Olivier Devuyst

Q: What Schools Are Affiliated With Olivier Devuyst

Olivier Devuyst is affiliated with the following schools: Ghent University, Université catholique de Louvain, University of Basel, Johns Hopkins University, University of Bern, University of Adelaide, University of Geneva, University of Zurich

Olivier Devuyst's AcademicInfluence.com Rankings

Olivier Devuyst

Biology

#9045

World Rank

#12202

Historical Rank

Cell Biology

#379

World Rank

#389

Historical Rank

Physiology

#261

World Rank

#462

Historical Rank

Molecular Biology

#1199

World Rank

#1225

Historical Rank

biology Degrees

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Biology

Olivier Devuyst's Degrees

PhD Biomedical Sciences University of Geneva
Masters Biochemistry University of Zurich

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Olivier Devuyst's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tolvaptan in patients with autosomal dominant polycystic kidney disease. (2012) (1190)
Evolving importance of kidney disease: from subspecialty to global health burden (2013) (909)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. (2015) (409)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Tolvaptan in Later‐Stage Autosomal Dominant Polycystic Kidney Disease (2017) (339)
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders (2015) (319)
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules (2003) (306)
NHE2 and NHE3 are human and rabbit intestinal brush-border proteins. (1996) (304)
The Current State of Peritoneal Dialysis. (2016) (299)
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression (2013) (298)
Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. (2000) (293)
Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease. (1999) (271)
Genetic loci influencing kidney function and chronic kidney disease (2010) (266)
Cubilin is essential for albumin reabsorption in the renal proximal tubule. (2010) (255)
Mutations in SEC63 cause autosomal dominant polycystic liver disease (2004) (254)
A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (252)
Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management--A KDIGO consensus report. (2015) (234)
The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease. (2011) (232)
Autosomal dominant polycystic kidney disease: the changing face of clinical management (2015) (231)
The pathophysiology of the peritoneal membrane. (2010) (223)
CUBN is a gene locus for albuminuria. (2011) (214)
Vascular proliferation and enhanced expression of endothelial nitric oxide synthase in human peritoneum exposed to long-term peritoneal dialysis. (2000) (207)
Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice (2016) (204)
A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin. (2003) (199)
Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. (2017) (198)
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (183)
Uromodulin: from physiology to rare and complex kidney disorders (2017) (180)
CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia. (2011) (178)
Spectrum of mutations in Gitelman syndrome. (2011) (176)
Regulated acid–base transport in the collecting duct (2009) (173)
Modifier effect of ENOS in autosomal dominant polycystic kidney disease. (2002) (173)
Rare inherited kidney diseases: challenges, opportunities, and perspectives (2014) (168)
A role for Rhesus factor Rhcg in renal ammonium excretion and male fertility (2008) (167)
SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule (2020) (162)
Diagnosis, management, and prognosis of HNF1B nephropathy in adulthood. (2011) (155)
Transcriptional and functional analyses of SLC12A3 mutations: new clues for the pathogenesis of Gitelman syndrome. (2007) (150)
Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. (2006) (150)
A role for CFTR in human autosomal dominant polycystic kidney disease. (1996) (148)
A New Antigen Recognized by Cytolytic T Lymphocytes on a Human Kidney Tumor Results from Reverse Strand Transcription (1999) (148)
Dent's disease (2010) (138)
Both the wild type and a functional isoform of CFTR are expressed in kidney. (1996) (137)
Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 Study. (2011) (134)
Expression of aquaporins-1 and -2 during nephrogenesis and in autosomal dominant polycystic kidney disease. (1996) (132)
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL (2016) (122)
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes (2015) (121)
Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial. (2016) (119)
Genetic and clinical factors influence the baseline permeability of the peritoneal membrane. (2005) (118)
Chronic uremia induces permeability changes, increased nitric oxide synthase expression, and structural modifications in the peritoneum. (2001) (115)
Expression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney development. (2002) (113)
A primary culture of mouse proximal tubular cells, established on collagen-coated membranes. (2007) (112)
Regulation of aquaporin-1 and nitric oxide synthase isoforms in a rat model of acute peritonitis. (1999) (109)
High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease. (2005) (106)
Multicenter, open-label, extension trial to evaluate the long-term efficacy and safety of early versus delayed treatment with tolvaptan in autosomal dominant polycystic kidney disease: the TEMPO 4:4 Trial (2017) (106)
Molecular Physiology of Water Balance. (2015) (103)
Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney (2018) (103)
The Hypertension Pandemic: An Evolutionary Perspective. (2017) (101)
Aortic Stiffness and Central Wave Reflections Predict Outcome in Renal Transplant Recipients (2011) (101)
Phenotype and outcome in hereditary tubulointerstitial nephritis secondary to UMOD mutations. (2011) (101)
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells (2007) (98)
Tamm-Horsfall protein or uromodulin: new ideas about an old molecule. (2005) (98)
Cofilin Interacts with ClC-5 and Regulates Albumin Uptake in Proximal Tubule Cell Lines* (2003) (98)
Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells. (2001) (98)
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis (2011) (96)
Progression of coronary artery calcification and thoracic aorta calcification in kidney transplant recipients. (2012) (95)
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. (2010) (94)
Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease. (2011) (93)
Comparison between siblings and twins supports a role for modifier genes in ADPKD. (2004) (93)
Cystic fibrosis is associated with a defect in apical receptor-mediated endocytosis in mouse and human kidney. (2007) (91)
Toward better dialysis compatibility: advances in the biochemistry and pathophysiology of the peritoneal membranes. (2002) (89)
Genetics of hypercalciuric stone forming diseases. (2007) (89)
Corticosteroids induce expression of aquaporin-1 and increase transcellular water transport in rat peritoneum. (2003) (88)
A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure. (2010) (88)
Aquaporin-1 and endothelial nitric oxide synthase expression in capillary endothelia of human peritoneum. (1998) (87)
Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform. (2000) (87)
Positron-emission computed tomography in cyst infection diagnosis in patients with autosomal dominant polycystic kidney disease. (2011) (86)
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria (2019) (86)
Morphological and functional changes in the dialysed peritoneal cavity: impact of more biocompatible solutions. (2002) (85)
Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients. (2003) (85)
Renal phenotype of the cystinosis mouse model is dependent upon genetic background. (2010) (85)
The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland. (2006) (83)
Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. (2014) (83)
The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2 (2017) (82)
Gitelman’s syndrome: towards genotype-phenotype correlations? (2007) (82)
Haematological changes and infectious complications in anorexia nervosa: a case-control study. (1993) (81)
The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin (2015) (79)
The triggering of human peritoneal mesothelial cell apoptosis and oncosis by glucose and glycoxydation products. (2004) (78)
Diagnosis of cyst infection in patients with autosomal dominant polycystic kidney disease: attributes and limitations of the current modalities. (2012) (77)
Expression of aquaporin-1 in a long-term peritoneal dialysis patient with impaired transcellular water transport. (1999) (76)
Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC. (2018) (76)
Autosomal dominant tubulointerstitial kidney disease (2019) (75)
Renal expression of parvalbumin is critical for NaCl handling and response to diuretics (2007) (75)
The ClC‐5 Knockout Mouse Model of Dent's Disease Has Renal Hypercalciuria and Increased Bone Turnover (2003) (74)
Developmental regulation of CFTR expression during human nephrogenesis. (1996) (74)
Deterioration in renal function associated with fibrate therapy. (2001) (74)
Determination of uromodulin in human urine: influence of storage and processing. (2014) (74)
Interstitial Fibrosis Restricts Osmotic Water Transport in Encapsulating Peritoneal Sclerosis. (2015) (72)
Water transport across the peritoneal membrane. (2014) (72)
Associations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population. (2016) (72)
Soluble klotho and autosomal dominant polycystic kidney disease. (2012) (70)
PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice. (2007) (68)
Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone. (2005) (67)
Multicenter, open-label, extension trial to evaluate the long-term efficacy and safety of early versus delayed treatment with tolvaptan in autosomal dominant polycystic kidney disease: the TEMPO 4:4 Trial. (2017) (67)
Increased protein glycation in fructosamine 3-kinase-deficient mice. (2006) (67)
Chloride channels in the kidney: lessons learned from knockout animals. (2002) (67)
Simultaneous sequencing of 37 genes identified causative mutations in the majority of children with renal tubulopathies. (2018) (64)
Dedifferentiation and aberrations of the endolysosomal compartment characterize the early stage of nephropathic cystinosis. (2014) (64)
Somatic uniparental isodisomy explains multifocality of glomuvenous malformations. (2013) (63)
Diabetes-induced microvascular dysfunction in the hydronephrotic kidney: role of nitric oxide. (2001) (63)
Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial. (2017) (62)
Serum fetuin-A levels are associated with vascular calcifications and predict cardiovascular events in renal transplant recipients. (2011) (60)
CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease (2009) (59)
Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis. (2003) (59)
Genetic variation of DKK3 may modify renal disease severity in ADPKD. (2010) (58)
Observations of a large Dent disease cohort. (2016) (58)
Anorexia nervosa: correlation between MR appearance of bone marrow and severity of disease. (1994) (58)
Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome. (2006) (58)
Renal transplantation in autosomal dominant polycystic kidney disease (2014) (57)
Osmoregulation, vasopressin, and cAMP signaling in autosomal dominant polycystic kidney disease (2013) (57)
Endocytosis of the somatostatin analogue, octreotide, by the proximal tubule-derived opossum kidney (OK) cell line. (2005) (56)
Mutation Update of the CLCN5 Gene Responsible for Dent Disease 1 (2015) (56)
Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome (2017) (56)
Architecture and function of human uromodulin filaments in urinary tract infections (2020) (56)
Transgenic Mouse Models (2007) (54)
Copeptin is associated with kidney length, renal function, and prevalence of simple cysts in a population-based study. (2015) (54)
Metabolic effects of amino acid solutions infused for renal protection during therapy with radiolabelled somatostatin analogues. (2004) (53)
Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function. (2016) (53)
Biochemical characterization of bona fide polycystin-1 in vitro and in vivo. (2001) (53)
Toward understanding renal Fanconi syndrome: step by step advances through experimental models. (2011) (52)
Prevalence of Hypertension in Children with Early-Stage ADPKD. (2018) (52)
The relation between hypomagnesaemia and vascular stiffness in renal transplant recipients. (2011) (52)
Autosomal dominant polycystic kidney disease is associated with central and nephrogenic defects in osmoregulation. (2012) (52)
AqF026 is a pharmacologic agonist of the water channel aquaporin-1. (2013) (51)
Role of RhAG and AQP1 in NH3 and CO2 gas transport in red cell ghosts: a stopped-flow analysis. (2006) (51)
Expression of CFTR in human and bovine thyroid epithelium. (1997) (50)
The UMOD Locus: Insights into the Pathogenesis and Prognosis of Kidney Disease. (2017) (50)
Inhibition of nitric oxide synthase reverses changes in peritoneal permeability in a rat model of acute peritonitis. (2001) (49)
Coronary artery calcification: a strong predictor of cardiovascular events in renal transplant recipients. (2010) (49)
Association of PKD2 (polycystin 2) mutations with left-right laterality defects. (2011) (49)
Carbohydrate antigen 19-9 as a diagnostic marker for hepatic cyst infection in autosomal dominant polycystic kidney disease. (2010) (48)
Critical Role of Aquaporins in Interleukin 1β (IL-1β)-induced Inflammation* (2014) (47)
Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. (2005) (47)
Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis. (2018) (46)
Albuminuria and tolvaptan in autosomal-dominant polycystic kidney disease: results of the TEMPO 3:4 Trial. (2016) (46)
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency (2020) (46)
Clinical and Genetic Spectra of Autosomal Dominant Tubulointerstitial Kidney Disease due to Mutations in UMOD and MUC1. (2020) (45)
CF gene and cystic fibrosis transmembrane conductance regulator expression in autosomal dominant polycystic kidney disease. (2000) (45)
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. (2017) (44)
A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction. (2008) (44)
Modified aquaporin 5 expression and distribution in submandibular glands from NOD mice displaying autoimmune exocrinopathy. (2007) (42)
Expression of the beta2-subunit and apical localization of Na+-K+-ATPase in metanephric kidney. (1999) (42)
Experimental diabetes induces functional and structural changes in the peritoneum. (2002) (42)
Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome. (2016) (41)
Learning Physiology From Inherited Kidney Disorders. (2019) (41)
Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease. (2019) (39)
Early experience with COVID-19 in kidney transplantation (2020) (39)
Tolvaptan and Kidney Pain in Patients With Autosomal Dominant Polycystic Kidney Disease: Secondary Analysis From a Randomized Controlled Trial (2016) (39)
Gating defects of a novel Na+ channel mutant causing hypokalemic periodic paralysis. (2006) (39)
A New Role for Aquaporin 7 in Insulin Secretion (2012) (38)
Chloride Channels and Endocytosis: New Insights from Dent’s Disease and ClC-5 Knockout Mice (2005) (38)
Implication of fibrate therapy for homocysteine (1999) (38)
A coherent organization of differentiation proteins is required to maintain an appropriate thyroid function in the Pendred thyroid. (2010) (37)
Creatinine rise after fibrate therapy in renal graft recipients (1993) (37)
The rhesus protein RhCG: a new perspective in ammonium transport and distal urinary acidification. (2011) (37)
Epigenetic control of aquaporin 1 expression by the amyloid precursor protein (2009) (37)
Functional and molecular characterization of a peritoneal dialysis model in the C57BL/6J mouse. (2005) (37)
Basolateral chloride transporters in autosomal dominant polycystic kidney disease (2002) (36)
Recurrent FXYD2 p.Gly41Arg mutation in patients with isolated dominant hypomagnesaemia. (2015) (36)
Uromodulin: Roles in Health and Disease. (2021) (36)
Role of caveolin-1 in thyroid phenotype, cell homeostasis, and hormone synthesis: in vivo study of caveolin-1 knockout mice. (2009) (36)
Prevalence and Determinants of Coronary and Aortic Calcifications Assessed by Chest CT in Renal Transplant Recipients (2007) (36)
Uromodulin and Nephron Mass. (2018) (36)
Prognostic Enrichment Design in Clinical Trials for Autosomal Dominant Polycystic Kidney Disease: The TEMPO 3:4 Clinical Trial (2016) (36)
Tubular Disorders of Electrolyte Regulation (2009) (36)
L-carnitine is an osmotic agent suitable for peritoneal dialysis. (2011) (35)
Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. (2016) (35)
Tolerability of Aquaretic-Related Symptoms Following Tolvaptan for Autosomal Dominant Polycystic Kidney Disease: Results From TEMPO 3:4 (2017) (35)
Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis. (2017) (35)
OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease (2018) (35)
Chloride transporters and receptor‐mediated endocytosis in the renal proximal tubule (2015) (34)
PKD1 haploinsufficiency is associated with altered vascular reactivity and abnormal calcium signaling in the mouse aorta (2009) (34)
Mechanisms of Crystalloid versus Colloid Osmosis across the Peritoneal Membrane. (2018) (34)
Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate (2014) (33)
A specific method for measurement of nitric oxide synthase enzymatic activity in peritoneal biopsies. (2000) (33)
Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. (2017) (33)
Central and extrapontine myelinolysis in a patient in spite of a careful correction of hyponatremia. (2001) (33)
The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution. (2016) (33)
CFTR and defective endocytosis: new insights in the renal phenotype of cystic fibrosis (2009) (33)
Long wavelength multiphoton excitation is advantageous for intravital kidney imaging. (2016) (33)
A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress (2017) (33)
Study of candidate genes affecting the progression of renal disease in autosomal dominant polycystic kidney disease type 1. (2007) (33)
New insights in the molecular mechanisms regulating peritoneal permeability. (2002) (33)
Nitric oxide synthase isoforms play distinct roles during acute peritonitis (2009) (32)
Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter. (2014) (32)
Single photon emission-computed tomography (SPECT) for functional investigation of the proximal tubule in conscious mice. (2010) (32)
Renal handling of zinc in chronic kidney disease patients and the role of circulating zinc levels in renal function decline. (2020) (32)
Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation (2014) (32)
Parvalbumin: calcium and magnesium buffering in the distal nephron. (2012) (32)
Haploinsufficiency of the Ammonia Transporter Rhcg Predisposes to Chronic Acidosis (2012) (31)
Can we further enrich autosomal dominant polycystic kidney disease clinical trials for rapidly progressive patients? Application of the PROPKD score in the TEMPO trial (2017) (31)
Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney (2020) (31)
Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion. (2016) (31)
Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis (2019) (30)
Glomerular and proximal tubule cysts as early manifestations of Pkd1 deletion. (2010) (30)
Autosomal dominant polycystic kidney disease: modifier genes and endothelial dysfunction. (2003) (29)
Impaired osmoregulation in anorexia nervosa: a case-control study. (2004) (29)
Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. (2004) (29)
Aquaporin-1 and endothelial nitric oxide synthase expression in capillary endothelia of human peritoneum. (1998) (28)
High-throughput sequencing contributes to the diagnosis of tubulopathies and familial hypercalcemia hypocalciuria in adults. (2019) (28)
Targeting of sodium-glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han:SPRD rats. (2013) (28)
Genome-Wide Meta-Analysis Unravels Interactions between Magnesium Homeostasis and Metabolic Phenotypes. (2017) (28)
Erratum: A role for CFTR in human autosomal dominant polycystic kidney disease (American Journal of Physiology - Cell Physiology (January 1996) 270:39 (C389-C399)) (1996) (27)
Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect* (2016) (27)
AQUAPORIN-1: NEW DEVELOPMENTS AND PERSPECTIVES FOR PERITONEAL DIALYSIS (2010) (27)
European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care (2017) (27)
Renal cyst infection in autosomal dominant polycystic kidney disease. (2007) (26)
A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing (2014) (25)
Nitric oxide is involved in interleukin-1alpha-induced cytotoxicity in polarised human thyrocytes. (2002) (25)
[Systematically Initiating Insulin: The Staged Diabetes Management Approach] (2006) (25)
Regulation of Macrophage Motility by the Water Channel Aquaporin-1: Crucial Role of M0/M2 Phenotype Switch (2015) (25)
Tubular proteinuria in patients with HNF1α mutations: HNF1α drives endocytosis in the proximal tubule. (2016) (25)
Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine (2016) (25)
Salt wasting and blood pressure (2008) (24)
A homozygous mutation in INVS causing juvenile nephronophthisis with abnormal reactivity of the Wnt/beta-catenin pathway. (2010) (24)
The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo. (2010) (23)
Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21 (2010) (23)
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide (2020) (23)
A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency. (2014) (23)
Expression patterns of the aquaporin gene family during renal development: influence of genetic variability (2009) (22)
Aquaporin‐1 in the peritoneal membrane: implications for peritoneal dialysis and endothelial cell function (2005) (22)
Bone marrow transplantation improves proximal tubule dysfunction in a mouse model of Dent disease. (2017) (22)
Multicenter Study of Long-Term Safety of Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease. (2020) (22)
Tolvaptan suppresses monocyte chemotactic protein-1 excretion in autosomal-dominant polycystic kidney disease (2016) (22)
Defects in KCNJ16 Cause a Novel Tubulopathy with Hypokalemia, Salt Wasting, Disturbed Acid-Base Homeostasis, and Sensorineural Deafness (2021) (21)
Resistance to Insulin in Patients with Gitelman Syndrome and a Subtle Intermediate Phenotype in Heterozygous Carriers: A Cross-Sectional Study. (2019) (21)
The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis. (2017) (21)
Estimated 24-h urinary sodium and sodium-to-potassium ratio are predictors of kidney function decline in a population-based study. (2019) (21)
Which type of dialysis in patients with cholesterol crystal embolism? (2002) (21)
Water and solute transport in peritoneal dialysis: models and clinical applications. (2008) (21)
An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis. (2021) (20)
Localization of a Band 3‐related protein in the mitochondria‐rich cells of amphibian skin epithelium (1993) (20)
Evaluating PVALB as a candidate gene for SLC12A3-negative cases of Gitelman's syndrome. (2008) (20)
Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. (2022) (20)
Digital Image Analysis of Picrosirius Red Staining: A Robust Method for Multi-Organ Fibrosis Quantification and Characterization (2020) (20)
Genetic and Clinical Predictors of Age of ESKD in Individuals With Autosomal Dominant Tubulointerstitial Kidney Disease Due to UMOD Mutations (2020) (20)
Inhibition of Nitric Oxide Synthase Reverses Permeability Changes in a Mouse Model of Acute Peritonitis (2005) (19)
New autosomal recessive mutations in aquaporin‐2 causing nephrogenic diabetes insipidus through deficient targeting display normal expression in Xenopus oocytes (2010) (19)
Decreased renal accumulation of aminoglycoside reflects defective receptor-mediated endocytosis in cystic fibrosis and Dent’s disease (2011) (19)
Paradoxical response to furosemide in uromodulin-associated kidney disease. (2015) (19)
A novel splicing mutation in SLC12A3 associated with Gitelman syndrome and idiopathic intracranial hypertension. (2006) (19)
Gitelman syndrome and glomerular proteinuria: a link between loss of sodium-chloride cotransporter and podocyte dysfunction? (2014) (19)
A population-based approach to assess the heritability and distribution of renal handling of electrolytes. (2017) (19)
AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. (2021) (19)
Renal involvement in a patient with cobalamin A type (cblA) methylmalonic aciduria: a 42-year follow-up. (2013) (19)
Influence of the endothelial nitric oxide synthase gene on conventional and ambulatory blood pressure: sib-pair analysis and haplotype study (2005) (18)
The anti-oxidative role of cytoglobin in podocytes: implications for a role in chronic kidney disease. (2020) (18)
The -174G/C variant of IL6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients. (2012) (18)
Clinical application of aquaporin research: aquaporin-1 in the peritoneal membrane (2008) (18)
Autoantibodies against intercalated cells in Sjögren's syndrome. (2009) (18)
Effect of N-acetyl-cysteine and hyperoxia on erythropoietin production (2011) (18)
NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis (2018) (18)
Influence of ACE (I/D) and G460W polymorphism of alpha-adducin in autosomal dominant polycystic kidney disease. (2003) (18)
TRPV4 is associated with central rather than nephrogenic osmoregulation (2016) (18)
The vasopressin system: new insights for patients with kidney diseases (2017) (18)
NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. (2017) (18)
Clinical utility gene card for (2011) (18)
Intrafamilial phenotype variability in nephrogenic diabetes insipidus. (2002) (18)
The excretion of uromodulin is modulated by the calcium-sensing receptor. (2018) (18)
High-dose steroid treatment increases free water transport in peritoneal dialysis patients. (2011) (17)
Sterile Chemical Peritonitis Secondary to Icodextrin: Immunohistopathological Description (2002) (17)
Association Studies of Calcium-Sensing Receptor (CaSR) Polymorphisms with Serum Concentrations of Glucose and Phosphate, and Vascular Calcification in Renal Transplant Recipients (2015) (17)
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Rationale and Design of a Clinical Trial Investigating Tolvaptan Safety and Efficacy in Autosomal Dominant Polycystic Kidney Disease (2017) (14)
Validation of Surrogates of Urine Osmolality in Population Studies (2017) (14)
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Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. (2015) (9)
Variable renal disease progression in autosomal dominant polycystic kidney disease: a role for nitric oxide? (2003) (9)
Aquaporin-1 in the peritoneal membrane: Implications for water transport across capillaries and peritoneal dialysis. (2006) (9)
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The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system (2011) (8)
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Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin (2022) (8)
Molecular Mechanisms of Peritoneal Permeability— Research in Growth Factors (2001) (8)
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The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease (2020) (7)
The Expression of Water Channels AQP1 and AQP2 in a Large Series of ADPKD Kidneys (1997) (7)
Calcineurin Inhibitors Downregulate HNF-1&bgr; and May Affect the Outcome of HNF1B Patients After Renal Transplantation (2016) (7)
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Ultrafiltration Failure and Impaired Sodium Sieving During Long-Term Peritoneal Dialysis: More Than Aquaporin Dysfunction? (2016) (6)
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4B.05: PLASMA COPEPTIN IS ASSOCIATED WITH INSULIN RESISTANCE IN A SWISS POPULATION-BASED STUDY (2015) (6)
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Cystic Gene Dosage Influences Kidney Lesions After Nephron Reduction (2014) (5)
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Peritoneal Dialysis: Nanoparticles Have Entered the Game (2015) (5)
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Intravital multi-photon microscopy reveals several levels of heterogeneity in endocytic uptake by mouse renal proximal tubules (2007) (5)
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Expression and Regulation of Aquaporin-1 and Endothelial Nitric Oxide Synthase in Relationship with Water Permeability Across the Peritoneum (2000) (5)
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SP262CAN WE FURTHER ENRICH ADPKD CLINICAL TRIALS FOR RAPIDLY PROGRESSIVE PATIENTS? APPLICATION OF THE PROPKD SCORE IN THE TEMPO TRIAL (2016) (4)
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METABOLIC ALKALOSIS IN THE INTENSIVE CARE UNIT (2001) (4)
Peritoneal Membrane Transport: Driving under the Influence (2006) (4)
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Renal Fanconi Syndrome, Dent’s Disease and Bartter’s Syndrome (2013) (3)
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5C.09: HERITABILITY OF RENAL FUNCTION PARAMETERS AND ELECTROLYTE LEVELS IN THE SWISS POPULATION (2015) (3)
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Editors' Digest – Basic Science A Wearable Sweat Analyzer for Continuous Electrolyte Monitoring (2016) (2)
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The Succinate Receptor 1 is a Physiological Regulator of the Renin‐Angiontensin Aldosterone System (2015) (2)
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The transcription factor HNF 1 regulates expression of chloride-proton exchanger ClC-5 in the renal proximal tubule (2010) (2)
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[Variable progression of autosomal dominant polycystic kidney disease: genetic and molecular counterparts]. (2006) (2)
Genetic Variants and Risk of Chronic Kidney Disease (2014) (2)
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Studying nonobstructive azoospermia in cystinosis: histologic examination of testes and epididymis and sperm analysis in a Ctns⁻/⁻ mouse model. (2012) (2)
The Effect of Tolvaptan on BP in Polycystic Kidney Disease: A Post Hoc Analysis of the TEMPO 3:4 Trial (2021) (2)
Assessing transport across the peritoneal membrane: Precision medicine in dialysis (2021) (1)
Critical role of aquaporins in IL-1-mediated inflammation (2018) (1)
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Flank pain has a significant adverse impact on quality of life in ADPKD: the CYSTic-QoL study (2022) (1)
Hypothyroidism, Congenital (2005) (1)
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Genome-Wide Methylation and Body-Mass Index (2014) (1)
Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency (2020) (1)
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Aseptic peritonitis due to peptidoglycan (2005) (1)
[Parvalbumin and regulation of ion transport in the distal convoluted tubule of the kidney]. (2010) (1)
Early diagnosis of dehydration in hospitalized geriatric patients using clinical and laboratory criteria (2018) (1)
Parathyroid hormone and phosphate homeostasis in patients with Bartter and Gitelman syndrome: an international cross-sectional study (2022) (1)
The − 174 G / C variant of IL 6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients (2012) (1)
Diagnosis of prostatitis by 18-F-fluorodeoxyglucose positron emission tomography (2008) (1)
Fasting influences aquaporin expression, water transport and adipocyte metabolism in the peritoneal membrane. (2022) (1)
Rab-GAP TBC 1 D 4 ( AS 160 ) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT 4 in mouse kidney (2015) (1)
Nitric oxide inhibits Aquaporin-1 water permeability through interaction on Cysteine 189 (2000) (1)
Multisystem involvement, defective lysosomes and impaired autophagy in a novel rat model of nephropathic cystinosis (2022) (1)
Ca19.9 Is a Diagnostic Marker for Hepatic Cyst Infection in Adpkd Kidney Transplant Patients (2009) (1)
Investigation of proximal tubule functions in a model of renal Fanconi syndrom by 99mTc-DMSA, 99mTc-MAG3 and 123I-beta2-microglobulin SPECT on conscious mice (2006) (1)
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MO023FLANK PAIN HAS A MAJOR NEGATIVE IMPACT ON HEALTH-RELATED QUALITY OF LIFE IN ADPKD: THE CYSTIC I STUDY (2021) (1)
Circulating Uromodulin and Risk of Cardiovascular Events and Kidney Failure. (2020) (1)
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ASSOCIATION OF HAPLOTYPES OF ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE (ENOS) WITH DAY AMBULATORY SYSTOLIC BLOOD PRESSURE: P1.184 (2004) (0)
Mechanisms of acid-base regulation in peritoneal dialysis (2017) (0)
Dietary salt and renal stone disease. (1997) (0)
HNF1ß: A gene, several phenotypes (2014) (0)
Polyuria and impaired NaCl and calcium handling in mice lacking parvalbumin (2005) (0)
Series introduction: drug repurposing for kidney diseases. (2023) (0)
On the way to translate GWAS into kidney disease mechanisms. (2022) (0)
TRPV4 is associated with central rather than nephrogenic osmoregulation (2016) (0)
Towards the intracellular location of human ClC-6 (2006) (0)
Aortic calcifications and cardiovascular events in renal transplant recipients: Influence of the Fetuin-A Gene and Serum Fetuin-A Levels (2009) (0)
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"Tubular cell plasticity - New hope for autosomal dominant polycystic kidney disease?" (2022) (0)
Faculty Opinions recommendation of Chronic peritoneal dialysis in the United States: declining utilization despite improving outcomes. (2007) (0)
ADPKD is associated with a central peripheral defect in osmoregulation (2010) (0)
Urine: from waste to fertilizer. (2022) (0)
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New Insight About Regulation of the Extracellular Fluid Volume By Aldosterone (1993) (0)
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Uromodulin and Vesico-Ureteral Reflux: A Genetic Study (2023) (0)
Rhcg disruption in mice demonstrates a role in luminal and basolateral NH3 transport in collecting ducts (2011) (0)
Mice lacking TRPV4 show abnormal thirst regulation in absence of renal defects (2010) (0)
The January 2013 Edition—A New Chapter for Peritoneal Dialysis International (2013) (0)
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A cyclin dependent kinase inhibitor 1B missense mutation (Pro69Leu) is associated with familial hypomagnesaemia, but not multiple endocrine neoplasia type 4 (MEN4) (2019) (0)
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Association fludrocortisone — indométhacine dans le traitement de l'hypotension orthostatique idiopathique (1992) (0)
AQP1 Promoter Variant, Water Transport, and Outcome in Peritoneal Dialysis. Reply. (2022) (0)
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Disruption of ClC-5 is not associated with defective proton secretion by the collecting duct (2011) (0)
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The determinants of pulse wave velocity in a large series of renal transplant recipients (2006) (0)
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PD Research Round-up: Sodium Sensing: Link to (Auto)immunity (2013) (0)
The Aminoglycoside Clearance Is Increased in Cystic Fibrosis and Dent's Disease Models of Proximal Tubule Dysfunction (2010) (0)
CIC-5 is an essential component of the endoytic machinery in proximal tubule cells (2002) (0)
Acetazolamide: an improved treatment for lithium‐induced NDI? (LB726) (2014) (0)
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (0)
Towards the subcellular location of human ClC-6: development of anti-ClC-6 antibody (2005) (0)
ClC5 knock-out induces multiple alterations in the endocytic apparatus of proximal tubular cells. (2002) (0)
Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency (2020) (0)
A mouse model of peritoneal dialysis reveals a predominant role of neuronal nitric oxide synthase in lipopolysaccharide-induced acute peritonitis. (2003) (0)
COPEPTIN IN CKD (2014) (0)
The adult with renal cysts (2015) (0)
Allelic and Gene Dosage Effects Involving Uromodulin Aggregates Drive Autosomal Dominant Tubulointerstitial Kidney Disease (2022) (0)
University of Groningen Tolvaptan and Kidney Pain in Patients With Autosomal Dominant Polycystic Kidney Disease (2018) (0)
MP359FGF23 AND MARKERS OF MINERAL METABOLISM IN SUBJECTS WITH PRESERVED RENAL FUNCTION (2016) (0)
Coronary calcifications predict cardiovascular events in renal transplant recipients (2008) (0)
The determinants of the evolution of coronary and aortic calcifications in renal transplant recipients (2010) (0)
CKD PATHOPHYSIOLOGY AND CLINICAL STUDIES (2014) (0)
Cystic fibrosis is associated with a defect in low molecular weight protein handling in the kidney. (2005) (0)
Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney (2018) (0)
PIEZO2, a mechanosensor in the urinary bladder. (2021) (0)

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