Nir Hacohen

Nir Hacohen's AcademicInfluence.com Rankings

Nir Hacohen

Biology

#8457

World Rank

#11534

Historical Rank

Immunology

#485

World Rank

#502

Historical Rank

biology Degrees

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Biology

Nir Hacohen's Degrees

PhD Immunology Weizmann Institute of Science
Bachelors Biology Tel Aviv University

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Nir Hacohen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Full-length transcriptome assembly from RNA-Seq data without a reference genome. (2011) (12944)
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals (2009) (3820)
Trinity: reconstructing a full-length transcriptome without a genome from RNA-Seq data (2011) (3744)
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity (2015) (2443)
Rab27a and Rab27b control different steps of the exosome secretion pathway (2010) (1917)
An immunogenic personal neoantigen vaccine for patients with melanoma (2017) (1820)
A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen (2006) (1749)
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors (2017) (1554)
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling (2014) (1395)
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia (2012) (1297)
The Human Cell Atlas (2017) (1285)
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. (2011) (1098)
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells (2013) (1096)
B cells and tertiary lymphoid structures promote immunotherapy response (2020) (1046)
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma (2018) (981)
Single cell RNA Seq reveals dynamic paracrine control of cellular variation (2014) (848)
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. (2014) (836)
The plasticity of dendritic cell responses to pathogens and their components. (2001) (809)
Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. (2015) (773)
sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways (1998) (769)
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (754)
Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity (2010) (718)
A Physical and Regulatory Map of Host-Influenza Interactions Reveals Pathways in H1N1 Infection (2009) (654)
Landscape of X chromosome inactivation across human tissues (2016) (596)
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry (2018) (560)
Resistance to checkpoint blockade therapy through inactivation of antigen presentation (2017) (553)
Highly parallel identification of essential genes in cancer cells (2008) (553)
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. (1999) (539)
Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells (2011) (526)
Tumor necrosis factor-α suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: Nuclear factor-κB activation by TNF-α is obligatory (2002) (489)
Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses (2009) (483)
Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events. (1996) (479)
Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes (2014) (466)
Minimizing the risk of reporting false positives in large-scale RNAi screens (2006) (454)
Mass Spectrometry Profiling of HLA‐Associated Peptidomes in Mono‐allelic Cells Enables More Accurate Epitope Prediction (2017) (453)
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity (2020) (452)
Genome-scale loss-of-function screening with a lentiviral RNAi library (2006) (396)
1 Rab 27 a and Rab 27 b control different steps of the exosome secretion pathway (2009) (391)
Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells (2014) (383)
Dynamic profiling of the protein life cycle in response to pathogens (2015) (381)
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks (2015) (380)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (369)
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (368)
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. (2012) (367)
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets (2021) (347)
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis (2018) (304)
Mycobacterium tuberculosis protein ESAT‐6 is a potent activator of the NLRP3/ASC inflammasome (2010) (303)
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia. (2014) (302)
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia. (2014) (289)
Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. (1999) (281)
The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. (2009) (275)
Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics (2019) (271)
A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors (2016) (260)
Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory. (2002) (251)
Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36 (2009) (251)
Landscape of tumor-infiltrating T cell repertoire of human cancers (2016) (250)
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
A large peptidome dataset improves HLA class I epitope prediction across most of the human population (2019) (232)
Voltage dependence of adaptation and active bundle movement in bullfrog saccular hair cells. (1989) (228)
Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages. (2017) (227)
Intersection of population variation and autoimmunity genetics in human T cell activation (2014) (219)
Parsing the Interferon Transcriptional Network and Its Disease Associations (2016) (201)
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction (2020) (194)
Genome-wide enhancer maps link risk variants to disease genes (2021) (193)
Regulation of CD45 Alternative Splicing by Heterogeneous Ribonucleoprotein, hnRNPLL (2008) (191)
High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies (2014) (189)
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells (2016) (188)
Notch signaling drives synovial fibroblast identity and arthritis pathology (2020) (186)
In vivo discovery of immunotherapy targets in the tumour microenvironment (2014) (184)
Genetic control of epithelial tube fusion during Drosophila tracheal development. (1996) (183)
Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits (2011) (182)
Principles and Strategies for Developing Network Models in Cancer (2011) (181)
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance (2019) (181)
A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. (2015) (169)
An immune-cell signature of bacterial sepsis (2020) (169)
Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy. (2014) (169)
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma (2021) (168)
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. (2014) (167)
HLA-Binding Properties of Tumor Neoepitopes in Humans (2014) (165)
Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia (2012) (165)
Getting Personal with Neoantigen-Based Therapeutic Cancer Vaccines (2013) (160)
Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b (2011) (153)
Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition* (2012) (150)
Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system. (1996) (150)
B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. (2012) (148)
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma (2019) (145)
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma (2021) (140)
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs (2014) (124)
Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions (2021) (122)
Regulation of tension on hair-cell transduction channels: displacement and calcium dependence (1989) (119)
IAP inhibitors enhance co-stimulation to promote tumor immunity (2010) (119)
Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs (2002) (115)
Monitoring T cell–dendritic cell interactions in vivo by intercellular enzymatic labelling (2018) (112)
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. (2018) (111)
Spatially organized multicellular immune hubs in human colorectal cancer (2021) (109)
SF 3 B 1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia (2011) (106)
The scavenger receptor SCARF 1 mediates the clearance of apoptotic cells and prevents autoimmunity (103)
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection (2020) (98)
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade (2018) (97)
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection (2020) (95)
Synaptotagmin-mediated vesicle fusion regulates cell migration (2010) (95)
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach (2012) (94)
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling (2020) (94)
Systematic comparative analysis of single cell RNA-sequencing methods (2019) (93)
Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection (2020) (90)
Landscape of B cell immunity and related immune evasion in human cancers (2018) (88)
The scavenger receptor SCARF1 mediates apoptotic cell clearance and prevents autoimmunity (2013) (86)
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq (2020) (84)
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. (2015) (84)
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker. (2020) (83)
MyD88-Dependent TLR1/2 Signals Educate Dendritic Cells with Gut-Specific Imprinting Properties (2011) (81)
The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport (2018) (78)
RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. (2006) (78)
Carbohydrate‐Mediated Targeting of Antigen to Dendritic Cells Leads to Enhanced Presentation of Antigen to T Cells (2008) (75)
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer (2020) (74)
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. (2012) (71)
Erratum: Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma (Cell (2018) 175(4) (998–1013.e20), (S0092867418313941) (10.1016/j.cell.2018.10.038)) (2019) (70)
Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue (2018) (69)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells (2017) (69)
Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation (2019) (69)
Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion. (2014) (69)
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs (2021) (66)
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression (2018) (64)
Neoantigens encoded in the cancer genome. (2016) (63)
The lipogenic regulator SREBF2 induces Transferrin in circulating melanoma cells and suppresses ferroptosis. (2020) (61)
Systems Immunology: Learning the Rules of the Immune System. (2018) (59)
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription (2014) (58)
Positional specificity of different transcription factor classes within enhancers (2018) (58)
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer (2021) (58)
TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity (2015) (57)
The Human Cell Atlas White Paper (2018) (55)
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps (2021) (55)
Strategies to discover regulatory circuits of the mammalian immune system (2011) (55)
ImmVar project: Insights and design considerations for future studies of "healthy" immune variation. (2015) (55)
Rationale and design of the Kidney Precision Medicine Project. (2021) (50)
A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens. (2018) (47)
Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection (2017) (45)
GeNets: A unified web platform for network-based analyses of genomic data (2018) (43)
A Role for Toll-Like Receptor 4 in Dendritic Cell Activation and Cytolytic CD8+ T Cell Differentiation in Response to a Recombinant Heat Shock Fusion Protein1 (2004) (42)
Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells (2010) (42)
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli (2013) (42)
Early cross-coronavirus reactive signatures of humoral immunity against COVID-19 (2021) (42)
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro (2021) (39)
Forward RNAi screens in primary human hematopoietic stem/progenitor cells. (2009) (38)
The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection (2014) (38)
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses (2021) (37)
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients (2020) (37)
Radiation Therapy Enhances Immunotherapy Response in Microsatellite-stable Colorectal and Pancreatic Adenocarcinoma in a Phase II Trial (2021) (37)
Personal neoantigen cancer vaccines (2014) (37)
Integrated urine proteomics and renal single-cell genomics identify an interferon-γ response gradient in lupus nephritis. (2020) (35)
Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer (2020) (35)
RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels (2009) (35)
Flow Cytometry, Amped Up (2011) (35)
SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes (2021) (35)
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (2020) (34)
Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19 (2021) (34)
Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn’s disease (2019) (34)
Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory (2021) (32)
Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells* (2019) (31)
Human systems immunology: hypothesis-based modeling and unbiased data-driven approaches. (2013) (31)
Perturbation of m 6 AWriters Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 0 Sites (2014) (30)
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2 (2021) (30)
CD209a Expression on Dendritic Cells Is Critical for the Development of Pathogenic Th17 Cell Responses in Murine Schistosomiasis (2014) (30)
Immune receptor repertoires in pediatric and adult acute myeloid leukemia (2019) (28)
TGF-β Suppresses β-Catenin-Dependent Tolerogenic Activation Program in Dendritic Cells (2011) (27)
Simultaneous Profiling of Gene Expression and Chromatin Accessibility in Single Cells (2019) (26)
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes. (2021) (26)
A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies (2021) (26)
An eQTL landscape of kidney tissue in human nephrotic syndrome (2018) (25)
Systems biology approaches to dissect mammalian innate immunity. (2011) (25)
The Disabled homolog 2 controls pro-metastatic activity of tumor-associated macrophages. (2020) (24)
SO-26 Clinical efficacy of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients (2020) (24)
Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures (2019) (24)
Landscape of helper and regulatory antitumour CD4+ T cells in melanoma (2022) (23)
Notch signalling drives synovial fibroblast identity and arthritis pathology (2020) (22)
MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
A Role for Toll-Like Receptor 4 in Dendritic Cell Activation and Cytolytic CD8 T Cell Differentiation in Response to a Recombinant Heat Shock Fusion Protein (2004) (22)
Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans. (2011) (21)
An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling. (2017) (21)
Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma (2018) (20)
GeNets: a unified web platform for network-based genomic analyses (2018) (20)
