Nilesh Samani

Q: What Schools Are Affiliated With Nilesh Samani

Nilesh Samani is affiliated with the following schools: University of Groningen, University of Cambridge, Harvard University, University of Oslo, University of Leicester, University of Lübeck, Boston University, University of Leeds, University of Bristol, University of Oxford, University of Dundee, Technical University of Munich, University of Lausanne, Aarhus University

Nilesh Samani's AcademicInfluence.com Rankings

Nilesh Samani

Philosophy

#4569

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#7136

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#2563

World Rank

#3575

Historical Rank

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Philosophy

Nilesh Samani's Degrees

Masters Medicine University of Leicester
Doctorate Cardiology University of Leicester

Why Is Nilesh Samani Influential?

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According to Wikipedia, Sir Nilesh Jayantilal Samani is a British physician who is professor of Cardiology at the University of Leicester, consultant cardiologist at Glenfield Hospital in the city, and Medical Director of the British Heart Foundation.

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Nilesh Samani's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
Genomewide association analysis of coronary artery disease. (2007) (2067)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (2009) (1735)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
Common variants near MC4R are associated with fat mass, weight and risk of obesity (2008) (1307)
New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
Genome-wide association study identifies eight loci associated with blood pressure (2009) (1225)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Genome-wide association study identifies 74 loci associated with educational attainment (2016) (1114)
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants (2009) (1100)
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke (2004) (960)
Human metabolic individuality in biomedical and pharmaceutical research (2011) (929)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Genome-wide association analysis identifies 20 loci that influence adult height (2008) (816)
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility (2011) (807)
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. (2014) (799)
Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
Identification of seven loci affecting mean telomere length and their association with disease (2013) (761)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries (2018) (735)
Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior (2010) (688)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
DNA methylation and body-mass index: a genome-wide analysis (2014) (664)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies (2012) (646)
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease (2011) (638)
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies (2010) (631)
Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (2009) (617)
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. (2009) (614)
Meta-analysis and imputation refines the association of 15q25 with smoking quantity (2010) (605)
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (600)
White Cell Telomere Length and Risk of Premature Myocardial Infarction (2003) (597)
Telomere shortening in atherosclerosis (2001) (596)
Mendelian randomization of blood lipids for coronary heart disease (2014) (580)
Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study (2007) (579)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data (2011) (556)
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity (2012) (555)
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium (2009) (551)
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (516)
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region (2009) (513)
Rare and low-frequency coding variants alter human adult height (2016) (511)
New susceptibility locus for coronary artery disease on chromosome 3q22.3 (2009) (510)
The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits (2012) (506)
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies (2011) (490)
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease (2009) (484)
Association analyses based on false discovery rate implicate new loci for coronary artery disease (2017) (476)
Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (465)
A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. (1996) (464)
The transcriptional landscape of age in human peripheral blood (2015) (450)
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. (2008) (450)
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease (2016) (434)
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (428)
Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (2011) (424)
New gene functions in megakaryopoiesis and platelet formation (2011) (423)
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (421)
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes (2010) (421)
Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease (2010) (417)
Bayesian refinement of association signals for 14 loci in 3 common diseases (2012) (416)
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease (2008) (410)
A structural variation reference for medical and population genetics (2020) (394)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors (2020) (379)
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect (2013) (375)
MicroRNAs in cardiovascular disease: an introduction for clinicians (2015) (370)
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits (2013) (365)
Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults (2018) (359)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction (2010) (345)
SLC2A9 Is a High-Capacity Urate Transporter in Humans (2008) (334)
High rates of non-adherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry (HP LC-MS/MS) urine analysis (2014) (333)
Common variants near TERC are associated with mean telomere length (2010) (318)
Sequence variants at CHRNB 3 – CHRNA 6 and CYP 2 A 6 affect smoking behavior (2010) (312)
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (309)
Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants (2014) (303)
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study (2017) (302)
The impact of low-frequency and rare variants on lipid levels (2015) (300)
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders (2013) (299)
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk (2010) (290)
Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure: a prospective European study (2017) (288)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure (2020) (288)
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation (2014) (287)
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension (2010) (285)
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation (2015) (285)
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease (2012) (283)
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling (2009) (266)
Genetic loci influencing kidney function and chronic kidney disease (2010) (266)
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (2014) (260)
Mapping of a major locus that determines telomere length in humans. (2005) (256)
Genomic prediction of coronary heart disease (2016) (241)
Whole-genome sequencing of patients with rare diseases in a national health system (2020) (239)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age (2014) (238)
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
Dysfunctional nitric oxide signalling increases risk of myocardial infarction (2013) (234)
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (2016) (234)
Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms (2017) (224)
Genetically determined height and coronary artery disease. (2015) (220)
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism. (2015) (216)
Genome-wide mapping of human loci for essential hypertension (2003) (214)
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci (2016) (214)
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (2017) (204)
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations (2009) (201)
Genetic evidence of assortative mating in humans (2017) (199)
The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis (2013) (199)
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference (2016) (198)
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (2009) (195)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome (2012) (191)
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury (2011) (190)
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease (2014) (187)
A multi-centre randomised controlled trial of minimally invasive direct coronary bypass grafting versus percutaneous transluminal coronary angioplasty with stenting for proximal stenosis of the left anterior descending coronary artery. (2004) (186)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias (2012) (180)
Left atrial radiofrequency ablation during mitral valve surgery for continuous atrial fibrillation: a randomized controlled trial. (2005) (177)
Blood pressure loci identified with a gene-centric array. (2011) (177)
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. (2011) (177)
Development and validation of multivariable models to predict mortality and hospitalization in patients with heart failure (2017) (175)
Plasma matrix metalloproteinase-9 and left ventricular remodelling after acute myocardial infarction in man: a prospective cohort study. (2007) (168)
Mendelian randomization studies in coronary artery disease. (2014) (168)
Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction. (2018) (167)
Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. (2016) (164)
A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels (2009) (164)
Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase (2012) (163)
Large Scale Association Analysis of Novel Genetic Loci for Coronary Artery Disease (2009) (163)
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. (2013) (160)
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. (2012) (158)
A systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: rationale, design, and baseline characteristics of BIOSTAT‐CHF (2016) (157)
Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease. (2010) (155)
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk (2014) (155)
Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study (2008) (154)
Telomere length loss due to smoking and metabolic traits (2014) (153)
Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease (2010) (151)
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study. (2004) (148)
A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease (2013) (148)
Association of WNK1 Gene Polymorphisms and Haplotypes With Ambulatory Blood Pressure in the General Population (2005) (147)
Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction (2014) (147)
Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
Directional dominance on stature and cognition in diverse human populations (2015) (144)
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. (2009) (143)
A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease (2011) (141)
Common Variants in Genes Underlying Monogenic Hypertension and Hypotension and Blood Pressure in the General Population (2008) (136)
Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease (2017) (135)
Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci (2017) (135)
Early narrowed afferent arteriole is a contributor to the development of hypertension. (1994) (135)
Risk Factors for Nonadherence to Antihypertensive Treatment (2017) (135)
Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans (2011) (134)
Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. (2016) (134)
A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF) Family Heart Study. (2005) (134)
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease (2013) (133)
Biological ageing and cardiovascular disease (2008) (132)
A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex (2012) (131)
Dimorphism in the P2Y1 ADP Receptor Gene Is Associated With Increased Platelet Activation Response to ADP (2004) (131)
Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats (1993) (130)
The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
Plasma tissue inhibitor of metalloproteinase-1 and matrix metalloproteinase-9: novel indicators of left ventricular remodelling and prognosis after acute myocardial infarction. (2008) (129)
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. (2015) (128)
The clinical significance of interleukin‐6 in heart failure: results from the BIOSTAT‐CHF study (2019) (128)
Novel Platelet Membrane Glycoprotein VI Dimorphism Is a Risk Factor for Myocardial Infarction (2001) (125)
Beyond "misunderstanding": written information and decisions about taking part in a genetic epidemiology study. (2007) (125)
A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. (2009) (124)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney (2017) (121)
A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. (2003) (120)
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages (2016) (119)
Reproducibility of Telomere Length Assessment - An International Collaborative Study (2015) (116)
Galectin-1 interacts with β-1 subunit of integrin (2003) (115)
Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study (2019) (115)
Genetic analysis of thermolabile methylenetetrahydrofolate reductase as a risk factor for myocardial infarction. (1996) (114)
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. (2005) (112)
Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts (2012) (108)
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. (2016) (108)
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection. (2019) (106)
Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array (2009) (106)
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
Non-cardiac comorbidities in heart failure with reduced, mid-range and preserved ejection fraction. (2018) (105)
Biochemical Screening for Nonadherence Is Associated With Blood Pressure Reduction and Improvement in Adherence (2017) (104)
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration (2011) (104)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
Genetics of myocardial infarction: a progress report. (2010) (103)
Telomere length in circulating leukocytes is associated with lung function and disease (2013) (103)
Elevated C-reactive protein in atherosclerosis--chicken or egg? (2008) (102)
The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol (2008) (100)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (2018) (100)
Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia (2013) (98)
Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. (2010) (98)
52 Genetic Loci Influencing Myocardial Mass. (2016) (98)
Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis (2007) (97)
The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts (2009) (95)
Heritability of Early Repolarization: A Population-Based Study (2011) (95)
Expression of the renin gene in extra-renal tissues of the rat. (1988) (95)
Physiological Interaction Between &agr;-Adducin and WNK1-NEDD4L Pathways on Sodium-Related Blood Pressure Regulation (2008) (94)
Longer Leukocyte Telomeres Are Associated with Ultra-Endurance Exercise Independent of Cardiovascular Risk Factors (2013) (94)
Transcutaneous ultrasound measurement of blood-flow in internal mammary artery to coronary artery grafts (1992) (94)
A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure. (1993) (93)
Coronary Artery Disease–Associated Locus on Chromosome 9p21 and Early Markers of Atherosclerosis (2008) (93)
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (93)
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers (2014) (92)
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm. (2013) (92)
Whole genome sequencing of a sporadic primary immunodeficiency cohort (2018) (92)
Hepatic Metabolism and Transporter Gene Variants Enhance Response to Rosuvastatin in Patients With Acute Myocardial Infarction: The GEOSTAT-1 Study (2010) (90)
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2019) (90)
Transcript expression-aware annotation improves rare variant interpretation (2020) (89)
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. (2010) (89)
Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry (2009) (88)
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci (2015) (88)
Genome-wide association meta-analyses combining multiple risk phenotypes provides insights into the genetic architecture of cutaneous melanoma susceptibility (2020) (87)
Significant association of cagA positiveHelicobacter pylori strains with risk of premature myocardial infarction (2000) (87)
Evaluating drug targets through human loss-of-function genetic variation (2019) (86)
Angiotensinogen Gene Promoter Region Variant Modifies Body Size–Ambulatory Blood Pressure Relations in Hypertension (2002) (82)
Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol (2011) (82)
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. (2012) (82)
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. (2016) (81)
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. (2012) (81)
Determinants and functional significance of myocardial perfusion reserve in severe aortic stenosis. (2012) (81)
Circulating Stromelysin‐1 (MMP‐3): A novel predictor of LV dysfunction, remodelling and all‐cause mortality after acute myocardial infarction (2008) (81)
Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of restenosis after coronary angioplasty (1995) (80)
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. (2013) (80)
Genome scans for hypertension and blood pressure regulation. (2003) (80)
Analysis of quantitative trait loci for blood pressure on rat chromosomes 2 and 13. Age-related differences in effect. (1996) (80)
Helicobacter pylori seropositivity in subjects with acute myocardial infarction. (1996) (80)
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals (2022) (80)
A Variant in LDLR Is Associated With Abdominal Aortic Aneurysm (2013) (79)
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat (2016) (79)
Association Between the Coronary Artery Disease Risk Locus on Chromosome 9p21.3 and Abdominal Aortic Aneurysm (2008) (79)
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk (2015) (79)
Waist‐to‐hip ratio and mortality in heart failure (2018) (79)
Polygenic basis and biomedical consequences of telomere length variation (2021) (79)
Secretory Phospholipase A2-IIA and Cardiovascular Disease (2013) (78)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2019) (78)
Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1. (2017) (77)
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. (2017) (77)
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. (2019) (77)
Genetic Architecture of Ambulatory Blood Pressure in the General Population: Insights From Cardiovascular Gene-Centric Array (2010) (77)
Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT‐CHF (2017) (77)
A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length (2009) (76)
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis (2017) (75)
Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk (2013) (75)
Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN (2019) (74)
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length (2020) (74)
Association analysis of β2 adrenoceptor polymorphisms with hypertension in a Black African population (2000) (73)
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation (2015) (72)
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci (2019) (72)
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. (2013) (72)
The GPIa C807T dimorphism associated with platelet collagen receptor density is not a risk factor for myocardial infarction (1999) (71)
Influence of noninvasive peripheral arterial blood pressure measurements on assessment of dynamic cerebral autoregulation. (2007) (70)
Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling (2018) (70)
Glycoprotein IIIa polymorphism and risk of myocardial infarction. (1997) (70)
Genetic Dissection of Region Around the Sa Gene on Rat Chromosome 1: Evidence for Multiple Loci Affecting Blood Pressure (2001) (70)
Leukocyte telomere length and coronary artery calcification. (2010) (70)
Prospective analysis of the association of infection with CagA bearing strains of Helicobacter pylori and coronary heart disease (2002) (69)
Telomere Length in Newborns is Related to Maternal Stress During Pregnancy (2017) (69)
DNA fingerprinting of spontaneously hypertensive and Wistar-Kyoto rats: implications for hypertension research. (1989) (69)
The effect of LRRK2 loss-of-function variants in humans (2020) (69)
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease (2015) (68)
Cystatin C and Cardiovascular Disease (2016) (68)
Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies (2009) (67)
A regulatory SNP of the BICD1 gene contributes to telomere length variation in humans. (2008) (67)
Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells (2020) (67)
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
Exon repetition in mRNA. (1999) (66)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (65)
Improving clinical trials for cardiovascular diseases: a position paper from the Cardiovascular Round Table of the European Society of Cardiology. (2016) (65)
Association with outcomes and response to treatment of trimethylamine N‐oxide in heart failure: results from BIOSTAT‐CHF (2018) (65)
The Relationship Between Plasma Angiopoietin-like Protein 4 Levels, Angiopoietin-like Protein 4 Genotype, and Coronary Heart Disease Risk (2010) (65)
A saturated map of common genetic variants associated with human height (2022) (65)
Reproducibility of telomere length assessment: an international collaborative study (2014) (64)
Genetic analysis for a shared biological basis between migraine and coronary artery disease (2015) (64)
Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease (2017) (64)
Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains. (1998) (64)
Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study (2017) (63)
Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (62)
Selenium and outcome in heart failure (2019) (62)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (61)
Dissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses (2015) (61)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (61)
Galectin-1 interacts with beta-1 subunit of integrin. (2003) (61)
Posttraumatic Stress Disorder and Not Depression Is Associated with Shorter Leukocyte Telomere Length: Findings from 3,000 Participants in the Population-Based KORA F4 Study (2013) (60)
DCAF4, a novel gene associated with leucocyte telomere length (2015) (60)
Expression of the plasminogen activator system in the human vascular wall. (2000) (60)
Telomere biology in heart failure (2008) (60)
Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses (2021) (60)
Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations. (2008) (59)
Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (59)
Male-Specific Region of the Y Chromosome and Cardiovascular Risk: Phylogenetic Analysis and Gene Expression Studies (2013) (58)
Telomere length and outcome in heart failure. (2010) (58)
Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis (2017) (58)
Potassium and the use of renin–angiotensin–aldosterone system inhibitors in heart failure with reduced ejection fraction: data from BIOSTAT‐CHF (2018) (58)
Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues (2014) (58)
Spontaneous Coronary Artery Dissection: Pathophysiological Insights From Optical Coherence Tomography. (2019) (58)
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders (2019) (57)
Psychological morbidity and illness appraisals of patients with cardiac and non-cardiac chest pain attending a rapid access chest pain clinic: a longitudinal cohort study (2007) (57)
Telomere length and psychological well-being in patients with chronic heart failure. (2010) (57)
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension. (2006) (57)
Socioeconomic status and telomere length: the West of Scotland Coronary Prevention Study (2009) (56)
Genome-Wide Haplotype Analysis of Cis Expression Quantitative Trait Loci in Monocytes (2013) (56)
Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia (2016) (54)
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. (2016) (54)
