Oliver Wrong
British medical academic
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Philosophy
Oliver Wrong's Degrees
- PhD Physiology University of Oxford
Why Is Oliver Wrong Influential?
(Suggest an Edit or Addition)According to Wikipedia, Professor Oliver Murray Wrong was an eminent academic nephrologist and one of the founders of the speciality in the United Kingdom. From a background as a "salt and water" physician, he made detailed clinical observations and scientifically imaginative connections which were the basis of numerous advances in the molecular biology of the human kidney. Wrong himself contributed to much of the molecular work after his own "retirement". He dictated amendments to his final paper during his final illness in his own teaching hospital, University College Hospital , London. Though academic in his leanings, he was a compassionate physician who established a warm rapport with patients , a link he regarded as the keystone of his research. He belonged to a generation of idealistic young doctors responsible for the establishment of the UK's National Health Service in the post-War years.
Oliver Wrong's Published Works
Published Works
- A common molecular basis for three inherited kidney stone diseases (1996) (696)
- Familial distal renal tubular acidosis is associated with mutations in the red cell anion exchanger (Band 3, AE1) gene. (1997) (346)
- Evidence in man that urinary electrolyte loss induced by pitressin is a function of water retention. (1953) (316)
- Dent's disease; a familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance. (1994) (310)
- Mutations in the chloride-bicarbonate exchanger gene AE1 cause autosomal dominant but not autosomal recessive distal renal tubular acidosis. (1998) (253)
- Glomerular protein sieving and implications for renal failure in Fanconi syndrome. (2001) (226)
- IN VIVO DIALYSIS OF FAECES AS A METHOD OF STOOL ANALYSIS. I. TECHNIQUE AND RESULTS IN NORMAL SUBJECTS. (1965) (187)
- Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells. (2000) (175)
- Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis). (1994) (157)
- Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders. (1997) (149)
- Effect of lactulose on ammonia production in a fecal incubation system. (1978) (132)
- Urinary acidification assessed by simultaneous furosemide and fludrocortisone treatment: an alternative to ammonium chloride. (2007) (129)
- The effect of lactulose, pectin, arabinogalactan and cellulose on the production of organic acids and metabolism of ammonia by intestinal bacteria in a faecal incubation system (1990) (118)
- In vivo dialysis of faeces as a method of stool analysis. IV. The organic anion component. (1969) (112)
- Utilisation of ammonia nitrogen for protein synthesis in man, and the effect of protein restriction and uraemia. (1967) (105)
- Tubular proteinuria defined by a study of Dent's (CLCN5 mutation) and other tubular diseases. (2000) (103)
- Dent's disease, a renal Fanconi syndrome with nephrocalcinosis and kidney stones, is associated with a microdeletion involving DXS255 and maps to Xp11.22. (1993) (102)
- Band 3 mutations, distal renal tubular acidosis, and Southeast Asian ovalocytosis. (2002) (96)
- OCRL1 Mutations in Dent 2 Patients Suggest a Mechanism for Phenotypic Variability (2009) (86)
- Band 3 Walton, a C-terminal deletion associated with distal renal tubular acidosis, is expressed in the red cell membrane but retained internally in kidney cells. (2002) (86)
- Treatment of osteomalacia of renal tubular acidosis by sodium bicarbonate alone. (1972) (82)
- Oliguric renal failure in the nephrotic syndrome. (1966) (76)
- Isolated hypercalciuria with mutation in CLCN5: relevance to idiopathic hypercalciuria. (2000) (73)
- Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients (2013) (73)
- Faecal ammonia and pH during lactulose administration in man: comparison with other cathartics (1972) (71)
- The large intestine: Its role in mammalian nutrition and homeostasis (1981) (68)
- The origin and fate of salivary urea and ammonia in man. (1977) (65)
- The contribution of endogenous urea to faecal ammonia in man, determined by 15N labelling of plasma urea. (1985) (64)
- Generation of ammonia from non-urea sources in a faecal incubation system. (1976) (58)
- The chemical composition of faeces in uraemia, as revealed by in-vivo faecal dialysis. (1968) (54)
- The effect of adrenal steroids on stool composition, as revealed by in vivo dialysis of faeces. (1969) (52)
- Urea and ammonia metabolism in the human large intestine (1984) (50)
- Nitrogen metabolism in the gut. (1978) (49)
- The mechanism of the osmotic adjustment of body cells as determined in vivo by the volume of distribution of a large water load. (1954) (48)
- In vivo dialysis of faeces as a method of stool analysis. II. The influence of diet. (1967) (48)
- Comparison of 2-mercaptopropionylglycine and D-penicillamine in the treatment of cystinuria. (1986) (47)
- Immune-related potassium-losing interstitial nephritis: a comparison with distal renal tubular acidosis. (1993) (40)
- Acute oliguric renal failure due to accelerated (malignant) hypertension. (1971) (40)
- Reversible renal failure in idiopathic nephrotic syndrome with minimal glomerular changes. (1968) (39)
- The interrelations of faecal ammonia, pH and bicarbonate: evidence of colonic absorption of ammonia by non-ionic diffusion. (1972) (39)
- 10 – Bacterial Metabolism of Protein and Endogenous Nitrogen Compounds (1988) (39)
- Tropical distal renal tubular acidosis: clinical and epidemiological studies in 78 patients. (2012) (38)
- In vivo dialysis of faeces as a method of stool analysis. 3. The effect of intestinal antibiotics. (1968) (36)
- Hyperaldosteronism secondary to renal ischaemia. (1962) (36)
- ACUTE RENAL FAILURE OF OBSTETRIC ORIGIN: AN ANALYSIS OF 70 PATIENTS. (1965) (32)
- KIDNEY HOMOTRANSPLANTATION IN THE HUMAN. (1963) (31)
- DOMESTIC METALLIC MERCURY POISONING (1984) (30)
- URINARY EXCRETION OF HYDROGEN ION IN PATIENTS WITH URIC ACID CALCULI. (1965) (30)
- Recessive distal renal tubular acidosis in Sarawak caused by AE1 mutations (2006) (28)
- The natural history of distal renal tubular acidosis. (1980) (27)
- The relationship between water retention and electrolyte excretion following administration of anti-diuretic hormone. (1956) (27)
- Effect of graded compression of the renal artery on water and solute excretion. (1954) (26)
- A method of obtaining faecal fluid by in-vivo dialysis. (1961) (26)
- Sevelamer and Other Anion-Exchange Resins in the Prevention and Treatment of Hyperphosphataemia in Chronic Renal Failure (2007) (24)
- Dent's disease. (2005) (23)
- The association between familial distal renal tubular acidosis and mutations in the red cell anion exchanger (band 3, AE1) gene. (1998) (23)
- The metabolism of tartrate in man and the rat. (1978) (23)
- Distal renal tubular acidosis: the value of urinary pH,PCO2 and NH4+ measurements (1991) (21)
- Sevelamer-induced acidosis. (2005) (20)
- Persistent alkalosis and hypokalaemia caused by surreptitious vomiting. (1968) (20)
- Uraemic Pericarditis With Cardiac Tamponade: A Report of Four Cases (1964) (19)
- The electrolyte content faeces. (1965) (19)
- The Effect of Lactulose on Ammonia Production in a Faecal Incubation System (1978) (18)
- The effect of oral anion exchange resins on faecal anions. Comparison with calcium salts and aluminium hydroxide. (1963) (18)
- The influence of pH, bicarbonate and hypertonicity on the absorption of ammonia from the rat intestine. (1970) (17)
- THE METABOLISM OF UREA AND AMMONIA IN THE HEALTHY AND URAEMIC COLON (1967) (16)
- Campylobacter pylori, duodenal ulcer disease, and gastrin. (1989) (16)
- URINARY EXCRETION OF HYDROGEN-ION IN ACUTE OLIGURIC RENAL FAILURE. (1964) (16)
- Incidence of Hypokalaemia in Severe Hypertension (1961) (16)
- RENAL FAILURE OF OBSTETRIC ORIGIN (1968) (14)
- Distal Renal Tubular Acidosis in Filipino Children, Caused by Mutations of the Anion-Exchanger SLC4A1 (AE1, Band 3) Gene (2010) (13)
- Aluminium resin for the treatment of the hyperkalamia of renal failure. (1968) (11)
- The volume control of body-fluids. (1957) (11)
- Nephrocalcinosis: another cause of renal erythrocytosis. (1978) (11)
- HYPERCALCÆMIA FROM CALCIUM RESIN IN PATIENTS WITH CHRONIC RENAL FAILURE (1968) (10)
- The incorporation of ammonia nitrogen into albumin in man: the effects of diet, uremia and growth hormone. (1975) (10)
- Aldosterone and electrolyte movements in the colon. (1968) (10)
- Distal Renal Tubular Acidosis: Alkali Heals Osteomalacia and Increases Net Production of 1,25-Dihydroxyvitamin D (2005) (9)
- Dominant inheritance in a family with familial renal tubular acidosis. (1972) (8)
- Renal Tubular Obstruction by Mucoproteins from Adenocarcinoma of Pancreas (1974) (8)
- Bilateral adrenal masses. (1985) (8)
- Inherited Defects in Distal Tubular Acidification (1975) (8)
- Organic Acids in Man (1982) (8)
- Action of d-aldosterone on the electrolyte composition of human cells grown in vitro. (1966) (7)
- Recovery from acute renal failure due to "irreversible" glomerular disease. (1968) (7)
- Potassium deficiency and sudden unexplained nocturnal death (1991) (7)
- Osler and my father. (2003) (7)
- Observations upon ammonia absorption from the human ileum (1973) (6)
- Book Review: Principles for the Safety Assessment of Food Additives and Contaminants in Food (1989) (6)
- Vascular lesions in malignant hypertension. (1969) (6)
- Low molecular weight ('Tubular') proteinuria in patients with mutations of the CLCN5 renal chloride channel gene (1999) (6)
- HYPERALUMINÆMIA FROM ALUMINIUM RESINS (1970) (6)
- METABOLIC PROFILE TESTING IN DAIRY HERDS: WRONG ANSWER (2007) (5)
- Cholestyramine in uraemie pruritis. (1977) (5)
- Assessment of urine-concentrating ability in man: effect of fludrocortisone and urea in enhancing response to vasopressin. (1975) (5)
- Intestinal handling of urea and ammonia. (1971) (5)
- A woman with bone pain, fractures, and malabsorption (1996) (5)
- Renal excretion of ammonia and urate production: examination of Gutman-Yü hypothesis. (1972) (4)
- Sevelamer 'carbonate': what's in a name? (2010) (4)
- A Guide to Learning Fluid Therapy (1964) (4)
- Fragmentation of filtered proteins and implications for glomerular protein sieving in Fanconi syndrome. (2002) (4)
- Urine concentration after acute renal failure. (1966) (4)
- Live E. coli cells to treat uremia (1997) (4)
- Ammonia production in the human colon. (1971) (4)
- Mutations in the chloride channel gene (CLCN5) are associated with hypercalciuric rickets and nephrolithiasis. (1996) (3)
- PSYCHIATRIC DISTURBANCE AND ELECTROLYTE DEPLETION (1968) (3)
- LACTTTOL, LACTULOSE, AND BLOOD AMMONIA (1987) (3)
- The relation between faecal pH, ammonia, and bicarbonate in man. (1972) (3)
- Hypercalcaemia from calcium resin in patients with chronic renal failure. (1968) (2)
- INVESTIGATION AND TREATMENT OF ENDOCRINOLOGICAL DISORDERS (1972) (2)
- X-linked recessive nephrolithiasis with renal failure. (1992) (2)
- Ammonia metabolism in renal failure. (1969) (2)
- Altered red cell anion exchanger (Band 3, AE1) associated with familial distal renal tubular acidosis. (1996) (2)
- DEHYDRATION FROM TUBE-FEEDING (1956) (2)
- Points: Ammonia burns of the eye (1988) (2)
- Persistent alkalosis and hypo kalemia caused by surreptitious vomiting human enz renin angiotensin cardio vasc (1968) (1)
- Response to ‘Simultaneous fludrocortisone and furosemide for assessment of urinary acidification’ (2007) (1)
- Anion-exchange resins in treatment of uraemic acidosis and hyperphosphataemia. (1973) (1)
- Osler and My Father (2003) (1)
- Lactic acidosis and the M.D. thesis. (1970) (1)
- ACID-BASE EFFECTS OF "NON-SYSTEMIC" ANTACIDS (1986) (1)
- By-Laws of the International Society of Nephrology (1964) (1)
- Renal tubular acidosis: ‘RTA is no accident’ (2012) (1)
- Erythrocytosis and nephrocalcinosis. (1992) (1)
- Sevelamer-induced acidosis. Authors' reply (2005) (1)
- Haemodialysis in Young Children (1965) (1)
- Hypercalcaemia from calcium resin. (1969) (1)
- Ammonia Generation by Incubated Faeces (1976) (1)
- Sevelamer. Authors' reply (2008) (1)
- Mutations in the band 3 (AE1) gene associated with distal renal tubular acidosis (2001) (0)
- An examiner in Sri Lanka. (1992) (0)
- Assessment of Intestinal Function with Relation to Water and Electrolyte Absorption (1971) (0)
- Proteinuria of the Fanconi syndrome comprises proteins in the mass range from insulin to IgG (2001) (0)
- Book Review: International Review of Physiology, vol 11: Kidney and Urinary Tract Physiology 2 (1977) (0)
- AMMONIA NITROGEN AND PROTEIN SYNTHESIS (1967) (0)
- A woman with bone pain, fractures, and malabsorption. (1996) (0)
- Hyperaluminaemia form aluminium resins. (1970) (0)
- Nephrology: A Review of Clinical Nephrology (1978) (0)
- Ion transport processes in distal renal tubular acidosis (dRTA) (2011) (0)
- Combined loop diuretic and mineralocorticoid treatment as a screening test for distal renal tubular acidosis (2006) (0)
- Ammonia burns of the eye. (1988) (0)
- OXFORD CLINICAL SCHOOL (1978) (0)
- Mutations of the Chloride/Proton Antiporter, CLC-5, lead to Impaired Endosomal Acidification in Human Proximal Tubule Epithelial Cell-lines (2012) (0)
- Images in Nephrology (Section Editor: Guy Neild) (2005) (0)
- Sevelamer-induced acidosis [2] (multiple letters) (2005) (0)
- Letter: Apology for "hypercalcinuria". (1975) (0)
- Renal failure in nephrotic syndrome. (1968) (0)
- Book Review: The Kidney in Pregnancy (1977) (0)
- Editorial: Inherited defects in distal tubular acidification. (1975) (0)
- THE GENE CAUSING DENTS DISEASE, A RENAL FANCONI SYNDROME WITH NEPHROCALCINOSIS AND KIDNEY-STONES, IS ON THE SHORT ARM OF THE X-CHROMOSOME (XP11.22) (1993) (0)
- Management of the acute uraemic emergency. (1971) (0)
- Book Review: Nephrology: A Review of Clinical Nephrology. (1978) (0)
- HEREDITARY NEPHROLITHIASIS IS ASSOCIATED WITH MUTATIONS IN AN X-LINKED CHLORIDE CHANNEL GENE (1995) (0)
- Sodium excretion and the control of extra-cellular fluid volume. (1958) (0)
- AE1 mutations associated with distal renal tubular acidosis (dRTA) and Southeast Asian Ovalocytosis (SAO) in Malaysia and Papua New Guinea (PNG) (2000) (0)
- Renal Tubular Acidosis, Stones, and Nephrocalcinosis (2014) (0)
- Apology for Hypercalcinuria (1975) (0)
- Clinical medicine and research in Italy. (1974) (0)
- Vocational training and specialist registration (1969) (0)
- Book Review: A Guide to Learning Fluid Therapy (1964) (0)
- Cholestyramine in uraemie pruritus. (1977) (0)
- MAPPING OF 2 HEREDITARY RENAL TUBULAR DISORDERS ASSOCIATED WITH KIDNEY-STONES, AND REFERRED TO AS DENT-DISEASE AND X-LINKED RECESSIVE NEPHROLITHIASIS, TO CHROMOSOME-XP11 (1994) (0)
- Dominantly inherited distal renal tubular acidosis (dRTA) is associated with mutations in the red cell anion exchanger (BAND 3, AE1) gene. (1997) (0)
- Self assessment questions: Renal tubular acidosis (2012) (0)
- Quantitative definition of tubular proteinuria based on studies of patients with mutations of the CLCN5 chloride channel gene (Dents disease and X-linked recessive nephrolithiasis) (1998) (0)
- Symposium: Salt and Water [Abridged] (1965) (0)
- Book Review: The Challenge of Urinary Tract Infections (1981) (0)
- Tests of renal tubular function. (1962) (0)
- Metabolic Acidosis. Ciba Foundation Symposium 87. Edited by R. Porter and G. Lawrenson. Pp. 393. (Pitman, 1982.) £25.00 (1983) (0)
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