Nikolay Dokholyan
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Physics
Nikolay Dokholyan's Degrees
- Masters Physics Moscow Institute of Physics and Technology
- Bachelors Physics Moscow Institute of Physics and Technology
Why Is Nikolay Dokholyan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nikolay V. Dokholyan is an American biophysicist, academic and researcher. He is a G. Thomas Passananti Professor and Vice Chair for Research at Penn State College of Medicine. Dokholyan’s research primarily focuses on translational research, with a particular attention on the applications of basic science in terms of addressing some of the challenging problems in biology and medicine. He is the author of a book entitled Computational Modeling of Biological Systems.
Nikolay Dokholyan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Automated minimization of steric clashes in protein structures (2011) (569)
- Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function (2008) (393)
- Small-world view of the amino acids that play a key role in protein folding. (2002) (367)
- Eris: an automated estimator of protein stability (2007) (354)
- Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis (2014) (295)
- Discrete molecular dynamics studies of the folding of a protein-like model. (1998) (287)
- Ab initio folding of proteins with all-atom discrete molecular dynamics. (2008) (282)
- Topological determinants of protein folding (2002) (276)
- Ab initio RNA folding by discrete molecular dynamics: from structure prediction to folding mechanisms. (2008) (273)
- Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis. (2021) (236)
- RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction. (2012) (235)
- iFoldRNA: three-dimensional RNA structure prediction and folding (2008) (201)
- Allostery in Its Many Disguises: From Theory to Applications. (2019) (196)
- Mechanism for the α‐helix to β‐hairpin transition (2003) (189)
- Expanding protein universe and its origin from the biological Big Bang (2002) (180)
- Molecular Dynamics Simulation of Amyloid β Dimer Formation (2004) (178)
- Engineered allosteric activation of kinases in living cells (2010) (177)
- The interface of protein structure, protein biophysics, and molecular evolution (2012) (171)
- Emergence of Protein Fold Families through Rational Design (2006) (169)
- MedusaScore: An Accurate Force Field-Based Scoring Function for Virtual Drug Screening (2008) (168)
- RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures (2015) (165)
- Discrete molecular dynamics: an efficient and versatile simulation method for fine protein characterization. (2012) (165)
- Understanding hierarchical protein evolution from first principles. (2001) (164)
- Engineering extrinsic disorder to control protein activity in living cells (2016) (163)
- Modeling backbone flexibility improves protein stability estimation. (2007) (160)
- RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. (2017) (158)
- Molecular dynamics simulation of the SH3 domain aggregation suggests a generic amyloidogenesis mechanism. (2002) (157)
- Controlling Allosteric Networks in Proteins. (2013) (156)
- The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis. (2004) (151)
- The complex molecular biology of amyotrophic lateral sclerosis (ALS). (2012) (145)
- Analysis of DNA sequences using methods of statistical physics (1998) (144)
- Identifying the protein folding nucleus using molecular dynamics. (1998) (144)
- Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation (2008) (142)
- Correctors of ΔF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein (2013) (129)
- Outcome of a workshop on applications of protein models in biomedical research. (2009) (129)
- Direct molecular dynamics observation of protein folding transition state ensemble. (2002) (121)
- Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating* (2008) (120)
- Folding Trp-cage to NMR resolution native structure using a coarse-grained protein model. (2004) (119)
- Single-molecule correlated chemical probing of RNA (2014) (118)
- Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes (2009) (118)
- Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. (2011) (115)
- Regulatory insertion removal restores maturation, stability and function of DeltaF508 CFTR. (2010) (111)
- Rational design of a ligand-controlled protein conformational switch (2013) (105)
- Multiscale modeling of nucleosome dynamics. (2007) (103)
- Molecular Origin of Polyglutamine Aggregation in Neurodegenerative Diseases (2005) (102)
- On the significance of an RNA tertiary structure prediction. (2010) (100)
- Possible mechanism for cold denaturation of proteins at high pressure. (2002) (100)
- Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences (2010) (98)
- Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants. (2006) (95)
- Discrete molecular dynamics (2012) (95)
- Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis (2015) (95)
- Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases (2010) (93)
- Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTR. (2012) (92)
- Protein folding: then and now. (2008) (92)
- Rapid Flexible Docking Using a Stochastic Rotamer Library of Ligands (2010) (86)
- Physicochemical code for quinary protein interactions in Escherichia coli (2017) (84)
- Glutathionylation at Cys-111 induces dissociation of wild type and FALS mutant SOD1 dimers. (2011) (81)
- Structural and dynamic determinants of protein-peptide recognition. (2011) (81)
- Discrete molecular dynamics simulations of peptide aggregation. (2003) (81)
- Simple but predictive protein models. (2005) (80)
- Fast complementation of split fluorescent protein triggered by DNA hybridization (2006) (79)
- Direct Observation of Protein Folding, Aggregation, and a Prion-like Conformational Conversion* (2005) (79)
- Native-like RNA tertiary structures using a sequence-encoded cleavage agent and refinement by discrete molecular dynamics. (2009) (77)
- Computational design of a PAK1 binding protein. (2010) (76)
- Three-Dimensional RNA Structure Refinement by Hydroxyl Radical Probing (2012) (75)
- Pharmacological Chaperones: Design and Development of New Therapeutic Strategies for the Treatment of Conformational Diseases. (2016) (75)
- Reconstruction of the src-SH3 protein domain transition state ensemble using multiscale molecular dynamics simulations. (2005) (74)
- Topological determinants of protein domain swapping. (2006) (73)
- Deciphering protein dynamics from NMR data using explicit structure sampling and selection. (2007) (72)
- Local unfolding of Cu, Zn superoxide dismutase monomer determines the morphology of fibrillar aggregates. (2012) (71)
- Mapping allosteric communications within individual proteins (2020) (70)
- New insights into FAK signaling and localization based on detection of a FAT domain folding intermediate. (2004) (69)
- Can contact potentials reliably predict stability of proteins? (2004) (68)
- Studies of folding and misfolding using simplified models. (2006) (68)
- The coordinated evolution of yeast proteins is constrained by functional modularity. (2006) (67)
- Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene (2017) (66)
- iFoldRNA v2: folding RNA with constraints (2015) (66)
- miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus (2018) (64)
- Correction: Emergence of Protein Fold Families through Rational Design (2006) (63)
- Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations (2017) (63)
- Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis (2018) (62)
- Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles (2012) (62)
- Structural Determinants of Skeletal Muscle Ryanodine Receptor Gating* (2013) (60)
- Folding of Cu, Zn superoxide dismutase and familial amyotrophic lateral sclerosis. (2003) (60)
- FALS mutations in Cu, Zn superoxide dismutase destabilize the dimer and increase dimer dissociation propensity: A large-scale thermodynamic analysis (2006) (59)
- Scaling behavior and structure of denatured proteins. (2005) (59)
- RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers (2020) (58)
- Functional fingerprints of folds: evidence for correlated structure-function evolution. (2003) (57)
- Thermodynamics and folding kinetics analysis of the SH3 domain form discrete molecular dynamics. (2002) (55)
- Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers (2008) (55)
- Computational design of chemogenetic and optogenetic split proteins (2018) (55)
- Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant (2011) (55)
- Fast screening of protein surfaces using geometric invariant fingerprints (2009) (54)
- BiPS, a Photocleavable, Isotopically Coded, Fluorescent Cross-linker for Structural Proteomics * (2009) (54)
- Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties. (2014) (53)
- Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR. (2008) (52)
- Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding (2008) (52)
- Imprint of evolution on protein structures. (2004) (51)
- Natural selection against protein aggregation on self-interacting and essential proteins in yeast, fly, and worm. (2008) (51)
- Structural and thermodynamic effects of post-translational modifications in mutant and wild type Cu, Zn superoxide dismutase. (2011) (51)
- Molecular dynamic simulations of cisplatin- and oxaliplatin-d(GG) intrastand cross-links reveal differences in their conformational dynamics. (2007) (51)
- A single disulfide bond differentiates aggregation pathways of beta2-microglobulin. (2005) (50)
- High-speed atomic force microscopy reveals structural dynamics of α-synuclein monomers and dimers. (2018) (50)
- Applications of Discrete Molecular Dynamics in biology and medicine. (2016) (49)
- Knowledge-based design of a biosensor to quantify localized ERK activation in living cells. (2013) (49)
- Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions (2008) (49)
- Rational coupled dynamics network manipulation rescues disease-relevant mutant cystic fibrosis transmembrane conductance regulator (2014) (48)
- Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon (2019) (48)
- Predicting oil recovery using percolation (1999) (47)
- Molecular dynamics simulation of amyloid beta dimer formation. (2004) (47)
- RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells (2018) (47)
- RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition (2018) (47)
- The path of DNA in the kinetochore (2006) (46)
- Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter* (2008) (46)
- Gaia: automated quality assessment of protein structure models (2011) (45)
- Incorporating Backbone Flexibility in MedusaDock Improves Ligand-Binding Pose Prediction in the CSAR2011 Docking Benchmark (2013) (45)
- Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS) (2014) (44)
- ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions. (2011) (44)
- Distributions of dimeric tandem repeats in non-coding and coding DNA sequences. (2000) (44)
- Conformational ensemble of native α-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations (2019) (43)
- Imaging single living cells with a scanning near-field infrared microscope based on a free electron laser (1998) (43)
- Scaling of the Distribution of Shortest Paths in Percolation (1998) (43)
- p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2 (2018) (42)
- Identification of a consensus motif in substrates bound by a Type I Hsp40 (2009) (41)
- Principles for understanding the accuracy of SHAPE-directed RNA structure modeling. (2013) (40)
- Sequence and structural determinants of Cu, Zn superoxide dismutase aggregation (2005) (40)
- Multiple folding pathways of the SH3 domain. (2003) (40)
- Cu,Zn-superoxide dismutase without Zn is folded but catalytically inactive. (2014) (39)
- Faculty Opinions recommendation of Structural and functional features of central nervous system lymphatic vessels. (2016) (39)
- The Length Dependence of the PolyQ-mediated Protein Aggregation* (2007) (39)
- Applications of statistical physics to the oil industry: predicting oil recovery using percolation theory (1999) (39)
- Dynamic Docking of Conformationally Constrained Macrocycles: Methods and Applications. (2016) (38)
- Robust and generic RNA modeling using inferred constraints: a structure for the hepatitis C virus IRES pseudoknot domain. (2010) (37)
- Hierarchy in social organization (2003) (37)
- Protein evolution within a structural space. (2003) (36)
- A Structural Model of the Pore-Forming Region of the Skeletal Muscle Ryanodine Receptor (RyR1) (2009) (36)
- MedusaDock 2.0: Efficient and Accurate Protein-Ligand Docking With Constraints (2019) (35)
- Protein Destabilization as a Common Factor in Diverse Inherited Disorders (2015) (35)
- Macromolecular crowding induces polypeptide compaction and decreases folding cooperativity. (2010) (35)
- Computational approaches to understanding protein aggregation in neurodegeneration. (2014) (35)
- Cheminformatics Meets Molecular Mechanics: A Combined Application of Knowledge-Based Pose Scoring and Physical Force Field-Based Hit Scoring Functions Improves the Accuracy of Structure-Based Virtual Screening (2012) (35)
- Light-cleavable rapamycin dimer as an optical trigger for protein dimerization. (2015) (34)
- A structural model reveals energy transduction in dynein (2006) (34)
- Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770. (2016) (34)
- Submillisecond elastic recoil reveals molecular origins of fibrin fiber mechanics. (2013) (34)
- Parallel folding pathways in the SH3 domain protein. (2007) (34)
- COMT gene locus: new functional variants (2015) (34)
- Engineering proteins for allosteric control by light or ligands (2019) (33)
- G Protein Mono-ubiquitination by the Rsp5 Ubiquitin Ligase* (2009) (33)
- iFold: a platform for interactive folding simulations of proteins (2006) (31)
- Insights into Allosteric Control of Vinculin Function from Its Large Scale Conformational Dynamics* (2006) (31)
- Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling (2015) (30)
- A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation. (2016) (30)
- Combining fluorescence detection and mass spectrometric analysis for comprehensive and quantitative analysis of redox-sensitive cysteines in native membrane proteins. (2006) (30)
- Discrete molecular dynamics distinguishes nativelike binding poses from decoys in difficult targets. (2012) (30)
- Distribution of Base Pair Repeats in Coding and Noncoding DNA Sequences (1997) (29)
- Rigid substructure search (2011) (29)
- Hybrid dynamics simulation engine for metalloproteins. (2012) (28)
- Reversible and Tunable Photoswitching of Protein Function through Genetic Encoding of Azobenzene Amino Acids in Mammalian Cells (2018) (28)
- Fidelity of the protein structure reconstruction from inter-residue proximity constraints. (2007) (27)
- Direct identification of base-paired RNA nucleotides by correlated chemical probing (2017) (27)
- Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo (2017) (27)
- Molecular Dynamics Simulation of Amyloid b Dimer Formation (2004) (27)
- Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity. (2013) (27)
- Insight into the Structure of the "Unstructured" Tau Protein. (2019) (26)
- Using protein design for homology detection and active site searches (2003) (26)
- Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability. (2013) (26)
- Structural basis for the sequence-dependent effects of platinum–DNA adducts (2009) (26)
- Structural Mechanism of S-Adenosyl Methionine Binding to Catechol O-Methyltransferase (2011) (26)
- Glassy behavior of a homopolymer from molecular dynamics simulations. (2001) (25)
- Distribution of shortest paths in percolation (1999) (25)
- Identifying importance of amino acids for protein folding from crystal structures. (2003) (25)
- Structural basis for μ-opioid receptor binding and activation. (2011) (25)
- Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers. (2015) (24)
- Energetic and structural basis for activation of the epithelial sodium channel by matriptase. (2012) (24)
- Kinetic models for the coordinated stepping of cytoplasmic dynein. (2009) (24)
- μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids (2015) (24)
- Structural complexity and functional diversity of plant NADPH oxidases (2017) (24)
- Molecular mechanisms of polypeptide aggregation in human diseases. (2007) (24)
- A Didactic Model of Macromolecular Crowding Effects on Protein Folding (2010) (23)
- A modified PATH algorithm rapidly generates transition states comparable to those found by other well established algorithms (2016) (23)
- Predicting Binding Affinity of CSAR Ligands Using Both Structure-Based and Ligand-Based Approaches (2013) (22)
- AlphaFold illuminates half of the dark human proteins. (2022) (22)
- Combined Application of Cheminformatics- and Physical Force Field-Based Scoring Functions Improves Binding Affinity Prediction for CSAR Data Sets (2011) (22)
- Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel (2018) (21)
- Intrinsic disorder mediates cooperative signal transduction in STIM1. (2014) (21)
- Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links (2011) (21)
- Probing protein aggregation using discrete molecular dynamics. (2008) (21)
- Uncertainty in oil production predicted by percolation theory (2002) (21)
- Uncertainty in oil production predicted by percolation theory (2002) (21)
- Engineering Pak1 Allosteric Switches. (2017) (20)
- DNA sequence mediates nucleosome structure and stability. (2008) (20)
- Discrete Molecular Dynamics Can Predict Helical Prestructured Motifs in Disordered Proteins (2014) (20)
- ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations (2015) (20)
- N‐terminal strands of filamin Ig domains act as a conformational switch under biological forces (2010) (20)
- MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression (2019) (19)
- A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization. (2017) (19)
- Isoform divergence of the filamin family of proteins. (2010) (19)
- Serotonin-Induced Hypersensitivity via Inhibition of Catechol O-Methyltransferase Activity (2012) (19)
- Postbreakthrough behavior in flow through porous media. (2003) (19)
- New models of Tetrahymena telomerase RNA from experimentally derived constraints and modeling. (2012) (18)
- Computational Modeling of Biological Systems (2012) (18)
- Traffic within the cytochrome b6f lipoprotein complex: gating of the quinone portal. (2014) (18)
- Rational design and implementation of a chemically inducible heterotrimerization system (2020) (17)
- Structure modeling of RNA using sparse NMR constraints (2017) (17)
- Understanding conserved amino acids in proteins (2000) (17)
- Tyrosine phosphorylation switching of a G protein (2018) (17)
- β-Methylamino-L-alanine substitution of serine in SOD1 suggests a direct role in ALS etiology (2019) (17)
- Experimentally-driven protein structure modeling. (2020) (17)
- Model of unequal chromosomal crossing over in DNA sequences 1 1 This work is supported by NIH-HGP. (1998) (17)
- Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor* (2015) (17)
- A central core disease mutation in the Ca2+ binding site of skeletal muscle ryanodine receptor impairs single channel regulation. (2019) (16)
- Regioselectivity of Catechol O-Methyltransferase Confers Enhancement of Catalytic Activity. (2011) (16)
- Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins (2019) (16)
- The architecture of the protein domain universe. (2004) (16)
- Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies (2019) (15)
- RNA tertiary structure analysis by 2'-hydroxyl molecular interference. (2014) (15)
- Discrete Molecular Dynamics Simulation of Biomolecules (2012) (15)
- The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds. (2021) (15)
- Statistical analysis of SHAPE-directed RNA secondary structure modeling. (2013) (15)
- Thermodynamic Stability of Histone H3 Is a Necessary but not Sufficient Driving Force for its Evolutionary Conservation (2011) (15)
- Homology Modeling: Generating Structural Models to Understand Protein Function and Mechanism (2012) (15)
- Using percolation theory to predict oil field performance (2002) (15)
- Recognition of platinum-DNA adducts by HMGB1a. (2012) (14)
- Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling (2021) (14)
- Drug Discovery Approaches using Quantum Machine Learning (2021) (14)
- Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX. (2015) (14)
- A physical model reveals the mechanochemistry responsible for dynein's processive motion. (2011) (14)
- Computational modeling of biological systems : from molecules to pathways (2012) (14)
- Expansion of tandem repeats and oligomer clustering in coding and noncoding DNA sequences (1999) (13)
- The N-terminal Domain Allosterically Regulates Cleavage and Activation of the Epithelial Sodium Channel* (2014) (13)
- Insights into thermophilic archaebacterial membrane stability from simplified models of lipid membranes. (2007) (13)
- Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels (2009) (13)
- Docking and Scoring with Target-Specific Pose Classifier Succeeds in Native-Like Pose Identification But Not Binding Affinity Prediction in the CSAR 2014 Benchmark Exercise (2016) (13)
- Guiding Conventional Protein-Ligand Docking Software with Convolutional Neural Networks (2020) (12)
- Redundant Functions for Nap1 and Chz1 in H2A.Z Deposition (2017) (12)
- Similarity and dissimilarity in correlations of genomic DNA (2007) (12)
- Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation (2015) (12)
- Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor (2017) (12)
- Multiscale approaches for studying energy transduction in dynein. (2009) (12)
- Pore dynamics and conductance of RyR1 transmembrane domain. (2014) (12)
- Computational methods toward accurate RNA structure prediction using coarse-grained and all-atom models. (2015) (11)
- Engineering an Allosteric Control of Protein Function. (2021) (11)
- Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors (2019) (11)
- Erratum: Correctors of dF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein (FASEB Journal (2013) 27 (536 -545) DOI:10.1096/fj.12-216119) (2014) (11)
- The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds (2020) (11)
- What is the protein design alphabet? (2004) (11)
- Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP. (2021) (11)
- The maturation of HIV‐1 protease precursor studied by discrete molecular dynamics (2014) (10)
- Two-input protein logic gate for computation in living cells (2021) (10)
- Clustering of identical oligomers in coding and noncoding DNA sequences. (1999) (10)
- Harnessing Nature’s Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins (2016) (10)
- G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca2+ (2017) (9)
- SOD1 oligomers in amyotrophic lateral sclerosis. (2021) (9)
- Intra- and Inter-Subunit Disulfide Bond Formation Is Nonessential in Adeno-Associated Viral Capsids (2012) (9)
- 8-20-2018 p 62-dependent phase separation of patient-derived KEAP 1 mutations and NRF 2 (2018) (9)
- Thermodynamically important contacts in folding of model proteins. (2000) (9)
- Computational evaluation of protein stability change upon mutations. (2010) (9)
- Various miRNAs compensate the role of miR-122 on HCV replication (2020) (9)
- Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent (2019) (9)
- Fingerprint‐based structure retrieval using electron density (2011) (9)
- GPU-Accelerated Flexible Molecular Docking. (2021) (9)
- Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator (2018) (9)
- Predicting Protein-Ligand Docking Structure with Graph Neural Network (2022) (8)
- Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling*♦ (2015) (8)
- Inter-Active Site Communication Mediated by the Dimer Interface Beta-Sheet in the Half-the-Sites Enzyme, Thymidylate Synthase. (2019) (8)
- Transmembrane helical interactions in the CFTR channel pore (2017) (8)
- The evolution dynamics of model proteins. (2004) (8)
- Toward rational vaccine engineering. (2022) (7)
- Limits in accuracy and a strategy of RNA structure prediction using experimental information (2019) (7)
- Corrigendum: Harnessing Nature’s Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins (2017) (7)
- Design and engineering of allosteric communications in proteins. (2022) (7)
- Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. (2019) (7)
- Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures. (2022) (6)
- Multiscale Modeling of RNA Structure and Dynamics (2012) (6)
- Single-channel properties of skeletal muscle ryanodine receptor pore Δ4923FF4924 in two brothers with a lethal form of fetal akinesia. (2020) (6)
- Uncovered Dynamic Coupling Resolves the Ambiguous Mechanism of Phenylalanine Hydroxylase Oxygen Binding. (2019) (6)
- Yuel: Improving the Generalizability of Structure-Free Compound-Protein Interaction Prediction (2022) (6)
- Single top quark production and Vb CKM matrix element measurement in high energy e+e− collisions (1994) (6)
- Ligand-induced disorder-to-order transitions characterized by structural proteomics and molecular dynamics simulations. (2020) (6)
- Titr-DMD-A Rapid, Coarse-Grained Quasi-All-Atom Constant pH Molecular Dynamics Framework. (2021) (5)
- Structure of prion β‐oligomers as determined by short‐distance crosslinking constraint‐guided discrete molecular dynamics simulations (2021) (5)
- Faculty Opinions recommendation of Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. (2014) (5)
- PROTEIN DESIGNABILITY AND ENGINEERING (2008) (5)
- Traveling time and traveling length for flow in porous media (1999) (5)
- Highly covarying residues have a functional role in antibody constant domains (2013) (5)
- Stabilization of μ‐opioid receptor facilitates its cellular translocation and signaling (2019) (5)
- Computational Protein Design Through Grafting and Stabilization. (2017) (5)
- Thermal Unfolding Pathway of PHD2 Catalytic Domain in Three Different PHD2 Species: Computational Approaches (2012) (4)
- Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family. (2013) (4)
- Faculty Opinions recommendation of Structure of an intermediate state in protein folding and aggregation. (2012) (4)
- Faculty of 1000 evaluation for Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy. (2018) (3)
- Identification and characterization of novel candidate compounds targeting 6‐ and 7‐transmembrane μ‐opioid receptor isoforms (2021) (3)
- Computational Modeling of Small Molecule Ligand Binding Interactions and Affinities. (2016) (3)
- Thermodynamic impacts of combinatorial mutagenesis on protein conformational stability: precise, high-throughput measurement by Thermofluor (2019) (3)
- Locking and Unlocking Thrombin Function Using Immunoquiescent Nucleic Acid Nanoparticles with Regulated Retention In Vivo. (2022) (3)
- New and Notable (1998) (3)
- Adaptation-proof SARS-CoV-2 vaccine design (2022) (3)
- Protein folding: Over half a century lasting quest: Comment on "There and back again: Two views on the protein folding puzzle" by Alexei V. Finkelstein et al. (2017) (3)
- Molecular modeling tools and approaches for CFTR and cystic fibrosis. (2011) (3)
- Scale-Free Evolution (2006) (3)
- Nanoscale programming of cellular and physiological phenotypes: inorganic meets organic programming (2021) (3)
- Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions (2022) (3)
- ASR490, a Small Molecule, Overrides Aberrant Expression of Notch1 in Colorectal Cancer (2020) (3)
- Posttranslational Modifications Promote Formation of SOD1 Oligomers With Potential Toxicity in ALS (2014) (3)
- A Folding Pathway-Dependent Score to Recognize Membrane Proteins (2011) (2)
- ApoE 4-specific misfolded intermediate identified by molecular dynamics simulations (2015) (2)
- Regulation of allosteric activation of ENaC (2014) (2)
- Monosialotetrahexosylganglioside Promotes Early Aβ42 Oligomer Formation and Maintenance. (2022) (2)
- Structural and Dynamic Insights Into α-Synuclein Dimer Conformations (2022) (2)
- A Structural Model for Vinculin Insertion into PIP 2-ContainingMembranes and the Effect of Insertion on Vinculin Activation and Localization Graphical Abstract Highlights (2017) (2)
- Yuel: Compound-Protein Interaction Prediction with High Generalizability (2021) (2)
- Erratum: ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions (Biochimica et Biophysica Acta (2011) 1808 (2954-2964)) (2012) (2)
