Nobutaka Hattori
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Computer Science
Nobutaka Hattori's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Nobutaka Hattori's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism (1998) (4916)
- Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase (2000) (2014)
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy (2010) (1603)
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease (2009) (1235)
- Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease (2001) (1064)
- An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin (2001) (1036)
- Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. (1996) (960)
- Etiology and Pathogenesis of Parkinson’s Disease (2011) (916)
- Protein-bound acrolein: potential markers for oxidative stress. (1998) (595)
- Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. (1999) (539)
- Mitochondrial genome variation in eastern Asia and the peopling of Japan. (2004) (525)
- Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. (2006) (505)
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy (2012) (495)
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria (2012) (436)
- p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria (2010) (406)
- Cerebral organoids model human brain development and microcephaly (2014) (373)
- A rotarod test for evaluation of motor skill learning (2010) (370)
- Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition (2011) (367)
- LRRK2 regulates synaptic vesicle endocytosis. (2008) (350)
- Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria (2012) (334)
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue (2012) (328)
- Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. (2002) (325)
- Methylglyoxal Modification of Protein (1999) (295)
- Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals (1998) (293)
- Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in parkinson's disease (1991) (279)
- Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients (1999) (269)
- Clinical heterogeneity of α‐synuclein gene duplication in Parkinson's disease (2006) (265)
- CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study (2015) (265)
- Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin‐like domain (2003) (258)
- Mutations in COQ2 in familial and sporadic multiple-system atrophy. (2013) (246)
- Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. (2005) (246)
- Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study (2011) (246)
- Genomic investigation of α‐synuclein multiplication and parkinsonism (2008) (231)
- Novel PINK1 mutations in early‐onset parkinsonism (2004) (228)
- TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation. (2015) (225)
- Clinicopathological features of Churg-Strauss syndrome-associated neuropathy. (1999) (218)
- Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease. (2006) (211)
- Pathology of early- vs late-onset TTR Met30 familial amyloid polyneuropathy (2004) (200)
- Fabrication, characterization, and application of boron-doped diamond microelectrodes for in vivo dopamine detection. (2007) (196)
- Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease (2008) (191)
- Mutations for Gaucher disease confer high susceptibility to Parkinson disease. (2009) (187)
- PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy (2010) (185)
- Diverse Effects of Pathogenic Mutations of Parkin That Catalyze Multiple Monoubiquitylation in Vitro* (2006) (185)
- Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke (2017) (184)
- Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease. (2006) (183)
- Identification of novel biomarkers for Parkinson's disease by metabolomic technologies (2015) (179)
- Mutations in Fis1 disrupt orderly disposal of defective mitochondria (2014) (177)
- An immunohistochemical study on α‐ketoglutarate dehydrogenase complex in Parkinson's disease (1994) (175)
- UCHL1 is a Parkinson's disease susceptibility gene (2004) (173)
- Role of mitochondria in the etiology and pathogenesis of Parkinson's disease. (1995) (172)
- Effect of Wild-type or Mutant Parkin on Oxidative Damage, Nitric Oxide, Antioxidant Defenses, and the Proteasome* (2002) (172)
- Late-onset familial amyloid polyneuropathy type I (transthyretin Met30-associated familial amyloid polyneuropathy) unrelated to endemic focus in Japan. Clinicopathological and genetic features. (1999) (169)
- A Combinatorial Code for the Interaction of α-Synuclein with Membranes* (2005) (162)
- Point Mutations (Thr240Arg and Ala311Stop) in theParkinGene (1998) (161)
- Increased 8‐oxo‐dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease (1999) (160)
- Sept4, a Component of Presynaptic Scaffold and Lewy Bodies, Is Required for the Suppression of α-Synuclein Neurotoxicity (2007) (153)
- Leucine-rich repeat kinase 2 associates with lipid rafts. (2007) (147)
- Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism (2005) (147)
- Exendin-4, a glucagon-like peptide-1 receptor agonist, provides neuroprotection in mice transient focal cerebral ischemia (2011) (145)
- Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism (2010) (143)
- Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering (2014) (139)
- Pathogenetic mechanisms of parkin in Parkinson's disease (2004) (133)
- Large-scale replication and heterogeneity in Parkinson disease genetic loci (2012) (133)
- Painful alcoholic polyneuropathy with predominant small-fiber loss and normal thiamine status (2001) (133)
- Leucine-Rich Repeat kinase 2 G2385R variant is a risk factor for Parkinson disease in Asian population (2007) (132)
- Prognosis of Parkinson's disease: Time to stage III, IV, V, and to motor fluctuations (2006) (132)
- Parkin is associated with cellular vesicles (2001) (131)
- AFQ056 in Parkinson patients with levodopa‐induced dyskinesia: 13‐week, randomized, dose‐finding study (2013) (130)
- Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys (1994) (130)
- Expanding the clinical phenotype of SNCA duplication carriers (2009) (127)
- Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries (2006) (122)
- Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson’s disease and related neurodegenerative disorders (2005) (120)
- Pilot study of H2 therapy in Parkinson's disease: A randomized double‐blind placebo‐controlled trial (2013) (118)
- Ubiquitin, proteasome and parkin. (2004) (118)
- Parkin attenuates manganese‐induced dopaminergic cell death (2004) (115)
- Parkin and Parkinson's disease (2001) (115)
- Lithium and autophagy. (2014) (114)
- Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease (2005) (113)
- 14‐3‐3η is a novel regulator of parkin ubiquitin ligase (2006) (111)
- Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth (2009) (110)
- Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c (2016) (106)
- A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants (2012) (105)
- Parkinson’s Disease with and without REM Sleep Behaviour Disorder: Are There Any Clinical Differences? (2009) (104)
- Siah-1 Facilitates Ubiquitination and Degradation of Synphilin-1* (2003) (102)
- Pathogenesis of familial Parkinson’s disease: new insights based on monogenic forms of Parkinson’s disease (2009) (102)
- Polymorphism of the Lipoprotein Lipase Gene and Risk of Atherothrombotic Cerebral Infarction in the Japanese (2001) (101)
- Chronic intermittent hypoxia/reoxygenation facilitate amyloid-β generation in mice. (2013) (99)
- Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology (2015) (99)
- Postgastrectomy polyneuropathy with thiamine deficiency (2001) (98)
- Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations. (2006) (98)
- A combinatorial code for the interaction of alpha-synuclein with membranes. (2005) (98)
- Variants associated with Gaucher disease in multiple system atrophy (2015) (97)
- Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease (2018) (95)
- Polymorphism in the parkin gene in sporadic Parkinson's disease (1999) (94)
- Neurite orientation dispersion and density imaging in the substantia nigra in idiopathic Parkinson disease (2016) (93)
- PARK9-LINKED PARKINSONISM IN EASTERN ASIA: MUTATION DETECTION IN ATP13A2 AND CLINICAL PHENOTYPE (2008) (91)
- FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis (2015) (90)
- Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families (2007) (90)
- Parkinson's disease in the Western Pacific Region (2019) (90)
- An axonal form of Charcot-Marie-Tooth disease showing distinctive features in association with mutations in the peripheral myelin protein zero gene (Thr124Met or Asp75Val) (2000) (89)
- Preserved cardiac sympathetic nerve accounts for normal cardiac uptake of MIBG in PARK2 (2005) (88)
- Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines. (2010) (88)
- Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population (2008) (87)
- A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging (2014) (86)
- Phosphodiesterase III Inhibition Promotes Differentiation and Survival of Oligodendrocyte Progenitors and Enhances Regeneration of Ischemic White Matter Lesions in the Adult Mammalian Brain (2010) (85)
- White Matter Alteration of the Cingulum in Parkinson Disease with and without Dementia: Evaluation by Diffusion Tensor Tract–Specific Analysis (2012) (85)
- Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study. (2003) (85)
- Neuropathic pain correlates with myelinated fibre loss and cytokine profile in POEMS syndrome (2008) (84)
- Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila (2017) (84)
- Genetic mutations and functions of PINK1. (2011) (84)
- CLINICOPATHOLOGIC STUDY OF A SNCA GENE DUPLICATION PATIENT WITH PARKINSON DISEASE AND DEMENTIA (2008) (83)
- Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice (2018) (83)
- Familial Parkinson's disease. Alpha-synuclein and parkin. (2001) (83)
- Progress in the pathogenesis and genetics of Parkinson's disease (2008) (82)
- Parkin stabilizes PINK1 through direct interaction. (2009) (82)
- Mitochondrial dysfunction in parkinson's disease (1998) (81)
- Spinal cord magnetic resonance imaging demonstrates sensory neuronal involvement and clinical severity in neuronopathy associated with Sjögren's syndrome (2001) (80)
- The LRRK2 I2012T, G2019S, and I2020T mutations are rare in Taiwanese patients with sporadic Parkinson's disease. (2005) (80)
- Autosomal recessive early-onset parkinsonism with diurnal fluctuation: clinicopathologic characteristics and molecular genetic identification (2000) (79)
- Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease (2017) (78)
- Mutation analysis of the PINK1 gene in 391 patients with Parkinson disease. (2008) (78)
- Motor and non-motor symptoms of 1453 patients with Parkinson's disease: prevalence and risks. (2013) (76)
- Diffusional kurtosis imaging of cingulate fibers in Parkinson disease: comparison with conventional diffusion tensor imaging. (2013) (76)
- Molecular pathogenesis of Parkinson's disease: update (2011) (74)
- Parkin is linked to the ubiquitin pathway (2001) (74)
- VPS35 mutation in Japanese patients with typical Parkinson's disease (2012) (74)
- Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS. (2013) (74)
- A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease (2011) (74)
- Impact of diabetes and prediabetes on the short-term prognosis in patients with acute ischemic stroke (2013) (73)
- Increased Lysosomal Exocytosis Induced by Lysosomal Ca2+ Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity (2019) (72)
- Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion (2012) (72)
- Relationship between cognitive impairment and white-matter alteration in Parkinson’s disease with dementia: tract-based spatial statistics and tract-specific analysis (2013) (72)
- PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations (2004) (71)
- Gray Matter Abnormalities in Idiopathic Parkinson's Disease: Evaluation by Diffusional Kurtosis Imaging and Neurite Orientation Dispersion and Density Imaging (2017) (71)
- Ataxic vs painful form of paraneoplastic neuropathy (2007) (71)
- Parkin Cleaves Intracellular α-Synuclein Inclusions via the Activation of Calpain* (2003) (71)
- LRRK2 I2020T mutation is associated with tau pathology. (2012) (70)
- Neurochemical and Neurogenetic Correlates of Parkinson's Disease (1998) (69)
- Clinical and electrophysiologic correlates of IVIg responsiveness in CIDP (2005) (69)
- Axonal and perikaryal involvement in chronic inflammatory demyelinating polyneuropathy (1999) (69)
- Screening PARK genes for mutations in early-onset Parkinson's disease patients from Queensland, Australia. (2009) (68)
- Perlecan is required for FGF-2 signaling in the neural stem cell niche. (2014) (67)
- Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects (2011) (66)
- ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint‐like inclusion body formation, and selective degeneration of dopaminergic neurons (2013) (65)
- Age associated axonal features in HNPP with 17p11.2 deletion in Japan (2005) (65)
- Segmental Zoster Paresis of Limbs: Report of Three Cases and Review of Literature (2007) (65)
- Diffusional kurtosis imaging of normal-appearing white matter in multiple sclerosis: preliminary clinical experience (2012) (65)
- Iron accumulation in the substantia nigra of autosomal recessive juvenile parkinsonism (ARJP). (2001) (65)
- Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene. (1998) (64)
- Clinicogenetic study of GBA mutations in patients with familial Parkinson's disease (2014) (64)
- Homozygous alpha-synuclein p.A53V in familial Parkinson's disease (2017) (62)
- PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila (2014) (62)
- Neuropsychiatric and cognitive features in autosomal‐recessive early parkinsonism due to PINK1 mutations (2007) (60)
- T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease (2018) (60)
- L-Carnitine Enhances Axonal Plasticity and Improves White-Matter Lesions after Chronic Hypoperfusion in Rat Brain (2015) (60)
- Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease. (2015) (60)
- A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism (2018) (60)
- Expression of Glucose Transporters in Rat Brain Following Transient Focal Ischemic Injury (1996) (59)
- An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease. (1994) (59)
- Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum (2014) (59)
- Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins. (2015) (59)
- Effects of UCH‐L1 on α‐synuclein over‐expression mouse model of Parkinson’s disease (2009) (59)
- Genotype in the 24-kDa subunit gene (NDUFV2) of mitochondrial complex I and susceptibility to Parkinson disease. (1998) (59)
- Parkin-Mediated Protection of Dopaminergic Neurons in a Chronic MPTP-Minipump Mouse Model of Parkinson Disease (2011) (59)
- Parkin and Endoplasmic Reticulum Stress (2003) (58)
- Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease (2014) (57)
- Prevalence of Abnormal Glucose Metabolism and Insulin Resistance Among Subtypes of Ischemic Stroke in Japanese Patients (2009) (57)
- Electrophysiological features of late-onset transthyretin Met30 familial amyloid polyneuropathy unrelated to endemic foci (2008) (57)
- Decline of striatal dopamine release in parkin‐deficient mice shown by ex vivo autoradiography (2006) (57)
- Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells (2005) (57)
- A metabolic profile of polyamines in parkinson disease: A promising biomarker (2019) (57)
- Excessive daytime sleepiness and sleep episodes in Japanese patients with Parkinson's disease (2008) (57)
- Plasmablasts as Migratory IgG-Producing Cells in the Pathogenesis of Neuromyelitis Optica (2013) (57)
- Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain (2000) (56)
- Laminin α1 is essential for mouse cerebellar development. (2012) (56)
- MR Biomarkers of Degenerative Brain Disorders Derived From Diffusion Imaging (2019) (56)
- Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition. (2010) (56)
- The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway (2015) (55)
- Neuronal intranuclear hyaline inclusion disease showing motor-sensory and autonomic neuropathy (2005) (55)
- Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease (2007) (55)
- Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders (2015) (55)
- Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy (2018) (54)
- Posterior hypoperfusion in parkinson's disease With and without dementia measured with arterial spin labeling MRI (2011) (54)
- Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease (2018) (54)
- Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase (2018) (54)
- New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism (2003) (54)
- Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. (2017) (53)
- Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice. (2015) (52)
- Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia (2010) (52)
- Toward identification of susceptibility genes for sporadic Parkinson’s disease (2003) (52)
- Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins (1997) (52)
- The effects of A1/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion (2020) (51)
- Calbindin 1, fibroblast growth factor 20, and α-synuclein in sporadic Parkinson’s disease (2008) (51)
- Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation (2019) (51)
- Correlation between depressive symptoms and nocturnal disturbances in Japanese patients with Parkinson's disease. (2009) (50)
- Impaired in vivo dopamine release in parkin knockout mice (2010) (50)
- Intravenous immunoglobulin treatment in painful sensory neuropathy without sensory ataxia associated with Sjögren’s syndrome (2006) (50)
- Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson’s disease (2006) (50)
- Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling (2019) (50)
- PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism. (2000) (50)
- DNAJC12 and dopa‐responsive nonprogressive parkinsonism (2017) (50)
- Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment (2018) (50)
- The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties. (2015) (50)
- Variants in saposin D domain of prosaposin gene linked to Parkinson's disease. (2020) (49)
- Accumulation of somatic mutation in mitochondrial DNA extracted from peripheral blood cells in diabetic patients (2002) (49)
- Autosomal-recessive juvenile parkinsonism in a Jewish Yemenite kindred: mutation of Parkin gene. (1999) (49)
- Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance. (2013) (49)
- Improvements in both psychosis and motor signs in Parkinson's disease, and changes in regional cerebral blood flow after electroconvulsive therapy (2011) (48)
- Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans. (2010) (48)
- An Essential Role of the Intraparietal Sulcus in Response Inhibition Predicted by Parcellation-Based Network (2019) (48)
- A microdeletion of D6S305 in a family of autosomal recessive juvenile parkinsonism (PARK2). (1998) (48)
- Familial Parkinsonism with digenic parkin and PINK1 mutations (2008) (48)
- Rotigotine vs ropinirole in advanced stage Parkinson's disease: a double-blind study. (2014) (48)
- Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells (2017) (48)
- Demographic, clinical, and radiologic predictors of neurologic deterioration in patients with acute ischemic stroke. (2013) (47)
- Mitochondrial dysfunction in Parkinson's disease. (2002) (47)
- Recessive Parkinson's disease (2006) (46)
- Exendin-4 Inhibits Matrix Metalloproteinase-9 Activation and Reduces Infarct Growth After Focal Cerebral Ischemia in Hyperglycemic Mice (2016) (46)
- Characteristics of sleep disturbances in Japanese patients with Parkinson's disease. A study using Parkinson's disease sleep scale (2007) (46)
- Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration. (2002) (45)
- Regulation by mitophagy. (2014) (45)
- Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism: First case report (2005) (44)
- Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling (2016) (44)
- PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation (2014) (43)
- Astrocytes Protect Human Dopaminergic Neurons from α-Synuclein Accumulation and Propagation (2020) (43)
- Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra (2008) (43)
- Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice (2019) (43)
- High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism (2015) (43)
- Chronic inflammatory demyelinating polyneuropathy presenting with features of GBS. (2002) (43)
- Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution (2017) (43)
- Lewy body pathology in a patient with a homozygous Parkin deletion (2013) (42)
- Impact of sleep-related symptoms on clinical motor subtypes and disability in Parkinson’s disease: a multicentre cross-sectional study (2017) (42)
- Neuropathologic analysis of Lewy‐related α‐synucleinopathy in olfactory mucosa (2013) (42)
- Fatigue in Japanese patients with Parkinson's disease: A study using Parkinson fatigue scale (2009) (42)
- Camptocormia, axial dystonia, and parkinsonism: Phenotypic heterogeneity of a parkin mutation (2003) (41)
- Haploinsufficiency at the α‐synuclein gene underlies phenotypic severity in familial Parkinson’s disease (2003) (41)
- The effect of Ndrg2 expression on astroglial activation (2011) (41)
- Extensive hemispheric lesions with radiological evidence of blood–brain barrier integrity in a patient with neuromyelitis optica (2009) (41)
- NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization (2014) (41)
- Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson’s disease (2016) (40)
- Evaluation of the efficacy of pramipexole for treating levodopa-induced dyskinesia in patients with Parkinson's disease. (2013) (40)
- Effects of Pioglitazone for Secondary Stroke Prevention in Patients with Impaired Glucose Tolerance and Newly Diagnosed Diabetes: The J-SPIRIT Study. (2015) (40)
- Mobile Aortic Plaques Are a Cause of Multiple Brain Infarcts Seen on Diffusion-Weighted Imaging (2007) (40)
- Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells. (2005) (40)
- Catechol-O-methyltransferase genotype and susceptibility to Parkinson's disease in Japan (2005) (40)
- Acute effects of bilateral subthalamic stimulation on decision-making in Parkinson's disease. (2011) (40)
- Mechanism and treatment of dropped head syndrome associated with parkinsonism. (2009) (40)
- Unmet Needs of Patients with Parkinson's Disease: Interview Survey of Patients and Caregivers (2009) (39)
- Parkin absence accelerates microtubule aging in dopaminergic neurons (2018) (39)
- Population‐specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO‐PD) consortium (2013) (39)
- Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction (2018) (39)
- Progress in the clinical and molecular genetics of familial parkinsonism (2000) (39)
- Visual impairment in Parkinson's disease treated with amantadine: case report and review of the literature. (2008) (39)
- FBXO7 mutations in Parkinson's disease and multiple system atrophy (2016) (39)
- Erratum: UCHL1 is a Parkinson's disease susceptibility gene (Annals of Neurology (April 2004) 55 (512-521)) (2004) (38)
- An immunohistochemical study on manganese superoxide dismutase in Parkinson's disease (1997) (38)
- Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain. (2003) (38)
- Sjögren’s syndrome associated painful sensory neuropathy without sensory ataxia (2003) (38)
- A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis (2020) (38)
- Clinical manifestations of nonmotor symptoms in 1021 Japanese Parkinson's disease patients from 35 medical centers. (2017) (38)
- Parkin gene causing benign autosomal recessive juvenile parkinsonism (2001) (38)
- Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone. (2019) (38)
- Extensive aggregation of α-synuclein and tau in juvenile-onset neuroaxonal dystrophy: an autopsied individual with a novel mutation in the PLA2G6 gene-splicing site (2013) (37)
- Collaborative Analysis of (cid:1) -Synuclein Gene Promoter Variability and Parkinson Disease (2006) (37)
- Autosomal recessive juvenile parkinsonism: A key to understanding nigral degeneration in sporadic Parkinson's disease (2000) (37)
- Neurite orientation dispersion and density imaging of the nigrostriatal pathway in Parkinson's disease: Retrograde degeneration observed by tract-profile analysis. (2018) (37)
- The frequency of cardiac valvular regurgitation in Parkinson's disease (2008) (37)
- Influenza-associated MOG antibody-positive longitudinally extensive transverse myelitis: a case report (2014) (36)
- Parkin regulates kainate receptors by interacting with the GluK2 subunit (2014) (36)
- Establishing diagnostic criteria for Perry syndrome (2017) (35)
- Iron Supply via NCOA4-Mediated Ferritin Degradation Maintains Mitochondrial Functions (2019) (35)
- Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease (2020) (35)
- PLA2G6 variant in Parkinson's disease (2011) (35)
- Official Japanese Version of the International Parkinson and Movement Disorder Society–Unified Parkinson's Disease Rating Scale: Validation Against the Original English Version (2014) (35)
- Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice. (2016) (34)
- The protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants (2014) (34)
- Metabolomics‐based identification of metabolic alterations in PARK2 (2019) (34)
- Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle (2018) (34)
- Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population (2007) (34)
- Primary skeletal muscle involvement in chorea‐acanthocytosis (2007) (33)
- Absence of Lewy pathology associated with PINK1 homozygous mutation (2016) (33)
- Programmed cell death‐2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease (2009) (33)
- Gabapentin enacarbil in Japanese patients with restless legs syndrome: a 12-week, randomized, double-blind, placebo-controlled, parallel-group study (2013) (32)
- Twin CHCH Proteins, CHCHD2, and CHCHD10: Key Molecules of Parkinson’s Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia (2019) (32)
- Patent Foramen Ovale with Atrial Septal Aneurysm May Contribute to White Matter Lesions in Stroke Patients (2010) (32)
- Mutations in CHCHD2 cause α-synuclein aggregation. (2019) (32)
- Sensory neuropathy in autosomal recessive juvenile parkinsonism (PARK2). (2003) (32)
- Long-term efficacy and safety of gabapentin enacarbil in Japanese restless legs syndrome patients (2012) (32)
- Cerebral Microbleeds Are Associated with Worse Cognitive Function in the Nondemented Elderly with Small Vessel Disease (2014) (32)
- Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia (2020) (31)
- Transdermal rotigotine in advanced Parkinson’s disease: a randomized, double-blind, placebo-controlled trial (2014) (31)
- YY1 binds to α-synuclein 3′-flanking region SNP and stimulates antisense noncoding RNA expression (2013) (31)
- Pembrolizumab-related systemic myositis involving ocular and hindneck muscles resembling myasthenic gravis: a case report (2019) (31)
- Accumulation of Somatic Mutation in Mitochondrial DNA and Atherosclerosis in Diabetic Patients (2004) (30)
- ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout (2015) (30)
- Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations (2018) (30)
- Bacteria–Host Interactions in Multiple Sclerosis (2018) (30)
- Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson’s disease (2005) (30)
- Twenty years since the discovery of the parkin gene (2017) (30)
- Age-related effects and gender differences in Japanese healthy controls for [123I] FP-CIT SPECT (2017) (30)
- Neuromelanin imaging and midbrain volumetry in progressive supranuclear palsy and Parkinson's disease (2018) (30)
- Efficacy and Safety of Extended- Versus Immediate-Release Pramipexole in Japanese Patients With Advanced and L-dopa–Undertreated Parkinson Disease: A Double-Blind, Randomized Trial (2012) (30)
- Anticipation in early- but not late-onset familial amyloid polyneuropathy (TTR Met 30) in Japan (2000) (30)
- Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier (2007) (30)
- Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1 (2014) (30)
- Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease (2011) (30)
- Effect of istradefylline on mood disorders in Parkinson's disease (2019) (30)
- Colocalization of Bcl-2 and 4-hydroxynonenal modified proteins in microglial cells and neurons of rat brain following transient focal ischemia (1998) (30)
- A clinical predictive score for postoperative myasthenic crisis (2017) (29)
- Cerebral infarcts associated with adenomyosis among middle-aged women. (2012) (29)
- Efficacy and safety of safinamide as an add-on therapy to L-DOPA for patients with Parkinson's disease: A randomized, double-blind, placebo-controlled, phase II/III study. (2020) (29)
- Neuroprotective effects of memantine via enhancement of autophagy. (2019) (29)
- The prevalence and risk factors of cerebral microbleeds in patients with Parkinson's disease. (2015) (29)
- Posterior cortical atrophy with [11C] Pittsburgh compound B accumulation in the primary visual cortex (2010) (28)
- Free-Water Imaging in White and Gray Matter in Parkinson’s Disease (2019) (28)
- Progress in familial Parkinson's disease. (2006) (28)
- Alterations in Nitric Oxide and Endothelin-1 Bioactivity Underlie Cerebrovascular Dysfunction in ApoE-Deficient Mice (2010) (28)
- Mutation analyses in amyotrophic lateral sclerosis/parkinsonism–dementia complex of the Kii peninsula, Japan (2008) (28)
- Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy (2020) (28)
- Lipids: Key Players That Modulate α-Synuclein Toxicity and Neurodegeneration in Parkinson’s Disease (2020) (28)
- TBK 1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p 62 / SQSTM 1 phosphorylation (2015) (28)
- Bispecific abs against modified protein and DNA with oxidized lipids. (2006) (28)
- An exploratory study of the efficacy and safety of yokukansan for neuropsychiatric symptoms in patients with Parkinson’s disease (2014) (27)
- Dominant‐negative effect of mutant valosin‐containing protein in aggresome formation (2006) (27)
- Positive immunoreactivity for vesicular monoamine transporter 2 in Lewy bodies and Lewy neurites in substantia nigra (2006) (27)
- The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO and Alters Dopaminergic Neuron Survival in Drosophila (2012) (27)
- Quantitative evaluation of electroconvulsive therapy for Parkinson’s disease with refractory psychiatric symptoms (2014) (27)
- Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice. (2016) (26)
- Subacute longitudinal myelitis associated with Behcet's disease. (2010) (26)
- Development of new fusion proteins for visualizing amyloid-β oligomers in vivo (2016) (26)
- Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD (2010) (26)
- Management of impulse control disorders with deep brain stimulation: A double-edged sword (2017) (26)
- MR g-ratio-weighted connectome analysis in patients with multiple sclerosis (2019) (26)
- Suitable indications of eculizumab for patients with refractory generalized myasthenia gravis (2020) (26)
- Clinical course of the first Asian family with Parkinsonism related to SNCA triplication (2010) (26)
- Protein Kinase A-Dependent Suppression of Reactive Oxygen Species in Transient Focal Ischemia in Adrenomedullin-Deficient Mice (2009) (26)
- Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson’s disease patients (2019) (26)
- Transdermal rotigotine in early stage Parkinson's disease: A randomized, double‐blind, placebo‐controlled trial (2013) (25)
- Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain. (1995) (25)
- Successful treatment of relapsing neuro-Sweet's disease with corticosteroid and dapsone combination therapy (2007) (25)
- MDSGene: Closing Data Gaps in Genotype-Phenotype Correlations of Monogenic Parkinson’s Disease (2018) (25)
- VPS29–VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process (2015) (25)
- Neuroprotective role of angiotensin II type 2 receptor after transient focal ischemia in mice brain (2008) (25)
- Aging, Aortic Arch Calcification, and Multiple Brain Infarcts Are Associated with Aortogenic Brain Embolism (2013) (25)
- Rosuvastatin may stabilize atherosclerotic aortic plaque: transesophageal echocardiographic study in the EPISTEME trial. (2015) (24)
- Cerebral infarction in a young man using high-dose anabolic steroids. (2012) (24)
- Human-Derived Physiological Heat Shock Protein 27 Complex Protects Brain after Focal Cerebral Ischemia in Mice (2013) (24)
- Efficacy, safety and risk of augmentation of rotigotine for treating restless legs syndrome (2013) (24)
- Familial Parkinson’s disease: a hint to elucidate the mechanisms of nigral degeneration (2003) (24)
- Reversible cerebral vasoconstriction syndrome presenting as subarachnoid hemorrhage, reversible posterior leukoencephalopathy, and cerebral infarction. (2011) (24)
- The parkin gene S/N167 polymorphism in Australian Parkinson's disease patients and controls. (2001) (24)
- Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy. (2008) (23)
- Convolutional neural network-based segmentation can help in assessing the substantia nigra in neuromelanin MRI (2019) (23)
- Large-scale assessment of polyglutamine repeat expansions in Parkinson disease (2015) (23)
- Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites (2020) (23)
- MRI findings in the mild type of mucopolysaccharidosis II (Hunter's syndrome) (2004) (23)
- Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease. (2000) (23)
- Asian perspectives on the recognition and management of levodopa ‘wearing-off’ in Parkinson’s disease (2015) (23)
- Pathophysiological dual action of adiponectin after transient focal ischemia in mouse brain (2009) (23)
- Validity of Single Tract Microelectrode Recording in Subthalamic Nucleus Stimulation (2013) (23)
- Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice (2016) (23)
- Golden mean to longevity: Rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease (2002) (22)
- Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains (2009) (22)
- SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo (2020) (22)
- GCH1 mutations in dopa-responsive dystonia and Parkinson’s disease (2018) (22)
- A Randomized Crossover Pilot Study of Telemedicine Delivered via iPads in Parkinson's Disease (2019) (22)
- Nonmotor Symptoms in Patients with PARK2 Mutations (2011) (22)
- Patient perspectives on Parkinson’s disease therapy in Japan and the United States: results of two patient surveys (2012) (21)
- Comparison of clinical backgrounds with anterior versus posterior circulation infarcts. (2010) (21)
- LRRK2 P755L variant in sporadic Parkinson's disease (2008) (21)
- A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics (2016) (21)
- Identification of a Japanese family with LRRK2 p.R1441G-related Parkinson's disease (2014) (21)
- Animal models of Parkinson's disease: Similarities and differences between the disease and models (2007) (21)
- Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice (2020) (21)
- Randomized, double‐blind, multicenter trial of hydrogen water for Parkinson's disease (2018) (21)
- Current Topics in Deep Brain Stimulation for Parkinson Disease (2016) (21)
- Adequate Adherence to Direct Oral Anticoagulant is Associated with Reduced Ischemic Stroke Severity in Patients with Atrial Fibrillation. (2019) (21)
- Discovery and in vitro and in vivo profiles of N-ethyl-N-[2-[3-(5-fluoro-2-pyridinyl)-1H-pyrazol-1-yl]ethyl]-2-(2H-1,2,3-triazol-2-yl)-benzamide as a novel class of dual orexin receptor antagonist. (2015) (21)
- DJ-1 associates with synaptic membranes (2011) (21)
- Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study (2019) (20)
- Associations of durations of antiplatelet use and vascular risk factors with the presence of cerebral microbleeds. (2013) (20)
- A TREX1 mutation causing cerebral vasculopathy in a patient with familial chilblain lupus (2013) (20)
- An Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in Aged Monkeys: Reduction in Plaque Amyloid and Increase in Aβ Oligomers. (2016) (20)
- Art and Parkinson’s disease: a dramatic change in an artist’s style as an initial symptom (2011) (20)
- Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease. (2003) (20)
- Characterizing restless legs syndrome and leg motor restlessness in patients with Parkinson's disease: A multicenter case-controlled study. (2017) (20)
- Functional Organization for Response Inhibition in the Right Inferior Frontal Cortex of Individual Human Brains (2020) (20)
- Lysine 63-linked Polyubiquitination Is Dispensable for Parkin-mediated Mitophagy* (2014) (20)
- Neuromelanin MRI is useful for monitoring motor complications in Parkinson’s and PARK2 disease (2017) (20)
- Ectopic expression of α‐synuclein affects the migration of neural stem cells in mouse subventricular zone (2010) (20)
- Hoarseness due to bilateral vocal cord paralysis as an initial manifestation of familial amyotrophic lateral sclerosis (2005) (20)
- Anti-Mycobacterial Antibodies in Paired Cerebrospinal Fluid and Serum Samples from Japanese Patients with Multiple Sclerosis or Neuromyelitis Optica Spectrum Disorder (2018) (20)
- Neuromyelitis optica spectrum disorder after treatment with pembrolizumab. (2019) (20)
- Role of the Gut Microbiota in Stroke Pathogenesis and Potential Therapeutic Implications (2021) (20)
- Prevalence of GJB2 causing recessive profound non-syndromic deafness in Japanese children. (2011) (20)
- Catechol-O-methyltransferase genotype and susceptibility to Parkinson's disease in Japan. Short communication. (1997) (20)
- Genetics of Parkinson's disease. (1999) (20)
- Prognosis of amyotrophic lateral sclerosis patients undergoing tracheostomy invasive ventilation therapy in Japan (2020) (20)
- Conflicting Role of Mycobacterium Species in Multiple Sclerosis (2017) (20)
- Randomized, Controlled Study of Opicapone in Japanese Parkinson's Patients with Motor Fluctuations (2020) (19)
- Benefits of prestroke use of angiotensin type 1 receptor blockers on ischemic stroke severity. (2012) (19)
- NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy (2018) (19)
- Glucose metabolism in cholinoceptive cortical ratbrain regions after basal forebrain cholinergic lesion (1998) (19)
- Myelin Measurement Using Quantitative Magnetic Resonance Imaging: A Correlation Study Comparing Various Imaging Techniques in Patients with Multiple Sclerosis (2020) (19)
- A LRRK2 G2019S mutation carrier from Turkey shares the Japanese haplotype (2009) (19)
- Identification of Licopyranocoumarin and Glycyrurol from Herbal Medicines as Neuroprotective Compounds for Parkinson's Disease (2014) (19)
- A Randomized Double-Blind Placebo-Controlled Phase III Trial of Selegiline Monotherapy for Early Parkinson Disease (2017) (19)
- Cerebral infarction developing in a patient without cancer with a markedly elevated level of mucinous tumor marker. (2012) (19)
- Protective Role of Levetiracetam Against Cognitive Impairment And Brain White Matter Damage in Mouse prolonged Cerebral Hypoperfusion (2019) (19)
- Genetic and environmental factors in the pathogenesis of Parkinson's disease. (1999) (19)
- An apparently sporadic case with parkin gene mutation in a Korean woman. (2001) (18)
- Pramipexole reduces the prevalence of fatigue in patients with Parkinson's disease. (2011) (18)
- Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice (2011) (18)
- Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains (2013) (18)
- Nonmercaptalbumin as an oxidative stress marker in Parkinson’s and PARK2 disease (2020) (18)
- What is the evidence to support home environmental adaptation in Parkinson's disease? A call for multidisciplinary interventions. (2015) (18)
- Posterior reversible encephalopathy syndrome induced after blood transfusion for severe anemia (2013) (18)
- Emerging Risk Factors for Recurrent Vascular Events in Patients With Embolic Stroke of Undetermined Source (2016) (18)
- Genotype–phenotype correlation: Familial Parkinson disease (2003) (18)
- A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling (2020) (18)
- Pseudo-autosomal dominant inheritance of PARK2: two families with parkin gene mutations (2003) (18)
- Gray Matter Alterations in Early and Late Relapsing-Remitting Multiple Sclerosis Evaluated with Synthetic Quantitative Magnetic Resonance Imaging (2019) (18)
- Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations (2020) (18)
- New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers (2019) (18)
- [Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease]. (2004) (17)
- Mitochondrial energy crisis in Parkinson's disease. (1993) (17)
- Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases (2016) (17)
- Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson’s Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Placebo-Controlled MOVES-PD Trial (2021) (17)
- Rationale and Design of the Carotid Plaque in Human for All Evaluations With Aggressive Rosuvastatin Therapy (CHALLENGER Trial) (2009) (17)
- Brain tissue and myelin volumetric analysis in multiple sclerosis at 3T MRI with various in-plane resolutions using synthetic MRI (2019) (17)
- Involvement of the caudate nucleus head and its networks in sporadic amyotrophic lateral sclerosis-frontotemporal dementia continuum (2016) (17)
- Efficacy and safety of rotigotine in Japanese patients with restless legs syndrome: a phase 3, multicenter, randomized, placebo-controlled, double-blind, parallel-group study. (2013) (17)
- Developmental changes in the expression of parkin and UbcR7, a parkin‐interacting and ubiquitin‐conjugating enzyme, in rat brain (2001) (17)
- FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice (2016) (17)
- Familial Parkinsonism with Apathy, Depression and Central Hypoventilation (Perry’s Syndrome) (2002) (16)
- Rasagiline monotherapy in early Parkinson's disease: A phase 3, randomized study in Japan. (2019) (16)
- Parkinsonism Relating to Intoxication with Glyphosate (2019) (16)
- Clinical heterogeneity of frontotemporal dementia and Parkinsonism linked to chromosome 17 caused by MAPT N279K mutation in relation to tau positron emission tomography features (2019) (16)
- Longitudinal myelitis caused by visceral larva migrans associated with Toxocara cati infection: Case report (2012) (16)
- Patent foramen ovale and atrial septal aneurysm can cause ischemic stroke in patients with antiphospholipid syndrome (2012) (16)
- Age Stratification and Impact of Eicosapentaenoic Acid and Docosahexaenoic Acid to Arachidonic Acid Ratios in Ischemic Stroke Patients (2017) (16)
- First report of a Japanese family with spinocerebellar ataxia type 10: The second report from Asia after a report from China (2017) (16)
- Cytomegalovirus-associated encephalomyelitis in an immunocompetent adult: a two-stage attack of direct viral and delayed immune-mediated invasions. case report (2016) (16)
- Delivering patient-centered care in Parkinson's disease: Challenges and consensus from an international panel. (2020) (16)
- Clinical and radiological CLIPPERS features after complete remission of peripheral T-cell lymphoma, not otherwise specified (2016) (16)
- A case of α‐synuclein gene duplication presenting with head‐shaking movements (2013) (16)
- The Risk Factors for the Wearing-off Phenomenon in Parkinson's Disease in Japan: A Cross-sectional, Multicenter Study (2017) (16)
- Charcot-Marie-Tooth families in Japan with MPZ Thr124Met mutation (2004) (16)
- Urinary homocysteic acid levels correlate with mini-mental state examination scores in Alzheimer's disease patients. (2012) (16)
- Humoral response against host-mimetic homologous epitopes of Mycobacterium avium subsp. paratuberculosis in Japanese multiple sclerosis patients (2016) (16)
- PARK2 mutations and clinical features in a Chinese population with early-onset Parkinson’s disease (2008) (15)
- The Effects of Astrocyte and Oligodendrocyte Lineage Cell Interaction on White Matter Injury under Chronic Cerebral Hypoperfusion (2019) (15)
- Closed-loop programming using external responses for deep brain stimulation in Parkinson's disease. (2021) (15)
- Association between abnormal nocturnal blood pressure profile and dementia in Parkinson's disease. (2018) (15)
- Genetic Mutations and Mitochondrial Toxins Shed New Light on the Pathogenesis of Parkinson's Disease (2011) (15)
- Occipital lobe seizures and subcortical T2 and T2* hypointensity associated with nonketotic hyperglycemia: a case report (2016) (15)
- Depressive symptoms in Parkinson’s disease are related to decreased left hippocampal volume: correlation with the 15-item shortened version of the Geriatric Depression Scale (2018) (15)
- Effects of Aging and Idiopathic Parkinson’s Disease on Tactile Temporal Order Judgment (2015) (15)
- Large aortic arch plaques correlate with CHADS2 and CHA2DS2-VASc scores in cryptogenic stroke. (2019) (15)
- EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population. (2014) (15)
- Analysis of eighteen deletion breakpoints in the parkin gene. (2009) (15)
- Parkinson’s disease: deep learning with a parameter-weighted structural connectome matrix for diagnosis and neural circuit disorder investigation (2021) (15)
- An 88-year-old woman with acute disseminated encephalomyelitis following messenger ribonucleic acid-based COVID-19 vaccination (2021) (15)
- Efficacy and Safety of a Once-daily Extended-release Formulation of Pramipexole Switched from an Immediate-release Formulation in Patients with Advanced Parkinson’s Disease: Results from an Open-label Study (2013) (15)
- Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker? (2019) (15)
- Brain White-Matter Degeneration Due to Aging and Parkinson Disease as Revealed by Double Diffusion Encoding (2020) (15)
- Postural Abnormality in Parkinson's Disease: A Large Comparative Study With General Population (2019) (14)
- Alterations of the optic pathway between unilateral and bilateral optic nerve damage in multiple sclerosis as revealed by the combined use of advanced diffusion kurtosis imaging and visual evoked potentials. (2017) (14)
- A novel mutation of CHCHD2 p.R8H in a sporadic case of Parkinson's disease. (2017) (14)
- Altered humoral immunity to mycobacterial antigens in Japanese patients affected by inflammatory demyelinating diseases of the central nervous system (2017) (14)
- The evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease (2014) (14)
- Neuromelanin or DaT‐SPECT: which is the better marker for discriminating advanced Parkinson's disease? (2019) (14)
- Anti-aquaporin-4 Antibody-positive Definite Neuromyelitis Optica in a Patient With Thymectomy for Myasthenia Gravis (2012) (14)
- Adult‐onset Alexander disease with palatal myoclonus and intraventricular tumour (2008) (14)
- Anti-NMDA receptor encephalitis due to large-cell neuroendocrine carcinoma of the uterus (2017) (14)
- A Randomized Controlled Trial of Subcutaneous Apomorphine for Parkinson Disease: A Repeat Dose and Pharmacokinetic Study (2015) (14)
- Lack of Genetic Association of the UCHL1 Gene with Alzheimer’s Disease and Parkinson’s Disease with Dementia (2012) (14)
- Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease (2019) (13)
- Subsecond reward-related dopamine release in the mouse dorsal striatum (2009) (13)
- Clinical and genetic studies on familial parkinsonism: The first report on a parkin gene mutation in a Taiwanese family (2001) (13)
- Reversible focal cerebral cortical lesions in a patient with heat stroke. (2013) (13)
- Adrenomedullin Deficiency and Aging Exacerbate Ischemic White Matter Injury after Prolonged Cerebral Hypoperfusion in Mice (2014) (13)
- Decreased Expression of hsa-miR-4274 in Cerebrospinal Fluid of Normal Pressure Hydrocephalus Mimics with Parkinsonian Syndromes (2016) (13)
- Can parkin be a target for future treatment of Parkinson's disease? (2013) (13)
- Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations (2019) (13)
- [Inherited peripheral neuropathy]. (2001) (13)
- Acute psychosis as an initial manifestation of hypothyroidism: a case report (2015) (13)
- Clinical characterization of patients with leucine-rich repeat kinase 2 genetic variants in Japan (2020) (13)
- Diagnostic Utility of Splenial Lesions in a Case of Legionnaires' Disease due to Legionella pneumophila Serogroup 2. (2015) (13)
- Mutation analysis for DJ-1 in sporadic and familial parkinsonism: Screening strategy in parkinsonism (2009) (13)
- Lysosomal defects in ATP13A2 and GBA associated familial Parkinson’s disease (2017) (13)
- Multiple sclerosis: Benefits of q-space imaging in evaluation of normal-appearing and periplaque white matter. (2014) (13)
- Induction and selective accumulation of mutant ubiquitin in CA1 pyramidal neurons after transient global ischemia (2007) (13)
- A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers (2020) (13)
- A new mutation in the GCH1 gene presents as early-onset Parkinsonism. (2009) (13)
- Genotype–phenotype correlations of cysteine replacement in CADASIL (2017) (13)
- Registry of Japanese patients with atrial fibrillation focused on anticoagulant therapy in the new era: The RAFFINE registry study design and baseline characteristics. (2018) (13)
- Rat mitochondrial mtDNA-binding proteins to inter-specifically conserved sequences in the displacement loop region of vertebrate mtDNAs. (1995) (12)
- Large-Scale RNA Interference Screening in Mammalian Cells Identifies Novel Regulators of Mutant Huntingtin Aggregation (2014) (12)
- Neuroimaging evaluation and successful treatment by using directional deep brain stimulation and levodopa in a patient with GNAO1-associated movement disorder: A case report (2020) (12)
- Sustained efficacy of apomorphine in Japanese patients with advanced Parkinson's disease. (2014) (12)
- Phosphorylated IκBα is a component of Lewy body of Parkinson’s disease (2005) (12)
- Mitochondrial-Associated Membranes in Parkinson's Disease. (2017) (12)
- Involvement of the Septo-Hippocampal Cholinergic Pathway in Association with Septal Acetylcholinesterase Upregulation in a Mouse Model of Tauopathy. (2016) (12)
- Dopaminergic Neuron-Specific Autophagy-Deficient Mice. (2018) (12)
- Rapid screening of ATP13A2 variant with high‐resolution melting analysis (2010) (12)
- Mutation screening of PLA2G6 in Japanese patients with early onset dystonia-parkinsonism (2017) (12)
- Ethambutol neutralizes lysosomes and causes lysosomal zinc accumulation. (2016) (12)
- Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification (2007) (12)
- Efficacy of Istradefylline, an Adenosine A2A Receptor Antagonist, as Adjunctive Therapy to Levodopa in Parkinson’s Disease: A Pooled Analysis of 8 Phase 2b/3 Trials (2021) (12)
- p150glued deficiency impairs effective fusion between autophagosomes and lysosomes due to their redistribution to the cell periphery (2019) (12)
- Marchiafava-Bignami disease mimics motor neuron disease: case report (2013) (12)
- Nuclear localization of the 20S proteasome subunit in Parkinson's disease (2006) (12)
- p150glued-Associated Disorders Are Caused by Activation of Intrinsic Apoptotic Pathway (2014) (12)
- CSF1R Mutation p.G589R and the Distribution Pattern of Brain Calcification (2017) (12)
- Accelerated Isotropic Multiparametric Imaging by High Spatial Resolution 3D-QALAS With Compressed Sensing (2020) (12)
- Lipid rafts involvement in the pathogenesis of Parkinson's disease. (2015) (12)
- Bilateral facial nerve palsy due to otitis media associated with myeloperoxidase-antineutrophil cytoplasmic antibody. (2013) (12)
- Metabolomic analysis revealed mitochondrial dysfunction and aberrant choline metabolism in MPP+-exposed SH-SY5Y cells. (2019) (12)
- Dopamine deficiency may lead to capgras syndrome in Parkinson's disease with dementia. (2010) (12)
- Possible involvement of iron-induced oxidative insults in neurodegeneration (2015) (12)
- Omega-3 Polyunsaturated Fatty Acids and Stroke Burden (2019) (12)
- Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia (2013) (12)
- Comprehensive mutational analysis of LRRK2 reveals variants supporting association with autosomal dominant Parkinson's disease (2011) (12)
- Spontaneous spinal subarachnoid hemorrhage after severe coughing: a case report (2013) (12)
- Rationale and design of the carotid plaque in human for all evaluations with aggressive rosuvastatin therapy (CHALLENGER trial): evaluation by magnetic resonance imaging. (2009) (12)
- Peripheral arterial atherosclerosis in patients with extracranial, not intracranial, arterial stenosis. (2010) (11)
- The identified clinical features of Parkinson's disease in homo-, heterozygous and digenic variants of PINK1 (2020) (11)
- Cerebral microbleeds and blood pressure abnormalities in Parkinson's disease (2017) (11)
- Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations. (1999) (11)
- Geographic and ethnic differences in frequencies of two polymorphisms (D/N394 and L/I272) of the parkin gene in sporadic Parkinson's disease. (2005) (11)
- Adjunctive preladenant: A placebo-controlled, dose-finding study in Japanese patients with Parkinson's disease. (2016) (11)
- The presence of cerebral microbleeds is associated with cognitive impairment in Parkinson's disease (2018) (11)
- Neuropathology of PARK14 is identical to idiopathic Parkinson's disease (2017) (11)
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- Analysis of the Usefulness of the WORSEN Score for Predicting the Deterioration of Acute Ischemic Stroke. (2017) (11)
- Efficacy and safety of adjunctive rasagiline in Japanese Parkinson's disease patients with wearing-off phenomena: A phase 2/3, randomized, double-blind, placebo-controlled, multicenter study. (2018) (11)
- Analysis of gene mutations in four cases of dermatofibrosarcoma protuberans (2006) (11)
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- Convulsive Movements in Bilateral Paramedian Thalamic and Midbrain Infarction (2011) (11)
- Utility of the Japanese version of the 9-item Wearing-off Questionnaire (2015) (11)
- Pleiotropic Effects of Exosomes as a Therapy for Stroke Recovery (2020) (11)
- Serum uric acid concentration is linked to wearing-off fluctuation in Japanese Parkinson's disease patients. (2014) (11)
- Subthalamic Deep Brain Stimulation for a Parkinson's Disease Patient With Duplication of SNCA (2014) (11)
- Neurocognitive and psychiatric disorders‐related axonal degeneration in Parkinson's disease (2020) (11)
- A family with hereditary diffuse leukoencephalopathy with spheroids caused by a novel c.2442+2T>C mutation in the CSF1R gene (2016) (11)
- Juvenile-onset parkinsonism with digenic parkin and PINK1 mutations treated with subthalamic nucleus stimulation at 45years after disease onset (2014) (11)
- COQ2 variants in Parkinson’s disease and multiple system atrophy (2018) (10)
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- Molecular genetics of Parkinson’s disease: Contributions and global trends (2022) (10)
- Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism (2019) (10)
- Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation (2022) (10)
- Specific mechanisms of subarachnoid hemorrhage accompanied by ischemic stroke in essential thrombocythemia: two case reports and a literature review (2019) (10)
- Differences in phosphodiesterase 3A and 3B expression after ischemic insult (2013) (10)
- Isolated reversible splenial lesion in adult meningitis: a case report and review of the literature. (2007) (10)
- Vertebral artery dissection in patients with autosomal dominant polycystic kidney disease. (2014) (10)
- Low cardiac 123I-MIBG uptake in late-onset familial amyloid polyneuropathy type I (TTR Met30) (2001) (10)
- Mutation analysis of LRP10 in Japanese patients with familial Parkinson's disease, progressive supranuclear palsy, and frontotemporal dementia (2019) (10)
- Long-term safety and efficacy of safinamide as add-on therapy in levodopa-treated Japanese patients with Parkinson's disease with wearing-off: Results of an open-label study (2020) (10)
- The absence of orthostatic heart rate increase is associated with cognitive impairment in Parkinson’s disease (2020) (10)
- Adjuvant and antigenic properties of Mycobacterium avium subsp. paratuberculosis on experimental autoimmune encephalomyelitis (2019) (10)
- Analysis of normal-appearing white matter of multiple sclerosis by tensor-based two-compartment model of water diffusion (2015) (10)
- Schizophrenia as a prodromal symptom in a patient harboring SNCA duplication. (2016) (10)
- Impact of low-density lipoprotein to high-density lipoprotein ratio on aortic arch atherosclerosis in unexplained stroke (2013) (10)
- Serial MRI alterations of pediatric patients with beta-propeller protein associated neurodegeneration (BPAN). (2020) (10)
- Daytime symptoms of restless legs syndrome--clinical characteristics and rotigotine effectiveness. (2015) (9)
- Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS (2016) (9)
- Good’s syndrome with opportunistic infection of the central nervous system: a case report (2015) (9)
- Posterior Subthalamic Area Deep Brain Stimulation for Fragile X–Associated Tremor/Ataxia Syndrome (2014) (9)
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex (2019) (9)
- Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study (2021) (9)
- Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease. (2021) (9)
- Cerebral dural sinus thrombosis associated with adenomyosis: a case report. (2014) (9)
- Gradient echo T2*-weighted magnetic resonance imaging revealing cerebral microbleeds in a patient with microscopic polyangiitis complicated by cerebrovascular disease. (2012) (9)
- PLA2G6 variants associated with the number of affected alleles in Parkinson’s disease in Japan (2020) (9)
- Autosomal dominant parkinsonism: its etiologies and differential diagnoses. (2012) (9)
- Successful immune moderation treatment for progressive encephalomyelitis with rigidity and myoclonus. (2015) (9)
- Characteristics of Clinical Symptoms, Cerebral Images and Stroke Etiology in Vertebro-Basilar Artery Fenestration-Related Infarction (2020) (9)
- Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury (2022) (9)
- Mutation Analysis of the PINK 1 Gene in 391 Patients With Parkinson Disease (2008) (9)
- Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease. (2019) (9)
