Olaf Wolkenhauer
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German engineer
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Engineering
Olaf Wolkenhauer's Degrees
- PhD Engineering University of Rostock
- Masters Engineering University of Rostock
- Bachelors Engineering University of Rostock
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(Suggest an Edit or Addition)Olaf Wolkenhauer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Why model? (2013) (543)
- Do simple models lead to generality in ecology? (2013) (251)
- Systems medicine and integrated care to combat chronic noncommunicable diseases (2011) (230)
- Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κ B Signal Transduction Pathway (2003) (199)
- Systems Biology: the Reincarnation of Systems Theory Applied in Biology? (2001) (196)
- Fuzzy Clustering of Short Time-Series and Unevenly Distributed Sampling Points (2003) (190)
- Encyclopedia of Systems Biology (2013) (178)
- Minimum Information About a Simulation Experiment (MIASE) (2011) (150)
- Modeling and simulation of intracellular dynamics: choosing an appropriate framework (2004) (141)
- Understanding microRNA-mediated gene regulatory networks through mathematical modelling (2016) (131)
- Mathematical Modeling of the Influence of RKIP on the ERK Signaling Pathway (2003) (118)
- A systematic survey of centrality measures for protein-protein interaction networks (2017) (111)
- COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (107)
- Feedback dynamics and cell function: Why systems biology is called Systems Biology. (2005) (106)
- An introduction to systems biology (2003) (97)
- Diagnostic Potential of Imaging Flow Cytometry. (2018) (94)
- Stochastic approaches in systems biology (2011) (93)
- The road from systems biology to systems medicine (2013) (91)
- Enabling multiscale modeling in systems medicine (2014) (90)
- The dynamic systems approach to control and regulation of intracellular networks (2005) (90)
- Optimal sampling time selection for parameter estimation in dynamic pathway modeling. (2004) (85)
- Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma (2013) (85)
- Investigations Into the Analysis and Modeling of the TNFα-Mediated NF-κB-Signaling Pathway (2003) (84)
- E2F1 induces miR‐224/452 expression to drive EMT through TXNIP downregulation (2014) (81)
- Cooperative gene regulation by microRNA pairs and their identification using a computational workflow (2014) (80)
- Data engineering - fuzzy mathematics in systems theory and data analysis (2001) (78)
- miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy (2014) (77)
- Power-law models of signal transduction pathways. (2007) (76)
- MicroRNA–mRNA interactions in colorectal cancer and their role in tumor progression (2015) (76)
- Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease (2012) (74)
- Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs (2012) (74)
- Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures (2017) (72)
- Evolution of Centrality Measurements for the Detection of Essential Proteins in Biological Networks (2016) (67)
- Gene Expression in Low- and High-Dose-Irradiated Human Peripheral Blood Lymphocytes: Possible Applications for Biodosimetry (2012) (67)
- A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture (2011) (66)
- The Atlas of Inflammation Resolution (AIR) (2020) (65)
- Level sets and minimum volume sets of probability density functions (2003) (64)
- The search for organizing principles as a cure against reductionism in systems medicine (2013) (64)
- Analysis and modelling of signal transduction pathways in systems biology. (2003) (63)
- MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology. (2013) (62)
- A systems- and signal-oriented approach to intracellular dynamics. (2005) (58)
- Cardiac Function Improvement and Bone Marrow Response – (2017) (58)
- Analysing the impact of nucleo-cytoplasmic shuttling of β-catenin and its antagonists APC, Axin and GSK3 on Wnt/β-catenin signalling. (2013) (56)
- MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance (2018) (55)
- Intracellular delay limits cyclic changes in gene expression. (2006) (55)
- Microarray data clustering based on temporal variation: FCV with TSD preclustering. (2003) (54)
- Dynamics of biological systems: role of systems biology in medical research (2006) (54)
- Label‐Free Identification of White Blood Cells Using Machine Learning (2019) (53)
- Systems biology of JAK-STAT signalling in human malignancies. (2011) (53)
- Whither systems medicine? (2018) (50)
- LoRAS: an oversampling approach for imbalanced datasets (2019) (49)
- An abstract cell model that describes the self-organization of cell function in living systems. (2007) (48)
- Combining computational models, semantic annotations and simulation experiments in a graph database (2015) (48)
- Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network. (2013) (48)
- A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway (2008) (47)
- Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity (2006) (46)
- Approximations and their consequences for dynamic modelling of signal transduction pathways. (2007) (46)
- The systems biology of mitochondrial fission and fusion and implications for disease and aging (2014) (46)
- System approaches of Weiss and Bertalanffy and their relevance for systems biology today. (2011) (45)
- The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells (2010) (44)
- Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease. (2008) (43)
- SysBioMed report: advancing systems biology for medical applications. (2009) (43)
- Deterministic modelling and stochastic simulation of biochemical pathways using MATLAB. (2006) (43)
- LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1 (2020) (43)
- MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression (2016) (43)
- Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008) (2009) (43)
- Harmonizing semantic annotations for computational models in biology (2018) (42)
- TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation (2016) (42)
- How Modeling Standards, Software, and Initiatives Support Reproducibility in Systems Biology and Systems Medicine (2016) (41)
- Objective assessment of stored blood quality by deep learning (2020) (41)
- Mathematical modelling of interferon-gamma signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity. (2010) (41)
- Dynamic energy budget approaches for modelling organismal ageing (2010) (41)
- A frequency-based gene selection method to identify robust biomarkers for radiation dose prediction (2012) (40)
- Clustering of unevenly sampled gene expression time-series data (2005) (40)
- Investigating the two-moment characterisation of subcellular biochemical networks. (2008) (39)
- The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy (2017) (39)
- Mammalian γ2 AMPK regulates intrinsic heart rate (2017) (38)
- Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. (2010) (37)
- Modeling the Calvin-Benson cycle (2011) (36)
- Glucose de‐repression by yeast AMP‐activated protein kinase SNF1 is controlled via at least two independent steps (2014) (36)
- Mathematical modelling in the post-genome era: understanding genome expression and regulation--a system theoretic approach. (2002) (36)
- Association of RHAMM with E2F1 promotes tumour cell extravasation by transcriptional up‐regulation of fibronectin (2014) (36)
- Reduction of nonlinear dynamic systems with an application to signal transduction pathways. (2007) (35)
- Random-sets: theory and applications (2001) (35)
- Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures (2015) (35)
- Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells. (2015) (35)
- A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures (2013) (35)
- Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway. (2003) (35)
- Possibility theory with applications to data analysis (1998) (34)
- Family tree of Markov models in systems biology. (2006) (34)
- A Systems' Biology Approach to Study MicroRNA-Mediated Gene Regulatory Networks (2013) (34)
- Improving the reuse of computational models through version control (2013) (34)
- A system biology approach to understand functional activity of cell communication systems. (2008) (31)
- (Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach (2017) (31)
- Integrative modelling of pH-dependent enzyme activity and transcriptomic regulation of the acetone–butanol–ethanol fermentation of Clostridium acetobutylicum in continuous culture (2013) (31)
- Dynamic properties of a delayed protein cross talk model (2008) (31)
- Label‐Free Leukemia Monitoring by Computer Vision (2020) (31)
- MicroRNA Cancer Regulation (2013) (31)
- Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase. (2011) (30)
- 2‐DE profiling of GDNF overexpression‐related proteome changes in differentiating ST14A rat progenitor cells (2007) (30)
- Analysis of DNA microarray data. (2004) (29)
- Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans (2010) (29)
- Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic. (2014) (29)
- Modeling miRNA regulation in cancer signaling systems: miR-34a regulation of the p53/Sirt1 signaling module. (2012) (28)
- The Atlas of Inflammation-Resolution (AIR) (2020) (28)
- Single-Nucleus Sequencing of an Entire Mammalian Heart: Cell Type Composition and Velocity (2020) (28)
- Systems biology: Looking at opportunities and challenges in applying systems theory to molecular and cell biology (2003) (28)
- Principal difference between stability and structural stability (robustness) as used in systems biology. (2007) (27)
- Tracing organizing principles: learning from the history of systems biology. (2013) (27)
- A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus‐response experimental data (2005) (27)
- Cardiac Cell Therapies for the Treatment of Acute Myocardial Infarction: A Meta-Analysis from Mouse Studies (2017) (26)
- Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression. (2019) (26)
- A hybrid systems framework for cellular processes. (2005) (26)
- Naïve Bayes classifier predicts functional microRNA target interactions in colorectal cancer. (2015) (25)
- Systems Epidemiology: What’s in a Name? (2014) (25)
- Diagrams as locality aids for explanation and model construction in cell biology (2012) (24)
- COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms (2021) (24)
- Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models. (2010) (24)
- An algorithm to detect and communicate the differences in computational models describing biological systems (2015) (24)
- Comprehensive functional enrichment analysis of male infertility (2017) (23)
- Systems biology to battle vascular disease. (2010) (23)
- Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach (2011) (23)
- Bioinformatic assessment of mass spectrometric chemical derivatisation techniques for proteome database searching (2001) (22)
- Parameter Identifiability and Sensitivity Analysis Predict Targets for Enhancement of STAT1 Activity in Pancreatic Cancer and Stellate Cells (2012) (22)
- Information-theoretic analysis of protein sequences shows that amino acids self-cluster. (2002) (22)
- Control and coordination in biochemical networks - Introduction to the special section on systems biology (2004) (22)
- The role of theorem proving in systems biology. (2012) (21)
- A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis (2009) (21)
- Essay: Defining Systems Biology: An Engineering Perspective (2007) (21)
- Non-coding RNA detection methods combined to improve usability, reproducibility and precision (2010) (21)
- Integration of sensitivity and bifurcation analysis to detect critical processes in a model combining signalling and cell population dynamics (2010) (20)
- Tumors as chaotic attractors. (2014) (20)
- Personalized cancer immunotherapy using Systems Medicine approaches (2016) (20)
- Control and coordination in biochemical networks (2004) (19)
- Integration in action (2012) (19)
- Web resources for microRNA research. (2013) (19)
- A plea for more theory in molecular biology. (2007) (19)
- Annotation-based feature extraction from sets of SBML models (2014) (18)
- Systems biology (2003) (18)
- The role of microRNAs in the resistance to colorectal cancer treatments. (2015) (18)
- Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach. (2012) (18)
- The RNA world in the 21st century - a systems approach to finding non-coding keys to clinical questions (2016) (18)
- Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach. (2012) (17)
- Coordination of crosstalk between MAPK-PKC pathways: an exploratory study. (2007) (17)
- Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice (2020) (17)
- Phosphoglycerate Mutases Function as Reverse Regulated Isoenzymes in Synechococcus elongatus PCC 7942 (2013) (17)
- Dynamical effects of epigenetic silencing of 14-3-3sigma expression. (2009) (17)
- Systems approach to the study of brain damage in the very preterm newborn (2015) (17)
- Age-Dependent Effects of UCP2 Deficiency on Experimental Acute Pancreatitis in Mice (2014) (17)
- Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum—evidence from a mathematical model (2014) (17)
- Unveiling network-based functional features through integration of gene expression into protein networks. (2018) (17)
- Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching (2014) (17)
- MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools (2013) (17)
- Nucleo-cytoplasmic shuttling of APC can maximize β-catenin/TCF concentration. (2011) (16)
- A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy. (2018) (16)
- A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks (2011) (16)
- How mathematical modelling elucidates signalling in Bacillus subtilis (2010) (16)
- Multi-compartmental modeling of SORLA’s influence on amyloidogenic processing in Alzheimer’s disease (2012) (16)
- Considerations of graph-based concepts to manage of computational biology models and associated simulations (2012) (15)
- Random set system identification (2002) (15)
- Role of inhibitory proteins as modulators of oscillations in NFB signalling. (2009) (15)
- Interpreting Rosen (2007) (15)
- COMODI: an ontology to characterise differences in versions of computational models in biology (2016) (14)
- A fully Bayesian model to cluster gene-expression profiles (2005) (14)
- Defining systems biology: an engineering perspective. (2007) (14)
- A mathematical analysis of nuclear intensity dynamics for Mig1-GFP under consideration of bleaching effects and background noise in Saccharomyces cerevisiae. (2011) (14)
- Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis (2004) (14)
- Explanation and Organizing Principles in Systems Biology (2015) (14)
- Customized workflow development and data modularization concepts for RNA-Sequencing and metatranscriptome experiments. (2017) (13)
