a combined QM/MM approach. (2010) (7)
- Excited-State Properties of Protochlorophyllide Analogues and Implications for Light-Driven Synthesis of Chlorophyll. (2017) (7)
- Blood, sweat, and tears: extraterrestrial regolith biocomposites with in vivo binders (2021) (7)
- Catalysis by the isolated tryptophan tryptophylquinone-containing subunit of aromatic amine dehydrogenase is distinct from native enzyme and synthetic model compounds and allows further probing of TTQ mechanism. (2008) (6)
- Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range (2013) (6)
- Photochemical Spin Dynamics of the Vitamin B12 Derivative, Methylcobalamin. (2019) (6)
- Cytochromes P 450 : novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis (2003) (6)
- Active Intermediates in Copper Nitrite Reductase Reactions Probed by a Cryotrapping‐Electron Paramagnetic Resonance Approach (2020) (6)
- Rubredoxin/rubredoxin reductase of Pseudomonas oleovorans: a model system for investigating interprotein electron transfer. (1996) (6)
- Selective cellular imaging with lanthanide‐based upconversion nanoparticles (2019) (6)
- Engineering surface charge. 1. A method for detecting subunit exchange in Escherichia coli glutathione reductase. (1992) (6)
- Enzyme immobilisation on wood-derived cellulose scaffolds via carbohydrate-binding module fusion constructs (2021) (6)
- H-transfers in Photosystem II: what can we learn from recent lessons in the enzyme community? (2008) (6)
- Graphene-aramid nanocomposite fibres via superacid co-processing. (2019) (5)
- Trp(359) regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA. (2008) (5)
- Special Issue: Flavins and Flavoproteins (2015) (5)
- Design and fabrication of recombinant reflectin-based multilayer reflectors: bio-design engineering and photoisomerism induced wavelength modulation (2021) (5)
- Combinatorial use of environmental stresses and genetic engineering to increase ethanol titres in cyanobacteria (2021) (5)
- Controlling the formation of a monolayer of cytochrome P450 reductase onto Au surfaces. (2012) (5)
- A Biological Route to Conjugated Alkenes: Microbial Production of Hepta-1,3,5-triene. (2020) (5)
- Quantum Effects in Enzyme Kinetics (2009) (5)
- Flavin doesn’t put all oxygens in one basket (2020) (5)
- Engineering nature for gaseous hydrocarbon production (2020) (5)
- A Conformational Sampling Model for Radical Catalysis in Pyridoxal Phosphate- and Cobalamin-dependent Enzymes* (2014) (5)
- Trimethylamine dehydrogenase and electron transferring flavoprotein. (2000) (5)
- Author Correction: Building a global alliance of biofoundries (2019) (4)
- Flavocytochrome P 450 BM 3 and the origin of CYP 102 fusion species (2006) (4)
- Photocycle of Cyanobacteriochrome TePixJ (2020) (4)
- Electron transfer in trimethylamine dehydrogenase and electron-transferring flavoprotein. (1999) (4)
- Observation of the Δg mechanism resulting from the ultrafast spin dynamics that follow the photolysis of coenzyme B12. (2019) (4)
- Conformational change induced by electron transfer in a monolayer of cytochrome P450 reductase adsorbed at the Au(110)-phosphate buffer interface. (2013) (4)
- Solution and computational studies of kinetic isotope effects in flavoprotein and quinoprotein catalyzed substrate oxidations as probes of enzymic hydrogen tunneling and mechanism (2005) (4)
- A plasmid toolset for CRISPR‐mediated genome editing and CRISPRi gene regulation in Escherichia coli (2021) (4)
- Exploiting Single Domain Antibodies as Regulatory Parts to Modulate Monoterpenoid Production in E. coli. (2020) (4)
- Distributed Biomanufacturing of Liquefied Petroleum Gas (2019) (3)
- Probing the stabilizing role of C-terminal residues in trimethylamine dehydrogenase. (1998) (3)
- Isotope effects reveal that para-substituted benzylamines are poor reactivity probes of the quinoprotein mechanism for aromatic amine dehydrogenase. (2007) (3)
- Mutation in a chlorophyll-binding motif of Brassica ferrochelatase enhances both heme and chlorophyll biosynthesis. (2022) (3)
- Isotopically labeled flavoenzymes and their uses in probing reaction mechanisms. (2019) (3)
- What are the signatures of tunnelling in enzyme-catalysed reactions? (2019) (3)
- Structure-Based Insight into the Asymmetric Bioreduction of the C=C Double Bond of α,β-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase (2010) (3)
- Flavoprotein disulphide oxidoreductases: protein engineering of glutathione reductase from Escherichia coli. (1988) (3)
- Co‐production of biofuel, bioplastics and biochemicals during extended fermentation of Halomonas bluephagenesis (2022) (3)
- Ultrafast Vibrational Energy Transfer between Protein and Cofactor in a Flavoenzyme (2020) (3)
- Lys-D48 Is Required for Charge Stabilization, Rapid Flavin Reduction, and Internal Electron Transfer in the Catalytic Cycle of Dihydroorotate Dehydrogenase B of Lactococcus lactis* (2006) (3)
- How Photoactivation Triggers Protochlorophyllide Reduction: Computational Evidence of a Stepwise Hydride Transfer during Chlorophyll Biosynthesis (2022) (3)
- The influence of the structure of the Au(110) surface on the ordering of a monolayer of cytochrome P450 reductase at the Au(110)/phosphate buffer interface (2014) (2)
- Electron Transfer Flavoproteins (2020) (2)
- Conformational change in cytochrome P450 reductase adsorbed at a Au(110)-phosphate buffer interface induced by interaction with nicotinamide adenine dinucleotide phosphate. (2014) (2)
- Professor Richard Nelson Perham. (2015) (2)
- Thermal, electrochemical and photochemical reactions involving catalytically versatile ene reductase enzymes. (2020) (2)
- Enzyme mechanisms: fast reaction and computational approaches. (2009) (2)
- Glutamate 338 is an electrostatic facilitator of C–Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase (2015) (2)
- Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase (2007) (2)
- Expression and thermodynamic characterisation of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA (2002) (2)
- The Old Yellow Enzyme family of flavoenzymes comparison of substrate specificity and activity against explosives (1999) (2)
- Prototyping of microbial chassis for the biomanufacturing of high-value chemical targets. (2021) (2)
- Crystallization and preliminary X-ray diffraction analysis of a flavoenzyme amine dehydrogenase/oxidase from Pyrococcus furiosus DSM 3638. (2005) (2)
- Combined Pulsed Electron Double Resonance EPR and Molecular Dynamics Investigations of Calmodulin Suggest Effects of Crowding Agents on Protein Structures (2022) (2)
- Design and fabrication of recombinant reflectin-based Bragg reflectors: bio-design engineering and photoisomerism induced wavelength modulation (2020) (2)
- Trapping methods for probing functional intermediates in nitric oxide synthases and related enzymes. (2018) (2)
- Homodimeric and expanded behaviour of trimethylamine dehydrogenase in solution at different temperatures (1996) (2)
- How a 10-epi-Cubebol Synthase Avoids Premature Reaction Quenching to Form a Tricyclic Product at High Purity (2022) (2)
- Speeding up enzyme engineering computationally (2016) (2)
- Electron transfer in the reductase domain of neuronal nitric oxide synthase (2002) (2)
- Relaxation kinetics of cytochrome P450 reductase (2002) (2)
- Hierarchically Porous Silk/Activated-Carbon Composite Fibres for Adsorption and Repellence of Volatile Organic Compounds (2020) (2)
- Predictive Engineering of Class I Terpene Synthases Using Experimental and Computational Approaches (2021) (2)
- 1H, 15N, 13C backbone resonance assignments of human soluble catechol O-methyltransferase in complex with S-adenosyl-l-methionine and 3,5-dinitrocatechol (2016) (2)
- Electron transfer in flavocytochrome P450 BM3 and the C999A mutant: kinetics of flavin reduction and relationships with mammalian cytochrome P450 reductase (2003) (2)
- Biocatalyst identification by anaerobic high-throughput screening of enzyme libraries and anaerobic microorganisms (2012) (1)
- SYNBIOCHEM Design-Build-Test-Learn pipeline (2018) (1)
- Structure of the human MCAD:ETF complex (2004) (1)
- Mechanistic studies of Trp-102 mutant forms of pentaerythritol tetranitrate reductase (2002) (1)
- NLS : conceptual design report (2015) (1)
- Special issue: Catalytic mechanisms by biological systems (2013) (1)
- Flavins and flavoproteins 2002 : proceedings of the Fourteenth International Symposium, St.John's College, University of Cambridge, UK, July 14 - 18, 2002 (2002) (1)
- Formation of W3A1 ETF hydroquinone in the TMADH/ETF protein complex (1999) (1)
- Reduction of Nitroaromatic Explosives by Oxygen-Insensitive NAD(P)H:Nitroreductases: Implications for their Cytotoxicity and Biodegradation (2006) (1)
- Cytochrome P450 systems in Mycobacterium tuberculosis (2003) (1)
- Bioproduction of Linalool From Paper Mill Waste (2022) (1)
- Flavin radicals, conformational sampling and robust design principles in interprotein electron transfer: the trimethylamine dehydrogenase-electron-transferring flavoprotein complex. (2004) (1)
- Catalysis by Nature's photoenzymes. (2022) (1)
- Genome Editing for the Production of Natural Products in Escherichia coli (2018) (1)
- Molecular Determinants of Carbocation Cyclisation in Bacterial Monoterpene Synthases (2022) (1)
- Structure and mechanism of an opiate-transforming redox enzyme: Morphinone reductase (1999) (1)
- Pentaerythritol tetranitrate reductase : kinetic and structural basis of reactivity with NADPH , 2-cyclohexenone , nitroesters and nitroaromatic explosives (2002) (1)
- Crystal structures of recombinant wild-type and a C30A mutant of trimethylamine dehydrogenase from Methylophilus W3A1 (1996) (1)
- Solution-State Inter-Copper Distribution of Redox Partner-Linked Copper Nitrite Reductases: A Pulsed Electron–Electron Double Resonance Spectroscopy Study (2022) (1)
- Exploration of the coenzyme and substrate specificity of glutathione reductase and its subunit assembly (1990) (1)
- Building a global alliance of biofoundries (2019) (1)
- Publisher Correction: Photocatalysis as the ‘master switch’ of photomorphogenesis in early plant development (2021) (1)
- Electron transfer complex assembly: the association of trimethylamine dehydrogenase with electron transferring flavoprotein (1996) (1)
- Mechanism of Action of Flavin-Dependent Halogenases (2022) (1)
- Crystal structure of [1,1′′′-bis(pyrimidin-2-yl)-4,4′:2′,2′′:4′′,4′′′-quaterpyridine-1,1′′′-diium-κ2 N 1′,N 1′′]bis[2-(pyridin-2-yl)phenyl-κ2 N,C 1]iridium(III) tris(hexafluoridophosphate) acetonitrile trisolvate (2015) (1)
- Single crystal spectroscopy and multiple structures from one crystal (MSOX) define catalysis in copper nitrite reductases (2022) (1)
- Examining the importance of dynamics, barrier compression and hydrogen tunnelling in enzyme catalysed reactions (2011) (1)
- Building a global alliance of biofoundries (vol 10, 2040, 2019) (2019) (1)
- Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis (2019) (0)
- An unusual light-sensing function for coenzyme B12 in bacterial transcription regulator CarH. (2022) (0)
- The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease (2013) (0)
- Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate (2017) (0)
- Wild-type pentaerythritol tetranitrate reductase containing a C-terminal 8-histidine tag (2010) (0)
- Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase (2007) (0)
- Photoinduced Electron Transfer from a 1,4,5,6-Tetrahydro Nicotinamide Adenine Dinucleotide (Phosphate) Analogue to Oxidized Flavin in an Ene-Reductase Flavoenzyme (2023) (0)
- Isopiperitenone reductase from Mentha piperita in complex with NADP and beta-Cyclocitral (2016) (0)
- Substrate inhibition in wild-type and mutant trimethylamine dehydrogenases (1999) (0)
- Crystal Structure of the Thermostable NADH4-bound old yellow enzyme from Thermoanaerobacter pseudethanolicus E39 (2009) (0)
- Dissection of the FMN-binding site in trimethylamine dehydrogenase. (1995) (0)
- Hydrogen tunnelling in amine dehydrogenases from methylotrophic bacteria (1999) (0)
- Flavin oxidation state impacts on nitrofuran antibiotic binding orientation in nitroreductases. (2021) (0)
- Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity (2012) (0)
- Crystal structure of Pentaerythritol Tetranitrate Reductase complex with 1,4,5,6-tetrahydro NADH (2010) (0)
- Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis (2006) (0)
- Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo (2009) (0)
- Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus in complex with 2-fluorogeranyl diphosphate (2017) (0)
- Site-directed mutagenesis and the mechanism of flavoprotein disulphide oxidoreductases (1989) (0)
- Structures of carboxylic acid reductase reveal domain 1 dynamics underlying catalysis 2 3 (2017) (0)
- Bacterial terpene synthases neighbour-joining tree. (2020) (0)
- STRUCTURE OF THE N90S MUTANT OF NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite (2011) (0)
- Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folic acid (2003) (0)
- Erratum (2006) (0)
- StarCrete: a starch-based regolith biocomposite for extraterrestrial construction (2022) (0)
- Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein (2003) (0)
- STRUCTURE OF THE RECOMBINANT NATIVE NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite (2011) (0)
- Baseline proteomics characterisation of the emerging host biomanufacturing organism Halomonas bluephagenesis (2022) (0)
- Crystal Structure of ornithine 4,5 aminomutase backsoaked complex (2010) (0)
- Flavoprotein‐dependent Bioreduction (2021) (0)
- Hybrid molecules of glutathione reductase: tools for investigating protein interactions at the dimer interface (1994) (0)
- List of terpene synthases annotated in phylogenetic tree, Fig 1. (2020) (0)
- Trimethylamine dehydrogenase: mechanism and assembly of a complex iron-sulfur flavoprotein (1996) (0)
- Isopiperitenone reductase from Mentha piperita in complex with Isopiperitenone and NADP (2016) (0)
- Structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folinic acid (2003) (0)
- Plasmids used in this study. (2020) (0)
- Enantioselective bioreduction of carbon-carbon double bonds (2012) (0)
- Molecular recognition of organic ammonium cations by di- and trimethylamine dehydrogenases (1996) (0)
- The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - Truncated Construct (2015) (0)
- Moritella profunda dihydrofolate reductase (DHFR) (2009) (0)
- Crystal structure of the human ETF E165betaA mutant (2005) (0)
- Protein-protein interactions mapped by artificial proteases: where s factors bind to RNA (2000) (0)
- Isopiperitenone reductase from Mentha piperita in complex with NADP (2016) (0)
- Unravelling the complexity of enzyme catalysis (2023) (0)
- The reductive half-reaction of trimethylamine dehydrogenase with trimethylamine (1999) (0)
- Editorial overview: Catalysis and regulation: The chemistry of catalysis. (2022) (0)
- Barrier compression and tunneling in enzyme catalysed reactions (2011) (0)
- Molecular enzymology of the diflavin reductases (2002) (0)
- Chemical Aspects of Amine Oxidation by Flavoprotein Enzymes (2005) (0)
- Modified amine dehydrogenases with variable substrate specificity (1997) (0)
- Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase (2009) (0)
- Crystal structure of XenA from Pseudomonas putida in complex with an NADH mimic (mAc) (2016) (0)
- Mechanism and regulation of electron transfer in cytochrome P450 redox systems (2003) (0)
- Structure and mechanism of an explosives-degrading enzyme: PETN reductase (1999) (0)
- Crystal structure of nitrite bound synthetic core domain of nitrite reductase from Ralstonia pickettii (residues 1-331) (2019) (0)
- Menthone neomenthol reductase from Mentha piperita in complex with NADP (2016) (0)
- Reduction of diflavin enzymes by photoexcitable thiouredopyrene-3,6,8-trisulfonate (TUPS) (2008) (0)
- STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT WILD TYPE TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1) (1999) (0)
- Flavinylation of the trimethylamine dehydrogenase of bacterium W3A1 expressed in Escherichia coli (1994) (0)
- Natural Product Biosynthesis in Escherichia coli: Mentha Monoterpenoids. (2016) (0)
- Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with 2-phenylacrylic acid (2017) (0)
- Structure of morphinone reductase in complex with tetrahydroNAD (2008) (0)
- XenA from Pseudomonas putida in complex with NADPH4. (2016) (0)
- Structure of electron transferring flavoprotein from Methylophilus methylotrophus, recognition loop removed by limited proteolysis (2003) (0)
- Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase (mutant A134F) (2013) (0)
- Inside Cover: Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries (ChemBioChem 17/2010) (2010) (0)
- Professor Richard Nelson Perham, FRS, FMedSci (2015) (0)
- Conversion of Alcohols to Enantiopure Amines Through Dual‐Enzyme Hydrogen‐Borrowing Cascades. (2016) (0)
- The effect of terminal globular domains on the response of recombinant mini-spidroins to fiber spinning triggers (2020) (0)
- Pentaerythritol tetranitrate reductase co-crystal structure containing a bound (E)-1-(4'-hydroxyphenyl)-2-nitroethene molecule (2011) (0)
- SYNBIOCHEM - Combinatorial plasmid libraries for material monomer production in Escherichia coli. (2019) (0)
- Protein engineering of glutathione reductase from Escherichia coli. (1987) (0)
- Bacterial morphinone reductase: active site structure and properties of active site mutant enzymes (2002) (0)
- CRYSTAL STRUCTURE OF DITHIONITE-REDUCED AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS IN COMPLEX WITH TRYPTAMINE (2006) (0)
- Electron transfer in ω-hydroxylation: analysis of rubredoxin reductase and rubredoxin (1999) (0)
- Crystal structure of aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis (2006) (0)
- X-ray Crystal Structure of a NADP(H)-bound Double Bond Reductase from Nicotiana tabacum (2013) (0)
- X-ray Crystal Structure of a Ternary Complex of Double Bond Reductase from Nicotiana tabacum (2013) (0)
- Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus (2017) (0)
- Microsoft Word-HOD paper revised final (2014) (0)
- STRUCTURE OF F306C MUTANT OF NITRITE REDUCTASE FROM Achromobacter XYLOSOXIDANS WITH NITRITE BOUND (2014) (0)
- Menthone neomenthol reductase from Mentha piperita (2016) (0)
- Simulation Reveal How Mutations in Functional Plasticity Regions Guide (2018) (0)
- Electron transfer in trimethylamine dehydrogenase: directed mutagenesis of a potential tunneling pathway. (1996) (0)
- Hierarchically Porous Silk/Activated-Carbon Composite Fibers for Adsorption and Repellence of Volatile Organic Compounds (2020) (0)
- Kinetic mechanism of dimethylglycine oxidase (2002) (0)
- Electron transfer in the alkane hydroxylase system of Pseudomonas oleovorans (2002) (0)
- Stepwise electron transfer to 6-S cysteinyl FMN in trimethylamine dehydrogenase (1999) (0)
- An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals (2018) (0)
- Analysis of flavin dynamics and thermodynamics using EPR and potentiometric methods (2005) (0)
- STRUCTURE OF THE F306C MUTANT OF NITRITE REDUCTASE FROM Achromobacter XYLOSOXIDANS (2014) (0)
- Structural basis for light-driven enzyme catalysis in chlorophyll biosynthesis (2019) (0)
- Crystal structure of D552A dimethylglycine oxidase mutant of Arthrobacter globiformis in complex with tetrahydrofolate (2009) (0)
- StarCrete: A starch-based biocomposite for off-world construction (2023) (0)
- Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Anaerobic) (2010) (0)
- Chapter 10:Computational Simulations of Tunnelling Reactions in Enzymes (2009) (0)
- H184N mutant of pentaerythritol tetranitrate reductase containing bound acetate ion (2011) (0)
- Probing the reductive reaction of the FAD and CPR domains of flavocytochrome P450 BM3 (2002) (0)
- Reductases Transfer in the Copper-containing Nitrite Demonstration of Proton-coupled Electron Enzyme Catalysis and Regulation : (2009) (0)
- Model structure of electron transferring flavoprotein from Methylophilus methylotropus (CA coordinates) (2000) (0)
- Active site mutants of the glutathione reductase from Escherichia coli (1990) (0)
- Protein engineering of glutathione reductase: over-expression of the gene from Escherichia coli (1986) (0)
- Pentaerythritol tetranitrate reductase co-crystal structure containing bound (E)-1-(3'-hydroxyphenyl)-2-nitroethene (2011) (0)
- Editorial overview: Catalysis and regulation: enzyme structure, mechanism, and biosynthetic pathways. (2016) (0)
- Automatic translation of high ‐ level bio ‐ designs into wet ‐ lab protocols through learning and formalizing expert ’ s practices (2015) (0)
- Front Cover: Photochemical Mechanism of an Atypical Algal Phytochrome (ChemBioChem 10/2018) (2018) (0)
- H181N mutant of pentaerythritol tetranitrate reductase containing a C-terminal His8-tag (2011) (0)
- GeneORator: An Efficient Method for the Systematic Mutagenesis of Entire Genes. (2022) (0)
- Promoting motions facilitate nuclear tunneling in flavoprotein enzymes (2008) (0)
- Biocatalytic Hydrogen-Borrowing Amination of Ketones (2015) (0)
- Cytochrome c Fused Copper Nitrite Reductases (2021) (0)
- Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form (2006) (0)
- Crystal Structure of ORNITHINE 4,5 AMINOMUTASE in complex with 2,4-diaminobutyrate (DAB) (Aerobic) (2010) (0)
- Robotic high-throughput screening of pentaerythritol tetranitrate reductase mutants for the generation of useful biocatalysts (2008) (0)
- Crystal Structure of kynurenine 3-monooxygenase - truncated at position 394 plus HIS tag cleaved. (2013) (0)
- Author Correction: Building a global alliance of biofoundries (2019) (0)
- Experimental approaches towards proton-coupled electron transfer reactions in biological redox systems (2011) (0)
- Investigating the mechanism of C-H bond breakage in heterotetrameric sarcosine oxidase from Arthrobacter sp 1-IN (1999) (0)
- Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate and 2-fluorogeranyl diphosphate (2017) (0)
- NerA from Agrobacterium radiobacter in complex with 2-phenylacrylic acid (2017) (0)
- Protein sequences of selected terpene synthases. (2020) (0)
- The crystal structure of Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with a nicotinamide mimic (mNH2) (2016) (0)
- CRYSTAL STRUCTURE OF DITHIONITE-REDUCED AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS (2006) (0)
- Baseline proteomics characterisation of the emerging host biomanufacturing organism Halomonas bluephagenesis (2022) (0)
- Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N (2006) (0)
- Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound (2013) (0)
- Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se) (2013) (0)
- Introduction to quantum behavior - a primer.: Chapter 2 (2009) (0)
- Catalytic mechanisms by biological systems : Special issue introduction (2013) (0)
- Caged Compounds as Light-Dependent Initiators for Enzyme Catalysis Reactions (2017) (0)
- Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate (2003) (0)
- Substrate inhibition in trimethylamine dehydrogenase (1999) (0)
- Crystal Structure of the Thermostable Old Yellow Enzyme from Thermoanaerobacter pseudethanolicus E39 (2009) (0)
- Hydrogen Tunneling in Enzyme-Catalyzed Hydrogen Transfer: Aspects from Flavoprotein Catalysed Reactions (2006) (0)
- Structure of the human MCAD:ETF E165betaA complex (2005) (0)
- CRYSTAL STRUCTURE OF N-QUINOL FORM OF AROMATIC AMINE DEHYDROGENASE (AADH) FROM ALCALIGENES FAECALIS, FORM A COCRYSTAL (2006) (0)
- SITE-DIRECTED MUTAGENESIS AND TIIE MECHANISM OF FLAVOPROTEIN DISULPHIDE OXIDOREDUCfASES (1989) (0)
- 1H, 15N, 13C backbone resonance assignments of human soluble catechol O-methyltransferase in complex with S-adenosyl-l-methionine and 3,5-dinitrocatechol (2016) (0)
- Structure of electron transferring flavoprotein for Methylophilus methylotrophus. (2003) (0)
- 1H, 15N and 13C backbone resonance assignments of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2 (2017) (0)
- Subunit interactions in the glutathione reductase from Escherichia coli (1990) (0)
- High‐Titer Bio‐Styrene Production Afforded by Whole‐Cell Cascade Biotransformation (2023) (0)
- Cocrystal Structure of kynurenine 3-monooxygenase in complex with UPF 648 inhibitor(KMO-394UPF) (2013) (0)
- Ca2+-Calmodulin exerts thermodynamic and conformational regulation over electron transport in nNOS (2008) (0)
- A Toolbox for Diverse Oxyfunctionalisation of Monoterpenes (2018) (0)
- Structure and mechanism of an opiate-transforming enzyme: morphinone reductase (1999) (0)
- Transient kinetic analysis of the reductive half reaction of methionine synthase reductase (2002) (0)
- Crystal structure of as isolated Y323A mutant of haem-Cu containing nitrite reductase from Ralstonia pickettii (2019) (0)
- Y351A mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule (2011) (0)
- In conversation with Nigel Scrutton (2020) (0)
- Structure of morphinone reductase N189A mutant in complex with tetrahydroNAD (2009) (0)
- Integrating computational methods with experiment uncovers the role of dynamics in enzyme catalysed H-tunnelling reactions (2010) (0)
- An investigation of engineered cooperativity in mutants of Escherichia coli glutathione reductase (1993) (0)
- X-ray Crystal Structure of a Double Bond Reductase from Nicotiana tabacum (2013) (0)
- Structure of reduced PETN reductase in complex with progesterone (2005) (0)
- Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form (2006) (0)
- Crystal structure of cyclohexanone monooxygenase mutant (F249A, F280A and F435A) from Rhodococcus sp. Phi1 bound to NADP+ (2018) (0)
- pH dependence of monoamine oxidase A activity (2008) (0)
- Crystal structure of ornithine 4,5 aminomutase (Resting State) (2010) (0)
- Rubredoxin domain II from Pseudomonas oleovorans (2004) (0)
- Characterization of AIFM2: A novel human apoptosis inducing flavoprotein (2008) (0)
- Crystal structure of cyclohexanone monooxygenase from Rhodococcus sp. Phi1 bound to NADP+ (2018) (0)
- Crystallization and preliminary diffraction studies of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB 2 (1998) (0)
- Pentaerythritol tetranitrate reductase: reaction with NADPH, steroids, 2-cyclohexenone, nitroesters and nitroaromatic explosives (2002) (0)
- of the trimethylamine dehydrogenase of bacterium W3A1 expressed in Escherichia coli (1993) (0)
- Structure of PETN reductase Y186F in complex with cyanide (2005) (0)
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