Olga Vitek
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Biostatistician
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Olga Vitekmathematics Degrees
Mathematics
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#10868
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Applied Mathematics
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#496
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Statistics
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Mathematics
Olga Vitek's Degrees
- PhD Statistics University of Washington
- Masters Statistics University of Washington
- Bachelors Mathematics University of Washington
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Why Is Olga Vitek Influential?
(Suggest an Edit or Addition)According to Wikipedia, Olga Vitek is a biostatistician and computer scientist specializing in bioinformatics, proteomics, mass spectrometry, causal inference of biological function, and the development of open-source software for statistical analysis in these areas. She is a professor in the College of Science and Khoury College of Computer Sciences of Northeastern University.
Olga Vitek's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Analysis and validation of proteomic data generated by tandem mass spectrometry (2007) (665)
- MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments (2014) (653)
- Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues* (2015) (625)
- Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach* (2014) (430)
- SuperHirn – a novel tool for high resolution LC‐MS‐based peptide/protein profiling (2007) (349)
- A Coastal Cline in Sodium Accumulation in Arabidopsis thaliana Is Driven by Natural Variation of the Sodium Transporter AtHKT1;1 (2010) (334)
- Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast (2010) (302)
- The leaf ionome as a multivariable system to detect a plant's physiological status (2008) (271)
- Quantitative variability of 342 plasma proteins in a human twin population (2015) (269)
- Statistical design of quantitative mass spectrometry-based proteomic experiments. (2009) (227)
- Cardinal: an R package for statistical analysis of mass spectrometry-based imaging experiments (2015) (176)
- Reproducible and Consistent Quantification of the Saccharomyces cerevisiae Proteome by SWATH-mass spectrometry* (2015) (154)
- Protein Significance Analysis in Selected Reaction Monitoring (SRM) Measurements* (2011) (146)
- Multivariate statistical differentiation of renal cell carcinomas based on lipidomic analysis by ambient ionization imaging mass spectrometry (2010) (131)
- Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs (2012) (123)
- Dietary patterns in six European populations: results from EURALIM, a collaborative European data harmonization and information campaign (2000) (118)
- Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size (2013) (114)
- Multivariate statistical identification of human bladder carcinomas using ambient ionization imaging mass spectrometry. (2011) (107)
- Protein quantification in label-free LC-MS experiments. (2009) (96)
- A statistical model-building perspective to identification of MS/MS spectra with PeptideProphet (2012) (93)
- Obesity and other health determinants across Europe: The EURALIM Project (2000) (86)
- Screening for pressure ulcer risk in an acute care hospital: development of a brief bedside scale. (2002) (78)
- Identification and quantification of metabolites in 1H NMR spectra by Bayesian model selection (2011) (78)
- Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time. (2019) (77)
- Statistical design of experiments as a tool in mass spectrometry. (2005) (75)
- Prediction of colorectal cancer diagnosis based on circulating plasma proteins (2015) (74)
- Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows (2019) (72)
- Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation. (2003) (70)
- Developmental Changes in the Metabolic Network of Snapdragon Flowers (2012) (69)
- Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics (2008) (69)
- Automated selected reaction monitoring data analysis workflow for large-scale targeted proteomic studies (2013) (68)
- Computational Mass Spectrometry–Based Proteomics (2011) (62)
- Correlation between y-type ions observed in ion trap and triple quadrupole mass spectrometers. (2009) (55)
- Interdependence of signal processing and analysis of urine 1H NMR spectra for metabolic profiling. (2009) (54)
- High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome (2012) (52)
- MS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments* (2015) (51)
- Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring (2013) (49)
- Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication. (2018) (47)
- Non-invasive prognostic protein biomarker signatures associated with colorectal cancer (2015) (45)
- Probabilistic Segmentation of Mass Spectrometry (MS) Images Helps Select Important Ions and Characterize Confidence in the Resulting Segments* (2016) (41)
- Targeted proteomics reveals strain-specific changes in the mouse insulin and central metabolic pathways after a sustained high-fat diet (2013) (40)
- FSE/CACM Rebuttal2: Correcting A Large-Scale Study of Programming Languages and Code Quality in GitHub (2019) (39)
- On the Impact of Programming Languages on Code Quality (2019) (39)
- Targeted Proteomics of the Eicosanoid Biosynthetic Pathway Completes an Integrated Genomics-Proteomics-Metabolomics Picture of Cellular Metabolism* (2012) (38)
- ABRF Proteome Informatics Research Group (iPRG) 2015 Study: Detection of Differentially Abundant Proteins in Label-Free Quantitative LC-MS/MS Experiments. (2017) (37)
- Quantification of the compositional information provided by immonium ions on a quadrupole-time-of-flight mass spectrometer. (2008) (36)
- A framework for installable external tools in Skyline (2014) (35)
- New Guidelines for Publication of Manuscripts Describing Development and Application of Targeted Mass Spectrometry Measurements of Peptides and Proteins (2017) (35)
- MSstatsTMT: Statistical Detection of Differentially Abundant Proteins in Experiments with Isobaric Labeling and Multiple Mixtures (2020) (34)
- MassIVE.quant: a community resource of quantitative mass spectrometry-based proteomics datasets (2020) (33)
- A Bayesian Active Learning Experimental Design for Inferring Signaling Networks (2017) (29)
- Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis* (2015) (28)
- A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer* (2019) (28)
- MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments* (2017) (22)
- Getting Started in Computational Mass Spectrometry–Based Proteomics (2009) (20)
- Evaluating Pan and Zoom Timelines and Sliders (2019) (18)
- "Add to subtract": a simple method to remove complex background signals from the 1H nuclear magnetic resonance spectra of mixtures. (2012) (18)
- Sex Determination in Ceratopteris richardii Is Accompanied by Transcriptome Changes That Drive Epigenetic Reprogramming of the Young Gametophyte (2018) (18)
- Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition* (2019) (17)
- Reconsidering complete search algorithms for protein backbone NMR assignment (2005) (16)
- From Correlation to Causality: Statistical Approaches to Learning Regulatory Relationships in Large-Scale Biomolecular Investigations. (2016) (16)
- Using collective expert judgements to evaluate quality measures of mass spectrometry images (2015) (16)
- Selection of Features with Consistent Profiles Improves Relative Protein Quantification in Mass Spectrometry Experiments* (2020) (15)
- Deep multiple instance learning classifies subtissue locations in mass spectrometry images from tissue-level annotations (2020) (14)
- Inferential backbone assignment for sparse data (2006) (14)
- Protein biomarkers on tissue as imaged via MALDI mass spectrometry: A systematic approach to study the limits of detection (2016) (13)
- Nonlinear Regression Improves Accuracy of Characterization of Multiplexed Mass Spectrometric Assays * (2018) (13)
- Noise reduction in genome-wide perturbation screens using linear mixed-effect models (2011) (12)
- Model-Based Assignment and Inference of Protein Backbone Nuclear Magnetic Resonances (2004) (11)
- MSstatsQC 2.0: R/Bioconductor Package for Statistical Quality Control of Mass Spectrometry-Based Proteomics Experiments. (2018) (11)
- Differential Plasma Glycoproteome of p19ARF Skin Cancer Mouse Model Using the Corra Label-Free LC-MS Proteomics Platform (2008) (10)
- Leveraging Structured Biological Knowledge for Counterfactual Inference: A Case Study of Viral Pathogenesis (2021) (9)
- System-Wide Quantitative Proteomics of the Metabolic Syndrome in Mice: Genotypic and Dietary Effects. (2017) (9)
- Evaluation of label-free quantitative proteomics in a plant matrix: A case study of the night-to-day transition in corn leaf (2011) (8)
- MSstatsTMT: Statistical Detection of Differentially Abundant Proteins in Experiments with Isobaric Labeling and Multiple Mixtures. (2020) (7)
- Benchmarking comes of age (2019) (7)
- Unsupervised segmentation of mass spectrometric ion images characterizes morphology of tissues (2019) (7)
- Statistical design and analysis of label-free LC-MS proteomic experiments: a case study of coronary artery disease. (2011) (7)
- Targeted protein quantification using sparse reference labeling (2014) (6)
- Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs (2019) (6)
- Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response (2021) (5)
- matter: an R package for rapid prototyping with larger-than-memory datasets on disk (2017) (5)
- Spatial segmentation and feature selection for desi imaging mass spectrometry data with spatially-aware sparse clustering (2012) (5)
- Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition. (2020) (5)
- Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework (2021) (5)
- Integrating Markov processes with structural causal modeling enables counterfactual inference in complex systems (2019) (4)
- Statistical characterization of therapeutic protein modifications (2017) (4)
- A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer. (2019) (4)
- Selection of Features with Consistent Profiles Improves Relative Protein Quantification in Mass Spectrometry Experiments. (2020) (4)
- Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs (2012) (3)
- Verification of a Blood-Based Targeted Proteomics Signature for Malignant Pleural Mesothelioma (2020) (3)
- New mixture models for decoy-free false discovery rate estimation in mass spectrometry proteomics. (2020) (3)
- Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications (2022) (3)
- Title Protein Significance Analysis in Dda, Srm and Dia for Label-free or Label-based Proteomics Experiments (2017) (3)
- Functional evolution within a protein superfamily (2006) (3)
- Do-calculus enables causal reasoning with latent variable models (2021) (2)
- Statistical Inference of Peroxisome Dynamics (2018) (2)
- MSstatsPTM: Statistical Relative Quantification of Posttranslational Modifications in Bottom-Up Mass Spectrometry-Based Proteomics (2022) (2)
- Statistical elimination of spectral features with large between-run variation enhances quantitative protein-level conclusions in experiments with data-independent spectral acquisition (2015) (2)
- MSstats Version 4.0: Statistical Analyses of Quantitative Mass Spectrometry-Based Proteomic Experiments with Chromatography-Based Quantification at Scale. (2023) (1)
- sSeq: A Simple and Shrinkage Approach of Differential Expression Analysis for RNA-Seq experiments (2013) (1)
- Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring (2013) (1)
- A statistical model-building perspective to identification of MS/MS spectra with PeptideProphet (2012) (1)
- Leading a Statistical Bioinformatics Lab: It's All About Finding Balance (2013) (1)
- Abstract 2599: Proteomic Profiling of Plasma Samples in Coronary Artery Disease (2007) (1)
- iPRG-2013: Proteome Informatics Research Group Study: Using RNA-Seq Data to Refine Proteomic Data Analysis (2013) (1)
- Statistical elimination of spectral features with large between-run variation enhances quantitative protein-level conclusions in experiments with data-independent spectral acquisition (2015) (1)
- Do-calculus enables estimation of causal effects in partially observed biomolecular pathways (2021) (1)
- MSstatsShiny: A GUI for Versatile, Scalable, and Reproducible Statistical Analyses of Quantitative Proteomic Experiments. (2023) (1)
- Topology-based Hypothesis Generation on Causal Biological Networks using igraph (2013) (0)
- Computational Mass Spectrometry (Dagstuhl Seminar 13491) (2013) (0)
- iPRG 2015: Differential abundance analysis in label-free quantitative proteomics (2015) (0)
- P1.09-001 Multiplexed Biomarker Strategies Based on Targeted Proteomics for Detection of Malignant Pleural Mesothelioma in Blood (2017) (0)
- Multiplexed targeted proteomics signature for serum diagnostic of malignant pleural mesothelioma (2017) (0)
- Cardinal v3 - a versatile open source software for mass spectrometry imaging analysis (2023) (0)
- Statistical Methods and Tools for Quantitative Mass Spectrometry-based Proteomics (2012) (0)
- MA20.01 Global Quantitative Mass Spectrometry Reveals Potential Novel Actionable Targets in Thymic Epithelial Tumors (TET) (2019) (0)
- A noise-robust deep clustering of biomolecular ions improves interpretability of mass spectrometric images (2023) (0)
- High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome (2012) (0)
- Functional Evolution within a Protein Superfamily Research Article (2005) (0)
- Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework (2022) (0)
- System-wide quantitative proteomics of the metabolic syndrome in mice: genotypic and dietary effects (2016) (0)
- Spatial segmentation and feature selection for desi imaging mass spectrometry data with spatially-aware sparse clustering (2012) (0)
- Investigating usability of MSstatsQC software (2020) (0)
- Principles of Systems Biology, No. 31. (2018) (0)
- 214O Multiplexed proteomics biomarkers for malignant pleural mesothelioma detection in blood (2018) (0)
- Challenges in Large-Scale Computational Mass Spectrometry and Multiomics. (2016) (0)
- Author Correction: Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications. (2023) (0)
- Computational Mass Spectrometry (Dagstuhl Seminar 15351) (2015) (0)
- Experimental design for causal query estimation in partially observed biomolecular networks (2022) (0)
- FP05.02 An Early Detection and Prognostic Blood Biomarkers Signature for Malignant Pleural Mesothelioma Based on Targeted Proteomics (2021) (0)
- differentiationfor specific signaling pathways during intestinal Gene expression profiling of Caco-2 BBe cells suggests a (2015) (0)
- Immonium Ion Intensity is a Strong Predictor of Associated Amino Acid Presence Using an ABI QSTAR Hybrid TOF Mass Spectrometer (2002) (0)
- Assessment of uncertainty in protein backbone NMR assignments using Bayesian model averaging (2003) (0)
- Integrated-omics analysis uncovers a fundamental hypoxia-driven mechanism of breast cancer progression (2014) (0)
- Proteomics-Metabolomics Picture of Cellular Metabolism (2012) (0)
- Reply to Evens and Niedz: Multivariate ionomics models are robustly validated (2009) (0)
- Reconsidering Complete Search Algorithms for Protein (2005) (0)
- Statistical characterization of therapeutic protein modifications (2017) (0)
- Report from Dagstuhl Seminar 13491 Computational Mass Spectrometry (2014) (0)
- Proteomics of autophagy deficient macrophages reveals enhanced antimicrobial immunity via the oxidative stress response (2020) (0)
- Reviewer ' s report Title : Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer Version : 3 Date : (0)
- An inferential approach to protein backbone nuclear magnetic resonance assignment (2005) (0)
- Author response: Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response (2021) (0)
- Skyline Batch: An Intuitive User Interface for Batch Processing with Skyline (2021) (0)
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