Noreen Murray
#15,052
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British molecular biologist
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Noreen Murraybiology Degrees
Biology
#632
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#1112
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Molecular Biology
#96
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#99
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Biochemistry
#1865
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#2006
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Biology
Why Is Noreen Murray Influential?
(Suggest an Edit or Addition)According to Wikipedia, Noreen Elizabeth, Lady Murray was an English molecular geneticist who helped pioneer recombinant DNA technology by creating a series of bacteriophage lambda vectors into which genes could be inserted and expressed in order to examine their function. During her career she was recognised internationally as a pioneer and one of Britain's most distinguished and highly respected molecular geneticists. Until her 2001 retirement she held a personal chair in molecular genetics at the University of Edinburgh. She was president of the Genetical Society, vice president of the Royal Society, and a member of the UK Science and Technology Honours Committee.
Noreen Murray's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Lambda replacement vectors carrying polylinker sequences. (1983) (1447)
- A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. (2003) (701)
- Restriction and modification systems. (1991) (668)
- Sequence diversity among related genes for recognition of specific targets in DNA molecules. (1983) (440)
- Type I Restriction Systems: Sophisticated Molecular Machines (a Legacy of Bertani and Weigle) (2000) (388)
- McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. (1988) (324)
- Phage lambda receptor chromosomes for DNA fragments made with restriction endonuclease III of Haemophilus influenzae and restriction endonuclease I of Escherichia coli. (1975) (297)
- Highlights of the DNA cutters: a short history of the restriction enzymes (2013) (234)
- Manipulation of restriction targets in phage λ to form receptor chromosomes for DNA fragments (1974) (196)
- Experimental Methods for Use with Lambda (1983) (177)
- Phage Lambda and Molecular Cloning (1983) (162)
- 2001 Fred Griffith review lecture. Immigration control of DNA in bacteria: self versus non-self. (2002) (155)
- Lambdoid phages that simplify the recovery of in vitro recombinants (1977) (153)
- Nucleoside triphosphate-dependent restriction enzymes. (2001) (153)
- Molecular cloning of the DNA ligase gene from bacteriophage T4. II. Amplification and preparation of the gene product. (1979) (129)
- The construction in vitro of transducing derivatives of phage lambda (1976) (105)
- Recognition sequence of a restriction enzyme. (1973) (95)
- The evolution of gene clusters and genetic circularity in microorganisms. (1966) (94)
- Convergent transcription in bacteriophage λ: Interference with gene expression☆ (1979) (93)
- A mutational analysis of the two motifs common to adenine methyltransferases. (1994) (91)
- Reassortment of DNA recognition domains and the evolution of new specificities (1987) (90)
- Purification and characterization of the methyltransferase from the type 1 restriction and modification system of Escherichia coli K12. (1993) (86)
- Molecular cloning of the DNA ligase gene from bacteriophage T4. I. Characterisation of the recombinants. (1979) (84)
- The diversity of alleles at the hsd locus in natural populations of Escherichia coli. (1995) (84)
- Genetic recombination can generate altered restriction specificity. (1984) (83)
- On the structure and operation of type I DNA restriction enzymes. (1999) (82)
- Structural homologies among type I restriction‐modification systems. (1982) (79)
- Organization and sequence of the hsd genes of Escherichia coli K-12. (1987) (77)
- Polarized recombination and fine structure within the me-2 gene of Neurospora crassa. (1963) (75)
- Regulation of endonuclease activity by proteolysis prevents breakage of unmodified bacterial chromosomes by type I restriction enzymes. (1999) (70)
- Roles of selection and recombination in the evolution of type I restriction-modification systems in enterobacteria. (1992) (69)
- Two DNA recognition domains of the specificity polypeptides of a family of type I restriction enzymes. (1986) (66)
- Conservation of complex DNA recognition domains between families of restriction enzymes (1989) (65)
- EcoA and EcoE: alternatives to the EcoK family of type I restriction and modification systems of Escherichia coli. (1985) (63)
- Conservation of organization in the specificity polypeptides of two families of type I restriction enzymes. (1989) (63)
- Restriction by EcoKI is enhanced by co‐operative interactions between target sequences and is dependent on DEAD box motifs. (1996) (60)
- The DNA translocation and ATPase activities of restriction-deficient mutants of Eco KI. (1999) (60)
- ClpX and ClpP are essential for the efficient acquisition of genes specifying type IA and IB restriction systems (1998) (58)
- Enhanced recovery and restriction mapping of DNA fragments cloned in a new λ vector (1988) (58)
- Conservation of motifs within the unusually variable polypeptide sequences of type I restriction and modification enzymes (1993) (57)
- Mutations that confer de novo activity upon a maintenance methyltransferase. (1991) (57)
- Physical characterisation of the “Rac prophage” in E. coli K12 (1979) (55)
- Modification enhancement by the restriction alleviation protein (Ral) of bacteriophage lambda. (1986) (54)
- Restriction of bacteriophage λ by Escherichia coli K (1973) (53)
- T4 polynucleotide kinase; cloning of the gene (pseT) and amplification of its product. (1985) (53)
- DNA recognition by the EcoK methyltransferase. The influence of DNA methylation and the cofactor S-adenosyl-L-methionine. (1993) (52)
- Restriction enzymes in cells, not eppendorfs. (1994) (52)
- Restriction alleviation and modification enhancement by the Rac prophage of Escherichia coli K‐12 (1995) (50)
- The restriction-modification genes of Escherichia coli K-12 may not be selfish: they do not resist loss and are readily replaced by alleles conferring different specificities. (1997) (48)
- EcoKI with an amino acid substitution in any one of seven DEAD-box motifs has impaired ATPase and endonuclease activities. (1998) (46)
- Characterization of λtrp-transducing bacteriophages made in vitro (1976) (45)
- High efficiency, restriction-deficient in vitro packaging extracts for bacteriophage lambda DNA using a new E.coli lysogen. (1993) (45)
- Distribution and diversity of hsd genes in Escherichia coli and other enteric bacteria (1988) (44)
- Is modification sufficient to protect a bacterial chromosome from a resident restriction endonuclease? (2003) (43)
- Intergenic cis-trans position effects in bacteriophage T4. (1966) (40)
- Families of restriction enzymes: an analysis prompted by molecular and genetic data for type ID restriction and modification systems. (2001) (40)
- Sequence-specific DNA binding by EcoKI, a type IA DNA restriction enzyme. (1998) (39)
- The proteolytic control of restriction activity in Escherichia coli K‐12 (2001) (39)
- Manipulation of restriction targets in phage lambda to form receptor chromosomes for DNA fragments. (1974) (38)
- The hsd (host specificity) genes of E. coli K12 (2004) (37)
- Terminal nucleotide sequences of DNA from temperate coliphages. (1973) (36)
- Control of the endonuclease activity of type I restriction‐modification systems is required to maintain chromosome integrity following homologous recombination (2006) (35)
- A third family of allelic hsd genes in Salmonella enterica: sequence comparisons with related proteins identify conserved regions implicated in restriction of DNA (1997) (34)
- Reversal of polarized recombination of alleles in Neurospora as a function of their position. (1969) (34)
- Polarized intragenic recombination in chromosome rearrangements of Neurospora. (1968) (33)
- A third family of allelic hsd genes in Salmonella enterica: sequence comparisons with related proteins identify conserved regions implicated in restriction of DNA (1996) (33)
- Isolation and characterization of a lambdapolA transducing phage. (1977) (32)
- Localization of a protein‐DNA interface by random mutagenesis (1998) (31)
- S-adenosyl methionine alters the DNA contacts of the EcoKI methyltransferase. (1995) (29)
- Tyrosine 27 of the specificity polypeptide of EcoKI can be UV crosslinked to a bromodeoxyuridine-substituted DNA target sequence. (1995) (28)
- Complementation and recombination between Methionine-2 alleles in Neurospora crassa (1960) (28)
- Convergent transcription in bacteriophage lambda: interference with gene expression. (1979) (28)
- Lambda phage vectors--EMBL series. (1987) (27)
- Molecular cloning of fragments of bacteriophage T4 DNA (1977) (27)
- The specificity of sty SKI, a type I restriction enzyme, implies a structure with rotational symmetry. (1997) (26)
- DNA targets for the Escherichia coli K restriction system analysed genetically in recombinants between phages Phi80 and lambda (1973) (24)
- Restriction of λtrp bacteriophages by Escherichia coli K (1974) (24)
- Recombination events that span sites within neighbouring gene loci of Neurospora. (1970) (24)
- Cysteine mutant strains of Neurospora. (1965) (23)
- The trpE gene of Escherichia coli K contains a recognition sequence for the K-restriction system. (1973) (21)
- Target recognition by EcoKI: the recognition domain is robust and restriction-deficiency commonly results from the proteolytic control of enzyme activity. (2001) (21)
- What has phage lambda ever done for us? (2007) (18)
- On the nature of sbcA mutations in E. coli K12 (2004) (17)
- Base changes in the recognition site for ter functions in lambdoid phage DNA (1975) (15)
- The distribution of methionine loci in Neurospora crassa (1960) (15)
- [12] Special uses of γ phage for molecular cloning (1991) (14)
- Restriction of bacteriophage lambda by Escherichia coli K. (1973) (14)
- The impact of phage lambda: from restriction to recombineering. (2006) (12)
- Enhanced recovery and restriction mapping of DNA fragments cloned in a new lambda vector. (1988) (12)
- Restriction of lambda trp bacteriophages by Escherichia coli K. (1974) (11)
- Construction and characterization of Escherichia coli polA-lacZ gene fusions (1980) (10)
- Characterization of λpolA transducing phages; Effective expression of the E. coli polA gene (1979) (10)
- Characterization of lambdatrp-transducing bacteriophages made in vitro. (1976) (9)
- Molecular cloning of the T4 genome; Organization and expression of the frd-DNA ligase region (2004) (9)
- The assembly of the EcoKI type I DNA restriction/modification enzyme and its interaction with DNA. (1999) (8)
- DNA Restriction and Modification (2009) (7)
- McrAandMcrBrestriction phenotypes ofsomeE.coli strains andimplications forgenecloning (1987) (7)
- Defining domains in type-I restriction and modification enzymes. (1988) (7)
- Characterization of lambdapolA transducing phages; effective expression of the E. coli polA gene. (1979) (4)
- Gamma-T4 hybrid bacteriophage carrying the thymidine kinase gene of bacteriophage T4 (1984) (4)
- Special uses of lambda phage for molecular cloning. (1991) (3)
- Modification enhancement and restriction alleviation by bacteriophage λ (1995) (3)
- 16 – λ Phage Vectors—EMBL Series (1989) (3)
- Linkage information for cysteine and methionine mutants (1968) (3)
- Mutational analysis of conserved amino-acid motifs in EcoKI adenine methyltransferase. (1995) (2)
- Explorer Nucleoside triphosphate-dependent restriction enzymes (2001) (2)
- Alternative hosts for genetic engineers (1982) (1)
- Assembly of the multifunctional EcoKI DNA restriction enzyme in vitro (1997) (1)
- Modification enhancement and restriction alleviation by bacteriophage lambda. (1995) (1)
- Recombinant DNA (2nd edn): James D. Watson, Michael Gilman, Jan Witkowski and Mark Zoller W.H. Freeman, 1992. £35.95 hbk, £21.95 pbk (xiv + 626 pages) ISBN 0 7167 1994 0 (1993) (1)
- Complementation and recombination studies on me-2 alleles of Neurospora crassa. (1960) (1)
- Everyman's guide to molecular cloning (1982) (1)
- Proteolytic Control of Restriction by the Type I Restriction Enzyme EcoKI (2000) (1)
- APPENDIX III Lambda Vectors (1983) (0)
- Gene cloning (1996) (0)
- Isolation and characterization of a XpolA transducing phage ( DNA polymerase I / gene amplification / in vitro recombinants ) (0)
- Some genetic interrelations of methionine mutants of Neurospora crassa (1959) (0)
- TYPE-1 RESTRICTION ENZYMES OF ENTERIC BACTERIA (1993) (0)
- A second 'leaky' histidine mutant in linkage group IV (1962) (0)
- Encyclopedia of Microbiology (2009) (0)
- The bacteriopage, Vols and 2: Edited R. Calendar, Plenum Press, 1988. $105.00/$125.00 (xviii + 596/xviii + 760 pages) ISBN 0 306 42730 3/0 306 42853 9 (1989) (0)
- Molecular Cloning of the Pyruvate Dehydrogenase Complex Genes of Escherichia coli (2008) (0)
- PHAGES AS CLONING VEHICLES (1999) (0)
- APPLICATION OF RECOMBINANT DNA TECHNOLOGY TO THE MOLECULAR GENETICS OF PROKARYOTES (1979) (0)
- Discovering Molecular Genetics: A Case Study Course with Problems & Scenarios. By Jeffrey H. Miller. Cold Spring Harbor. 1995. 700 pages. Price $59.00cloth. ISBN 0-87969-475-0. (1996) (0)
- Prokaryotic Gene Expression (Frontiers in Molecular Biology Series, 21) (2000) (0)
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