Oliver F. W. James
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Oliver F. W. Jamesphilosophy Degrees
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Philosophy
Oliver F. W. James's Degrees
- PhD Biochemistry Stanford University
- Doctorate Medicine Stanford University
Why Is Oliver F. W. James Influential?
(Suggest an Edit or Addition)Oliver F. W. James's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Steatohepatitis: a tale of two "hits"? (1998) (3951)
- Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver (1995) (456)
- Natural history of early primary biliary cirrhosis (1996) (402)
- Hepatic steatosis: Innocent bystander or guilty party? (1998) (395)
- Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance. (1998) (373)
- Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years. (2002) (312)
- Non-alcoholic steatohepatitis: another disease of affluence (1999) (281)
- PRIMARY BILIARY CIRRHOSIS: IDENTIFICATION OF TWO MAJOR M2 MITOCHONDRIAL AUTOANTIGENS (1988) (278)
- Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis. (1988) (263)
- Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort (2004) (238)
- Effects of age and gender on in vitro properties of human liver microsomal monooxygenases (1990) (219)
- Familial primary biliary cirrhosis reassessed: a geographically-based population study. (1999) (211)
- Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis (2005) (209)
- The true impact of fatigue in primary biliary cirrhosis: a population study. (2002) (208)
- Primary biliary cirrhosis once rare, now common in the United Kingdom? (1999) (206)
- A controlled trial of prednisolone treatment in primary biliary cirrhosis. Three-year results. (1992) (195)
- CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. (2000) (176)
- Patterns of autoimmunity in primary biliary cirrhosis patients and their families: a population-based cohort study. (2004) (175)
- Incidence and prevalence of primary biliary cirrhosis in the city of Newcastle upon Tyne, England. (1997) (172)
- A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis. (2007) (163)
- The geographical distribution of primary biliary cirrhosis in a well‐defined cohort (2001) (162)
- Guidelines for selection of patients for liver transplantation in the era of donor-organ shortage (1999) (162)
- Hepatocellular carcinoma in primary biliary cirrhosis and its impact on outcomes (1997) (156)
- Case–control studies of risk factors for primary biliary cirrhosis in two United Kingdom populations (2010) (154)
- Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region. (1990) (151)
- The association of age and frailty with paracetamol conjugation in man. (1990) (146)
- Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use. (2000) (142)
- Effects of physical activity and age on mitochondrial function. (1996) (139)
- The epidemiology of primary biliary cirrhosis. (2003) (137)
- An exploratory population‐based case‐control study of primary biliary cirrhosis (2000) (127)
- HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility (2001) (119)
- The epidemiology of primary biliary cirrhosis in north-east England: an increasingly common disease? (1990) (115)
- Mortality and Recovery After Stroke in The Gambia (2003) (112)
- Bacterial contamination of the small intestine is an important cause of occult malabsorption in the elderly. (1983) (109)
- The geoepidemiology of primary biliary cirrhosis. (1997) (100)
- Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis (1999) (99)
- Osteoporosis in primary biliary cirrhosis revisited (2001) (98)
- The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol dehydrogenase genotype. (1998) (94)
- INCIDENCE AND PROGNOSTIC IMPORTANCE OF JAUNDICE AFTER CARDIOPULMONARY BYPASS SURGERY (1983) (93)
- Hepatic drug metabolism and ageing. (1990) (91)
- Primary biliary cirrhosis: geographical clustering and symptomatic onset seasonality. (1983) (85)
- Other clinical studyThe natural history of nonalcoholic fatty liver: A follow-up study (1995) (84)
- Primary biliary cirrhosis. Quantitation of autoantibodies to purified mitochondrial enzymes and correlation with disease progression. (1990) (84)
