Nobutaka Fujii

Q: What Schools Are Affiliated With Nobutaka Fujii

Nobutaka Fujii is affiliated with the following schools: Hokkaido University, University of Tokyo, Institute of Science Tokyo, Osaka University, Kyoto University

Nobutaka Fujii's AcademicInfluence.com Rankings

Nobutaka Fujii

Computer Science

#5807

World Rank

#6130

Historical Rank

Computational Linguistics

#887

World Rank

#900

Historical Rank

Machine Learning

#1678

World Rank

#1700

Historical Rank

Artificial Intelligence

#1913

World Rank

#1945

Historical Rank

computer-science Degrees

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Computer Science

Nobutaka Fujii's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Nobutaka Fujii's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 (2002) (1360)
Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5 (2004) (737)
The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. (2010) (733)
An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation. (1996) (659)
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function. (2000) (604)
Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. (2009) (467)
Molecular basis for membrane selectivity of an antimicrobial peptide, magainin 2. (1995) (406)
CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells. (2003) (351)
A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection (1997) (331)
Interactions of an antimicrobial peptide, magainin 2, with outer and inner membranes of Gram-negative bacteria. (1997) (326)
Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. (2005) (304)
Translocation of a channel-forming antimicrobial peptide, magainin 2, across lipid bilayers by forming a pore. (1995) (290)
HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus (2004) (287)
CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells (2005) (274)
Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers* (2005) (273)
Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells (2003) (273)
T140 analogs as CXCR4 antagonists identified as anti‐metastatic agents in the treatment of breast cancer (2003) (271)
Orientational and aggregational states of magainin 2 in phospholipid bilayers. (1994) (256)
CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells. (2007) (241)
A Point Mutation That Confers Constitutive Activity to CXCR4 Reveals That T140 Is an Inverse Agonist and That AMD3100 and ALX40-4C Are Weak Partial Agonists* (2002) (238)
The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor. (2001) (216)
A Role of CXC Chemokine Ligand 12/Stromal Cell-Derived Factor-1/Pre-B Cell Growth Stimulating Factor and Its Receptor CXCR4 in Fetal and Adult T Cell Development in Vivo (2003) (188)
Physicochemical determinants for the interactions of magainins 1 and 2 with acidic lipid bilayers. (1991) (183)
Elevated Serum Levels of Stromal-Derived Factor-1α Are Associated with Increased Osteoclast Activity and Osteolytic Bone Disease in Multiple Myeloma Patients (2005) (178)
CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer. (2004) (178)
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. (2003) (178)
Implanted Adult Human Dental Pulp Stem Cells Induce Endogenous Axon Guidance (2009) (173)
Magainin 1-induced leakage of entrapped calcein out of negatively-charged lipid vesicles. (1989) (166)
Anti-human immunodeficiency virus activity of a novel synthetic peptide, T22 ([Tyr-5,12, Lys-7]polyphemusin II): a possible inhibitor of virus-cell fusion (1992) (151)
Palladium-catalyzed sp(3) CH activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines. (2008) (150)
Modulation of magainin 2-lipid bilayer interactions by peptide charge. (1997) (149)
Remodeling of gp41-C34 peptide leads to highly effective inhibitors of the fusion of HIV-1 with target cells. (2002) (146)
Stromal cell‐derived factor 1‐mediated CXCR4 signaling in rat and human cortical neural progenitor cells (2004) (146)
Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes. (2011) (144)
Metastin and its variant forms suppress migration of pancreatic cancer cells. (2004) (141)
Identification of a CXCR4 antagonist, a T140 analog, as an anti‐rheumatoid arthritis agent (2004) (135)
Defensins inhibit HIV replication in vitro. (1993) (129)
Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns. (2006) (126)
Membrane permeabilization mechanisms of a cyclic antimicrobial peptide, tachyplesin I, and its linear analog. (1997) (122)
A highly stereoselective synthesis of (E)-alkene dipeptide isosteres via organocyanocopper-Lewis acid mediated reaction (1991) (121)
Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions. (2007) (121)
Palladium-catalyzed direct synthesis of carbazoles via one-pot N-arylation and oxidative biaryl coupling: synthesis and mechanistic study. (2009) (120)
Lipid Bilayer Simulations of CXCR4 with Inverse Agonists and Weak Partial Agonists* (2003) (112)
Gold‐Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl‐Annulated[a]carbazoles from Aniline‐Substituted Diethynylarenes (2010) (111)
New strategy for the chemical synthesis of proteins (1988) (111)
Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides. (2015) (110)
Calcitonin gene-related peptide increases in the dorsal root ganglia of adjuvant arthritic rat (1989) (108)
Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors. (2006) (103)
Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines. (2014) (99)
One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling. (2007) (97)
Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists. (2003) (93)
CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV. (2012) (91)
Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization. (2009) (91)
CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice. (2011) (91)
Gold-catalyzed hydroarylation of allenes: a highly regioselective carbon-carbon bond formation producing six-membered rings. (2007) (89)
Mutations Conferring Resistance to Human Immunodeficiency Virus Type 1 Fusion Inhibitors Are Restricted by gp41 and Rev-Responsive Element Functions (2005) (89)
Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins. (2005) (87)
Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis (2008) (86)
Trifluoromethanesulphonic acid, as a deprotecting reagent in peptide chemistry (1974) (86)
Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells (2010) (86)
Coiled-coil tag--probe system for quick labeling of membrane receptors in living cell. (2008) (86)
Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities. (2007) (84)
Gold(I)-catalyzed polycyclizations of polyenyne-type anilines based on hydroamination and consecutive hydroarylation cascade. (2011) (82)
The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains. (2010) (81)
Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines. (2010) (80)
The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model. (2006) (79)
Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. (2005) (79)
Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1. (2006) (78)
Cysteine-derived s-protected oxazolidinones: potential chemical devices for the preparation of peptide thioesters. (2006) (78)
Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands. (2011) (78)
Concise synthesis of indole-fused 1,4-diazepines through copper(I)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation. (2008) (77)
Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues. (2009) (77)
Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds. (2005) (76)
A Thermodynamic Preference of Chiral N-Methanesulfonyl and N-Arenesulfonyl 2,3-cis-3-Alkyl-2-Vinylaziridines over Their 2,3-Trans-Isomers: Useful Palladium(0)-Catalyzed Equilibration Reactions for the Synthesis of (E)-Alkene Dipeptide Isosteres (1997) (75)
Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation. (2015) (75)
Enantioselective total synthesis of (+)-lysergic acid, (+)-lysergol, and (+)-isolysergol by palladium-catalyzed domino cyclization of allenes bearing amino and bromoindolyl groups. (2011) (75)
SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide (2008) (74)
Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir. (2006) (72)
Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus) (2011) (72)
Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity. (1987) (71)
Studies on peptides. 103. Chemical synthesis of a crystalline protein with the full enzymic activity of ribonuclease A (1981) (71)
Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice. (2002) (70)
Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes. (2012) (70)
SmI2-Mediated Reduction of γ,γ-Difluoro-α,β-enoates with Application to the Synthesis of Functionalized (Z)-Fluoroalkene-Type Dipeptide Isosteres (2004) (68)
Thioredoxin-interacting protein suppresses bladder carcinogenesis. (2011) (68)
Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. (2006) (67)
The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury (2011) (67)
Stereoselective Synthesis of 2-Alkenylaziridines and 2-Alkenylazetidines by Palladium-Catalyzed Intramolecular Amination of α- and β-Amino Allenes (2001) (67)
Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides. (2007) (66)
Interactions of an antimicrobial peptide, tachyplesin I, with lipid membranes. (1991) (66)
Total synthesis of (+/-)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group. (2008) (66)
Targeted Disruption of the CXCL12/CXCR4 Axis Inhibits Osteolysis in a Murine Model of Myeloma‐Associated Bone Loss (2009) (66)
Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide. (2011) (64)
Transport Characteristics of a Novel Peptide Transporter 1 Substrate, Antihypotensive Drug Midodrine, and Its Amino Acid Derivatives (2006) (64)
Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors. (2011) (63)
Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. (2005) (63)
Application of dimethylsulphoxide(DMSO) / trifluoroacetic acid(TFA) oxidation to the synthesis of cystine-containing peptide (1991) (62)
Role of disulfide linkages in tachyplesin-lipid interactions. (1993) (61)
The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis (2005) (61)
Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo αvβ3 integrin related tumor imaging (2003) (61)
Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents. (2007) (61)
Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives. (2003) (59)
Interaction of human parathyroid hormone-related peptide with parathyroid hormone receptors in clonal rat osteosarcoma cells. (1988) (59)
Gold-catalyzed three-component annulation: efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones. (2012) (59)
A Novel Route to Diastereomerically Pure (E)-Alkene Dipeptide Isosteres from β-Aziridinyl-α,β-enoates by Treatment with Organocopper Reagents†‡ (1994) (58)
CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model (2012) (58)