Resistance to activated protein C and risk of premature myocardial infarction (1994) (54)
Bio‐adrenomedullin as a marker of congestion in patients with new‐onset and worsening heart failure (2019) (54)
Association between left ventricular mass and telomere length in a population study. (2010) (54)
Effect of Bile Acid Sequestrants on the Risk of Cardiovascular Events: A Mendelian Randomization Analysis (2015) (54)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
Short telomere length is associated with impaired cognitive performance in European ancestry cohorts (2017) (53)
Kidney renin mRNA levels in the early and chronic phases of two‐kidney, one clip hypertension in the rat (1989) (52)
The personal genome—the future of personalised medicine? (2010) (52)
Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion (2009) (52)
New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals (2017) (50)
Adult height and risk of 50 diseases: a combined epidemiological and genetic analysis (2018) (50)
A widespread abnormality of renin gene expression in the spontaneously hypertensive rat: modulation in some tissues with the development of hypertension. (1989) (50)
A major structural abnormality in the renin gene of the spontaneously hypertensive rat. (1989) (49)
Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. (2018) (49)
Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk (2012) (49)
Distribution of Tissue Plasminogen Activator Insertion/Deletion Polymorphism in Myocardial Infarction and Control Subjects (1998) (48)
Characterization of the clinical and immunological phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. (2020) (48)
Short leukocyte telomere length is associated with abdominal aortic aneurysm (AAA). (2010) (48)
Possible association between telomere length and renal dysfunction in patients with chronic heart failure. (2008) (48)
Signatures of miR-181a on the Renal Transcriptome and Blood Pressure (2015) (47)
Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease (2019) (46)
A miR-327–FGF10–FGFR2-mediated autocrine signaling mechanism controls white fat browning (2017) (46)
A genome-wide survey demonstrates widespread non-linear mRNA in expressed sequences from multiple species (2005) (46)
HSP27 locus cosegregates with left ventricular mass independently of blood pressure. (1996) (46)
Effect of healthy lifestyle behaviors on the association between leukocyte telomere length and coronary artery calcium. (2010) (46)
High blood pressure and metabolic disorders are associated in the Lyon hypertensive rat (1993) (46)
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits (2018) (46)
Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction (2018) (46)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants (2021) (45)
The effect of preoperative atrial fibrillation on survival following mitral valve repair for degenerative mitral regurgitation. (2007) (45)
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use (2019) (45)
Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation (2008) (45)
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors. (2016) (45)
Chromosome 9p21 and cardiovascular disease: the story unfolds. (2008) (45)
Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction (2021) (44)
Genetic Dissection of a Blood Pressure Quantitative Trait Locus on Rat Chromosome 1 and Gene Expression Analysis Identifies SPON1 As a Novel Candidate Hypertension Gene (2007) (44)
Detection of Renin Messenger RNA in Rat Tissues: Increased Sensitivity Using an RNAse Protection Technique (1987) (44)
Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease (2015) (44)
Large-Scale Candidate Gene Analysis of HDL Particle Features (2011) (43)
Association of shorter telomeres with coronary artery disease in Indian subjects (2008) (43)
ms1, a novel stress‐responsive, muscle‐specific gene that is up‐regulated in the early stages of pressure overload‐induced left ventricular hypertrophy (2002) (43)
Circulating Leukocyte and Carotid Atherosclerotic Plaque Telomere Length: Interrelation, Association With Plaque Characteristics, and Restenosis After Endarterectomy (2011) (42)
A Common Variant in Low-Density Lipoprotein Receptor–Related Protein 6 Gene (LRP6) Is Associated With LDL-Cholesterol (2009) (42)
Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases. (2019) (42)
Circulating microRNAs and hypertension--from new insights into blood pressure regulation to biomarkers of cardiovascular risk. (2016) (42)
Concentric vs. eccentric remodelling in heart failure with reduced ejection fraction: clinical characteristics, pathophysiology and response to treatment (2019) (41)
A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist. (1997) (41)
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions (2017) (41)
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney (2020) (41)
Leukocyte telomere length and marital status among middle-aged adults. (2011) (41)
Analysis of promoter region polymorphism in the aldosterone synthase gene (CYP11B2) as a risk factor for myocardial infarction. (2000) (41)
Genome-Wide Association Study Identifies Variants in Casein Kinase II (CSNK2A2) to be Associated With Leukocyte Telomere Length in a Punjabi Sikh Diabetic Cohort (2014) (41)
Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets (2018) (41)
T594M variant of the epithelial sodium channel beta-subunit gene and hypertension in individuals of African ancestry in South Africa. (2003) (40)
The Prothrombin 20210A Allele and Its Association with Myocardial Infarction (1999) (40)
Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the British Genetics of Hypertension Study (2006) (40)
Magnetic resonance perfusion imaging in patients with coronary artery disease: a qualitative approach (2002) (40)
Sorting out cholesterol and coronary artery disease. (2010) (40)
Analysis of the role of angiotensinogen in spontaneous hypertension. (1995) (39)
Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension. (2003) (39)
Galectin 1 inhibits incorporation of vitronectin and chondroitin sulfate B into the extracellular matrix of human vascular smooth muscle cells. (2003) (39)
Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution (2009) (39)
Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of and prognosis after myocardial infarction. (1996) (39)
Biomarker-Guided Versus Guideline-Based Treatment of Patients With Heart Failure: Results From BIOSTAT-CHF. (2018) (39)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2019) (38)
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (37)
Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics (2019) (37)
Polymorphic Variation in the 11β-Hydroxylase Gene Associates With Reduced 11-Hydroxylase Efficiency (2007) (37)
Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype (2014) (37)
Association between anthropometric obesity measures and coronary artery disease: a cross-sectional survey of 16 657 subjects from 444 Polish cities (2009) (37)
Coronary Artery Disease–Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes (2017) (36)
Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression (2012) (36)
The PCSK9-LDL Receptor Axis and Outcomes in Heart Failure: BIOSTAT-CHF Subanalysis. (2017) (36)
Differential regulation of ventricular adrenomedullin and atrial natriuretic peptide gene expression in pressure and volume overload in the rat. (1998) (35)
Novel endotypes in heart failure: effects on guideline-directed medical therapy (2018) (35)
Continuous estimates of dynamic cerebral autoregulation: influence of non-invasive arterial blood pressure measurements (2008) (35)
Polymorphisms in Catechol-O-Methyltransferase Modify Treatment Effects of Aspirin on Risk of Cardiovascular Disease (2014) (34)
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (34)
Genetic associations with lipoprotein subfractions provide information on their biological nature. (2012) (34)
Coronary Artery Disease-Related Genetic Variant on Chromosome 10q11 Is Associated With Carotid Intima-Media Thickness and Atherosclerosis (2010) (34)
Association between lipid profile and circulating concentrations of estrogens in young men. (2009) (34)
Exon repetition: a major pathway for processing mRNA of some genes is allele-specific. (2004) (33)
The interleukin-10-1082 'A' allele and abdominal aortic aneurysms. (2007) (33)
Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking (2013) (33)
Circadian clock genes cause activation of the human PAI‐1 gene promoter with 4G/5G allelic preference (2006) (33)
A Novel Surface Electrocardiogram–Based Marker of Ventricular Arrhythmia Risk in Patients With Ischemic Cardiomyopathy (2012) (33)
Analysis of the postulated interaction between the angiotensin II sub-type 1 receptor gene A1166C polymorphism and the insertion/deletion polymorphism of the angiotensin converting enzyme gene on risk of myocardial infarction. (2001) (33)
Common Variation in the WNK1 Gene and Blood Pressure in Childhood: The Avon Longitudinal Study of Parents and Children (2008) (33)
Four Genetic Loci Influencing Electrocardiographic Indices of Left Ventricular Hypertrophy (2011) (32)
Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease (2013) (32)
Complementary intron sequence motifs associated with human exon repetition: a role for intragenic, inter-transcript interactions in gene expression (2007) (32)
Increased expression of the SA gene in the kidney of the spontaneously hypertensive rat is localized to the proximal tubule (1994) (32)
Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages. (2015) (32)
VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish (2015) (32)
Large-Scale Analysis of Determinants, Stability, and Heritability of High-Density Lipoprotein Cholesterol Efflux Capacity (2017) (32)
Genome-wide meta-analysis of common variant differences between men and women (2012) (31)
The Prevalence and Significance of the Early Repolarization Pattern in Sudden Arrhythmic Death Syndrome Families (2016) (31)
Renal dysfunction is associated with shorter telomere length in heart failure (2009) (31)
JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells (2018) (30)
SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells (2018) (30)
Pathway analysis shows association between FGFBP1 and hypertension. (2011) (29)
Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension (2013) (29)
Prospective evaluation of two novel ECG-based restitution biomarkers for prediction of sudden cardiac death risk in ischaemic cardiomyopathy (2014) (29)
Metabolomics profiling reveals novel markers for leukocyte telomere length (2016) (29)
Systematic Review of Studies That Have Evaluated Screening Tests in Relatives of Patients Affected by Nonsyndromic Thoracic Aortic Disease (2018) (29)
Does the type of prosthesis influence early left ventricular mass regression after aortic valve replacement? Assessment with magnetic resonance imaging. (2003) (29)
Discovery of novel heart rate-associated loci using the Exome Chip (2017) (29)
The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure (2019) (28)
Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension. (2006) (28)
The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1. (2019) (28)
Rationale and design of the PRognostic Importance of MIcrovascular Dysfunction in asymptomatic patients with Aortic Stenosis (PRIMID-AS): a multicentre observational study with blinded investigations (2013) (28)
Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis (2009) (28)
Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study (2006) (28)
Phenotypic consequences of variation across the aldosterone synthase and 11‐beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study (2007) (28)
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. (2019) (28)
Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin (2006) (27)
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. (2014) (27)
Whole Genome Survey of Copy Number Variation in the Spontaneously Hypertensive Rat: Relationship to Quantitative Trait Loci, Gene Expression, and Blood Pressure (2010) (27)
Kozak sequence polymorphism in the platelet GPIbalpha gene is not associated with risk of myocardial infarction. (2000) (27)
Mitral valve repair for active culture positive infective endocarditis (2005) (27)
Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure. (2015) (27)
