Nina Papavasiliou
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Immunologist
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Nina Papavasilioubiology Degrees
Biology
#1313
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#2223
Historical Rank
Immunology
#570
World Rank
#589
Historical Rank
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Biology
Why Is Nina Papavasiliou Influential?
(Suggest an Edit or Addition)According to Wikipedia, Nina Papavasiliou is an immunologist and Helmholtz Professor in the Division of Immune Diversity at the German Cancer Research Center in Heidelberg, Germany. She is also an adjunct professor at the Rockefeller University, where she was previously associate professor and head of the Laboratory of Lymphocyte Biology. She is best known for her work in the fields of DNA and RNA editing.
Nina Papavasiliou's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing (2007) (3657)
- MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. (2008) (491)
- AID Mediates Hypermutation by Deaminating Single Stranded DNA (2003) (478)
- Cell-cycle-regulated DNA double-strand breaks in somatic hypermutation of immunoglobulin genes (2000) (293)
- Immunoglobulin somatic hypermutation. (2007) (280)
- Regulation of AID expression in the immune response (2007) (260)
- V(D)J recombination in mature B cells: a mechanism for altering antibody responses. (1997) (253)
- Somatic Hypermutation of Immunoglobulin Genes Merging Mechanisms for Genetic Diversity (2002) (219)
- Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3′ UTRs (2010) (219)
- V(D)J Recombination and the Evolution of the Adaptive Immune System (2003) (172)
- Antigen Receptor Engagement Turns off the V(D)J Recombination Machinery in Human Tonsil B Cells (1998) (149)
- The role of Ig beta in precursor B cell transition and allelic exclusion. (1995) (146)
- MicroRNAs of the immune system (2010) (141)
- The in vivo dynamics of antigenic variation in Trypanosoma brucei (2015) (130)
- The Activation-induced Deaminase Functions in a Postcleavage Step of the Somatic Hypermutation Process (2002) (123)
- Cytidine deaminases: AIDing DNA demethylation? (2010) (120)
- A coming-of-age story: activation-induced cytidine deaminase turns 10 (2009) (115)
- A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. (2006) (113)
- A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development (2011) (108)
- A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei (2009) (103)
- The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion (1995) (96)
- An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA (2007) (94)
- MicroRNA control of lymphocyte differentiation and function. (2011) (87)
- The Transcription Elongation Complex Directs Activation-Induced Cytidine Deaminase-Mediated DNA Deamination (2006) (80)
- DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID. (2015) (78)
- Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei (2016) (77)
- Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region (2009) (76)
- Secondary V(D)J recombination in B-1 cells (1999) (72)
- Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei (2012) (67)
- Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition [published erratum appears in J Exp Med 1997 Jan 6;185(1):183] (1996) (67)
- Shhh! Silencing by microRNA-155 (2009) (66)
- An endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei (2009) (57)
- Diverse functions for DNA and RNA editing in the immune system (2010) (54)
- Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation (2017) (53)
- Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NF-κB (2007) (52)
- Control of immunoglobulin gene rearrangements in developing B cells. (1997) (52)
- Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome (2015) (50)
- RNA Editors, Cofactors, and mRNA Targets: An Overview of the C-to-U RNA Editing Machinery and Its Implication in Human Disease (2018) (46)
- Pseudouridylation meets next-generation sequencing. (2016) (46)
- Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei (2016) (44)
- Beyond SHM and CSR: AID and related cytidine deaminases in the host response to viral infection. (2007) (43)
- African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat (2018) (42)
- Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase (2012) (42)
- RNA editing generates cellular subsets with diverse sequence within populations (2016) (40)
- A New Chapter in Genetic Medicine: RNA Editing and its Role in Disease Pathogenesis. (2018) (35)
- A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive (2016) (33)
- The regulation of somatic hypermutation. (2004) (32)
- Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology (2017) (31)
- Epitranscriptomic profiling across cell types reveals associations between APOBEC1-mediated RNA editing, gene expression outcomes, and cellular function (2017) (31)
- A comprehensive analysis of AID's effects on the transcriptome and methylome of activated B cells (2013) (29)
- Emerging challenges in understanding trypanosome antigenic variation (2017) (26)
- SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts (2021) (25)
- A Requirement for Argonaute 4 in Mammalian Antiviral Defense (2020) (22)
- C to U editing at position 32 of the anticodon loop precedes tRNA 5′ leader removal in trypanosomatids (2007) (22)
- MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition (2019) (20)
- A Single Zinc Ion Is Sufficient for an Active Trypanosoma brucei tRNA Editing Deaminase* (2011) (18)
- The C-terminal end of the Trypanosoma brucei editing deaminase plays a critical role in tRNA binding. (2011) (18)
- Mechanistic Similarities between Antigenic Variation and Antibody Diversification during Trypanosoma brucei Infection. (2019) (15)
- A Host-Pathogen Interaction Reduced to First Principles: Antigenic Variation in T. brucei. (2015) (15)
- Inducible Germline IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition. (2020) (15)
- Functional insights from a surface antigen mRNA-bound proteome (2021) (15)
- Structure of Trypanosome Coat Protein VSGsur and Function in Suramin Resistance (2021) (15)
- RAG expression in B cells in secondary lymphoid tissues. (1999) (13)
- Roles in inflammation and cancer (2010) (12)
- Rapid, adaptable and sensitive Cas13-based COVID-19 diagnostics using ADESSO (2022) (11)
- RNA Editing Dynamically Rewrites the Cancer Code. (2015) (10)
- Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs (2012) (10)
- Identifying mRNA editing deaminase targets by RNA-Seq. (2011) (9)
- Using T. brucei as a biological epitope-display platform to elicit specific antibody responses. (2010) (8)
- MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia (2017) (7)
- Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. (2021) (6)
- Vesicles as Vehicles for Virulence. (2016) (5)
- Immunodominant surface epitopes power immune evasion in the African trypanosome (2021) (5)
- Epigenetic Modulators of Monocytic Function: Implication for Steady State and Disease in the CNS (2016) (5)
- ADESSO detects SARS-CoV-2 and its variants: extensive clinical validation of an optimised CRISPR-Cas13-based COVID-19 test (2021) (3)
- APOBEC2 is a Transcriptional Repressor required for proper Myoblast Differentiation (2020) (3)
- Harnessing self-labeling enzymes for selective and concurrent A-to-I and C-to-U RNA base editing (2021) (3)
- Long noncoding RNAs: implications for antigen receptor diversification. (2009) (3)
- Dna deamination and the immune system: aid in health and disease (2010) (2)
- You break it, you fix it: functions for AID downstream of deamination (2013) (2)
- Acute expression of human APOBEC3B in mice causes lethality associated with RNA editing (2022) (2)
- Detection of Trypanosoma brucei Variant Surface Glycoprotein Switching by Magnetic Activated Cell Sorting and Flow Cytometry. (2016) (2)
- C-to-U RNA Editing: From Computational Detection to Experimental Validation. (2021) (2)
- It takes two (and some distance) to tango: how ADARs join to edit RNA (2020) (2)
- ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes (2020) (2)
- RNA Editors and DNA Mutators: Cancer Heterogeneity Through Sequence Diversification (2018) (1)
- Immunization with Genetically Modified Trypanosomes Provides Protection against Transmissible Spongiform Encephalopathies (2022) (1)
- The VEXing problem of monoallelic expression in the African trypanosome (2016) (1)
- A Modified Digestion‐Circularization PCR (DC‐PCR) Approach to Detect Hypermutation‐Associated DNA Double‐Strand Breaks (2003) (1)
- An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects (2022) (1)
- Transfer RNA Editing Enzymes; At the Crossroads of Affinity and Specificity (2007) (1)
- Nanobody Mediated Macromolecular Crowding Induces Membrane Fission and Remodeling in the African Trypanosome (2021) (1)
- RNA-Editing-Initiated MAVS Signaling is a Key Epitranscriptomic Alteration in Human B Cell Lymphoma (2021) (1)
- The regulation of somatic hypermutation: [Curr. Opin. Immunol. 16 (2004) 241] (2004) (1)
- Molecular Parasitology Meeting 2020: Virtually Everywhere and Anywhere (2020) (0)
- Neoepitope formation through the generation of RNA-derived “editopes” (2023) (0)
- Shhh ! Silencing by microRNA-155 Grace Teng and (2009) (0)
- Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome (2023) (0)
- RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE) (2022) (0)
- CYTIDINE DEAMINASES SHAPE THE GENOME OF GERMINAL CENTER B CELL DERIVED LYMPHOMA (2021) (0)
- ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes (2019) (0)
- Papavasiliou Cytidine deaminases : AIDing DNA demethylation ? (2010) (0)
- Variant surface glycoprotein density defines an immune evasion threshold for African trypanosomes undergoing antigenic variation (2017) (0)
- A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. (2023) (0)
- A Parasite Coat Protein Binds Suramin to Confer Drug Resistance (2020) (0)
- APOBEC2 binds Chromatin and Represses Transcription during Myoblast Differentiation (2020) (0)
- It takes two (and some distance) to tango: how ADARs join to edit RNA (2020) (0)
- Mu to Activate the Precursor B Cell Transit ion By Fotini Papavasiliou , Mila Jankovic (0)
- detects SARS-CoV-2 and its variants: extensive clinical validation of an optimised 2 CRISPR-Cas13-based COVID-19 test (2021) (0)
- Inducible Natural IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition (2019) (0)
- MicroRNA-155 Modulates Transforming Growth Factor-β Signaling In Chronic Lymphocytic Leukemia through Targeting of Casein Kinase γ Isoform 2 (2010) (0)
- Author response: Functional insights from a surface antigen mRNA-bound proteome (2021) (0)
- ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts (2023) (0)
- African Trypanosomes Can Evade Immune Clearance by Sugar-Coating Antigenic Surfaces (2018) (0)
- Decision letter: Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity (2021) (0)
- Faculty Opinions recommendation of Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. (2011) (0)
- Structural and Immunological Similarities Between the Metacyclic and Bloodstream Form Variant Surface Glycoproteins of the African Trypanosome (2022) (0)
- in Lymphocyte Development A Role for Autophagic Protein Beclin 1 Early (2011) (0)
- A Structural Classification of the Variant Surface Glycoproteins of the African Trypanosome (2023) (0)
- Title: Immunodominant surface epitopes power immune evasion in the 1 African trypanosome 2 (2022) (0)
- African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat (2018) (0)
- Genetic loss of the ubiquitin ligase RNF126, an AID interacting partner and modifier, affects strand targeting during somatic hypermutation of antibody genes (2018) (0)
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