Transition Metal-Catalyzed Intramolecular Cyclization of 1,5- and 1,6-Dienes via Direct Cleavage and Addition of the Carbon–Hydrogen Bond (1998) (58)
ASYMMETRIC INTRAMOLECULAR C-H/OLEFIN COUPLING : ASYMMETRIC CYCLIZATION REACTIONS OF 1,5-DIENES CATALYZED BY RHODIUM COMPLEXES (1997) (57)
The therapeutic potential of CXCR4 antagonists in the treatment of HIV (2003) (57)
Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling. (2007) (57)
Novel antiviral activity of bromocriptine against dengue virus replication. (2016) (57)
Binding sites of calcitonin gene-related peptide (CGRP): abundant occurrence in visceral organs. (1986) (57)
First Palladium-Catalyzed Aziridination Reaction of Amino Allenes. (1999) (56)
CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress (2016) (56)
Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres. (2010) (56)
A highly regio- and stereoselective formation of bicyclo[4.2.0]oct-5-ene derivatives through thermal intramolecular [2 + 2] cycloaddition of allenes. (2007) (56)
Rapid access to 3-(aminomethyl)isoquinoline-fused polycyclic compounds by copper-catalyzed four-component coupling, cascade cyclization, and oxidation. (2009) (55)
Electrostatically constrained alpha-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide. (2009) (54)
Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds. (2012) (54)
CXCR4 engagement promotes dendritic cell survival and maturation. (2007) (53)
Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats (2013) (53)
Effects of endothelin on microcirculation of the pancreas. (1992) (52)
Trimethylsilyl trifluoromethanesulphonate as a useful deprotecting reagent in both solution and solid phase peptide syntheses (1987) (52)
Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. (2010) (52)
Prognostic value of metastin expression in human pancreatic cancer (2009) (51)
Synthesis of potent β-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure–activity relationship studies (2003) (51)
Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase. (2008) (51)
Biological Activities of Homologous Loop Regions in the Laminin α Chain G Domains* (2003) (51)
Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists. (2010) (50)
Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity. (2008) (50)
Dual gold catalysis: synthesis of polycyclic compounds via C-H insertion of gold vinylidenes. (2014) (49)
Formal total synthesis of (+)-lysergic acid via zinc(II)-mediated regioselective ring-opening reduction of 2-alkynyl-3-indolyloxirane. (2011) (48)
Gold-Catalyzed Cascade Cyclization of 2-Alkynyl-N-Propargylanilines by Rearrangement of a Propargyl Group. (2015) (48)
Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure. (2006) (48)
Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors. (2007) (48)
Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates. (2010) (48)
Structure-activity relationship study on small peptidic GPR54 agonists. (2006) (48)
Indium-mediated atom-transfer and reductive radical cyclizations of iodoalkynes: synthesis and biological evaluation of HIV-protease inhibitors. (2004) (47)
Activation of Rho and Rho-Associated Kinase by GPR54 and KiSS1 Metastasis Suppressor Gene Product Induces Changes of Cell Morphology and Contributes to Apoptosis (2009) (47)
Enzyme immunoassay of a substance P-like immunoreactive substance in human plasma and saliva. (1990) (47)
Total synthesis of (-)-quinocarcin by gold(I)-catalyzed regioselective hydroamination. (2012) (47)
Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gαi activation. (2007) (46)
AZA-PAYNE REARRANGEMENT OF ACTIVATED 2-AZIRIDINEMETHANOLS AND 2,3-EPOXY AMINES UNDER BASIC CONDITIONS (1995) (46)
Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C. (2011) (46)
Facile synthesis of 1,2,3,4-tetrahydro-beta-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization. (2009) (45)
Silver trifluoromethanesulphonate as an S-deprotecting reagent for the synthesis of cystine peptides (1989) (45)
Cu(II)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group. (2009) (44)
Involvement of CD44 in induction of matrix metalloproteinases by a COOH-terminal heparin-binding fragment of fibronectin in human articular cartilage in culture. (2003) (44)
KiSS1 Metastasis Suppressor Gene Product Induces Suppression of Tyrosine Kinase Receptor Signaling to Akt, Tumor Necrosis Factor Family Ligand Expression, and Apoptosis (2009) (43)
Heptad Repeat-Derived Peptides Block Protease-Mediated Direct Entry from the Cell Surface of Severe Acute Respiratory Syndrome Coronavirus but Not Entry via the Endosomal Pathway (2007) (43)
Palladium(0)-Catalyzed Isomerization Reactions of Aziridines Bearing an alpha,beta-Unsaturated Ester Group: A Thermodynamic Preference for Chiral Alkyl (2E)-4,5-cis-4,5-Epimino-N-(alkyl- or arylsulfonyl) 2-Enoates over the Other Three Stereoisomers. (1997) (43)
Formal Total Synthesis of (±)-Strictamine Based on a Gold-Catalyzed Cyclization. (2016) (42)
Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. (2005) (41)
Stereoselective divergent synthesis of four diastereomers of pachastrissamine (jaspine B). (2010) (41)
Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic (2008) (41)
Synthesis and application of N-Boc-L-2-amino-4-(diethylphosphono)-4,4-difluorobutanoic acid for solid-phase synthesis of nonhydrolyzable phosphoserine peptide analogues (1995) (41)
Synthesis and Application of Fluorescein‐ and Biotin‐Labeled Molecular Probes for the Chemokine Receptor CXCR4 (2008) (40)
Design of Peptide-based Inhibitors for Human Immunodeficiency Virus Type 1 Strains Resistant to T-20* (2009) (40)
Induction of myogenic differentiation by SDF‐1 via CXCR4 and CXCR7 receptors (2010) (39)
Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of bromoallenes. (2009) (39)
Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation. (2008) (39)
Photolabile Protection for One‐Pot Sequential Native Chemical Ligation (2005) (39)
Stromal-Derived Factor 1 Signalling Regulates Radial and Tangential Migration in the Developing Cerebral Cortex (2007) (39)
Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis. (2007) (39)
Effects of synthetic human gastric inhibitory polypeptide on splanchnic circulation in dogs. (1988) (38)
Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics. (2002) (38)
Molecular modeling study of cyclic pentapeptide CXCR4 antagonists: new insight into CXCR4-FC131 interactions. (2012) (38)
Resistance Profiles of Novel Electrostatically Constrained HIV-1 Fusion Inhibitors* (2010) (38)
Studies on Peptides. XLVIII. Application of the Trifluoromethanesulphonic Acid Procedure to the Synthesis of Tuftsin (1975) (38)
Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows (2013) (38)
Zipper-mode double C-H activation: palladium-catalyzed direct construction of highly-fused heterocyclic systems. (2007) (37)
Syn-SN2′ Pathway in the Reaction of Certain γ-(Mesyloxy) α, β-Enoates with RCu(CN)MgX×BF3 Reagents. Importance of MgX and Bulky R Group upon the Diastereoselectivity. (1993) (37)
Optimized method of G-protein-coupled receptor homology modeling: its application to the discovery of novel CXCR7 ligands. (2013) (36)
Clinical significance of plasma metastin level in pancreatic cancer patients. (2009) (36)
Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. (2005) (35)
Synthesis of optically pure 2-aziridinemethanols: versatile synthetic building blocks (1994) (35)
Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors. (2009) (35)
GPR54 Is a Target for Suppression of Metastasis in Endometrial Cancer (2011) (35)
New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under ‘reduction–oxidative alkylation (R–OA)’ conditions (2001) (34)
Potent CXCR4 antagonists containing amidine type Peptide bond isosteres. (2011) (34)
Synthesis of (Z)-fluoroalkene dipeptide isosteres utilizing organocopper-mediated reduction of γ,γ-difluoro-α,β-enoates (2001) (34)
Studies on peptides. L. Acidolysis of protecting groups in peptide chemistry by fluorosulphonic acid and methanesulphonic acid. (1975) (34)
Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes. (2015) (33)
Micro-enzyme immunoassay of vasoactive intestinal polypeptide (VIP)-like immunoreactive substance in bovine milk. (1990) (33)
Fluorescent imaging of high‐grade bladder cancer using a specific antagonist for chemokine receptor CXCR4 (2009) (33)
Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group. (2015) (33)
Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains. (2003) (33)
Transition Metal-Catalyzed Intramolecular C-H/Olefin Coupling. (1997) (33)
Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs. (2006) (32)
Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides (2006) (32)
Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization. (2009) (32)
Indium-mediated atom-transfer cyclizations and reductive cyclizations (2002) (32)
Potent Synergistic Anti-Human Immunodeficiency Virus (HIV) Effects Using Combinations of the CCR5 Inhibitor Aplaviroc with Other Anti-HIV Drugs (2008) (32)
Heck-type cyclization of oxime ethers: stereoselective carbon-carbon bond formation with aryl halides to produce heterocyclic oximes. (2007) (31)
SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54. (2007) (31)
Bromoallenes as allyl dication equivalents in the presence or absence of palladium(0): direct construction of bicyclic sulfamides containing five- to eight-membered rings by tandem cyclization of bromoallenes. (2007) (31)
Unprecedented rearrangement reaction of 2-aziridinemethanols with “lower order” lithium methylcyanocuprate (1993) (31)
Biological activities of homologous loop regions in the laminin alpha chain G domains. (2003) (31)
Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by S(N)Ar-type C-S, C-N, or C-O bond formation with heterocumulenes. (2010) (31)
Stromal Cell-Derived Factor 1 Regulates the Actin Organization of Chondrocytes and Chondrocyte Hypertrophy (2012) (30)
Enzyme immunoassay of somatostatin (SS)-like immunoreactive substance in bovine milk. (1990) (30)
Potassium carbonate-promoted stereospecific 5-endo-trig cyclization of unactivated allenes in the absence of any transition metals. (2006) (30)
Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists. (2006) (30)
Disulfide bond formation in S-Acetamidomethyl cysteine-containing peptides by the combination of silver trifluoromethanesulfonate and dimethylsulfoxide / aqueous HCl (1993) (30)
Structure-activity relationship study of a CXC chemokine receptor type 4 antagonist, FC131, using a series of alkene dipeptide isosteres. (2012) (29)
Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach. (2008) (29)
Double C-H functionalization in sequential order: direct synthesis of polycyclic compounds by a palladium-catalyzed C-H alkenylation-arylation cascade. (2012) (29)
SN2′ Ring opening of aziridines bearing an α,β-unsaturated ester group with organocopper reagents. A new stereoselective synthetic route to (E)-alkene dipeptide isosteres (1995) (28)
Direct construction of bicyclic heterocycles by palladium-catalyzed domino cyclization of propargyl bromides. (2008) (28)
CXCR 4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer (2004) (28)
Highly Selective Synthesis of (E)‐Alkene Isosteric Dipeptides With High Optical Purity via RCu(CN)Li·BF3 Mediated Reaction (1990) (28)
Stereoselective Synthesis of Chiral Amino Allenes by Organocopper-Mediated anti-SN2′-Substitution Reaction of Chiral Ethynylaziridines (2000) (27)
Synthesis of fluoroalkene dipeptide isosteres by an intramolecular redox reaction utilizing N-heteorocyclic carbenes (NHCs). (2009) (27)
CXCL 12 expression by invasive trophoblasts induces the specific migration of CD 16 human natural killer cells (2003) (27)
Odoamide, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Okeania sp. (2016) (27)
SYNTHESIS OF CHIRAL AMINO ALLENES VIA AN ORGANOCYANOCUPRATE-MEDIATED RING-OPENING REACTION OF ENANTIOPURE ETHYNYLAZIRIDINES (1999) (27)
Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation. (2014) (27)
Reactions of N-Arylsulfonyl-2,3-cis- and N-Arylsulfonyl-2,3-trans-3-alkyl-2-vinylaziridines with Organocopper Reagents: Importance of 2,3-cis-Stereochemistry in Controlling Regio- and Stereoselectivity. (1998) (27)
Convenient syntheses of chiral 3-substituted 2-ethynylaziridines (1999) (26)
Palladium-catalyzed regio- and stereoselective synthesis of N-protected 2,4-dialkylated azacyclobutanes from amino allenes (1999) (26)
Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes (2011) (26)
Asymmetric synthesis of β2,3-amino acids by InI–Pd(0)-promoted metalation and addition of chiral 2-vinylaziridines (2002) (26)
Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres. (2007) (26)
Isolation and characterization of a tumor-derived human protein related to chromogranin A and its in vitro conversion to human pancreastatin-48. (1990) (25)
Development of new methodology for the synthesis of functionalized α-fluorophosphonates and its practical application to the preparation of phosphopeptide mimetics (2000) (25)
Structure‐activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists (2008) (25)
Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system. (2002) (25)
New procedure for the synthesis of cystine-peptides by oxidation of S-substituted cysteine-peptides with thallium(III) trifluoroacetate (1987) (25)
Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations. (2006) (25)
Facile synthesis of membrane-embedded peptides utilizing lipid bilayer-assisted chemical ligation. (2004) (24)
Physical association of GPR54 C-terminal with protein phosphatase 2A. (2008) (24)
Role of methionine in the facilitated cleavage of aromatic ethers by methanesulphonic acid (1976) (24)
CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner (2016) (24)
Totally synthetic crystalline ribonuclease A (1981) (24)
Regio- and stereoselectivity in reactions of 2,3-cis- and trans-3-alkyl-2-vinylaziridines with organocopper reagents: Importance of 2,3-cis-stereochemistry in controlling selectivity (1997) (24)
Studies on Peptides. CLXVIII. : Syntheses of Three Peptides Isolated from Horseshoe Crab Hemocytes, Tachyplesin I, Tachyplesin II, and Polyphemusin I (1989) (24)
Wurster's Blue-type cation radicals framed in a 5,10-dihydrobenzo[a]indolo[2,3-c]carbazole (BIC) skeleton: dual electrochromism with drastic changes in UV/Vis/NIR and fluorescence. (2014) (24)
siRNA delivery into tumor cells by cationic cholesterol derivative-based nanoparticles and liposomes. (2015) (24)
Application of samarium diiodide (SmI2)-induced reduction of γ-acetoxy-α,β-enoates with α-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives (2003) (23)
Development of Efficient Two-Step Deprotection Methodology for Dimethyl-Protected Phosphoamino Acid-Containing Peptide Resins and Its Application to the Practical Synthesis of Phosphopeptides (1995) (23)
Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors. (2013) (23)
Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist. (2012) (23)
Affinity purification method using a reversible biotinylating reagent for peptides synthesized by the solid-phase technique (1993) (23)
Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents. (2012) (23)
Identification of minimal sequence for HIV-1 fusion inhibitors. (2008) (23)
Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis (2013) (23)
Chemoselective one-step purification method for peptides synthesized by the solid-phase technique. (1991) (22)
Regio- and Stereoselective Synthesis of (E)-Alkene trans-Xaa-Pro Dipeptide Mimetics Utilizing Organocopper-Mediated Anti-SN2‘ Reactions (2002) (22)
Stereoselective synthesis of nonracemic 1,3-amino alcohols from chiral 2-vinylaziridines by InI–Pd(0)-promoted metalation (2001) (22)
HIV‐1 gp120 enhances outward potassium current via CXCR4 and cAMP‐dependent protein kinase a signaling in cultured rat microglia (2011) (22)
Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4). (2012) (22)
Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide. (2009) (22)
A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L-cysteine, a novel Eg5 inhibitor. (2011) (22)
Construction of linked nitrogen heterocycles by palladium(0)-catalyzed intramolecular domino cyclization of 2-alkynylaziridines bearing a 2-aminoethyl group via ring expansion with isocyanate. (2010) (22)
siRNA delivery into tumor cells by lipid-based nanoparticles composed of hydroxyethylated cholesteryl triamine. (2013) (22)
Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: The insertion of an (E)-alkene dipeptide isostere into the βII′-turn moiety (2002) (22)
5,10-Dihydrobenzo[a]indolo[2,3-c]carbazole: A Highly Fluorescent Disk-shaped Electron Donor Exhibiting Dual UV–vis–NIR and Fluorescence Spectral Changes upon Electrolysis (2013) (22)
Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016 (2012) (22)
Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles. (2012) (22)
A Small Molecule CXCR 4 Inhibitor that Blocks T Cell Line – tropic HIV-1 Infection (1997) (21)
Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells. (2008) (21)
Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors. (2016) (21)
Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne. (2016) (21)
Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates. (2008) (21)
Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists. (2007) (21)
Regiospecific ring-opening reactions of β-aziridinyl α,β-enoates with acids: application to the stereoselective synthesis of a couple of diastereoisomeric (E)-alkene dipeptide isosteres from a single β-aziridinyl α,β-enoate and to the convenient preparation of amino alcohols bearing α,β-unsaturated (2000) (21)
A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres. (2006) (21)
New synthesis of isoquinoline alkaloids, thalifoline, corypalline, and cherylline. (1980) (21)
Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade. (2008) (21)
Human calcitonin gene-related peptide possesses weak inhibitory potency of bone resorptionin vitro (1986) (21)
Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. (2014) (20)
Convergent synthesis of (-)-quinocarcin based on the combination of Sonogashira coupling and gold(I)-catalyzed 6-endo-dig hydroamination. (2013) (20)
HIV‐1 gp120 enhances giant depolarizing potentials via chemokine receptor CXCR4 in neonatal rat hippocampus (2006) (20)
Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors. (2015) (20)
Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles. (2012) (20)
Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants. (2015) (19)
A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor. (2010) (19)
The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases (2011) (19)
Purification of a novel type of calcium-activated neutral protease from rat brain. Possible involvement in production of the neuropeptide kyotorphin from calpastatin fragments. (1990) (19)
Structure-activity relationship study on polyglutamine binding peptide QBP1. (2009) (19)
Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore. (2008) (19)
SN2′ selective alkylation of allylic chlorides and mesylates with RZnX reagents generated from Grignard reagents, zinc chloride, lithium chloride, and Cu(II)-salts (1993) (18)
Studies on Peptides. LXIX. Selective Removal of Acid Labile α-Amino Protecting Groups with Dilute Sulfonic Acids (1977) (18)
Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility. (2014) (18)
Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. (2009) (18)
Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study. (2002) (18)
Association of Nucleophosmin Negatively Regulates CXCR4-Mediated G Protein Activation and Chemotaxis (2007) (18)
The chemokine receptor CXCR4 as a therapeutic target for several diseases. (2005) (18)
Design and synthesis of amidine-type peptide bond isosteres: application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis. (2011) (17)
Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A. (2015) (17)
Stereoselective synthesis of (Z)-alkene-containing proline dipeptide mimetics. (2006) (17)
Studies on Peptides. CXXXII. : Evaluation of Two β-Carboxyl Protecting Groups of Aspartic Acid, Cycloheptyl and Cyclooctyl, for Peptide Synthesis (1986) (17)
Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents. (2013) (17)
Structure‐Activity Relationships of Pyrazine‐Based CK2 Inhibitors: Synthesis and Evaluation of 2,6‐Disubstituted Pyrazines and 4,6‐Disubstituted Pyrimidines (2008) (17)
Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides. (2004) (17)
Development of anti-HIV agents targeting dynamic supramolecular mechanism: entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides. (2005) (17)
Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists. (2009) (16)
A convenient synthesis of activated enantiomerically pure 2-ethynylaziridines (1998) (16)
X-ray crystallographic study of an HIV-1 fusion inhibitor with the gp41 S138A substitution. (2009) (16)
Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP). (2016) (16)
Total synthesis of bovine pancreatic ribonuclease A. Part 6. Synthesis of RNase A with full enzymic activity (1981) (16)
Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper-mediated S(N)2' alkylation. (2009) (16)
Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182. (2013) (16)
Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold. (2015) (16)
Peptide-lead CXCR4 antagonists with high anti-HIV activity. (2001) (16)
Combination of a new amide-precursor reagent and trimethylsilyl bromide deprotection for the Fmoc-based solid phase synthesis of human pancreastatin and one of its fragments (Fmoc = fluoren-9-ylmethoxycarbonyl) (1988) (16)
Highly potent anti-HIV-1 activity isolated from fermented Polygonum tinctorium Aiton (2005) (16)
Synthesis of fluorine-containing bioisosteres corresponding to phosphoamino acids and dipeptide units. (2004) (15)
Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold. (2015) (15)
Palladium-catalyzed reductive ring opening with formic acid of aziridines bearing an α,β-unsaturated ester group (1997) (15)
Synthesis of fused and linked bicyclic nitrogen heterocycles by palladium-catalyzed domino cyclization of propargyl bromides. (2010) (15)
Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. (2005) (15)
Syntheses and Biological Activities of Selenium Analogs of α-Rat Atrial Natriuretic Peptide (1993) (15)
Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin (2007) (15)
Effect of synthetic neuromedin C, a decapeptide of gastrin-releasing peptide (GRP [18-27]), on blood flow and exocrine secretion of the pancreas in dogs. (1985) (15)
Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat. (2010) (15)
A modified benzhydrylamine as a handle reagent for the solid phase synthesis of peptide amides based on the fluorenylmethoxycarbonyl method (1988) (15)
Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu (2001) (15)
Chemical synthesis of bovine pancreatic ribonuclease A (1980) (15)
An aza-Payne rearrangement-epoxide ring opening reaction of 2-aziridinemethanols in a one-pot manner: A regio- and stereoselective synthetic route to diastereomerically pure N-protected 1,2-amino alcohols (1996) (15)
Topochemical exploration of potent compounds using retro-enantiomer libraries of cyclic pentapeptides. (2004) (15)
A one-pot aza-Payne rearrangement-epoxide ring opening reaction of 2-aziridinemethanols: A regio- and stereoselective synthetic route to diastereomerically pure 1,2-amino alcohols (1995) (15)
GXXXG-Mediated Parallel and Antiparallel Dimerization of Transmembrane Helices and Its Inhibition by Cholesterol: Single-Pair FRET and 2D IR Studies. (2017) (15)
Sterically congested chiral activated aziridines: Synthesis of both 2,3-cis- and 2,3-trans-2-alkenyl-3-alkylaziridines from common intermediates (1999) (15)
Total synthesis of odoamide, a novel cyclic depsipeptide, from an Okinawan marine cyanobacterium. (2016) (14)
Studies on Peptides. LXXIV. Convenient Procedure for the Preparation of Methionine Sulphoxide Derivatives (1978) (14)
Studies on Peptides. LXXIII. Examination of the Methanesulphonic Acid Procedure for the Synthesis of Peptides containing Methionine (1977) (14)
Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress. (2014) (14)
Corrigendum to “conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity”: [Bioorg. Med. Chem. Lett. 11 (2001) 359] (2001) (14)
Peptide and Peptidomimetic Ligands for CXC Chemokine Receptor 4 (CXCR4) (2012) (14)
Modulation of Network-Driven, GABA-Mediated Giant Depolarizing Potentials by SDF-1α in the Developing Hippocampus (2007) (14)
Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors. (2013) (14)
Novel synthesis of chiral terminal allenes via palladium(0)-catalyzed reduction of mesylates of 2-bromoalk-2-en-1-ols bearing a protected amino group, using diethylzinc (2000) (14)
Concise site-specific synthesis of DTPA-peptide conjugates: application to imaging probes for the chemokine receptor CXCR4. (2011) (13)
Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes. (2013) (13)
Total synthesis of bovine pancreatic ribonuclease A. Part 3. Synthesis of the protected hexapentacontapeptide ester (positions 69–124) (1981) (13)
Convenient one-pot synthesis of cystine-containing peptides using the trimethylsilyl chloride–dimethyl sulfoxide/trifluoroacetic acid system and its application to the synthesis of bifunctional anti-HIV compounds1 (1998) (13)
Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization (2012) (12)
Studies on Peptides. LXXXIII. Behavior of S-Substituted Cysteine Sulfoxides under Deprotecting Conditions in Peptide Synthesis (1979) (12)
A modified benzhydrylamine - A useful handle reagent for Fmoc based solid phase synthesis of peptide amides (1988) (12)
“Higher order” zinc cuprates involving lithium chloride: Synthesis of (E)-alkene dipeptide isosteres free from reductive elimination products (1992) (12)
Studies on peptides. CLX. Synthesis of a 33-residue peptide corresponding to the entire amino acid sequence of human cholecystokinin (hCCK-33). (1988) (12)
Role of CXCR4 and SDF-1 in mammary tumor metastasis in the cat. (2003) (12)
Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems. (2017) (12)
Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats. (2019) (12)
Head-to-tail macrocyclization of cysteine-free peptides using an o-aminoanilide linker. (2018) (11)
A simple, Automated Quasi‐4D‐QSAR, Quasi‐multi Way PLS Approach to Develop Highly Predictive QSAR Models for Highly Flexible CXCR4 Inhibitor Cyclic Pentapeptide Ligands Using Scripted Common Molecular Modeling Tools (2005) (11)
Permeabilization and morphological changes in phosphatidylglycerol bilayers induced by an antimicrobial peptide, tachyplesin I (1993) (11)
Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds. (2015) (11)
Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein. (2009) (11)
An unusual thermodynamic preference of chiral N-arylsulfonyl cis-3-alkyl-2-vinylaziridines over their trans-isomers: palladium(0)-catalysed equilibration reactions (1996) (11)
Studies on peptides. CLXV.1,2) Combination of a new amide-precursor reagent and trimethylsilyl bromide deprotection for the 9-fluorenylmethyloxycarbonyl-based solid-phase synthesis of chicken antral peptide. (1988) (11)
Synthesis of IB-01212 by multiple N-methylations of peptide bonds. (2014) (10)
Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread. (2015) (10)
Regioselective cleavage of aromatic methyl ethers by methanesulphonic acid in the presence of methionine (1977) (10)
A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats. (2012) (10)
Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: synthetic study of laurendecumallene B. (2013) (10)
Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-SN2′ reactions (2005) (10)
Studies on peptides. CXXXIV. Evaluation of S-1-adamantylcysteine for peptide synthesis. (1986) (10)
A thermodynamic preference of chiral cis-γ,δ-epimino-(E)-α,β-unsaturated esters over other stereoisomers: Synthetically useful Pd(0)-catalyzed equilibrated reactions of aziridines bearing an α,β-unsaturated ester group (1996) (10)
Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres (2002) (10)
Stereodivergent synthesis of chiral 2-alkenylaziridines: palladium(0)-catalyzed 2,3-cis-selective aziridination and base-mediated 2,3-trans-selective aziridination. (2004) (10)
Diastereoselective synthesis of psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]- type dipeptide isosteres based on organocopper-mediated anti-S(N)2' reaction. (2002) (10)
Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors (2016) (10)
Selective synthesis of cis-2-vinyl-3-alkylaziridines and 3-pyrrolines from common intermediates (Z)-4-N-arylsulfonylaminoalk-2-en-1-ols (1999) (10)
Erratum: The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model (Haematologica (2006) 91, (605-12)) (2007) (10)
Studies on peptides. LXXII. Examination of the N.EPSILON.-alkylation of lysine in the methanesulphonic acid procedure for peptide synthesis. (1977) (10)
Diastereoselective synthesis of psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type dipeptide isosteres by organocopper-mediated anti-S(N)2' reaction. (2002) (9)
Induction of human leukocyte antigen (HLA)‐A2‐restricted and MAGE‐3‐gene‐derived peptide‐specific cytolytic T lymphocytes using cultured dendritic cells from an HLA‐A2 esophageal cancer patient (1999) (9)
A Novel Oxazolidine Linker for the Synthesis of Peptide Aldehydes (2007) (9)
A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo (2016) (9)
The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7 (2010) (8)
Molecular Size of an Anti-HIV Peptide, T22, Can Be Reduced without Loss of the Activity (1996) (8)
Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging. (2003) (8)
(E)-stereoselective synthesis of vinylglycines from (R)-serine via organocopper–BF3 and related reagents (1994) (8)
Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats (2020) (8)
Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins. (2009) (8)
Synthesis of galanin, a new gastrointestinal polypeptide (1985) (8)
Palladium-Catalyzed Construction of Polycyclic Heterocycles by an Alkyne Insertion and Direct Arylation Cascade (2011) (8)
Remarkable difference in reactivity of ordinary vinylcopper reagents and vinylzinc halide containing a copper salt towards γ-mesyloxy-α, β-enoates. Synthesis of homochiral 1,4-dienes (1993) (8)
Screening of a virtual mirror-image library of natural products. (2016) (8)
Susceptibility of diverse primary HIV isolates with varying co‐receptor specificity's to CXCR4 antagonistic compounds (2002) (8)
S-benzyloxymethylcysteine, its properties and application in the synthesis of porcine brain natriuretic peptide (pBNP) (1989) (8)
Development of novel NK3 receptor antagonists with reduced environmental impact. (2016) (8)
Sulphoxide-directed disulphide bond-forming reaction for the synthesis of cystine peptides (1987) (8)
Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group. (2009) (8)
Studies on Peptides. XCIV. Thiazoline-2-thione as a Carboxyl-activating Reagent for Petide Synthesis (1980) (8)
Versatile use of acid-catalyzed ring-opening of β-aziridinyl-α,β-enoates to stereoselective synthesis of peptidomimetics (2007) (8)
Determination of absolute configuration of the alkyl group at the α-position in the acyclic α-alkyl-(E)-β,γ-enoates by circular dichroism (1990) (8)
Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists. (2012) (8)
Development of copper-mediated allylation of γ-activated-α,β-unsaturated lactam toward peptide mimetic synthesis (2007) (8)
Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure-activity relationship study of 4-epi-jaspine B. (2017) (8)
A Cisplatin Derivative that Inhibits Collagen Fibril‐Formation in vitro (2015) (8)
Synthesis of (Z)-alkene-containing cis-proline dipeptide mimetics using samarium(II) diiodide (SmI2)-mediated reductive alkylation reaction (2007) (8)
A 2,3-cis-selective synthesis of aziridines bearing a vinyl group from allyl methyl carbonates and allyl mesylates (1998) (7)
Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus. (2009) (7)
Two orthogonal approaches to overcome multi-drug resistant HIV-1s: development of protease inhibitors and entry inhibitors based on CXCR4 antagonists. (2004) (7)
Concise Synthesis of Indole-Fused 1,4-Diazepines Through Copper(I)-Catalyzed Domino Three-Component Coupling—Cyclization—N-Arylation under Microwave Irradiation. (2008) (7)
Apparent Autolysis of the N-Terminal Tetrapeptide of Vasoactive Intesinal polypeptide (VIP) (1983) (7)
A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging. (2014) (7)
Structure-Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide-Polyketides. (2018) (7)
Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists. (2013) (7)