Transcutaneous ultrasound assessment of internal thoracic artery to coronary artery grafts in patients with and without ischaemic symptoms. (1994) (27)
The −1185 A/G and −1051 G/A dimorphisms in the von Willebrand factor gene promoter and risk of myocardial infarction (2001) (26)
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. (2015) (26)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits (2019) (26)
Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention (2018) (26)
QALYs in cost-effectiveness analysis: an overview for cardiologists (2015) (25)
A flexible and parallelizable approach to genome‐wide polygenic risk scores (2019) (25)
The 9p21 locus does not affect risk of coronary artery disease through induction of type 1 interferons. (2013) (25)
Influence of a Coronary Artery Disease–Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior (2018) (25)
Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA2)-V Isoenzyme in Coronary Heart Disease: Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels (2014) (25)
Proteomic diversity of high‐density lipoprotein explains its association with clinical outcome in patients with heart failure (2018) (25)
Hypertension in the spontaneously hypertensive rat and the sex chromosomes. (1994) (25)
Chronic infarct size after spontaneous coronary artery dissection: implications for pathophysiology and clinical management (2020) (25)
No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis (2016) (25)
Variations in captopril formulations used to treat children with heart failure: a survey in the United kingdom (2007) (24)
Endocrine vasculatures are preferable targets of an antitumor ineffective low dose of anti-VEGF therapy (2016) (24)
FGF21 signalling pathway and metabolic traits – genetic association analysis (2010) (24)
Evidence for genetic regulation of endothelial progenitor cells and their role as biological markers of atherosclerotic susceptibility. (2008) (24)
Genetically modulated educational attainment and coronary disease risk. (2019) (24)
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney (2021) (24)
Leukocyte Telomere Length in Young Adults Born Preterm: Support for Accelerated Biological Ageing (2015) (24)
Images in cardiovascular medicine. Lipomatous metaplasia in ischemic cardiomyopathy: a common but unappreciated entity. (2007) (24)
Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets (2019) (24)
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study (2010) (24)
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals (2018) (24)
Geographical location affects the levels and association of trimethylamine N‐oxide with heart failure mortality in BIOSTAT‐CHF: a post‐hoc analysis (2019) (24)
Coronary heart disease in people of south-Asian origin (2004) (23)
Anaemia is associated with shorter leucocyte telomere length in patients with chronic heart failure (2010) (23)
Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank (2021) (23)
Mapping of genetic loci predisposing to hypertriglyceridaemia in the hereditary hypertriglyceridaemic rat: analysis of genetic association with related traits of the insulin resistance syndrome (2003) (23)
Impact of Selection Bias on Estimation of Subsequent Event Risk (2017) (23)
FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease–Associated Genetic Variant and Influences Monocyte Transendothelial Migration (2020) (23)
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants (2014) (23)
Measurement and initial characterization of leukocyte telomere length in 474,074 participants in UK Biobank (2022) (23)
Evaluation of the uptake and delivery of the NHS Health Check programme in England, using primary care data from 9.5 million people: a cross-sectional study (2020) (23)
A simple and efficient method for the isolation of differentially expressed genes. (1998) (22)
LGALS2 functional variant rs7291467 is not associated with susceptibility to myocardial infarction in Caucasians. (2007) (22)
HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis (2019) (22)
Arachidonate 5-lipoxygenase (5-LO) promoter genotype and risk of myocardial infarction: a case-control study. (2008) (22)
STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway (2012) (22)
Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes. (2008) (22)
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. (2019) (22)
Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles (2016) (22)
Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis (2019) (22)
Efficacy of transmyocardial laser revascularization and thoracic sympathectomy for the treatment of refractory angina. (2004) (21)
Resuscitated cardiac arrest and prognosis following myocardial infarction (2014) (21)
Switching harmful visceral fat to beneficial energy combustion improves metabolic dysfunctions (2017) (21)
DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes (2018) (21)
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events (2019) (21)
Tumour biomarkers: association with heart failure outcomes (2020) (21)
Enrichment of Rare Variants in Loeys-Dietz Syndrome Genes in Spontaneous Coronary Artery Dissection but Not in Severe Fibromuscular Dysplasia. (2020) (21)
Clinical correlates and outcome associated with changes in 6‐minute walking distance in patients with heart failure: findings from the BIOSTAT‐CHF study (2019) (21)
Short- and medium-term survival following coronary artery bypass surgery in British Indo-Asian and white Caucasian individuals: impact of diabetes mellitus. (2010) (21)
Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction (2012) (21)
Cerebral critical closing pressure estimation from Finapres and arterial blood pressure measurements in the aorta (2006) (21)
Genome Wide Association Studies: Identifying the Genes that Determine the Risk of Abdominal Aortic Aneurysm (2008) (21)
A major population resource of 474,074 participants in UK Biobank to investigate determinants and biomedical consequences of leukocyte telomere length. (2021) (20)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
A network analysis to identify pathophysiological pathways distinguishing ischaemic from non‐ischaemic heart failure (2020) (20)
Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms (2016) (20)
Low Birth Weight in MZ Twins Discordant for Birth Weight is Associated with Shorter Telomere Length and lower IQ, but not Anxiety/Depression in Later Life (2015) (20)
The Impact of Power Output During Percutaneous Catheter Radiofrequency Ablation for Atrial Fibrillation on Efficacy and Safety Outcomes: A Systematic Review (2013) (20)
Failure of the heat-shock protein 70 locus to cosegregate with blood pressure in spontaneously hypertensive rat x Wistar—Kyoto rat cross (1993) (20)
Kidney Specificity of Rat Chromosome 1 Blood Pressure Quantitative Trait Locus Region (2002) (19)
Impact of mitral regurgitation in patients with worsening heart failure: insights from BIOSTAT‐CHF (2021) (19)
Cardiac Expression of ms1/STARS, a Novel Gene Involved in Cardiac Development and Disease, Is Regulated by GATA4 (2012) (19)
Neutrophil‐to‐lymphocyte ratio and outcomes in patients with new‐onset or worsening heart failure with reduced and preserved ejection fraction (2021) (19)
The Epithelial Sodium Channel &ggr;-Subunit Gene and Blood Pressure: Family Based Association, Renal Gene Expression, and Physiological Analyses (2011) (19)
Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte Stress 1 gene promoter (2008) (19)
Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction (2007) (19)
Coronary artery disease predisposing haplogroup I of the Y chromosome, aggression and sex steroids--genetic association analysis. (2014) (19)
Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques (2018) (19)
Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure. (2019) (18)
Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits (2016) (18)
Modulation of mouse renin gene expression by dietary sodium chloride intake in one-gene, two-gene and transgenic animals. (1989) (18)
Major cardiovascular risk factors in Lyon hypertensive rats. A correlation analysis in a segregating population (1996) (18)
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval (2018) (18)
Chromosome 1 blood pressure QTL region influences renal function curve and salt sensitivity in SHR. (2002) (18)
Common Variation in the WNK 1 Gene and Blood Pressure in Childhood The Avon Longitudinal Study of Parents and Children (2008) (18)
Renal and extra-renal levels of renin mRNA in experimental hypertension. (1991) (18)
Correction: Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (2017) (18)
Inverse associations between androgens and renal function: the Young Men Cardiovascular Association (YMCA) study. (2009) (18)
Can low risk cardiac patients be 'fast tracked' to Phase IV community exercise schemes for cardiac rehabilitation? A randomised controlled trial. (2011) (18)
Corrigendum to "Reproducibility of Telomere Length Assessment - An International Collaborative Study" [International Journal of Epidemiology 2014, doi: 10.1093/ije/dyu191] (2015) (17)
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential (2022) (17)
Risks and benefits of percutaneous coronary intervention in spontaneous coronary artery dissection (2021) (17)
Molecular biology of the vascular renin-angiotensin system. (1991) (17)
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension (2007) (17)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
The Story Unfolds (2008) (17)
Analysis with the exome array identifies multiple new independent variants in lipid loci. (2016) (17)
Chromosomal assignment of the human SA gene to 16p13.11 and demonstration of its expression in the kidney. (1994) (17)
The role of cathepsin D in the pathophysiology of heart failure and its potentially beneficial properties: a translational approach (2019) (17)
Genetic Assessment of Potential Long-Term On-Target Side Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibitors (2019) (17)
Analysis of the renin gene intron A tandem repeat region of Milan and Lyon hypertensive rat strains. (1990) (17)
Effect of a common X-linked angiotensin II type 2-receptor gene polymorphism (-1332 G/A) on the occurrence of premature myocardial infarction and stenotic atherosclerosis requiring revascularization. (2007) (17)
Expanding the concept of telomere dysfunction in cardiovascular disease. (2008) (16)
Coronary angiography in worsening heart failure: determinants, findings and prognostic implications (2017) (16)
Secretory Phospholipase A2-IIA and Cardiovascular Disease A Mendelian Randomization Study (2017) (16)
Left ventricular weight but not blood pressure is associated with sex chromosomes in Lyon rats (1996) (16)
Enhanced linkage of a locus on chromosome 2 to premature coronary artery disease in the absence of hypercholesterolemia (2007) (16)
Quality of life in men and women with heart failure: association with outcome, and comparison between the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5 dimensions questionnaire (2021) (16)
The physical health challenges in patients with severe mental illness: cardiovascular and metabolic risks (2010) (16)
Spontaneous Coronary Artery Dissection (2020) (16)
Leukotriene B4 production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with a risk of myocardial infarction. (2007) (15)
Higher doses of loop diuretics limit uptitration of angiotensin-converting enzyme inhibitors in patients with heart failure and reduced ejection fraction (2020) (15)
Transient drifts between Finapres and continuous intra-aortic measurements of blood pressure (2007) (15)
Apolipoprotein E polymorphism does not predict risk of restenosis after coronary angioplasty. (1996) (15)
A Clinical Tool to Predict Low Serum Selenium in Patients with Worsening Heart Failure (2020) (15)
The rat SA gene shows genotype-dependent tissue-specific expression. (1994) (15)
The SA gene: predisposition to hypertension and renal function in man. (1995) (15)
Endomyocardial fibrosis associated with antiphospholipid syndrome (2000) (15)
Determinants of day–night difference in blood pressure, a comparison with determinants of daytime and night-time blood pressure (2016) (15)
Erratum: Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2017) (14)
A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors (2017) (14)
Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis (2020) (14)
Diurnal variation in excitation-contraction coupling is lost in the adult spontaneously hypertensive rat heart (2013) (14)
A common biological basis of obesity and nicotine addiction (2019) (14)
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention (2022) (14)
Urotensin-II System in Genetic Control of Blood Pressure and Renal Function (2013) (14)
The Relation of Rapid Changes in Obesity Measures to Lipid Profile - Insights from a Nationwide Metabolic Health Survey in 444 Polish Cities (2014) (14)
Subsequent Event Risk in Individuals With Established Coronary Heart Disease (2019) (14)
Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF (2020) (13)
Spontaneous Coronary Artery Dissection Insights on Rare Genetic Variation From Genome Sequencing (2020) (13)
Heart failure treatment up‐titration and outcome and age: an analysis of BIOSTAT‐CHF (2020) (13)
Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia (2020) (13)
Vascular histopathology and connective tissue ultrastructure in spontaneous coronary artery dissection: pathophysiological and clinical implications (2021) (13)
A structural and functional dissection of the cardiac stress response factor MS1 (2011) (13)
Is there an association between angiotensin converting enzyme (ACE) genotypes and abdominal aortic aneurysm? (2010) (13)
Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. (2011) (13)
Daily remote ischaemic conditioning following acute myocardial infarction: a randomised controlled trial (2018) (13)
Integration of Genetics into a Systems Model of Electrocardiographic Traits Using HumanCVD BeadChip (2012) (13)
Localisation and physiological effects of tissue renin-angiotensin systems. (1989) (12)
Analysis of the Role of the SA Gene in Blood Pressure Regulation by Gene Targeting (2003) (12)
Tissue expression of components of the renin-angiotensin system in experimental post-infarction heart failure in rats: effects of heart failure and angiotensin-converting enzyme inhibitor treatment. (1997) (12)
Genetic analysis of the SA and Na+/K+‐ATPase α1 genes in the Milan hypertensive rat (1998) (12)
Genetic Analysis of Leukocyte Type-I Interferon Production and Risk of Coronary Artery Disease (2015) (12)
Assessment of liquid captopril formulations used in children (2010) (12)
Geographical differences in heart failure characteristics and treatment across Europe: results from the BIOSTAT-CHF study (2020) (12)
Genetic Associations With Plasma Angiotensin Converting Enzyme 2 Concentration (2020) (11)
Genetic Insights Into Bicuspid Aortic Valve Disease (2017) (11)
Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease (2020) (11)
Non‐adherence to heart failure medications predicts clinical outcomes: assessment in a single spot urine sample by liquid chromatography‐tandem mass spectrometry (results of a prospective multicentre study) (2021) (11)
Mapping of genetic determinants of the sympathoneural response to stress. (2005) (11)
Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease. (2020) (11)
Molecular genetics of coronary artery disease: measuring the phenotype. (1998) (11)
Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation (2019) (11)
Molecular genetics of susceptibility to the development of hypertension. (1994) (11)
ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression (2012) (10)
Statin treatment: can genetics sharpen the focus? (2015) (10)
The Coronary Artery Disease-associated Coding Variant in Zinc Finger C3HC-type Containing 1 (ZC3HC1) Affects Cell Cycle Regulation* (2016) (10)
KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern (2019) (10)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
Genetic variants associated with celiac disease and the risk for coronary artery disease (2015) (10)
Analysis of Gene-Gene Interactions among Common Variants in Candidate Cardiovascular Genes in Coronary Artery Disease (2015) (10)
Modifiable traits, healthy behaviours, and leukocyte telomere length: a population-based study in UK Biobank (2022) (10)
When should we diagnose incomplete right bundle branch block? (1993) (10)
The canonical E-box motif: a target for glucocorticoid action that drives rhythmic mouse Pai-1 transcription in vitro. (2008) (10)
Molecular biology of the renin cascade in hypertension Report of a Meeting of Physicians and Scientists, University of Leicester (1994) (9)
Vascular RAA system. (1993) (9)
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
New developments in renin and hypertension. (1991) (9)
Cardiovascular events and mortality in people with and without type 2 diabetes: An observational study in a contemporary multi‐ethnic population (2020) (9)
Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation (2017) (9)
Analysis of phenotypic consequences of renin gene polymorphism in Lyon rats (1997) (9)
Lack of association of genetic variants in the LRP8 gene with familial and sporadic myocardial infarction (2008) (9)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci (2020) (9)
Telomere length and outcome in heart failure (2008) (9)
Images in cardiology. Endomyocardial fibrosis associated with antiphospholipid syndrome. (2000) (9)
Novel loss of function mutation in NOTCH1 in a family with bicuspid aortic valve, ventricular septal defect, thoracic aortic aneurysm, and aortic valve stenosis (2020) (9)
Effects of size at birth, childhood growth patterns and growth hormone treatment on leukocyte telomere length (2017) (9)
Prevalence and Disease Spectrum of Extracoronary Arterial Abnormalities in Spontaneous Coronary Artery Dissection (2021) (9)
Is Southern blotting necessary to measure telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements. (2015) (9)
Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic. (2015) (9)
Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
The value of spot urinary creatinine as a marker of muscle wasting in patients with new‐onset or worsening heart failure (2021) (8)
Cumulative effects of common genetic variants on risk of sudden cardiac death (2015) (8)
Correction: The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits (2013) (8)
Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits : (Nature Genetics, (2018), 50, 10, (1412-1425), 10.1038/s41588-018-0205-x) (2018) (8)
Investigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length (2022) (8)
Genetic risk and atrial fibrillation in patients with heart failure (2020) (8)
Corrigendum to: ms1, a novel stress‐responsive, muscle‐specific gene that is up‐regulated in the early stages of pressure overload‐induced left ventricular hypertrophy (FEBS 26169) (2002) (8)
Association of Factor V Leiden With Subsequent Atherothrombotic Events (2020) (8)
Signatures of miR-181 a on the Renal Transcriptome and Blood Pressure (2016) (8)
Association between up‐titration of medical therapy and total hospitalizations and mortality in patients with recent worsening heart failure across the ejection fraction spectrum (2021) (7)
Remote ischaemic conditioning and remodelling following myocardial infarction: current evidence and future perspectives (2016) (7)
Vascular renin and hypertension. Uptake versus synthesis. (1990) (7)
Alcohol consumption and telomere length: Mendelian randomization clarifies alcohol’s effects (2022) (7)
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium (2019) (7)
Disparity in implantable cardioverter defibrillator therapy among minority South Asians in the United Kingdom (2020) (7)
The FcγRIIa His131Arg polymorphism and its association with myocardial infarction (2004) (7)
Expression of components of the RAS during prolonged blockade at different levels in primates. (1994) (7)
Correction: Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study (2008) (7)
Effects of exercise and nitrates on blood flow in internal mammary artery to coronary artery grafts: a non-invasive study. (1995) (7)
Normotensive blood pressure in mice with a disrupted renin Ren-1d gene (1997) (7)
Two Further Blood Pressure Loci Identified in Ion Channel Genes With a Genecentric Approach (2014) (7)
Cis-epistasis at the LPA locus and risk of cardiovascular diseases (2021) (7)
Interpreting regional myocardial magnetic resonance imaging data: a new method for collation with angiographic findings in patients with coronary artery disease. (2002) (7)
Effects of the coronary artery disease associated LPA and 9p21 loci on risk of aortic valve stenosis. (2019) (7)
Discovering patterns of pleiotropy in genome-wide association studies (2018) (7)
Molecular Biology of the Renin‐Angiotensin System: Implications for Hypertension and Beyond (1991) (7)
Contribution of NOTCH1 genetic variants to bicuspid aortic valve and other congenital lesions (2022) (6)
Systemic cholesterol crystal embolisation with pulmonary involvement: a fatal combination after coronary angiography (2002) (6)
Evidence for reduced susceptibility to cardiac bradycardias in South Asians compared with Caucasians (2018) (6)
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (6)
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
Influence of non-invasive measurements of arterial blood pressure in frequency and time-domain estimates of cardiac baroreflex sensitivity (2008) (6)
Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
Genetic Associations with Plasma ACE2 Concentration: Potential Relevance to COVID-19 Risk. (2020) (6)
Differential miRNAs in acute spontaneous coronary artery dissection: Pathophysiological insights from a potential biomarker (2021) (6)
Are baroreflex events detected by invasive and non‐invasive techniques coincident? (2008) (6)
Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT‐CHF (2020) (6)
The narrow-sense and common single nucleotide polymorphism heritability of early repolarization. (2019) (6)
SA gene and hypertension. (1995) (6)
Methylenetetrahydrofolate reductase mutation and coronary artery disease. (1998) (5)
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk (2017) (5)
Sunday, 26 August 2012 (2012) (5)
The renin gene in patients with malignant hypertension and raised plasma renin activity. (1989) (5)
Pharmacogenomics of hypertension: a realizable goal? (2000) (5)
Telomere attrition rate in a longitudinal population study (2008) (5)
Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure (2019) (5)
Chromosome 1p shows significant linkage to steroid metabolism in hypertension in the British Genetics of Hypertension Study (2006) (5)
HeterozygousABCG5Gene Deficiency and Risk of Coronary Artery Disease (2020) (5)
Using matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) profiling in order to predict clinical outcomes of patients with heart failure (2018) (5)
Association studies in current cardiovascular genetics – functional variants, tags or both? (2007) (5)
Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders (2018) (5)
Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure (2022) (5)
Heteroplasmic mitochondrial DNA variants in cardiovascular diseases (2022) (5)
Evidence for Accelerated Biological Aging in Young Adults with Prader–Willi Syndrome (2019) (4)
208 The PKC Epsilon/AMPK ALPHA/ENOS Pathway is Implicated as a Mechanism by which Remote Ischaemic Conditioning Attenuates Endothelin-1 Mediated Cardiomyocyte Hypertrophy (2014) (4)
Improving the delivery of coronary care for ethnic minorities (2003) (4)
Albuminuria as a marker of systemic congestion in patients with heart failure (2022) (4)
Clinical implications of low estimated protein intake in patients with heart failure (2022) (4)
69 Genome wide methylation analysis in coronary artery disease (2011) (4)
Approaches to the analysis of complex quantitative phenotypes and marker map construction based on the analysis of rat models of hypertension. (2002) (4)
Elucidation of the genetic causes of bicuspid aortic valve disease (2022) (4)
Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing (2022) (4)
The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis (2022) (4)
Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis. (2020) (4)
Inheritance of coronary artery disease in men – Authors’ reply (2012) (4)
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells (2020) (4)
Surrogate markers of gut dysfunction are related to heart failure severity and outcome - from the BIOSTAT-CHF consortium. (2022) (4)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
Insulin‐like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence (2022) (4)
Association of shorter leucocyte telomere length with risk of frailty (2022) (4)
Genetic epidemiology of hypertension (2007) (4)
Rapid Review of ECG Interpretation (2005) (4)
Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure (2020) (4)
THE KIF6 719ARG ALLELE IS ASSOCIATED WITH INCREASED RISK OF CORONARY HEART DISEASE AMONG MALES IN THE WELCOME TRUST CASE CONTROL CONSORTIUM STUDY OF CORONARY HEART DISEASE (2009) (4)
Distinct pathophysiological pathways in women and men with heart failure (2022) (4)
Chromosome 2p Shows Genome Wide Significant Linkage to Anti-Hypertensive Medication Response in the British Genetics of Hypertension (BRIGHT) Study.: LB57 (2005) (3)
Supplementary Material 6 (2014) (3)
A preclinical ultrasound method for the assessment of vascular disease progression in murine models (2018) (3)
Genetics of educational attainment and coronary risk in Mendelian randomization studies. (2020) (3)
Effects of Coronary Artery Disease–Associated Variants on Vascular Smooth Muscle Cells (2022) (3)
Short leucocyte telomere length is associated with abdominal aortic aneurysm (2009) (3)
Abstract 19823: Whole-Exome Sequencing in an Extended Family with Myocardial Infarction Identified a Potential Functional Mutation in PDE5A (2012) (3)
Supplementary Material 3 (2015) (3)
Longitudinal telomere length and body composition in healthy term-born infants during the first two years of life (2021) (3)
The genomics of heart failure: design and rationale of the HERMES consortium (2021) (3)
The MRC British Genetics of Hypertension Study - Genome-wide screen results (2002) (3)
Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility (2020) (3)
Variation in Human Herpesvirus 6B telomeric integration, excision and transmission between tissues and individuals (2021) (3)
Urinary albumin excretion in hypertensive siblings in the British Genetics of Hypertension study (2007) (3)
Telomere length variation reduces with age: evidence of survivor effect (2014) (3)
Causal Associations of Self-Reported Walking Pace with Telomere Length in 405,981 middle-aged adults: a UK Biobank study (2021) (3)
Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease (2021) (3)
A miR-327–FGF10–FGFR2-mediated autocrine signaling mechanism controls white fat browning (2017) (3)
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (3)
Pathophysiological pathways in patients with heart failure and atrial fibrillation (2021) (3)
Multimarker profiling identifies protective and harmful immune processes in heart failure: findings from BIOSTAT-CHF (2021) (3)
Pathophysiologic Processes and Novel Biomarkers Associated With Congestion in Heart Failure. (2022) (3)
Use of polygenic risk scores and other molecular markers to enhance cardiovascular risk prediction: prospective cohort study and modelling analysis (2019) (3)
The renin-angiotensin system in cardiovascular physiology and disease: new insights from molecular studies. (1993) (3)
Ultrasound shear wave elastography imaging of common carotid arteries in patients with Spontaneous Coronary Artery Dissection (SCAD) (2022) (3)
Older biological age is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank (2021) (3)
Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure (2022) (3)
Supplementary Material 5 (2014) (3)
Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology (2019) (3)
Ventricular aneurysmectomy: indications, operative findings and outcome at a single centre. (1994) (3)
Exome Sequencing Analysis Identifies Rare Variants in ATM and RPL8 That Are Associated With Shorter Telomere Length (2020) (3)
Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing (2012) (3)
Supplementary Material 7 (2014) (3)
Into the great wide open: 10 years of genome-wide association studies. (2018) (2)
Novel LOX Variants in Five Families with Aortic/Arterial Aneurysm and Dissection with Variable Connective Tissue Findings (2021) (2)
214 Generation of Isogenic Cell Lines to Study a Single Disease Associated Variant at the 1P13 Cad Risk Locus (2014) (2)
Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney (2017) (2)
Whole genome sequencing finds rare high-risk genotypes for hip osteoarthritis in the COMP and CHADL genes (2017) (2)
Adding Genetic Markers to Classic Risk Factors - An Enhanced Coronary Risk Score Based on the Morgam Prospective Cohorts (2011) (2)
A new tool for checks of data precision within the MRC British genetics of hypertension study (2000) (2)
Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure (2022) (2)
Professor John Douglas Swales, MD, FRCP: 1935–2000 (2001) (2)
Association between Variants of the Human GSTM Gene Family and Hypertension: 8 (2006) (2)
Whole-genome sequencing of a sporadic primary immunodeficiency cohort (2020) (2)
A molecular dynamics study of C1r and C1s dimers: Implications for the structure of the C1 complex (2012) (2)
Elucidating the genetic basis of spontaneous hypertension: a perspective. (1993) (2)
Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals (2021) (2)
Analysis of gene-gene interactions among common variants in coronary artery disease (2014) (2)
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (2)
Genetic loci influencing C-reactive protein levels and coronary heart disease risk: results of genetic association and Mendelian randomisation study with meta-analysis in 80 614 people (2009) (2)
Premature coronary artery disease shows no evidence of linkage to loci encoding for tissue inhibitors of matrix metalloproteinases (2003) (2)
New training guidelines: what are the implications for cardiological research? (1996) (2)
Interethnic analyses of blood pressure loci in populations of East Asian and European descent (2018) (2)
Application of two novel electrical restitution‐based ECG markers of ventricular arrhythmia to patients with nonischemic cardiomyopathy (2020) (2)
Abstract 1879: Genetic Variation at Chromosome 1p13.3 Affects Sortilin mRNA Expression, Cellular LDL Uptake and Serum LDL Levels Which Translates to the Risk of Coronary Artery Disease (2009) (2)
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential (2007) (2)
Visualisation of exhaled breath metabolites reveals distinct diagnostic signatures for acute cardiorespiratory breathlessness (2022) (2)
Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease (2019) (2)
Expression of myocyte stress 1 (ms1), a novel gene involved in cardiac development and hypertrophy is regulated by evolutionarily conserved GATA motifs (2007) (2)
Cis-epistasis at the LPA locus and risk of coronary artery disease (2019) (2)
Long-term trends in the epidemiology of cardiovascular diseases in the UK: Insights from the British Heart Foundation Statistical Compendium. (2022) (2)
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (1)
Phenotype and Genotype Comparison of Hereditary Hypertriglyceridemic (hHTG) and Brown‐Norway (BN) Rats Identification of Quantitative Trait Loci (QTLs) for the Insulin Resistance Syndrome a (1997) (1)
The renin gene and its expression in hypertension. (1994) (1)
Modifiable traits, healthy behaviours, and leucocyte telomere length (2021) (1)
22Combining a novel electrical restitution based biomarker with heart rate variability analysis improves prediction of sudden cardiac death risk (2014) (1)
ED-36INHERITED VARIANTS NEAR TERC AND TERT ARE ASSOCIATED WITH LONGER TELOMERES AND INCREASED GLIOMA RISK: GENOME-WIDE ASSOCIATION RESULTS FROM THE UCSF ADULT GLIOMA STUDY AND THE ENGAGE CONSORTIUM TELOMERE GROUP (2014) (1)
Tuesday, 28 August 2012 (2012) (1)
The association of the chromosome 9p21 locus on risk of coronary artery disease is not mediated by an effect on telomere length (2009) (1)
Application of two novel electrical restitution based ECG markers of ventricular arrhythmia to patients with non-ischemic cardiomyopathy (2020) (1)
Effects of late, repetitive remote ischaemic conditioning on myocardial strain in patients with acute myocardial infarction (2022) (1)
RARE LOSS-OF-FUNCTION MUTATIONS OF PTGIR IDENTIFIED IN FIBROMUSCULAR DYSPLASIA AND SPONTANEOUS CORONARY ARTERY DISSECTION (2019) (1)
Pleiotropic molecular targets of coxibs reveals novel genomic loci conferring coronary artery disease risk (2016) (1)
Letters to the Editor Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and LjubomirButurovic (2015) (1)
Transcript expression-aware annotation improves rare variant interpretation (2020) (1)
High glucose and low lactate: a metabolic signature of hypertension in human serum? (2008) (1)
Identification of heart rate-associated loci and genes (2013) (1)
108 Remote ischaemic conditioning is impaired in diabetes (2012) (1)
Coronary heart disease Plasma matrix metalloproteinase-9 and left ventricular remodelling after acute myocardial infarction in man : a prospective cohort study (2007) (1)
Discovery and Refinement Supplementary (2015) (1)
Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity (2018) (1)
1 DNA fingerprinting of spontaneously hypertensive and Wistar‐Kyoto rats: a method of analysing the genetic basis of hypertension in the spontaneously hypertensive rat (1988) (1)
Over-expression of myocyte stress 1 protein in vitro switches on the fetal gene programme and anti-apoptotic pathways (2005) (1)
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (1)
Telomere length is independently associated with all-cause mortality in chronic heart failure (2021) (1)
Prevention of coronary heart disease with pravastatin. (1996) (1)
A major polymorphism in the rat SA gene caused by the insertion of a LINE element (1996) (1)
Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (2021) (1)
Supplementary Material 9 (2013) (1)
The Relationship Between Plasma Angiopoietinlike Protein 4 Levels , Angiopoietinlike Protein 4 Genotype , and Coronary Heart Disease Risk (2010) (1)
Telomere length is shorter in healthy offspring of individuals with coronary artery disease (2008) (1)
2. Renal and extra-renal renin gene expression - effects of salt intake, hypertension and genetic background (1988) (1)
Title : Polymorphisms in the WNK 1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion (2009) (1)
Physical activity and sedentary behavior; mechanistic insights and role in disease prevention (2021) (1)
Causal Effects of Adiposity on Cardiovascular Risk Factors (2015) (1)
Supplementary Material 4 (2015) (1)
Telomere length is an independent risk factor for anaemia in patients with chronic heart failure (2009) (1)
Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
69 A FUNCTIONAL GENETIC VARIANT OF FGF1 IS ASSOCIATED WITH BLOOD PRESSURE IN THE GENERAL POPULATION (2012) (1)
Faculty Opinions recommendation of Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials. (2008) (1)
Abstract 15829: Periadvential Inflammation in Spontaneous Coronary Artery Dissection: Causal Role or Response to Injury? (2018) (1)
The role of adiposity in cardiometabolic traits (2013) (1)
Editorial comment: Genetics and molecular biology (1992) (1)
No Association of the Wnk1 Gene With Essential Hypertension in the Mrc Bright Study (2004) (1)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (1)
ANGPTL3 De ﬁ ciency and Protection Against Coronary Artery Disease (1)
The FES gene, located at the chromosome 15Q21.6 coronary-artery-disease locus, modulates atherosclerotic plaque vulnerability (2020) (1)
disease Biological ageing and cardiovascular (2008) (1)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
Synthase Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Polymorphism Array and Case-Control Design Identifies a Novel Essential Genomewide Association Study Using a High-Density Single Nucleotide (2011) (1)
No support for linkage of chromosome 17(q21-24) to Essential Hypertension in the MRC British Genetics of Hypertension (MRC BRIGHT) Study. (2001) (1)
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus (2020) (1)
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits (2019) (1)
Analysis of the angiotensinogen gene in the MRC British genetics of Hypertension study. (2015) (1)
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort (2020) (1)
Abstract 19822: Ldlr Splice-Site Mutation (ivs9-1g>A) Identified by Whole-Exome Sequencing in an Extended Family with Myocardial Infarction (2012) (1)
KCND3 is a novel susceptibility locus for early repolarization (2019) (1)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
Genome-Wide Association Study of Over One Million Participants Identifies 49 Novel Loci Associated With Coronary Artery Disease (2019) (1)
Abstract 17557: Genetic Variants Primarily Associated eith Type 2 Diabetes Also Affect Coronary Artery Disease Risk (2012) (1)
Increased Renin Gene Expression in the Kidney of 5 Weeks Old Spontaneously Hypertensive Rat (1988) (1)
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease (2022) (1)
Supplementary Material 15 (2013) (1)
Abstract 17892: Network-Driven Integrative Genomics Analysis of the Cardiogram Gwas Reveals Key Drivers and Subnetworks of Coronary Artery Disease (2011) (1)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (1)
The renin-angiotensin system: Biochemistry, physiology, pathophysiology and therapeutics: Editors: J.I.S. Robertson and M.G. Nicholls Mosby Year Book, Europe, Aylesford, Kent, UK, 1993; 1500 pp.; stg£150.00; ISBN 1-56375-550-5 (1993) (1)
Genes, circadian clock and nocturnal blood pressure. (2009) (1)
The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1 (2022) (1)
Exome-chip meta-analysis identifies novel loci, including ADAMTS6 associated with cardiac conduction (2018) (1)
Genetics for Cardiologists: The Molecular Genetic Basis of Cardiovascular Disorders (2002) (1)
Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
Relationship between an electrocardiogram based measure of action potential duration (APD) restitution and autonomic function in patients with ischaemic cardiomyopathy (2014) (1)
Association of MARC1 A165T with metabolic traits. (2020) (0)
Mendelian randomization analysis of red cell distribution width in pulmonary arterial hypertension (2019) (0)
University of Dundee The PCSK9-LDL Receptor Axis and Outcomes in Heart Failure Bayes-Genis, (2017) (0)
QTLs for plasma triglyceride levels in the F2hybrid (hHTgxBN) population derived from the hereditary hypertriglyceridemic rat (2000) (0)
Evaluating drug targets through human loss-of-function genetic variation (2020) (0)
Whole-genome sequencing of patients with rare diseases in a national health system (2020) (0)
WNK1 - functional analyses of variants associated with blood pressure and essential hypertension (2008) (0)
Systematic analysis of 123 candidate genes reveals two novel genes for hypertension (2008) (0)
Abstract 18455: Genome Editing Identifies a Functional Role for the Lead Variant at the ZC3HC1 Coronary Artery Disease Risk Locus in Cell Cycle Regulation (2014) (0)
UB Researc (2009) (0)
Lack of association between air pollutants and telomere length: findings from the UK Biobank study (2022) (0)
Variants of the human mu type glutathione-s-transferase (GSTM) gene family are associated with hypertension (2006) (0)
Assessment of Proximal Tubular Function by Tubular Maximum Phosphate Reabsorption Capacity in Heart Failure (2022) (0)
Genetic variants associated with celiac disease and the risk for coronary artery disease (2015) (0)
Genetic risk prediction of atrial fibrillation in a contemporary heart failure cohort (2019) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
6 The effects of ACE inhibition on extrarenal renin mRNA levels (1991) (0)
The mutational constraint spectrum quantified from variation in 141,456 humans (2020) (0)
Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
Validation of Association of Hypertension at the CYP11B1/B2 Locus in Caucasians. (2010) (0)
Abstract MP57: Pathway and Network Analysis of GWAS reveals Novel Candidate Causal Links between Key Biological Processes and Coronary Artery Disease (2014) (0)
Telomere length predicts left ventricular mass in a general population (2009) (0)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
3WS16-2 Molecular genetics of experimental hypertension: An update (2003) (0)
Low birth weight in MZ twins discordant for birth weight is associated with shorter telomere length and lower IQ, but not anxiety/depression in later (2017) (0)
79 Extrarenal expression of the renin gene: relevance to cardiovascular homeostasis and disease (1988) (0)
120 PHYLOGENETIC ANALYSIS OF THE Y CHROMOSOME IN ABDOMINAL AORTIC ANEURYSMS: A META-ANALYSIS OF THREE BRITISH COHORTS (2012) (0)
Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction. (2023) (0)
Myocyte stress 1 plays an important role in hypertrophy and cardioprotection via a myocardin-related transcription factor/serum response factor signalling pathway (2009) (0)
Common carotid artery stiffness in patients with Spontaneous Coronary Artery Dissection (SCAD) is comparable to non-dissection controls (2020) (0)
Abstract 366: Evidence For Genetic Variations Associated With Increased Risk Of Left Main Disease At Chromosome 9p21 (2007) (0)
Lecture notes on molecular medicine: Editors: J. Bradley, D. Johnson, D. Rubenstein Blackwell Science, Abingdon, UK, 1995; 151 pp.; £12,95; ISBN: 0-632-03851-9 (1996) (0)
MO374: Urinary Cell Transcriptomics Provides a Non-Invasive Readout of Kidney Genes Essential to Renal Health and Disease (2022) (0)
Bleeding tonsils. (1991) (0)
128 Clinical impact of changes in mitral regurgitation severity after optimization of medical therapy in heart failure: insights from BIOSTAT-CHF (2021) (0)
Potassium and the use of RAAS inhibitors in Heart Failure 5 with reduced ejection fraction : data from BIOSTAT-CHF 6 (2017) (0)
Discovery of novel genes for serum urate and low-density lipoprotein cholesterol - Two biomarkers of cardiovascular disease (2007) (0)
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
Abstract 15267: A Novel Surface ECG Based Marker of Ventricular Arrhythmia in Patients with Ischaemic Cardiomyopathy (2012) (0)
Increased levels of tissue factor-bearing microparticles in patients with premature myocardial infarction (2014) (0)
Edinburgh Research Explorer Secretory Phospholipase A2-IIA and Cardiovascular Disease (2018) (0)
Transient therapeutic inhibition of MASP-2 dependent lectin pathway functional activity provides a significant degree of protection from ischaemia/reperfusion injury in models of myocardial infarction and stroke (2013) (0)
The Plasminogen Activators in Intimal Hyperplasia (1997) (0)
Theme I: genetic animal models in hypertension: where do things stand and where are they going? (1999) (0)
PS-BPB06-5: URINARY CELL TRANSCRIPTOMICS: A NON-INVASIVE EXPRESSION READOUT OF KIDNEY GENES OF RELEVANCE TO HYPERTENSION (2023) (0)
Dietary patterns and practices and leucocyte telomere length: Findings from the UK Biobank. (2023) (0)
423 ANDROGENS AND AGGRESSIVENESS DO NOT MEDIATE THE EFFECT OF THE Y CHROMOSOME ON CARDIOVASCULAR RISK (2012) (0)
Translational medicine Genetics of myocardial infarction : a progress report (2010) (0)
A15452 Kidney DNA methylation as a driver of genetic changes in hypertension (2018) (0)
Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease (2018) (0)
Genetic risk stratification in patients undergoing coronary artery bypass graft (CABG) surgery: relative allele frequencies of leading SNPs associated with CAD/MI (2010) (0)
Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2020) (0)
075 Effect of aortic valve replacement on LV remodelling and matrix metalloproteinases and their tissue inhibitors in isolated severe aortic stenosis (2012) (0)
Title : Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (0)
A structural variation reference for medical and population genetics (2020) (0)
1 Subsequent Event Risk in Individuals with Established Coronary Heart Disease : Design and Rationale of the GENIUS-CHD Consortium Running title : (2019) (0)
Edinburgh Research Explorer Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease (2013) (0)
076 Failure of aortic valve replacement to improve objective functional capacity in patients with isolated severe aortic stenosis (2012) (0)
Distribution of characteristics of the study population (n = 3,000) by PTSD status. (2013) (0)
response to stress Mapping of genetic determinants of the sympathoneural (2013) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Gender differences in left ventricular geometry and determinants of myocardial perfusion reserve in patients with severe aortic stenosis (2011) (0)
Heart failure with normal LVEF in BIOSTAT-CHF. (2022) (0)
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure. (2023) (0)
A Y Chromosome Haplogroup Increases Risk of Coronary Artery Disease (2011) (0)
Abstract 16709: Heritability of Early Repolarization - a Population-Based Study (2010) (0)
Supplementary Material (nature09270-s1) (2012) (0)
Association of Blood Pressure With Genetic Variation in WNK Kinases in a White European Population (2005) (0)
Author Correction: Investigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length (2022) (0)
Association of leucocyte telomere length with frailty: a large-scale cross-sectional analysis in UK Biobank (2021) (0)
Abstract 17297: 9p21 CAD Risk Allele is Protective Against Calcific Aortic Stenosis (2014) (0)
Genomewide linkage analysis for loci affecting electrocardiographic LV mass (2006) (0)
IN SILICO DRUG REPOSITIONING OF TOPIRAMATE AS AN ANTIHYPERTENSIVE BY CONVERGING KIDNEY TRANSCRIPTOMIC, EPIGENOMIC AND GENOMIC DATA (2021) (0)
A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors (2017) (0)
Olovnikov's clock and coronary artery disease (2007) (0)
Evidence Tor Inherited Risk of Thrombosis in Families with Premature Myocardial Infarction (2003) (0)
Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome (2022) (0)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (0)
The MRC BRIGHT study: Demographic and biochemical characteristics of the sibling-pair resource (2004) (0)
Abstract 16094: RAB3 GTPase Activating Protein Subunit 1 is a Novel Candidate Gene for Sudden Cardiac Death (2012) (0)
Distribution of ancestry in each cohort. (2020) (0)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years (2017) (0)
GENES ASSOCIATED WITH BLOOD PRESSURE TRAITS SHOW CELL TYPE-SPECIFIC EXPRESSION AND CONTROL MULTIPLE CAUSAL LINKS TO BLOOD PRESSURE REGULATION IN THE HUMAN KIDNEY (2021) (0)
Comparison of the Renin Gene and Its Expression in the Kidneys of Spontaneously Hypertensive and Wistar-Kyoto Rats (1987) (0)
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals (2018) (0)
83 The coronary artery disease associated gene JCAD regulates hippo signalling in endothelial cells (2018) (0)
Abstract 18432: Global Transcriptional Profiling of Monocytes and Macrophages and Association with Coronary Artery Disease Risk Factors in a Large Multi-Center Collaborative Study: The Cardiogenics Transcriptomic Study (2011) (0)
14th European meeting on Complement in Human Disease (2013) (0)
Telomere Length in Young Adults Born Preterm and the Risk for Cardiovascular Disease; Support for Accelerated Biological Ageing in Subjects Born Preterm (2015) (0)
Haplotype effects derived from the rs317657 and rs11177644 at the 12q15 locus in the Gutenberg Health Study (N = 1,467). (2012) (0)
Erratum to: Vascular histopathology and connective tissue ultrastructure in spontaneous coronary artery dissection: pathophysiological and clinical implications (2022) (0)
Coronary artery disease variant and cell cycle (2016) (0)
Acute, reversible type II (Wenkebach) heart block due to combined chloroquine and diltiazem treatment (2003) (0)
A conserved E-box module drives rhythmic mouse Pai-1 transcription in vitro and provides a cognate binding site clock and hypoxic factors (2007) (0)
Does CRP Play a Causal Role in the Development of Coronary Heart Disease: Results of a Mendelian Randomisation Experiment Involving 128,935 People (2009) (0)
M66 Newborns´ Telomere Length Is Related To Their Mothers´ Stress During Pregnancy And To Their Fathers´ Life-Time Psychiatric Disorder (2017) (0)
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits (2018) (0)
Discovery and validation of 107 blood pressure loci from UK Biobank offers novel biological insights into cardiovascular risk (2016) (0)
3894Predictors of non-adherence to antihypertensive treatment: insights from liquid chromatography tandem mass spectrometry based analysis (2017) (0)
Gene-gene interactions in coronary artery disease (2012) (0)
126 CHROMOSOME 9P21 LOCUS AND ANGIOGRAPHIC CORONARY ARTERY DISEASE BURDEN: A COLLABORATIVE META-ANALYSIS (2013) (0)
Genes With Evidence for Association With Bicuspid Aortic Valve Gene (0)
Disease Presenting as Autosomal Recessive Hypercholesterolemia Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage (2013) (0)
5Improving sudden cardiac death risk stratification in patients with ischaemic cardiomyopathy: a combined electrocardiogram and plasma biomarker approach (2014) (0)
P-151: Association study of 7 candidate genes with essential hypertension in subjects of African ancestry (2001) (0)
Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets (2018) (0)
Novel application of electrical restitution predicts sudden cardiac death risk independently of existing risk markers (2013) (0)
Characterising phenotype in genetic studies of blood pressure (2004) (0)
Circulating microRNAs and hypertension (2017) (0)
Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes (2020) (0)
The John Swales Lecture: a new initiative to honour the founding editor of the Journal of Hypertension. (2012) (0)
Comparison of Mrna Transcripts of the Shr and Wky SA Gene, a Putative Gene Regulating Blood Pressure (1996) (0)
Reply to the Letter by Hayashi et al (2011) (0)
P6551Coronary artery disease risk is influenced by epigenetically active variants on the Y chromosome (2018) (0)
Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression (2012) (0)
Abstract 14363: Genetics of Coronary Atherosclerotic Plaque Rupture and Myocardial Infarction (2010) (0)
A The Coronary Artery Disease Associated Gene HHIPL1 Promotes Atherosclerosis (2016) (0)
Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. (2017) (0)
Genetics of hypertension and blood pressure regulation : progress in the last 10 years (2007) (0)
Genetic Identification of Markers on the Surface of Damaged Endothelial Cells (1996) (0)
12 Is echocardiography alone sufficient for reliable cascade screening of first degree relatives of patients with bicuspid aortic valves? (2017) (0)
Analysis of the Postulated Interaction between the at II Sub-Type 1 Receptor Gene A1166-C Polymorphism and the ACE Gene I/D Polymorphism on Risk of MI (2000) (0)
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Myocardial Infarction Genetics Consortium * (2009) (0)
149 Reduced renal afferent arteriole diameter at 7 weeks is a predictor of increased blood pressure at 23 weeks in F2 generation spontaneously hypertensive and Wistar-Kyoto rats (1993) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals (2021) (0)
Using matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) profiling in order to predict clinical outcomes of patients with heart failure (2018) (0)
University of Groningen Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation (2018) (0)
Familial Atherosclerotic Disease and Hypertension Localised To Chromosome 7p in the British Genetics of Hypertension Study: LB19 (2006) (0)
Y Chromosome Haplogroup as a Predictor of Coronary Artery Disease in Men (2010) (0)
TELOMERE LENGTH VARIANTS ARE ASSOCIATED WITH HIGH-GRADE GLIOMA RISK: IDENTIFICATION OF A NOVEL GLIOMA RISK LOCUS BY GENOME-WIDE ASSOCIATION STUDY (2014) (0)
Angiotensinogen Gene Variants do not Affect Ambulatory Blood Pressure in the General Population: P97 (2006) (0)
Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank (2022) (0)
MPS 01-02 GENOME WIDE HOMOZYGOSITY ANALYSIS - ASSOCIATION WITH CORONARY ARTERY DISEASE AND GENE EXPRESSION IN MONOCYTES AND MACROPHAGES (2016) (0)
Abstract 15963: Toward Development of a Genetic Risk Score for Sudden Cardiac Death (2014) (0)
Identification and Characterization of novel long non-coding RNAs in vascular smooth cells (2023) (0)
Association of the CYP11B1 and CYP11B2 gene polymorphisms with hypertension in the British Genetics of Hypertension case-control study (2007) (0)
Replicated association of regions at CYP11B1/B2 locus with hypertension in Caucasians (2010) (0)
A System-Wide Investigation and Stratification of the Hemostatic Proteome in Premature Myocardial Infarction (2022) (0)
Loci on Chromosomes 5p and 20q are Linked to Multiple Hypertension Phenotypes in the BRItish Genetics of HyperTension (BRIGHT) Study: LB13 (2005) (0)
058 Fibroblast growth factor binding protein 1 gene (FGFBP1) and hypertension — from pathway analysis to renal glomerulus (2010) (0)
Author Correction: Evaluating drug targets through human loss-of-function genetic variation (2021) (0)
SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells (2018) (0)
The role of extrarenal renin in Goldblatt hypertension. (1991) (0)
The Effect of Surgical Preparation of Saphenous Vein Coronary Artery Conduits on Vessel Wall Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 (1996) (0)
210 Investigation of the Functional Role of the Lead Variant at the ZC3HC1 Coronary Artery Disease Locus in Cell Cycle Regulation using a Genome Editing Approach (2015) (0)
The coronary artery disease associated variant at 10q23.31 is associated with increased lysosomal acid lipase A activity (2014) (0)
Molecular genetics of hypertension (1995) (0)
Kidney DNA methylation as a driver of genetic change in the kidney (2018) (0)
Relation of microvascular dysfunction to exercise capacity and symptoms in patients with severe aortic stenosis (2011) (0)
Myocyte Stress 1 (ms1): a novel nexus that integrates the SRF and GATA4 cardiac gene regulatory networks (2007) (0)
Abstract 1885: Telomere Length Predicts Anaemia in Patients With Chronic Heart Failure and is Inversely Associated With Haemoglobin Levels (2009) (0)
Large-Scale Analysis of the Association between Air Pollutants and Leucocyte Telomere Length in the UK Biobank (2023) (0)
University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
KIDNEY DNA METHYLATION AS A DRIVER OF HERITABLE PREDISPOSITION TO BLOOD PRESSURE AND HYPERTENSION (2021) (0)
P336Generation of vascular cell types from human pluripotent stem cells: an in vitro model for the study of coronary artery disease genetic loci (2018) (0)
Rat chromosome 1 blood pressure quantitative trait locus mediates its effect via the kidney. (2001) (0)
183 The Sa gene locus cosegregates with increased blood pressure in the spontaneously hypertensive rat (1993) (0)
Uncovering genetic mechanisms of kidney aging epigenomics (2019) (0)
Author Correction: Transcript expression-aware annotation improves rare variant interpretation (2021) (0)
A colour Atlas of hypertension, 2nd edition: L.M. Shapiro and M. Buchalter Wolfe, London, 1992; 159 pp.; US$35.00; ISBN 0-7234-1637-0 (1993) (0)
Abstract 18993: Genetic Variants Primarily Associated With Inflammatory Bowel Disease Do Not Associate With Coronary Artery Disease (2014) (0)
Author response: Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals (2021) (0)
Thrombotic potential may be increased in healthy individuals with a two-generation family history of premature myocardial infarction (2003) (0)
1044 Hypertension November 2017 Initially Nonadherent Hypertensive Patients Show Steeper Reduction in BP on Follow-Up Appointments Than Those Who Are Initially (2017) (0)
Abstract 16492: A Study of 63,253 Cases and 126,820 Controls Identifies Multiple Novel Loci for Coronary Artery Disease and Detects Independent Signals in Many of the Established Ones (2011) (0)
Changes in Vessel Wall Urokinase Type Plasminogen Activator and Its Receptor following Experimental Angioplasty (1996) (0)
Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus (2022) (0)
224 Blood pressure in the spontaneously hypertensive rat is not linked to the sex chromosomes (1993) (0)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2020) (0)
University of Dundee Using matrix assisted laser desorption ionisation mass spectrometry ( MALDI-MS ) profiling in order to predict clinical outcomes of patients with heart failure (2018) (0)
TRANSLATING SIGNALS FROM GENOME-WIDE ASSOCIATION STUDIES INTO BIOLOGICAL MECHANISMS OF HYPERTENSION THROUGH KIDNEY -OMICS (2019) (0)
Molecular insights into genome-wide association studies of chronic kidney disease-de ﬁ ning traits (2018) (0)
Remote ischaemic conditioning attenuates endothelin-1 induced hypertrophic response in rat cardiomyoblasts (2012) (0)
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
PSeudoautosomal region 1 and predisposition to coronary artery disease. (2017) (0)
Body surface restitution gradient predicts sudden cardiac death risk in a clinical study (2013) (0)
Effect of Small Size at Birth, Adult Body Size and Growth Hormone Treatment on Telomere Length (2016) (0)
Abstract 3142: Do Known Genetic Factors Contribute to the Increased Risk of Cardiovascular Disease Amongst Indian Asians? (2008) (0)
Title Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk Permalink (2016) (0)
Professor Anthony H. Gershlick. (2021) (0)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure (2020) (0)
Platelet GPIa (G873/873A) and GPIIbIIIa (leu33/33pro, PIA1/PIA2) glycoprotein receptor polymorphisms: an analysis of functional effects and association with risk of premature myocardial infarction (2002) (0)
Genetic association of lipids and lipid drug targets in abdominal aortic 1 aneurysm 2 3 4 (2018) (0)
ORM1: a novel regulator of thrombin generation and potential cardiovascular risk factor (2014) (0)
Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans (2021) (0)
Investigating the potential effects of platelet-derived exosomal microRNA on monocyte gene expression (2014) (0)
S-38-2: PREVENTION OF EXPERIMENTAL GENETIC HYPERTENSION - GENOMIC CLUES FROM THE KIDNEY (2023) (0)
The effect of LRRK2 loss-of-function variants in humans (2020) (0)
University of Dundee Non-cardiac Comorbidities in Heart Failure with Reduced , Mid-range and Preserved Ejection (2018) (0)
Biomarker changes as surrogate endpoints in early‐phase trials in heart failure with reduced ejection fraction (2022) (0)
A large scale analysis of determinants and heritability of HDL efflux capacity (2015) (0)
Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure (2023) (0)
Correction to: The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure (2020) (0)
Rare sequence variants that disrupt ASGR 1 function lower non-HDL cholesterol and protect against coronary artery disease (2016) (0)
COMMON OR RARE GENETIC VARIATION IN THE CHEMOKINE RECEPTORS CCR2, CCR5, AND CX3CR1 DOES NOT RELATE TO CORONARY HEART DISEASE OR MYOCARDIAL INFARCTION IN HUMANS (2016) (0)
Telomere length and brain imaging phenotypes in UK Biobank (2023) (0)
Evidence for a shared genetic determination of Ischemic Stroke And Coronary Artery Disease - a genome-wide analysis (2013) (0)
Novel body surface electrical restitution based marker is predictive of sudden cardiac death risk independent of existing risk markers (2013) (0)
Author Correction: A structural variation reference for medical and population genetics (2021) (0)
Edinburgh Research Explorer Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease (2018) (0)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
Detecting a high likelihood of hypertension – using hypertension marker proteins (2001) (0)
Genetic and modifiable risk factors combine multiplicatively in common disease (2022) (0)
protein regulating platelet function Transcription profiling in human platelets reveals LRRFIP1 as a novel (2010) (0)
23 The Role of AMPK and PKCε in the Attenuation of ET-1 Induced Cardiomyocyte Hypertrophy by RIC Human Serum (2014) (0)
Abstract 5904: Telomere Length and Outcome in Heart Failure (2008) (0)
Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure. (2023) (0)
Spontaneous coronary artery dissection: novel pathophysiological insights from histological and ultrastructural tissue analysis (2020) (0)
Large scale analysis of determinants of HDL efflux capacity (2014) (0)
Genetic and Transcriptomic Analysis of Chromosome 1 Blood Pressure QTL in the Spontaneously Hypertensive Rat: P95 (2006) (0)
Wednesday, 29 August 2012 (2012) (0)
Alcohol consumption and telomere length: observational and Mendelian randomization approaches (2021) (0)
55 Gene-gene interactions in coronary artery disease (2011) (0)
SVEP1 influences monocyte to macrophage differentiation via integrin α4β1/α9β1 and Rho/Rac signalling. (2023) (0)
70 Gene expression at the 9p21 locus and cad risk (2011) (0)
Response to the letter by Esteves et al. (2018) (0)
68 Rare alleles in genetic predisposition to coronary artery disease: insights from the novel analysis of gene-centric array (2011) (0)
Association analyses based on false discovery rate implicate 243 susceptibility loci for coronary artery disease (2017) (0)
OP-EHEA180728 4269..4276 (2018) (0)

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