- Thresholds in transient dynamics of signal transduction pathways. (2010) (13)
- The role of epigenetic modifications for the pathogenesis of Crohn's disease (2021) (12)
- All models are wrong: … some more than others (2007) (12)
- SBML export interface for the systems biology toolbox for MATLAB (2007) (12)
- Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3 (2020) (12)
- The Complexity of Cell-Biological Systems (2011) (12)
- The pH-induced Metabolic Shift from Acidogenesis to Solventogenesis in Clostridium acetobutylicum – From Experiments to Models (2013) (11)
- Reproducibility of Model-Based Results in Systems Biology (2013) (11)
- Network-Assisted Disease Classification and Biomarker Discovery. (2016) (11)
- COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (11)
- Label-free assessment of red blood cell storage lesions by deep learning (2018) (11)
- Single Nuclei Sequencing of entire Mammalian Hearts: Strain-dependent Cell Type Composition and Velocity. (2020) (11)
- The role of theory and modeling in medical research (2013) (11)
- A stem cell niche dominance theorem (2010) (11)
- Simulations of stressosome activation emphasize allosteric interactions between RsbR and RsbT (2013) (11)
- Autocrine TGF-β/ZEB/microRNA-200 signal transduction drives epithelial-mesenchymal transition: Kinetic models predict minimal drug dose to inhibit metastasis. (2016) (11)
- The role of dynamic stimulation pattern in the analysis of bistable intracellular networks (2008) (10)
- Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers (2019) (10)
- Model-based investigation of the transcriptional activity of p53 and its feedback loop regulation via 14-3-3σ. (2011) (10)
- Dynamics of receptor and protein transducer homodimerisation (2008) (10)
- The Curse of Normalization (2002) (10)
- The Quest for System-Theoretical Medicine in the COVID-19 Era (2021) (9)
- Dynamics of a miRNA Model with Two Delays (2012) (9)
- Workflow Development for the Functional Characterization of ncRNAs. (2019) (9)
- Mathematical analysis of the influence of brain metabolism on the BOLD signal in Alzheimer’s disease (2017) (9)
- Systems biology approaches in aging research. (2015) (9)
- A Critique of Fuzzy Logic in Control (1997) (9)
- Exploring the Metabolic Heterogeneity of Cancers: A Benchmark Study of Context-Specific Models (2021) (9)
- Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis. (2012) (8)
- Possibilistic Testing of Distribution Functions for Change Detection (1997) (8)
- Nonlinear modelling of curvature by bi-linear metamodelling (2012) (8)
- COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms (2021) (8)
- Are all models wrong? (2020) (8)
- Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease (2022) (8)
- Fuzzy clustering and classification for automated leak detection systems (2002) (8)
- How quantitative measures unravel design principles in multi-stage phosphorylation cascades. (2008) (8)
- Book Review: A Course in Fuzzy Systems and Control: (1997) (7)
- Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (7)
- RNA-Based Strategies for Cardiac Reprogramming of Human Mesenchymal Stromal Cells (2020) (7)
- Combining computational models, semantic annotations, and associated simulation experiments in a graph database (2014) (7)
- Modelling gene expression time-series with radial basis function neural networks (2004) (7)
- Mathematical Tools in Cancer Signalling Systems Biology (2011) (7)
- Deciphering hallmark processes of aging from interaction networks. (2016) (7)
- Stochastic Modeling for Systems Biology edited by D. J. Wilkinson (2007) (6)
- Quick tips for creating effective and impactful biological pathways using the Systems Biology Graphical Notation (2018) (6)
- Reduced Adolescent-Age Spatial Learning Ability Associated with Elevated Juvenile-Age Superoxide Levels in Complex I Mouse Mutants (2015) (6)
- PLMaddon: a power-law module for the MatlabTM SBToolbox (2007) (6)
- Self-Attention-Based Models for the Extraction of Molecular Interactions from Biological Texts (2021) (6)
- Mathematical modelling unravels regulatory mechanisms of interferon-γ-induced STAT1 serine-phosphorylation and MUC4 expression in pancreatic cancer cells. (2012) (6)
- A Metabolic Model of Intestinal Secretions: The Link between Human Microbiota and Colorectal Cancer Progression (2021) (6)
- Identifying frequent patterns in biochemical reaction networks: a workflow (2018) (6)
- A Network-Based Integrative Workflow to Unravel Mechanisms Underlying Disease Progression. (2018) (6)
- Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains. (2011) (6)
- Identification of Antineoplastic Targets with Systems Approaches, Using Resveratrol as an In-Depth Case Study. (2017) (6)
- Cardiomyocyte Transplantation after Myocardial Infarction Alters the Immune Response in the Heart (2020) (6)
- Encyclopedia of Systems Biology, Vol. X (2013) (5)
- Evolution of computational models in BioModels Database and the Physiome Model Repository (2018) (5)
- Annotation-based feature extraction from sets of SBML models (2015) (5)
- Essays In Biochemistry: 45 (2008) (5)
- Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer (2021) (5)
- On the role of data, statistics and decisions in a pandemic (2021) (5)
- An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma (2020) (5)
- Systems biology and pediatric research (2013) (5)
- Mathematical Systems Biology: Genomic Cybernetics (2004) (5)
- The statistical distribution of the intensity of pixels within spots of DNA microarrays: what is the appropriate single-value representative? (2003) (5)
- Integrative workflows for network analysis. (2018) (5)
- Possibilities for Integrating Model-related Data in Computational Biology (2013) (5)
- Chaos in a delayed protein cross talk model with periodic forcing (2007) (4)
- Anti-inflammatory effects of reactive oxygen species – a multi-valued logical model validated by formal concept analysis (2014) (4)
- Somatic mutations in CTCF zinc fingers produce cellular phenotypes explained by structure-function relationships (2021) (4)
- A stem cell niche dominance theorem. (2010) (4)
- Qualitative Uncertainty Models from Random Set Theory (1997) (4)
- Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps (2021) (4)
- Label-Free Analyses of Minimal Residual Disease in ALL Using Deep Learning and Imaging Flow Cytometry (2017) (4)
- Dynamic systems reliability evaluation using uncertainty techniques for performance monitoring (1997) (4)
- Selection of most relevant centrality measures: A systematic survey on protein-protein interaction networks (2017) (4)
- Fibroblast Growth Factor 21 as a Potential Biomarker for Improved Locomotion and Olfaction Detection Ability after Weight Reduction in Obese Mice (2021) (4)
- Reverse Engineering of Biochemical Reaction Networks Using Co-evolution with Eng-Genes (2013) (4)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight (2020) (4)
- Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach (2022) (4)
- A general derivation of the differential Chapman-Kolmogorov equation (2006) (4)
- Model-Based Phenotypic Signatures Governing the Dynamics of the Stem and Semi-differentiated Cell Populations in Dysplastic Colonic Crypts (2018) (4)
- A systems biology approach to analyse amplification in the JAK 2-STAT 5 signalling pathway (2008) (4)
- Modeling Colorectal Cancer: A Stability Analysis Approach (2013) (4)
- A benchmark of hemoglobin blocking during library preparation for mRNA-Sequencing of human blood samples (2020) (3)
- Time Delay and Epo Dose Modulation in a Multilevel Model for Erythropoiesis (2009) (3)
- A system-theoretic modeling framework for cellular processes (2004) (3)
- Impact of graphene-based nanomaterials (GBNMs) on the structural and functional conformations of hepcidin peptide (2018) (3)
- Identification and epidemiological characterization of Type-2 diabetes sub-population using an unsupervised machine learning approach (2022) (3)
- Driver identification of the ras/raf/mek/erk signal transduction pathway (2005) (3)
- Automated annotation of rare-cell types from single-cell RNA-sequencing data through synthetic oversampling (2021) (3)
- Random sets and histograms (2001) (3)
- A Multi-Schematic Classifier-Independent Oversampling Approach for Imbalanced Datasets (2021) (3)
- Systems and Control Theory for Medical Systems Biology (2009) (3)
- A Study of the Statistical Distribution of the Intensity of Pixels within Spots of DNA Microarrays : What is the Appropriate Single-Valued Representative ? (2003) (3)
- Fuzzy Systems Toolbox for use with MATLAB and SIMULINK (1999) (3)
- A Graphical Users Interface to Normalize Microarray Data (2003) (3)
- Exploration of homodimer receptor: homodimer protein interactions (2009) (3)
- Dynamic Modelling of Microarray Time Course Data (2001) (2)
- The Prognostic and Predictive Role of Xeroderma Pigmentosum Gene Expression in Melanoma (2022) (2)
- Contribution of Synthetic Data Generation towards an Improved Patient Stratification in Palliative Care (2022) (2)
- Book Review: Fuzzy Set Theory — and its applications (1998) (2)
- Ein Beitrag zu einer Theorie lebender Zellen (A Contribution towards a Theory of Living Cells) (2008) (2)
- Systems Biology: Discovering the Dynamic Behavior of Biochemical Networks (2005) (2)
- Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischaemic stroke, with focus on (co)-morbidity and ageing/cellular senescence (SASKit): protocol for a prospective cohort study (2020) (2)
- Challenges and opportunities for system biology standards and tools in medical research (2016) (2)
- Modeling of cellular processes: methods, data, and requirements. (2011) (2)
- Towards a systems understanding of the cerebral motor circuit (2005) (2)
- Systems approaches in molecular and cell biology: making sense out of data and providing meaning to models (2009) (2)
- FUZZY RELATIONAL BIOLOGY A Factor-Space Approach to Genome Analysis (2002) (2)
- Enabling multiscale modeling in systems medicine: From reactions in cells to organ physiology (2014) (2)
- Envisioning the Application of Systems Biology in Cancer Immunology (2020) (2)
- Pushing limits by embracing complexity (2014) (2)
- Book Review: Fundamentals of Uncertainty Calculi with Applications to Fuzzy Inference (1996) (2)
- Fuzzy Inference Engines (2002) (2)
- Coordination Principles in Complex Systems Biology (2007) (2)
- Revisiting the General Concept of Network Centralities: A Propose for Centrality Analysis in Network Science (2017) (2)
- Simulation Study of the TNF alpha Mediated NF-kappa B Signaling Pathway (2003) (2)
- Information Technology in Systems Biology (Informationstechnologien in der Systembiologie) (2006) (2)
- Quantifying Properties of Cell Signaling Cascades (2009) (2)
- Dissecting Long-Term Glucose Metabolism Identifies New Susceptibility Period for Metabolic Dysfunction in Aged Mice (2015) (2)
- Interdisciplinarity as both Necessity and Hurdle for Progress in the Life Sciences (2013) (2)
- Analysis of Complex Behavior of Stem Cell Populations in Colonic Crypts (2015) (2)
- Tools for Understanding miRNA-mRNA Interactions for Reproducible RNA Analysis. (2019) (2)
- Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice. (2022) (1)
- Stochastic Modeling of Biochemical Networks (2011) (1)
- Systems pharmacology, drug disease interactions (2013) (1)
- Meeting review: Bioinformatics of biochips: Accelerating discovery in functional genomics (2013) (1)
- RNA Systems Biology for Cancer: From Diagnosis to Therapy. (2016) (1)
- Finding patterns in biochemical reaction networks (2016) (1)
- Bioinformatics and The Virtual Cell (Bioinformatik und die Virtuelle Zelle) (2006) (1)
- The role of cooperativity in a p53-miR34 dynamical mathematical model. (2020) (1)
- Vom Anfang und Ende der Systembiologie (2019) (1)
- Omics Integration Analyses Reveal the Early Evolution of Malignancy in Breast Cancer (2020) (1)
- Strategies to Investigate Signal Transduction Pathways with Mathematical Modelling (2010) (1)
- Computational Approaches in microRNA Biology (2019) (1)
- TGF-ß1 Induces Changes in the Energy Metabolism of White Adipose Tissue-Derived Human Adult Mesenchymal Stem/Stromal Cells In Vitro (2020) (1)
- Engineering approaches : what can we learn from it in Systems Biology ? (2007) (1)
- Simulating what cannot be simulated (2002) (1)
- Gene Expression Analysis in Human Peripheral Blood Lymphocytes for Biodosimetric Applications after Low and High Dose Gamma-Irradiation (2012) (1)
- Book Reviews: Fuzzy Preference Modelling and Multicriteria Decision Support: (1997) (1)
- Automated annotation of rare-cell types from single-cell RNA-sequencing data through synthetic oversampling (2021) (1)
- From Microscopes to Macroscopes: Advancing Biomedical Research Through Systems Approaches (2017) (1)
- Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum—evidence from a mathematical model (2014) (1)
- Melanoma 2.0. Skin cancer as a paradigm for emerging diagnostic technologies, computational modelling and artificial intelligence (2022) (1)
- Signal Selection in Microarray Data Analysis (2000) (1)
- Bifurcation Analysis of a Model Accounting for the 14-3-3s Signalling Compartmentalisation (2012) (1)
- A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms (2022) (1)
- AMES: Automated evaluation of sarcomere structures in cardiomyocytes (2021) (1)
- The role of microRNA regulation in the early inflammatory response: miR-146a and NF-κB signaling in lung inflammation (2013) (1)
- NaviCenta: Navigate the placenta (2021) (1)
- RADIATION-SPECIFIC GENE EXPRESSION CHANGES IN HUMAN PBL AFTER EX VIVO IRRADIATION SUITABLE FOR RADIATION BIODOSIMETRY (2011) (1)
- Systems biologists hope for a full integration of their field into cancer research. (2010) (1)
- Feedback Medicine: Control Systems Concepts in Personalised, Predictive Medicine and Combinatorial Intervention (2006) (1)
- An integrative computational framework for personalized detection of tumor epitopes in melanoma immunotherapy (2016) (1)
- Perspectives of (/memorandum for) systems thinking on COVID‐19 pandemic and pathology (2022) (1)
- From Networks to Systems to Complex Systems: A Signaling Pathway Coordination Case Study (2005) (1)
- Towards an Understanding of the Dynamics of Life (2003) (1)
- Biochemical Reaction Networks (2011) (1)
- GEMtractor: Extracting Views into Genome-scale Metabolic Models. (2020) (1)
- Cancer Systems Biology: Current Achievements in – Omics Data Analysis, Network Reconstruction and Mathematical Modelling (2014) (1)
- Modelling Molecular Processes by Individual-Based Simulations Applied to Actin Polymerisation (2011) (1)
- CTCF zinc finger mutations produce cellular phenotypes explained by structure-function relationships (2021) (0)
- Report of an EU projects workshop on systems biology held in Brussels, Belgium on 8 December 2004. (2005) (0)
- Time delay and protein modulation analysis in a model f RNA silencing (2009) (0)
- Simulation study of the TNFα mediated NFκB signaling pathway (2003) (0)
- A SYSTEMS APPROACH TO INVESTIGATE INFLAMMATION RESOLUTION BY MULTICOMPONENT MEDICINAL PRODUCT SERUM TENASCIN-C LEVELS ARE ELEVATED IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS (2022) (0)
- The 2MA Cell Cycle Model (2011) (0)
- Are there noumena? And can they be known? - A reply. (2004) (0)
- Quantitative modeling of amyloidogenic processing and its influence by SORLA/SORL1 in AlzheimerÂś disease (2011) (0)
- Revisiting the Implementation of the Network Centralities: A Survey on Protein-Protein Interaction Networks (2017) (0)
- Time-dependent Gene Expression Analysis in Human Peripheral Blood Lymphocytes for Biodosimetric Applications after Low and High Dose Gamma-Irradiation (2012) (0)
- Fundamental issues in modelling of dynamical systems with applications to biology CIGENE symposium at Averøy 16-19 . Sept (2004) (0)
- Accounting for Intrinsic and Extrinsic Randomness in Studying Cancer Cell Population Dynamics (2013) (0)
- Random‐Set Modelling and Identification (2002) (0)
- Systems pharmacology, drug-target networks (2013) (0)
- Wet-Lab Experiments and Noise (2011) (0)
- GEMtractor: Extracting Views into Genome-scale Metabolic Models (2019) (0)
- Mathematical Modelling of APP Processing as influenced by SORLA (2010) (0)
- Cross-tissue transcriptome-wide association studies of 885,176 individuals and seven diseases of the gut-brain axis identify susceptibility genes shared between schizophrenia and inflammatory bowel disease (2021) (0)
- Preface (2021) (0)
- Agent-based Simulation of Molecular Processes - An Application to Actin-polymerisation (2011) (0)
- Authors’ response: on the role of data, statistics and decisions in a pandemic (2022) (0)
- The Atlas of Inflammation Resolution (AIR). (2020) (0)
- Methods in In Silico Biology: Modeling Feedback Dynamics in Pathways (2011) (0)
- In silico investigation of molecular networks linking gastrointestinal diseases, malnutrition, and sarcopenia (2022) (0)
- Dynamic behavior determines the design strategy of metabolic regulation networks (2009) (0)
- Model-Based Phenotypic Signatures Governing the Dynamics of the Stem and Semi-differentiated Cell Populations in Dysplastic Colonic Crypts (2017) (0)
- A workflow for the creation of regulatory networks integrating miRNAs and lncRNAs associated with exposure to ionizing radiation using open source data and tools (2022) (0)
- Identifying , Interpreting , and Communicating Changes in XML-encoded Models of Biological Systems (2014) (0)
- Systembiologie (2021) (0)
- Detection and Analysis of Critical Dynamic Properties of Oligodendrocyte Differentiation (2022) (0)
- Prevalence of Non-obese Type 2 Diabetes in economically disadvantaged Indian rural populations (2020) (0)
- Quantitative modeling of amyloidogenic processing and its influence by SORLA/SORL1 in Alzheimer's disease (2011) (0)
- TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation (2016) (0)
- Hematopoietic Stem-Cell Senescence and Myocardial Repair: Coronary Artery Disease Genotype/Phenotype Analysis of Post-MI Myocardial Regeneration Response Induced by CABG/CD133+ Bone Marrow Hematopoietic Stem Cell Treatment in RCT PERFECT Phase 3 (2020) (0)
- Functional Models and Probability Density Functions (2003) (0)
- Quantitative analysis of the SNF1-pathway in Saccharomyces cerevisiae (2010) (0)
- 22 Mehrebenensysteme in der Biomedizin (2015) (0)
- Fuzzy Systems and Identification (2002) (0)
- Extending the philosophy of the general public licenses to the development of software tools in systems biology: A power- law module for the Matlab SBToolbox (2006) (0)
- An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma (2020) (0)
- Probability and Random Variables (2011) (0)
- An explicit numerical scheme to efficiently simulate molecular diffusion in environments with dynamically changing barriers (2015) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: awaiting peer review] (2020) (0)
- AB0063 A SYSTEMS APPROACH TO INVESTIGATE INFLAMMATION RESOLUTION BY MULTICOMPONENT MEDICINAL PRODUCT TR14 (2019) (0)
- Eu Projects Workshop Report on Systems Biology for the European Commission, Research Directorate General Directorate F -health Research Based upon a Workshop Held in Brussels, Belgium on 8 December 2004 Executive Summary (2005) (0)
- Hybrid Markov Processes (2011) (0)
- Notes on Schopenhauer and the Natural Sciences (2003) (0)
- A new perspective on teaching the natural exponential to engineering students (2021) (0)
- DDBJ genome resources (2013) (0)
- Propositions as Subsets of the Data Space (2002) (0)
- Book Review: Understanding Neural Networks and Fuzzy Logic: basic concepts and applications: (1996) (0)
- Two-moment characterisation of subcellular biochemical networks: when noise matters (2008) (0)
- Imagining the Future of Learning in Healthcare: The GAME 2019 #FuturistForum (2021) (0)
- Network analyses reveal new insights into the effect of multicomponent Tr14 compared to single-component diclofenac in an acute inflammation model (2023) (0)
- Book Review: Theoretical Aspects of Fuzzy Control (1996) (0)
- An Integrative Workflow to Prioritize Toxicity Initiation Events From Air-liquid-interface Exposure of Human Lung Cells to Combustion Aerosols: First Application to Emissions From a Heavy Fuel Oil or Diesel Fuel Operated Ship Engine (2021) (0)
- The 2MA Approach (2011) (0)
- On Information Fusion in the Life-Sciences (2001) (0)
- COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight (2020) (0)
- Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps (2022) (0)
- Modeling miRNA regulation in signaling networks: miR-34a regulation of the p53/Sirt1 module (2010) (0)
- iPlacenta - A PhD program to drive innovation in modelling placenta for Maternal and Fetal Health (2021) (0)
- Feedback Medicine: Working Notes on Control Systems Concepts in Personalised, Predictive Medicine and Combinatorial Intervention (2006) (0)
- Cell-Type-Specific Gene Regulatory Networks of Pro-Inflammatory and Pro-Resolving Lipid Mediator Biosynthesis in the Immune System (2023) (0)
- Comprehensive functional enrichment analysis of male infertility (2017) (0)
- Choosing an appropriate modeling framework: How deteministic are random processes? (2004) (0)
- A novel statistical approach in comparative genomics to reveal new immunogenic antigens in M. bovis (2004) (0)
- NCBI viral genomes resources (2013) (0)
- A Factor-Space Approach to Genome Analysis (2000) (0)
- An adaptable maintenance model using a fuzzy system and possibility theory (1998) (0)
- How to Synthesize an Optimized Genetic-Switching System? A System-Theoretic Approach Based on SQP (2003) (0)
- Managing Bio-Models: Model Storage, Retrieval, Ranking and Versioning (2011) (0)
- Logic-Based Modeling and Virtual Drug Screening for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-driven Melanoma Progression (2021) (0)
- Explorer Minimum Information About a Simulation Experiment ( MIASE ) (2017) (0)
- The systems biology of mitochondrial fission and fusion and implications for disease and aging (2013) (0)
- Exploring the evolution of biochemical models at the network level (2022) (0)
- A System-Theoretic Epistemology of Genomics (2000) (0)
- Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures (2017) (0)
- The Beauty of Mathematics – A Rough Sketch for a Proof (2009) (0)
- Customized workflow development and data integration concepts in Systems Medicine Workflows: Symbiosis of research and tool integration for clinical application Integrating data using a Systems Medicine approach (2017) (0)
- Reverse Engineering of Biochemical Reaction Networks Using Co-evolution with Eng-Genes (2012) (0)
- COMODI: an ontology to characterise differences in versions of computational models in biology (2016) (0)
- Diagrams as locality aids for explanation and model construction in cell biology (2012) (0)
- Accounting for randomness in measurement and sampling in studying cancer cell population dynamics. (2013) (0)
- University of Birmingham Mammalian 2 AMPK regulates intrinsic heart rate (2017) (0)
- Combining uniform manifold approximation with localized affine shadowsampling improves classification of imbalanced datasets (2021) (0)
- MATHEMATICAL MODELING OF THE PH-INDUCED METABOLIC SHIFT IN CLOSTRIDIUM ACETOBUTYLICUM (2014) (0)
- The role of epigenetic modifications for the pathogenesis of Crohn's disease (2021) (0)
- Whole genome expression analysis in human Jurkat cells after exposure to I-123-iododeoxyuridine, γ-rays and α-particles (2011) (0)
- Pathway maps enable straightforward yet customized and semi-automated yet insightful analyses of omics data (2018) (0)
- The Effects of Hypoxic Preconditioned Murine Mesenchymal Stem Cells on Post-Infarct Arrhythmias in the Mouse Model (2022) (0)
- Learning from Data: System Identification (2002) (0)
- A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures (2013) (0)
- Enabling multiscale modeling in systems medicine (2014) (0)
- Mehrebenensysteme in der Biomedizin (2015) (0)
- Book Reviews: Insights into Mobile Multimedia Communications, Neuro-Fuzzy Pattern Recognition: Methods in Soft Computing, DSP First: A Multimedia Approach, Power System Analysis, Numerical Methods with MATLAB: A Resource for Scientists and Engineers (2000) (0)
- Fuzzy Mathematics Fuzzy-Sets ,-Relations ,-Logic ,-Graphs ,-Mappings and The Extension Principle (2000) (0)
- the transformation of normal cells Integration in action (2013) (0)
- Introduction to the Special Issue on Systems Biology and Simulation (2003) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations] (2021) (0)
- Attention Retrieval Model for Entity Relation Extraction From Biological Literature (2022) (0)
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What Schools Are Affiliated With Olaf Wolkenhauer?
Olaf Wolkenhauer is affiliated with the following schools:
