Nikolaus Grigorieff
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Physics Biology
Nikolaus Grigorieff's Degrees
- PhD Biophysics Stanford University
- Masters Physics Stanford University
- Bachelors Physics Stanford University
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(Suggest an Edit or Addition)Nikolaus Grigorieff's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs. (2015) (3038)
- Accurate determination of local defocus and specimen tilt in electron microscopy. (2003) (1462)
- A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. (2002) (966)
- Electron-crystallographic refinement of the structure of bacteriorhodopsin. (1996) (845)
- Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6 (2015) (646)
- cisTEM, user-friendly software for single-particle image processing (2017) (627)
- Molecular model for a complete clathrin lattice from electron cryomicroscopy (2004) (511)
- FREALIGN: high-resolution refinement of single particle structures. (2007) (511)
- A Primer to Single-Particle Cryo-Electron Microscopy (2015) (430)
- Outcome of the First Electron Microscopy Validation Task Force Meeting (2012) (422)
- Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction (2008) (371)
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (2002) (364)
- Beam-induced motion of vitrified specimen on holey carbon film. (2012) (353)
- Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice. (1998) (341)
- The Ndc80 kinetochore complex forms oligomeric arrays along microtubules (2010) (293)
- Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils. (2009) (279)
- Likelihood-based classification of cryo-EM images using FREALIGN. (2013) (262)
- Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. (2012) (259)
- Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM (2015) (256)
- Three-Dimensional Structure of I to (2004) (249)
- Comparison of Alzheimer Aβ(1–40) and Aβ(1–42) amyloid fibrils reveals similar protofilament structures (2009) (242)
- Structural polymorphism of Alzheimer Aβ and other amyloid fibrils (2009) (233)
- High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus. (2007) (233)
- Atomic model of an infectious rotavirus particle (2010) (231)
- Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy (2015) (206)
- Conformational changes in the Arp2/3 complex leading to actin nucleation (2005) (192)
- Peptide dimer structure in an Aβ(1–42) fibril visualized with cryo-EM (2015) (184)
- Quantitative characterization of electron detectors for transmission electron microscopy. (2013) (182)
- Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy (2008) (179)
- Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating (2004) (179)
- SIGNATURE: a single-particle selection system for molecular electron microscopy. (2007) (178)
- Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase (2014) (172)
- Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1 (2010) (169)
- Frealign: An Exploratory Tool for Single-Particle Cryo-EM. (2016) (162)
- Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. (2011) (161)
- Activation of NMDA receptors and the mechanism of inhibition by ifenprodil (2016) (158)
- Subunit interactions in bovine papillomavirus (2010) (144)
- Noise bias in the refinement of structures derived from single particles. (2004) (142)
- Recent progress in understanding Alzheimer's β-amyloid structures. (2011) (141)
- Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM (2009) (139)
- Clathrin coats at 21 Å resolution: a cellular assembly designed to recycle multiple membrane receptors (1998) (139)
- Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution. (2001) (138)
- Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation (2018) (131)
- Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy (2011) (131)
- Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly (2009) (129)
- Ensemble cryo-EM elucidates the mechanism of translation fidelity (2017) (128)
- Projection structure of a ClC-type chloride channel at 6.5 Å resolution (2001) (127)
- Structure of the ribosome with elongation factor G trapped in the pretranslocation state (2013) (124)
- Ab initio resolution measurement for single particle structures. (2007) (118)
- Resolution measurement in structures derived from single particles. (2000) (116)
- Ribosome•RelA structures reveal the mechanism of stringent response activation (2016) (111)
- Visualization of the domain structure of an L-type Ca2+ channel using electron cryo-microscopy. (2003) (110)
- Automatic estimation and correction of anisotropic magnification distortion in electron microscopes. (2015) (110)
- Physical basis of amyloid fibril polymorphism (2018) (107)
- Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I) (1999) (107)
- Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome (2016) (106)
- Atomic Resolution Cryo-EM Structure of β-Galactosidase. (2018) (103)
- Structural complexity of a composite amyloid fibril. (2011) (89)
- Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids (2019) (85)
- Three-dimensional structure of C complex spliceosomes by electron microscopy (2004) (83)
- Direct visualisation of micelles of Pluronic block copolymers in aqueous solution by cryo-TEM (1999) (80)
- Quaternary structure of a mature amyloid fibril from Alzheimer's Abeta(1-40) peptide. (2006) (77)
- Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations. (2014) (76)
- Pentameric assembly of potassium channel tetramerization domain-containing protein 5. (2009) (70)
- Structure of the transporter associated with antigen processing trapped by herpes simplex virus (2016) (70)
- Nanoscale Flexibility Parameters of Alzheimer Amyloid Fibrils Determined by Electron Cryo-Microscopy** (2010) (70)
- Three-Dimensional Structure of Ito Kv4.2-KChIP2 Ion Channels by Electron Microscopy at 21 Å Resolution (2004) (66)
- Electron cryomicroscopy structure of N‐ethyl maleimide sensitive factor at 11 Å resolution (2003) (66)
- Ewald sphere correction for single-particle electron microscopy. (2006) (64)
- Structure of RNA polymerase bound to ribosomal 30S subunit (2017) (64)
- Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA–like structural element in the ribosomal decoding center (2014) (63)
- Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques. (2006) (63)
- Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles. (2012) (63)
- Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvβ2-subunit (2003) (62)
- Ito Channels Are Octomeric Complexes with Four Subunits of Each Kv4.2 and K+ Channel-interacting Protein 2* (2004) (57)
- Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril (2016) (57)
- Low-resolution structure refinement in electron microscopy. (2003) (56)
- Direct detection pays off for electron cryo-microscopy (2013) (55)
- Lipid location in deoxycholate-treated purple membrane at 2.6 A. (1995) (54)
- A dose-rate effect in single-particle electron microscopy. (2008) (53)
- Structure and assembly of calcium homeostasis modulator proteins (2019) (48)
- Single-protein detection in crowded molecular environments in cryo-EM images (2017) (45)
- Molecular Machines (2001) (44)
- Increased sulfate uptake by E. coli overexpressing the SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis. (2008) (42)
- GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors. (2010) (42)
- High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations (2019) (41)
- Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor (2019) (40)
- Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface (2012) (40)
- A maximum likelihood approach to two-dimensional crystals. (2007) (39)
- In situ structure determination at nanometer resolution using TYGRESS (2019) (38)
- Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. (2006) (38)
- Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter. (2012) (37)
- The three-dimensional arcitecture of the EJC core. (2006) (35)
- In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (2019) (34)
- An adaptation of the Wiener filter suitable for analyzing images of isolated single particles. (2011) (34)
- Mechanism of ribosome rescue by ArfA and RF2 (2016) (34)
- mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding (2020) (28)
- Three-dimensional structure of I(to); Kv4.2-KChIP2 ion channels by electron microscopy at 21 Angstrom resolution. (2004) (28)
- Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification. (2019) (27)
- Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia 1 (2010) (25)
- Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0. (2015) (25)
- Frealix: model-based refinement of helical filament structures from electron micrographs. (2014) (25)
- Locating macromolecular assemblies in cells by 2D template matching with cisTEM (2021) (24)
- Maturation in action: CryoEM study of a viral capsid caught during expansion. (2012) (20)
- CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. (2017) (17)
- Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction (2016) (15)
- Author response: Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6 (2015) (14)
- Interplay of DNA repair with transcription: from structures to mechanisms. (2012) (14)
- ! 1 ! Structure and conformational states of the bovine mitochondrial ATP synthase by cryo (2015) (14)
- Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer (2017) (13)
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs (2015) (12)
- Actin filament labels for localizing protein components in large complexes viewed by electron microscopy. (2009) (12)
- Structure of the ciliary axoneme at nanometer resolution reconstructed by TYGRESS (2018) (12)
- Cryo-TEM simulations of amorphous radiation-sensitive samples using multislice wave propagation (2021) (12)
- Author response: Ribosome•RelA structures reveal the mechanism of stringent response activation (2016) (11)
- Diffuse scattering in electron diffraction data from protein crystals (1995) (11)
- Comparison of calculated and observed dynamical diffraction from purple membrane: implications (1996) (10)
- Three-dimensional Structure of Bovine NADH : Ubiquinone Oxidoreductase ( Complex I ) at 22 AÊ in Ice (1998) (9)
- Electron microscopy of ultra-thin buried layers in InP and InGaAs (1993) (8)
- Cryo-EM structure of an amyloid fibril from systemic amyloidosis (2018) (7)
- Molecular Basis for Age-Dependent Microtubule Acetylation (2015) (5)
- Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs) (2014) (4)
- Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure) (2014) (4)
- Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1 (2017) (4)
- I to Channels Are Octomeric Complexes with Four Subunits of Each Kv4.2 and K (cid:1) Channel-interacting Protein 2* (2004) (4)
- Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins (2020) (3)
- Corrigendum to “A dose-rate effect in single-particle electron microscopy” [J. Struct. Biol. 161 (2008) 92–100] (2008) (3)
- Single particle cryo-EM structure of rotavirus VP6 at 2.6 Angstrom resolution (2015) (3)
- In situ single particle classification reveals distinct 60S maturation intermediates in cells (2022) (3)
- Electron diffraction of a bacterial ClC-type chloride channel. (2002) (2)
- High-Resolution Electron Microscopy of a Rotavirus Particle (2009) (2)
- Mechanistic Origins of Dynamic Instability in Filaments from the Phage Tubulin, PhuZ (2018) (2)
- Author response: Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome (2016) (2)
- Author response: Structure of RNA polymerase bound to ribosomal 30S subunit (2017) (2)
- Decision letter: Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases (2018) (2)
- The Three-dimensional Arc h itecture of the EJC Core (2006) (2)
- Analysis of Local Variability and Allostery in Macromolecular Assemblies using Cryo-EM and Focused Classification (2018) (1)
- Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections (2022) (1)
- Convergent beam electron diffraction and microscopy of interface atomic steps in InP/InGaAs single quantum wells (1991) (1)
- Author response: Single-protein detection in crowded molecular environments in cryo-EM images (2017) (1)
- Models for termination of crystal boundaries in the theory of transmission electron diffraction and comparison with experimental data (1995) (1)
- GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation (2016) (1)
- Quantification of gallium cryo-FIB milling damage in biological lamella (2023) (1)
- Decision letter: CEM500K, a large-scale heterogeneous unlabeled cellular electron microscopy image dataset for deep learning (2021) (1)
- Penicillium chrysogenum virus (PcV) capsid structure (2014) (0)
- GluN1-GluN2B NMDA receptors with exon 5 (2018) (0)
- Physical basis of amyloid fibril polymorphism (2018) (0)
- New Developments in the cisTEM Software Package (2019) (0)
- Clathrin D6 coat as full-length Triskelions (2010) (0)
- Structure and Mechanisms of Essential Complexes for Cell Survival (2008) (0)
- 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P/E tRNA (rotated conformation) (2020) (0)
- The basic challenges of biology (2005) (0)
- Symmetric reconstruction of human norovirus GII.2 Snow Mountain Virus Strain VLP in T=3 symmetry (2019) (0)
- GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION (2016) (0)
- Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry (2019) (0)
- In situ Structure RNA-Dependent (2019) (0)
- Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins (2020) (0)
- Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs, this entry contains the small ribosomal subunit, mRNA, and tRNA) (2014) (0)
- Title: Structure and assembly of calcium homeostasis modulator proteins Author List and affiliations: (2019) (0)
- Clathrin D6 coat with auxilin J-domain (2004) (0)
- Human Ndc80 Bonsai Decorated Microtubule (2010) (0)
- Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry (2019) (0)
- 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc) (2017) (0)
- Structure Ways & Means Moviesof Ice-EmbeddedParticlesEnhanceResolution in Electron Cryo-Microscopy (2012) (0)
- Editor's evaluation: Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes (2021) (0)
- Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry (2019) (0)
- Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure, 30S subunit with hybrid A/P* and P/E tRNAs, EF-G, and viomycin) (2013) (0)
- In situ single particle classification reveals distinct 60 S maturation 1 intermediates in cells 2 3 (0)
- Lambda excision HJ intermediate (2017) (0)
- An Adaptation of the Wiener Filter Suitable for Analyzing Images of Isolated Single Particles, and Accompanying 3D Reconstruction Algorithm (2011) (0)
- Structure and dynamics of clathrin coated vesicles (2006) (0)
- Electron microscopy of ultra-thin single quantum wells (1992) (0)
- Decision letter: Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit (2019) (0)
- Stoats Mating in Autumn (1937) (0)
- Core UvrA/TRCF complex (2012) (0)
- Decision letter: Visualizing formation of the active site in the mitochondrial ribosome (2021) (0)
- Bovine Papillomavirus CryoEM Image Data (2017) (0)
- VP7 recoated rotavirus DLP (2009) (0)
- 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure I) (2020) (0)
- Physical location of T1 domain in the Shaker potassium channel (2000) (0)
- 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc) (2017) (0)
- Structure of RelA bound to ribosome in presence of A/R tRNA (Structure III) (2016) (0)
- Electron cryo-microscopy of an Abeta(1-42)amyloid fibril (2015) (0)
- Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state (2017) (0)
- Structural Mechanism of F unctional Modulation by Gene Splicing in NMDA Receptors Highlights (2018) (0)
- S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II). This entry contains the large subunit ribosomal proteins. (2014) (0)
- Bovine mitochondrial ATP synthase state 1a (2015) (0)
- Decision letter: Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes (2021) (0)
- Bovine papillomavirus type 1 outer capsid (2010) (0)
- Structure and assembly of calcium homeostasis modulator proteins (2020) (0)
- S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) (2014) (0)
- Decision letter: Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity (2020) (0)
- 70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I) (2017) (0)
- User Manual for Tomography-Guided 3D Reconstruction of Subcellular Structures (TYGRESS) (2019) (0)
- From primordial clocks to circadian oscillators (2022) (0)
- Author response: Structure of the transporter associated with antigen processing trapped by herpes simplex virus (2016) (0)
- 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure II) (2017) (0)
- GluN1b-GluN2B NMDA receptor structure-Class X (2016) (0)
- 70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II) (2017) (0)
- Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter (2017) (0)
- Atomic Resolution Cryo-E M Structure of b-Galactosidase Graphical Abstract Highlights (2018) (0)
- Author response: Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction (2016) (0)
- CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE (1996) (0)
- CryoEM structure of Penicillium chrysogenum virus at 4 Å resolution (2013) (0)
- Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry (2019) (0)
- Cryo-EM structure of murine AA amyloid fibril (2019) (0)
- Exploring the Three-Dimensional Architectures of Two Families of Large Pore Channels (CALHM1,2 and Pannexin1) (2021) (0)
- 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure II) (2020) (0)
- Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids (2019) (0)
- Decision letter: Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor–ligand complex (2019) (0)
- 70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc) (2017) (0)
- Location and Identification of Macromolecular Complexes within Cellular Environments by High-Resolution Template Matching (2020) (0)
- Visualizing Single Molecule Identity and Sample Integrity in situ (2022) (0)
- Starting Actin Filaments Anew - Adenomatous Polyposis Coli Is an Actin Nucleator (2009) (0)
- Molecular Basis for Age-Dependent Acetylation by Tubulin Acetyltransferase (2015) (0)
- Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit) (2016) (0)
- Atomic model of Penicillium chrysogenum virus built from cryo-EM structure shows an ancient fold that links viral lineages. (2014) (0)
- In situ structure determination at nanometer resolution using TYGRESS (2019) (0)
- New structural insights into cap‐independent translation initiation (566.6) (2014) (0)
- Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex (2017) (0)
- Three-dimensional Reconstruction of Bovine Papillomavirus at Near-atomic Resolution by Single Particle Cryo Electron Microscopy (2009) (0)
- The detection of strain within InP-InGaAs single quantum well structures using large angle convergent beam electron diffraction (2020) (0)
- Expression and purification of two cysteine mutants of Shaker potassium channel for EM gold labeling (2001) (0)
- Cryo-EM structure of human AA amyloid fibril (2019) (0)
- Decision letter: Molecular structures of the human Slo1 K+ channel in complex with β4 (2019) (0)
- Decision letter: The complete structure of the human TFIIH core complex (2019) (0)
- Conformational changes in actin-binding proteins, revealed by single particle electron microscopy (2007) (0)
- S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II). This entry contains the small ribosomal subunit. (2014) (0)
- Insights into splicing: structure of the yeast U1 snRNP (2013) (0)
- GluN1b-GluN2B NMDA receptor in non-active-1 conformation (2016) (0)
- Electron Cryo-Microscopy of Amyloid-ß Fibrils (2010) (0)
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What Schools Are Affiliated With Nikolaus Grigorieff?
Nikolaus Grigorieff is affiliated with the following schools:
