Nikos K. Karamanos
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Nikos K. Karamanoschemistry Degrees
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(Suggest an Edit or Addition)Nikos K. Karamanos's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting (2011) (1371)
- Extracellular matrix structure. (2016) (1271)
- Glycosaminoglycans: key players in cancer cell biology and treatment (2012) (451)
- Hyaluronan–CD44 interactions as potential targets for cancer therapy (2011) (390)
- Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting (2010) (369)
- Derivatization of carbohydrates for chromatographic, electrophoretic and mass spectrometric structure analysis. (2003) (222)
- The extracellular matrix as a multitasking player in disease (2019) (214)
- Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics. (2018) (199)
- Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer (2019) (183)
- Syndecans – key regulators of cell signaling and biological functions (2017) (183)
- Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases. (2019) (171)
- Inhaled chemotherapy in lung cancer: future concept of nanomedicine (2012) (165)
- A guide to the composition and functions of the extracellular matrix (2021) (150)
- Proteoglycans remodeling in cancer: Underlying molecular mechanisms. (2017) (144)
- Recent Advances in the Structural Study of Functional Chondroitin Sulfate and Dermatan Sulfate in Health and Disease (2008) (144)
- Inhibition of breast cancer cell proliferation by style constituents of different Crocus species. (2007) (143)
- Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer. (2017) (141)
- Determination of 24 variously sulfated galactosaminoglycan- and hyaluronan-derived disaccharides by high-performance liquid chromatography. (1994) (131)
- The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology* (2012) (129)
- Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. (2015) (127)
- The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis (2009) (126)
- Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells. (2015) (123)
- Lumican, a small leucine‐rich proteoglycan (2008) (116)
- Serglycin: At the Crossroad of Inflammation and Malignancy (2014) (109)
- Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate. (1997) (101)
- Role of Receptor for Hyaluronic Acid-mediated Motility (RHAMM) in Low Molecular Weight Hyaluronan (LMWHA)-mediated Fibrosarcoma Cell Adhesion (2011) (99)
- Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors. (2005) (98)
- Serglycin Constitutively Secreted by Myeloma Plasma Cells Is a Potent Inhibitor of Bone Mineralization in Vitro* (2006) (91)
- Determination of hyaluronan and galactosaminoglycan disaccharides by high-performance capillary electrophoresis at the attomole level. Applications to analyses of tissue and cell culture proteoglycans. (1995) (91)
- The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents. (2008) (86)
- Lumican affects tumor cell functions, tumor-ECM interactions, angiogenesis and inflammatory response. (2014) (85)
- Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases. (2011) (84)
- Determination of twelve heparin‐ and heparan sulfate‐derived disaccharides as 2‐aminoacridone derivatives by capillary zone electrophoresis using ultraviolet and laser‐induced fluorescence detection (2002) (81)
- Effects of glycosaminoglycans on cell proliferation of normal osteoblasts and human osteosarcoma cells depend on their type and fine chemical compositions. (2005) (78)
- Syndecans as Modulators and Potential Pharmacological Targets in Cancer Progression (2014) (77)
- Cell–matrix interactions: focus on proteoglycan–proteinase interplay and pharmacological targeting in cancer (2014) (77)
- Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans. (2014) (74)
- Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells (2008) (72)
- Estradiol–estrogen receptor: A key interplay of the expression of syndecan‐2 and metalloproteinase‐9 in breast cancer cells (2008) (71)
- Differentiation of mesothelioma cells is influenced by the expression of proteoglycans. (2000) (71)
- Determination of iduronic acid and glucuronic acid in glycosaminoglycans after stoichiometric reduction and depolymerization using high-performance liquid chromatography and ultraviolet detection. (1988) (71)
- Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid. (2012) (70)
- Lumican regulates osteosarcoma cell adhesion by modulating TGFβ2 activity. (2011) (69)
- Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review (2012) (69)
- Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression. (2006) (68)
- High performance capillary electrophoresis method to characterize heparin and heparan sulfate disaccharides (1996) (66)
- Hyaluronan-CD44 axis orchestrates cancer stem cell functions. (2019) (66)
- Serglycin Is Implicated in the Promotion of Aggressive Phenotype of Breast Cancer Cells (2013) (65)
- Capillary electrophoresis for the quality control of chondroitin sulfates in raw materials and formulations. (2008) (65)
- Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0). (2001) (64)