Streamlined Protocol for Deep Proteomic Profiling of FAC-sorted Cells and Its Application to Freshly Isolated Murine Immune Cells. (2019) (19)
SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs (2020) (17)
Challenges and recommendations for epigenomics in precision health (2017) (17)
Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19 (2020) (15)
MAUDE: inferring expression changes in sorting-based CRISPR screens (2019) (15)
Personal Neoantigen Cancer Vaccines: A Road Not Fully Paved (2020) (14)
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease (2018) (14)
Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples (2021) (14)
A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network (2018) (14)
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer (2022) (14)
Targeting individual cells by barcode in pooled sequence libraries (2017) (14)
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy (2020) (14)
Semiconductor-based DNA sequencing of histone modification states (2013) (13)
High-throughput RNA isoform sequencing using programmable cDNA concatenation (2021) (13)
Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19 (2021) (13)
Plasma P-selectin is an early marker of thromboembolism in COVID-19 (2021) (13)
An shRNA-Based Screen of Splicing Regulators Identifies SFRS3 as a Negative Regulator of IL-1β Secretion (2011) (12)
Urine Proteomics and Renal Single‐Cell Transcriptomics Implicate Interleukin‐16 in Lupus Nephritis (2021) (12)
A unique subset of glycolytic tumor propagating cells drives squamous cell carcinoma (2021) (12)
Plasma P‐selectin is an early marker of thromboembolism in COVID‐19 (2021) (12)
Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma (2021) (12)
Genome-wide maps of enhancer regulation connect risk variants to disease genes (2020) (12)
Cumulus: a cloud-based data analysis framework for large-scale single-cell and single-nucleus RNA-seq (2019) (12)
Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019 (2021) (12)
SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint (2020) (12)
Fitness Landscape of Clonal Hematopoiesis Under Selective Pressure of Immune Checkpoint Blockade. (2020) (11)
How T cells spot tumour cells (2017) (11)
The immune cell landscape in kidneys of lupus nephritis patients (2018) (11)
Transcriptomic analysis and High dimensional phenotypic mapping of mononuclear phagocytes in mesenteric lymph nodes reveal differences between ulcerative colitis and Crohn's disease. (2019) (10)
Author response: The Human Cell Atlas (2017) (10)
Unbiased reconstruction of a mammalian transcriptional network mediating the differential response to pathogens (2009) (10)
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one (2016) (10)
Perturbation of m 6 A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 Sites Citation (2014) (9)
Vaccine serologic responses among transplant patients associate with COVID-19 infection and T peripheral helper cells (2021) (9)
Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade (2021) (9)
Accelerating Medicines Partnership: Organizational Structure and Preliminary Data From the Phase 1 Studies of Lupus Nephritis (2020) (9)
Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory (2021) (8)
RNAi screen for kinases and phosphatases that play a role in antigen presentation by dendritic cells (2012) (8)
Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance (2019) (8)
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells (2021) (7)
Corrigendum: Landscape of X chromosome inactivation across human tissues (2018) (7)
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry (2019) (7)
Functional screen of MSI 2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells (2017) (7)
Effect of dexamethasone in glioblastoma (GBM) patients on systemic and intratumoral T-cell responses induced by personalized neoantigen-targeting vaccine. (2018) (6)
Heavy Metal Enlightens Tumor Immunity (2017) (6)
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (6)
Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients (2022) (6)
Low protease activity in B cell follicles promotes retention of intact antigens after immunization (2023) (6)
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function (2016) (6)
Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients (2021) (5)
Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease (2021) (5)
Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity (2021) (5)
Integrative single cell and spatial transcriptomics of colorectal cancer reveals multicellular functional units that support tumor progression (2022) (5)
Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (5)
Targeting TBK1 to overcome resistance to cancer immunotherapy (2022) (5)
The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia (2022) (5)
Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution (2013) (4)
Single Cell Transcriptomics and Flow Cytometry Reveal Disease-associated Fibroblast Subsets in Rheumatoid Arthritis (2017) (4)
How T cells spot tumour cells. (2017) (4)
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial (2023) (4)
Impact of autoimmune risk alleles on the immune system (2015) (4)
High dimensional analyses of cells dissociated from cryopreserved synovial tissue (2018) (4)
Systematic Identification of Personal Mutated Tumor-Specific Neoantigens in CLL (2012) (3)
Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors (2021) (3)
Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens (2021) (3)
Application of a 27-protein candidate cardiovascular surrogate endpoint to track risk ascendancy and resolution in COVID-19. (2021) (3)
Alternative Splicing of the Inhibitory Immune Checkpoint Receptor SLAMF6 Generates a Dominant Positive Form, Boosting T-cell Effector Functions (2021) (3)
Publisher Correction: Landscape of B cell immunity and related immune evasion in human cancers (2019) (3)
Loss of the Nuclear Protein RTF2 Enhances Influenza Virus Replication (2020) (3)
Lysosomal DNaseII degrades nuclear DNA and prevents self DNA recognition (159.17) (2012) (3)
Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis (2019) (3)
Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer (2021) (2)
Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL (2010) (2)
An efficient lentiviral CRISPRi approach to silence genes in primary human monocytes (2020) (2)
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease. (2021) (2)
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (2020) (2)
Trajectories of Pulmonary Epithelial and Endothelial Injury Markers in COVID-19 Patients Requiring Respiratory Support at Presentation (2021) (2)
Human Dendritic Cells Common Genetic Variants Modulate Pathogen-Sensing Responses in (2014) (2)
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling (2023) (2)
Tumor Neoantigens Are Abundant Across Cancers (2013) (2)
Abstract A010: Personalized neoantigen-targeting vaccines for high-risk melanoma generate epitope spreading (2019) (2)
Abstract 4533: Plasma and exosome proteomic profiling for prediction of immunotherapy response and toxicity (2019) (2)
Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen (2023) (2)
Mo1106 – Immunologic Dissection of Colitis Related to Checkpoint Inhibitor Immunotherapy (2019) (2)
Distinct gene programs underpinning ‘disease tolerance’ and ‘resistance’ in influenza virus infection (2022) (2)
IRF3 inhibits IFN‐γ‐mediated restriction of intracellular pathogens in macrophages independently of IFNAR (2021) (2)
A cell-free antibody engineering platform rapidly generates SARS-CoV-2 neutralizing antibodies (2020) (2)
204 The immune cell landscape in kidneys of lupus nephritis patients (2019) (2)
Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL (2011) (1)
920 A single-cell spatially resolved MERFISH map of the colorectal tumor immune microenvironment (2021) (1)
Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade (2022) (1)
1830. Single-cell Transcriptional Profiling Reveals an Immune Cell State Signature of Bacterial Sepsis (2019) (1)
Some antibodies can dampen antiviral defences in people with severe COVID (2021) (1)
Detecting neoepitope-specific intra-tumoral T cell responses in a glioblastoma patient treated with personal neoantigen vaccine (2018) (1)
Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures (2011) (1)
Identifying Cell Type-Specific Chemokine Correlates with Hierarchical Signal Extraction from Single-Cell Transcriptomes. (2021) (1)
Integration of urine proteomics and renal single-cell genomics identifies an interferon-gamma response gradient in lupus nephritis. (2020) (1)
Liquid biopsy using plasma proteomic profiling to reveal predictors of immunotherapy response. (2019) (1)
Reconstructing a Genotype-Phenotype Map In Chronic Lymphocytic Leukemia (2013) (1)
Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1 (2011) (1)
150 Circulatory plasma proteomic biomarkers predict response to immunotherapy in melanoma patients and reveal biological insights into the tumor microenvironment (2022) (1)
Abstract 2030: A single-cell spatially resolved map of colorectal cancer identifies novel spatial relationships between cancer cells and the microenvironment (2022) (1)
Damaged DNA marching out of aging nucleus (2019) (1)
Abstract 566: Neoantigens from translated unannotated open reading frames in cancer (2019) (1)
Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer (2022) (1)
The use of plasma proteomic markers to understand the biology of immunotherapy response. (2020) (1)
655 Landscape of helper and regulatory CD4+ T cells in melanoma (2021) (1)
A unified web platform for network-based analyses of genomic data (2017) (1)
SLAMF6 deficiency augments tumor killing and skews towards an effector phenotype revealing it as a novel T cell checkpoint (2019) (1)
Optimized liquid and gas phase fractionation increase HLA-peptidome coverage for primary cell and tissue samples (2021) (1)
ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling (2022) (1)
Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis. (2023) (1)
Landscape of B cell immunity and related immune evasion in human cancers (2019) (1)
antileukemia responses to donor lymphocyte infusion Reversal of in situ T-cell exhaustion during effective human (2014) (1)
TRANSPLANTATION Systematic identi ﬁ cation of personal tumor-speci ﬁ c neoantigens in chronic lymphocytic leukemia (2014) (0)
318 SINGLE CELL DISSECTION OF THE TRANSCRIPTIONAL LANDSCAPE DEFINING CHECKPOINT INHIBITOR-ASSOCIATED COLITIS OPENS A WINDOW INTO IMMUNE DYSREGULATION IN THE HUMAN COLON (2020) (0)
Impact of autoimmune risk alleles on the immune system (2015) (0)
Localization and biophysical characterization of an adaptation mechanism in amphibian hair cells (1989) (0)
OR.37. shRNA Mediated Downregulation of Genes Identified as ‘Core Transcriptome’ in Murine T Regulatory Cells (2008) (0)
182: RENIN-ANGIOTENSIN SYSTEM MARKERS AND NONPULMONARY ORGAN INJURY IN SEVERE COVID-19 PNEUMONIA (2021) (0)
1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortium (2022) (0)
Abstract 6073: The lipogenic regulatorSREBPinducesTransferrinin circulating melanoma cells, suppressing their susceptibility to ferroptosis (2020) (0)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (0)
2002 Distinct intrarenal monocyte and macrophage populations differentiate into a common phagocytic state that is associated with histopathologic kidney injury in human lupus nephritis (2022) (0)
956 Spatial clustering reveals immune hub interaction with reservoir of stem-like CD8 T cells and predicts immunotherapy response in lung cancer patients (2022) (0)
Reply to Akin et al.: High Renin Concentrations in Severe COVID-19 Are Indicative for a Hypo–Renin–Angiotensin-System State (2022) (0)
Abstract 3013: Acquired resistance to immune checkpoint inhibition by melanoma phenotypic transformation (2019) (0)
Abstract B089: High-throughput profiling of HLA allele-specific peptides by MS for improved epitope prediction (2016) (0)
The immune cell landscape in kidneys of patients with lupus nephritis (2019) (0)
Abstract LB-179: Next-generation epitope prediction using mass spectrometry and integrative genomics (2017) (0)
Genetics, epigenetics, omics, biomarkers and personalised medicine in SLE and autoimmunity 262 UTILITY OF SERUM FERRITIN AS A MARKER OF DISEASE ACTIVITY IN CHILDHOOD SYSTEMIC LUPUS ERYTHEMATOSUS (2021) (0)
Investigating the tumor immune infiltrate for populations that predict immune-related adverse events (irAEs) in patients receiving PD-1 inhibitors. (2020) (0)
Radiation Induced Checkpoint Immunotherapy Response in Refractory Colorectal and Pancreatic Adenocarcinoma (2020) (0)
Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn’s disease (2019) (0)
Editorial overview: Cancer immunology: genomics & biomarkers: Cancer immunity through the prism of genomics and proteomics. (2016) (0)
In Brief (2001) (0)
Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response (2023) (0)
Clinical Implementation of Single-Cell RNA Sequencing Using Liver Fine Needle Aspirate Tissuesampling and Centralized Processing Captures Compartment Specific Immuno-Diversity (2021) (0)
ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS (2018) (0)
Microscale combinatorial stimulation of human myeloid cells reveals inflammatory priming by viral ligands (2023) (0)
Correction: Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn’s disease (2019) (0)
Macrophages from Rosa26-Integrated Cas9-Expressing C57BL/6J Mice Have a Putative TRIF-Mediated Defect in the TLR-3/4 Signaling (2021) (0)
Flt3, a New Regulator of IL-10 Production by Human T Cells, Identified Using an RNAi Library (2008) (0)
Multi‐modal Analysis and Modeling of Human Neurodegenerative Disease to Reveal Disease Mechanisms and Biomarkers (2022) (0)
Levels Cells Reveals FLT3 as a Modulator of IL-10 RNA Interference Screen in Primary Human T (2011) (0)
Serial T-cell Receptor (TCR) Repertoire Sequencing to Predict Outcomes in Gastrointestinal (GI) Malignancies (2020) (0)
Dendritic cell CD209a expression is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis (INC9P.443) (2014) (0)
An immune-cell signature of bacterial sepsis (2020) (0)
TD-07 Dissecting the role of myeloid cells in lupus nephritis (2018) (0)
Abstract LB197: An SU2C-Mark Foundation Lung collaborative update: integrative genomics identifies distinct transcriptional states associated with checkpoint blockade resistance (2021) (0)
Abstract IA35: Determinants of effective tumor immunity (2019) (0)
B cells and tertiary lymphoid structures promote immunotherapy response (2020) (0)
641 Spatially organized multicellular immune hubs in MMRd and MMRp colorectal cancer (2021) (0)
Multiplexed enrichment and genomic profiling of peripheral immune cell subsets on a microfluidic chip (2018) (0)
Towfique Raj Risk Alleles in Leukocytes Polarization of the Effects of Autoimmune and Neurodegenerative (2014) (0)
AB0167 SINGLE CELL RNA EXPRESSION IN LUPUS NEPHRITIS COMPARING AFRICAN-AMERICAN AND CAUCASIAN PATIENTS IDENTIFIES DIFFERENTIAL EXPRESSION OF TYPE I INTERFERON PATHWAY (2019) (0)
Abstract 3210: Strategies to improve the sensitivity and ranking ability of neoantigen prediction methods: Report on the results of the Tumor nEoantigen SeLection Alliance (TESLA) (2020) (0)
Systematic dissection of cytokine responses in vivo at single-cell resolution (2021) (0)
564 Single-cell transcriptomic analysis of immune compartments following combination immunotherapy treatment in poorly immunogenic tumors (2021) (0)
Abstract 3468: Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer (2023) (0)
Abstract SY11-04: Genetics of immune escape (2015) (0)
Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways (2019) (0)
Abstract B13: Integrative genomic and transcriptomic analysis of 775 human cancer cell lines reveals tumor-derived immune programs and their regulators (2017) (0)
Abstract IA13: RNA regulators and the control of self-renewal (2017) (0)
Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer. (2023) (0)
Abstract 5784: Spatial clustering reveals immune hub interaction with reservoir of stem-like CD8 T cells and predicts immunotherapy response in lung cancer patients (2023) (0)
Abstract 4072: Class I HLA-independent lysis of immunotherapy-resistant melanoma by CD8 T cells (2023) (0)
Identification of genes involved in unconventional protein secretion pathways (2009) (0)
Systematic profiling of HLA-C epitopes (2018) (0)
Abstract 5387: Novel targeted single-cell TCR sequencing method used for analysis of a T cell infiltrate from a glioblastoma patient (2018) (0)
Abstract LB003: Combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients: Correlative studies from a phase 2 trial (2022) (0)
Compositions and methods for identifying specific tumor neoantigens (2011) (0)
Abstract B016: Quantifying and dissecting pancreatic cancer cell phenotypic plasticity using lineage tracing, single-cell multiomics and CRISPR perturbations reveals novel regulators of plastic states (2022) (0)
Alternative splicing of SLAMF6 in human T cells creates a co-stimulatory isoform that counteracts the inhibitory effect of the full-length receptor (2020) (0)
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq (2020) (0)
Plasma P-selectin is an early marker of thromboembolism in COVID-19 (2023) (0)
Levels Cells Reveals FLT 3 as a Modulator of IL-10 RNA Interference Screen in Primary Human T Data (2009) (0)
Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. (2021) (0)
1242 Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define checkpoint inhibitor colitis (2022) (0)
1257 Single cell immunologic dissection of checkpoint inhibitor hepatitis and autoimmune hepatitis reveals insights into immune tolerance in the human liver (2022) (0)
Proximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+ T cell response (2022) (0)
Reversal of T Cell Exhaustion in Pre-Treatment Marrow T Cells Is Associated with Effective Graft-Versus-Leukemia Responses to Donor Lymphocyte Infusion (2012) (0)
Adaptation and Regulation of the Transduction Mechanism in Vestibular Hair Cells. (1988) (0)
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses. (2023) (0)
Kidney macrophages in human lupus nephritis and mouse models express conserved inflammatory and remodeling gene programs and localize to the same anatomic sub-compartments. (2021) (0)
Abstract A005: The aged tumor microenvironment influences tolerance to targeted therapy via NR2F1 overexpression in BRAF-mutant melanoma (2023) (0)
MAUDE: inferring expression changes in sorting-based CRISPR screens (2020) (0)
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis (2018) (0)
Clinical characteristics and molecular features of non-small cell lung cancers (NSCLCs) following disease progression on immune checkpoint inhibitors (ICIs). (2022) (0)
Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways (2019) (0)
205 Single cell RNA expression in lupus nephritis comparing african-american and caucasian patients identifies differential expression of type I interferon pathway (2019) (0)
Abstract LB-260: The use of blood-based protein biomarkers to uncover determinants of immunotherapy response in melanoma (2020) (0)
Immune receptor repertoires in pediatric and adult acute myeloid leukemia (2019) (0)
1 A cloning and expression system to probe T cell receptor specificity and assess functional avidity to neoantigens Running Head : Defining T cell receptor specificity to neoantigen (2018) (0)
Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (2020) (0)
Shock Fusion Protein Recombinant Differentiation in Response to a T Cell + Cell Activation and Cytolytic CD8 A Role for Toll-Like Receptor 4 in Dendritic (2004) (0)
Abstract 5902: Integrative genomic analysis of checkpoint blockade in lung cancer: A multi-institution SU2C collaborative (2020) (0)
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance (2019) (0)
MyD88-dependent TLR signals are necessary and sufficient to confer dendritic cells with gut-specific imprinting properties. (161.2) (2011) (0)
pattern cell migration and branching in the Drosophila tracheal Regulated Breathless receptor tyrosine kinase activity required to (2007) (0)
Characterizing the tumor and immune landscape of melanoma patients treated with combined checkpoint blockade and MAPK targeted therapy. (2021) (0)
264 Pearl: pathway exploration and analysis in renal disease in the accelerating medicine partnership (amp) lupus network (2017) (0)
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade (2023) (0)
Publisher Correction: Landscape of B cell immunity and related immune evasion in human cancers (2019) (0)
Vaccines Getting Personal with Neoantigen-Based Therapeutic Cancer (2013) (0)
Resistance to checkpoint blockade therapy through inactivation of antigen presentation (2017) (0)
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection (2020) (0)
HTAPP_Dissociation of human primary colorectal cancer resection specimens into single cell suspension for single cell RNA-seq v1 (2019) (0)
509 The localization of novel macrophage subsets in class III and IV lupus nephritis kidney sections (2021) (0)
Abstract 3580: Integrative genomics of checkpoint blockade response in advanced non-small cell lung cancer (2022) (0)
1112 Change in urinary biomarkers at three months predicts 1-year treatment response of lupus nephritisbetter than proteinuria (2022) (0)
Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq (2023) (0)
Unsupervised Protein-Ligand Binding Energy Prediction via Neural Euler's Rotation Equation (2023) (0)
HTAPP_Dissociation of human primary colorectal cancer resection specimens into single cell suspension for single cell RNA-seq v2 (2021) (0)
Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program (2014) (0)
IL-10 Levels T Cells Reveals FLT3 as a Modulator of RNA Interference Screen in Primary Human (2009) (0)
Author response: SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint (2020) (0)
IRF3 inhibits IFNγ-mediated restriction of intracellular pathogens in macrophages independently of type I interferons (2018) (0)
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy (2020) (0)
PropertiesDendritic Cells with Gut-Specific Imprinting MyD88-Dependent TLR1/2 Signals Educate (2011) (0)
Protocol for bulk RNA sequencing of enriched human neutrophils from whole blood and estimation of sample purity (2023) (0)
Abstract PR02: A personalized neoantigen vaccine in patients with high risk melanoma (2016) (0)
916 Acquired resistance to immune checkpoint blockade by phenotypic plasticity of melanoma (2022) (0)
A large peptidome dataset improves HLA class I epitope prediction across most of the human population (2019) (0)
Abstract C012: Dissecting the reorganization of pancreatic tumor microenvironments after radiation and immunotherapy reveals insights into immunotherapy resistance (2022) (0)
CeVICA selection protocol v1 (2021) (0)
Abstract 4488: Effector B cells and tertiary lymphoid structures predict response to immune checkpoint blockade in solid tumors (2019) (0)
Document S1. Six Figures, Three Tables, and Supplemental Experimental Procedures (2011) (0)
Increased T-cell receptor repertoire diversity to predict better overall survival in gastrointestinal malignancies. (2021) (0)
OR.80. Identifying Regulators of Cytokine Production in Primary Human T-Cells Using a Lentiviral RNAi Library (2006) (0)
RNAi screen of human primary T cells reveals FLT3 as a new regulator of IL-10 production (2008) (0)
1091 SINGLE CELL IMMUNOLOGIC DISSECTION OF HEPATITIS RELATED TO IMMUNE CHECKPOINT INHIBITOR THERAPY REVEALS INSIGHTS INTO IMMUNE TOLERANCE IN THE HUMAN LIVER (2020) (0)
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (0)
240 SINGLE-CELL RNA SEQUENCING REVEALS TRANSCRIPTIONAL SIGNATURES OF IMMUNE AND EPITHELIAL DYSREGULATION THAT DEFINE COLITIS ASSOCIATED WITH IMMUNE CHECKPOINT INHIBITORS (2021) (0)
Abstract 6670: Combined signals from tumor and immune cells predict outcomes of checkpoint inhibition in melanoma (2020) (0)
Abstract B042: Broad analysis and more accurate predictions of HLA class I epitope binding in 92 common HLA alleles profiled by mono-allelic mass spectrometry (2019) (0)
Genetic Control of Immune Variation across the Human Population (2015) (0)
SchistosomiasisTh17 Cell Responses in Murine Critical for the Development of Pathogenic CD209a Expression on Dendritic Cells Is (2014) (0)

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What Schools Are Affiliated With Nir Hacohen?

Nir Hacohen is affiliated with the following schools:

Weizmann Institute of Science
Tel Aviv University
Massachusetts Institute of Technology
University of California, San Francisco
Massachusetts General Hospital
Harvard University

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