Olke Uhlenbeck
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Mathematics
Olke Uhlenbeck's Degrees
- PhD Mathematics Leiden University
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(Suggest an Edit or Addition)Olke Uhlenbeck's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Improved estimation of secondary structure in ribonucleic acids. (1973) (1858)
- Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. (1987) (1856)
- Synthesis of small RNAs using T7 RNA polymerase. (1989) (977)
- A small catalytic oligoribonucleotide (1987) (770)
- Diversity of oligonucleotide functions. (1995) (747)
- Stability of ribonucleic acid double-stranded helices. (1974) (592)
- Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. (1988) (513)
- Sequence requirements of the hammerhead RNA self-cleavage reaction. (1990) (399)
- Role of divalent metal ions in the hammerhead RNA cleavage reaction. (1991) (323)
- Specific labeling of 3' termini of RNA with T4 RNA ligase. (1980) (306)
- Uniform Binding of Aminoacyl-tRNAs to Elongation Factor Tu by Thermodynamic Compensation (2001) (298)
- CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes. (1988) (287)
- Numbering system for the hammerhead. (1992) (251)
- Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. (1993) (235)
- 3'-Phosphatase activity in T4 polynucleotide kinase. (1977) (232)
- A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. (1994) (228)
- Reactions at the termini of tRNA with T4 RNA ligase. (1978) (224)
- Keeping RNA happy. (1995) (193)
- Substrate sequence effects on "hammerhead" RNA catalytic efficiency. (1990) (187)
- Sequence-specific interaction of R17 coat protein with its ribonucleic acid binding site. (1983) (187)
- A small metalloribozyme with a two-step mechanism (1992) (179)
- Thermodynamics and kinetics of the helix‐coil transition of oligomers containing GC base pairs (1973) (173)
- Hammerhead ribozyme kinetics. (1998) (171)
- In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. (1992) (167)
- Kinetics of intermolecular cleavage by hammerhead ribozymes. (1992) (165)
- Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. (1993) (164)
- Enzymatic oligoribonucleotide synthesis with T4 RNA ligase. (1978) (162)
- RNA binding site of R17 coat protein. (1987) (158)
- Characterization of RNA hairpin loop stability. (1988) (157)
- Specific interaction between RNA phage coat proteins and RNA. (1991) (156)
- Inhibition of the hammerhead ribozyme by neomycin. (1969) (155)
- The structure-function dilemma of the hammerhead ribozyme. (2005) (138)
- Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction. (1990) (137)
- Escherichia coli DbpA is an RNA helicase that requires hairpin 92 of 23S rRNA (2001) (136)
- Nucleotides in yeast tRNAPhe required for the specific recognition by its cognate synthetase. (1989) (134)
- Stability of RNA hairpin loops: A6-Cm-U6 (1973) (132)
- T7 RNA polymerase produces 5' end heterogeneity during in vitro transcription from certain templates. (1998) (131)
- Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations. (2001) (130)
- Modulation of tRNAAla identity by inorganic pyrophosphatase (2002) (128)
- Self-complementary oligoribonucleotides: adenylic acid-uridylic acid block copolymers. (1971) (127)
- Structure of an unmodified tRNA molecule. (1989) (125)
- RNA template-directed RNA synthesis by T7 RNA polymerase. (1994) (125)
- Chemical and enzymatic synthesis of tRNAs for high-throughput crystallization. (2001) (121)
- Lead-catalyzed cleavage of yeast tRNAPhe mutants. (1990) (113)
- Role of a bulged A residue in a specific RNA-protein interaction. (1987) (109)
- Tetraloops and RNA folding (1990) (109)
- Complementary oligonucleotide binding to transfer RNA. (1972) (109)
- Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb. (1997) (102)
- The tRNA Specificity of Thermus thermophilus EF-Tu (2002) (101)
- Folding of circularly permuted transfer RNAs. (1991) (101)
- Self-complementary oligoribonucleotides: effects of helix defects and guanylic acid-cytidylic acid base pairs. (1971) (100)
- Uniform binding of aminoacylated transfer RNAs to the ribosomal A and P sites. (2004) (99)
- Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. (1994) (97)
- Chemical map of Schizosaccharomyces pombe reveals species-specific features in nucleosome positioning (2013) (97)
- The affinity of elongation factor Tu for an aminoacyl-tRNA is modulated by the esterified amino acid. (2004) (96)
- An RNA mutation that increases the affinity of an RNA-protein interaction. (1987) (96)
- The carboxy-terminal domain of the DExDH protein YxiN is sufficient to confer specificity for 23S rRNA. (2002) (96)
- Mutants of the bacteriophage MS2 coat protein that alter its cooperative binding to RNA. (1995) (92)
- Neomycin inhibition of the hammerhead ribozyme involves ionic interactions. (1995) (92)
- 12 Divalent Metal Ions in RNA Folding and Catalysis (1993) (92)
- The Escherichia coli DEAD protein DbpA recognizes a small RNA hairpin in 23S rRNA. (2001) (92)
- Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster. (1977) (91)
- A thermodynamic analysis of the sequence-specific binding of RNA by bacteriophage MS2 coat protein. (1998) (88)
- Kinetic and thermodynamic characterization of the R17 coat protein-ribonucleic acid interaction. (1983) (87)
- 2 T4 RNA Ligase (1982) (85)
- Idiosyncratic tuning of tRNAs to achieve uniform ribosome binding (2005) (85)
- Different aa-tRNAs are selected uniformly on the ribosome. (2008) (85)
- Roles of operator and non-operator RNA sequences in bacteriophage R17 capsid assembly. (1988) (84)
- 12 The Role of Metal Ions in RNA Biochemistry (1999) (84)
- [3'-32P]-labeling tRNA with nucleotidyltransferase for assaying aminoacylation and peptide bond formation. (2008) (83)
- Specific RNA binding by Q beta coat protein. (1989) (82)
- Ribonucleoprotein complexes of R17 coat protein and a translational operator analog. (1988) (82)
- Tuning the affinity of aminoacyl-tRNA to elongation factor Tu for optimal decoding (2011) (81)
- Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome. (2000) (80)
- Isolation and characterization of two mutant forms of T4 polynucleotide kinase. (1982) (79)
- Proton NMR and structural features of a 24-nucleotide RNA hairpin. (1995) (79)
- Kinetic analysis of the RNA-dependent adenosinetriphosphatase activity of DbpA, an Escherichia coli DEAD protein specific for 23S ribosomal RNA. (1998) (78)
- Determination of RNA-protein contacts using thiophosphate substitutions. (1989) (78)
- Amino acid specificity in translation. (2005) (78)
- Interaction of R17 coat protein with synthetic variants of its ribonucleic acid binding site. (1983) (75)
- Cooperative binding of ATP and RNA substrates to the DEAD/H protein DbpA. (2002) (74)
- Quantitative Assessment of EF-1α·GTP Binding to Aminoacyl-tRNAs, Aminoacyl-viral RNA, and tRNA Shows Close Correspondence to the RNA Binding Properties of EF-Tu* (1999) (74)
- Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. (2000) (73)
- A re-investigation of the thio effect at the hammerhead cleavage site. (1999) (73)
- Determination of recognition nucleotides for Escherichia coli phenylalanyl-tRNA synthetase. (1992) (72)
- Self‐cleaving catalytic RNA (1993) (72)
- A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit (2009) (71)
- In vitro analysis of translational rate and accuracy with an unmodified tRNA. (1993) (71)
- Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase. (1978) (70)
- Properties of an in vitro selected Pb2+ cleavage motif. (1994) (70)
- Cloning and biochemical characterization of Bacillus subtilis YxiN, a DEAD protein specifically activated by 23S rRNA: delineation of a novel sub-family of bacterial DEAD proteins. (1999) (69)
- tRNA residues that have coevolved with their anticodon to ensure uniform and accurate codon recognition. (2006) (69)
- The effect of base mismatches in the substrate recognition helices of hammerhead ribozymes on binding and catalysis. (1995) (68)
- RNA aptamers as pathway-specific MAP kinase inhibitors. (2000) (66)
- When to believe what you see. (2006) (66)
- Role of the tertiary nucleotides in the interaction of yeast phenylalanine tRNA with its cognate synthetase. (1990) (65)
- Enzymatic replacement of the anticodon of yeast phenylalanine transfer ribonucleic acid. (1982) (64)
- T4-induced RNA ligase joins single-stranded oligoribonucleotides. (1975) (64)
- The self-splicing RNA of Tetrahymena is trapped in a less active conformation by gel purification. (1990) (63)
- Dinucleoside pyrophosphate are substrates for T4-induced RNA ligase. (1977) (63)
- YxiN Is a Modular Protein Combining a DExD/H Core and a Specific RNA-binding Domain* (2005) (63)
- The internal equilibrium of the hammerhead ribozyme reaction. (1995) (62)
- Probing the binding of Tb(III) and Eu(III) to the hammerhead ribozyme using luminescence spectroscopy. (1999) (62)
- Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis. (2009) (61)
- Equimolar addition of oligoribonucleotides with T4 RNA ligase (1977) (61)
- Studies on the hammerhead RNA self-cleaving domain. (1989) (61)
- The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold. (2006) (60)
- Joining of RNA molecules with RNA ligase. (1983) (60)
- Hammerhead redux: does the new structure fit the old biochemical data? (2008) (57)
- Interaction of Escherichia coli host factor protein with oligoriboadenylates. (1980) (55)
- Mutation of the arginine finger in the active site of Escherichia coli DbpA abolishes ATPase and helicase activity and confers a dominant slow growth phenotype (2007) (55)
- Interaction of R17 coat protein with its RNA binding site for translational repression. (1983) (55)
- Hammerhead ribozymes with a faster cleavage rate. (1997) (55)
- Hammerheads derived from sTRSV show enhanced cleavage and ligation rate constants. (2005) (53)
- Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes. (1983) (53)
- Sequence-dependent structural variations of hammerhead RNA enzymes. (1990) (52)
- Predicting the binding affinities of misacylated tRNAs for Thermus thermophilus EF-Tu.GTP. (2005) (51)
- Mutagenesis of a stacking contact in the MS2 coat protein‐RNA complex. (1996) (51)
- A sequence element that tunes E. coli tRNAGGCAla to ensure accurate decoding (2009) (50)
- A specific, UV-induced RNA-protein cross-link using 5-bromouridine-substituted RNA. (1991) (50)
- A new assay for tRNA aminoacylation kinetics. (1998) (49)
- Recognition of tertiary structure in tRNAs by Rh(phen)2phi3+, a new reagent for RNA structure-function mapping. (1992) (49)
- Recognition nucleotides for human phenylalanyl-tRNA synthetase. (1992) (48)
- Use of intrinsic binding energy for catalysis by an RNA enzyme. (1997) (48)
- RNA Recognition by the MS2 Phage Coat Protein (1997) (48)
- Contribution of the esterified amino acid to the binding of aminoacylated tRNAs to the ribosomal P- and A-sites. (2004) (47)
- The 51-63 base pair of tRNA confers specificity for binding by EF-Tu. (2007) (46)
- Thermal stability of RNA hairpins containing a four-membered loop and a bulge nucleotide. (1989) (46)
- An RNA-protein contact determined by 5-bromouridine substitution, photocrosslinking and sequencing. (1994) (45)
- Specific substitution into the anticodon loop of yeast tyrosine transfer RNA. (1986) (45)
- Binding of complementary oligonucleotides to free and aminoacyl transfer ribonucleic acid synthetase bound transfer ribonucleic acid. (1972) (44)
- Polynucleotide kinase from a T4 mutant which lacks the 3' phosphatase activity. (1978) (43)
- Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis. (2007) (43)
- RNA Structure Comes of Age (1997) (43)
- Circularly permuted DNA, RNA and proteins--a review. (1993) (43)
- Characterization of two RNA-catalyzed RNA cleavage reactions. (1987) (42)
- Many of the conserved nucleotides of tRNA(Phe) are not essential for ternary complex formation and peptide elongation. (1994) (41)
- Hammerhead nailed down (1994) (40)
- A covalent crosslink converts the hammerhead ribozyme from a ribonuclease to an RNA ligase (2001) (39)
- Recognition of yeast tRNA(Phe) by its cognate yeast phenylalanyl-tRNA synthetase: an analysis of specificity. (1992) (38)
- Guanosine modifications in runoff transcripts of synthetic transfer RNA-Phe genes microinjected into Xenopus oocytes. (1990) (38)
- Nucleoside and nucleotide inactivation of R17 coat protein: evidence for a transient covalent RNA-protein bond. (1985) (36)
- Catalytic diversity of extended hammerhead ribozymes. (2008) (36)
- Cooperative binding of R17 coat protein to RNA. (1990) (35)
- Using phosphorothioate-substituted RNA to investigate the thermodynamic role of phosphates in a sequence specific RNA-protein complex. (2000) (35)
- Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA. (2001) (35)
- Specific interaction of anticodon loop residues with yeast phenylalanyl-tRNA synthetase. (1982) (35)
- Circular dichroism study of nine species of transfer ribonucleic acid. (1972) (34)
- Directed mutagenesis identifies amino acid residues involved in elongation factor Tu binding to yeast Phe-tRNAPhe. (2007) (34)
- Interaction of Escherichia coli DbpA with 23S rRNA in different functional states of the enzyme. (2004) (33)
- Interaction of Escherichia coli host factor protein with Q beta ribonucleic acid. (1980) (33)
- PMR or the self-complementary oligoribonucleotide CpCpGpG. (1974) (32)
- Escherichia coli DbpA is a 3' --> 5' RNA helicase. (2005) (31)
- Less isn't always more. (2003) (31)
- RNA binding properties of the coat protein from bacteriophage GA. (1991) (31)
- The role of 2'-hydroxyl groups in an RNA-protein interaction. (1995) (30)
- Effect of replacing uridine 33 in yeast tRNAPhe on the reaction with ribosomes. (1986) (28)
- Exploring the specificity of bacterial elongation factor Tu for different tRNAs. (2007) (27)
- Is the sequence-specific binding of aminoacyl-tRNAs by EF-Tu universal among bacteria? (2011) (27)
- Uridine-33 in yeast tRNA not essential for amber suppression (1983) (26)
- Kinetic characterization of two I/II format hammerhead ribozymes. (1996) (26)
- Enzymatic synthesis of a 21-nucleotide coat protein binding fragment of R17 ribonucleic acid. (1982) (25)
- The hammerhead ribozyme. (2001) (25)
- Oligonucleotide binding to the native and denatured conformers of yeast transfer RNA-3 Lea. (1974) (24)
- Internal equilibrium of the hammerhead ribozyme is altered by the length of certain covalent cross-links. (2002) (24)
- Use of T4 RNA ligase to construct model substrates for a ribosomal RNA maturation endonuclease. (1978) (23)
- Aminoacylation of anticodon loop substituted yeast tyrosine transfer RNA. (1985) (23)
- Specificity of the ribosomal A site for aminoacyl-tRNAs (2008) (23)
- Divalent metal ions and the internal equilibrium of the hammerhead ribozyme. (1995) (23)
- A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme. (1997) (23)
- An ultraviolet light-induced crosslink in yeast tRNAPhe (1992) (23)
- In vitro selection of DNAs with an increased propensity to form small circles (2015) (23)
- Hammerhead cleavage of the phosphorodithioate linkage. (2000) (22)
- Characterization of deoxy- and ribo-containing oligonucleotide substrates in the hammerhead self-cleavage reaction. (1990) (22)
- Duplex destabilization by four ribosomal DEAD-box proteins. (2012) (22)
- Role of the constant uridine in binding of yeast tRNAPhe anticodon arm to 30S ribosomes. (1982) (22)
- Replacement of anticodon loop nucleotides to produce functional tRNAs: amber suppressors derived from yeast tRNAPhe. (1982) (21)
- A Better Way to Make RNA for Physical Studies (1986) (21)
- Defining a smaller RNA substrate for elongation factor Tu. (1995) (21)
- Stability of RNA hairpin loops: A 6 -C m -U 6 . (1973) (20)
- Replacement of RNA hairpins by in vitro selected tetranucleotides. (1993) (19)
- Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme. (1998) (19)
- In vitro selection of small RNAs that bind to Escherichia coli phenylalanyl-tRNA synthetase. (1994) (19)
- tRNA residues evolved to promote translational accuracy. (2013) (18)
- Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins. (2008) (18)
- Specific replacement of functional groups of uridine-33 in yeast phenylalanine transfer ribonucleic acid. (1985) (18)
- Cryoenzymology of the hammerhead ribozyme. (1998) (17)
- A coat for all sequences (1998) (17)
- Quantitative analysis of deoxynucleotide substitutions in the codon-anticodon helix. (2006) (17)
- Mapping contacts between Escherichia coli alanyl tRNA synthetase and 2' hydroxyls using a complete tRNA molecule. (2000) (17)
- Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state. (1997) (17)
- Evolutionary tuning impacts the design of bacterial tRNAs for the incorporation of unnatural amino acids by ribosomes. (2018) (17)
- Some Effects on Noncomplementary Bases on the Stability of Helical Complexes of Polyribonucleotides (1968) (16)
- Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme. (1998) (16)
- 4S RNA Gene Organization in Drosophila melanogaster (1980) (16)
- Binding of misacylated tRNAs to the ribosomal A site. (2005) (15)
- Removal of Y-37 from tRNAyeastphe alters oligomer binding to two loops (1973) (15)
- Evaluation of methylphosphonates as analogs for detecting phosphate contacts in RNA-protein complexes. (2001) (15)
- Chromosomal sites of integration of simian virus 40 DNA sequences mapped by in situ hybridization in two transformed hybrid cell lines (1984) (15)
- Using circular permutation analysis to redefine the R17 coat protein binding site. (1993) (15)
- Stepwise enzymatic oligoribonucleotide synthesis including modified nucleotides. (1975) (15)
- Circular dichroism of double-helical oligoribonucleotides. (1973) (14)
- Reversal of T4 RNA ligase. (1982) (14)
- Steric interference modification of the hammerhead ribozyme. (2002) (13)
- The Interface between Escherichia coli Elongation Factor Tu and Aminoacyl-tRNA (2014) (13)
- Independent locations of kinase and 3'-phosphatase activities on T4 polynucleotide kinase. (1982) (13)
- Histidine 66 in Escherichia coli Elongation Factor Tu Selectively Stabilizes Aminoacyl-tRNAs* (2011) (12)
- tRNA conformity. (2001) (11)
- Modifying the specificity of an RNA backbone contact. (2001) (10)
- 18 – Recognition of RNA by Proteins (1987) (9)
- In situ hybridization of three transfer RNAs to the polytene chromosomes of Drosophila melanogaster. (1980) (9)
- An ultraviolet light-induced crosslink in yeast tRNA(Phe). (1992) (9)
- T4 RNA ligase (1983) (9)
- Alanine scanning of MS2 coat protein reveals protein-phosphate contacts involved in thermodynamic hot spots. (2006) (8)
- T4 RNA ligase as a nucleic acid synthesis and modification reagent. (1981) (8)
- Circular substrates of the hammerhead ribozyme shift the internal equilibrium further toward cleavage. (1998) (8)
- A comparison of two phage coat protein-RNA interactions. (1988) (7)
- Enhanced product stability in the hammerhead ribozyme. (2010) (7)
- RNA biophysics has come of age. (2009) (6)
- Labeled EF-Tus for Rapid Kinetic Studies of Pretranslocation Complex Formation (2014) (6)
- The specific interaction between aminoacyl-tRNAs and elongation factor Tu (2011) (5)
- Ribozymes. Hammerhead nailed down. (1994) (5)
- Quantitation of in situ hybridization of ribosomal ribonucleic acids to human diploid cells (1980) (5)
- Functional consequences of T-stem mutations in E. coli tRNAThrUGU in vitro and in vivo. (2011) (4)
- Structure and mechanism of the hammerhead self-cleaving domain. (1989) (3)
- Bringing RNA into View: RNA and Its Roles in Biology. (2000) (3)
- Studies on the hammerhead RNA self-cleaving domain**Presented at the Albany Conference on ‘RNA: Catalysis, Splicing, Evolution’, Rensselaerville, NY (U.S.A.) 22-25 September 1988. (1989) (3)
- Failure of translational repression in the phage f2 op3 mutant is not due to an altered coat protein-RNA interaction. (1984) (3)
- Hammerhead: Part 2 (1995) (2)
- Dinucleoside pyrophosphates are substrates for T 4-induced RNA ligase ( RNA synthesis / RNA 3 '-modification / NAD + / nucleotides / enzyme mechanism ) (1)
- Hasty decisions on the ribosome (2004) (1)
- Abstracts of papers presented at the 1990 Meeting on RNA Processing, May 16-May 20, 1990 (1990) (0)
- The mechanism of the hammerhead ribozyme (1993) (0)
- Understanding the Sequence Specificity of tRNA Binding to EF-Tu using tRNA Mutagenesis† (2009) (0)
- Erratum: Differential RNA-dependent ATPase activities of four rRNA processing yeastDEAD-box proteins (Biochemistry (2008) 47:47 (12562-12573)) (2009) (0)
- Obituary (L. Recalde) (2010) (0)
- Replacement of anticodon-loop nucleotides to produce functional tRNAs (1984) (0)
- Quantitative Assessment of EF1 a z GTP Binding to Aminoacyl-tRNAs , Aminoacyl-viral RNA , and tRNA (1998) (0)
- 24-MER RNA HAIRPIN COAT PROTEIN BINDING SITE FOR BACTERIOPHAGE R17 (NMR, MINIMIZED AVERAGE STRUCTURE) (1995) (0)
- Why tRNAs are Different (2006) (0)
- Kinetic and spectroscopic consequences of site-specific terbium(III) binding to the hammerhead ribozyme (1997) (0)
- Removal of Y-37 from tRNA phe yeast alters oligomer binding to two loops. (1973) (0)
- Tuning tRNA Sequences for Optimal Translation (2013) (0)
- MinireviewWhen to Believe What You See (0)
- Obituary (2010) (0)
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