- Longitudinally Extensive Transverse Myelitis with Intramedullary Metastasis of Small-Cell Lung Carcinoma: An Autopsy Case Report (2013) (9)
- Appropriate dosing of pergolide in monotherapy and adjunctive therapy in Parkinson's disease (2003) (9)
- Clinical manifestations of Parkinson's disease harboring VPS35 retromer complex component p.D620N with long-term follow-up. (2021) (9)
- Deep cerebral venous thrombosis mimicking influenza-associated acute necrotizing encephalopathy: a case report (2017) (9)
- Phosphorylated recombinant HSP27 protects the brain and attenuates blood-brain barrier disruption following stroke in mice receiving intravenous tissue-plasminogen activator (2018) (9)
- Network Centrality Reveals Dissociable Brain Activity during Response Inhibition in Human Right Ventral Part of Inferior Frontal Cortex (2020) (9)
- A Pooled Analysis From Phase 2b and 3 Studies in Japan of Istradefylline in Parkinson's Disease (2020) (9)
- Wireless voltammetry recording in unanesthetised behaving rats (2008) (9)
- Asparagine residue 368 is involved in Alzheimer's disease tau strain–specific aggregation (2020) (9)
- Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. (2022) (8)
- Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning (2021) (8)
- Toshiharu (Toshi) Nagatsu: an appreciation (2017) (8)
- Evaluation of nocturnal hypokinesia in Parkinson's disease using a novel patient/proxy questionnaire and correlations with objective monitoring. (2019) (8)
- Fibromyalgia syndrome and cognitive dysfunction in elderly: a case series (2016) (8)
- Genetic and functional analysis of KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis (2020) (8)
- Analysis of-Synuclein Gene Promoter Variability and Parkinson Disease (2006) (8)
- Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins. (2006) (8)
- Mucosal‐Associated Invariant T Cells Are Involved in Acute Ischemic Stroke by Regulating Neuroinflammation (2021) (8)
- High-fat diet–induced activation of SGK1 promotes Alzheimer’s disease–associated tau pathology (2021) (8)
- Immunotoxin Screening System: A Rapid and Direct Approach to Obtain Functional Antibodies with Internalization Capacities (2020) (8)
- Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice. (2021) (8)
- Case Report: Chronic Adaptive Deep Brain Stimulation Personalizing Therapy Based on Parkinsonian State (2021) (8)
- Phosphorylated IkappaBalpha is a component of Lewy body of Parkinson's disease. (2005) (8)
- The Direct Cost of Parkinson Disease at Juntendo Medical University Hospital, Japan. (2016) (8)
- Pharmacokinetics and effect of food after oral administration of prolonged‐release tablets of ropinirole hydrochloride in Japanese patients with Parkinson’s disease (2012) (8)
- 3D Quantitative Synthetic MRI in the Evaluation of Multiple Sclerosis Lesions (2021) (8)
- Genetic analysis of TMEM230 in Japanese patients with familial Parkinson's disease. (2017) (8)
- Phenotype of the 202 adenine deletion in the parkin gene: 40 years of follow‐up (2011) (8)
- Anterior opercular syndrome induced by Epstein–Barr virus encephalitis (2016) (8)
- Pontine hemorrhage accompanied by neuromyelitis optica spectrum disorder (2019) (8)
- The commercial genetic testing landscape for Parkinson's disease. (2021) (8)
- Immunocytochemical Monitoring of PINK1/Parkin-Mediated Mitophagy in Cultured Cells. (2018) (8)
- Cerebral small artery diseases may be associated with aortic arch calcification in stroke patients. (2014) (8)
- Effects of donepezil dose escalation in Parkinson's patients with dementia receiving long‐term donepezil treatment: an exploratory study (2014) (8)
- Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease (2019) (8)
- Balance and Gait Improvements of Postoperative Rehabilitation in Patients with Parkinson's Disease Treated with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) (2019) (8)
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- Parallel cognitive processing streams in human prefrontal cortex: Parsing areal-level brain network for response inhibition. (2021) (7)
- Lymphomatoid Granulomatosis with Central Nervous System Involvement Successfully Treated with Cyclophosphamide, High‐dose Cytarabine, Dexamethasone, Etoposide, and Rituximab (CHASER therapy) Followed by Brain Irradiation: A Case Study (2015) (7)
- Recurrent embolic strokes associated with vertical atlantoaxial subluxation in a patient with rheumatoid arthritis: a case report and review of literature. (2013) (7)
- FACS-array–based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model (2020) (7)
- A Patient with the GLA p.E66Q Mutation Exhibiting Vascular Parkinsonism and Bilateral Pulvinar Lesions. (2015) (7)
- Association of Orthostatic Hypotension With Cerebral Atrophy in Patients With Lewy Body Disorders (2021) (7)
- Eicosapentaenoic-to-Arachidonic Acid Ratio Predicts Mortality and Recurrent Vascular Events in Ischemic Stroke Patients (2020) (7)
- Visual grasping in frontotemporal dementia and parkinsonism linked to chromosome 17 (microtubule‐associated with protein tau): A comparison of N‐Isopropyl‐p‐[123I]‐iodoamphetamine brain perfusion single photon emission computed tomography analysis with progressive supranuclear palsy (2011) (7)
- Real‐World Nonmotor Changes in Patients with Parkinson's Disease and Motor Fluctuations: J‐FIRST (2020) (7)
- Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome (2017) (7)
- Correction: Gut dysbiosis is associated with metabolism and systemic inflammation in patients with ischemic stroke (2017) (7)
- Specific detection of deleted mitochondrial DNA by in situ hybridization using a chimera probe. (1996) (7)
- Shared Metabolic Profile of Caffeine in Parkinsonian Disorders (2020) (7)
- Genetic spectrum of Charcot–Marie–Tooth disease associated with myelin protein zero gene variants in Japan (2020) (7)
- Associations between probable REM sleep behavior disorder, olfactory disturbance, and clinical symptoms in Parkinson’s disease: A multicenter cross-sectional study (2021) (7)
- High prevalence of anti‐TSH receptor antibody in fibromyalgia syndrome (2017) (7)
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- Heterozygous HTRA1 mutations with mimicking symptoms of CARASIL in two families (2018) (7)
- 122nd annual meeting american neurological association (1997) (7)
- A novel immunotoxin reveals a new role for CD321 in endothelial cells (2017) (7)
- Subthalamic nucleus and globus pallidus interna influence firing of tonically active neurons in the primate striatum through different mechanisms (2017) (7)
- No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients (2010) (7)
- Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case–control study (2017) (7)
- Widespread enlarged perivascular spaces associated with dementia and focal brain dysfunction: case report (2017) (7)
- Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration. (2022) (7)
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- Underlying embolic and pathologic differentiation by cerebral microbleeds in cryptogenic stroke (2020) (6)
- Multi-year whole-blood transcriptome data for the study of onset and progression of Parkinson’s Disease (2019) (6)
- Motor-dominant polyneuropathy due to IgM monoclonal antibody against disialosyl gangliosides in a patient with mantle cell lymphoma (2014) (6)
- Autosomal Recessive Juvenile Parkinsonism (AR-JP): Genetic Diagnosis. (2001) (6)
- Movement disorders: advances in 2015 (2016) (6)
- Dual use of rectangular and triangular waveforms in voltammetry using a carbon fiber microelectrode to differentiate norepinephrine from dopamine (2017) (6)
- Dopamine transporter imaging predicts motor responsiveness to levodopa challenge in patients with Parkinson's disease: A pilot study of DATSCAN for subthalamic deep brain stimulation (2018) (6)
- Holomedicine: Proof of the Concept of Interactive Three‐Dimensional Telemedicine (2020) (6)
- Atypical Miller Fisher syndrome associated with glutamate receptor antibodies (2011) (6)
- Intrajejunal Infusion of Levodopa/Carbidopa for Advanced Parkinson's Disease: A Systematic Review (2021) (6)
- CHCHD2 and Parkinson's disease—Authors' reply (2015) (6)
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- A large Japanese family with Machado–Joseph disease: clinical and genetic analysis (1999) (6)
- White matter lesions and cognitive impairment may be related to recovery from unilateral spatial neglect after stroke (2017) (6)
- Mutation of the Parkin gene in a Persian family: Clinical progression over a 40‐year period (2005) (6)
- Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy (2019) (6)
- The prevalence, course and clinical correlates of migraine in Parkinson’s disease: A multicentre case-controlled study (2018) (6)
- Demyelinating Peripheral Neuropathy Due to Renal Cell Carcinoma (2017) (6)
- Isolated proximal leg paresis due to a small cortical infarction. (2010) (6)
- White matter alterations in Parkinson's disease with levodopa-induced dyskinesia. (2021) (6)
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- [Pathogenesis of Parkinson's disease: a common pathway between alpha-synuclein and parkin and the mechanism of Lewy bodies formation]. (2005) (6)
- Vivid visual hallucinations manifested as the initial symptom in a patient with neurosyphilis. (2013) (6)
- Microstructural white matter abnormalities in multiple sclerosis and neuromyelitis optica spectrum disorders: Evaluation by advanced diffusion imaging (2022) (6)
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- Galantamine Response Associates with Agitation and the Prefrontal Cortex in Patients with Alzheimer's Disease. (2017) (5)
- Impact of BNP on cryptogenic stroke without potential embolic sources on transesophageal echocardiography (2015) (5)
- Retroperitoneal fibrosis secondary to pergolide therapy. (2010) (5)
- Multiple cerebral infarction diagnosed as Eosinophilic Granulomatosis with Polyangiitis by autopsy (2019) (5)
- Dopamine agonist withdrawal syndrome in a patient with restless legs syndrome without impulse control disorder or drug abuse (2015) (5)
- High-fat diet-induced activation of SGK1 promotes Alzheimer’s disease-associated tau pathology (2020) (5)
- Evaluation of white matter microstructure in patients with Parkinson’s disease using microscopic fractional anisotropy (2019) (5)
- Pseudo‐heterozygous rearrangement mutation of parkin (2012) (5)
- Rescue Levodopa/Carbidopa Intestinal Gel for Secondary Deep Brain Stimulation Failure (2020) (5)
- Long-term safety and efficacy of opicapone in Japanese Parkinson’s patients with motor fluctuations (2021) (5)
- New modalities and directions for dystonia care (2021) (5)
- Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons (2021) (5)
- Pre-existing Mobile Cardiac Thrombus and the Risk of Early Recurrent Embolism after Intravenous Thrombolysis: A Case Report. (2015) (5)
- Transdermal rotigotine patch in Parkinson’s disease with a history of intestinal operation (2018) (5)
- Cerebral infarction in a case of Parry-Romberg syndrome. (2014) (5)
- Differentiation between multiple sclerosis and neuromyelitis optica spectrum disorders by multiparametric quantitative MRI using convolutional neural network (2021) (5)
- Glycyl-alanyl-histidine protects PC12 cells against hydrogen peroxide toxicity (2017) (5)
- Effect of subthalamic nucleus deep brain stimulation on visual scanning (2018) (5)
- Dopamine induces supernumerary centrosomes and subsequent cell death through Cdk2 up-regulation in dopaminergic neuronal cells (2008) (5)
- Parkinson Disease-Linked Parkin Mediates Redox Reactions That Lower Oxidative Stress In Mammalian Brain (2020) (5)
- Determinants of Low Body Mass Index in Patients with Parkinson's Disease: A Multicenter Case-Control Study. (2019) (5)
- Pharmacokinetic Comparison of Capsule and Tablet Formulations of Opicapone in Healthy Japanese Subjects: Phase 1 Study (2020) (5)
- A mucosal immune response induced by oral administration of heat-killed Mycobacterium avium subsp. paratuberculosis exacerbates EAE (2021) (5)
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- Teaching Video NeuroImages: Re-emergent jaw tremor in Parkinson disease (2015) (5)
- Preserved cardiac 123I‐MIBG uptake and lack of severe autonomic dysfunction in a PARK9 patient (2009) (5)
- Zonisamide Administration Improves Fatty Acid β-Oxidation in Parkinson’s Disease (2018) (5)
- Ropinirole Patch Versus Placebo, Ropinirole Extended‐Release Tablet in Advanced Parkinson's Disease (2020) (5)
- Freezing of gait in Parkinson’s disease may share the mechanisms of dystonia (2019) (5)
- Clinical Characterization of Definite Autoimmune Limbic Encephalitis: A 30-case Series (2019) (5)
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- Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study (2021) (4)
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- Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study (2022) (4)
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- Dystonia due to bilateral caudate hemorrhage associated with a COL4A1 mutation. (2017) (4)
- Multiple sclerosis plaques may undergo continuous myelin degradation: a cross-sectional study with myelin and axon-related quantitative magnetic resonance imaging metrics (2021) (4)
- Long-term safety and efficacy of adjunctive rasagiline in levodopa-treated Japanese patients with Parkinson’s disease (2019) (4)
- Lateral and Dorsal Column Hyperintensity on Magnetic Resonance Imaging in a Patient with Myelopathy Associated with Intrathecal Chemotherapy (2013) (4)
- Autosomal recessive juvenile Parkinson's disease with partial Trisomy of chromosome 6q syndrome: A case report (2004) (4)
- Eosinophilic meningitis caused by primary angiitis of the central nervous system. (2013) (4)
- Mitochondrial abnormalities in Parkinson's disease (1992) (4)
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- Fatal ischemic stroke caused by cerebral small arteritis in a patient with giant cell arteritis (2018) (4)
- Cerebrospinal fluid dissemination of anaplastic intraventricular meningioma: report of a case presenting with progressive brainstem dysfunction and multiple cranial nerve palsies (2016) (4)
- Cerebral infarction in an HIV-infected patient with combined protein S and C deficiency and a patent foramen ovale. (2013) (4)
- Dermatomal sensory manifestations in lateral medullary infarction. (2014) (4)
- Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus (2021) (4)
- Serum uric acid level is linked to the disease progression rate in male patients with multiple system atrophy (2017) (4)
- A Novel LRRK2 Variant p.G2294R in the WD40 Domain Identified in Familial Parkinson’s Disease Affects LRRK2 Protein Levels (2021) (4)
- Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation (2005) (4)
- Marked Reduction in the Striatal Dopamine Transporter Uptake During the Early Stage of Motor Symptoms in Patients with the MAPT N279K Mutation (2018) (4)
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- CV2/CRMP5-antibody-related Paraneoplastic Neurologic Syndrome Associated with Gastrointestinal Stromal Tumor (2021) (0)
- Diamond microelectrodes for dopamine detection in the brain (2007) (0)
- Analysis of Pael-R complex components as Parkin substrates (2009) (0)
- Clinically isolated syndrome in collagen diseases; approaches and treatments (2012) (0)
- Parkinson's disease-associated genes regulate the quality control of α-synuclein at presynapses through the endo-lysosomal pathway (2019) (0)
- Association of blood eicosapentaenoic acid levels with intracerebral hemorrhage during the COVID-19 pandemic: preliminary experience from a single-center in Japan (2022) (0)
- Parkinson's desease related protein VPS13C involved in autophagy (2019) (0)
- Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers (2023) (0)
- Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson's disease (vol 4, pg 195, 2002) (2002) (0)
- Extremely low-frequency pulses of faint magnetic field, weaker than the geomagnetic field, induce mitophagy to rejuvenate mitochondria (2021) (0)
- Generation of three hiPSC clones from a Parkinson's disease patient with a heterozygous variant of VPS35 p.D620N. (2022) (0)
- P2.089 Efflcacy of pramipexole extended release (ER) and switching from pramipexole immediate release (IR) to ER in Japanese advanced PD patients (2009) (0)
- Interview with Nobutaka Hattori: a life researching Parkinson's disease pathogenesis. (2023) (0)
- Effect of baseline dyskinesia on safety and efficacy of istradefylline, an A2A receptor antagonist, in Parkinson's disease: 8-study pooled analysis (2020) (0)
- PM Association Between Silent Lacunar Infarcts And Muscle Strength: The Bunkyo Health Study (2020) (0)
- A Case of New-onset Refractory Status Epilepticus Involving the Limbic System, Spinal Cord, and Peripheral Nerves (2019) (0)
- [Parkinson's disease and it's look-alike]. (2020) (0)
- Female, Aging, Low ratio of DCI or lower body weight increases AUC4hr of levodopa in patients with Parkinson's disease (2020) (0)
- Cerebrovascular diseases in two patients with entire NSD1 deletion (2021) (0)
- Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice (2020) (0)
- III. Widespread Pain Evoked by Neurological Disorders (2019) (0)
- Abstract P349: Neuroprotective Effects of L-Carnitine on Vascular Dementia in Hemodialysis Patients (2021) (0)
- Temporal Profile of CT and T2*-Weighted Gradient-Echo MRI in a Patient with Unilateral Thalamostriate Vein Thrombosis. (2019) (0)
- [A 54-year-old man with familial parkinsonism, gaze palsy, and dementia]. (2005) (0)
- [The gene products for familial Parkinson's disease provide us hints to elucidate the mechanisms of nigral degeneration]. (2004) (0)
- [Therapy of peripheral nerve disturbances--current progress]. (1999) (0)
- Yokukansan Ameliorates Psychiatric Problems in Parkinson's Disease (Update on Yokukansan) (2014) (0)
- Collective Expert Perspectives on the Use of Safinamide as Adjunctive Therapy for Parkinson's Disease: Online-Based Delphi Survey (2022) (0)
- Abstract T MP97: Efficacy of Poststroke Intensive Rosuvastatin Treatment for Aortogenic Embolic Stroke: Episteme Trial (2014) (0)
- [Perspective of α-synuclein and Familial Parkinson's Disease]. (2020) (0)
- Peking University - Juntendo University Joint Symposium on Brain and Skin Diseases Genetics and Parkinson's Disease (2016) (0)
- Neurogenetics in Parkinson's Disease (2008) (0)
- [Juvenile parkinsonism]. (2003) (0)
- P2-161: Behavioral abnormality in female mice expressing wild-type human tau without neurofibrillary tangles (2008) (0)
- The PD causative gene Vps35 cooperates with genes involved in the synaptic vesicle regeneration to regulate neural activity (2017) (0)
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue (2012) (0)
- Author Correction: Altered humoral immunity to mycobacterial antigens in Japanese patients affected by inflammatory demyelinating diseases of the central nervous system (2020) (0)
- Risk factors for developing dyskinesia among Parkinson's disease patients with wearing-off: J-FIRST (2023) (0)
- Synaptic vesicle dynamics are regulated by a subset of Parkinson’s disease genes (2016) (0)
- Substantia nigra analysis by tensor decomposition of T2-weighted images for Parkinson’s disease diagnosis (2022) (0)
- Reply to CLIPPERS features before, during and after lymphoma (2016) (0)
- Optogenetic Neuromodulation (S52.007) (2015) (0)
- The role of perlecan in nnos mediated mechanotransduction in skeletal muscle (2017) (0)
- iPSC-based Drug Screening for PARK9, a Familial Parkinson’s Disease with Impaired Autophagy (2021) (0)
- [Molecular biology for familial Parkinson's disease]. (2004) (0)
- Abstract WP339: Modulation of Gut Microbiota Improves Outcomes After Ischemic Stroke by Reducing Lipopolysaccharide-Induced Inflammation in the Ischemic Brain of Diabetic Mice (2019) (0)
- Abstract WP148: The Effect of Mitochondrial Migration From Astrocyte to Glial Cells Under Prolonged Cerebral Hypoperfusion (2020) (0)
- [Neuromuscular disorders due to adverse effects of antiparkinson agents]. (2007) (0)
- Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure (2020) (0)
- Effects of rasagiline on Parkinson’s Disease Questionnaire (PDQ-39) emotional well-being domain in patients with Parkinson’s disease: A post-hoc analysis of clinical trials in Japan (2022) (0)
- Standard strategies for diagnosis and treatment of patients with newly diagnosed Parkinson disease: JAPAN. (2013) (0)
- Author Correction: Altered humoral immunity to mycobacterial antigens in Japanese patients affected by inflammatory demyelinating diseases of the central nervous system (2020) (0)
- Delayed-onset motor aphasia succeeds Holmes' tremor and neuropathic pain after left thalamic hemorrhage (2021) (0)
- Selected abstracts from the 21st International Congress (2017) (0)
- [Deep Brain Stimulation for Parkinson Disease:Mechanisms and New Technology]. (2017) (0)
- Bacillus Calmette-Guérin Tokyo-172 vaccine provides age-related neuroprotection in actively induced and spontaneous experimental autoimmune encephalomyelitis models. (2023) (0)
- [Internal medicine and neurological diseases: progress in diagnosis and treatment topics: X. Neurological disorders in connective tissue disease]. (2012) (0)
- Abstract W P122: Cerebral Small Vessel Diseases May be Associated With Aortic Arch Calcification in Patients With Acute Stroke (2014) (0)
- [A 65-year-old woman with progressive loss of vision and visual field defects]. (2003) (0)
- Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease (2017) (0)
- BLT 2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression (2017) (0)
- [Management of Spinal Disorders in Parkinson's Disease]. (2021) (0)
- Delayed chorea after recovery from severe akinetic-rigid parkinsonism caused by extrapontine myelinolysis (2015) (0)
- X. Neurological Disorders in Connective Tissue Disease (2012) (0)
- Short-Term Motor Outcomes in Parkinson's Disease after Subthalamic Nucleus Deep Brain Stimulation Combined with Post-Operative Rehabilitation: A Pre-Post Comparison Study (2022) (0)
- Mitochondrial dysfucntion in Parkinson's disease (2007) (0)
- Loss of ghrelin receptors in dopaminergic neurons in the substantia nigra is critical for Parkinson's disease-like motor dysfunction (2018) (0)
- Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals. (2023) (0)
- [Malignant migraine]. (2002) (0)
- Levodopa Therapy for the Treatment of Parkinson’s Disease (2020) (0)
- Restless legs syndrome and leg motor restlessness in patients with Parkinson's disease: a multicenter case-controlled study (2017) (0)
- A case with difficulty in the diagnose of cardiogenic or aortogenic brain embolism (2015) (0)
- Analysis of a new molecule that is involved in the PINK1-Parkin signaling. (2017) (0)
- Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice (2022) (0)
- Levodopa/Carbidopa Intestinal Gel in Parkinson’s Disease (2020) (0)
- Astrocytic 3-Repeat Tau Pathologies in Progressive Supranuclear Palsy. (2020) (0)
- A case of chronic progressive external ophthalmoplegia presenting with central neurogenic hyperventilation (2022) (0)
- Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion Coincidents with Bickerstaff Brainstem Encephalitis. (2022) (0)
- Hypothalamic interaction with reward-related regions during subjective evaluation of foods (2022) (0)
- Alpha-synuclein and familial Parkinson's disease (2018) (0)
- Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson’s disease (2022) (0)
- The effect of impaired biogenesis and release of exosomes on the alpha synuclein accumulation in Kufor-Rakeb syndrome (2016) (0)
- Long term follow-up of Segawa disease White matter integrity in the tegmentum area correlates with freezing of gait (2015) (0)
- Region-Specific Vulnerability of Neuroinflammation, Oxidative Stress and Tau Hyperphosphorylation in Experimental Diabetes (2016) (0)
- Systemic Sclerosis Precedes POEMS Syndrome (2020) (0)
- T36. Motor axonal abnormalities in anti-MAG neuropathy (2018) (0)
- [Subacute idiopathic demyelinating polyradiculoneuropathy (SIDP)]. (1999) (0)
- Correction: Long-term effects of safinamide adjunct therapy on levodopa-induced dyskinesia in Parkinson’s disease: post-hoc analysis of a Japanese phase III study (2022) (0)
- Ubiquitin-Proteasome Pathway is a Key to Understanding of Nigral Degeneration in Autosomal Recessive Juvenile Parkinson’s Disease (2002) (0)
- Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson's disease [Parkinsonism Relat Disord 6 (4) (2000) 195–197] (2002) (0)
- Do stroke patients get to hospital in time for treatment? Results from national neurology registry (2017) (0)
- Regulation of membrane dynamics by Parkinson’s disease-associated genes (2018) (0)
- Dysregulated B cell differentiation towards antibody-secreting cells in neuromyelitis optica spectrum disorder (2022) (0)
- Significance of basic research from the clinical point of view (Neurology) (2019) (0)
- A Pooled Analysis for Eight Randomized Controlled Trials of Istradefylline, an Adenosine A2A Receptor Antagonist: Efficacy as Adjunct to Levodopa in Parkinson’s Disease (PD) (P3.8-030) (2019) (0)
- Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease (2022) (0)
- Truncated tau causes microtubule disassembly with aging in tauopathy model mice (2013) (0)
- Abnormal expression patterns of nociceptors in Parkinson's disease-specific iPSC-derived sensory neurons (2018) (0)
- Abnormal circadian blood pressure regulation and cognitive impairment in α-synucleinopathies (2022) (0)
- Deep Brain Stimulation for a Patient with Familial Parkinson's Disease Harboring CHCHD2 p.T61I (2022) (0)
- Electrical cortical stimulations modulate spike and post-spike slow-related high-frequency activities in human epileptic foci (2020) (0)
- Application of Light-driven proton transporter to treatment of CHCHD2 mutated Parkinson's disease (2017) (0)
- A High-Throughput Disease-Specific Phenotype Detection System of Parkinson’s Disease (2019) (0)
- Abstract 181: Large Aortic Arch Plaques are Associated With CHADS 2 and CHA 2 DS 2 -VASc Scores: A Multicenter Registry Analysis (2019) (0)
- Deep brain stimulation for Parkinson's disease. (2017) (0)
- Molecular Biology of α-Synuclein (2002) (0)
- Analysis of in (2021) (0)
- Establishment of a new mice model of Parkinson's disease exhibiting decreased locomotive activity (2010) (0)
- Mutant ubiquitin accumulate in CA1 pyramidal cells after transient global ischemia in gerbil (2005) (0)
- Continuous 24-h Levodopa-Carbidopa Intestinal Gel Infusion After a Levodopa Holiday Suppressed Refractory Dyskinesia Despite Increasing Levodopa Dose (2022) (0)
- T44. Abnormalities of motor axonal properties in amyotrophic lateral sclerosis (2018) (0)
- ' s response to reviews Title : Marchiafava-Bignami disease mimics motor neuron disease : Case Report (0)
- A Novel Heterozygous Missense Variant in the CIAO1 Gene in a Family with Alzheimer’s Disease: The Val67Ile Variant Promotes the Interaction of CIAO1 and Amyloid-β Protein Precursor (2021) (0)
- Mitophagy Controlled by the PINK1-Parkin Pathway Is Associated with Parkinson’s Disease Pathogenesis (2014) (0)
- [Pathogenesis and contribution of mitochondria to diabetes or deafness]. (2002) (0)
- Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion (2012) (0)
- [Molecular genetics of familial Parkinson's disease]. (2010) (0)
- P3.132 Alpha-synuclein in stem cells (2009) (0)
- Evaluating the Potential Pathology and Short-Term Outcomes of Cryptogenic Stroke Using the Etiological Classification System (2022) (0)
- A Narrative Review of Current Status and Future Perspective of Telemedicine for Parkinson's Disease, Dementia, and Intractable Neurological Diseases in Japan (2023) (0)
- Evaluation of Human-Induced Pluripotent Stem Cells Derived from a Patient with Schwartz–Jampel Syndrome Revealed Distinct Hyperexcitability in the Skeletal Muscles (2023) (0)
- IC-P1-033: Carbon 11-labeled Pittsburgh Compound B retention in the occipital cortex in posterior cortical atrophy (2008) (0)
- Parkin and Synuclein in Parkinson's Disease (2003) (0)
- UQCRC1 Engages Cytochrome C for Neuronal Apoptotic Cell Death (2020) (0)
- Abstract TMP72: L-carnitine Enhances Axonal Plasticity Via Akt/mammalian Target Of Rapamycin Pathway In A Rat Chronic Cerebral Hypoperfusion (2013) (0)
- The analyze of four pedigrees with MAPT N279K mutation accompanying DAT scan and Tau imaging (2015) (0)
- [Adult-onset case of idiopathic neurodegeneration with brain iron accumulation without mutations in the PANK2 and PLA2G6 genes]. (2009) (0)
- [Gene abnormalities in Parkinson disease]. (2005) (0)
- Radiation-Induced Myopathy Developing in a Hodgkin Lymphoma Patient: An Autopsy Case with Systemic Muscle Sampling (2021) (0)
- Fiber-specific white matter alterations in early-stage tremor-dominant Parkinson’s disease (2021) (0)
- FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis (2015) (0)
- Varicella-zoster virus encephalitis resembling herpes simplex virus encephalitis (2021) (0)
- Screening for Parkinson's disease-related genes that control vesicle trafficking and synaptic vesicle release (2016) (0)
- Re-emergent tremor in a patient with Parkinson's disease (2016) (0)
- 2K1545 Parkin binds the Rpn10 subunit of 26S proteasomes with the ubiquitin-like domain (2002) (0)
- Genetic screening of Filipinos suspected with familial Parkinson's disease: A pilot study. (2023) (0)
- Stroke in Patients With Common Noncancerous Gynecologic Diseases: A Multicenter Study in Japan. (2023) (0)
- Analysis of dopaminergic dysfunction-related molecules in the developmental stage of Parkinson’s disease using human disease-specific iPS cells (2017) (0)
- T-L-104 SAFETY AND EFFICACY OF LONG-TERM TREATMENT WITH ROTIGOTINE IN JAPANESE PATIENTS WITH RESTLESS LEGS SYNDROME (2011) (0)
- Perlecan, a heparan surfate proteoglycan, regulates metabolic dynamics (2017) (0)
- Impact of D-dimer for pathologic differentiation on transesophageal echocardiography in embolic stroke of undetermined source: a single-center experience (2022) (0)
- Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations (2018) (0)
- Two cases of steroid‐responsive encephalomyelitis with reversible diffuse cerebral arterial stenosis: A case report and review of the literature (2015) (0)
- Pattern Analysis of Substantia Nigra in Parkinson Disease by Fifth-Order Tensor Decomposition and Multi-sequence MRI (2022) (0)
- [A patient with focal bi-parietal atrophy presenting motor clumsiness and cortical sensory loss]. (1998) (0)
- Reversible Cerebral Vasoconstriction Syndrome Presenting as Cortical Subarachnoid Hemorrhage (2012) (0)
- Commentary: Progressive Encephalomyelitis with Rigidity and Myoclonus and Myasthenia Gravis Comorbid Status with Thymoma (2021) (0)
- The Pathogenesis of Parkinson disease (PD): A hint from gene products for Familial PD (2011) (0)
- Visual impairment as a possible precursor symptom of Marchiafava–Bignami disease (2013) (0)
- P256 Increased Barrett-Barrett conductance in motor axons of patients with anti-gad antibody (2017) (0)
- [Indication for Deep Brain Stimulation]. (2019) (0)
- Clinical hetrogeneity of gch1 mutations in parkinsonism with or without dystonia (2017) (0)
- Recurrent and Multiple Intracerebral Hemorrhages in Polycythemia Vera Secondary to Myelofibrosis: A Case Report and Literature Review (2022) (0)
- Clinicogenetic study of CHCHD2 in patients with autosomal dominant familial Parkinson's disease (2015) (0)
- Comparison of primary and secondary stroke prevention in patients with nonvalvular atrial fibrillation: Results from the RAFFINE registry. (2022) (0)
- [The pathomechanisms of young-onset Parkinson's disease (PD), approach to the causes of PD form the mechanisms of insulin secretion system]. (2011) (0)
- Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations (2019) (0)
- [A 73-year-old woman with depression, dementia, and parkinsonism]. (2005) (0)
- Neuronuclear and Neuromelanin‐Sensitive Imaging for Acquired Hepatocerebral Degeneration with Parkinsonism (2021) (0)
- RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY ON THE EFFICACY AND SAFETY OF GABAPENTIN ENACARBIL IN JAPANESE PATIENTS WITH PRIMARY RESTLESS LEGS SYNDROME (2011) (0)
- [Treatments for Parkinson's Disease -Essential Knowledge for General Physicians - Topics: II. Familial Parkinson's Disease Causative Genes Shed Light on the Molecular Pathogenesis]. (2015) (0)
- Role of the subthalamic nucleus in perceiving and estimating the passage of time (2023) (0)
- Application of current steering with MICC directional lead in STN-DBS for Parkinson’s disease (2023) (0)
- Assessment of iPS Cell-derived Dopaminergic Progenitor Cells Properties with Long-term Passaging and Amplification (2023) (0)
- Priority attention network with Bayesian learning for fully automatic segmentation of substantia nigra from neuromelanin MRI (2023) (0)
- Deep brain stimulation in posterior subthalamic area for Holmes tremor: Case reports with review of the literature (2023) (0)
- Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice (2018) (0)
- Gray Matter Alterations in Early and Late Relapsing-Remitting Multiple Sclerosis Evaluated with Synthetic Quantitative Magnetic Resonance Imaging (2019) (0)
- Successful engraftment of bladder organoids in de-epithelialized mouse colon (2022) (0)
- White matter and nigral alterations in multiple system atrophy-parkinsonian type (2021) (0)
- Analytical and clinical validity of wearable, multi-sensor technology for assessment of motor function in patients with Parkinson’s disease in Japan (2023) (0)
- Impaired virtual space-tilting perception in Parkinson's disease with Pisa syndrome. (2022) (0)
- Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
- Analysis of LIN28A variants in patients with Parkinson’s disease (2023) (0)
- Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle (2018) (0)
- [Acute motor neuropathy]. (1999) (0)
- Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of thalamus (2022) (0)
- Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations (2020) (0)
- “Super” high-frequency subthalamic stimulation for managing refractory dyskinesia in Parkinson’s disease (2022) (0)
- Pathophysiological analysis of Parkinson's disease using iPS cells. (2015) (0)
- Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation (2022) (0)
- POSA415 Association of an Adenosine A2A Antagonist Istradefylline on the Treatment Paradigm of Levodopa for Patients with Parkinson’s Disease: Real-World Evidence from a Nationwide Japanese Database over 10 Years (2008-2019) (2022) (0)
- Prospective Five-Year Follow-Up of Patients with Schizophrenia Suspected with Parkinson's Disease (2022) (0)
- [Progress in studies of Parkinson's disease]. (2000) (0)
- A Key Role of Soluble Epoxide Hydrolase in the Pathogenesis of Parkinson's Disease (2018) (0)
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What Schools Are Affiliated With Nobutaka Hattori?
Nobutaka Hattori is affiliated with the following schools:
