Olle Korsgren

Q: What Schools Are Affiliated With Olle Korsgren

Olle Korsgren is affiliated with the following schools: Stockholm University, Uppsala University, Chalmers University of Technology, University of Gothenburg, Lund University, Karolinska Institute

Olle Korsgren's AcademicInfluence.com Rankings

Olle Korsgren

Chemistry

#4113

World Rank

#5175

Historical Rank

Inorganic Chemistry

#217

World Rank

#231

Historical Rank

chemistry Degrees

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Chemistry

Olle Korsgren's Degrees

PhD Chemistry Uppsala University
Masters Chemical Engineering Chalmers University of Technology

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Olle Korsgren's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation (2002) (555)
Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia (2016) (438)
Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? (1999) (437)
No evidence of infection with porcine endogenous retrovirus in recipients of porcine islet-cell xenografts (1998) (368)
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets. (2012) (341)
Isolated Human Islets Trigger an Instant Blood Mediated Inflammatory Reaction: Implications for Intraportal Islet Transplantation as a Treatment for Patients with Type 1 Diabetes (2000) (333)
Transplantation of porcine fetal pancreas to diabetic patients (1994) (316)
Identification of proliferative and mature β-cells in the islets of Langerhans (2016) (275)
Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice (1999) (269)
Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. (2002) (267)
Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood? (2012) (263)
Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice (1997) (261)
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. (2003) (256)
Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes (2014) (242)
Refinement of the Automated Method for Human Islet Isolation and Presentation of a Closed System for In Vitro Islet Culture (2004) (232)
Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation (2007) (221)
Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation. (2005) (210)
Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells (2014) (208)
Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. (2000) (205)
Current Advances and Travails in Islet Transplantation (2009) (191)
Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation. (2003) (174)
Widespread amyloid deposition in transplanted human pancreatic islets. (2008) (169)
Optimising islet engraftment is critical for successful clinical islet transplantation (2008) (163)
Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment (2011) (163)
The diagnosis of insulitis in human type 1 diabetes (2013) (162)
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane (2008) (155)
Positron Emission Tomography in Clinical Islet Transplantation (2009) (154)
THE MAIN INFILTRATING CELL IN XENOGRAFT REJECTION IS A CD4+ MACROPHAGE AND NOT A T LYMPHOCYTE (1995) (148)
Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study (2014) (143)
Intramuscular Autotransplantation of Pancreatic Islets in a 7‐Year‐Old Child: A 2‐Year Follow‐Up (2008) (143)
Unique basement membrane structure of human pancreatic islets: implications for β‐cell growth and differentiation (2008) (141)
Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? (2010) (140)
National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities (2016) (135)
Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets (2005) (131)
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation1 (2003) (131)
Low Molecular Weight Dextran Sulfate: A Strong Candidate Drug to Block IBMIR in Clinical Islet Transplantation (2006) (128)
Dissecting the instant blood‐mediated inflammatory reaction in islet xenotransplantation (2008) (124)
TISSUE FACTOR RELEASED BY THE ENDOCRINE CELLS OF THE ISLETS OF LANGERHANS IS ASSOCIATED WITH A NEGATIVE OUTCOME OF CLINICAL ISLET TRANSPLANTATION (2004) (124)
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome (2015) (122)
Effects of Hyperglycemia on Function of Isolated Mouse Pancreatic Islets Transplanted Under Kidney Capsule (1989) (115)
The ADP/ATP Ratio: A Novel Predictive Assay for Quality Assessment of Isolated Pancreatic Islets (2006) (115)
Formation of Composite Endothelial Cell–Mesenchymal Stem Cell Islets (2008) (114)
Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus (2018) (114)
Ultrastructural studies of the ontogeny of fetal human and porcine endocrine pancreas, with special reference to colocalization of the four major islet hormones. (1992) (112)
LARGE‐SCALE PRODUCTION OF FETAL PORCINE PANCREATIC ISLETLIKE CELL CLUSTERS: An Experimental Tool for Studies of Islet Cell Differentiation and Xenotransplantation (1988) (107)
Insulin-Heparin Infusions Peritransplant Substantially Improve Single-Donor Clinical Islet Transplant Success (2010) (105)
Intraportally Transplanted Pancreatic Islets Revascularized From Hepatic Arterial System (1989) (104)
Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets (2004) (104)
Interferons induce an antiviral state in human pancreatic islet cells. (2007) (103)
Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background. (1990) (101)
Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle (2010) (101)
Positron Emission Tomography: A Real-Time Tool to Quantify Early Islet Engraftment in a Preclinical Large Animal Model (2007) (97)
Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants. (2000) (93)
In Vivo Imaging of the Glucagonlike Peptide 1 Receptor in the Pancreas with 68Ga-Labeled DO3A-Exendin-4 (2013) (90)
Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice. (1996) (90)
In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells (2005) (88)
Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO‐compatible blood (2005) (88)
Acute Antibody-Mediated Complement Activation Mediates Lysis of Pancreatic Islets Cells and May Cause Tissue Loss in Clinical Islet Transplantation (2008) (87)
Ultrastructural evidence for blood microvessels devoid of an endothelial cell lining in transplanted pancreatic islets. (1995) (85)
γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes (2012) (85)
Adenovirus CD40 Ligand Gene Therapy Counteracts Immune Escape Mechanisms in the Tumor Microenvironment1 (2004) (85)
Pretreatment of fetal porcine pancreas in culture with nicotinamide accelerates reversal of diabetes after transplantation to nude mice. (1993) (84)
Transplantation of porcine fetal pancreas to a diabetic patient. (1992) (83)
Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: an immunohistochemical study. (1999) (83)
No Beneficial Effect of Two-Layer Storage Compared With UW-Storage on Human Islet Isolation and Transplantation (2007) (82)
Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro (2015) (81)
Detection of metastatic insulinoma by positron emission tomography with [(68)ga]exendin-4-a case report. (2014) (81)
The Instant Blood-Mediated Inflammatory Reaction Characterized in Hepatocyte Transplantation (2011) (81)
Pig islet xenograft rejection is markedly delayed in macrophage‐depleted mice: a study in streptozotocin diabetic animals (2000) (80)
Current status of clinical islet transplantation. (2005) (79)
Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes. (2007) (76)
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes (2016) (74)
Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease (2013) (73)
Composite Islet‐Endothelial Cell Grafts: A Novel Approach to Counteract Innate Immunity in Islet Transplantation (2005) (71)
On the etiology of type 1 diabetes: a new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response. (2012) (69)
Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement (2016) (67)
EXPRESSION OF COMPLEMENT REGULATORY PROTEINS ON ISLETS OF LANGERHANS: A COMPARISON BETWEEN HUMAN ISLETS AND ISLETS ISOLATED FROM NORMAL AND hDAF TRANSGENIC PIGS1 (2001) (65)
REINNERVATION OF TRANSPLANTED PANCREATIC ISLETS: A COMPARISON AMONG ISLETS IMPLANTED INTO THE KIDNEY, SPLEEN, AND LIVER (1993) (65)
Positron Emission Tomography Ligand [11C]5-Hydroxy-Tryptophan Can Be Used as a Surrogate Marker for the Human Endocrine Pancreas (2014) (65)
Cellular responses to cytomegalovirus in immunosuppressed patients: circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment (2003) (64)
A comparison of fetal and adult porcine islets with regard to Gal alpha (1,3)Gal expression and the role of human immunoglobulins and complement in islet cell cytotoxicity. (2000) (64)
Islet Encapsulation: Physiological Possibilities and Limitations (2017) (62)
Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice (1991) (61)
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates. (2012) (61)
Discordant neural tissue xenografts survive longer in immunoglobulin deficient mice. (1999) (61)
In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass. (2010) (60)
Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis. (2010) (59)
Reinnervation of Syngeneic Mouse Pancreatic Islets Transplanted Into Renal Subcapsular Space (1992) (58)
Treatment Efficacy and Immune Stimulation by AdCD40L Gene Therapy of Spontaneous Canine Malignant Melanoma (2013) (57)
The Importance of Tryptic-like Activity in Purified Enzyme Blends for Efficient Islet Isolation (2009) (55)
Xenograft rejection of porcine islet-like cell clusters in immunoglobulin- or Fc-receptor gamma-deficient mice. (1996) (55)
First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes—Chapter 4: pre‐clinical efficacy and complication data required to justify a clinical trial (2016) (53)
Acute cellular xenograft rejection (1997) (53)
A distinct Th1 immune response precedes the described Th2 response in islet xenograft rejection. (2002) (52)
Efficient Adenovector CD40 Ligand Immunotherapy of Canine Malignant Melanoma (2008) (52)
Transplantation of fetal porcine pancreas to diabetic or normoglycemic nude mice. Evidence of a rapid engraftment process demonstrated by blood flow and heat shock protein 70 measurements. (1995) (52)
Potent antitumor effects of CD154 transduced tumor cells in experimental bladder cancer. (2001) (51)
Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations (1988) (50)
Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes. (2017) (50)
Infection of human islets of langerhans with two strains of coxsackie B virus serotype 1: Assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway (2014) (49)
Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction (2012) (49)
Human Islet Separation Utilizing a Closed Automated Purification System (2008) (48)
Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine A, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days. (2000) (48)
Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood‐mediated inflammatory reaction (2004) (47)
Glucocorticoids reduce pro‐inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo (2008) (46)
Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation (2011) (45)
Differentiation and maturation of porcine fetal islet cells in vitro and after transplantation. (1999) (45)
Positron emission tomography imaging of the glucagon-like peptide-1 receptor in healthy and streptozotocin-induced diabetic pigs (2014) (45)
Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms (2012) (43)
Type 1 Diabetes Mellitus Donor Mesenchymal Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro (2016) (43)
CMV‐specific T‐cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study (2009) (43)
Efficacy of immunosuppressive drugs in islet xenotransplantation: leflunomide in combination with cyclosporine and mycophenolate mofetil prevents islet xenograft rejection in the pig-to-rat model. (1997) (42)
Tissue Culture of Human Fetal Pancreas; Effects of Nicotinamide on Insulin Production and Formation of Isletlike Cell Clusters (1989) (42)
Induction of an Antiviral State and Attenuated Coxsackievirus Replication in Type III Interferon-Treated Primary Human Pancreatic Islets (2013) (41)
Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig* (2011) (41)
A New Oxygen Carrier for Improved Long-Term Storage of Human Pancreata Before Islet Isolation (2010) (41)
Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts (2012) (40)
Large-scale bioreactor expansion of tumor-infiltrating lymphocytes. (2011) (40)
An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets (2016) (40)
Large-Scale Comparison of Liberase HI and Collagenase NB1 Utilized for Human Islet Isolation (2010) (39)
Xenoislet transplantation: experimental and clinical aspects (1999) (39)
Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization (2018) (39)
Induction of the chemokine interferon-γ-inducible protein-10 in human pancreatic islets during enterovirus infection (2006) (38)
Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross‐reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins (2013) (37)
Phase 3 trial of human islet‐after‐kidney transplantation in type 1 diabetes (2020) (37)
The Ratio Between Collagenase Class I and Class II Influences the Efficient Islet Release From the Rat Pancreas (2008) (37)
Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo. (2004) (37)
Cytomegalovirus‐Specific CD4 and CD8 T Cell Responses in Infants and Children (2013) (36)
Quantitative Imaging of Serotonergic Biosynthesis and Degradation in the Endocrine Pancreas (2014) (36)
Quantification of the Islet Product: Presentation of a Standardized Current Good Manufacturing Practices Compliant System With Minimal Variability (2011) (36)
T Cell Control of Primary and Latent Cytomegalovirus Infections in Healthy Subjects (2005) (36)
Lack of antibody production against Hanganutziu‐Deicher (H‐D) antigens with N‐glycolylneuraminic acid in patients with porcine exposure history (2000) (35)
Discordant cellular xenografts revascularized in intermediate athymic hosts fail to induce a hyperacute rejection when transplanted to immunocompetent rats. (1994) (35)
Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes (2009) (35)
Increased Inflammatory Response in Cytomegalovirus Seropositive Patients with Alzheimer’s Disease (2014) (35)
Immunological Characteristics of Islet Cell Xenotransplantation in Humans and Rodents (1994) (34)
Transplantation of porcine fetal islet-like cell clusters into eight diabetic patients. (1992) (34)
Characterization of human organ donors testing positive for type 1 diabetes‐associated autoantibodies (2015) (34)
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo. (2017) (33)
Xenograft rejection of porcine islet-like cell clusters in normal, interferon-gamma, and interferon-gamma receptor deficient mice. (1997) (33)
Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET (2011) (33)
Insulitis in human diabetes: a histological evaluation of donor pancreases (2016) (33)
Vitacyte collagenase HA: a novel enzyme blend for efficient human islet isolation. (2009) (33)
Tissue culture of human fetal pancreas: growth hormone stimulates the formation and insulin production of islet-like cell clusters. (1987) (33)
A new method for incorporating functional heparin onto the surface of islets of Langerhans. (2008) (33)
Characterization of cellular human anti-porcine xenoreactivity (1993) (32)
Survival of fetal porcine pancreatic islet tissue transplanted to a diabetic patient: Findings by ultrastructural immunocytochemistry (1998) (32)
Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans. (2005) (32)
Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures (2013) (32)
The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling (2014) (32)
Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections. (1994) (32)
Resolvin E1 reduces proinflammatory markers in human pancreatic islets in vitro. (2010) (31)
Sustained reversal of diabetes following islet transplantation to striated musculature in the rat. (2010) (31)
Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation. (2008) (31)
GPR44 is a pancreatic protein restricted to the human beta cell (2016) (31)
Anakinra and Tocilizumab Enhance Survival and Function of Human Islets during Culture: Implications for Clinical Islet Transplantation (2014) (30)
Procurement of human pancreases for islet isolation-the initiation of a Scandinavian collaborative network. (2001) (30)
Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced (2019) (29)
Direct Substrate Delivery Into Mitochondrial Fission–Deficient Pancreatic Islets Rescues Insulin Secretion (2017) (29)
Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism (2009) (29)
In Vivo Visualization of β-Cells by Targeting of GPR44 (2017) (29)
Effects of Immunosuppressive Drugs on In Vitro Neogenesis of Human Islets: Mycophenolate Mofetil Inhibits the Proliferation of Ductal Cells (2007) (28)
PANCREATIC ISLET BLOOD FLOW AFTER SYNGENEIC PANCREATICODUODENAL TRANSPLANTATION IN RATS (1992) (28)
Porcine Islet-Like Cell Clusters Cure Diabetic Nude Rats when Transplanted under the Kidney Capsule, But not when Implanted into the Liver or Spleen (1994) (28)
Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro (2011) (28)
Antiviral effect of nicotinamide on enterovirus‐infected human islets in vitro: Effect on virus replication and chemokine secretion (2009) (28)
Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement. (2016) (28)
Transplanted Functional Islet Mass: Donor, Islet Preparation, and Recipient Factors Influence Early Graft Function in Islet-After-Kidney Patients (2012) (27)
Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity (2004) (27)
T cells in islet-like cell cluster xenograft rejection: a study in the pig-to-mouse model. (1998) (27)
The effect of macrophage depletion on delayed xenograft rejection: studies in the guinea pig‐to‐C6‐deficient rat heart transplantation model (1999) (26)
Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells. (1996) (26)
DIABETIC RATS TRANSPLANTED WITH ADULT PORCINE ISLETS AND IMMUNOSUPPRESSED WITH CYCLOSPORINE A, MYCOPHENOLATE MOFETIL, AND LEFLUNOMIDE REMAIN NORMOGLYCEMIC FOR UP TO 100 DAYS1 (2001) (26)
Clinical aspects and perspectives in islet xenotransplantation. (2000) (26)
Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system. (2014) (25)
A new murine model of islet xenograft rejection: graft destruction is dependent on a major histocompatibility-specific interaction between T-cells and macrophages. (2003) (25)
Immunosuppression with FTY720 and cyclosporine A inhibits rejection of adult porcine islet xenografts in rats (2003) (25)
Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle (2015) (25)
Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation (2016) (24)
Characterization of humoral human antiporcine xenoreactivity (1993) (24)
Quality of Isolated Pig Islets is Improved Using Perfluorohexyloctane for Pancreas Storage in a Split Lobe Model (2013) (24)
Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma. (2014) (23)
In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome (2015) (23)
Open Randomized Multicenter Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation (2019) (23)
Mesenchymal stromal cells support endothelial cell interactions in an intramuscular islet transplantation model (2015) (23)
Angiogenesis and angioarchitecture of transplanted fetal porcine islet-like cell clusters. (1999) (23)
Decreased Proportion of Cytomegalovirus Specific CD8 T-Cells but No Signs of General Immunosenescence in Alzheimer’s Disease (2013) (22)
KEY FACTORS FOR HUMAN ISLET ISOLATION AND CLINICAL TRANSPLANTATION (2004) (22)
Polyamine requirements in nicotinamide-stimulated beta-cell differentiation in fetal porcine islet-like cell clusters. (1994) (22)
Factors impeding the discovery of an intervention‐based treatment for type 1 diabetes (2016) (22)
Using HTK for prolonged pancreas preservation prior to human islet isolation. (2012) (22)
Distribution of the Galalpha1-3Gal antigen in cultured adult and fetal porcine pancreatic islet cells: an immunoelectron microscopic study. (2000) (22)
[11C]5-hydroxy-tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes (2017) (22)
Tropism Analysis of Two Coxsackie B5 Strains Reveals Virus Growth in Human Primary Pancreatic Islets but not in Exocrine Cell Clusters In Vitro (2013) (21)
Enhanced Survival of Porcine Neural Xenografts in Mice Lacking CD1d1, But No Effect of NK1.1 Depletion (2001) (21)
Islet Gene View—a tool to facilitate islet research (2018) (21)
Adenovirus-mediated expression of human CD55 or CD59 protects adult porcine islets from complement-mediated cell lysis by human serum1 (2003) (21)
Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation. (2012) (21)
Expression of human leukocyte antigen class I in endocrine and exocrine pancreatic tissue at onset of type 1 diabetes. (2015) (21)
Allogeneic and xenogeneic islets are rejected by different and specific mechanisms: A study in rodents using a mixed allogeneic‐xenogeneic islet transplantation model (1997) (20)
Mammalian tissue-free liberase: a new GMP-graded enzyme blend for human islet isolation. (2010) (20)
Pathogen Inactivation of Human Serum Facilitates its Clinical Use for Islet Cell Culture and Subsequent Transplantation (2011) (20)
The transplanted fetal endocrine pancreas undergoes an inherent sequential differentiation similar to that in the native pancreas. An ultrastructural study in the pig-to-mouse model. (2001) (20)
DNA replication in transplanted and endogenous pancreatic islets of obese-hyperglycemic mice at different stages of the syndrome. (1989) (20)
Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice. (2000) (20)
Low Molecular Weight Dextran Sulfate Is Well Tolerated in Humans and Increases Endogenous Expression of Islet Protective Hepatocyte Growth Factor (2008) (20)
Islet Engraftment and Revascularization in Clinical and Experimental Transplantation (2013) (20)
Antiviral treatment of Coxsackie B virus infection in human pancreatic islets. (2007) (20)
Xenograft rejection of fetal porcine islet‐like cell clusters in the rat: effects of active and passive immunization (1999) (19)
Human islet distribution programme for basic research: activity over the last 5 years (2015) (19)
Co-Stimulatory Molecules in Islet Xenotransplantation: CTLA4Ig Treatment in CD40 Ligand-Deficient Mice (2002) (19)
MyD88‐dependent toll‐like receptor signalling is not a requirement for fetal islet xenograft rejection in mice (2004) (18)
Long‐term engraftment and function of transplanted pancreatic islets in vascularized segments of small intestine (2011) (18)
Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic beta-cells. (2020) (18)
Human Pancreatic Islet Preparations Release HMGB1: (Ir)Relevance for Graft Engraftment (2013) (17)
Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation. (2012) (17)
In vitro screening of putative compounds inducing fetal porcine pancreatic beta-cell differentiation: implications for cell transplantation in insulin-dependent diabetes mellitus. (1993) (17)
Toward clinical trials of islet xenotransplantation (2003) (17)
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets. (2010) (17)
Clostripain, the Missing Link in the Enzyme Blend for Efficient Human Islet Isolation (2015) (17)
Glucose Effectiveness: The Mouse Trap in the Development of Novel ß-Cell Replacement Therapies (2016) (17)
DNA REPLICATION IN MOUSE PANCREATIC ISLETS TRANSPLANTED SUBCAPSULARLY INTO THE KIDNEY OR INTRAPORTALLY INTO THE LIVER (1990) (17)
Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post‐transplantation period (2005) (16)
Efficacy of immunosuppressive drugs in islet xenotransplantation: A study in the pig‐to‐rat model (1995) (16)
The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass (2018) (16)
Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials (2013) (16)
Reinnervation of transplanted pancreatic islets: a comparison between islets implanted into the kidney, spleen, or liver. (1992) (16)
Microbiological characterization of porcine fetal islet‐like cell clusters for intended clinical xenografting (1995) (16)
Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation (2016) (15)
Mesenchymal Stromal Cells to Halt the Progression of Type 1 Diabetes? (2015) (14)
Pancreatic perfusion and subsequent response to glucose in healthy individuals and patients with type 1 diabetes (2016) (14)
The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro (2009) (14)
Effects of Culture Conditions on Formation and Hormone Content of Fetal Porcine Isletlike Cell Clusters (1989) (14)
Pig-to-human islet transplantation. (1998) (14)
Gene expression analysis of human islets in a subject at onset of type 1 diabetes (2014) (14)
Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process (2002) (14)
Xenoislet rejection following pig-to-rat, pig-to-primate, and pig-to-man transplantation. (1996) (14)
Soluble complement receptor 1 (TP10) preserves adult porcine islet morphology after intraportal transplantation into cynomolgus monkeys. (2001) (14)
Interleukin-6 in islet xenograft rejection (2001) (13)
Role of macrophages and natural killer cells in the rejection of pig islet xenografts in mice. (2000) (13)
Reinnervation of transplanted fetal porcine endocrine pancreas. Evidence for initial growth and subsequent degeneration of nerve fibers in the islet grafts. (1996) (13)
Photochemical pathogen inactivation of human serum enables its large‐scale application in clinical cell transplantation (2010) (13)
Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/− Mice (2010) (13)
Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study (2020) (13)
Immune response of diabetic patients against transplanted porcine fetal islet cells. (1992) (13)
REINNERVATION OF SYNGENEIC PANCREATICO-DUODENAL GRAFTS IN RATS1 (2001) (13)
Pig-to-human islet transplantation in eight patients. (1994) (13)
Delayed type hypersensitivity‐associated cytokines in islet xenotransplantation: limited efficacy of interleukin‐2‐ and tumor necrosis factor‐α‐blockade in interferon‐γ receptor‐deficient mice (2000) (13)
The effect of truncated collagenase class I isomers on human islet isolation outcome. (2010) (12)
No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes. (2018) (12)
Specificity of human xenoantibodies formed in response to fetal porcine isletlike cell clusters. (1994) (12)
Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer (2018) (12)
Transplantation of porcine fetal islet-like cell clusters to three diabetic patients. (1992) (12)
Islet allo- and xenotransplantation in normal, intercellular adhesion molecule-1-deficient, and P selectin-deficient mice. (1997) (12)
Deoxyspergualin delays xenograft rejection in the guinea pig-to-C6-deficient rat heart transplantation model (1999) (12)
Aspects of pancreatic islet transplantation in diabetes mellitus. (1989) (12)
Triple drug treatment with cyclosporine, leflunomide and mycophenolate mofetil prevents rejection of pig islets transplanted into rats and primates. (1997) (12)
Perfluorohexyloctane improves long‐term storage of rat pancreata for subsequent islet isolation (2009) (12)
Cost and clinical outcome of islet transplantation in Norway 2010‐2015 (2017) (11)
Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells (2019) (11)
The recent finding that tissue factor is produced by the pancreatic islets constitutes a possible link between insulin resistance and cardiovascular disease. (2005) (11)
Mesoscopic 3D imaging of pancreatic cancer and Langerhans islets based on tissue autofluorescence (2020) (11)
Endovascular Method for Transplantation of Insulin-Producing Cells to the Pancreas Parenchyma in Swine (2014) (11)
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? (2014) (10)
Microbiologic screening as a preparatory step for clinical xenografting of porcine fetal islet-like cell clusters. (1992) (10)
Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs. (2016) (10)
Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4 (2017) (10)
15-Deoxyspergualin prolongs pancreatic islet allo- and xenograft survival in mice. (1993) (10)
Degraded collagenase deteriorates islet viability. (2008) (10)
Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography. (2011) (10)
Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells. (1996) (10)
Maturation of in vitro-generated human islets after transplantation in nude mice (2007) (10)
An Apparent Deficiency of Lymphatic Capillaries in the Islets of Langerhans in the Human Pancreas (2016) (10)
Ex vivo propagation and characterization of lymphocytes from rejecting rat-kidney allografts. (1999) (10)
Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans. (2014) (9)
Adenovirus-Mediated Expression of the Anticoagulant Hirudin in Human Islets: A Tool to Make the Islets Biocompatible to Blood (2006) (9)
Characterization of the endocrine pancreas in Type 1 Diabetes: islet size is maintained but islet number is markedly reduced (2018) (9)
Comparison of Neutral Proteases and Collagenase Class I as Essential Enzymes for Human Islet Isolation (2015) (9)
Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis (2017) (9)
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study (2021) (9)
Intragraft cytokine mRNA expression in rejecting and non‐rejecting vascularized xenografts (2003) (9)
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation (Xenotransplantation 15, 225-234) (2008) (9)
Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass. (2019) (9)
Characterization of host defense molecules in the human pancreas (2019) (9)
Persistent impairment of the insulin response to glucose both in vivo and in vitro after streptozotocin exposure: studies with grafted pancreatic islets and islets maintained in culture. (1989) (9)
A new in vitro model for the study of pig‐to‐human vascular hyperacute rejection (2001) (8)
A vast amount of enzyme activity fails to be absorbed within the human pancreas: implications for cost-effective islet isolation procedures. (2013) (8)
Human islet isolation processing times shortened by one hour: minimized incubation time between tissue harvest and islet purification. (2013) (8)
Experience with human islet transplantation in Sweden. (2001) (8)
Quantification of lymphocytes propagating from rat-kidney allografts--a tool to monitor anti-rejection treatment. (2002) (8)
Digital image analysis of islet samples yields consistent, reproducible results (2007) (8)
C-Peptide Determinations in Islet Xenotransplantation: A Study in the Pig-to-Mouse Model (2001) (8)
Transcriptional analysis of islets of Langerhans from organ donors of different ages (2021) (8)
New class of oxygen carriers improves islet isolation from long-term stored rat pancreata. (2008) (8)
Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation (2017) (8)
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets (2022) (8)
Pig Pancreas Oxygenation at 20°C Increases Islet ATP Generation but Deteriorates Islet Function (2009) (7)
Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas. (2018) (7)
Experimental pancreatic transplantation in diabetes. (1988) (7)
Aetiology of type 1 diabetes: Physiological growth in children affects disease progression (2018) (7)
Evidence of xenograft function in a diabetic patient grafted with porcine fetal pancreas. (1992) (7)
Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro (2015) (7)
Characterization of CMVpp65-Specific CD81 T Lymphocytes Using MHC Tetramers in Kidney Transplant Patients and Healthy Participants. Transplantation 2000; 69: 2243. (2000) (7)
Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function (2020) (7)
Utilization of small pediatric donors including infants for pancreas and kidney transplantation: exemplification of the surgical technique and the surveillance. (2014) (6)
INJECTION OF XENOGENEIC ENDOCRINE PANCREATIC TISSUE INTO THE PORTAL VEIN—EFFECTS ON COAGULATION, LIVER FUNCTION, AND HEPATIC HEMODYNAMICS: A STUDY IN THE PIG‐TO‐DOG MODEL1 (1992) (6)
Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs. (2012) (6)
Antisense NF-kappaB p65 prolongs experimental allo- and xenograft survival. (2001) (6)
3D imaging of human organs with micrometer resolution - applied to the endocrine pancreas (2021) (6)
The Efficacy of CD40 Ligand Blockade in Discordant Pig-to-Rat Islet Xenotransplantation Is Correlated with an Immunosuppressive Effect of Immunoglobulin (2005) (6)
Reinnervation of transplanted mouse pancreatic islets. (1991) (6)
Quantifying the Effects of Different Neutral Proteases on Human Islet Integrity (2017) (6)
IMPORTANCE OF THE GAL &agr;1–3 GAL ANTIGEN IN DISCORDANT ISLET XENOTRANSPLANTATION: IMMUNOSUPPRESSION, WHICH INHIBITS PORCINE ISLET XENOGRAFT REJECTION IN ORDINARY MICE, IS EQUALLY EFFECTIVE IN GAL-KNOCKOUT MICE (2004) (6)
Evidence of a negative feedback system regulating the total beta-cell volume in nondiabetic rats that received pancreas transplants. (1998) (6)
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids (2016) (6)
The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model (2015) (6)
On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes (2019) (6)
Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence (2019) (6)
Experience with 450 adult porcine islet isolation procedures. (2001) (6)
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT. (2018) (6)
Suppression of T cells results in long‐term survival of mouse heart xenografts in C6‐deficient rats (2001) (6)
Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver. (2015) (6)
Teplizumab in Relatives at Risk for Type 1 Diabetes. (2019) (6)
Erratum. National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418–3428 (2017) (6)
Possible Transmission of Zoonoses in Xenotransplantation: Porcine Endogenous Retroviruses (PERVs) from an Immunological Point of View (2004) (5)
Imagining a better future for all people with type 1 diabetes mellitus (2019) (5)
Longitudinal Assessment of 11C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes (2021) (5)
Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues (2021) (5)
FK 506 prevents islet xenograft rejection: a study in the pig-to-rat model. (1999) (5)
Porcine islets of langerhans isolated from normal and hDAF transgenic pigs elicit the same acute inflammatory reaction during exposure to human blood; inhibition of the response with soluble complement receptor 1 and heparin. (2000) (5)
Morphologic identification of porcine islet cells three weeks after transplantation into a diabetic patient. (1994) (5)
Experimental Studies of Transplantation and Regeneration of Endocrine Pancreatic Cells (1985) (5)
Graft function 1 year after pregnancy in an islet‐transplanted patient (2015) (5)
Xenograft Rejection of Fetal Porcine Islet-Like Cell Clusters in Normal, T-Cell Receptor β-, δ-, β × δ-; Perforin-; or Granzyme B-Deficient Mice (1998) (5)
Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1. (2020) (5)
Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation (2018) (5)
Tissue Culture and Cryopreservation of Fetal Mammalian Endocrine Pancreas Intended for Transplantation (1988) (5)
Perivascular Macrophages Regulate Blood Flow Following Tissue Damage (2021) (5)
Pre-transplantation 31P-magnetic resonance spectroscopy for quality assessment of human pancreatic grafts - A feasibility study. (2017) (5)
FTY720 in combination with CsA inhibits islet xenograft rejection: a study in the pig-to-rat model. (2000) (5)
Islets for Research: Nothing Is Perfect, but We Can Do Better (2019) (5)
US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory? (2021) (5)
Whole pancreatic and islet blood flow after syngeneic pancreaticoduodenal transplantation in the rat. (1992) (5)
Autologous regulatory T cells in clinical intraportal allogenic pancreatic islet transplantation (2021) (5)
Immunosuppression with leflunomide and cyclosporine prevents pig-to-rat islet xenograft rejection. (1995) (4)
Proceedings of “Pig‐to‐Man Islet Transplant Summit” held at the Nobel Forum, Stockholm, June 4–5, 2007 (2008) (4)
Immunosuppression with cyclosporin A in combination with leflunomide and mycophenolate mofetil prevents rejection of pig-islets transplanted into rats. (1996) (4)
Lymphocyte propagation from biopsies of kidney allografts. (2006) (4)
Clinical Islet Xenotransplantation - Transplantation of Porcine Islets into Diabetic Patients (1997) (4)
The role of vitamin D in the aetiology of type 1 diabetes (2020) (4)
Cyclosporine induces long-term xenograft survival in the mouse-to-C6-deficient rat heart transplantation model. (2000) (4)
Proton MR spectroscopy of human pancreas allografts (2019) (4)
Functional maturation of fetal porcine isletlike cell clusters after transplantation into nude mice. (1990) (4)
PET-CT imaging of pulmonary inflammation using [68Ga]Ga-DOTA-TATE (2022) (4)
Completion of the first FDA phase 3 multicenter trial of Islet transplantation in type 1 diabetes by the NIH CIT consortium (2014) (4)
THE NORDIC NETWORK FOR CLINICAL ISLET TRANSPLANTATION - ISLET AFTER KIDNEY (IAK) - RESULTS AND EXPERIENCES FROM THE FIRST 44 TRANSPLANTATIONS. (2004) (4)
Characterization of natural and induced human xenophile antibodies before and after transplantation of the fetal porcine endocrine pancreas. (1994) (4)
Effects of cyclosporin A on the blood flow of the native and transplanted rat pancreas and duodenum (1993) (4)
Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism (2018) (4)
Syngeneic islet transplantations into the submandibular gland of mice. (2011) (4)
A Consensus Document based on the Pig‐to‐Man Islet Transplant Summit held in Stockholm, June 4–5, 2007 (2008) (4)
Protein Kinase R Is Constitutively Expressed in the Human Pancreas (2018) (4)
DNA replication in pancreatic islets and adrenals in diabetic Chinese hamsters. (1993) (4)
INFLAMMATORY MEDIATORS EXPRESSED IN HUMAN ISLETS OF LANGERHANS: IMPLICATIONS FOR THE DEVELOPMENT OF AUTOIMMUNITY AND FOR ISLET TRANSPLANTATION1: 028 (2003) (4)
Influence of persistent hyperglycemia on transplanted pancreatic islets. (1990) (4)
Membrane Protein Profiling of Human Islets of Langerhans Using Several Extraction Methods (2010) (4)
Title: Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes Short running title: Enterovirus in pancreas in patients with T1D (2014) (4)
Xenograft rejection of fetal porcine islet-like cell clusters in normal, T-cell receptor beta-, delta-, beta x delta-; perforin-; or granzyme B-deficient mice. (1998) (3)
Title : The Positron Emission Tomography ligand [ 11 C ] 5-Hydroxy-Tryptophan can be used as a surrogate marker for the human endocrine pancreas (2014) (3)
TECHNICAL IMPROVEMENT OF HUMAN PANCREATIC ISLET ISOLATION (2004) (3)
Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69 (2021) (3)
Imaging the in vivo fate of human T cells following transplantation in immunoincompetent mice - implications for clinical cell therapy trials. (2013) (3)
Complement regulatory proteins on human and porcine nontransgenic and hDAF transgenic islet cells: expression and role in susceptibility to lysis by human serum. (2000) (3)
Engraftment of isolated islets after syngeneic transplantation into normal and diabetic mice. (1992) (3)
Pancreatic islet transplantation in the human. (1993) (3)
Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas–Long-Term Follow Up (2021) (3)
Corrigendum to "Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs" [Nucl Med Biol 43 (2016) 397-402]. (2016) (3)
Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation (2012) (3)
Immunogenicity of Hanganutziu-Deicher antigens in pig-to-human xenotransplantation. (2000) (3)
Lack of Systemic Anaphylaxis and Aeroallergen–Induced Airway Plasma Extravasation in Allergic Immunoglobulin–Deficient Mice (1999) (3)
Transfer of immunocompetent cells to athymic nude mice previously transplanted with fetal porcine islet-like cell clusters. (1997) (3)
Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation (2016) (3)
The CD4+ effector cell in islet xenotransplantation is a macrophage and not a T-lymphocyte. (1995) (3)
Technical improvement of human pancreatic islet isolation. (2005) (3)
Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection. (1995) (3)
Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes (2021) (3)
Treating diabetes with islet transplantation: Lessons learnt from the Nordic network for clinical islet transplantation (2020) (2)
PET Imaging of GPR44 by Antagonist [11C]MK-7246 in Pigs (2021) (2)
A novel model for studies of blood-mediated long-term responses to cellular transplants (2015) (2)
Brequinar in combination with cyclosporine a inhibits islet xenograft rejection for up to 24 days: a study in the pig-to-rat model. (2000) (2)
Adenovirus CD 40 Ligand Gene Therapy Counteracts Immune Escape Mechanisms in the Tumor Microenvironment 1 (2004) (2)
Transplantation of discordant xenogeneic endocrine pancreatic cell clusters into the liver: effects on coagulation, liver function, and hepatic hemodynamics. A safety study in the pig to dog model. (1992) (2)
Assessment of intrahepatic islet of Langerhans transplantation with dynamic Ga-68-NODAGA-exendin PET imaging (2019) (2)
Xenotransplanting Pancreatic Islets (2001) (2)
Xenotransplantation of fetal porcine islet-like cell clusters in diabetes mellitus : an experimental and clinical study (1991) (2)
Effects of immunosuppressive drugs on human islet neogenesis in vitro (2006) (2)
CART is upregulated in islets of type 2 diabetic patients, stimulates insulin secretion, inhibits glucagon secretion and protects against beta cell death (2010) (2)
Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea‐pig hearts in macrophage‐depleted C6‐deficient rats (2003) (2)
Washout kinetics of blood cells from the perfused pancreas of normoglycemic and diabetic rats. (1994) (2)
Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334–1345 (2017) (2)
Efficacy of malononitriloamide 279 and 715 in islet xenotransplantation: a study in the pig-to-rat model. (2000) (2)
Low molecular weight dextran sulfate abrogates the instant blood‐mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo: 067 (2003) (2)
Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter] (2017) (2)
Decreased defluorination using the novel beta- cell imaging agent ( 18 F)FE-DTBZ-d4 in pigs (2011) (2)
Interleukin‐6 in islet xenograft rejection (2001) (1)
Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism (2020) (1)
The importance of the Gal??1-3Gal antigen in islet xenotransplantation: Immunosuppression that inhibits porcine islet xenograft rejection in Gal+ mice is equally effective in Gal- mice (1998) (1)
Metabolic characteristics of fetal porcine islet-like cell clusters intended dfor transplantation (1992) (1)
Commercial Enzymes for Islet Isolation : Integrity and Degradation Over Time and Temperature (2013) (1)
PET Imaging of Neutrophil Elastase with 11C-GW457427 in Acute Respiratory Distress Syndrome in Pigs (2022) (1)
DISTRIBUTION OF THE Gala1–3Gal ANTIGEN IN CULTURED ADULT AND FETAL PORCINE PANCREATIC ISLET CELLS: AN IMMUNOELECTRON MICROSCOPIC STUDY (2000) (1)
Degraded collagenase deteriorates islet viability and posttransplant function (2007) (1)
Islet Transplantation & β-Cell Replacement Therapies for Diabetes (2012) (1)
Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy : A Case Report (2017) (1)
Co‐transplantation of human and pig islets (2008) (1)
The Amphiphilic Oxygen Carrier Perfluorohexyloctane Improves Oxygenation of Ischemic Pig Pancreases and Increases the Quality of Isolated Islets Compared to Perfluorodecalin (2012) (1)
Altered microvasculature in pancreatic islets from subjects with type 1 diabetes (2022) (1)
Pancreatic uptake of [68Ga]DO3A-Exendin4 is mediated by the GLP-1 receptor (2012) (1)
Cellular therapies in preclinical and clinical islet transplantation: Mesenchymal stem cells (2020) (1)
Dynamics of porcine endogenous retrovirus expression after fetal islet xenotransplantation to athymic and normal rats (2004) (1)
A new class of oxygen carriers improves successful islet isolation from long-term stored rat pancreata (2007) (1)
SOLUBLE COMPLEMENT RECEPTOR 1 (TP10) PRESERVES ADULT PORCINE ISLETS MORPHOLOGY AFTER INTRAPORTAL TRANSPLANTATION INTO CYNOMOLGUS MONKEYS.: Abstract# 1177 (2000) (1)
TACROLIMUS PREVENTS ISLET XENOGRAFT REJECTION: A STUDY IN THE PIG-TO-RAT MODEL (1998) (1)
A New Model for the Study of Vascular Hyperacute Rejection in Xenotransplantation. (1998) (1)
Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide. (2017) (1)
Protective effect of FK-506 in pig-to-rat islet xenotransplantation is abrogated by prednisolone. (2000) (1)
DISTRIBUTION OF THE Gal&agr;1–3Gal ANTIGEN IN CULTURED ADULT AND FETAL PORCINE PANCREATIC ISLET CELLS: AN IMMUNOELECTRON MICROSCOPIC STUDY1 (2000) (0)
Calcium (2018) (0)
Expanding the Donor Pool in Islet Transplantation : Age Impacts Parameters Regulating Glucose Metabolism (2013) (0)
A new oxygen carrier improves human islet isolation outcome after prolonged cold storage (2009) (0)
Identification of potential circulating beta cell biomarkers (2015) (0)
Enterovirus Infection Induces IP-10/CXCL10 Expression and Secretion from Human Pancreatic Islets in vitro (2005) (0)
Functional restoration of tissue perfusion by strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb (2013) (0)
Immmunological characteristics of the protective effect of FK506 in islet xenotransplantation (2001) (0)
Synthesis and initial preclinical evaluation of the CRTH2 antagonist [C-11] MK-7246 (2019) (0)
Immunosuppression in dopamine producing neural cell xenotransplantation: A study in the pig-to-rat model (1999) (0)
New use in the Transplantationsschirugie (2000) (0)
Ongoing Pathogenic Processes in the Pancreas at Onset of Type 1 Diabetes in Humans (2013) (0)
Evaluation of the new pancreas preservation solution, I-Let Protect, for clinical islet isolation and transplantation (2015) (0)
MONITORING CELLULAR IMMUNITY AFTER KIDNEY TRANSPLANTATION: THE IMMUKNOW(®) ASSAY DOES NOT PROPERLY REFLECT CHANGES IN T CELL REACTIVITY: 111 (2008) (0)
PET imaging of lung inflammation in pig by neutrophil elastase inhibitor [11C]GW457427 (2022) (0)
5th European Transplant Fellow Workshop (2004) (0)
A NEW CLASS OF OXYGEN CARRIERS IMPROVES LONG-TERM STORAGE OF PORCINE AND HUMAN PANCREATA FOR SUBSEQUENT ISLET ISOLATION: 160 (2008) (0)
Human islet purification utilizing a semi-closed automated pump system (2007) (0)
LYMPHOCYTE PROPAGATION FROM BIOPSIES OF KIDNEY ALLOGRAFTS. CORRELATION TO MORPHOLOGICAL DIAGNOSIS AND THE CLINICAL OUTCOME. (2006) (0)
TREATMENT WITH ANAKINRA AND TOCILIZUMAB REDUCE THE PRO-INFLAMMATORY RESPONSE AND ENHANCES ISLET SURVIVAL AND FUNCTION IN HUMAN ISLETS DURING CULTURE: IMPLICATIONS FOR CLINICAL ISLET TRANSPLANTATION.: 1623 (2010) (0)
CONCURRENT SESSION 96: CLINICAL AND EXPERIMENTAL ISLET TRANSPLANTATION II (2006) (0)
Enterovirus-induced disintegration of human pancreatic islets, but not viral replication per se, reduces beta cell function selectively (2012) (0)
BRIEF GLUCOCORTICOID EXPOSURE TO HUMAN PANCREATIC ISLETS IN VITRO SUPPRESSES TISSUE FACTOR EXPRESSION AND DO NOT INDUCE LONG-TERM ADVERSARY EFFECT ON INSULIN SECRETION. (2006) (0)
Imaging of fibrosis in metabolic associated liver disease by a radiolabeled affibody targeting PDGFRB (2022) (0)
COATING OF PANCREATIC ISLETS WITH ENDOTHELIAL CELLS PRIOR TO ISLET TRANSPLANTATION: A NEW APPROACH TOWARDS IMMUNOLOGICAL PROTECTION IN THE EARLY POST TRANSPLANTATION PERIOD. (2004) (0)
Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle (670.6) (2014) (0)
[Replacement therapy with beta-cells: the way to treat diabetes in the future?]. (2004) (0)
FTY720 PLUS CsA INHIBITS PORCINE ISLET XENOGRAFT REJECTION IN RATS FOR UP TO 24 DAYS.: Abstract# 553 Poster Board #‐Session: P191‐II (2000) (0)
Expression of Coxsackie and Adenovirus Receptor in islets of Langerhans from Type 1 diabetes, islet autoantibody positive and non-diabetic subjects (2013) (0)
RANTES/CCL5 secretion during enterovirus infection of isolated human pancreatic islets and human islets derived-cells (2006) (0)
Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis (2017) (0)
Counteracts Immune Escape Mechanisms in Adenovirus CD40 Ligand Gene Therapy (2004) (0)
MONITORING CELLULAR IMMUNITY IN THE TREATMENT OF BK VIRUS INFECTION AFTER KIDNEY TRANSPLANTATION: TWO CASE REPORTS: 1367 (2008) (0)
MUSCLE SPECIFIC CYTOKINE RESPONSES TO INTRAMUSCULAR TRANSPLANTATION PROCEDURE WITH ANTI-INFLAMMATORY EFFECTS OF IL-1ß AND IL-6 RECEPTOR BLOCKADE.: 1678 (2010) (0)
Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion (2013) (0)
In Human Islets the Intracellular Concentration of Sirolimus Diminish when Combined with Tacrolimus, In Vitro. (2013) (0)
Acute cellular islet xenograft rejection in MyD88-deficient mice (2004) (0)
Enzymes for human islet isolation - Which components do we need? (2007) (0)
Critical factors for the endocrine differentiation of cultured adult human ductal cells (2001) (0)
Enterovirus Infection Reduces Beta-cell Function and Leads to Decreased Glucose Stimulated Insulin Secretion in Dissociated but not In Intact Pancreatic Human Islets (2013) (0)
Transplantable functional islet mass – predictive biomarkers of graft function in islet after kidney transplanted patients (2011) (0)
Proof of concept for the clinical application of animal component free recombinant collagenase for isolating pancreatic islets (2015) (0)
PET imaging of the GLP-1 receptor in healthy and streptozotocin-induced diabetic pigs (2014) (0)
ADENOVIRUS-MEDIATED EXPRESSION OF THE ANTI-COAGULANT HIRUDIN IN HUMAN PANCREATIC ISLETS. (2004) (0)
Ultrastructural identification of cells expressing Galalpha1-3Gal antigen in cultured fetal porcine isletlike cell clusters. (2000) (0)
Development of peptide probes for imaging of CD206 positive macrophages in cancer (2022) (0)
Low molecular weight dextran sulfate unlike heparin abrogates the instant blood-mediated inflammatory reaction in pig-to-monkey pre-clinical islet xenotransplantation (2005) (0)
Proceedings of "Pig-to-Man Islet Transplant Summit" - Stockholm, June 4-5 2007 - Opening remarks (2008) (0)
ELEVATED EXPRESSION OF MCP-1 AND TISSUE FACTOR IN PANCREATIC TISSUE CORRELATES TO TIME AT THE INTENSIVE CARE UNIT: POSSIBLE IMPLICATIONS FOR THE OUTCOME OF ISLET TRANSPLANTATION. (2004) (0)
CMV-specific T-helper cell responses are delayed in infants with congenital CMV compared to adults with primary infection. (2008) (0)
OPTIMISING HUMAN SERUM FOR CLINICAL ISLET ISOLATION: 1319 (2008) (0)
National of Health– Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities (2017) (0)
THE IMPORTANCE OF TRYPTIC-LIKE ACTIVITIES FOR HUMAN ISLET ISOLATION: 766 (2008) (0)
Experimental and clinical experience with xenoislet transplantation. (1996) (0)
Functional Imaging of the Pancreatic Graft by Positron Emission Tomography (2013) (0)
Multicenter Assessment of Animal-free Collagenase AF1 for Human Islet Isolation BRANDHORST (2018) (0)
Predicting the outcome of human islet isolation (2011) (0)
Tribute to Carl-Gustav Groth (1933-2014), first president of the International Xenotransplantation Association. (2014) (0)
Present State of Islet Transplantation for Type 1 Diabetes Patients (2011) (0)
Xenograft rejection of fetal porcine islet-like cell clusters inreceptor beta-, delta-, beta x delta-; perforin-; orient mice. (1998) (0)
Adult porcine, but not rat, islets fail to cure diabetic athymic mice when transplanted via the portal vein (2003) (0)
Increased glucagon content in the endocrine pancreas in recent onset type 1 diabetes. Results from the DiViD study. (2016) (0)
Porcine islets of langerhans isolated from normal and hDAF transgenic pigselicit the same acute inflammatory reaction during exposure to humanblood; inhibition of the response with soluble complement (2000) (0)
Use of dextran sulfate for treatment of IBMIR (2003) (0)
Uncovering a new role for immune cells : macrophages assist in regulation of blood flow in ischemic muscle (2016) (0)
Engineering Regulatory Cells With a T Cell Receptor for Controlled Activation (2014) (0)
Nicotinamide suppresses the expression and producfion of tissue factor in human islets: 0105 (2003) (0)
MONITORING VIRUS SPECIFIC T CELLS MAY IMPROVE THE MANAGEMENT OF IMMUNOSUPPRESSION AFTER LIVER TRANSPLANTATION: 361 (2008) (0)
In Vitro Effects of Clinical Immunosuppressive Regimens on Human Islet Function and Apoptosis Are Dependent on Doses: 1290 (2012) (0)
SHORT-TERM INFUSION OF LOW MOLECULAR WEIGHT DEXTRAN SULFATE (LMW-DS) IS WELL TOLERATED IN HUMANS AND INCREASES ENDOGENOUS EXPRESSION OF ISLET PROTECTIVE HEPATOCYTE GROWTH FACTOR (HGF): 1315 (2008) (0)
Coxsackievirus B3 induces the mRNA expression of IFNbeta and viral recognition receptors in human pancreatic islets (2010) (0)
Exendin-4 Decreases Blood Glucose Levels, but Does not Affect Other Metabolic Parameters in Transplanted Human Islets from Old and Young Donors: 1040 (2012) (0)
Cocaine- and amphetamine-regulated transcript (CART) is upregulated in islets of type-2 diabetic patients to stimulate insulin secretion, inhibit glucagon secretion and protect against beta cell death (2010) (0)
Ga-68-labelling of Exendin-4, preclinical evaluation of the resultant tracer for the imaging and quantification of insulinomas, and case patient examination (2013) (0)
Neural Crest Stem Cells Induce Beta-cell Proliferation in Cultured and Transplanted Human Pancreatic Islets (2013) (0)
Different effects of neutral proteases on human islet viability (2016) (0)
One-layer method with novel compound perfluorohexyloctane increases levels of ATP relative to perfluorodecalin as shown by 31P-NMR spectroscopy (2009) (0)
CD40L immunogene therapy of cancer counteracts IL10 induced anergy (2002) (0)
Preliminary Results From Evaluation of an Innovative, Closed, Automated, Continuous Media Renewal System for Human Islets of Langerhans (2013) (0)
Rapid Destruction of Porcine Islets of Langerhans by Fresh Human Blood. (1998) (0)
Low molecular weight dextran sulfate abrogates the allogeneic instant blood-mediated inflammatory reaction (IBMIR); A strong candidate drug to improve clinical islet transplantation (2006) (0)
Title Minimum Information about T Regulatory Cells : A Step toward Reproducibility and Standardization Permalink (2018) (0)
IMMUNOSUPPRESSION WITH CsA, MMF AND LEFLUNOMIDE PREVENTS REJECTION FOR UP TO 100 DAYS AFTER ADULT PORCINE ISLET XENOTRANSPLANTATION INTO DIABETIC RATS.: Abstract# 551 Poster Board #‐Session: P189‐II (2000) (0)
Comparison of liberase HI and collagenase NB1 in 199 human islet isolations (2009) (0)
Evaluation of a newly developed pancreas preservation solution, F6H8S5, for clinical islet isolation and transplantation (2016) (0)
New perspectives on the structure and function of the normal and diabetic beta-cell. (1991) (0)
[18F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44 (2023) (0)
Immunosuppressive Drugs Show No Adverse Effects on MSCCoated Islets In Vitro: 1289 (2012) (0)
Erratum (1926) (0)
Assessing the Viability of Human Pancreas Grafts using 31P MR Spectroscopy - a Pilot Study (2013) (0)
Effects of Neutrophil Elastase Inhibitor on Progression of Acute Lung Injury After Liver Transplantation (2018) (0)
Islet xenotransplantation for insulin dependent diabetes mellitus. (1995) (0)
Evaluation of Affibody molecule Z09591 for PET imaging in fibrosis (2022) (0)
Expression and function of lutheran, a laminin alpha5 binding glycoprotein receptor on human pancreatic islet cells (2008) (0)
Characterization of the instant blood-mediated inflammatory reaction in clinical hepatocyte transplantation and identification of LMW-DS as a tentative treatment (2012) (0)
Opening remarks (2008) (0)
Validity of urinary C-peptide determinations in xenogeneic islet transplantation. (1994) (0)
BOTH THE CYTOKINE PROFILE AND THE CELLULAR INFILTRATION IN ACUTE CELLULAR XENOGRAFT REJECTION RESEMBLES THAT OF A DTH REACTION.: Abstract# 552 Poster Board #‐Session: P190‐II (2000) (0)
Erratum. Direct Substrate Delivery Into Mitochondrial Fission–Deficient Pancreatic Islets Rescues Insulin Secretion. Diabetes 2017;66:1247–1257 (2017) (0)

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