- Ultrasensitive capillary electrophoresis of sulfated disaccharides in chondroitin/dermatan sulfates by laser-induced fluorescence after derivatization with 2-aminoacridone. (1999) (63)
- Structure of chondroitin sulfate. (2006) (62)
- Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules. (2016) (61)
- Shed proteoglycans in tumor stroma (2016) (60)
- Identity of dermatan and chondroitin sequences in dermatan sulfate chains determined by using fragmentation with chondroitinases and ion-pair high-performance liquid chromatography. (1995) (60)
- The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer. (2007) (59)
- The Complex Interplay Between Extracellular Matrix and Cells in Tissues. (2019) (59)
- Extracellular matrix alterations in senescent cells and their significance in tissue homeostasis. (2017) (58)
- Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism. (2009) (58)
- Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential. (2004) (57)
- The Roles of Hyaluronan/RHAMM/CD44 and Their Respective Interactions along the Insidious Pathways of Fibrosarcoma Progression (2013) (57)
- Hyaluronan and Chondroitin Sulfate Proteoglycans in the Supramolecular Organization of the Mammalian Vitreous Body (2008) (54)
- Advances in analysis of glycosaminoglycans: its application for the assessment of physiological and pathological states of connective tissues. (2002) (53)
- Imatinib inhibits colorectal cancer cell growth and suppresses stromal‐induced growth stimulation, MT1‐MMP expression and pro‐MMP2 activation (2007) (53)
- Analysis of glycosaminoglycan-derived disaccharides in biologic samples by capillary electrophoresis and protocol for sequencing glycosaminoglycans. (2002) (52)
- Human abdominal aortic aneurysm is closely associated with compositional and specific structural modifications at the glycosaminoglycan level. (1999) (51)
- Separation methods for sialic acids and critical evaluation of their biologic relevance. (2002) (50)
- Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas (2011) (49)
- Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines. (2008) (49)
- Determination and biological relevance of serum cross-linked type I collagen N-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer. (2004) (48)
- Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β (2016) (48)
- Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin‐like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells (2013) (47)
- Cell‐surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases (2013) (47)
- Imatinib as a key inhibitor of the platelet‐derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells (2013) (47)
- Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. (2019) (47)
- Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling. (2018) (46)
- Determination of N-acetyl- and N-glycolylneuraminic acids in glycoconjugates by reversed-phase high-performance liquid chromatography with ultraviolet detection (1990) (46)
- Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aorta. (2002) (46)
- The effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density. (2003) (45)
- Proteoglycans in health and disease: emerging concepts and future directions (2010) (45)
- Effects of the natural isoflavonoid genistein on growth, signaling pathways and gene expression of matrix macromolecules by breast cancer cells. (2006) (44)
- PDGF/PDGFR signaling and targeting in cancer growth and progression: Focus on tumor microenvironment and cancer-associated fibroblasts. (2014) (44)
- Proteoglycans in human malignant mesothelioma. Stimulation of their synthesis induced by epidermal, insulin and platelet-derived growth factors involves receptors with tyrosine kinase activity. (1999) (44)
- Large matrix proteoglycans, versican and perlecan, are expressed and secreted by human leukemic monocytes. (2003) (43)
- Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure–function relationship (1999) (43)
- Lumican, a small leucine‐rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes (2006) (42)
- A survey of methodological challenges for glycosaminoglycan/proteoglycan analysis and structural characterization by capillary electrophoresis (1998) (42)
- Decorin-Induced Growth Inhibition Is Overcome through Protracted Expression and Activation of Epidermal Growth Factor Receptors in Osteosarcoma Cells (2008) (42)
- Key Matrix Remodeling Enzymes: Functions and Targeting in Cancer (2021) (41)
- Metabolism and biochemical/physiological roles of chondroitin sulfates: analysis of endogenous and supplemental chondroitin sulfates in blood circulation. (2006) (41)
- An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis (2012) (40)
- Versican but not decorin accumulation is related to metastatic potential and neovascularization in testicular germ cell tumours (2006) (39)
- Analysis of neutral sugars as dinitrophenyl-hydrazones by high-performance liquid chromatography (1987) (39)
- Vectors for Inhaled Gene Therapy in Lung Cancer. Application for Nano Oncology and Safety of Bio Nanotechnology (2012) (39)
- Variations in content and structure of glycosaminoglycans of the vitreous gel from different mammalian species. (2004) (39)
- Wild blueberry (Vaccinium angustifolium) consumption affects the composition and structure of glycosaminoglycans in Sprague-Dawley rat aorta. (2006) (38)
- Imatinib Mesylate Inhibits Proliferation and Exerts an Antifibrotic Effect in Human Breast Stroma Fibroblasts (2008) (37)
- Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan. (2012) (37)
- Efficacy versus safety concerns for aerosol chemotherapy in non-small-cell lung cancer: a future dilemma for micro-oncology. (2013) (36)
- Heparan sulfate proteoglycans and heparin regulate melanoma cell functions. (2014) (36)
- The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery. (2018) (35)
- Estrogen receptor beta as epigenetic mediator of miR-10b and miR-145 in mammary cancer. (2017) (35)
- Insights into the key roles of epigenetics in matrix macromolecules-associated wound healing. (2017) (35)
- Decreased biglycan expression and differential decorin localization in human abdominal aortic aneurysms. (2002) (35)
- Glycosaminoglycans: from "cellular glue" to novel therapeutical agents. (2012) (34)
- Advances in targeting epidermal growth factor receptor signaling pathway in mammary cancer. (2018) (34)
- Identity of macromolecules present in the extracellular slime layer of Staphylococcus epidermidis. (1995) (34)
- Insight into the role of chondroitin sulfate E in angiogenesis (2019) (33)
- High-performance capillary electrophoretic analysis of hyaluronan in effusions from human malignant mesothelioma. (1997) (33)
- Inhaled chemotherapy in lung cancer: safety concerns of nanocomplexes delivered. (2012) (33)
- Tear analysis of ascorbic acid, uric acid and malondialdehyde with capillary electrophoresis. (2009) (33)
- Low molecular weight heparin inhibits melanoma cell adhesion and migration through a PKCa/JNK signaling pathway inducing actin cytoskeleton changes. (2011) (32)
- Targeting epidermal growth factor receptor in solid tumors: critical evaluation of the biological importance of therapeutic monoclonal antibodies. (2009) (32)
- Advances and advantages of nanomedicine in the pharmacological targeting of hyaluronan-CD44 interactions and signaling in cancer. (2014) (32)
- Extracellular matrix-based cancer targeting. (2021) (32)
- Identification of oligomeric domains within dermatan sulfate chains using differential enzymic treatments, derivatization with 2‐aminoacridone and capillary electrophoresis (2001) (32)
- STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells. (2004) (31)
- Chondroitin sulfate A chains enhance platelet derived growth factor-mediated signalling in fibrosarcoma cells. (2006) (31)
- Pig vitreous gel: macromolecular composition with particular reference to hyaluronan-binding proteoglycans. (2002) (31)
- Regulation of hyaluronan and versican deposition by growth factors in fibrosarcoma cell lines. (2008) (31)
- Development of an HPLC method for determining the alpha 2-adrenergic receptor agonist brimonidine in blood serum and aqueous humor of the eye. (1999) (30)
- Effects on glycosaminoglycan synthesis in cultured human mesothelioma cells of transforming, epidermal, and fibroblast growth factors and their combinations with platelet-derived growth factor. (1995) (30)
- IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules (2017) (29)
- bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells. (2009) (29)
- Parathyroid hormone (PTH) peptides through the regulation of hyaluronan metabolism affect osteosarcoma cell migration (2010) (29)
- Syndecan‐2 is a key regulator of transforming growth factor beta 2/smad2‐mediated adhesion in fibrosarcoma cells (2013) (29)
- Evaluation of modal damping factor as a diagnostic tool for osteoporosis and its relation with serum osteocalcin and collagen I N-telopeptide for monitoring the efficacy of alendronate in ovariectomized rats. (2006) (29)
- Estrogen receptor-mediated targeting of the extracellular matrix network in cancer. (2020) (28)
- Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines (2015) (28)
- A comparative biochemical analysis of glycosaminoglycans and proteoglycans in human orthotopic and heterotopic bone (2009) (28)
- Isolation, characterization and properties of the oversulphated chondroitin sulphate proteoglycan from squid skin with peculiar glycosaminoglycan sulphation pattern. (1992) (28)
- Dynamic Interplay between miRNAs and the Extracellular Matrix Influences the Tumor Microenvironment. (2019) (27)
- Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization. (2011) (27)
- Capillary electrophoresis: a tool for studying interactions of glycans/proteoglycans with growth factors. (2003) (27)
- Insights into targeting colon cancer cell fate at the level of proteoglycans / glycosaminoglycans. (2012) (27)
- Long filopodia and tunneling nanotubes define new phenotypes of breast cancer cells in 3D cultures (2020) (26)
- Isolation and characterization of matrix proteoglycans from human nasal cartilage. Compositional and structural comparison between normal and scoliotic tissues. (2002) (26)
- Syntheses, antiproliferative activity and theoretical characterization of acitretin-type retinoids with changes in the lipophilic part. (2011) (26)
- Proteoglycan synthesis induced by transforming and basic fibroblast growth factors in human malignant mesothelioma is mediated through specific receptors and the tyrosine kinase intracellular pathway. (1997) (26)
- Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker. (2005) (26)
- Expression of Syndecan-4 and Correlation with Metastatic Potential in Testicular Germ Cell Tumours (2013) (25)
- The role of oligodendrocytes in the molecular pathobiology and potential molecular treatment of cervical spondylotic myelopathy. (2010) (25)
- The Role of SLRP-Proteoglycans in Osteosarcoma Pathogenesis (2008) (25)
- Application of polyacrylamide gel electrophoresis of fluorophore-labeled saccharides for analysis of hyaluronan and chondroitin sulfate in human and animal tissues and cell cultures. (2005) (25)
- Extraction and fractionation of proteoglycans from squid skin. (1988) (25)
- Determination and distribution of N-acetyl- and N-glycolylneuraminic acids in culture media and cell-associated glycoconjugates from human malignant mesothelioma and adenocarcinoma cells. (2006) (25)
- EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules. (2014) (24)
- Profiling of the eye aqueous humor in exfoliation syndrome by high-performance liquid chromatographic analysis of hyaluronan and galactosaminoglycans. (1998) (24)
- Molecular size-dependent specificity of hyaluronan on functional properties, morphology and matrix composition of mammary cancer cells (2019) (24)
- Chondroitin sulfate prevents platelet derived growth factor‐mediated phosphorylation of PDGF‐Rβ in normal human fibroblasts severely impairing mitogenic responses (2008) (24)
- Parathyroid hormone affects the fibroblast growth factor–proteoglycan signaling axis to regulate osteosarcoma cell migration (2011) (23)
- Heparin plays a key regulatory role via a p53/FAK‐dependent signaling in melanoma cell adhesion and migration (2011) (23)
- State-of-the-art of capillary electrophoresis with application to the area of glycoconjugates. (1999) (23)
- New insights into the pathobiology of Down syndrome – hyaluronan synthase‐2 overexpression is regulated by collagen VI α2 chain (2013) (23)
- Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours. (2012) (22)
- Laser-induced fluorescence as a powerful detection tool for capillary electrophoretic analysis of heparin/heparan sulfate disaccharides. (2003) (22)
- Identification, quantification and fine structural characterization of glycosaminoglycans from uterine leiomyoma and normal myometrium. (2001) (22)
- Tumorigenic functions of serglycin: regulatory roles in epithelial to mesenchymal transition and oncogenic signaling. (2020) (22)
- Cartilage aggrecan undergoes significant compositional and structural alterations during laryngeal cancer. (2006) (22)
- Glycosaminoglycans from two human malignant mesothelioma cell lines: determination, distribution, and effect of platelet-derived growth factor on their synthesis. (1995) (22)
- Strategies for analysis and structure characterization of glycans/proteoglycans by capillary electrophoresis. Their diagnostic and biopharmaceutical importance. (1999) (21)
- Isolation and chemical study of the glycosaminoglycans from squid cornea. (1991) (21)
- IGF-I/EGF and E2 signaling crosstalk through IGF-IR conduit point affects breast cancer cell adhesion. (2016) (21)
- Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma. (2015) (20)
- Preparation and Toxicological Assessment of Functionalized Carbon Nanotube-Polymer Hybrids (2014) (20)
- Epigenetic Alterations in Triple-Negative Breast Cancer—The Critical Role of Extracellular Matrix (2021) (20)
- Design, synthesis, and evaluation of the antiproliferative activity of a series of novel fused xanthenone aminoderivatives in human breast cancer cells. (2007) (20)
- In vitro effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by estrogen receptor-positive and -negative human breast cancer epithelial cells. (2002) (20)
- Synthesis and distribution of glycosaminoglycans in human leukemic B- and T-cells and monocytes studied using specific enzymic treatments and high-performance liquid chromatography. (2001) (20)
- Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells. (2007) (19)
- Assessment of PCBs exposure in human hair using double focusing high resolution mass spectrometry and single quadrupole mass spectrometry. (2012) (19)
- Screening of N-acylneuraminic acids in serum and tissue specimens of mouse C57BI with Lewis' lung cancer by high-performance liquid chromatography. (1998) (19)
- High performance capillary electrophoresis as a powerful analytical tool of glycoconjugates (1999) (19)
- Analysis of carbendazim and thiabendazole in lemons by CE-DAD (2003) (18)
- Heparin—A unique stimulator of human colon cancer cells' growth (2008) (18)
- Redox N-Alkylation of Tosyl Protected Amino Acid and Peptide Esters. (1994) (18)
- Two squid skin proteoglycans each containing chondroitin sulfates with different sulfation patterns. (1992) (18)
- Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates (2015) (18)
- Complexity of matrix phenotypes (2020) (17)
- Capillary electrophoresis: a superior miniaturized tool for analysis of the mono-, di-, and oligosaccharide constituents of glycan moieties in proteoglycans (2001) (17)
- Extracellular matrix: key structural and functional meshwork in health and disease (2019) (17)
- Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules. (2012) (16)
- Purification and characterisation of a minor low-sulphated dermatan sulphate-proteoglycan from ray skin. (1999) (16)
- Arabino-Galactan Proteins from Pistacia lentiscus var. chia: isolation, characterization and biological function (2008) (16)
- Dynamic interplay between breast cancer cells and normal endothelium mediates the expression of matrix macromolecules, proteasome activity and functional properties of endothelial cells. (2014) (16)
- miR-200b restrains EMT and aggressiveness and regulates matrix composition depending on ER status and signaling in mammary cancer (2020) (15)
- Importance of high-performance liquid chromatographic analysis of serum N-acylneuraminic acids in evaluating surgical treatment in patients with early endometrial cancer. (1999) (15)
- Expression and distribution of N-acetyl and N-glycolylneuraminic acids in secreted and cell-associated glycoconjugates by two human osteosarcoma cell lines. (2007) (15)
- Alteration in serum leptin correlates with alterations in serum N-telopeptide of collagen type I and serum osteocalcin during the progression of osteoporosis in ovariectomized rats (2005) (14)
- The Solubility of SnO2 in NaF--AlF3--Al2O3 Melts. (1995) (14)
- Wild blueberry (V. angustifolium)-enriched diets alter aortic glycosaminoglycan profile in the spontaneously hypertensive rat. (2012) (14)
- Could growth factor-mediated extracellular matrix deposition and degradation offer the ground for directed pharmacological targeting in fibrosarcoma? (2013) (14)
- Study of the glycosaminoglycans from squid skin (1986) (14)
- Inhibition of receptor tyrosine kinase-based signal transduction as specific target for cancer treatment. (2002) (14)
- Regulatory roles of hyaluronan in health and disease (2011) (13)
- The differential proliferative response of fetal and adult human skin fibroblasts to TGF-β is retained when cultured in the presence of fibronectin or collagen. (2014) (13)
- 1.1 Extracellular matrix: a functional scaffold (2012) (13)
- GnRH analogues containing conformationally restricted amino acids in positions 3 and 6: differential impact on pituitary binding affinity and direct antiproliferative effect on breast cancer cells† (2008) (13)
- Extracellular Matrix: Pathobiology and Signaling (2012) (13)
- Signal transduction by IL-2 and its receptors as target in treatment of rheumatoid arthritis. (2005) (12)
- Versican undergoes specific alterations in the fine molecular structure and organization in human aneurysmal abdominal aortas. (2003) (12)
- FACE Analysis as a Fast and Reliable Methodology to Monitor the Sulfation and Total Amount of Chondroitin Sulfate in Biological Samples of Clinical Importance (2014) (12)
- Metalloproteinases in health and disease: challenges and the future prospects (2011) (12)
- Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells (2020) (12)
- Disaccharide composition in glycosaminoglycans/proteoglycans analyzed by capillary zone electrophoresis. (2001) (12)
- Protein tyrosine kinase and estrogen receptor-dependent pathways regulate the synthesis and distribution of glycosaminoglycans/proteoglycans produced by two human colon cancer cell lines. (2007) (12)
- Analysis of Carcinogenic Heterocyclic Amines by High Performance Liquid Chromatography (1996) (11)
- Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease. (2013) (11)
- Proteoglycans: Biological Roles and Strategies for Isolation and Determination of Their Glycan Constituents (2000) (11)
- Microemulsion electrokinetic capillary chromatography of sulfated disaccharides derived from glycosaminoglycans (2001) (11)
- EMMPRIN/CD147-encriched membrane vesicles released from malignant human testicular germ cells increase MMP production through tumor-stroma interaction. (2014) (11)
- Effect of insulin and epidermal growth factors on the synthesis of glycosaminoglycans/proteoglycans in cultured human malignant mesothelioma cells of different phenotypic morphology (1996) (11)
- Design, synthesis and cell growth inhibitory activity of a series of novel aminosubstituted xantheno[1,2-d]imidazoles in breast cancer cells. (2008) (11)
- Vibrational bone characteristics versus bone density for the assessment of osteoporosis in ovariectomized rats (2010) (11)
- A capillary zone electrophoresis method for determining N-acetylneuraminic acid in glycoproteins and blood sera. (2002) (11)
- Structure analysis of lipoglycans and lipoglycan-derived carbohydrates by capillary electrophoresis and mass spectrometry. (2002) (11)
- Isolation and chemical characterization of two acid carbohydrates from the sea urchin shell, extraction and fractionation of their protein complexes (1991) (11)
- Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential (2020) (11)
- Determination of the HNK-1 epitope (3-sulphated glucuronic acid) in intact chondroitin sulphates by ELISA. Application to squid skin proteoglycans and their oversulphated carbohydrate structures. (1994) (11)
- Anti-TNFα treatment decreases the previously increased serum Indian Hedgehog levels in patients with ankylosing spondylitis and affects the expression of functional Hedgehog pathway target genes. (2015) (10)
- A Method to Quantitate Total Sialic Acid, Glucosamine, and Galactosamine in Blood Serum and Glycoconjugates by HPLC (1998) (10)
- IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and -independent pathways. (2004) (10)
- Dietary manganese affects the concentration, composition and sulfation pattern of heparan sulfate glycosaminoglycans in Sprague-Dawley rat aorta (2006) (10)
- Monitoring serum chondroitin sulfate levels in patients submitted to coronary artery bypass surgery. (2011) (10)
- Pathophysiology and pharmacological targeting of tumor-induced bone disease: current status and emerging therapeutic interventions. (2011) (10)
- Isolation and characterisation of a small dermatan sulphate proteoglycan from ray skin (Raja clavata) (1999) (10)
- Antibodies to three chondroitin sulfate-containing proteoglycans in squid skin recognize hexa- or longer chondroitin oligosaccharides as major antigenic determinants. (1995) (9)
- Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor. (2003) (9)
- Increased β‐glucuronidase activity in bronchoalveolar lavage fluid of children with bacterial lung infection: A case–control study (2015) (9)
- Chemistry of Niobium Chlorides in the CsCl--NaCl Eutectic Melt. 2. Voltammetric Studies of Niobium Chlorides and Oxochlorides in the CsCl--NaCl Eutectic Melt. (1995) (9)
- Isolation and high-performance liquid chromatographic analysis of ray (Raja clavata) skin glycosaminoglycans (1991) (9)
- Identification of the commonest cystic fibrosis transmembrane regulator gene DeltaF508 mutation: evaluation of PCR--single-strand conformational polymorphism and polyacrylamide gel electrophoresis. (2006) (8)
- In vitro and in vivo antiresorptive effects of bisphosphonates in metastatic bone disease. (2005) (8)
- Hyaluronan Determination: Biological Significance & Analytical Tools (2007) (8)
- Analysis of N-acetyl and N-glycolylneuraminic acid in rat serum and tissues with Walker 256 carcinoma by high-performance liquid chromatography. (1999) (8)
- Special Issue: Proteoglycans: signaling, targeting and therapeutics (2013) (8)
- Potent antiproliferative activity of bradykinin B2 receptor selective agonist FR-190997 and analogue structures thereof: A paradox resolved? (2020) (8)
- Enhanced antitumour activity of cyclopendadienyl-substituted metallocene dihalides in human breast and colon cancer cells. (2009) (8)
- The action of hyaluronan in functional properties, morphology and expression of matrix effectors in mammary cancer cells depends on its molecular size (2020) (8)
- Matrix pathobiology—central roles for proteoglycans and heparanase in health and disease (2017) (8)
- High-Performance Liquid Chromatographic Determination of Xylitole and Hexosaminitols Present in the Reduced Terminal of Glycosaminoglycans (1993) (7)
- Small Tyrosine Kinase Inhibitors as Key Molecules in the Expression of Metalloproteinases by Solid Tumors (2008) (7)
- Synthesis and antiproliferative activity of two diastereomeric lignan amides serving as dimeric caffeic acid-l-DOPA hybrids. (2016) (7)
- Gonadotropin-releasing hormone analogues alter gene expression of metalloproteinases and their tissue inhibitors in human breast cancer epithelial cells. (2006) (7)
- The Effect of Synbiotics on Acute Radiation-Induced Diarrhea and Its Association with Mucosal Inflammatory and Adaptive Responses in Rats (2013) (7)
- DETERMINATION OF PHOSPHORYLATED AND SULFATED LINKAGE–REGION OLIGOSACCHARIDES IN CHONDROITIN/DERMATAN AND HEPARAN SULFATE PROTEOGLYCANS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (1999) (7)
- Presence of the HNK-1 epitope (3-sulfoglucuronic acid) on oligosaccharides from squid skin chondroitin proteoglycans and degradation of proteoglycans by proteolytic enzymes. (1991) (7)
- Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer (2014) (7)
- Isolation, biochemical and immunological characterisation of two sea urchin glycoproteins bearing sulphated poly(sialic acid) polysaccharides rich in N-glycolyl neuraminic acid. (1996) (6)
- Isolation and analysis of a novel acidic polysaccharide from the case of squid pen. (1999) (6)
- The Secreted Protein C10orf118 Is a New Regulator of Hyaluronan Synthesis Involved in Tumour-Stroma Cross-Talk (2021) (6)
- The presence of a novel extracellular hyaluronidase in squid cranial cartilage. (2004) (6)
- 8.2 Targeting the tumor microenvironment in cancer progression (2012) (6)
- Facile preparation of the 1-Hydroxybenzotriazolyl ester of A/-Tritylpyroglutamic acid and its application to the synthesis of TRH, [D-His2]TRH and analogues incorporating c/s-And trans-4-hydroxy-L-proline (1995) (6)
- 8.9 Delivery systems targeting cancer at the level of ECM (2012) (5)
- Effects of mitogens on synthesis and distribution of heparan and chondroitin sulphates by human leukemic B, T cells and monocytes studied by high-performance liquid chromatography and radiochemical detection. (2001) (5)
- ΕGFR/ERβ-Mediated Cell Morphology and Invasion Capacity Are Associated with Matrix Culture Substrates in Breast Cancer (2020) (5)
- Methodological Challenges of Protein Analysis in Blood Serum and Cerebrospinal Fluid by Capillary Electrophoresis (2003) (5)
- Identification of κ and λ chains of the major immunoglobulin G subclasses by capillary zone electrophoresis (2002) (5)
- Prolonged survival and time to disease progression with zoledronic acid in patients with bone metastases from non-small cell lung cancer. (2010) (5)
- Glycosaminoglycan in cerebrum, cerebellum and brainstem of young sheep brain with particular reference to compositional and structural variations of chondroitin-dermatan sulfate and hyaluronan. (2008) (5)
- Adherence of Staphylococcus epidermidis to human endothelial cells is associated with a polysaccharidic component of its extracellular mucous layer (2011) (4)
- Synthesis and Biological Evaluation of New GnRH Analogues on Pituitary and Breast Cancer Cells (2007) (4)
- Altered Adipokine Expression in Tumor Microenvironment Promotes Development of Triple Negative Breast Cancer (2022) (4)
- Synthesis and expression of mRNA encoding for different versican splice variants is related to the aggregation of human epithelial mesothelioma cells. (2002) (4)
- Glycosylation of proteins: specificity, biological role, and analysis of glycan moieties. (1998) (4)
- Exosomes and the Extracellular Matrix: a dynamic interplay in cancer progression. (2021) (4)
- The microRNA-cell surface proteoglycan axis in cancer progression. (2022) (4)
- Chapter 22 Capillary electrophoresis of intact and depolymerized glycosaminoglycans and proteoglycans (2002) (4)
- State of the Art of Biochemical Markers in Metastatic Bone Disease and the Role of Bisphosphonates as Therapeutic Agents (2005) (4)
- Sulfated Hyaluronan Modulates the Functional Properties and Matrix Effectors Expression of Breast Cancer Cells with Different Estrogen Receptor Status (2021) (3)
- Fast screening of glycosaminoglycan disaccharides by fluorophore-assisted carbohydrate electrophoresis (FACE): applications to biologic samples and pharmaceutical formulations. (2015) (3)
- Special issue: Translating Extracellular Matrix: from Cancer Progression to Therapeutics. (2020) (3)
- Novel insights into matrix pathobiology regulatory mechanisms in health and disease (2014) (3)
- Faculty of 1000 evaluation for Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease. (2018) (3)
- Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through β-catenin/MDR1 signaling to sustain chemoresistance (2022) (3)
- Infectious crystalline keratopathy and endophthalmitis caused by a slime producing Staphylococcus epidermidis strain (2004) (3)
- Crocetin alters the gene expression pattern of metalloproteinases and their inhibitors in breast cancer cells MDA-MB-231 (2008) (3)
- Tuning the Spin-Crossover Behaviour in Fe(II) Polymeric Composites for Food Packaging Applications (2022) (3)
- Rapid Assay for the Determination of Two Photoactivatible Kainic Acid Analogues by High-Performance Liquid Chromatography (1994) (2)
- Screening of Cerebrospinal Fluid and Blood Sera of Multiple Sclerosis Patients for Oligoclonal Immunoglobulins by Capillary Electrophoresis (2003) (2)
- Matrix-mediated cell behaviour and properties. (2014) (2)
- Zarogouldis, P., et al., Vectors for Inhaled Gene Therapy in Lung Cancer. Application for Nano Oncology and Safety of Bio Nanotechnology. Int. J. Mol. Sci. 2012, 13, 10828–10862 (2012) (2)
- A Theoretical Investigation of the Electronic Structure and Spectrum for S3 (1995) (2)
- Development of Environmentally Friendly Biocidal Coatings Based on Water-soluble Copolymers for Air-cleaning Filters (2022) (2)
- A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis. (2011) (2)
- Investigation on Toxicity and Teratogenicity in Rats of a Retinoid-Polyamine Conjugate with Potent Anti-Inflammatory Properties. (2016) (2)
- Recreating the extracellular matrix: novel 3D cell culture platforms in cancer research. (2023) (2)
- Trends in extracellular matrix biology (2022) (2)
- CRYSTAL STRUCTURE OF DIETHYL 1,2,3,4-TETRATHIEPANE-6,6-DICARBOXYLATE AND STRUCTURAL ASPECTS OF S4-CONTAINING RING SYSTEMS (1994) (1)
- 3.P.276 Sulfation patterns of chondroitin sulfate and dermatan sulfate as key factors for atherosclerotic aortic abdominal aneurysm (1997) (1)
- EGF/EGFR signaling axis is a significant regulator of the proteasome expression and activity in colon cancer cells (2014) (1)
- 8.5 Pharmacological targeting of proteoglycans and metalloproteinases: an emerging aspect in cancer treatment (2012) (1)
- Validated capillary electrophoretic assays for disaccharide composition analysis of galactosaminoglycans in biologic samples and drugs/nutraceuticals. (2015) (1)
- Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates (2014) (1)
- Interplay Between Chemotherapy-Activated Cancer Associated Fibroblasts and Cancer Initiating Cells Expressing CD44v6 Promotes Colon Cancer Resistance (2022) (1)
- Principles and applications of capillary electrophoresis and microchips in forensic and clinical toxicology (2008) (1)
- Hyaluronan as “Agent Smith” in cancer extracellular matrix pathobiology: Regulatory roles in immune response, cancer progression and targeting (2022) (1)
- New Analogs of Polyamine Toxins from Spiders and Wasps: Liquid Phase Fragment Synthesis and Evaluation of Antiproliferative Activity (2022) (1)
- An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis (2012) (1)
- Matrix Effectors and Cancer (2021) (1)
- Data on the putative role of p53 in breast cancer cell adhesion: Technical information for adhesion assay (2016) (1)
- Faculty Opinions recommendation of Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families. (2019) (0)
- Faculty Opinions recommendation of Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis. (2020) (0)
- Extracellular Matrix Perturbation in Down Syndrome Pathology (2012) (0)
- Enhancement of mesenchymal stem cells' chondrogenic potential by type II collagen-based bioscaffolds. (2023) (0)
- Epidermal growth factor/epidermal growth factor receptor signaling axis is a significant regulator of the proteasome expression and activity in colon cancer cells (2014) (0)
- Evaluating the Effects of MicroRNAs on Proteoglycans and Matrix Constituents' Expression and Functional Properties. (2023) (0)
- List of contributing authors (2012) (0)
- Faculty Opinions recommendation of A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix. (2019) (0)
- Faculty of 1000 evaluation for Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium. (2018) (0)
- Staphylococcus epidermidis Attachment to Human Endothelial Cells is Mediated Through Its 20-kDa PS (2008) (0)
- Intact and oligomeric glycosaminoglycans analyzed with capillary electrophoresis. (2001) (0)
- Studying the Effects of Glycosaminoglycans in Cell Morphological Aspect with Scanning Electron Microscopy. (2023) (0)
- Faculty Opinions recommendation of CD44-dependent inflammation, fibrogenesis, and collagenolysis regulates extracellular matrix remodeling and tensile strength during cutaneous wound healing. (2018) (0)
- Application of capillary electrophoresis in the analysis of novel synthetic dideoxynucleoside analogues with potential anti-HIV activity. (2001) (0)
- Editorial: Molecules of the extracellular matrix as cancer targets (2022) (0)
- Corrigendum to “Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma” [Cell. Signal. 27(10) (2015) 2054–2067] (2015) (0)
- 3.P.285 Atherosclerotic abdominal aortic aneurysm is associated with specific quantitative changes of glycosaminoglycans (1997) (0)
- 8.1 Introduction (2012) (0)
- Faculty Opinions recommendation of Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma. (2020) (0)
- Preparation and Properties of Enantiomerically Pure Nα‐Tritylamino Acid Fluorides. (1999) (0)
- Faculty Opinions recommendation of Soluble syndecans: biomarkers for diseases and therapeutic options. (2018) (0)
- Extracellular matrix - an emerging research area in biosciences (2022) (0)
- Identification of kappa and lambda chains of the major immunoglobulin G subclasses by capillary zone electrophoresis. (2002) (0)
- Faculty Opinions recommendation of MicroRNA as Crucial Regulators of Gene Expression in Estradiol-Treated Human Endothelial Cells. (2018) (0)
- P113 A BIOCHEMICAL APPROACH FOR ANALYZING CHONDROITIN SULPHATE IN BLOOD CIRCULATION AND PURITY TESTING IN SUPPLEMENTS AND DRUGS (2006) (0)
- Extracellular matrix: The dynamic structural and functional network in health and disease (2022) (0)
- The Role of Exosomes in Epithelial–to-Mesenchymal Transition and Cell Functional Properties in Head and Neck Cancer (2023) (0)
- Metalloproteinases as key molecules to target invasiveness in solid tumors (2009) (0)
- Faculty Opinions recommendation of Intravital three-dimensional bioprinting. (2020) (0)
- Dietary blueberries affect the composition of extracellular matrix in rat aorta (2005) (0)
- pH-Sensitive Gold Nanorods for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Delivery and DNA-Binding Studies (2023) (0)
- Shed proteoglycans in tumor stroma (2016) (0)
- The Biological Role of Chondroitin Sulfate Proteoglycans in Cancer (2009) (0)
- Faculty Opinions recommendation of Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration. (2020) (0)
- Estrogen receptors as regulators of syndecan‐4 expression in solid tumors (2010) (0)
- ESR2 Drives Mesenchymal-to-Epithelial Transition in Triple-Negative Breast Cancer and Tumorigenesis In Vivo (2022) (0)
- Proteoglycans in abdominal aortic aneurysm: Quantitative and histochemical alterations in the extracellular matrix versican (1999) (0)
- Faculty Opinions recommendation of MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. (2020) (0)
- Biochemistry and molecular biology in Greece: History and perspectives (2008) (0)
- Abbreviations and acronyms used (2012) (0)
- Editor Profile: Nikos Karamanos (2021) (0)
- Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer (2014) (0)
- About the Editor/Section Editors (2012) (0)
- Wild Blueberry (V. angustifolium) Consumption Alters the Composition and Structure of Glycosaminoglycans (GAGs) in Spontaneously Hypertensive Rats (SHR) (2009) (0)
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What Schools Are Affiliated With Nikos K. Karamanos?
Nikos K. Karamanos is affiliated with the following schools:
