Norbert Suttorp

Q: What Schools Are Affiliated With Norbert Suttorp

Norbert Suttorp is affiliated with the following schools: Humboldt University of Berlin, Free University of Berlin, Technical University of Munich, University of Giessen

Norbert Suttorp's AcademicInfluence.com Rankings

Norbert Suttorp

Physics

#5131

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#6915

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Physics

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Norbert Suttorp's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19 (2020) (936)
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment (2020) (894)
Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation (2006) (887)
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis (2020) (738)
Nucleotide-binding Oligomerization Domain Proteins Are Innate Immune Receptors for Internalized Streptococcus pneumoniae* (2004) (364)
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection (2020) (321)
IFNβ induction by influenza A virus is mediated by RIG‐I which is regulated by the viral NS1 protein (2007) (301)
Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes (2008) (289)
CRB‐65 predicts death from community‐acquired pneumonia * (2006) (284)
Innate immune recognition in infectious and noninfectious diseases of the lung. (2010) (257)
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model (2020) (253)
The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia (2011) (252)
Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study (2021) (226)
Cardiovascular and inflammatory biomarkers to predict short- and long-term survival in community-acquired pneumonia: Results from the German Competence Network, CAPNETZ. (2010) (209)
Role of phosphodiesterases in the regulation of endothelial permeability in vitro. (1993) (205)
Nod1-Mediated Endothelial Cell Activation by Chlamydophila pneumoniae (2005) (203)
Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1β, Depending on Listeriolysin O and NLRP3 (2009) (203)
Listeria monocytogenes Activated p38 MAPK and Induced IL-8 Secretion in a Nucleotide-Binding Oligomerization Domain 1-Dependent Manner in Endothelial Cells1 (2006) (202)
Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium. (1990) (200)
Community-acquired Legionella pneumonia: new insights from the German competence network for community acquired pneumonia. (2008) (197)
Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells. (2000) (196)
VEGF induces hyperpermeability by a direct action on endothelial cells. (1998) (194)
Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. (2004) (194)
Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae. (1999) (193)
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid (2016) (191)
Outcome of community-acquired pneumonia: influence of age, residence status and antimicrobial treatment (2008) (188)
Adrenomedullin Reduces Endothelial Hyperpermeability (2002) (184)
Antioxidant defense mechanisms of endothelial cells: glutathione redox cycle versus catalase. (1986) (183)
Avoiding invasive mechanical ventilation by extracorporeal carbon dioxide removal in patients failing noninvasive ventilation (2012) (180)
p38 MAP Kinase—a molecular switch between VEGF‐induced angiogenesis and vascular hyperpermeability (2003) (177)
Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors (2020) (176)
Recognition of Streptococcus pneumoniae by the innate immune system (2012) (174)
Effect of omalizumab treatment on peripheral eosinophil and T-lymphocyte function in patients with allergic asthma. (2006) (164)
Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen recognition and signal transduction (2006) (156)
Influenza A Viruses Target Type II Pneumocytes in the Human Lung (2012) (149)
Community-acquired pneumonia through Enterobacteriaceae and Pseudomonas aeruginosa: diagnosis, incidence and predictors (2009) (149)
Suppression of pulmonary innate host defence in smokers (2007) (147)
Legionella pneumophila Induces IFNβ in Lung Epithelial Cells via IPS-1 and IRF3, Which Also Control Bacterial Replication* (2006) (141)
NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells1 (2008) (138)
CEACAM1 inhibits Toll-like receptor 2–triggered antibacterial responses of human pulmonary epithelial cells (2008) (137)
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis (2021) (136)
Bacterial exotoxins and endothelial permeability for water and albumin in vitro. (1988) (134)
Tumor necrosis factor-alpha-dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability. (2005) (132)
Serum glucose levels for predicting death in patients admitted to hospital for community acquired pneumonia: prospective cohort study (2012) (131)
Streptococcus pneumoniae-induced p38 MAPK-dependent Phosphorylation of RelA at the Interleukin-8 Promotor* (2004) (131)
Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia (2006) (129)
Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation. (2002) (126)
Statins Control Oxidized LDL-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells (2009) (125)
Intravenous Artesunate for Severe Malaria in Travelers, Europe (2011) (124)
Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability. (1996) (124)
Communicable Diseases Prioritized for Surveillance and Epidemiological Research: Results of a Standardized Prioritization Procedure in Germany, 2011 (2011) (122)
Noncytolytic terminal complement complexes may serve as calcium gates to elicit leukotriene B4 generation in human polymorphonuclear leukocytes. (1986) (121)
Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia* (2009) (120)
Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs (2012) (119)
Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger‐like mechanism and initiates a TLR2‐ and partly NOD1‐dependent inflammatory immune response (2007) (118)
Rho protein inactivation induced apoptosis of cultured human endothelial cells. (2002) (117)
Lung cell oxidant injury. Enhancement of polymorphonuclear leukocyte-mediated cytotoxicity in lung cells exposed to sustained in vitro hyperoxia. (1982) (110)
[SARS--Severe Acute Respiratory syndrome]. (2003) (110)
IFNβ responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM‐1/DAI) (2008) (109)
Role of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections (2009) (108)
Differential Antiviral Response of Endothelial Cells after Infection with Pathogenic and Nonpathogenic Hantaviruses (2004) (108)
A permissive role for tumor necrosis factor in vascular endothelial growth factor-induced vascular permeability. (2001) (108)
Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses (2018) (106)
Staphylococcal alpha-toxin-induced PGI2 production in endothelial cells: role of calcium. (1985) (105)
Induction of Phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in Human Peripheral Blood T-lymphocytes by 8-Bromo-cAMP and Gs-coupled Receptor Agonists (1998) (104)
Ultra-fast proteomics with Scanning SWATH (2021) (103)
Adrenomedullin and endothelial barrier function (2007) (100)
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. (2013) (100)
Intracellular Bacteria Differentially Regulated Endothelial Cytokine Release by MAPK-Dependent Histone Modification1 (2005) (100)
CAPNETZ—Community-Acquired Pneumonia Competence Network (2004) (98)
Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. (2006) (98)
Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling (2017) (95)
Pro-atrial natriuretic peptide and pro-vasopressin to predict severity and prognosis in community-acquired pneumonia (2007) (94)
Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells (1993) (92)
Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells. (1999) (91)
Streptococcus pneumoniae-Induced Caspase 6-Dependent Apoptosis in Lung Epithelium (2004) (91)
Infection and activation of airway epithelial cells by Chlamydia pneumoniae. (2000) (90)
Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock (2007) (89)
Bartonella henselae Induces NF-κB-Dependent Upregulation of Adhesion Molecules in Cultured Human Endothelial Cells: Possible Role of Outer Membrane Proteins as Pathogenic Factors (2001) (89)
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice (2011) (89)
Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal alpha-toxin. (1997) (87)
Effects of Escherichia coli hemolysin on endothelial cell function (1990) (85)
Staphylococcal alpha-toxin-induced vascular leakage in isolated perfused rabbit lungs. (1990) (85)
Mycoplasma pneumoniae pneumonia revisited within the German Competence Network for Community-acquired pneumonia (CAPNETZ) (2009) (85)
Impact of intravenous {beta}-lactam/macrolide versus {beta}-lactam monotherapy on mortality in hospitalized patients with community-acquired pneumonia. (2009) (82)
Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells (2010) (82)
A time-resolved proteomic and prognostic map of COVID-19 (2021) (79)
Histone Acetylation and Flagellin Are Essential for Legionella pneumophila-Induced Cytokine Expression1 (2008) (79)
The Burden of Pneumococcal Pneumonia – Experience of the German Competence Network CAPNETZ (2012) (78)
Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reduction. (2006) (78)
Pro-atrial natriuretic peptide and pro-vasopressin for predicting short-term and long-term survival in community-acquired pneumonia: results from the German Competence Network CAPNETZ (2010) (78)
Cerebral toxocariasis after consumption of raw duck liver. (2007) (76)
CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction (2015) (76)
Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils. (1991) (75)
Community-acquired pneumonia as medical emergency: predictors of early deterioration (2015) (74)
Rho protein inhibition blocks protein kinase C translocation and activation. (1998) (72)
Simvastatin attenuates ventilator-induced lung injury in mice (2010) (72)
Complement activation induces excessive T cell cytotoxicity in severe COVID-19 (2021) (71)
Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin (1987) (71)
Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives (2014) (71)
Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro. (1991) (70)
Perturbation of endothelial junction proteins by Staphylococcus aureus α-toxin: inhibition of endothelial gap formation by adrenomedullin (2006) (70)
Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin (2014) (69)
Schistosomiasis in European Travelers and Migrants: Analysis of 14 Years TropNet Surveillance Data. (2017) (67)
Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: Membrane attack and calcium influx (1985) (66)
Thromboxane-mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs. (1989) (65)
Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells (2006) (65)
Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function. (1997) (65)
Malarone treatment failure not associated with previously described mutations in the cytochrome b gene (2004) (65)
Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium. (2006) (65)
Adrenomedullin attenuates ventilator-induced lung injury in mice (2010) (64)
Hydrogen peroxide-induced increase in lung endothelial and epithelial permeability--effect of adenylate cyclase stimulation and phosphodiesterase inhibition. (1995) (63)
Immunostimulation with macrophage-activating lipopeptide-2 increased survival in murine pneumonia. (2009) (63)
NOD-Like Receptors in Lung Diseases (2013) (63)
β-PIX and Rac1 GTPase Mediate Trafficking and Negative Regulation of NOD21 (2008) (61)
Complement complex C5b-8 induces PGI2 formation in cultured endothelial cells. (1987) (61)
Antibiotic treatment–induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia (2018) (61)
Escherichia coli hemolysin and Staphylococcus aureas alpha-toxin potently induce neutrophil adhesion to cultured human endothelial cells. (1996) (60)
Streptococcus pneumoniae R6x induced p38 MAPK JNK-mediated Caspase-dependent apoptosis in human endothelial cells (2005) (60)
Porphyromonas gingivalis Strain-Dependent Activation of Human Endothelial Cells (2004) (60)
The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue (2013) (59)
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany (2021) (59)
Listeria monocytogenes potently induces up-regulation of endothelial adhesion molecules and neutrophil adhesion to cultured human endothelial cells. (1997) (59)
Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia. (2013) (58)
Extra- and intracellular innate immune recognition in endothelial cells (2007) (57)
Adrenomedullin reduces Staphylococcus aureus &agr;-toxin–induced rat ileum microcirculatory damage (2005) (56)
Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study (2011) (54)
Influenza vaccination is associated with reduced severity of community-acquired pneumonia (2010) (53)
Sensitivity of hemozoin detection by automated flow cytometry in non‐ and semi‐immune malaria patients (2003) (53)
Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia (2017) (53)
Legionella pneumophila-induced NF-κB- and MAPK-dependent cytokine release by lung epithelial cells (2006) (52)
Streptococcus pneumoniae induces human β-defensin-2 and -3 in human lung epithelium (2012) (52)
RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice. (2010) (52)
Differences in Cell Activation by Chlamydophila pneumoniae and Chlamydia trachomatis Infection in Human Endothelial Cells (2004) (52)
Severe malaria in Europe: an 8-year multi-centre observational study (2017) (51)
Essential Role of Mitochondrial Antiviral Signaling, IFN Regulatory Factor (IRF)3, and IRF7 in Chlamydophila pneumoniae-Mediated IFN-β Response and Control of Bacterial Replication in Human Endothelial Cells (2010) (51)
Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19) (2020) (51)
Two distinct phospholipases C of Listeria monocytogenes induce ceramide generation, nuclear factor-kappa B activation, and E-selectin expression in human endothelial cells. (1998) (51)
Evaluation of PEEP and prone positioning in early COVID-19 ARDS (2020) (50)
A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection. (2016) (49)
Induction of human β-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-κB, and AP-1. (2010) (49)
Prognostic and Pathogenic Role of Angiopoietin‐1 and ‐2 in Pneumonia (2018) (48)
Reduction of tumor necrosis factor-alpha (TNF-α) related nuclear factor-kappaB (NF-κB) translocation but not inhibitor kappa-B (Iκ-B)-degradation by Rho protein inhibition in human endothelial cells (2002) (48)
Assessment of inflammatory markers in patients with community-acquired pneumonia--influence of antimicrobial pre-treatment: results from the German competence network CAPNETZ. (2010) (47)
Allergic lung inflammation induces pulmonary vascular hyperresponsiveness (2006) (46)
How deadly is seasonal influenza-associated pneumonia? The German Competence Network for Community-Acquired Pneumonia (2010) (46)
Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue (2012) (46)
Human Pulmonary 3D Models For Translational Research (2017) (46)
Malaria transmission in non-endemic areas: case report, review of the literature and implications for public health management (2009) (46)
Streptococcus pneumoniae-Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol. (2015) (46)
Simvastatin Reduces Chlamydophila pneumoniae–Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells (2008) (46)
Interaction of pathogens with the endothelium (2003) (45)
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model (2020) (45)
Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality (2016) (45)
Studying the pathophysiology of coronavirus disease 2019 - a protocol for the Berlin prospective COVID-19 patient cohort (Pa- COVID-19) (2020) (45)
Assessment of oxygenation and comorbidities improves outcome prediction in patients with community‐acquired pneumonia with a low CRB‐65 score (2015) (44)
A haemorrhagic fever from the Côte d'lvoire (1999) (44)
The C-Type Lectin Receptor Mincle Binds to Streptococcus pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response (2015) (43)
The Sphingosine-1 Phosphate receptor agonist FTY720 dose dependently affected endothelial integrity in vitro and aggravated ventilator-induced lung injury in mice. (2011) (43)
Role of local pulmonary IFN-gamma expression in murine allergic airway inflammation. (2006) (42)
Chlamydophila pneumoniae (2005) (42)
Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells (2012) (42)
Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia – results from the prospective observational PROGRESS study (2019) (42)
Long-term immunogenicity of BNT162b2 vaccination in older people and younger health-care workers (2021) (42)
Human neutrophil elastase increases permeability of cultured pulmonary endothelial cell monolayers. (1993) (42)
Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA (2018) (41)
The “Choosing Wisely” initiative in infectious diseases (2016) (41)
Dysnatremia, vasopressin, atrial natriuretic peptide and mortality in patients with community-acquired pneumonia: results from the german competence network CAPNETZ. (2014) (41)
Legionella pneumophila-induced PKC, P38 MAPK and NF-kB dependent COX-2 expression in human lung epithelium (2006) (40)
Mechanisms of Chlamydophila pneumoniae-mediated GM-CSF release in human bronchial epithelial cells. (2006) (40)
Differential activation of dendritic cells by nerve growth factor and brain‐derived neurotrophic factor (2007) (40)
Relative frequency of malaria pigment-carrying monocytes of nonimmune and semi-immune patients from flow cytometric depolarized side scatter. (2001) (40)
The glutathione redox cycle as a defense system against hydrogen-peroxide-induced prostanoid formation and vasoconstriction in rabbit lungs. (1986) (40)
Innate Immune Recognition and Inflammasome Activation in Listeria Monocytogenes Infection (2010) (40)
Severity of respiratory failure and computed chest tomography in acute COVID-19 correlates with pulmonary function and respiratory symptoms after infection with SARS-CoV-2: An observational longitudinal study over 12 months (2021) (39)
Modifying Post-Operative Medical Care after EBV Implant May Reduce Pneumothorax Incidence (2015) (39)
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 (2021) (37)
Role of endothelial cytoskeleton in high-permeability edema due to botulinum C2 toxin in perfused rabbit lungs. (1995) (37)
Hemolysis after Oral Artemisinin Combination Therapy for Uncomplicated Plasmodium falciparum Malaria (2016) (36)
The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells. (2007) (36)
Effectiveness of Twice-Weekly Pyrimethamine-Sulfadoxine as Primary Prophylaxis of Pneumocystis carinii Pneumonia and Toxoplasmic Encephalitis in Patients with Advanced HIV Infection (2002) (36)
Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01 (2021) (36)
CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity (2021) (36)
C-terminal provasopressin (copeptin) in patients with community-acquired pneumonia--influence of antibiotic pre-treatment: results from the German competence network CAPNETZ. (2009) (36)
Effect of staphylococcal alpha-toxin on intracellular Ca2+ in polymorphonuclear leukocytes (1988) (35)
Homogeneous assay based on 52 primer sets to scan for mutations of the ABCA1 gene and its application in genetic analysis of a new patient with familial high-density lipoprotein deficiency syndrome. (2001) (35)
Suppressive myeloid cells are a hallmark of severe COVID-19 (2020) (35)
Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study. (2015) (35)
Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice (2014) (34)
Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness. (2009) (34)
Hyperpermeability of pulmonary endothelial monolayer: Protective role of phosphodiesterase isoenzymes 3 and 4 (2004) (34)
Tyk2 as a target for immune regulation in human viral/bacterial pneumonia (2017) (33)
Comparative transcriptional profiling of the lung reveals shared and distinct features of Streptococcus pneumoniae and influenza A virus infection (2007) (33)
Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia* (2009) (33)
Outcomes of Endobronchial Valve Treatment Based on the Precise Criteria of an Endobronchial Catheter for Detection of Collateral Ventilation under Spontaneous Breathing (2015) (33)
Rho Protein Inhibition Blocks Cyclooxygenase-2 Expression by Proinflammatory Mediators in Endothelial Cells (2003) (33)
Moraxella catarrhalis induces ERK- and NF-κB-dependent COX-2 and prostaglandin E2 in lung epithelium (2007) (33)
Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure (2020) (33)
TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia (2012) (32)
Single nucleotide polymorphism in 5'-flanking region reduces transcription of surfactant protein B gene in H441 cells. (2006) (32)
Impact of pneumococcal vaccination in children on serotype distribution in adult community-acquired pneumonia using the serotype-specific multiplex urinary antigen detection assay. (2016) (32)
Endotoxin alters arachidonate metabolism in pulmonary endothelial cells. (1987) (32)
Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue (2015) (32)
Adrenomedullin reduces intestinal epithelial permeability in vivo and in vitro. (2009) (32)
Role of platelet-activating factor in pneumolysin-induced acute lung injury (2007) (31)
Pharmacological and biochemical studies of cytotoxicity of Clostridium novyi type A alpha-toxin (1989) (31)
Omalizumab decreased IgE‐release and induced changes in cellular immunity in patients with allergic asthma (2006) (31)
Decreased bactericidal function and impaired respiratory burst in lung macrophages after sustained in vitro hyperoxia. (1983) (31)
The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires’ disease in humans (2018) (30)
Acute fascioliasis with multiple liver abscesses. (2000) (30)
Late-Onset Disseminated Mycobacterium avium intracellulare Complex Infection (MAC), Cerebral Toxoplasmosis and Salmonella Sepsis in a German Caucasian Patient with Unusual Anti-Interferon-Gamma IgG1 Autoantibodies (2015) (30)
Stimulation of PAF-synthesis in pulmonary artery endothelial cells by Staphylococcus aureus alpha-toxin. (1992) (29)
Lung cell oxidant injury: decrease in oxidant mediated cytotoxicity by N-acetylcysteine. (1985) (29)
Detection of allergen-induced airway hyperresponsiveness in isolated mouse lungs. (2006) (29)
Pulmonary Immunostimulation with MALP-2 in Influenza Virus-Infected Mice Increases Survival after Pneumococcal Superinfection (2015) (29)
Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies. (2016) (28)
Therapeutic strategies in pneumonia: going beyond antibiotics (2015) (27)
Lung perfusion and emphysema distribution affect the outcome of endobronchial valve therapy (2016) (27)
Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: the unknown connection (1994) (26)
Intermedin Stabilized Endothelial Barrier Function and Attenuated Ventilator-induced Lung Injury in Mice (2011) (26)
Regulation of interleukin IL-4, IL-13, IL-10, and their downstream components in lipopolysaccharide-exposed rat lungs. Comparison of the constitutive expression between rats and humans. (2006) (26)
Undiagnosed Diabetes Mellitus in Community-Acquired Pneumonia: A Prospective Cohort Study (2017) (26)
Reduction of tumor necrosis factor-alpha (TNF-alpha) related nuclear factor-kappaB (NF-kappaB) translocation but not inhibitor kappa-B (Ikappa-B)-degradation by Rho protein inhibition in human endothelial cells. (2002) (26)
Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia (2017) (26)
Localization and pneumococcal alteration of junction proteins in the human alveolar–capillary compartment (2017) (25)
Streptococcus Pneumoniae-induced P38 MAPK and NF-kB dependent COX-2 expression in human lung epithelium (2006) (25)
The microbiota in pneumonia: From protection to predisposition (2021) (25)
A new strategy for the prevention of IgA anaphylactic transfusion reactions (2004) (25)
Pathogenesis of sepsis syndrome: possible relevance of pore-forming bacterial toxins. (1996) (25)
A proteomic survival predictor for COVID-19 patients in intensive care (2021) (24)
Role of membrane lipids in the pulmonary vascular abnormalities caused by bacterial toxins. (1987) (24)
Twice-weekly pyrimethamine-sulfadoxine effectively prevents Pneumocystis carinii pneumonia relapse and toxoplasmic encephalitis in patients with AIDS. (2001) (24)
Interaction of human neutrophils with airway epithelial cells: Reduction of leukotriene B4 generation by epithelial cell derived prostaglandin E2 (1998) (23)
TLR2- and Nucleotide-Binding Oligomerization Domain 2-Dependent Krüppel-Like Factor 2 Expression Downregulates NF-κB–Related Gene Expression (2010) (23)
Role of Ca2+ and Mg2+ for endothelial permeability of water and albumin in vitro. (1989) (23)
Regulation of NGF and BDNF by dexamethasone and theophylline in human peripheral eosinophils in allergics and non-allergics (2005) (22)
Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms (2008) (22)
NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence (2016) (22)
Legionella pneumophila induces human beta Defensin-3 in pulmonary cells (2010) (22)
Development and evaluation of an implementation strategy for the German guideline on community-acquired pneumonia (2010) (22)
Domestic Cholera in Germany Associated with Fresh Fish Imported from Nigeria (2002) (21)
Cell-specific interleukin-15 and interleukin-15 receptor subunit expression and regulation in pneumococcal pneumonia--comparison to chlamydial lung infection. (2007) (21)
Moraxella catarrhalis--infected alveolar epithelium induced monocyte recruitment and oxidative burst. (2005) (21)
Moxifloxacin monotherapy versus ß-lactam mono- or combination therapy in hospitalized patients with community-acquired pneumonia. (2011) (21)
[What is new in the treatment of community-acquired pneumonia?]. (2006) (20)
Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis. (2020) (20)
Community-acquired Haemophilus influenzae pneumonia--New insights from the CAPNETZ study. (2016) (20)
Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells. (2006) (20)
Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany. (2010) (20)
Legionella pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 expression in human lung epithelium. (2007) (20)
Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients: results from a prospective observational study (2021) (20)
Selective induction of nerve growth factor and brain‐derived neurotrophic factor by LPS and allergen in dendritic cells (2008) (20)
Critical Illness and Systemic Inflammation Are Key Risk Factors of Severe Acute Kidney Injury in Patients With COVID-19 (2021) (20)
Human African trypanosomiasis with 7-year incubation period: clinical, laboratory and neuroimaging findings. (2014) (20)
MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation. (2016) (19)
Reactogenicity of homologous and heterologous prime-boost immunization with BNT162b2 and ChAdOx1-nCoV19: a prospective cohort study (2021) (19)
Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study (2021) (19)
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Endoskopische Lungenvolumenreduktion: Können Ventile sicher entfernt werden? (2016) (0)
Die Effekte der Syk-Inhibition auf die pulmonale Vasokonstriktion (2019) (0)
Der pulmonale Herd (2020) (0)
17 Infektionen von Knochen und Gelenken (2004) (0)
Systembiologische Analyse der klassischen und alternativen Makrophagenaktivierung (2011) (0)
Bakterielle DNA induziert IL-10 über TLR9 und Src-Kinasen abhängige Expression des Transkriptionsfaktors Krüppel-like-factor-4 (KLF4) (2009) (0)
Rolle von COX2 und PGE2 in der S. pneumoniae induzierten Infektion in humanem Lungengewebe (2010) (0)
11 Infektionen der Niere und der ableitenden Harnwege (2004) (0)
Apoptoseverlauf bei der schweren Pneumokokkenpneumonie mit Sepsis und akutem Lungenversagen (2005) (0)
Sputum und Urin-Pneumokokken-Antigen-Test in der Diagnostik der ambulant erworbenen Pneumokokken Pneumonie (2008) (0)
Legionella pneumophila induziert p38 MAP-Kinasen- und NF-κB-abhängige Freisetzung von Interleukin 8 in humanen Alveolarepithelzellen (2005) (0)
Prognostischer Wert von CRB-65 Score und Procalcitonin bei ambulant erworbener Pneumonie (2007) (0)
Die allergische Inflammation der Lunge induziert pulmonalvaskuläre Hyperreagibilität (2006) (0)
Priorisierung übertragbarer Infektionserregerunter dem Aspekt der Surveillance undepidemiologischen Forschung (2011) (0)
DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages (2018) (0)
Krüppel-like Factor 2 terminiert die Streptococcus pneumoniae-induzierte pro-inflammatorischen Antwort in humanen bronchial Epithelzellen (2011) (0)
Auswirkungen des Corona-Lockdowns auf Gesundheitszustand- und verhalten von Patient*innen mit schwerer COPD – Daten aus einer monozentrischen Beobachtungsstudie der Charité Universitätsmedizin, Berlin (2021) (0)
Differentielles Infektionsverhalten human-pathogener, porciner und aviärer Influenza A Viren in humanen Lungen (2010) (0)
Ambulant erworbene Pneumonie (2017) (0)
Das ex vivo Modell der humanen Lunge in der Pneumonieforschung (2019) (0)
Schwere Ambulant Erworbene Pneumonie – Neue Erkenntnisse durch CAPNETZ (2007) (0)
Anti-inflammatory strategies in acute lung injury (2011) (0)
Adrenomedullin senkt pulmonalvaskuläre Permeabilität und verhindert renale Dysfunktion im Ventilator-induced lung injury (2009) (0)
Krankenhauseinweisungen bei primär ambulant therapierten Patienten mit CAP: Risikofaktoren und Verlauf (2008) (0)
S. pneumoniae induziert die Phosphorylierung von p65/RelA am Promotor des il-8-Gens in Abhängigkeit der p38 MAP-Kinase (2005) (0)
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19 (2022) (0)
Expression pattern of CEA-related cell adhesion molecules in human pulmonary epithelia in relation to inflammatory stimuli and to the interaction with Moraxella catarrhalis (2010) (0)
Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation (2020) (0)
13 Infektionen des Herzens und der Gefäße (2004) (0)
Stimulation of arachidonate metabolism by endotoxin and the terminal complement complex C5b-8. (1989) (0)
of concurrent Differences in Clinical Manifestations of Imported versus Autochthonous Leptospirosis in Austria and Germany (2010) (0)
Paratial anomalous pulmonary venous connection in a patient with cardiac failure and sepsis (2006) (0)
Streptococcus pneumoniaeInduced Alpha-Melanocyte Stimulating Hormone in Infected Human Bronchial Epithelial Cells. (2009) (0)
Regulators of Neutrophilic Inflammation in Community Acquired Pneumonia (2018) (0)
Streptococcus pneumoniae induced alpha-Melanocyte Stimulating Hormone in infected human bronchial epithelial cells (2008) (0)
Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation. (2022) (0)
[42-year-old woman with progressive dyspnea, lower limb swelling and skin lesions]. (2012) (0)
[Therapy and prevention of infectious diseases]. (2014) (0)
Expression Plasmids and HEK 293 Cell Overexpression Experiments (2005) (0)
Adrenomedullin Reduces Sepsis-Related Intestinal Epithelial PermeabilityIn VivoandIn Vitro. (2009) (0)
Surface proteome of plasma extracellular vesicles as biomarkers for pneumonia and acute exacerbation of COPD (2020) (0)
From Molecular Science to the Treatment of Allergy (1999) (0)
Inhalativer Einsatz unformulierter siRNA zur pulmonalen Regulation konstitutiver und Pneumonie-induzierter Genexpression in der Maus (2009) (0)
Prediction of 28 day mortality and need for ICU treatment in the PROGRESS Study by CAP severity scores (2018) (0)
L. pneumophila activated different IFN-regulated factors and induced IFNb expression (2006) (0)
Inhalative use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia (2011) (0)
NOD PROTEINS ARE INNATE IMMUNE RECEPTORS FOR STREPTOCOCCUS PNEUMONIAE: 82 (2004) (0)
Falciparum malaria and Tangier disease [letter] (2003) (0)

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