A NEW SYNTHESIS OF THE CENTRAL SUBSTRUCTURE OF BOTRYOCOCCENES (1998) (7)
Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-β signaling modulators from Streptomyces sp. (2015) (7)
Receptor binding of cholecystokinin analogues in isolated rat pancreatic acini. (1990) (7)
Behaviour of S-substituted cysteine sulfoxide under acidolytical deprotecting conditions. (1979) (7)
Studies on Peptides. XCVI. Behavior of S-Acetamidomethylcysteine Sulfoxide under Deprotecting Conditions in Peptide Synthesis (1980) (6)
Studies on peptides CLVIII. Model experiments for the synthesis of open-chain unsymmetrical cystine-peptides (1988) (6)
Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41 (2008) (6)
Studies on Peptides. LXXXV. A New Deprotecting Procedure for p-Toluenesulfonyl and p-Methoxybenzenesulfonyl Groups from the Nim-Function of Histidine (1980) (6)
Effect of synthetic porcine neuropeptide Y (NPY) on splanchnic blood flows and Exocrine pancreatic secretion in dogs (1991) (6)
Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides (2015) (6)
A future perspective on the development of chemokine receptor CXCR4 antagonists (2008) (6)
Lewis-acid-mediated ring-exchange reaction of dihydrobenzofurans and its application to the formal total synthesis of (−)-quinocarcinamide (2012) (6)
HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains (2013) (6)
Studies on Peptides. CXVII. Solution Synthesis of the Tetratetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Growth Hormone Releasing Factor, Somatocrinin (1984) (6)
Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction. (2017) (6)
Studies on Peptides. CXXV. 3-(3-p-Methoxybenzylthiopropionyl)-thiazolidine-2-thione and Its Analogs as Reagents for the Introduction of the Mercapto Group into Peptides and Proteins (1985) (6)
The Synthesis of Alkaloids Using Transition-Metal-Catalyzed Intramolecular Amination Reactions (2013) (6)
Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas. (2018) (6)
CXCL 12 Expression by Invasive Trophoblasts Induces the Specific Migration of CD 16 Negative Human Natural Killer Cells (2003) (5)
Total synthesis of human cholecystokinin-33 (1988) (5)
Immuno-affinity purification of specific antibodies against human gastrin releasing peptide (h-GRP) by the h-GRP(1-8)-linked polydimethylacrylamide resin. (2009) (5)
Synthesis and application of an Nδ-acetyl-Nδ-hydroxyornithine analog: identification of novel metal complexes of deferriferrichrysin. (2012) (5)
Potent Anti-HIV-1 Activity of N-HR-Derived Peptides Including a Deep Pocket-Forming Region without Antagonistic Effects on T-20 (2011) (5)
Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor. (2015) (5)
Development of Mirror-Image Screening Systems for XIAP BIR3 Domain Inhibitors. (2019) (5)
Studies on peptides. CXXXVI. Solution-phase synthesis of a 37-residue peptide amide corresponding to the entire amino acid sequence of human calcitonin gene-related peptide (hCGRP). (1986) (5)
A highly stereoselective synthesis of the functionalized (E)-alkene dipeptide isostere of Trp-Val via organocyanocopper-Lewis acid mediated reaction (1997) (5)
Simple one-pot transformations of toluene-p-sulfonates of 2,3-epoxy alcohols into allylic alcohols (1996) (5)
Rapid hematopoietic progenitor mobilization by sulfated colominic acid. (2007) (5)
A convenient one-pot synthesis of cystine-containing peptides from protected peptidyl resins using the trimethylsilyl chloride–dimethyl sulfoxide–trifluoroacetic acid system (1996) (5)
Studies on peptides. CXLVIII. Application of a new deprotecting procedure with trimethylsilyl trifluoromethanesulfonate for the syntheses of two porcine spinal cord peptides, neuromedin U-8 and neuromedin U-25. (1987) (5)
N im -p-methoxyphenylsulphonylhistidine, a new derivative for peptide synthesis (1979) (5)
Studies on Peptides. CXXIX. Application of Nin-Mesitylenesulfonyl-tryptophan for the Syntheses of Neuromedin B and Neuromedin C (1985) (5)
[A study of anti-HIV compounds which interfere the virus entry via coreceptor CXCR4]. (2000) (5)
Role of sulphated tyrosine residue in influencing the biologic activity of human cholecystokinin-33. (1988) (5)
Design and synthesis of fluorescent probes for GPR54. (2014) (5)
Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design. (2013) (5)
Studies on peptides. CXXXIII. Synthesis and biological activity of galanin, a novel porcine intestinal polypeptide. (1986) (5)
Effect of synthetic human cholecystokinin-33 on exocrine pancreas. (1988) (5)
Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors. (2014) (5)
Chemokine SDF1 Mediated Bone Regeneration Using Biodegradable Poly(D,L-lactide-co-glycolide) 3D Scaffolds and Bone Marrow-Derived Mesenchymal Stem Cells: Implication for the Development of an "Off-the-Shelf" Pharmacologically Active Construct. (2020) (5)
Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing (2008) (5)
Studies on peptides. CXXX. Convenient procedure for the reduction of methionine sulfoxide. (1985) (5)
Studies on peptides. CLIV. Synthesis of a 36-residue peptide amide corresponding to the entire amino acid sequence of human pancreatic polypeptide. (1987) (5)
Synthesis of jaspine B regioisomers through palladium-catalyzed stereoselective tetrahydrofuran formation: Insight into the ligand recognition of sphingosine kinases (2018) (5)
Studies on peptides. LXX. Synthesis of two octadecapeptides corresponding to the entire amino acid sequence of camel beta-melanocyte-stimulating hormones. (1977) (4)
Structure–activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists (2015) (4)
Selective Conversion of S-Protected Cysteine Derivatives to Cystine by Various Sulphoxide-Silyl Compound / Trifluoroacetic Acid Systems (1991) (4)
Development and application of fluorescent SDF-1 derivatives. (2012) (4)
Bioactivity of synthetic human cholecystokinin (CCK)-33 in vitro and in vivo (1991) (4)
Gastrin releasing peptide-like immunoreactive substance in rat mammary glands during pregnancy. (1991) (4)
Synthesis of a 53-residue peptide with EGF activity (1984) (4)
Total synthesis of bovine pancreatic ribonuclease A. Part 5. Synthesis of the protected S-protein (positions 21–124) and the protected S-peptide (positions 1–20) (1981) (4)
Direct Disulfide Formation from 2-Quinolinylmethyl Thioethers with Iron(III) or Copper(II) Salt (1993) (4)
Studies on peptides. CXIX. Synthesis of growth hormone releasing factor (hpGRF-40-OH). (1984) (4)
Studies on Peptides. CXLIII. : Evaluation of β-Methylaspartate for Peptide Synthesis (1986) (4)
Palladium-Catalyzed sp3 C—H Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives from N-Alkyl-2-bromoanilines. (2008) (4)
Solution synthesis of a tetratetracontapeptide amide with growth hormone releasing activity. (1983) (4)
Application of S-1-adamantylcysteine to the synthesis of a 37-residue peptide amide corresponding to human calcitonin gene-related peptide (hCGRP) (1985) (4)
A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. (2015) (4)
Practical synthesis of phosphopeptides using dimethyl-protected phosphoamino acid derivatives (1995) (3)
Systematic solution-phase parallel synthesis of active vitamin D3 analogs with elongated side chains and their cell differentiation activities. (2007) (3)
Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin‐3 receptor (NK3R) ligands (2016) (3)
Application of trimethylsilyl trifluoromethanesulfonate deprotection procedure for solid phase peptide synthesis (1988) (3)
New synthetic methods of cystine-containing peptides. (1990) (3)
Monte-Carlo simulation taking account of solvent effects for a conformation analysis of peptides in solution (1994) (3)
Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants (2010) (3)
The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma (2012) (3)
generation in hu / SCID mice : implications for CXCL 12 / CXCR 4 axis in lymphoma Chemokine receptor expression in EBV-associated lymphoproliferation (2004) (3)
Total synthesis of ((±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group (Oroganic Letters (2008) 10 (5239)) (2011) (3)
Screening and characterization of cyclic pentapeptide CXCR4 antagonists/inverse agonists using a pheromone responsive reporter gene in Saccharomyces cerevisiae: Utility of G protein coupled receptor constitutively active mutants (2007) (3)
Inhibitory Mechanism of the CXCR4 Antagonist T22 against Human Immunodeficiency Virus Type 1 Infection (1999) (3)
Studies on peptides. CXX. Synthesis of growth hormone releasing factor (GRF-37-NH2) and N alpha-biotinyl-GRF-44-NH2. (1984) (3)
Effect of synthetic physalaemin on splanchnic circulation in dogs. (1989) (3)
Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus. (2009) (3)
Enzyme immunoassay of thyrotropin releasing hormone (TRH). (1992) (3)
VALIDITY OF METHOXYCARBONYL AS AN N-PROTECTING GROUP IN PEPTIDE SYNTHESIS: NEW SYNTHESIS OF MSH-RELEASE INHIBITING FACTOR (1980) (3)
Synthesis of Highly Functionalized Alkene Dipeptide Isosteres and Its Application to the Structure Activity Relationship Study on Bioactive Peptides (2008) (3)
Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3). (2018) (3)
Synthesis of potent beta-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies. (2003) (2)
Studies on peptides. CXXIV. Solution synthesis of the hentetracontapeptide amide corresponding to the entire amino acid sequence of human corticotropin releasing factor (hCRF). (1984) (2)
Development of a novel fusion inhibitor against T-20-resistant HIV-1. (2009) (2)
Gold-Catalyzed Atom-Economical Cascade Reactions of Alkynes for Ring Formation (2014) (2)
Two new disulfide bonding reactions for the synthesis of cystine peptides (1988) (2)
Efficient stereoselective synthesis of peptidomimetics containing hydroxyethylamine dipeptide isosteres utilizing the aza-Payne rearrangement and O, N-acyl transfer reactions (2002) (2)
Studies on peptides. CXLII. Synthesis of des-1-Ala-des-alpha-amino-human calcitonin gene-related peptide. (1986) (2)
Efficient Synthesis of Pyrimido[1,2-c][1,3]benzothiazin-6-imines and Related Tricyclic Heterocycles by SNAr-Type C—S, C—N, or C—O Bond Formation with Heterocumulenes. (2010) (2)
Studies on peptides. CIX. Synthesis of the octatriacontapeptide corresponding to positions 1 to 38 of human parathyroid hormone. (1982) (2)
Studies on peptides. CIV. Synthesis of ribonuclease S (1981) (2)
Fe(ii)-Complexation of tripodal hexapeptide ligands with three bidentate triazolylpyridines: induction of metal-centred chirality by peptide macrocyclization. (2017) (2)
Study of stem cell homing & self-renewal marker gene profile of ex vivo expanded human CD34+ cells manipulated with a mixture of cytokines & stromal cell-derived factor 1 (2017) (2)
Studies on Peptides. CXVI. Synthesis of the Protected Docosapeptide Corresponding to the C-Terminal Portion of Human Growth Hormone Releasing Factor (GRF, Somatocrinin) (1984) (2)
Asymmetric Intramolecular C—H/Olefin Coupling: Asymmetric Cyclization Reactions of 1,5‐Dienes Catalyzed by Rhodium Complexes. (1997) (2)
One-pot transformation of p-toluenesulfonates of 2,3-epoxy alcohols into allyic alcohols (1997) (2)
Synthesis and functional analysis of deferriferrichrysin derivatives: application to colorimetric pH indicators. (2013) (2)
Pan-Histone Deacetylase (HDAC) Inhibitor LBH589 Depletes CXCR4 Levels and Signaling, Exerting Synergistic Anti-Leukemia Activity in Combination with CXCR4 Antagonists. (2007) (2)
Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method (2015) (2)
Inhibition of HIV-1 replication and syncytium formation by synthetic CD 4 peptides Brief Report (2)
Studies on peptides LXV. Conventional synthesis of a new hypothalamic peptide, bovine neurotensin. (1976) (2)
Synthesis and in vitro evaluation of a bimodal CXCR4 antagonistic peptide (2013) (2)
Facile Synthesis of 1,2,3,4-Tetrahydro-β-carbolines by One-Pot Domino Three-Component Indole Formation and Nucleophilic Cyclization. (2009) (2)
Inhibition of HIV-1 replication and syncytium formation by synthetic CD4 peptides (2005) (2)
Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy. (2009) (2)
One‐Pot Synthesis of Carbazoles by Palladium‐Catalyzed N‐Arylation and Oxidative Coupling. (2008) (2)
SmI2‐Mediated Reduction of γ,γ‐Difluoro‐α,β‐enoates with Application to the Synthesis of Functionalized (Z)‐Fluoroalkene‐Type Dipeptide Isosteres. (2004) (2)
Studies on Peptides. CXII. Alternative Synthesis of Heptacosapeptide, a New Gastrointestinal Polypeptide (1983) (2)
Studies on peptides. LI. Application of the solid phase synthesis for the preparation of pro-analogues of LH and FSH releasing hormone. (1975) (2)
Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety. (2002) (2)
Direct Assessment of CXCR4 Mutant Conformations Reveals Complex Link between Receptor Structure and Gαi Activation* (2007) (2)
Preparation of peptide-carrying microspheres with bioactivity on platelets. (1993) (2)
Studies on Peptides. CXIV. Synthesis of Hylambates-Kassinin, a Frog Skin Tachykinin Peptide (1983) (2)
Studies on peptides. CXVIII. Synthesis of a hybrid growth hormone releasing factor (GRF)-PHI heptacosapeptide amide. (1984) (2)
Potassium Carbonate Promoted Stereospecific 5‐endo‐trig Cyclization of Unactivated Allenes in the Absence of Any Transition Metals. (2006) (2)
Chapter 20 Expression of CXCR4, a G‐Protein–Coupled Receptor for CXCL12 in Yeast (2009) (2)
Dual Gold Catalysis: A Novel Synthesis of Bicyclic and Tricyclic Pyrroles from N‐Propargyl Ynamides. (2015) (1)
Synthesis of (+)-Lysergic Acid, (+)-Lysergol, and(+)-Isolysergol (2011) (1)
SYNTHESIS OF A HENTETRACONTAPEPTIDE AMIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN CORTICOTROPIN RELEASING FACTOR (hCRF) (1984) (1)
Identification of Binding Proteins of an Anti-HIV Peptide, T22 (1995) (1)
Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents. (2009) (1)
Simple One-Pot Transformations of Toluene-p-sulfonates of 2,3-Epoxy Alcohols into Allylic Alcohols. (1996) (1)
A Highly Regio‐ and Stereoselective Formation of Bicyclo[4.2.0]oct‐5‐ene Derivatives Through Thermal Intramolecular [2 + 2] Cycloaddition of Allenes. (2007) (1)
Effects of membrane charge and transmembrane potential on the interactions of β-sheet peptides (tachyplesin I, defensin, gramicidin S) with lipid bilayers (1993) (1)
Selective Synthesis of cis-2-Vinyl-3-alkylaziridines and 3-Pyrrolines from Common Intermediates (Z)-4-N-Arylsulfonylaminoalk-2-en-1-ols. (1999) (1)
ROLE OF METHIONINE IN THE FACILITATED CLEAVAGE OF AROMATIC ETHERS BY METHANESULFONIC ACID (1977) (1)
STUDIES ON PEPTIDES. CXXV. 3-(3-P-METHOXYBENZYLTHIOPROPIONYL)THIAZOLIDINE-2-THIONE AND ITS ANALOGS AS REAGENTS FOR THE INTRODUCTION OF THE MERCAPTO GROUP INTO PEPTIDES AND PROTEINS (1985) (1)
Stereoselective Synthesis of Nonracemic 1,3-Amino Alcohols from Chiral 2-Vinylaziridines by InI—Pd(0)-Promoted Metalation. (2001) (1)
Synthesis of β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere and their Structure-activity Relationship Studies (2005) (1)
Unprecedented Rearrangement Reaction of 2-Aziridinemethanols with “ Lower Order” Lithium Methylcyanocuprate. (1994) (1)
Syn‐SN2′ Pathway in the Reaction of Certain γ‐(Mesyloxy) α, β‐Enoates with RCu(CN)MgX×BF3 Reagents. Importance of MgX and Bulky R Group upon the Diastereoselectivity. (1993) (1)
Immuno-affinity purification of specific antibodies against vasoactive intestinal polypeptide (VIP) on VIP (1-10)-linked polydimethylacrylamide resin. (1989) (1)
Isolation, Structure Elucidation, and Total Synthesis of Tryptopeptins A and B, New TGF‐β Signaling Modulators from Streptomyces sp. (2015) (1)
Formal [4 + 2] Reaction Between 1,3‐Diynes and Pyrroles: Gold(I)‐Catalyzed Indole Synthesis by Double Hydroarylation. (2015) (1)
Preparation and Evaluation of Polymer Microspheres with Cell Adhesion Activity (1993) (1)
Kiss1 cDNA Cloning and Induction of Ovulation by Peripheral Administration of Various Kisspeptins in the Musk Shrew (Suncus murinus), a Reflex Ovulator. (2010) (1)
Direct Synthesis of Fused Indoles by Gold‐Catalyzed Cascade Cyclization of Diynes. (2011) (1)
Design and Synthesis of Highly Active Anti-HIV Peptide Based on Gp41-C34 Peptide (2002) (1)
Efficient Synthesis of Cyclic RGD Pseudopeptide with (E)-Alkene Dipeptide Isostere and Its Biological Activity (2001) (1)
Microenzyme immunoassay for the measurement of brain natriuretic peptide (BNP)-like immunoreactivity in porcine plasma. (1990) (1)
Title Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide (2016) (1)
Synthesis of (Z)‐Fluoroalkene Dipeptide Isosteres Utilizing Organocopper‐Mediated Reduction of γ,γ‐Difluoro‐α,β‐enoates. (2001) (1)
SN2′ Ring Opening of Aziridines Bearing an α,β-Unsaturated Ester Group with Organocopper Reagents. A New Stereoselective Synthetic Route to (E)-Alkene Dipeptide Isosteres. (1995) (1)
CXCR4 Antagonists Identified as Anti-Cancer-Metastatic Agents (2004) (1)
Gold‐Catalyzed Cascade Cyclization of (Azido)ynamides: An Efficient Strategy for the Construction of Indoloquinolines. (2014) (1)
Development of Copper‐Mediated Allylation of γ‐Activated‐α,β‐Unsaturated Lactam Toward Peptide Mimetic Synthesis. (2007) (1)
Studies on peptides. CXXXVII. Conventional solution synthesis of porcine hypothalamic growth hormone releasing factor (pGRF). (1986) (1)
Ring‐Construction/Stereoselective Functionalization Cascade: Total Synthesis of Pachastrissamine (Jaspine B) Through Palladium‐Catalyzed Bis‐cyclization of Propargyl Chlorides and Carbonates. (2010) (1)
High-throughput turbidimetric screening for heparin-neutralizing agents and low-molecular-weight heparin mimetics. (2012) (1)
Synthesis of the Src SH2 domain and its application in bioassays for mirror-image screening (2017) (1)
Therapeutic Discovery GPR 54 Is a Target for Suppression of Metastasis in Endometrial Cancer (2011) (1)
Sterically Congested Chiral Activated Aziridines: Synthesis of Both 2,3-cis- and 2,3-trans-2-Alkenyl-3-alkylaziridines from Common Intermediates. (1999) (1)
A Novel One‐Pot Reaction Involving Organocopper‐Mediated Reduction/Transmetalation/Asymmetric Alkylation, Leading to the Diastereoselective Synthesis of Functionalized (Z)‐Fluoroalkene Dipeptide Isosteres. (2007) (1)
Synthesis of Optically Pure 2‐Aziridinemethanols: Versatile Synthetic Building Blocks. (1995) (1)
Synthesis of Highly Functionalized Alkene Dipeptide Isosteres and Its Application to the Structure—Activity Relationship Study on Bioactive Peptides (2009) (1)
Reactions of N‐Arylsulfonyl‐2,3‐cis‐ and N‐Arylsulfonyl‐2,3‐trans‐3‐alkyl‐2‐vinylaziridines with Organocopper Reagents: Importance of 2,3‐cis‐Stereochemistry in Controlling Regio‐ and Stereoselectivity. (1999) (1)
Inhibitors of the Chemokine Receptor CXCR4: Chemotherapy of AIDS, Metastatic Cancer, Leukemia and Rheumatoid Arthritis (2007) (1)
Metabolism of cholecystokinin-33 in vivo: effect of L-364,718, a CCK receptor antagonist. (1994) (1)
New Procedure for the Synthesis of Cystine-Peptides by Oxidation of S-Substituted Cysteine-Peptides with Thallium(III) Trifluoroacetate. (1987) (1)
Gold‐Catalyzed Hydroarylation of Allenes: A Highly Regioselective Carbon—Carbon Bond Formation Producing Six‐Membered Rings. (2008) (1)
Synthesis of Fused and Linked Bicyclic Nitrogen Heterocycles by Palladium‐Catalyzed Domino Cyclization of Propargyl Bromides. (2010) (1)
(E)-Stereoselective Synthesis of Vinylglycines from (R)-Serine via Organocopper-BF3 and Related Reagents. (1995) (0)
Stereoselective Synthesis of a Set of Two Functionalized (E)‐Alkene Dipeptide Isosteres of L‐Amino Acid‐L‐Glu and L‐Amino Acid‐D‐Glu. (2002) (0)
Stereoselective Synthesis of CF_2 or CHF-Substituted Phosphoamino Acids and Their Incorporation into Peptides (2001) (0)
New Synthetic Methods of Cystine-Containing Peptides (2010) (0)
Efficient Stereoselective Synthesis of Peptidomimetics Containing Hydroxyethylamine Dipeptide Isosteres Utilizing the Aza‐Payne Rearrangement and O,N‐Acyl Transfer Reactions. (2002) (0)
New Strategy for The Synthesis of Aspartyl Protease Inhibitor Based on "Aza-Payne Rearrangement" (2000) (0)
Development of Potent β-Secretase Inhibitors Containing a Hydroxyethylamine Dipeptide Isostere (2004) (0)
Synthetic Studies on 7TM-GPCR (I) : Lipid Bilayer Assisted Membrane Peptide Ligation (2004) (0)
Practical Phosphoeptides Synthesis Using Dimenthylphosphono Amino Acids (No.2) (1995) (0)
Synthesis of CXCR4 Antagonists, T140 Derivatives with Improved Biostability, and Their SAR Study (2003) (0)
Contents list. (2016) (0)
Direct Synthesis of Quinazolines Through Copper‐Catalyzed Reaction of Aniline‐Derived Benzamidines. (2010) (0)
Gold‐Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl‐Annulated[a]carbazoles from Aniline‐Substituted Diethynylarenes. (2010) (0)
Stereoselective Synthesis of 2‐Alkenylaziridines and 2‐Alkenylazetidines by Palladium‐Catalyzed Intramolecular Amination of α‐ and β‐Amino Allenes. (2001) (0)
Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated anti-S(N)2' reactions. (2002) (0)
Studies on peptides. CXXXVIII. Conventional solution synthesis of bovine hypothalamic growth hormone releasing factor (bGRF). (1986) (0)
Direct Construction of Bicyclic Heterocycles by Palladium‐Catalyzed Domino Cyclization of Propargyl Bromides. (2008) (0)
Palladium-Catalyzed Biscyclization of Allenic Bromoalkenes Through a Zipper-Mode Cascade. (2008) (0)
Synthesis of Fluoroalkene Dipeptide Isosteres Utilizing Organocopper or SmI_2 Reagents (2002) (0)
STUDIES ON PEPTIDES. LXX. SYNTHESIS OF TWO OCTADECAPEPTIDES CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF CAMEL β-MELANOCYTE-STIMULATING HORMONES (1977) (0)
Double C—H Functionalization in Sequential Order: Direct Synthesis of Polycyclic Compounds by a Palladium‐Catalyzed C—H Alkenylation—Arylation Cascade. (2012) (0)
Acid-catalyzed Ring-opening Reactions of β-Aziridinyl-α, β-enoates and Their Application (2003) (0)
Synthesis of a CXCR4 Antagonist (2006) (0)
An Aza-Payne Rearrangement-Epoxide Ring Opening Reaction of 2- Aziridinemethanols in a One-Pot Manner: A Regio- and Stereoselective Synthetic Route to Diastereomerically Pure N-Protected 1,2-Amino Alcohols. (1997) (0)
One-Pot Synthesis of Carbazoles via Subse-quent N-Arylation and Oxidative Coupling (2008) (0)
Structure-Activity Relationship Study on hOT7T175 Agonist with RW-Amide (2006) (0)
Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetrapeptide-scaffolds (2005) (0)
Stereoselective Synthesis of Tyr-Orn Type Alkene Dipeptide Isosteres and Their Application to Bioactive Peptides (2011) (0)
Longitudinal imaging of CXCR 4 1 Non-invasive longitudinal imaging of tumor progression using an 111 Indium labeled CXCR 4 peptide antagonist (2011) (0)
Studies on peptides. CLXIII. Synthesis of guinea pig vasoactive intestinal polypeptide (gVIP). (1988) (0)
Specific Fluorescence Labeling of Membrane Receptors in Living Cells using Coiled-coil Tag (2008) (0)
A Convenient One-Pot Synthesis of Cystine-Containing Peptides from Protected Peptidyl Resins Using the Trimethylsilyl Chloride-Dimethyl Sulfoxide-Trifluoroacetic Acid System. (1997) (0)
STUDIES ON PEPTIDES. CXIII. SYNTHESIS OF THE HEPTACOSAPEPTIDE AMIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF CHICKEN SECRETIN (1984) (0)
SN2′ Selective Alkylation of Allylic Chlorides and Mesylates with RZnX Reagents Generated from Grignard Reagents, Zinc Chloride, Lithium Chloride, and Cu(II) Salts. (1993) (0)
Synthesis of Nonhydrolyzable Phosphothreonine Derivatives and Their Practical Application to Peptide Synthesis (1998) (0)
P-423 Structure-Activity Relationship Studies on Cyclic Peptide-Based CXCR4 Antagonists (2006) (0)
A Modified Benzhydrylamine as a Handle Reagent for the Solid Phase Synthesis of Peptide Amides Based on the Fluorenylmethoxycarbonyl Method. (1988) (0)
Synthesis of selenocystine-containing peptides (1993) (0)
STUDIES ON PEPTIDES. CXIX. SYNTHESIS OF GROWTH HORMONE RELEASING FACTOR (HPGRF-40-OH) (1984) (0)
Synthesis and Application of Novel Fluorescence-Labeled CXCR4 Antagonists (2008) (0)
Diastereoselective Synthesis of Trifluoromethylalkene Dipeptide Isosteres Based on Nucleophilic Trifluoromethylation (2009) (0)
TMSX (X=OTf, Br, I) as Deprotecting Reagents for Peptide Synthesis (1990) (0)
Endeavors for Highly Stereoselective Synthesis of Functionalized Fluoroalkene Dipeptide Isosteres (2006) (0)
Enhanced plasmid DNA transfer into tumor cells by nanoparticle composed of cholesteryl triamine and diamine. (2013) (0)
Synthesis of Fused Carbazoles by Gold‐Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N‐Propargyl Group. (2016) (0)
HIV-cell Fusion Inhibitors Targeted to the HIV Second Receptor : T22 and Its Downsized Analogs with High Activity (1998) (0)
A Highly Stereoselective Synthesis of the Functionalized (E)‐Alkene Dipeptide Isostere of Trp—Val via Organocyanocopper—Lewis Acid Mediated Reaction. (1996) (0)
Title Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C (2019) (0)
cell niches requires CXCL12-CXCR4 chemokine signaling Development of plasmacytoid dendritic cells in bone marrow stromal (2011) (0)
Effect of pan-histone deacetylase inhibitor panobinostat (LBH589) on CXCR4 levels and signaling and on anti-leukemia activity in combination with CXCR4 antagonists (2008) (0)
Gold‐Catalyzed Atom‐Economical Cascade Reactions of Alkynes for Ring Formation (2015) (0)
SmI2-mediated reduction of gamma,gamma-difluoro-alpha,beta-enoates with application to the synthesis of functionalized (Z)-fluoroalkene-type dipeptide isosteres. (2004) (0)
Synthesis of (Z)-Alkene cis-Xaa-Pro Type Dipeptide Isosteres Using Organocopper-Mediated Anti-S_N2' Reactions (2007) (0)
Development in Vivo CXCR4 in Fetal and Adult T Cell Growth Stimulating Factor and Its Receptor 12/Stromal Cell-Derived Factor-1/Pre-B Cell A Role of CXC Chemokine Ligand (2003) (0)
Structure-Activity Relationship Study of CXCR4 Antagonists on the Cyclic Pentapeptide Scaffold : Identification of New Pharmacophore Moieties (2009) (0)
Design, Synthesis and Activity of Shortened Analogs of an Anti-HIV Peptide, T22 (1995) (0)
The CXCR4 antagonist T140 has a sustained inverse agonist effect. (2003) (0)
A THERMODYNAMIC PREFERENCE OF CHIRAL CIS-GAMMA -DELTA -EPIMINO-(E)-ALPHA ,BETA -UNSATURATED ESTERS OVER OTHER STEREOISOMERS : SYNTHETICALLY USEFUL PD( 0)-CATALYZED EQUILIBRATED REACTIONS OF AZIRIDINES BEARING AN ALPHA ,BETA -U NSATURATED ESTER GROUP (1996) (0)
virus-cell fusion. Lys-7)polyphemusin II): a possible inhibitor of a novel synthetic peptide, T22 ((Tyr-5,12, Anti-human immunodeficiency virus activity of (2014) (0)
Diastereoselective Synthesis of (Z)-Fluoroalkene Dipeptide Isostere and the Application to a HIV Membrane Fusion Inhibitor (2009) (0)
Properties of Intracellular Fragment Peptides of Mouse Prostaglandin E_2 Receptor EP3 Isoform (2008) (0)
CXCR4 Blockade as a New Targeted Therapy for Acute Myeloide Leukemia Characterised by High Cell Surface Density of CXCR4. (2009) (0)
Stereoselective Synthesis of Chiral Amino Allenes by Organocopper-Mediated anti-SN2′-Substitution Reaction of Chiral Ethynylaziridines. (2001) (0)
Application of Samarium Diiodide (SmI2)-Induced Reduction of γ-Acetoxy-α,β-enoates with α-Specific Kinetic Electrophilic Trapping for the Synthesis of Amino Acid Derivatives. (2003) (0)
Expression of functional cxcr4 in saccharomyces cells: a model system for analysis of receptor interactions (2000) (0)
Diversity-Oriented Synthesis of Pyrazolo[4,3-b]indoles by Gold-Catalyzed Three-Component Annulation: Application to the Development of a New Class of CK2 Inhibitors. (2013) (0)
Synthesis of Peptide Thioester Based on N-S Acyl Transfer Utilizing Cysteine-derived Acyloxazolidinone with Practical Application to Peptide Synthesis (2006) (0)
Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors (2016) (0)
Direct Disulfide Formation from 2‐Quinolinylmethyl Thioethers with Iron(III) or Copper(II) Salt. (1994) (0)
Human immunodeficiency virus infection and cell membrane (1994) (0)
P-485 Development of Synthetic Methodology toward (Z)-Fluoroalkene Dipeptide Isosteres Based on the Concept of Organometalic-Mediated C-F Bond Cleavage (2006) (0)
Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. (2009) (0)
Palladium-Catalyzed Direct One-Pot Synthesis of Carbazoles (2009) (0)
Ny Science daerav framstaelld the polypeptide of HIV Medicine. (1992) (0)
Versatile Use of Acid-Catalyzed Ring-Opening of β-Aziridinyl-α,β-enoates to Stereoselective Synthesis of Peptidomimetics. (2008) (0)
Development of the Chemokine Receptor CXCR4 Antagonists as Multi-Pharmaceutical Agents Involving a New Class of Low Molecular Weight Antagonists (2007) (0)
Heptad repeat-derived peptides block the protease-mediated direct entry from cell surface of SARS coronavirus but not entry via endosomal pathway (2017) (0)
Crystal structure of the complex between gp41 fragments N36 and C34 mutant N126K/E137Q (2010) (0)
Synthesis of Pyrroloindoles and Dipyrrolo-pyridines by aHydroamination Route (2009) (0)
X-ray Crystallographic Study of the HIV-1 Fusion Inhibitor against the Drug-Resistant N43D Variant (2009) (0)
A novel RGD peptide inhibited tumor growth in vivo via anti-anglogenic mechanism (2001) (0)
Functional Characterization of Kisspeptin Receptor Ligands : Activation of Neuropeptide FF Receptors (2011) (0)
Helix Inducible Motifs Affect Helicity and Bioactivity of Anti-HIV Peptides (2008) (0)
Activation of Rho and ROCK by GPR54 and KiSS1 Metastasis Suppressor Gene Product Induces Changes of Cell Morphology and Contributes to Apoptosis (2009) (0)
Crystal structure of the complex between GP41 fragment N36 and fusion inhibitor C34/S138A (2009) (0)
Facile Synthesis of Fluoroalkenes by Palladium‐Catalyzed Reductive Defluorination of Allylic gem‐Difluorides. (2007) (0)
Diastereoselective Synthesis of Highly Functionalized Fluoroalkene Dipeptide Isosteres and Its Application to Fmoc-Based Solid-Phase Synthesis of a Cyclic Pentapeptide Mimetic. (2008) (0)
migration of CD16 negative human natural killer cells CXCL12 expression by invasive trophoblasts induces the specific (2013) (0)
A 2,3‐cis‐Selective Synthesis of Aziridines Bearing a Vinyl Group from Allyl Methyl Carbonates and Allyl Mesylates. (1999) (0)
Application of samarium diiodide (SmI2)-induced reduction of gamma-acetoxy-alpha,beta-enoates with alpha-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives. (2003) (0)
Palladium‐Catalyzed Construction of Polycyclic Heterocycles by an Alkyne Insertion and Direct Arylation Cascade. (2011) (0)
Stereoselective synthesis of 2-alkenylaziridines and 2-alkenylazetidines by palladium-catalyzed intramolecular amination of alpha- and beta-amino allenes. (2001) (0)
Heck-Type Cyclization of Oxime Ethers: Stereoselective Carbon—Carbon Bond Formation with Aryl Halides to Produce Heterocyclic Oximes. (2007) (0)
New polypeptides and anti-HIV drugs made thereof (1991) (0)
Palladium-Catalyzed Regio- and Stereoselective Synthesis of N-Protected 2,4-Dialkylated Azacyclobutanes from Amino Allenes. (2000) (0)
Convenient Syntheses of Chiral 3-Substituted 2-Ethynylaziridines. (2000) (0)
An aromatic amino acid in the i2 loop is essential for association of Gs protein in the prostaglandin E receptors EP2 and EP3 (2005) (0)
Orientation and aggregation of magainin in lipid bilayers (1993) (0)
Stereo-controlled Synthesis of [L-Arg, L/D-3-(2-Naphthyl)alanine]-type (E)-Alkene Dipeptide Isosteres and its Application to the Preparation and Biological Evaluation of Peptidomimetic Analogs of the CXCR4 Antagonist FC131 (2006) (0)
PB24 TWO NEW DISULFIDE BOND FORMING REACTIONS AND THEIR APPLICATION TO THE SYNTHESES OF HUMAN AND CHICKEN CALCITONIN GENE RELATED PEPTIDES (1988) (0)
Synthesis of Novel Anti-HIV Peptides Based on a CXCR4 Antagonist, T140, and Their SAR Study (2002) (0)
STUDIES ON PEPTIDES. LXV. CONVENTIONAL SYNTHESIS OF A NEW HYPOTHALAMIC PEPTIDE, BOVINE NEUROTENSIN (1977) (0)
[Peptide-lead drug discovery]. (2007) (0)
Novel Synthesis of Chiral Terminal Allenes via Palladium(0)‐Catalyzed Reduction of Mesylates of 2‐Bromoalk‐2‐en‐1‐ols Bearing a Protected Amino Group, Using Diethylzinc. (2000) (0)
Synthesis of Alkene Type Dipeptide Isosteres and Their Use to Probe the Structural Requirements of Peptide Transporter (PEPT1) (2006) (0)
Nin-Mesitylene-2-sulfonylyryptophan, a New Tryptophan Derivative, and Its Application for Peptide Synthesis (1984) (0)
Anti-Human Immunodeficiency VirusActivity ofaNovelSynthetic Peptide, T22((Tyr-5,12, Lys-7)Polyphemusin (1992) (0)
Translocation of Basic Peptides through Human Cell Membranes (2002) (0)
Bromoallenes as Allyl Dication Equivalents in the Presence or Absence of Palladium(0): Direct Construction of Bicyclic Sulfamides Containing Five‐ to Eight‐Membered Rings by Tandem Cyclization of Bromoallenes. (2007) (0)
Stereoselective Synthesis of Peptidomimetics Based on Acid-catalyzed Ring-opening of β-Aziridinyl-α,β-enoates (2009) (0)
Development of Novel GPR54 Agonists with Resistance to Degradation by MMP (2009) (0)
Lewis Acid Mediated Ring Exchange Reaction of Dihydrobenzofurans and Its Application to the Formal Total Synthesis of (-)-Quinocarcinamide (VIII). (2013) (0)
Regio- and Stereoselective Synthesis of (E)-Alkene trans-Xaa-Pro Dipeptide Mimetics Utilizing Organocopper-Mediated anti-SN2′ Reactions. (2003) (0)
STRUCTURE-ACTIVITY RELATIONSHIPS OF TACHYPLESIN ANALOGS AS ANTI-HIV AGENT (1992) (0)
Title A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo (2018) (0)
Synthesis of Indolines via C-H Activation of N-tert-Butyl-2-bromoanilines (2008) (0)
Front cover. (2016) (0)
Synthetic Studies on Coibamide A (2011) (0)
Utility of Plasma Bioactive Peptides Levels as Biomarkers (2009) (0)
New Access to α‐Substituted (Z)‐Fluoroalkene Dipeptide Isosteres Utilizing Organocopper Reagents under “Reduction—Oxidative Alkylation (R—OA)” Conditions. (2001) (0)
STUDIES ON PEPTIDES PART 51, APPLICATION OF THE SOLID PHASE SYNTHESIS FOR THE PREPARATION OF PRO‐ANALOGUES OF LH AND FSH RELEASING HORMONE (1975) (0)
Unequivocal Synthesis of (Z)-Alkene or (E)-Fluoroalkene Dipeptide Isosteres via DKP Mimetics to Probe Structural Requirements of Peptide Transporter (2006) (0)
Zipper‐Mode Double C—H Activation: Palladium‐Catalyzed Direct Construction of Highly Fused Heterocyclic Systems. (2008) (0)
Synthetic Studies of Tokaramide A and Miraziridine A Isolated from Marine Sponge Theonella aff. mirabilis (2006) (0)
Development of Specific CXCR4 Inhibitors Based on an Anti-HIV Peptide, T140, and Their Structure-Activity Relationships Study (2001) (0)
Diastereoselective Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-Type Dipeptide Isosteres by Organocopper-Mediated anti-SN2′ Reaction. (2002) (0)
Development of novel neurokinin-3 receptor agonists that potently stimulate the GnRH pulse generator (2014) (0)
STUDIES ON PEPTIDES PART 50, ACIDOLYSIS OF PROTECTING GROUPS IN PEPTIDE CHEMISTRY BY FLUOROSULPHONIC ACID AND METHANESULPHONIC ACID (1975) (0)
Gold‐Catalyzed Cascade Cyclization of 2‐Alkynyl‐N‐Propargylanilines by Rearrangement of a Propargyl Group. (2015) (0)
The affinity purification procedure for peptide synthesized by the solid-phase technique (1993) (0)
4-(Dimethylamino)phenacyl Group : New Photoremovable Protecting Group for Amines and Carboxylic Acids (2005) (0)
Facile Synthesis of 3-(Aminomethyl)isoquinolines by Copper-Catalyzed Domino Four-Component Coupling and Cyclization. (2008) (0)
Synthesis of (E)-Alkene trans-Xaa-Pro Mimetics Using Organocopper Reagents (2003) (0)
Convenient Synthesis of Spiroindole Derivatives via Palladium-Catalyzed Cyclization of Propargyl Chlorides. (2015) (0)
Asymmetric Synthesis of β2,3‐Amino Acids by InI—Pd(0)‐Promoted Metalation and Addition of Chiral 2‐Vinylaziridines. (2002) (0)
Construction of Nitrogen Heterocycles Bearing an Aminomethyl Group by Copper‐Catalyzed Domino Three‐Component Coupling—Cyclization. (2010) (0)
Development of New Photoremovable Amino Protecting Group and its Application toward Chemical Synthesis of 7TM-GPCR (2006) (0)
Synthesis of Chiral Amino Allenes via an Organocyanocuprate‐Mediated Ring‐Opening Reaction of Enantiopure Ethynylaziridines. (1999) (0)
Development of New Methodology for the Synthesis of Functionalized α‐Fluorophosphonates and Its Practical Application to the Preparation of Phosphopeptide Mimetics. (2000) (0)
Bioorganic Synthesis of End-capped HIV-1 Fusion Inhibitor SC35EK (2009) (0)
Copper-Catalyzed Synthesis of Tetrahydro-β-carbolines (2009) (0)
Transition Metal-Catalyzed Intramolecular Cyclization of 1,5- and 1,6-Dienes via Direct Cleavage and Addition of the Carbon—Hydrogen Bond. (1998) (0)
Synthesis of Fused Tetracyclic Spiroindoles via Palladium-Catalyzed Cascade Cyclization. (2014) (0)
STUDIES ON PEPTIDES. LXXIII. EXAMINATION OF THE METHANESULFONIC ACID PROCEDURE FOR THE SYNTHESIS OF PEPTIDES CONTAINING METHIONINE (1978) (0)
The Effect of Kisspeptin Receptor Agonist (FTM080) on Luteinizing Hormone in Sheep (2011) (0)
Total Synthesis of Bovine Pancreatic Ribonuclease A (1980) (0)
A Novel KSP Inhibitor, KPYB10602, Induces Mitotic Arrest and Cell Death in Breast Cancer Cells (2016) (0)
Development of Fusion-inhibiting Anti-HIV-1 Peptides Based on the Structure of Molecular Complex Involved in HIV-1-cell Fusion (2003) (0)
Synthesis of ψ[(E)-CMe=CMe]- and ψ[(E)-CMe=CH]-type Alkene Dipeptide Isosteres from a Chiral Amino Acid (2002) (0)
derivatives and their use metastin (2004) (0)
First Palladium‐Catalyzed Aziridination Reaction of Amino Allenes. (1999) (0)
A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for imaging tumors (2011) (0)
Fluoroalkene Skeleton as a Peptide Bond Mimetic : Its Scope and Limitations (2008) (0)
A One-Pot Aza-Payne Rearrangement-Epoxide Ring Opening Reaction of 2- Aziridinemethanols: A Regio- and Stereoselective Synthetic Route to Diastereomerically Pure 1,2-Amino Alcohols. (1995) (0)
Sulfated Colominic Acid Enhances CXCR4 Function and Promotes Hematopoietic Stem /Progenitor Egress from Bone Marrow. (2005) (0)
Regio‐ and Stereoselective Ring‐Opening of Chiral 1,3‐Oxazolidin‐2‐one Derivatives by Organocopper Reagents Provides Novel Access to Di‐, Tri‐ and Tetra‐Substituted Alkene Dipeptide Isosteres. (2003) (0)
STUDIES ON PEPTIDES PART 48, APPLICATION OF THE TRIFLUOROMETHANESULPHONIC ACID PROCEDURE TO THE SYNTHESIS OF TUFTSIN (1975) (0)
Synthesis of ()-Lysergic Acid (2009) (0)
Synthesis of a CC Chemokine, vMIP-II, Encoded by Kaposi's Sarcoma-Associated Herpesvirus and Its Biological Activity (1998) (0)
Tl (OCOCF3) 3 as a Disulfide Bond-forming Reagent (1990) (0)
Dual Gold Catalysis: Synthesis of Polycyclic Compounds via C—H Insertion of Gold Vinylidenes. (2015) (0)
Interactions of C terminal truncated magainin 2 with lipid membranes (1993) (0)
MP-20.01: Fluorescent Imaging of Bladder Cancer Using T140 Analogue, A CXCR4 Antagonistic Peptide (2009) (0)
Structure-Activity Relationship Study of Tachykinin Peptides for the Development of Novel NK3 Receptor Agonists (2013) (0)
Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type Dipeptide Isosteres and their Application to a Cyclic RGD Peptide (2002) (0)
Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to κ-Opioid Receptor. (2016) (0)
Synthesis of Fluorine‐Containing Bioisosteres Corresponding to Phosphoamino Acids and Dipeptide Units (2004) (0)
400. Peptide-Mediated Gene Transfer of Lipid/ DNA-Based Complexes to Cells Expressing CXC- Receptor 4 (2006) (0)
STUDIES ON PEPTIDES. CXX. SYNTHESIS OF GROWTH HORMONE RELEASING FACTOR (GRF-37-NH2) AND Nα-BIOTINYL-GRF-44-NH2 (1984) (0)
Highly stereoselective synthesis of (E)-alkene dipeptide isosteres via organocopper mediated 1,3-chirality transfer reaction and its application to the synthesis of a potent bombesin antagonist with no agonistic activity (1995) (0)
Stereoselective Synthesis of Diketopiperazine Mimetics as Promising Scaffolds for Drug Discovery Utilizing Organocopper-Mediated anti-S_N2' Reaction (2005) (0)
Synthesis and Biological Evaluation of Peptidomimetic Analogs of the CXCR4 Antagonist FC131 (2006) (0)
A Convenient Synthesis of Activated Enantiomerically Pure 2-Ethynylaziridines. (1999) (0)
Synthesis and Investigation of Ferrichrysin Derivatives (2015) (0)
Stereoselective Synthesis of Peptidomimetics with Hydroxyethylamine Dipeptide Isosteres Utilizing Aza-Payne Rearrangement and O, N-Acyl Transfer Reactions (2003) (0)
REGIOSELECTIVE CLEAVAGE OF AROMATIC METHYL ETHERS BY METHANESULFONIC ACID IN THE PRESENCE OF METHIONINE (1978) (0)
Identification of a Polyphemusin Analog(T22)-Zn(II) Complex by Mass Spectrometric Analysis and Its Anti-HIV Activity (1996) (0)
Amino Acid Based Synthesis of Trifluoromethylalkene Dipeptide Isosteres by Alcohol-Assisted Nucleophilic Trifluoromethylation and Organozinc—Copper-Mediated SN2′ Alkylation. (2009) (0)
Regio- and Stereoselectivity in Reactions of 2,3-cis- and trans-3-Alkyl-2-vinylaziridines with Organocopper Reagents: Importance of 2,3-cis-Stereochemistry in Controlling Selectivity. (1998) (0)
Inside Back Cover: Wurster’s Blue-type Cation Radicals Framed in a 5,10-Dihydrobenzo[a]indolo[2,3-c]carbazole (BIC) Skeleton: Dual Electrochromism with Drastic Changes in UV/Vis/NIR and Fluorescence (Chem. Asian J. 7/2014) (2014) (0)
Synthesis and Investigation of Novel Metal Complexes of Deferriferrichrysin (2013) (0)
Efficient Synthesis of Aminomethylated Azaindoles and Corresponding Pyrrole‐Fused Derivatives by Copper‐Catalyzed Domino Multicomponent Coupling and Cyclization. (2012) (0)
Synthesis of Fluoroalkene Dipeptide Isosteres Utilizing Organometallic Reagents (2001) (0)
Identification of Novel HIV-1 Fusion Inhibitors by Template-Assisted Peptide Aldehyde Ligation (2009) (0)
Establishment and Clinical Application of an Enzyme Immunoassay for Metastin to Determination of the Human Plasma Levels (2007) (0)
Remarkable Difference in Reactivity of Ordinary Vinylcopper Reagents and Vinylzinc Halide Containing a Copper Salt Towards γ‐Mesyloxy‐ α,β‐enoates. Synthesis of Homochiral 1,4‐Dienes. (1994) (0)
Stereodivergent Synthesis of Chiral 2‐Alkenylaziridines: Palladium(0)‐Catalyzed 2,3‐cis‐Selective Aziridination and Base‐Mediated 2,3‐trans‐Selective Aziridination. (2004) (0)
Structure Activity Relationship Study of the Helix-inducible Motifs in HIV Fusion Inhibitors (2009) (0)
Palladium-Catalyzed Reductive Ring Opening with Formic Acid of Aziridines Bearing an α,β-Unsaturated Ester Group. (1998) (0)
A New Strategy for Molecular-size Reduction of Bioactive Peptide, Using Two Orthogonal Libraries of Cyclic peptides (2004) (0)
Gold-Catalyzed Hydroamination-Hydroarylation Routeto Fused Indoles (2011) (0)
Crystal structure of potent anti-HIV peptide, N36 complexed with C34KQ derived from N36-resistant strain (2001) (0)
P-467 Structure-activity relationship study on GPR54 agonists (2006) (0)
Biological Activity of a Cyclic Peptide from Laminin α1 Chain Loop Region (2004) (0)
New Leads of Low Molecular Weight CXCR4 Antagonists Based on Enhancement of the T140-based Pharmacophores (2004) (0)
Cu(II)-Mediated Oxidative Intermolecular ortho C—H Functionalization Using Tetrahydropyrimidine as the Directing Group. (2009) (0)
Synergism of antimicrobial peptides, magainin 2 and PGLa, in liposomes (1999) (0)
Structure-Activity Relationship Study of Neurokinin-3 Receptor Agonists (2013) (0)
Application of Ring Closing Olefin Metathesis to the Conformational Restriction of Biologically Active Peptide. Part 1 (2000) (0)
Development of Chemical Probes for the Chemokine Receptor CXCR4 Involving Radiolabeled T140 Analogs (2007) (0)
Synthesis and Biological Activity of Bombesin Analogues Containing (E)-Alkene Dipeptide Isosteres (1995) (0)
Direct Synthesis of Highly Fused Perimidines by Copper(I)‐Catalyzed Hydroamination of 2‐Ethynylbenzaldehydes. (2011) (0)

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