- Heterozygotes for HFE mutations have no increased risk of advanced alcoholic liver disease (1998) (83)
- Metabolic bone disease in primary biliary cirrhosis at presentation. (1988) (80)
- The effect of age on pathways of drug metabolism in human liver. (1984) (78)
- Who are the frail elderly? (1988) (73)
- T‐cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis (1995) (72)
- Are transient environmental agents involved in the cause of primary biliary cirrhosis? Evidence from space–time clustering analysis (2009) (72)
- Symptom development and prognosis in primary biliary cirrhosis: a study in two centers. (1990) (70)
- Reduction in incidence of severe paracetamol poisoning (2000) (70)
- Cancer risk in primary biliary cirrhosis: a study in northern England (1999) (70)
- Pain as a complication of use of opiate antagonists for symptom control in cholestasis. (2003) (67)
- Tumour necrosis factor-a promoter polymorphisms in primary biliary cirrhosis (1999) (64)
- A study of nutritional deficits of long-stay geriatric patients. (1993) (63)
- Primary biliary cirrhosis: contribution of HLA class II allele DR8. (1993) (62)
- HLA-DR antigens in primary biliary cirrhosis: lack of association. (1985) (61)
- Laxative-induced Diarrhoea: A Continuing Clinical Problem (1974) (60)
- The E1 alpha and beta subunits of the pyruvate dehydrogenase complex are M2'd' and M2'e' autoantigens in primary biliary cirrhosis. (1989) (60)
- Autoimmune hepatitis in older patients. (1997) (59)
- Hepatic drug clearance: the effect of age using indocyanine green as a model compound. (1990) (56)
- Drugs and the ageing liver. (1985) (56)
- The Adherent Gastric Antral and Duodenal Mucus Gel Layer Thins with Advancing Age in Subjects Infected with Helicobacter pylori (2000) (55)
- Helicobacter pylori in vivo causes structural changes in the adherent gastric mucus layer but barrier thickness is not compromised (1998) (54)
- OCCUPATIONAL VITILIGO INDUCED BY p-tert-BUTYLPHENOL, A SYSTEMIC DISEASE? (1977) (53)
- D-penicillamine for primary biliary cirrhosis. (1985) (51)
- No Rise in Incidence but Geographical Heterogeneity in the Occurrence of Primary Biliary Cirrhosis in North East England (2014) (50)
- Prospective study of post-transfusion hepatitis after cardiac surgery in a British centre. (1983) (48)
- C ASE R EPORT: Oral antioxidant therapy for the treatment of primary biliary cirrhosis: A pilot study (1999) (46)
- Clinical features and prognosis of alcoholic liver disease in respect of advancing age. (1987) (45)
- Grip strength and subjective fatigue in patients with primary biliary cirrhosis. (2001) (45)
- Ageing and duodenal morphometry. (1992) (45)
- Platelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia? (1985) (43)
- Gastrointestinal responses to oats consumption in young adult and elderly rats: digestion, large bowel fermentation and crypt cell proliferation rates (1993) (43)
- Ursodeoxycholic acid treatment for chronic cholestatic liver disease. (1990) (41)
- Reduced serum lipoprotein(a) levels in patients with primary biliary cirrhosis. (1994) (41)
- Lentil-lectin-reactive alpha-fetoprotein in the differential diagnosis of benign and malignant liver disease. (1986) (40)
- Identification and characterization of four M2 mitochondrial autoantigens in primary biliary cirrhosis. (1989) (40)
- Induction of remission in hepatocellular carcinoma with a new thymidylate synthase inhibitor, CB3717. A phase II study. (1987) (38)
- Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis. (2007) (37)
- No specific association between primary biliary cirrhosis and bacteriuria? (1989) (36)
- M4 and M9 autoantigens in primary biliary cirrhosis--a negative study. (1993) (35)
- Hepatitis C virus infection in the elderly. (1996) (35)
- Mitochondrial involvement in the ageing process. Facts and controversies (1997) (34)
- Alcohol dehydrogenase polymorphisms and predisposition to alcoholic cirrhosis (1993) (33)
- Assessing quality of life in primary biliary cirrhosis. (2004) (33)
- Low prevalence of antibody to hepatitis C virus in North East England (1990) (33)
- Primary biliary cirrhosis: epidemiology helping the clinician (1996) (32)
- Parenchymal liver disease in the elderly (1997) (32)
- Non-parenchymal cell responses in paracetamol (acetaminophen)-induced liver injury. (1994) (32)
- The effect of age and frailty upon acetanilide clearance in man. (1989) (31)
- Tamoxifen: a novel treatment for primary biliary cirrhosis? (2004) (31)
- Presentation and mortality of primary biliary cirrhosis in older patients. (2000) (28)
- A biphasic illness associated with acute hepatitis A virus infection. (1986) (28)
- Human pyruvate dehydrogenase complex as an autoantigen in primary biliary cirrhosis. (1993) (27)
- Analysis of H LA-class-li-encoded antigen-processing genes TAP1 and TAP2 in primary biliary cirrhosis (1994) (26)
- Tumour necrosis factor-alpha promoter polymorphisms in primary biliary cirrhosis. (1999) (24)
- Liver in metabolic diseases (1984) (24)
- Transjugular intrahepatic portosystemic shunt: a limited role in refractory ascites (1997) (23)
- Is measurement of type III procollagen amino propeptide useful in primary biliary cirrhosis? (1989) (23)
- Defining the immunogenetic susceptibility to primary biliary cirrhosis (1994) (23)
- Duodenal brush-border mucosal glucose transport and enzyme activities in aging man and effect of bacterial contamination of the small intestine (1993) (22)
- The association of age with the activity of alcohol dehydrogenase in human liver. (1992) (22)
- Primary biliary cirrhosis: clinical and associated autoimmune features and natural history. (1998) (22)
- Gastrointestinal and liver function of old age. (1983) (21)
- Metastatic breast carcinoma presenting as acute liver failure and portal hypertension (2002) (21)
- A trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis (2002) (21)
- The effect of age on mono-oxygenase enzyme kinetics in rat liver microsomes. (1987) (20)
- Portal hypertension secondary to arterio-portal fistulae: two unusual cases. (1999) (20)
- The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver. (1983) (20)
- Ranitidine increases the bioavailability of postprandial ethanol by the reduction of first pass metabolism. (1995) (20)
- A disease of emerging identity and importance (1998) (18)
- Liver disease in the elderly. (1994) (18)
- Is primary biliary cirrhosis a different disease in the elderly? (1985) (18)
- Sequential coronary artery bypass grafting and orthotopic liver transplantation: a case report. (1996) (17)
- The failing malignant liver (1998) (15)
- Age and the metabolism of drugs. (1987) (14)
- Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717. (1986) (14)
- Epidemiology and genetics of primary biliary cirrhosis. (1990) (14)
- No evidence for involvement of type 1 collagen structural genes in 'genetic predisposition' to alcoholic cirrhosis. (1992) (12)
- Aspects of nutrition in the elderly. (1985) (12)
- Progression of autoimmune damage in primary biliary cirrhosis: an immunohistochemical study. (1989) (11)
- Paraproteins in primary biliary cirrhosis. (1986) (11)
- Lymphocytes from patients with primary biliary cirrhosis spontaneously secrete high levels of IgG3 in culture. (1988) (11)
- Clarification of the identity of the major M2 autoantigen in primary biliary cirrhosis. (1991) (10)
- Polymerase chain reaction for detection of the alpha-1-antitrypsin Z allele in chronic liver disease. (1990) (10)
- The Canadian multi-center double-blind randomized controlled trial of ursodeoxycholic acid in primary biliary cirrhosis: Heathcote EJ, Cauch-Duder K, Walker V, Bailey RJ, Blendis LM, Ghent CM, Michieletti P, et al. Hepatology 1994;19:1149–1156 (1995) (10)
- The Diurnal Profile of Gastric Pepsin Activity Is Reduced with Helicobacter pylori Infection (2004) (10)
- Re-evaluation of the metabolism of carbocisteine in a British white population. (1993) (9)
- Unsuspected giardiasis as a cause of malnutrition and diarrhoea in the elderly. (1986) (9)
- The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease. (1985) (9)
- The Lipoate‐Containing Domain of PDC E2 Contains the Main Immunogenic Region of the 70‐kDa M2 Autoantigen in Primary Biliary Cirrhosis (1989) (9)
- Positive Antimitochondrial Antibody, Normal Liver Function Tests: Is this Primary Biliary Cirrhosis? (1985) (9)
- The Effect of Alcoholic Cirrhosis on the Two Kinetic Components (High and Low Affinity) of the Microsomal O-Deethylation of 7-Ethoxycoumarin in Human Liver (1984) (8)
- Other clinical studyT-cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis☆ (1995) (8)
- The acute and subchronic effects of ketoconazole on hepatic microsomal monooxygenases in the rat. (1988) (8)
- Hepatocellular carcinoma in north-east England: importance of hepatitis B infection and ex-tropical military service. (1986) (7)
- The effect of alcoholic cirrhosis on the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin in human liver (2004) (7)
- The value of tumour marker kinetics in the management of patients with primary hepatocellular carcinoma (1988) (7)
- Dextropropoxyphene induced hepatotoxicity mimicking biliary tract disease. (1986) (7)
- Plasma membrane form of phosphatidate phosphohydrolase: a possible role in signal transduction during liver fibrogenesis. (1993) (6)
- The relation of age to the acute effects of ethanol on acetanilide disposition. (1989) (6)
- Osteoporosis is not a specific complication of primary biliary cirrhosis (PBC) (2000) (6)
- Liver function and structure in survivors of acetaminophen poisoning (1977) (6)
- M2 AUTOANTIGENS IN PRIMARY BILIARY CIRRHOSIS (1989) (5)
- The acute effects of ethanol on acetanilide disposition in normal subjects, and in patients with liver disease. (1982) (5)
- Double blind placebo-controlled trial of prednisolone treatment in primary biliary cirrhosis (PBC): A 3 year update (1989) (5)
- Genetic evidence supporting the two-hit model of NASH pathogenesis (2002) (5)
- Pure alcoholic fatty liver and progression to cirrhosis or fibrosis (1995) (5)
- Prospective comparison of three non-invasive tests for pancreatic disease. (1984) (4)
- Plasma renin activity during the development of paracetamol (acetaminophen) induced acute renal failure in man. (1979) (3)
- Alpha 1-antitrypsin granules in the liver--always important? (1990) (3)
- Analysis of HLA-class-II-encoded antigen-processing genes TAP1 and TAP2 in primary biliary cirrhosis. (1994) (3)
- The occurence and significance of microaggregates in stored blood (2004) (3)
- Is the revised international autoimmune hepatitis group (IAHG) scoring system useful (2001) (2)
- Post-transfusion hepatitis after cardiac surgery (1984) (2)
- Flumecinol improves pruritus in cholestatic liver disease — A double blind placebo controlled trial (1990) (2)
- 2,5-Diphenyloxazole as a probe for microsomal mono-oxygenation in human and rat liver. (1985) (2)
- A population based study of autoimmunity in primary biliary cirrhosis (PBC) patients and their families: evidence for a shared susceptibility (2001) (2)
- Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis (1999) (2)
- NASH/NAFLD management. (2002) (2)
- Does primary biliary cirrhosis cluster in time? (2015) (2)
- Restrictions in the availability of paracetamol have been associated with a sustained reduction in the incidence of paracetamol hepatotoxicity (2001) (2)
- Steatohepatitis (NASH and ASH) (2001) (2)
- Aging and the Gastrointestinal Tract. (2004) (1)
- Alpha-1-antitrypsin genotype — A risk factor for alcoholic cirrhosis? (1991) (1)
- Vasculitis in primary biliary cirrhosis--response to prednisolone. (1990) (1)
- Primary hepatocellular cancer (1987) (1)
- Hepatology: A Textbook of Liver Disease: David Zakim, Thomas D. Boyer, editors; 4th ed.; Elsevier Science; GBP 230.00; ISBN: 0-7216-9051-3; 2003 (2003) (1)
- Is Ketogenesis Impaired in Patients with Hepatic Cirrhosis (1983) (1)
- Vitamin D receptor (VDR) TaqI polymorphism in primary biliary cirrhosis (PBC) (2001) (1)
- The effect of drinking behaviour on quality of life in patients with established alcoholic liver disease (2002) (1)
- Serial serum AFP heterogeneity changes in patients with hepatocellular carcinoma during chemotherapy (2004) (1)
- The Role of Renin in Acute Tubular Necrosis following Paracetamol (Ace-Taminophin) Overdose in Man (1976) (1)
- Genetic susceptibility to primary biliary cirrhosis (PBC): Analysis of chemokine receptor 5 (CCR5) delta32 deletion (2001) (1)
- Caspase 8 gene polymorphism is associated with primary biliary cirrhosis (2002) (1)
- Iron content of alcoholic fatty liver does not predict progression to fibrotic disease (1998) (0)
- Autoimmune hepatitis (AIH): Clinical spectrum of disease defined by revised international autoimmune hepatitis group (IAHG) scoring system (2002) (0)
- A placebo controlled randomised crossover trial of oral antioxidant supplementation for fatigue in primary biliary cirrhosis (PBC) (2002) (0)
- Pain as a complication of opiate antagonist therapy in cholestasis: A single centre experience (2002) (0)
- No Support from Complement Profiles Including in Vivo C3 Activation for Immune Complex Aetiology in the Pathogenesis of Primary Biliary Cirrhosis (1981) (0)
- The aging gut: pathophysiology, diagnosis and management (1984) (0)
- Case reportMetastatic breast carcinoma presenting as acute liver failure and portal hypertension (2002) (0)
- Mono oxygenase enzyme kinetics in rat liver microsomes the effect of age (1987) (0)
- Digoxin-like factors in liver disease. (1989) (0)
- Detection of the Z antitrypsin (1AT) genotype in chronic liver disease by analysis of amplified DNA sequences (1989) (0)
- Multivariate analysis of survival in a large population based cohort of patients with primary biliary cirrhosis (PBC) (2002) (0)
- 3 P Autoimmune hepatitis (AIH): Clinical spectrum of disease defined by revised international autoimmune hepatitis group (IAHG) scoring system (2002) (0)
- SEASONAL VARIATION IN THE DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS (2011) (0)
- Lipoprotein (a) [Lp(a)] levels and primary biliary cirrhosis (PBC) (1993) (0)
- Is variation in the incidence of PBC in six adjacent health districts "real" or due to variable diagnostic activity? (1999) (0)
- Regulation of the alpha-keto acid dehydrogenase complexes and their involvement in primary biliary cirrhosis. (1989) (0)
- Blood ammonia and Helicobacter pylori. (1992) (0)
- populations biliary cirrhosis in two United Kingdom control studies of risk factors for primary - Case (2010) (0)
- Natural history and demography of primary biliary cirrhosis (1998) (0)
- Carbocisteine polymorphism and disease. Author's replies (1992) (0)
- Autoimmune hepatitis (AIH), in men (2001) (0)
- NON-ALCOHOLIC STEATOHEPATITIS. AUTHORS' REPLY (1999) (0)
- Long-term survival in “modern” PBC is significantly better than the Mayo model predicts (2001) (0)
- The Use and Validation of a new QOL Scale - the PBC 40 - in Primary Biliay Cirrhosis (2005) (0)
- Prognosis of primary biliary cirrhosis (PBC) in a large unselected cohort (2000) (0)
- Terlipressin for hepatorenal impairment in alcoholic hepatitis (2000) (0)
- Evidence of Spatial variation in risk and clustering in PBC (1999) (0)
- Primary biltary cirrhosis (PBC) — A “common” disease in N.E. England (1989) (0)
- Liver Diseases in the Elderly (2008) (0)
- The burden of alcoholic liver disease (ALD) on a regional referral centre (2001) (0)
- 7-Ethoxyresorufin deethylase (EROD) in human liver —The effect of alcoholic liver disease (2006) (0)
- Selected abstracts from the meeting of the British association for the study of the liver London, U.K., 19 February, 1988 (1988) (0)
- The presentation of primary biliary cirrhosis in the elderly (1998) (0)
- Restrictions in availability of paracetamol (PAR) have been associatedwith a reduction in the incidence of par induced liver failure (2000) (0)
- Histocompatibility Antigens (Including Dr-Loci) in Primary Biliary Cirrhosis (PBC) (1983) (0)
- Regulation of human phosphatidate phosphohydrolase in human liver (1991) (0)
- Failure to sustain peripheral muscle activity as an aetiological factor for fatigue in primary biliary cirrhosis (PBC) (2001) (0)
- Kupffer Cell Phagocytosis in Relation to Bsp Clearance in Liver Disease (1978) (0)
- PBC prevalence is increasing. Geographic variations are probably “real” (1998) (0)
- 5. Bone mass and its determinants in elderly women (1990) (0)
- Bile acid sulphotransferase activity in human liver cytosol and the effect of primary biliary cirrhosis and other liver diseases (1993) (0)
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