- Differences in Conformation and Conformational Dynamics Between Cisplatin and Oxaliplatin DNA Adducts (2009) (2)
- NeuralDock: Rapid and Conformation-Agnostic Docking of Small Molecules (2021) (2)
- Modeling Mutations in Proteins Using Medusa and Discrete Molecule Dynamics (2010) (2)
- Prefusion spike protein stabilization through computational mutagenesis (2020) (2)
- Identification of novel integrin binding partners for CIB1: structural and thermodynamic basis of CIB1 promiscuity (2014) (2)
- Correction to Robust and Generic RNA Modeling Using Inferred Constraints: A Structure for the Hepatitis C Virus IRES Pseudoknot Domain (2010) (2)
- Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants (2020) (2)
- A hidden aggregation‐prone structure in the heart of hypoxia inducible factor prolyl hydroxylase (2016) (2)
- Invited: Drug Discovery Approaches using Quantum Machine Learning (2021) (2)
- Toxic SOD1 trimers are off-pathway in the formation of amyloid-like fibrils in ALS. (2022) (2)
- Toxic SOD1 trimers are off-pathway in the formation of amyloid-like fibrils in ALS (2021) (1)
- Searching for methyllysine-binding aromatic cages. (2021) (1)
- Dopamine D1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology. (2022) (1)
- Mapping co‐regulatory interactions among ligand‐binding sites in ryanodine receptor 1 (2021) (1)
- Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences. (2019) (1)
- AlphaFold Models Illuminate Half of Dark Human Proteins (2021) (1)
- Faculty Opinions recommendation of Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes. (2018) (1)
- From Disordered Amyloid β-Proteins to Soluble Oligomers and Protofibrils Using Discrete Molecular Dynamics (2013) (1)
- Scale-Free Evolution: From Proteins to Organisms (2013) (1)
- Vinculin and its Fundamental Role in Actin Bundling Formation (2018) (1)
- mRNA vaccines for cancer immunotherapy (2022) (1)
- Molecular Mechanisms of the R61T Mutation in Apolipoprotein E4: A Dynamic Rescue. (2017) (1)
- Towards Unifying Protein Evolution Theory (2007) (1)
- A molecular switch ‐ insights into allosteric control of vinculin function from in‐silico study of its large‐scale conformational dynamics (2007) (1)
- MedusaScore: An Accurate Force Field-Based Scoring Function for Virtual Drug Screening. (2008) (1)
- Applications of statistical mechanics to biological macromolecules (1999) (1)
- Faculty Opinions recommendation of De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture. (2018) (1)
- Tyrosine phosphorylation switching of a G protein substrate (2018) (1)
- Structural bioinformatics Rigid substructure search (2011) (1)
- Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene (2017) (1)
- Activating sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis. (2021) (1)
- Ryanodine Receptor Pore Structure and Function (2009) (1)
- Mutation Analysis of the Calcium Binding Site of Skeletal Muscle Ryanodine Receptor Calcium Release Channel (2019) (0)
- RNA Three-Dimensional Structure Determination Using Experimental Constraints (2013) (0)
- Faculty Opinions recommendation of Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses. (2012) (0)
- Correction to: Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants (2020) (0)
- Faculty Opinions recommendation of Inducible, reversible system for the rapid and complete degradation of proteins in mammalian cells. (2013) (0)
- New and Notable DNA Sequence Mediates Nucleosome Structure and Stability (2007) (0)
- Faculty Opinions recommendation of Principles for designing ideal protein structures. (2012) (0)
- Structural complexity and functional diversity of plant NADPH oxidases (2017) (0)
- Faculty Opinions recommendation of Anomalous diffusion, spatial coherence, and viscoelasticity from the energy landscape of human chromosomes. (2018) (0)
- Computational approachestounderstandingprotein aggregation in neurodegeneration (2014) (0)
- Structural bioinformatics iFoldRNA v 2 : folding RNA with constraints (2015) (0)
- Model for the Dynein Motor Unit (2006) (0)
- Structure of human SOD1 with T2D mutation (2016) (0)
- Structural evolution of Delta lineage of SARS-CoV-2 (2022) (0)
- Correction: Thermal Unfolding Pathway of PHD2 Catalytic Domain in Three Different PHD2 Species: Computational Approaches (2013) (0)
- Live discussion: Protein folding and neurodegeneration: biophysics to the rescue? (2004) (0)
- Urolithin A analog inhibits castration-resistant prostate cancer by targeting the androgen receptor and its variant, androgen receptor-variant 7 (2023) (0)
- Faculty Opinions recommendation of Tethered Ribozyme Ligation Enables Detection of Molecular Proximity in Homogeneous Solutions. (2020) (0)
- Faculty Opinions recommendation of Differences in the free energies between the excited states of Aβ40 and Aβ42 monomers encode their aggregation propensities. (2020) (0)
- Septins Enable T Cells Adaptive Circumnavigation and Migration-Transmigration Transition Within Structurally Complex Microenvironments (0)
- Faculty Opinions recommendation of Fluorescent peptide nanoparticles to detect amyloid-beta aggregation in cerebrospinal fluid and serum for Alzheimer’s disease diagnosis and progression monitoring. (2021) (0)
- Thermodynamic correction of F 508 del-CFTR 1 Ligand binding to a remote site thermodynamically corrects the F 508 del mutation in the human cystic fibrosis transmembrane conductance regulator (2018) (0)
- Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins (2019) (0)
- Faculty Opinions recommendation of Engineering a far-red light-activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors. (2021) (0)
- Mapping allosteric linkage to channel gating by extracellular domains in the human epithelial sodium channel (2018) (0)
- Protein Destabilization as a Common Factor in Diverse Inherited Disorders (2015) (0)
- Faculty Opinions recommendation of Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. (2021) (0)
- Mapping Co-regulation Pathways among Ligand Binding sites in RyR1 (2019) (0)
- Vitamin D3 Treatment Protects Motor Neuron Cells from Oxidative Stress and ALS-Related SOD1 Mutation (P2.062) (2015) (0)
- Faculty Opinions recommendation of Single-molecule derivation of salt dependent base-pair free energies in DNA. (2010) (0)
- Issue Information ‐ Table of Content (2018) (0)
- Theoretical model of yeast centromeric nucleosome (2006) (0)
- Corrigendum: Harnessing Nature’s Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins (2017) (0)
- W493R Gain of Function Mutation in Atypical Cystic Fibrosis Rewires the Epithelial Sodium Channel Dynamics (2015) (0)
- Faculty Opinions recommendation of Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent. (2011) (0)
- Author response for "Prefusion spike protein stabilization through computational mutagenesis" (2020) (0)
- A key amino acid in STIM1 mediates coupling to gate the Orai1 channel (2022) (0)
- Evaluation of pH change effects on the HSA folding and its drug binding characteristics, a computational biology investigation (2022) (0)
- Control of Cellular Networks by Structural Disorder (2019) (0)
- RATIONAL DESIGN OF APOE4 MUTANTS AS A TOOL FOR CELLULAR STUDIES IN ALZHEIMER’S DISEASE (2016) (0)
- Challenges and progress in research, diagnostics, and therapeutics in Alzheimer's disease and related dementias (2022) (0)
- F1000Prime recommendation of An investigation of the false discovery rate and the misinterpretation of p-values. (2016) (0)
- Faculty Opinions recommendation of Tracking protein aggregation and mislocalization in cells with flow cytometry. (2012) (0)
- Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with 5-methyl-UTP (2018) (0)
- Epithelial Sodium Channel Regulates Cleavage and Activation of the The N-terminal Domain Allosterically Molecular Biophysics (2014) (0)
- Issue Information ‐ Table of Content (2022) (0)
- Multiscale Modeling and Design of Molecular Conformational States (2010) (0)
- Whole proteome mapping of compound-protein interactions (2022) (0)
- Correction to: Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants (2020) (0)
- Generation of a Light Inhibited Src Kinase through Insertion of LOV into the Catalytic Domain (2013) (0)
- Title Cu , Zn-Superoxide Dismutase without Zn Is Folded but Catalytically Inactive Permalink (2014) (0)
- Engineering proteins for allosteric control by light or ligands (2019) (0)
- Multiscalar nucleosome dynamics in silico ‐ Role of DNA and histone tails (2007) (0)
- Theoretical model of yeast centromeric H3 histone variant CSE4 (2006) (0)
- Faculty Opinions recommendation of A fast mathematical programming procedure for simultaneous fitting of assembly components into cryoEM density maps. (2010) (0)
- Faculty Opinions recommendation of Misfolded SOD1 inclusions in patients with mutations in C9orf72 and other ALS/FTD-associated genes. (2019) (0)
- Kinetics of the protein folding transition (2001) (0)
- Designing allosteric switches of kinases (2016) (0)
- Faculty Opinions recommendation of Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease. (2021) (0)
- Faculty Opinions recommendation of Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. (2015) (0)
- Role of PIP2-Dependent Membrane Interactions in Vinculin Activation, Motility and Force Transmission (2016) (0)
- Front Cover: Reversible and Tunable Photoswitching of Protein Function through Genetic Encoding of Azobenzene Amino Acids in Mammalian Cells (ChemBioChem 20/2018) (2018) (0)
- Structure-function relationship of an unstructured protein: α-synuclein (2022) (0)
- Elucidation of the Molecular Basis and Cellular Functions of Vinculin-Actin Directional Catch Bonding (2023) (0)
- Adaptation‐Proof SARS‐CoV‐2 Vaccine Design (2022) (0)
- Faculty Opinions recommendation of Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils. (2013) (0)
- Abstract 1655: Discovery of a novel PP2A activator as a potential therapeutic for FOLFOX resistant colon cancer (2023) (0)
- Computational Modeling of Telomerase in Action (2012) (0)
- Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants (2020) (0)
- Faculty Opinions recommendation of Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. (0)
- Towards quantitative biochemistry: research and reports in biochemistry (2011) (0)
- Phenylalanine 508 forms an intra‐domain contact crucial to CFTR folding and dynamics (2009) (0)
- Faculty Opinions recommendation of Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. (2019) (0)
- Role of Ca 2+ -Mediated Signaling in ALS Pathology (2012) (0)
- Approaches for probing the sequence space of substrates recognized by molecular chaperones. (2011) (0)
- A Structural Model for Vin culin Insertion into PIP 2-ContainingMembranes and the Effect of Insertion on Vinculin Activation and Localization Graphical (2016) (0)
- Faculty Opinions recommendation of Proteostasis collapse is a driver of cell aging and death. (2019) (0)
- Simple exponential acceleration of the power iteration algorithm (2021) (0)
- Faculty Opinions recommendation of Probing allostery through DNA. (2013) (0)
- Protein‐protein interactions between CIB1 and novel integrin binding partners: structural and thermodynamic basis of CIB1 promiscuity (979.5) (2014) (0)
- Physical microscopic model of proteins under force. (2012) (0)
- GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers (2021) (0)
- Multifunctions of α‐Synuclein Explained by Its Dynamic Heterogeneous Conformations with a Hierarchy of Transition Times (2022) (0)
- Ju n 20 03 1 Folding of Cu , Zn superoxide dismutase and Familial Amyotrophic Lateral Sclerosis (2008) (0)
- Faculty Opinions recommendation of Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice. (0)
- Redundant Functions for Nap1 and Chz1 in H2A.Z Deposition (2017) (0)
- Multiscale Modeling of RNA Structure 3 and Dynamics 4 (2012) (0)
- New Models for Regulation of Vinculin by Actin and Phospholipids (2015) (0)
- Modeling the Calcium and Integrin Binding Protein 2 (2015) (0)
- Metric to distinguish closely related domain families using sequence information. (2013) (0)
- Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H 2 AX Graphical (0)
- Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain (2016) (0)
- Allosteric inactivation of an engineered optogenetic GTPase (2022) (0)
- Knowledge-Based Models (2017) (0)
- Differentiable rotamer sampling with molecular force fields (2023) (0)
- Crystal structure of photoinhibitable Intersectin1 containing C450M mutant LOV2 domain (2016) (0)
- IL-1 Via IRAK1/4 Sustains Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse (2021) (0)
- Errata (2014) (0)
- Coordinate Role of Vinculin and Metavinculin in Actin Organization (2019) (0)
- Various miRNAs are involved in efficient HCV replication (2020) (0)
- Crystal structure of C2S5: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope (2019) (0)
- Molecular Design for Research and Therapeutics (2020) (0)
- Rational design and implementation of a chemically inducible hetero-trimerization system (2020) (0)
- Light-Cleavable Rapamycin Dimer as a Universal Optical Trigger for Protein Dimerization (2015) (0)
- 5 Towards Unifying Protein Evolution Theory (2007) (0)
- Quantitative Characterization of the Interaction between Sucrose and Native Proteins via Static Light Scattering (2013) (0)
- Faculty Opinions recommendation of Structural determinants of 5-HT2B receptor activation and biased agonism. (2018) (0)
- Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain in complex with Cdc42 (2016) (0)
- Motor neuron-derived induced pluripotent stem cells as a drug screening platform for amyotrophic lateral sclerosis (2022) (0)
- Faculty Opinions recommendation of Gamma frequency entrainment attenuates amyloid load and modifies microglia. (2016) (0)
- A Coupling of Structural and Kinetic Models Reveals the Stepping Mechanics of Dynein (2010) (0)
- Chapter 9 Multiscale Modeling of RNA Structure and Dynamics (2012) (0)
- Mapping Co-regulatory Interactions among Ligand Binding sites in RyR1 (2021) (0)
- Faculty Opinions recommendation of Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. (2010) (0)
- Crystal structure of photoinhibitable Rac1 containing C450A mutant LOV2 domain (2016) (0)
- Computational design of chemogenetic and optogenetic split proteins (2018) (0)
- 147) Structural basis underlying the interaction between miRNAs and TLR8 (2017) (0)
- Crystal structure of C4S3: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope (2019) (0)
- Faculty Opinions recommendation of A blue light receptor that mediates RNA binding and translational regulation. (2019) (0)
- Editorial to "Molecular engineering of biomaterials programmed to operate in living systems". (2022) (0)
- Septin-Mediated Mechanobiological Reprogramming of T Cell Transmigration and 3D Motility (2022) (0)
- Supplemental Information A Structural Model for Vinculin Insertion into PIP 2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization (2016) (0)
- Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies (2019) (0)
- structure prediction : A CASP-like evaluation of RNA three-dimensional RNA-Puzzles (2012) (0)
- Peptidomimetics in cancer targeting (2022) (0)
- Knowledge-Based Models RNA (2017) (0)
- John von Neumann Institute for Computing Simplified Approaches to Complex Biological Systems (2008) (0)
- Deciphering the mechanistic basis for perfluoroalkyl-protein interactions. (2023) (0)
- A Robust High-Throughput Assay for Thermodynamic Correctors of the Predominant Molecular Defect Causing Cystic Fibrosis (2014) (0)
- Abstract 425: Selective ubiquitination of androgen receptor and its splice variants inhibits castration resistant prostate cancer (2022) (0)
- Is Protein Destabilization a Widespread Factor in Genetic Disease (2013) (0)
- Faculty Opinions recommendation of Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering. (2021) (0)
- Faculty Opinions recommendation of Non-proteinaceous hydrolase comprised of a phenylalanine metallo-supramolecular amyloid-like structure. (2019) (0)
- Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo (2022) (0)
- Predicting 3D RNA structure from solely the nucleotide sequence using Euclidean distance neural networks (2022) (0)
- Robust and Efficient Assessment of Potency (REAP) as a quantitative tool for dose-response curve estimation (2021) (0)
- MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression (2019) (0)
- Faculty Opinions recommendation of Allosteric Modulator Discovery: From Serendipity to Structure-Based Design. (2019) (0)
- Solution of the protein structure prediction problem at last: crucial innovations and next frontiers. (2022) (0)
- Elicitation of HIV‐specific Antibodies Targeting The Carbohydrate‐Occluded Neutralization Epitopes Through Rational Protein Design (2018) (0)
- Thermodynamics and kinetic analysis of the SH3 fold (2002) (0)
- CHAPTER 10 Scale-Free Evolution : From Proteins to Organisms (2005) (0)
- Faculty Opinions recommendation of Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. (2013) (0)
- Engineering Pak 1 Allosteric Switches (2017) (0)
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