Oluf Borbye Pedersen
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Oluf Borbye Pedersen's Degrees
- PhD Biochemistry University of Copenhagen
- Masters Molecular Biology University of Copenhagen
- Bachelors Biology University of Copenhagen
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(Suggest an Edit or Addition)Oluf Borbye Pedersen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A human gut microbial gene catalogue established by metagenomic sequencing (2010) (9177)
- Enterotypes of the human gut microbiome (2011) (4920)
- A metagenome-wide association study of gut microbiota in type 2 diabetes (2012) (4798)
- Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. (2003) (4290)
- Richness of human gut microbiome correlates with metabolic markers (2013) (3351)
- Effect of a multifactorial intervention on mortality in type 2 diabetes. (2008) (3152)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
- Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes (2008) (1882)
- The Human Intestinal Microbiome in Health and Disease. (2016) (1877)
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2010) (1801)
- Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) (1996) (1567)
- An integrated catalog of reference genes in the human gut microbiome (2014) (1431)
- Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity (2009) (1344)
- Human gut microbes impact host serum metabolome and insulin sensitivity (2016) (1257)
- Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota (2015) (1243)
- Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
- Gut microbiota in human metabolic health and disease (2020) (1116)
- A variant in CDKAL1 influences insulin response and risk of type 2 diabetes (2007) (1066)
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (1028)
- Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study (1999) (946)
- The genetic architecture of type 2 diabetes (2016) (927)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
- Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes (2014) (812)
- Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes (2007) (765)
- The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm (2008) (765)
- SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations (2008) (717)
- Enterotypes of the human gut microbiome (2011) (713)
- NetMHCpan, a method for MHC class I binding prediction beyond humans (2008) (675)
- Many sequence variants affecting diversity of adult human height (2008) (664)
- High Prevalence of Type 2 Diabetes and Pre-Diabetes in Adult Offspring of Women With Gestational Diabetes Mellitus or Type 1 Diabetes (2008) (638)
- A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk (2009) (574)
- An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans (2017) (547)
- The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
- Low Physical Activity Accentuates the Effect of the FTO rs9939609 Polymorphism on Body Fat Accumulation (2008) (522)
- Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin. (1995) (521)
- Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution (2007) (515)
- Rare and low-frequency coding variants alter human adult height (2016) (511)
- Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children (2011) (508)
- Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia (2009) (452)
- [The genetics of obesity]. (2006) (450)
- Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
- Metagenomic species profiling using universal phylogenetic marker genes (2013) (421)
- Loss-of-function mutations in SLC30A8 protect against type 2 diabetes (2014) (405)
- Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes. (2009) (384)
- Disentangling the effects of type 2 diabetes and metformin on the human gut microbiota (2015) (383)
- Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials (2016) (379)
- Recovery of gut microbiota of healthy adults following antibiotic exposure (2018) (372)
- Genome-wide associations for birth weight and correlations with adult disease (2016) (371)
- Evidence Against Altered Expression of GLUT1 or GLUT4 in Skeletal Muscle of Patients With Obesity or NIDDM (1990) (370)
- Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial (2016) (369)
- Greenlandic Inuit show genetic signatures of diet and climate adaptation (2015) (363)
- Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci (2015) (349)
- Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus (2001) (330)
- Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants (2010) (322)
- Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus (1993) (313)
- A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes (2014) (305)
- New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism (2012) (300)
- The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes. (2003) (295)
- Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes (2014) (294)
- Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2017) (294)
- Common nonsynonymous variants in PCSK1 confer risk of obesity (2008) (288)
- Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity (2014) (287)
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation (2015) (285)
- PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study (2017) (283)
- The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population. (2005) (277)
- Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2018) (269)
- Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. (1996) (267)
- Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut (2016) (266)
- Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population. (2004) (265)
- The genetic abnormality in the beta cell determines the response to an oral glucose load (2002) (264)
- A germline variant in the TP53 polyadenylation signal confers cancer susceptibility (2011) (261)
- A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B (2010) (261)
- Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome. (2002) (256)
- Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2 Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects (2007) (246)
- A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. (1996) (245)
- Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. (2016) (245)
- The Polygenic and Monogenic Basis of Blood Traits and Diseases (2020) (242)
- Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum (2018) (242)
- New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
- Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. (2005) (241)
- Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (2016) (234)
- Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial (2017) (230)
- Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota (2016) (228)
- Aberrant intestinal microbiota in individuals with prediabetes (2018) (228)
- Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes (2001) (228)
- Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations (2020) (225)
- Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1 (1995) (224)
- GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study (2015) (221)
- Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood. (2015) (221)
- Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle. (1990) (218)
- The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype. (2003) (215)
- Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus. (2008) (214)
- Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria. (2004) (214)
- Common type 2 diabetes risk gene variants associate with gestational diabetes. (2009) (214)
- Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients. (2000) (212)
- Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4α mutations in a large European collection (2005) (211)
- Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-γ2 (PPAR-γ2): divergent modulating effects on body mass index in obese and lean Caucasian men (1999) (208)
- Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner. (2001) (206)
- Large-scale association analyses identify host factors influencing human gut microbiome composition (2020) (206)
- Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes (2009) (199)
- Genetic evidence of assortative mating in humans (2017) (199)
- Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm (2010) (197)
- Specific gut microbiota features and metabolic markers in postmenopausal women with obesity (2015) (193)
- Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
- Intake of a Diet High in Trans Monounsaturated Fatty Acids or Saturated Fatty Acids: Effects on postprandial insulinemia and glycemia in obese patients with NIDDM (1997) (188)
- Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes (2016) (187)
- Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study (2014) (187)
- Statin therapy is associated with lower prevalence of gut microbiota dysbiosis (2020) (186)
- Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility (2015) (185)
- Dietary glycemic index, glycemic load, fiber, simple sugars, and insulin resistance: the Inter99 study. (2005) (183)
- Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes (2015) (183)
- Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity. (2005) (183)
- Impaired cellular insulin binding and insulin sensitivity induced by high-fructose feeding in normal subjects. (1980) (181)
- Estimation of allele frequency and association mapping using next-generation sequencing data (2011) (179)
- Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry (2013) (178)
- Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes (2005) (174)
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. (2008) (170)
- Increased insulin receptors after exercise in patients with insulin-dependent diabetes mellitus. (1980) (169)
- Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial (2017) (167)
- Development of a Type 2 Diabetes Risk Model From a Panel of Serum Biomarkers From the Inter99 Cohort (2009) (167)
- Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond (2014) (166)
- A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. (2003) (161)
- Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) gene in relation to insulin sensitivity among glucose tolerant Caucasians (2001) (159)
- Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. (2012) (158)
- Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study (2008) (155)
- FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans. (2017) (154)
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (153)
- Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (153)
- A reference map of potential determinants for the human serum metabolome (2020) (152)
- FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. (2014) (151)
- The Trans-Ancestral Genomic Architecture of Glycemic Traits (2020) (151)
- Mechanisms in endocrinology: Gut microbiota in patients with type 2 diabetes mellitus. (2015) (150)
- Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents (2020) (149)
- Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits (2017) (149)
- Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes (2019) (148)
- Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study (2011) (148)
- Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios (2015) (148)
- Immune markers and correlates of protection for vaccine induced immune responses. (2012) (147)
- Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels (2016) (147)
- The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes (2007) (146)
- Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action (2008) (145)
- Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes (2008) (145)
- Natural Selection Affects Multiple Aspects of Genetic Variation at Putatively Neutral Sites across the Human Genome (2011) (145)
- Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide. (1979) (141)
- The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men (2009) (138)
- Genome-Wide Population-Based Association Study of Extremely Overweight Young Adults – The GOYA Study (2011) (137)
- Cost-Effectiveness of Intensified Versus Conventional Multifactorial Intervention in Type 2 Diabetes (2008) (137)
- Suppression of GLUT4 expression in skeletal muscle of rats that are obese from high fat feeding but not from high carbohydrate feeding or genetic obesity. (1993) (137)
- G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release (2009) (136)
- Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes (2016) (136)
- An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples (2016) (135)
- Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes. (2013) (134)
- Insulin Sensitivity and Body Weight Changes in Young White Carriers of the Codon 64 Amino Acid Polymorphism of the β3-Adrenergic Receptor Gene (1996) (132)
- Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes (2018) (131)
- Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes (2012) (129)
- The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
- Insulin Gene Mutations Resulting in Early-Onset Diabetes: Marked Differences in Clinical Presentation, Metabolic Status, and Pathogenic Effect Through Endoplasmic Reticulum Retention (2009) (128)
- A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference (2002) (125)
- Dietary modulation of the gut microbiota – a randomised controlled trial in obese postmenopausal women (2015) (124)
- Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects (2006) (123)
- High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats. (1991) (122)
- Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene. (1998) (121)
- The E 23 K Variant of Kir 6 . 2 Associates With Impaired Post – OGTT Serum Insulin Response and Increased Risk of Type 2 Diabetes (2003) (120)
- Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms (2014) (120)
- The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients—the EUGENE2 study (2008) (119)
- Sequencing and de novo assembly of 150 genomes from Denmark as a population reference (2017) (118)
- Pleiotropic genes for metabolic syndrome and inflammation. (2014) (118)
- Receptor‐mediated activation of gastric vagal afferents by glucagon‐like peptide‐1 in the rat (2009) (117)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (117)
- Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes. (1989) (117)
- Double‐blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients (2001) (117)
- Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis. (2004) (115)
- Genetic Architecture of Vitamin B12 and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets (2013) (115)
- Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation (2016) (114)
- Genome wide association study identifies KCNMA1 contributing to human obesity (2011) (114)
- Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes (2013) (113)
- A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene. (2004) (113)
- Autosomal dominant optic atrophy associated with hearing impairment and impaired glucose regulation caused by a missense mutation in the WFS1 gene (2005) (113)
- Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness (2017) (113)
- The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency (2001) (111)
- Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24‐h energy expenditure and substrate oxidation (1999) (110)
- Cohort Profile: the Health2006 cohort, research centre for prevention and health. (2014) (110)
- Mutations in the hepatocyte nuclear factor-1α gene in Caucasian families originally classified as having Type I diabetes (1998) (110)
- The 11q;22q translocation: A European collaborative analysis of 43 cases (2004) (109)
- Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. (2016) (108)
- A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults (2018) (107)
- GLP-1 Receptor Agonist Treatment Increases Bone Formation and Prevents Bone Loss in Weight-Reduced Obese Women. (2015) (106)
- Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations. (2008) (106)
- A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes (2018) (105)
- A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes (2011) (105)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
- Plasma N-terminal pro-brain natriuretic peptide as a major risk marker for cardiovascular disease in patients with type 2 diabetes and microalbuminuria (2004) (104)
- Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels (2017) (103)
- Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity. (2008) (103)
- Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study (2019) (101)
- Intake of macro- and micronutrients in Danish vegans (2015) (101)
- Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus. (1993) (100)
- Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease (1995) (100)
- Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes (2010) (99)
- Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus (2015) (98)
- Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants. (2015) (98)
- Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue (2009) (98)
- Erratum: Enterotypes of the human gut microbiome (Nature (2011) 473 (174-180)) (2011) (97)
- The -238 and -308 G-->A polymorphisms of the tumor necrosis factor alpha gene promoter are not associated with features of the insulin resistance syndrome or altered birth weight in Danish Caucasians. (2000) (96)
- Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people (2010) (95)
- Glut 4 content in the plasma membrane of rat skeletal muscle: comparative studies of the subcellular fractionation method and the exofacial photolabelling technique using ATB‐BMPA (1993) (95)
- Randomized, multi-center trial of two hypo-energetic diets in obese subjects: high- versus low-fat content (2006) (95)
- FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials (2016) (95)
- Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes (2009) (95)
- Novel MODY3 Mutations in the Hepatocyte Nuclear Factor-1α Gene: Evidence for a Hyperexcitability of Pancreatic β-cells to Intravenous Secretagogues in a Glucose-Tolerant Carrier of a P447L Mutation (1997) (95)
- The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians. (2000) (95)
- Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients. (1995) (94)
- Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function (2002) (94)
- The BIGTT Test (2007) (92)
- Decreased binding of insulin to its receptor in patients with congenital generalized lipodystrophy. (1977) (92)
- A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
- Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism. (2002) (92)
- Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile (2013) (92)
- Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes. (2008) (91)
- Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity. (1997) (91)
- A Single Nucleotide Polymorphism within the Acetyl-Coenzyme A Carboxylase Beta Gene Is Associated with Proteinuria in Patients with Type 2 Diabetes (2010) (90)
- Insulin resistance and impaired pancreatic β-cell function in adult offspring of women with diabetes in pregnancy. (2013) (90)
- Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study (2020) (90)
- Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis (2018) (90)
- Design of association studies with pooled or un‐pooled next‐generation sequencing data (2010) (90)
- MULTIFACTORIAL INTERVENTION AND CARDIOVASCULAR DISEASE IN PATIENTS WITH TYPE 2 DIABETES (2003) (90)
- The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway (2013) (90)
- Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation (2020) (88)
- Insulin binding and action on fat cells from young healthy females and males. (1982) (87)
- Relation between birth weight and the insulin sensitivity index in a population sample of 331 young, healthy Caucasians. (1997) (87)
- First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes (2018) (87)
- IL6 Gene Promoter Polymorphisms and Type 2 Diabetes (2006) (87)
- The gut microbiome in cardio-metabolic health (2015) (87)
- Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4α, GCK and HNF-1α (2003) (86)
- A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants (2017) (85)
- Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives (2019) (85)
- Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes: the Steno-2 study. (2003) (84)
- FTO Gene Associated Fatness in Relation to Body Fat Distribution and Metabolic Traits throughout a Broad Range of Fatness (2008) (83)
- Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. (2006) (83)
- Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial (2014) (83)
- Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits. (2017) (82)
- Analysis of the relationship between fasting serum uric acid and the insulin sensitivity index in a population-based sample of 380 young healthy Caucasians. (1998) (82)
- Melanocortin 4 receptor mutations in obese Czech children: studies of prevalence, phenotype development, weight reduction response, and functional analysis. (2007) (82)
- A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin. (1995) (81)
- Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets (2006) (81)
- Amino Acid Polymorphisms in the ATP-Regulatable Inward Rectifier Kir6.2 and Their Relationships to Glucose- and Tolbutamide-Induced Insulin Secretion, the Insulin Sensitivity Index, and NIDDM (1997) (81)
- Specificity and sensitivity of commercially available assays for glucagon‐like peptide‐1 (GLP‐1): implications for GLP‐1 measurements in clinical studies (2014) (81)
- Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes (2018) (81)
- Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion. (1993) (80)
- Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. (2002) (80)
- Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians. (1998) (79)
- Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both? (2003) (79)
- Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: Impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance (1997) (79)
- Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. (2008) (77)
- Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content. (1999) (77)
- Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. (2019) (77)
- Uncovering the Genetic History of the Present-Day Greenlandic Population (2014) (77)
- The G-allele of intronic rs 10830963 in MTNR 1 B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release : studies involving 19 , 605 Europeans (2009) (77)
- Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism (2015) (77)
- Insulin receptor binding and insulin action in human fat cells: effects of obesity and fasting. (1982) (76)
- Mechanism of Action of Sulphonylureas with Special Reference to the Extrapancreatic Effect: An Overview (1988) (76)
- Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans (2009) (75)
- Half of clinically defined maturity-onset diabetes of the young patients in Denmark do not have mutations in HNF4A, GCK, and TCF1. (2005) (75)
- Expression of GLUT1 and GLUT4 glucose transporters in skeletal muscle of humans with insulin-dependent diabetes mellitus: regulatory effects of metabolic factors. (1992) (75)
- Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology (2020) (74)
- Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study (2008) (74)
- Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes (2013) (74)
- Joint analysis of individual participants’ data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index (2009) (74)
- Diurnal profile of pancreatic polypeptide, pancreatic glucagon, gut glucagon and insulin in human morbid obesity. (1983) (74)
- Polymorphisms of Serotonin Receptor 2A and 2C Genes and COMT in Relation to Obesity and Type 2 Diabetes (2009) (74)
- Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. (2001) (73)
- Impact of a vegan diet on the human salivary microbiota (2018) (72)
- Genetics of type 2 diabetes mellitus: status and perspectives (2005) (72)
- Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis (2017) (72)
- Identification of a Common Amino Acid Polymorphism in the p85α Regulatory Subunit of Phosphatidylinositol 3-Kinase: Effects on Glucose Disappearance Constant, Glucose Effectiveness, and the Insulin Sensitivity Index (1997) (72)
- Partial and whole gene deletion mutations of the GCK and HNF1A genes in maturity-onset diabetes of the young (2007) (72)
- Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY) (2010) (72)
- Comparative effects of IGF-I and insulin on the glucose transporter system in rat muscle. (1994) (72)
- Evidence against protein kinase B as a mediator of contraction‐induced glucose transport and GLUT4 translocation in rat skeletal muscle (1998) (72)
- Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats. (1992) (72)
- Beyond the fourth wave of genome-wide obesity association studies (2012) (71)
- Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians (2009) (71)
- A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links (2018) (71)
- A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity. (2003) (71)
- Insulin Receptor Binding to Fat and Blood Cells and Insulin Action in Fat Cells from Insulin-dependent Diabetics (1982) (71)
- Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4α in Caucasians with maturity onset NIDDM (1997) (70)
- Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight (2010) (69)
- A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk. (2014) (69)
- Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites. (2004) (69)
- Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss (2014) (69)
- Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study (2015) (69)
- Impaired Expression of Glycogen Synthase mRNA in Skeletal Muscle of NIDDM Patients (1991) (68)
- Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins. (2008) (68)
- Leptin and bone mineral density: a cross-sectional study in obese and nonobese men. (2003) (68)
- Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes (2017) (68)
- Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity (1999) (68)
- PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
- Normalization of the insulin sensitivity and the cellular insulin binding during treatment of obese diabetics for one year. (1979) (67)
- Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. (2007) (66)
- Long‐term influences of body‐weight changes, independent of the attained weight, on risk of impaired glucose tolerance and Type 2 diabetes (2005) (66)
- Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease. (2001) (65)
- Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes (2009) (65)
- Diurnal variation in insulin binding to human monocytes. (1978) (65)
- A saturated map of common genetic variants associated with human height (2022) (65)
- Cohort description: The Danish study of Functional Disorders (2017) (64)
- Studies of the associations between functional β2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects (2007) (64)
- A Candidate Type 2 Diabetes Polymorphism Near the HHEX Locus Affects Acute Glucose-Stimulated Insulin Release in European Populations (2008) (64)
- A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals. (2015) (64)
- Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. (2016) (64)
- Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci (2016) (63)
- Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study (2018) (63)
- Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes (2019) (63)
- Mutational analysis of the UCP2 core promoter and relationships of variants with obesity. (2003) (63)
- Variant near ADAMTS9 Known to Associate with Type 2 Diabetes Is Related to Insulin Resistance in Offspring of Type 2 Diabetes Patients—EUGENE2 Study (2009) (63)
- Increased insulin binding to adipocytes and monocytes and increased insulin sensitivity of glucose transport and metabolism in adipocytes from non-insulin-dependent diabetics after a low-fat/high-starch/high-fiber diet. (1983) (63)
- Polymorphisms in the 3′ UTR in the neurocalcin δ gene affect mRNA stability, and confer susceptibility to diabetic nephropathy (2007) (63)
- Sequence of the Human Glycogen-Associated Regulatory Subunit of type 1 Protein Phosphatase and Analysis of Its Coding Region and mRNA Level in Muscle From Patients With NIDDM (1994) (63)
- Non-Replication of Genome-Wide Based Associations between Common Variants in INSIG2 and PFKP and Obesity in Studies of 18,014 Danes (2008) (62)
- Induction of Foot-and-Mouth Disease Virus-Specific Cytotoxic T Cell Killing by Vaccination (2010) (62)
- Expression of protein‐tyrosine phosphatases in the major insulin target tissues (1997) (61)
- Evidence of a liver–alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids (2018) (61)
- Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model (2014) (61)
- A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro. (2002) (61)
- The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas (2007) (61)
- Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes. (2005) (61)
- Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM (1994) (60)
- Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort. (2013) (60)
- Gln27Glu variant of the human beta2-adrenoreceptor gene is not associated with early-onset obesity in Danish men. (1998) (60)
- Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction (2009) (60)
- Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity (1999) (60)
- Studies of Metabolic Phenotypic Correlates of 15 Obesity Associated Gene Variants (2011) (60)
- Prednisone increases the number of insulin receptors on monocytes from normal subjects. (1980) (60)
- A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape (2016) (59)
- Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells (1998) (59)
- Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans (2016) (59)
- Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus. (2000) (58)
- Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes. (2005) (58)
- The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites (2007) (58)
- Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity. (1980) (58)
- Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function. (2002) (58)
- Association of Polymorphisms of the CHI3L1 Gene with Asthma and Atopy: A Populations-Based Study of 6514 Danish Adults (2009) (58)
- KCNQ1 Long QT Syndrome Patients Have Hyperinsulinemia and Symptomatic Hypoglycemia (2014) (58)
- Variation near the hepatocyte nuclear factor (HNF)-4α gene associates with type 2 diabetes in the Danish population (2005) (58)
- Association between neuromedin U gene variants and overweight and obesity. (2006) (57)
- Insulin receptor function and glycogen synthase activity in skeletal muscle biopsies from patients with insulin-dependent diabetes mellitus: effects of physical training. (1989) (57)
- A Prevalent Amino Acid Polymorphism at Codon 98 in the Hepatocyte Nuclear Factor-1α Gene Is Associated With Reduced Serum C-Peptide and Insulin Responses to an Oral Glucose Challenge (1997) (57)
- Aetiological heterogeneity of asymptomatic hyperglycaemia in children and adolescents (2006) (57)
- Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression (2017) (57)
- Combined Analyses of 20 Common Obesity Susceptibility Variants (2010) (56)
- The Type 2 Diabetes Associated Minor Allele of rs2237895 KCNQ1 Associates with Reduced Insulin Release Following an Oral Glucose Load (2009) (56)
- Lower-body fat mass as an independent marker of insulin sensitivity—the role of adiponectin (2005) (56)
- Obesity‐related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study (2010) (56)
- A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites. (2005) (56)
- Evidence of an association between genetic variation of the coactivator PGC-1β and obesity (2005) (56)
- TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet. (2010) (56)
- Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (55)
- Identification of the UBP1 Locus as a Critical Blood Pressure Determinant Using a Combination of Mouse and Human Genetics (2009) (55)
- Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval. (2015) (55)
- The Asn363Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men (2001) (55)
- Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene. (2005) (55)
- Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits (2020) (55)
- AHSG Tag Single Nucleotide Polymorphisms Associate With Type 2 Diabetes and Dyslipidemia (2008) (54)
- Limited impact of lifestyle education in patients with Type 2 diabetes mellitus and microalbuminuria: results from a randomized intervention study (2001) (54)
- [The Steno-2 study. Intensive multifactorial intervention reduces the occurrence of cardiovascular disease in patients with type 2 diabetes]. (2003) (54)
- Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases (2015) (54)
- Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium (2018) (54)
- Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes (2005) (53)
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
- In vivo insulin action and muscle glycogen synthase activity in Type 2 (non-insulin-dependent) diabetes mellitus: effects of diet treatment (1992) (53)
- Genetic variation in the hepatocyte nuclear factor-1a gene in Danish Caucasians with late-onset NIDDM (1997) (53)
- Progression to Impaired Glucose Regulation and Diabetes in the Population-Based Inter99 Study (2008) (53)
- Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in caucasians. (2000) (52)
- A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population. (2001) (52)
- Prostaglandin E2 receptor binding and action in human fat cells. (1984) (52)
- Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus. (2010) (52)
- Implications of Central Obesity-Related Variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on Quantitative Metabolic Traits in Adult Danes (2011) (52)
- Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation (2008) (52)
- Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early‐onset type 2 diabetes (2007) (52)
- Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release (2004) (51)
- Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish/North-European White children and adolescents (2017) (51)
- A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity. (2019) (51)
- Association of Variants in the Sterol Regulatory Element-Binding Factor 1 (SREBF1) Gene With Type 2 Diabetes, Glycemia, and Insulin Resistance (2008) (51)
- Exercise-enhanced activation of glycogen synthase in human skeletal muscle. (1990) (51)
- Combinatorial, additive and dose-dependent drug–microbiome associations (2021) (51)
- Cloning of a Human Insulin-Stimulated Protein Kinase (ISPK-1) Gene and Analysis of Coding Regions and mRNA Levels of the ISPK-1 and the Protein Phosphatase-1 Genes in Muscle From NIDDM Patients (1995) (50)
- Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people. (2007) (50)
- New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals (2017) (50)
- Increased insulin-stimulated glucose uptake in athletes: the importance of GLUT4 mRNA, GLUT4 protein and fibre type composition of skeletal muscle. (1993) (50)
- Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans (2011) (49)
- Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients With Maturity-Onset Diabetes of the Young—Type 2 and Type 3 (2014) (49)
- Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium (2014) (49)
- Fatness-Associated FTO Gene Variant Increases Mortality Independent of Fatness – in Cohorts of Danish Men (2009) (49)
- Studies of relationships between variation of the human G protein‐coupled receptor 40 Gene and Type 2 diabetes and insulin release (2005) (49)
- Leptin, adiponectin, and their ratio as markers of insulin resistance and cardiometabolic risk in childhood obesity (2019) (49)
- Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young. (2009) (49)
- Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity. (1997) (49)
- Genotype-by-nutrient interactions assessed in European obese women (2006) (49)
- The common T60N polymorphism of the lymphotoxin-α gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome (2005) (48)
- Organisation of the coding exons and mutational screening of the uncoupling protein 3 gene in subjects with juvenile-onset obesity (1998) (48)
- Transcriptional interactions suggest niche segregation among microorganisms in the human gut (2016) (48)
- Glucokinase diabetes in 103 families from a country‐based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations (2010) (48)
- A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians. (2005) (48)
- Interactions between physical activity and variants of the genes encoding uncoupling proteins −2 and −3 in relation to body weight changes during a 10-y follow-up (2005) (47)
- Obesity is associated with vitamin D deficiency in Danish children and adolescents (2017) (47)
- MTNR1B G24E Variant Associates With BMI and Fasting Plasma Glucose in the General Population in Studies of 22,142 Europeans (2010) (47)
- Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization (2018) (47)
- The FOXO3A rs2802292 G-allele associates with improved peripheral and hepatic insulin sensitivity and increased skeletal muscle-FOXO3A mRNA expression in twins. (2011) (47)
- Postreceptor Effects of Sulfonylurea on Skeletal Muscle Glycogen Synthase Activity in Type II Diabetic Patients (1989) (46)
- Elevation of Serum Insulin Concentration During Euglycemic Hyperinsulinemic Clamp Studies Leads to Similar Activation of Insulin Receptor Kinase in Skeletal Muscle of Subjects With and Without NIDDM (1995) (46)
- Validation of a Multimarker Model for Assessing Risk of Type 2 Diabetes from a Five-Year Prospective Study of 6784 Danish People (Inter99) (2009) (46)
- Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy. (2006) (46)
- A glycogene mutation map for discovery of diseases of glycosylation. (2015) (46)
- PCSK 9 genetic variants and risk of type 2 diabetes : a mendelian randomisation study (2020) (45)
- What Is the Contribution of Two Genetic Variants Regulating VEGF Levels to Type 2 Diabetes Risk and to Microvascular Complications? (2013) (45)
- Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits (2015) (45)
- Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha. (2003) (45)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
- Genotype-Phenotype Associations in Obesity Dependent on Definition of the Obesity Phenotype (2008) (45)
- Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits (2016) (45)
- Glucose tolerance status and severity of coronary artery disease in men referred to coronary arteriography. (1997) (44)
- Decreased insulin binding to monocytes from normal pregnant women. (1979) (44)
- Variation in the peroxisome proliferator-activated receptor δ gene in relation to common metabolic traits in 7,495 middle-aged white people (2007) (44)
- SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. (2017) (44)
- Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB Study (2009) (43)
- A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk (2017) (43)
- The T-Allele of TCF7L2 rs7903146 Associates With a Reduced Compensation of Insulin Secretion for Insulin Resistance Induced by 9 Days of Bed Rest (2010) (43)
- Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study. (2016) (43)
- Porcine major histocompatibility complex (MHC) class I molecules and analysis of their peptide-binding specificities (2011) (43)
- Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study (2017) (43)
- Increased Insulin Receptor Binding to Monocytes from Insulu-dependent Diabetic Patients After a Low-Fat, High-Starch, High-Fiber Diet (1982) (42)
- Identification of two novel missense mutations in the human OB gene (1997) (42)
- Insulin resistance and maximal oxygen uptake (2003) (42)
- Mutation analysis of the MCHR1 gene in human obesity. (2005) (42)
- Huntington’s Disease Does Not Appear to Increase the Risk of Diabetes Mellitus (2009) (42)
- Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients. (2001) (42)
- AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I (2008) (41)
- Studies of insulin resistance in congenital generalized lipodystrophy * (1996) (41)
- Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis (2021) (41)
- Grey-box Modelling of Pharmacokinetic /Pharmacodynamic Systems (2004) (41)
- PGC-1α Gly482Ser Polymorphism Associates With Hypertension Among Danish Whites (2005) (41)
- Studies of associations between the Arg389Gly polymorphism of the β1‐adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects (2007) (40)
- The frequent UCP2 −866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes (2013) (40)
- Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes. (2009) (40)
- A statistical approach based on substitution of macronutrients provides additional information to models analyzing single dietary factors in relation to type 2 diabetes in danish adults: the Inter99 study. (2005) (40)
- Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1 (2008) (40)
- Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects. (2000) (40)
- Volume control in sickle cells is facilitated by the novel anion conductance inhibitor NS1652. (2000) (40)
- Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts (2020) (40)
- A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study (2011) (40)
- Genetic Risk Score of 46 Type 2 Diabetes Risk Variants Associates With Changes in Plasma Glucose and Estimates of Pancreatic β-Cell Function Over 5 Years of Follow-Up (2013) (40)
- Multiple insulin injections using a pen injector versus insulin pump treatment in young diabetic patients. (1987) (39)
- Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure (2010) (39)
- Comparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and Humans (2015) (39)
- Microbiome and metabolome features of the cardiometabolic disease spectrum (2022) (39)
- Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial (2009) (39)
- Targeting hyperglycaemia with either metformin or repaglinide in non‐obese patients with type 2 diabetes: results from a randomized crossover trial (2007) (39)
- An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men (1999) (39)
- Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release (2011) (38)
- A P 387 L Variant in Protein Tyrosine Phosphatase-1 B ( PTP-1 B ) Is Associated With Type 2 Diabetes and Impaired Serine Phosphorylation of PTP-1 B In Vitro (2001) (38)
- Sequence variants in the human cocaine and amphetamine-regulated transcript (CART) gene in subjects with early onset obesity. (1999) (38)
- Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes. (2005) (38)
- The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes. (2005) (38)
- Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3α and β isoforms in patients with NIDDM (1997) (37)
- White Coat Hypertension in NIDDM Patients With and Without Incipient and Overt Diabetic Nephropathy (1997) (37)
- Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
- Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (37)
- Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota (2017) (37)
- Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference. (2016) (37)
- Effect of physical training on glucose transporter protein and mRNA levels in rat adipocytes. (1993) (37)
- Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes. (2008) (36)
- TFAP2B Influences the Effect of Dietary Fat on Weight Loss under Energy Restriction (2012) (36)
- Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes. (2004) (36)
- Effects of perindopril on insulin sensitivity and plasma lipid profile in hypertensive non-insulin-dependent diabetic patients. (1992) (36)
- Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial (2016) (36)
- Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals (2011) (36)
- Influences of the Common FTO rs9939609 Variant on Inflammatory Markers Throughout a Broad Range of Body Mass Index (2011) (35)
- The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals (2008) (35)
- The Effects of Metformin on Adipocyte Insulin Action and Metabolic Control in Obese Subjects with Type 2 Diabetes (1989) (35)
- Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits (2009) (35)
- Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibers and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609. (2009) (35)
- Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity (2004) (35)
- Insulin Resistance and Insulin-Dependent Diabetes Mellitus (1987) (35)
- Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study (2015) (35)
- The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. (2008) (35)
- Predictors of future fasting and 2‐h post‐OGTT plasma glucose levels in middle‐aged men and women—the Inter99 study (2009) (34)
- Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies. (2018) (34)
- Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test (2010) (34)
- Insulin receptor binding and receptor-mediated insulin degradation in human adipocytes (1981) (34)
- Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus. (1997) (34)
- Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans (2018) (34)
- Identification of Four Amino Acid Substitutions in Hexokinase II and Studies of Relationships to NIDDM, Glucose Effectiveness, and Insulin Sensitivity (1995) (34)
- Insulin Receptors on Monocytes from Patients with Ketosis-prone Diabetes Mellitus (1978) (34)
- Influence of the PPAR-gamma2 Pro12Ala and ACE I/D polymorphisms on insulin sensitivity and training effects in healthy offspring of type 2 diabetic subjects. (2005) (34)
- Common Variation in LMNA Increases Susceptibility to Type 2 Diabetes and Associates With Elevated Fasting Glycemia and Estimates of Body Fat and Height in the General Population (2007) (34)
- Studies of genetic variability of the glucose transporter 2 promoter in patients with type 2 diabetes mellitus. (2001) (33)
- Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids. (2006) (33)
- Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population (2014) (33)
- Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents (2017) (33)
- Genetic determinants of serum vitamin B12 and their relation to body mass index (2016) (33)
- Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes (2013) (33)
- DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance (2016) (33)
- The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes (2008) (32)
- Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion (2004) (32)
- The Role of the Gut Microbiota in Childhood Obesity. (2016) (32)
- The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation (2012) (32)
- Letter: Partial trisomy 15 as a result of an unbalanced 12/15 translocation in a patient with a cloverleaf skull anomaly. (1976) (32)
- Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria (2019) (32)
- A role for coding functional variants in HNF4A in type 2 diabetes susceptibility (2010) (32)
- The Association of Alcohol and Alcohol Metabolizing Gene Variants with Diabetes and Coronary Heart Disease Risk Factors in a White Population (2010) (32)
- Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85α (2002) (32)
- Ocular surface microbiota in patients with aqueous tear-deficient dry eye. (2020) (32)
- Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle (2015) (31)
- Meta-analysis of exome array data identifies six novel genetic loci for lung function (2017) (31)
- The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals (2011) (31)
- Fat mass measured by DXA varies with scan velocity. (2002) (31)
- Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus (2001) (31)
- Impaired Insulin-Stimulated Nonoxidative Glucose Metabolism in Pancreas-Kidney Transplant Recipients: Dose-Response Effects of Insulin on Glucose Turnover (1996) (31)
- GLUT-4 content in plasma membrane of muscle from patients with non-insulin-dependent diabetes mellitus. (1993) (31)
- Pre- and posttranslational upregulation of muscle-specific glycogen synthase in athletes. (1994) (31)
- Study rationale and design of the CIMT trial: The Copenhagen Insulin and Metformin Therapy Trial (2009) (31)
- Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment (2019) (30)
- Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects (2006) (30)
- Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium (2017) (30)
- MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification (2014) (30)
- Affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota (2018) (30)
- Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity (2004) (30)
- Interactions of Lipid Genetic Risk Scores With Estimates of Metabolic Health in a Danish Population (2015) (30)
- High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus (2017) (30)
- Impaired Insulin Receptor Binding and Postbinding Defects of Adipocytes From Normal and Diabetic Pregnant Women (1986) (30)
- A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads (2009) (30)
- Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes? (2013) (30)
- Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B (2011) (30)
- Allelic Variants of Melanocortin 3 Receptor Gene (MC3R) and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets (2011) (29)
- Discovery of novel heart rate-associated loci using the Exome Chip (2017) (29)
- Reference values for serum total adiponectin in healthy non-obese children and adolescents. (2015) (29)
- No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels (2012) (29)
- Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis (2019) (29)
- The effect of GWAS identified BMI loci on changes in body weight among middle‐aged danes during a five‐year period (2014) (29)
- Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes (2020) (29)
- Past and current body size affect validity of reported energy intake among middle-aged Danish men. (2009) (28)
- Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people. (2008) (28)
- Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia (2017) (28)
- Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects. (2003) (28)
- Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity. (2005) (28)
- Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits. (2003) (28)
- Addendum: Enterotypes of the human gut microbiome (2014) (28)
- Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus. (1993) (28)
- Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits (2012) (28)
- The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample (2016) (28)
- The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes (2007) (28)
- The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: evidence from studies of 231 glucose-tolerant first degree relatives of type 2 diabetic probands. (1998) (27)
- NeuroD / BETA 2 Gene Variability and Diabetes No Associations to Late-Onset Type 2 Diabetes but an A 45 Allele May Represent a Susceptibility Marker for Type 1 Diabetes Among Danes (2000) (27)
- Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health (2021) (27)
- Numerous Brugada syndrome–associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality (2016) (27)
- The monocyte as a model for the study of insulin receptors in man (1977) (27)
- Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease (2022) (27)
- Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism (2001) (27)
- Diabetes mellitus caused by insulin-receptor blockade and impaired sensitivity to insulin. (1981) (27)
- Insulin receptors in the pregnant diabetic and her newborn. (1981) (27)
- Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity. (2005) (27)
- Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance (2006) (27)
- Influence of short-term dexfenfluramine therapy on glucose and lipid metabolism in obese non-diabetic patients. (1993) (27)
- The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy. (2008) (26)
- The effect of overweight and obesity on liver biochemical markers in children and adolescents. (2020) (26)
- Contraction-stimulated muscle glucose transport and GLUT-4 surface content are dependent on glycogen content. (1999) (26)
- In Vitro and In Vivo Studies of a Naturally Occurring Variant of the Human p85α Regulatory Subunit of the Phosphoinositide 3-Kinase Inhibition of Protein Kinase B and Relationships With Type 2 Diabetes, Insulin Secretion, Glucose Disappearance Constant, and Insulin Sensitivity (2001) (26)
- Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium (2019) (26)
- Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians (1996) (26)
- Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation. (1996) (26)
- Identification of peptides from foot-and-mouth disease virus structural proteins bound by class I swine leukocyte antigen (SLA) alleles, SLA-1*0401 and SLA-2*0401. (2013) (25)
- Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism (2022) (25)
- [Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno-2 study]. (1999) (25)
- Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes. (2010) (25)
- PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites. (2005) (25)
- Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 (2018) (25)
- Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes. (1996) (25)
- A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young. (1999) (25)
- Incretin and pancreatic hormone secretion in Caucasian non‐diabetic carriers of the TCF7L2 rs7903146 risk T allele (2013) (25)
- Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function* (2016) (25)
- Exophiala psychrophila sp. nov., a pathogenic species of the black yeasts isolated from farmed Atlantic salmon (1989) (25)
- Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2017) (25)
- Lens autofluorescence is increased in newly diagnosed patients with NIDDM (1996) (25)
- Mutations in HNF 1 A Result in Marked Alterations of Plasma Glycan Pro fi le (2013) (25)
- EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families. (2006) (24)
- The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status (2011) (24)
- Alterations in the hepatic insulin receptor kinase in genetic and acquired obesity in rats. (1989) (24)
- Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference. (2014) (24)
- Vejle Diabetes Biobank – a resource for studies of the etiologies of diabetes and its comorbidities (2016) (24)
- Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites. (2006) (24)
- Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy. (1995) (24)
- Insulin Receptor Assays Used in Human Studies: Merits and Limitations (1983) (24)
- The insulin receptor in normal and obese persons. (1976) (24)
- ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals (2018) (24)
- PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients. (2002) (24)
- A study of insulin receptors in human mononuclear leucocytes. (1976) (23)
- Circadian profiles of insulin receptors in insulin-dependent diabetics in usual and poor metabolic control. (1982) (23)
- Association of Birth Weight With Type 2 Diabetes and Glycemic Traits (2019) (23)
- Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria (2020) (23)
- Do Gene Variants Influencing Adult Adiposity Affect Birth Weight? A Population-Based Study of 24 Loci in 4,744 Danish Individuals (2010) (23)
- Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease (2013) (23)
- Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk (2017) (23)
- A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease (2015) (23)
- Low-grade inflammation independently associates with cardiometabolic risk in children with overweight/obesity. (2020) (23)
- The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men. (2005) (23)
- Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion (2015) (22)
- Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and identification of commonly occurring haplotypes using sequence specific low and high resolution primers. (2014) (22)
- Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts (2017) (22)
- Bioinformatics-Driven Identification and Examination of Candidate Genes for Non-Alcoholic Fatty Liver Disease (2011) (22)
- A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria (2018) (22)
- The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects (2003) (22)
- Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study (2022) (22)
- Functional SOCS1 polymorphisms are associated with variation in obesity in whites (2009) (22)
- A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. (2007) (22)
- Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity (2016) (22)
- Effects of hyperinsulinemia and hyperglycemia on insulin receptor function and glycogen synthase activation in skeletal muscle of normal man. (1991) (22)
- Iron-Overload-Related Disease in HFE Hereditary Hemochromatosis (2008) (22)
- Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits (2008) (22)
- Postbinding defects of insulin action in human adipocytes from uremic patients. (1985) (22)
- From the mixed economy to the negotiated economy: the Scandinavian countries (1990) (22)
- Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism (2020) (21)
- Impact of the peroxisome proliferator activated receptor-γ coactivator-1β (PGC-1β) Ala203Pro polymorphism on in vivo metabolism, PGC-1β expression and fibre type composition in human skeletal muscle (2007) (21)
- Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity. (2000) (21)
- Family and Population-Based Studies of Variation within the Ghrelin Receptor Locus in Relation to Measures of Obesity (2010) (21)
- Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor. (2016) (21)
- Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes. (2015) (21)
- Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders (2016) (21)
- Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsets (2014) (21)
- Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies (2012) (21)
- Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants (2012) (21)
- 1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents (2015) (21)
- Characterization of the insulin resistance of glucose utilization in adipocytes from patients with hyper- and hypothyroidism. (1988) (21)
- Activity of insulin receptor kinase and glycogen synthase in skeletal muscle from patients with chronic renal failure. (1989) (20)
- Two Randomized Cross-Over Trials Assessing the Impact of Dietary Gluten or Wholegrain on the Gut Microbiome and Host Metabolic Health (2014) (20)
- Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
- Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity (2018) (20)
- Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
- ‘Omics’‐driven discoveries in prevention and treatment of type 2 diabetes (2012) (20)
- Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark (2021) (20)
- Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India (2021) (20)
- Lewis phenotypes and the insulin resistance syndrome in young healthy white men and women. (1995) (20)
- Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance (1998) (19)
- Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study (2009) (19)
- ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations (2019) (19)
- Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration (2019) (19)
- The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention (2018) (19)
- Prevalence of a Polymorphism of the Phosphatidylinositol 3-Kinase p85α Regulatory Subunit (Codon 326Met→ile) in Japanese NIDDM Patients (1997) (19)
- Reference values for serum leptin in healthy non-obese children and adolescents (2016) (19)
- A Bayesian Multilocus Association Method: Allowing for Higher-Order Interaction in Association Studies (2007) (19)
- Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs. (2017) (19)
- One-carbon metabolism markers are associated with cardiometabolic risk factors. (2018) (19)
- Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes. (2011) (19)
- Target intervention against multiple‐risk markers to reduce cardiovascular disease in patients with type 2 diabetes (2004) (19)
- Variance of the SGK1 Gene Is Associated with Insulin Secretion in Different European Populations: Results from the TUEF, EUGENE2, and METSIM Studies (2008) (18)
- Hepatocyte nuclear factor-6: associations between genetic variability and Type II diabetes and between genetic variability and estimates of insulin secretion (1999) (18)
- Insulin Action and Insulin Secretion in Identical Twins With MODY: Evidence for Defects in Both Insulin Action and Secretion (1988) (18)
- No Consistent Effect of ADRB2 Haplotypes on Obesity, Hypertension and Quantitative Traits of Body Fatness and Blood Pressure among 6,514 Adult Danes (2009) (18)
- The effect of acute hyperglycemia on the plasma C-peptide response to intravenous glucagon or to a mixed meal in insulin-dependent diabetes mellitus. (1991) (18)
- Microbiome and Metabolome Features of the Cardiometabolic Disease 2 Spectrum 3 4 (2022) (18)
- Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients. (1994) (18)
- Cost-Effectiveness of Intensified Versus Conventional Multifactorial Intervention in Type 2 Diabetes Results and projections from the Steno-2 study (2008) (18)
- Elevated levels of plasma von Willebrand factor and the risk of macro- and microvascular disease in type 2 diabetic patients with microalbuminuria. (2001) (18)
- Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes (2018) (18)
- Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1 (2011) (18)
- The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes (2015) (18)
- Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate. (2003) (18)
- Glucose metabolism in children and adolescents: Population‐based reference values and comparisons to children and adolescents enrolled in obesity treatment (2019) (18)
- Glucose transport and metabolism in adipocytes from newly diagnosed untreated insulin-dependent diabetics. Severely impaired basal and postinsulin binding activities. (1985) (18)
- Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects (1978) (18)
- Variability of the Insulin Receptor Substrate-1, Hepatocyte Nuclear Factor-1α (HNF-1α), HNF-4α, and HNF-6 Genes and Size at Birth in a Population-Based Sample of Young Danish Subjects1 (2000) (18)
- Gestational diabetes and the human salivary microbiota: a longitudinal study during pregnancy and postpartum (2020) (18)
- Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval (2018) (18)
- The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats (2019) (17)
- Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population (2016) (17)
- A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents (2017) (17)
- Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes (2015) (17)
- The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients. (1998) (17)
- Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios (2018) (17)
- Multi-targeted and aggressive treatment of patients with type 2 diabetes at high risk: what are we waiting for? (2005) (17)
- IRS1, KCNJ11, PPARγ2 and HNF‐1α: do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes? (2006) (17)
- The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge (2011) (17)
- Discovery of a Met300Val variant in Shc and studies of its relationship to birth weight and length, impaired insulin secretion, insulin resistance, and type 2 diabetes mellitus. (1999) (17)
- The uncoupling protein 3 -55 C -->T variant is not associated with Type II diabetes mellitus in Danish subjects. (2001) (17)
- Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test (2010) (17)
- Alternative Splicing of Exon 17 and a Missense Mutation in Exon 20 of the Insulin Receptor Gene in Two Brothers with a Novel Syndrome of Insulin Resistance (Congenital Fiber-Type Disproportion Myopathy) (1999) (17)
- Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes (2009) (17)
- Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents (2019) (17)
- Increase in clinically recorded type 2 diabetes after colectomy (2018) (16)
- Decreased hepatic glucagon responses in Type 1 (insulin-dependent) diabetes mellitus (1991) (16)
- Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial (2016) (16)
- Intermediate expansions of a GAA repeat in the frataxin gene are not associated with type 2 diabetes or altered glucose-induced beta-cell function in Danish Caucasians. (1999) (16)
- Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations (2018) (16)
- Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes (2018) (16)
- In vivo action of glibenclamide in obese subjects with mild type 2 (non-insulin dependent) diabetes. (1988) (16)
- The effect of glibenclamide on insulin receptors in normal man: comparative studies of insulin binding to monocytes and erythrocytes. (1983) (16)
- Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus (2001) (16)
- Insulin receptors on monocytes of young healthy persons correlated with glucose tolerance and insulin sensitivity (1978) (16)
- Heterogeneity of insulin receptors in patients with untreated insulin-dependent diabetes mellitus. (1982) (16)
- Acute Actions of Sulfonylurea Drugs During Long-Term Treatment of NIDDM (1990) (16)
- Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion (2005) (16)
- Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis. (2019) (16)
- Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population (2001) (16)
- MATURITY-ONSET DIABETES OF THE YOUNG WITH END-STAGE NEPHROPATHY: A NEW INDICATION FOR SIMULTANEOUS PANCREAS AND KIDNEY TRANSPLANTATION? (2004) (16)
- Reference values for leptin/adiponectin ratio in healthy children and adolescents. (2019) (16)
- Identification and Functional Characterization of G 6 PC 2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G 6 PC 2-ABCB 11 Locus (2015) (16)
- Studies of variability in the islet amyloid polypeptide gene in relation to Type 2 diabetes (2003) (15)
- Beta-adrenergic regulation of prostaglandin E2 receptors in human and rat adipocytes. (1985) (15)
- Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2011) (15)
- A diet-induced gut microbiota component and related plasma metabolites are associated with depressive-like behaviour in rats (2020) (15)
- Transport and metabolism of D-glucose in human adipocytes. Studies of the dependence on medium glucose and insulin concentrations. (1988) (15)
- The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial: the Inter99 study. (2011) (15)
- Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes. (2010) (15)
- The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance. (1997) (15)
- A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01 (2016) (15)
- Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts (2014) (15)
- Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation (1999) (15)
- Limitations in the use of insulin or C-peptide alone in the assessment of beta-cell function in pancreas transplant recipients. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation. (1994) (15)
- Plasma Alkylresorcinols Reflect Gluten Intake and Distinguish between Gluten-Rich and Gluten-Poor Diets in a Population at Risk of Metabolic Syndrome. (2016) (15)
- Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study. (1995) (15)
- Kinetics of insulin binding and kinase activity of the partially purified insulin receptor from human skeletal muscle. (1990) (15)
- Expression of glycogen synthase and phosphofructokinase in muscle from Type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment (2004) (15)
- Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status (2016) (15)
- Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes (2007) (15)
- Lessons from whole-exome sequencing in MODYX families. (2014) (15)
- Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor‐1α gene and the relationship to β‐cell function during an OGTT in glucose‐tolerant women with and without previous gestational diabetes mellitus (2004) (14)
- Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C. (2008) (14)
- Interaction between Genetic Predisposition to Adiposity and Dietary Protein in Relation to Subsequent Change in Body Weight and Waist Circumference (2014) (14)
- Chronic Mild Hyperglycemia in GCK-MODY Patients Does Not Increase Carotid Intima-Media Thickness (2013) (14)
- Beneficial impact of intensified multifactorial intervention on risk of stroke: outcome of 21 years of follow-up in the randomised Steno-2 Study (2019) (14)
- Genetics of common forms of glycaemia with pathological impact on vascular biology: are we on the right track? (2005) (14)
- Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention (2022) (14)
- Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology (2016) (14)
- Genetic association analysis of LARS2 with type 2 diabetes (2009) (14)
- Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM. (1997) (14)
- GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report (2020) (13)
- Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young. (2015) (13)
- Secretion of neurotensin from isolated perfused porcine ileum (1988) (13)
- A Novel −192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-Onset Diabetes (2006) (13)
- Effects of sulfonylureas on adipocyte and skeletal muscle insulin action in patients with non-insulin-dependent diabetes mellitus. (1991) (13)
- Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults. (2009) (13)
- The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load (2011) (13)
- High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients (2014) (13)
- Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies. (2019) (13)
- Genome-wide association studies of human adiposity: Zooming in on synapses (2015) (13)
- Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria (2021) (13)
- Alpha 2-adrenergic binding and action in human adipocytes. Comparison between binding to plasma membrane preparations and to intact adipocytes. (1985) (13)
- Genetic Determinants of Weight Loss After Bariatric Surgery (2019) (13)
- Sex‐specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility (2014) (13)
- Comparison of Accuracy of Diabetes Risk Score and Components of the Metabolic Syndrome in Assessing Risk of Incident Type 2 Diabetes in Inter99 Cohort (2011) (13)
- Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes (2015) (13)
- Hurler/Scheie Phenotype (1978) (12)
- The Trp64Arg amino acid polymorphism of the beta3-adrenergic receptor gene does not contribute to the genetic susceptibility of diabetic microvascular complications in Caucasian type 1 diabetic patients. (1999) (12)
- Genetics of human gut microbiome composition (2020) (12)
- Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test (2011) (12)
- LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation. (2010) (12)
- Preserved insulin response to tolbutamide in hepatocyte nuclear factor‐1α mutation carriers (2005) (12)
- The importance of adrenaline, insulin and insulin sensitivity as determinants for blood pressure in young Danes (1995) (12)
- Gliclazide and insulin action in human muscle. (1991) (12)
- Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population (2018) (12)
- Gut microbiota in patients with type 2 diabetes mellitus (2015) (12)
- Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated g (1999) (12)
- Familial mild hyperglycemia associated with a novel ABCC8‐V84I mutation within three generations (2011) (12)
- Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses (2018) (12)
- Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples (2013) (12)
- Predicting glycated hemoglobin levels in the non-diabetic general population: Development and validation of the DIRECT-DETECT prediction model - a DIRECT study (2017) (12)
- Six novel mutations in the GCK gene in MODY patients (2006) (12)
- Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria: A post‐hoc analysis of the Steno‐2 trial (2018) (11)
- A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes: a post hoc analysis of the Steno-2 study (2018) (11)
- Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study (2020) (11)
- Insulin binding, insulin degradation and glucose metabolism in human monocytes (1979) (11)
- Impact of size at birth and prematurity on adult anthropometry in 4744 middle-aged Danes – The Inter99 study (2010) (11)
- A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production. (2016) (11)
- Fasting Plasma GLP-1 Is Associated With Overweight/Obesity and Cardiometabolic Risk Factors in Children and Adolescents (2021) (11)
- Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits (2005) (11)
- In vitro and in vivo studies of a naturally occurring variant of the human p85alpha regulatory subunit of the phosphoinositide 3-kinase: inhibition of protein kinase B and relationships with type 2 diabetes, insulin secretion, glucose disappearance constant, and insulin sensitivity. (2001) (11)
- No influence of sugar, snacks and fast food intake on the degree of obesity or treatment effect in childhood obesity (2016) (11)
- Sulfonylureas improve insulin binding and insulin action in non-insulin-dependent diabetes mellitus. (1984) (11)
- A −243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population‐based sample of 5857 middle‐aged White subjects (2007) (11)
- Tissue-Specific Regulation of Glucose Transporters in Different Forms of Obesity (1992) (11)
- An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese (2018) (11)
- Decreased insulin binding to erythrocytes in subjects with Klinefelter's syndrome. (1981) (10)
- Sister chromatid exchanges in cultured peripheral lymphocytes from twins (2004) (10)
- Associations between APOE Variants and Metabolic Traits and the Impact of Psychological Stress (2011) (10)
- Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes (2020) (10)
- Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case–control study (2015) (10)
- Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects. (2017) (10)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
- Hexose transport in human adipocytes: Factors influencing the response to insulin and kinetics of methylglucose and glucose transport (1981) (10)
- Association of alcohol consumption with allergic disease and asthma: a multi‐centre Mendelian randomization analysis* (2018) (10)
- Ponderal index at birth associates with later risk of gestational diabetes mellitus (2017) (10)
- The Effect of Chronic Hyperglycaemia on the Islet B‐cell Responsiveness in Newly Diagnosed Type 2 Diabetes (1992) (10)
- Reference values for fasting serum resistin in healthy children and adolescents. (2017) (9)
- Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone (2016) (9)
- The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment (2018) (9)
- A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects. (2004) (9)
- Erratum to: ‘Intake of Macro- and Micronutrients in Danish Vegans’ (2015) (9)
- The g/a Nucleotide Variant at Position −30 in the β-Cell-Specific Glucokinase Gene Promoter Has No Impact on the β-Cell Function in Danish Caucasians (1998) (9)
- Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (9)
- Variation in CHI3LI in Relation to Type 2 Diabetes and Related Quantitative Traits (2009) (9)
- Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus. (2004) (9)
- Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study (2021) (9)
- Studies of the variability of the hepatocyte nuclear factor‐1β (HNF‐1β / TCF2) and the dimerization cofactor of HNF‐1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and β‐cell function (2001) (9)
- Patients with psoriasis have a dysbiotic taxonomic and functional gut microbiota * (2022) (9)
- The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project: rationale and planned nationwide studies of genetic predictors, physical exercise, and individualized pharmacological treatment (2012) (9)
- Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes (2015) (9)
- Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation (2019) (9)
- Adipocyte Insulin Binding and Action in Moderately Obese NIDDM Patients After Dietary Control of Plasma Glucose: Reversal of Postbinding Abnormalities (1987) (9)
- Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
- The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals (2012) (9)
- Effects of prostaglandin E2, indomethacin and adenosine deaminase on basal and insulin-stimulated glucose metabolism in human adipocytes. (1985) (9)
- A Combined Analysis of 48 Type 2 Diabetes Genetic Risk Variants Shows No Discriminative Value to Predict Time to First Prescription of a Glucose Lowering Drug in Danish Patients with Screen Detected Type 2 Diabetes (2014) (9)
- Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography (2018) (9)
- Primordial Birdheaded Nanism Associated with Progressive Ataxia, Early Onset Insulin Resistant Diabetes, Goiter and Primary Gonadal Insufficiency (1989) (8)
- The Gut Microbiota in Type 2 Diabetes (2016) (8)
- Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
- The intestinal microbiome is a co-determinant of the postprandial plasma glucose response (2020) (8)
- ISPAD 2001: 1st Announcement (1999) (8)
- Expanding specificity of class I restricted CD8+ T cells for viral epitopes following multiple inoculations of swine with a human adenovirus vectored foot-and-mouth disease virus (FMDV) vaccine. (2016) (8)
- Defective Non‐insulin‐mediated and Insulin‐mediated Glucose Transport and Metabolism in Adipocytes from Obese and Lean Patients with Untreated Type 2 Diabetes Mellitus (1985) (8)
- Genome‐Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent (2018) (8)
- Lens Fluorescence in Relation to Glucose Tolerance and Genetic Predisposition to Type 2 Diabetes Mellitus in a Population-Based Study (2006) (8)
- Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight (2017) (8)
- The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study (2020) (8)
- Sagittal abdominal diameter and waist circumference appear to be equally good as identifiers of cardiometabolic risk. (2020) (8)
- Affective disorders impact prevalence of Flavonifractor and abundance of Christensenellaceae in gut microbiota (2021) (8)
- Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis (2018) (7)
- Application of urinary proteomics as possible risk predictor of renal and cardiovascular complications in patients with type 2-diabetes and microalbuminuria. (2018) (7)
- Large‐scale study of the −232C > G polymorphism of PCK1 in Type 2 diabetes (2006) (7)
- Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes (2019) (7)
- Insulin-resistant glucose metabolism in patients with microvascular angina--syndrome X. (1995) (7)
- Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis (2021) (7)
- The plasma C-peptide and insulin responses to stimulation with intravenous glucagon and a mixed meal in well-controlled Type 2 (non-insulin-dependent) diabetes mellitus: dependency on acutely established hyperglycaemia (1989) (7)
- Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673–686 (2015) (7)
- Variability of the insulin receptor substrate-1, hepatocyte nuclear factor-1alpha (HNF-1alpha), HNF-4alpha, and HNF-6 genes and size at birth in a population-based sample of young Danish subjects. (2000) (7)
- Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data (2015) (7)
- Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle. (2007) (7)
- Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children (2018) (7)
- Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity (2018) (7)
- Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies (2017) (7)
- FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses (2020) (7)
- Data integration for prediction of weight loss in randomized controlled dietary trials (2020) (7)
- Role of insulin receptors in insulin resistance. (1980) (7)
- Habitual physical activity is associated with lower fasting and greater glucose-induced GLP-1 response in men (2019) (6)
- Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining (2019) (6)
- The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes (2017) (6)
- Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries (2018) (6)
- Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum (2018) (6)
- Gut microbiota in human metabolic health and disease (2020) (6)
- Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations (2020) (6)
- Physiology of the Aging Vasculature The Gly 482 Ser genotype at the PPARGC 1 A gene and elevated blood pressure : a meta-analysis involving 13 , 949 individuals (2008) (6)
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
- Evidence of an Association Between the Arg 72 Allele of the Peptide YY and Increased Risk of Type 2 Diabetes (2005) (6)
- Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction (2022) (6)
- Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes (2011) (6)
- Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes (2012) (6)
- Long‐term effects of leisure time physical activity on risk of insulin resistance and impaired glucose tolerance, allowing for body weight history, in Danish men (2007) (6)
- Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control (1995) (6)
- Glucagon-receptor-antagonism-mediated β-cell regeneration as an effective anti-diabetic therapy. (2022) (6)
- Reduced binding and antilipolytic effect of prostaglandin E2 in adipocytes from patients with hyperthyroidism. (1986) (6)
- Treatment with NS 3623 , a novel Cl-conductance blocker , ameliorates erythrocyte dehydration in transgenic SAD mice : a possible new therapeutic approach for sickle cell disease (2001) (6)
- The Hurler/Scheie phenotype in children from a consanguineous marriage: case report with electronmicroscopy of the conjunctiva and ERG. (1980) (6)
- Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study (2020) (6)
- The HADHSC Gene Encoding Short-Chain l-3-Hydroxyacyl-CoA Dehydrogenase (SCHAD) and Type 2 Diabetes Susceptibility (2006) (6)
- Effects of glipizide on glucose metabolism and muscle content of the insulin-regulatable glucose transporter (GLUT 4) and glycogen synthase activity during hyperglycaemia in type 2 diabetic patients (1994) (5)
- Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial (2020) (5)
- Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents (2019) (5)
- Correlates of deteriorating vibration sensitivity 3 years from diagnosis of maturity onset diabetes (1981) (5)
- [Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics]. (2002) (5)
- Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures (2019) (5)
- Role of fasting duration and weekday in incretin and glucose regulation (2020) (5)
- Blood Pressure Levels in Male Carriers of Arg82Cys in CD300LG (2014) (5)
- Comparative studies of insulin binding to receptor from adipocytes, hepatocytes, monocytes and erythrocytes from the pig. Similarities with insulin receptor binding in man. (1988) (5)
- Intensified multifactorial treatment of patients with Type 2 diabetes: What can be achieved and does it pay off? (2009) (5)
- Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers (2021) (5)
- Obesity-associated fecal microbiota from human modulates body mass and metabolites in mice (2015) (5)
- Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies (2016) (5)
- The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders (2020) (5)
- Type 2-diabetes. Medicinsk teknologivurdering af screening, diagnostik og behandling (2003) (4)
- A Mutation Map for Human Glycoside Hydrolase Genes. (2020) (4)
- Monocyte-mediated antibody-dependent cytotoxicity. Modulation by Glycolysis and insulin. (2009) (4)
- EFFECTS OF EXERCISE ON INSULIN RECEPTORS ON ERYTHROCYTES AND MONOCYTES FROM INSULIN DEPENDENT DIABETICS (1980) (4)
- Correction: Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes? (2013) (4)
- Studies of the impact of a liver glucokinase promoter variant on glucose tolerance and insulin sensitivity index. (1997) (4)
- Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. (2022) (4)
- Increased insulin binding is not involved in the improved insulin effectiveness of gestational diabetics after hypoenergetic dieting. (1985) (4)
- GLP 1/2, Enteroglucagon, Glicentin, and Oxyntomodulin (2013) (4)
- Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years[S] (2016) (4)
- Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes (2019) (4)
- Protein Intake, Metabolic Status and the Gut Microbiota in Different Ethnicities: Results from Two Independent Cohorts (2021) (4)
- A De Novo Whole GCK Gene Deletion Not Detected by Gene Sequencing, in a Boy with Phenotypic GCK Insufficiency (2011) (4)
- Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology (2020) (4)
- Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors (2016) (4)
- The Role of the Gut Microbiome in Obesity (2014) (4)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
- Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study (2020) (4)
- Targeting Body Weight Regulation with Probiotics: A Review of Randomized Trials in Obese and Overweight People Free of Comorbidities (2015) (4)
- Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2018) (4)
- Glucagon Receptor Antagonism-Mediated β-Cell Regeneration as an Effective Anti-Diabetic Therapy (2021) (4)
- Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity (2020) (3)
- The influence of parental history of diabetes and offspring birthweight on offspring glucose metabolism in adulthood (2011) (3)
- Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population (2018) (3)
- The Effect of Intensive Insulin Therapy on the Insulin‐regulatable Glucose Transporter (GLUT4) Expression in Skeletal Muscle in Type 1 Diabetes (1993) (3)
- Syddansk Universitet Association analysis of 29 , 956 individuals confirms that a low-frequency variant at CCND 2 halves the risk of type 2 diabetes by enhancing insulin secretion (2015) (3)
- Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study. (2021) (3)
- Impact of rs361072 in the Phosphoinositide 3-Kinase p110β Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle (2010) (3)
- Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants (2019) (3)
- The gut microbiota in multiple sclerosis varies with disease activity (2023) (3)
- Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts. (2021) (3)
- The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians. (1998) (3)
- Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites. (2007) (3)
- Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result (2008) (3)
- A genetic variant in HK 1 is associated with pro-anemic state and HbA 1 c but not other glycemic control related traits Running head : HK 1 variant , glycated hemoglobin and anemia (2009) (3)
- Evidence of an association between genetic variation of the coactivator PGC-1 b and obesity (2005) (3)
- Erratum: Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia (2009) (3)
- Increased B and T Cell Responses in M. bovis Bacille Calmette-Guérin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis Antigen (2015) (3)
- Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium (2018) (3)
- Novel variants in the putative peroxisome proliferator-activated receptor {gamma} promoter and relationships with obesity in men. (2005) (3)
- Hurler/Scheie phenotype. Report of an inbred sibship with tapeto-retinal degeneration and electron-microscopie examination of the conjuctiva. (1978) (3)
- Prenatal diagnosis of the Hurler syndrome. (1979) (3)
- TCF 7 L 2 rs 7903146 – macronutrient interaction in obese individuals ’ responses to a 10-wk randomized hypoenergetic diet 1 – 3 (2010) (3)
- 1H‐MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity (2016) (3)
- Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest (2018) (3)
- Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes (2018) (3)
- The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine (2012) (3)
- Polygenic predisposition to breast cancer and the risk of coronary artery disease. (2019) (2)
- Validation of the Diabetes Risk Score, a Multi-Marker Panel that Assesses the Risk of Type 2 Diabetes: Combined Results of the Inter99 and Botnia Studies (2009) (2)
- ANALOGS OF THE HISTAMINE LIBERATING DIHYDROXYSESQUITERPENE LACTONE THAPSIGARGIN. SYNTHESIS, X‐RAY ANALYSIS AND CHEMISTRY (1985) (2)
- 21th European Congress on Obesity (ECO2014), Sofia, Bulgaria, May 28-31, 2014: Abstracts (2014) (2)
- Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis (2022) (2)
- Correction: The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation (2012) (2)
- 22nd European Congress on Obesity (ECO2015), Prague, Czech Republic, May 6-9, 2015: Abstracts (2015) (2)
- Hyperglucagonemia in Pediatric Adiposity Associates With Cardiometabolic Risk Factors but Not Hyperglycemia (2022) (2)
- Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations (2019) (2)
- Past and Current Body Size Affect Validity of Reported Energy Intake among (2009) (2)
- University of Groningen Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk (2011) (2)
- Genetic markers of abdominal obesity and weight loss after gastric bypass surgery (2021) (2)
- Interethnic analyses of blood pressure loci in populations of East Asian and European descent (2018) (2)
- A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults (2018) (2)
- Stool energy density is positively correlated to intestinal transit time and related to microbial enterotypes (2022) (2)
- List of authors from the Mendelian Randomization of Dairy Consumption Working Group (2018) (2)
- Continuous subcutaneous insulin infusion fails to correct impaired basal glucose metabolism and impaired insulin sensitivity of adipocytes from patients with type 1 (insulin-dependent) diabetes. (1986) (2)
- Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India (2021) (2)
- Multifactorial Intervention in Type 2 Diabetes (2007) (2)
- Correction: Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets (2006) (2)
- Genetic risk scores link body fat distribution with specific cardiometabolic profiles (2016) (2)
- In Vivo and Ex Vivo Inflammatory Markers of Common Metabolic Phenotypes in Humans. (2018) (2)
- Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species (2021) (2)
- Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models (2023) (2)
- Insulin gene mutations resulting in a MODY phenotype: marked differences in clinical presentation, metabolic status and pathogenic effect through ER retention (2009) (2)
- Microbiome Determinants and Physiological Effects of the Benzoate-Hippurate Microbial-Host Co-Metabolic Pathway (2019) (2)
- DECREASED INSULIN BINDING TO ERYTHROCYTES IN SUBJECTS WITH TURNER'S SYNDROME (1983) (2)
- Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes (2018) (2)
- and the Role of Rare Coding Variants in Type 2 Diabetes (2013) (2)
- Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes (2013) (2)
- Analysis of Swine Leukocyte Antigen Peptide Binding Profiles and the Identification of T cell Epitopes by Tetramer Staining (2012) (2)
- Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes. (2021) (2)
- Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test (2021) (2)
- Voices: Insulin and beyond. (2021) (1)
- 14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes. (2022) (1)
- [Gut microbiota may have influence on glucose and lipid metabolism]. (2013) (1)
- Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
- Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome. (2017) (1)
- Tu-W19:4 Impact of metformin versus repaglinide on glycemic regulation and non-glycemic cardiovascular risk-markers in non-obese patients with type-2 diabetes (2006) (1)
- Physical activity and sedentary behavior; mechanistic insights and role in disease prevention (2021) (1)
- A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links (2018) (1)
- A Mixed Meal Potentiates the Insulin Sensitivity of Glucose Transport and Metabolism in Adipocytes from Patients with Type 2 Diabetes Mellitus (1988) (1)
- Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide with implications for heart and kidney disorders. (2022) (1)
- A Cost Analysis of Intensified vs. Conventional Multifactorial Therapy of Patients with Type 2 Diabetes—The Steno 2 Study (2018) (1)
- Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 (2018) (1)
- Correction: Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants (2013) (1)
- EHMTI-0380. The association of migraine susceptibility loci with severe migraine characteristics in a clinic-based migraine sample (2014) (1)
- Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota (2016) (1)
- Gestational diabetes is associated with an aberrant gut microbiota during pregnancy and postpartum (2018) (1)
- Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes (2019) (1)
- Large scale trans-ethnic meta-analyses identify novel rare and common variants associated with blood pressure and hypertension (2016) (1)
- Multifactorial Intervention in Type 2 Diabetes mellitus (2000) (1)
- Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function. (2001) (1)
- [The genome and diabetes]. (2014) (1)
- Observation The uncoupling protein 3 –55 C →T variant is not associated with Type II diabetes mellitus in Danish subjects (2001) (1)
- Authors' reply to Sert's comment on low-grade inflammation independently associates with cardiometabolic risk in children with overweight/obesity. (2020) (1)
- A comprehensive reanalysis of publicly available GWAS datasets reveals an X chromosome rare regulatory variant associated with high risk for type 2 diabetes (2017) (1)
- IMPACT OF TRANSCRIPTION-FACTOR 7-LIKE (TCF7L2) GENE-VARIANTS ON THE RESPONSE TO ANTI-HYPERGLYCAEMIC TREATMENT IN NON-OBESE PATIENTS WITH TYPE-2 DIABETES (T2DM) (2008) (1)
- Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion (2017) (1)
- Selection on the FADS region in Europeans (2016) (1)
- Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
- Intensiveret multifaktoriel intervention hos patienter med type 2-diabetes mellitus og mikroalbuminuri: Steno-2-studietthe Steno-2 study (1999) (1)
- Recovery of gut microbiota of healthy adults following antibiotic exposure (2018) (1)
- Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report (2019) (1)
- A possible association between a dysfunctional skin barrier ( fi laggrin null-mutation status ) and diabetes : a cross-sectional study (1)
- FGL1 as a modulator of plasma D‐dimer levels: Exome‐wide marker analysis of plasma tPA, PAI‐1, and D‐dimer (2021) (1)
- A reference map of potential determinants for the human serum metabolome (2020) (1)
- Years of Life Gained by Multifactorial Intervention in Patients with Type 2 Diabetes and Microalbuminuria - 21 Years Follow-Up on the Steno-2 Study (2016) (1)
- Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine: a cross-sectional study. (2017) (1)
- The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism (2022) (1)
- Prospective Studies Exploring the Possible Impact of an ID3 Polymorphism on Changes in Obesity Measures (2018) (1)
- Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition (2019) (1)
- Disentangling disease- and drug signatures of the human gut microbiome: the case of type 2 diabetes mellitus (2016) (1)
- Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and the identification of commonly expressed haplotypes using sequence specific low- and high resolution primers (2012) (1)
- Exome-chip meta-analysis identifies novel loci, including ADAMTS6 associated with cardiac conduction (2018) (1)
- GLUT4 translocation in human muscle strips. (1997) (1)
- The diabetes risk score outperforms fasting plasma glucose and glucose tolerance tests: combined results from the Inter99 and Botnia Studies (2009) (1)
- Comparision of Compositional Differences and Relative Potency Between Different Manufacturers of Ragweed Pollen Extracts (2007) (1)
- O-24: A common amino acid polymorphism in IRS-1 causes impaired insulin signaling: Evidence from transfection studies (2009) (1)
- Increased frequency of rare missense PPP 1 R 3 B variants among Danish patients with type 2 (2019) (1)
- The role of one carbon metabolism and methylation capacity in metabolic syndrome (2015) (1)
- Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study (2020) (1)
- [Gut microbiota may influence childhood and adolescent onset obesity]. (2015) (1)
- Obesity: Beige adipocytes—will they beat obesity? (2015) (1)
- MR-proANP Associated with Body Mass Index in Patients with Anorexia Nervosa. (2019) (1)
- The effect of blood donation of women on the birthweight of their offspring (2018) (1)
- Slimming down via the microbiota (2013) (1)
- Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes (2022) (1)
- Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model (2014) (1)
- European Obesity Summit (EOS) – Joint Congress of EASO and IFSO-EC, Gothenburg, Sweden, June 1 – 4, 2016: Abstracts (2016) (1)
- Multiomics signatures of type 1 diabetes with and without albuminuria (2022) (1)
- Erratum: Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes (The American Journal of Human Genetics (2013) 93 (1072-1086)) (2014) (1)
- The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice (2023) (1)
- Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation (2011) (1)
- Evidence that the LARS2 gene represents a novel type 2 diabetes mellitus gene (2006) (1)
- Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota (2022) (1)
- Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study (2018) (1)
- Data from the Steno-2 multifactorial intervention study in type 2 diabetes supports the 'polypill' strategy to reduce cardiovascular risk (2004) (0)
- Arylsulphatase B studies in skin fibroblasts from patients with Maroteaux-Lamy syndrome with special reference to electrophoretic mobility and prenatal diagnosis (1980) (0)
- Abstract 14369: Long-term Reduction in Coronary Artery Disease and Stroke With 7,8 Years of Intensified, Multifactorial Intervention in Patients With Type 2 Diabetes and Microalbuminuria in the Steno-2 Study (2016) (0)
- No association between 24-h metabolic measures and 14 years weight gain (2006) (0)
- Integrative data analysis of genotype, microbiome and metabolomics for prediction of response to diet for improved metabolic health (2018) (0)
- Is somatostatin pivotal in intra-islet communication? — A knock down study (2012) (0)
- High Plasma Levels of Soluble Lectin‐like Oxidized Low‐Density Lipoprotein Receptor‐1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity (2023) (0)
- Is insulin secretion regulated by glucagon? (2012) (0)
- Syddansk Universitet High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus (2017) (0)
- Author response: Increase in clinically recorded type 2 diabetes after colectomy (2018) (0)
- Prevalence, associated factors and detrimental links to restless legs syndrome in danish blood donors (2017) (0)
- Enterotypes of thehumangutmicrobiome (2011) (0)
- Common amino acid substitution in IRS-4 are not associated with random NIDDM or insulin resistance (1998) (0)
- Positive and negative effects of blood donation (2017) (0)
- The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes (2020) (0)
- 246-OR: A Loss-of-Function Mutation in the Sucrase-Isomaltase Gene Is Linked to a Markedly Healthier Metabolic Profile in Greenlanders (2020) (0)
- The effect of gluten on the urine metabolome of non-celiac adults assessed by GC-MS (2014) (0)
- Several gene polymorphisms but not FTO variant modulate resting energy expenditure and fat-induced thermogenesis in obese subjects: The NUGENOB Study (2008) (0)
- University of Dundee Processes Underlying Glycemic Deterioration in Type 2 Diabetes IMI DIRECT Consortium; Bizzotto, Roberto; Jennison, Christopher; Jones, Angus G.; Kurbasic, (2020) (0)
- Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark (2021) (0)
- Genome-Wide Association Meta-Analysis Using a Recessive Model Illuminates Genetic Architecture of Type 2 Diabetes (2021) (0)
- The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention (2018) (0)
- Rosiglitazone monotherapy for type 2 diabetes mellitus—too soon to ADOPT? (2007) (0)
- An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents (2022) (0)
- 54 EFFECT OF ONE YEAR TREATMENT WITH INSULIN AND ORAL GLUCOSE-LOWERING AGENTS ON LIPID LEVELS IN NON-OBESE PATIENTS WITH TYPE 2-DIABETES (2011) (0)
- Enterotypes of the human gut microbiome (Addendum) (2014) (0)
- Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment. (2023) (0)
- Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes (2018) (0)
- The Impact of Socioeconomic factors on donation Frequency (2016) (0)
- Hepatocyte nuclear factor-6: Studies of associations between genetic variability and type 2 diabetes or estimates of insulin secretion (1999) (0)
- Fasting and oral glucose-stimulated levels of GIP and GLP-1 are highly familial traits (2012) (0)
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (2018) (0)
- O-4: Cloning and mutational analysis of the ob gene in juvenile onset obesity (2009) (0)
- Associations of genetic determinants of vitamin B12 and folate status with hay fever and asthma: a Mendelian randomization (2017) (0)
- The gut microbiome in cardio-metabolic health (2015) (0)
- Plasma Alkylresorcinols Reflect Gluten Intake and Distinguish between Gluten-Rich and Gluten-Poor Diets in a Population at Risk of Metabolic Syndrome 1–3 (2016) (0)
- Syddansk Universitet Effect of Antibiotics on Gut Microbiota , Gut Hormones and Glucose Metabolism (2015) (0)
- PS7 - 3. Predicting Glycated Haemoglobin in the Non-Diabetic General Population: a DIRECT Study (2013) (0)
- The `polypill' to reduce cardiovascular risk: proof of concept Data from the Steno-2 multifactorial intervention study in type 2 diabetes supports the `polypill' strategy to reduce cardiovascular risk (2004) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
- O-49: A prevalent amino acid polymorphism at codon 325Met->IIe in the gene encoding the phosphatidylinositol 3-kinase p85α regulatory subunit is associated with decreased glucose tolerance and glucose effectiveness (2009) (0)
- The effect of gluten on the host-microbial metabolism assessed by urinary metabolomics (2015) (0)
- Genetic Analysis of Kru¨ppel-Like Zinc Finger 11 Variants in 5864 Danish Individuals: Potential Effect on Insulin Resistance and Modified Signal Transducer and Activator of Transcription-3 Binding by Promoter Variant (cid:1) 1659G > C (2008) (0)
- Microrna biomarkers for psoriasis arthritis - early results (2016) (0)
- University of Dundee Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes Koivula, (2014) (0)
- 237-OR: Beneficial Impact of Intensified Multifactorial Intervention on Stroke—The Steno-2 Study (2019) (0)
- The 'polypill' to reduce cardiovascular risk : proof of concept : healthcare management (2005) (0)
- P-108: Phenotype characteristics of two Danish MODY families with linkage to chromosome 12 (2009) (0)
- measured ectopic fat in liver and muscle in danish lean and obese children and adolescents (2015) (0)
- Studies of the bugs within: telling sickness from cure (2018) (0)
- Association of general health and lifestyle factors with the salivary microbiota – Lessons learned from the ADDITION-PRO cohort (2022) (0)
- Abstract 10916: Mendelian Randomization Studies Do Not Support a Causal Effect of Plasma Lipids on Insulin Sensitivity (2012) (0)
- The frequent UCP2-866G > A protects against insulin resistance in Danes: large-scale studies of obesity and related metabolic traits (2008) (0)
- Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity. (2023) (0)
- Genetic variation related to tolbutamide and GLP-1 stimulated insulin secretion converges functionally in protein network space: a DIRECT study (2014) (0)
- Author's response to reviews Title:Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study Authors: (2015) (0)
- Intensive therapy delayed microvascular complications in patients with type 2 diabetes mellitus and microalbuminuria (1999) (0)
- Plasma Alkylresorcinol Concentrations as a Novel Measure of Compliance to a Gluten‐Free Diet (2016) (0)
- Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality. (2023) (0)
- Mutation in the Human Insulin Receptor Gene A Novel Syndrome of Autosomal-Dominant Hyperinsulinemic Hypoglycemia Linked to a (2015) (0)
- Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525 (2015) (0)
- P-107: A common polymorphism in the insulin receptor gene is a marker of non-insulin dependent diabetes mellitus and reduced first-phase insulin secretion in a Danish population of Caucasians (2009) (0)
- Human leukocyte antigen class II association with infectious events among Danish blood donors (2016) (0)
- Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists (2023) (0)
- Author ' s response to reviews Title : Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle (2015) (0)
- Syddansk Universitet H-1-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents (2017) (0)
- Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria (2019) (0)
- PROactive study (2006) (0)
- Systems genetics design and analyses of obesity in Danish and Indian child cohorts and in pig model (2012) (0)
- Nature Genetics | Article (2015) (0)
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (0)
- P-110: Measurement of insulin receptor kinase activity in muscle and erythrocytes of a family with mutations of the insulin receptor gene (2009) (0)
- Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2019) (0)
- Rare sequence variants that disrupt ASGR 1 function lower non-HDL cholesterol and protect against coronary artery disease (2016) (0)
- Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test (2021) (0)
- Author response: Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining (2019) (0)
- (1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity (2018) (0)
- Genetic polymorphisms explain variation in the ability to regulate fat oxidation (2007) (0)
- Dietary determinants of one carbon metabolism and methylation capacity (2015) (0)
- Sagittal abdominal diameter and waist circumference are equally good as identifiers of cardiometabolic risk (2019) (0)
- Universitet High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus (2017) (0)
- The frequent UCP 2-866 G > A polymorphism protects against insulin resistance and is associated with obesity A study of obesity and related metabolic traits among 17 (2012) (0)
- Genetic studies of birth weight give biological insights into links with adult disease (2016) (0)
- Author Correction: Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models. (2023) (0)
- Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes (2022) (0)
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications (2023) (0)
- University of Southern Denmark High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus (2017) (0)
- [Diabetes in infants may be treated with sulfonylurea as a replacement for insulin]. (2009) (0)
- Role of fasting duration and weekday in incretin and glucose regulation (2021) (0)
- Associations between plasma incretin hormone release and aortic stiffness and blood pressure in individuals without known diabetes: The ADDITION-PRO study (2014) (0)
- [Molecular pathogenesis in monogenic and polygenic obesity]. (2006) (0)
- A network of pleiotropic genes for metabolic syndrome and inflammation (2013) (0)
- Trends in Excellent and Interdisciplinary Lifestyle, Obesity and Metabolic Research (2018) (0)
- Abstract: Abnormal glucose tolerance after gestational diabetes mellitus: A long-term follow up study of a Danish population (2002) (0)
- Meta-analyzed single SNP interactions with physical activity* on BMI. (2013) (0)
- Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study (2020) (0)
- No association of mutations in NeuroD/BETA2 with MODY in Danish and Italian Caucasians (2000) (0)
- Syddansk Universitet The type 2 diabetes risk allele of TMEM 154-rs 6813195 associates with decreased beta cell function in a study of 6 , 486 (2015) (0)
- The QT-interval prolonging variant p.D85N of KCNE1 associates with reduced levels of insulin after an oral glucose load (2014) (0)
- Use of Danish National Registers to identify parental history of type 2 diabetes for gene-environment interaction and association studies (2015) (0)
- [Insulin receptors. A new understanding of the physiopathological mechanisms in the development of insulin resistance in overweight persons]. (1981) (0)
- Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (0)
- Studies of Relationships to Type 2 Diabetes, Maturity-Onset Diabetes of the Young, and Gestational Diabetes Mellitus (2004) (0)
- [1,5 ppm fluoride in natural drinking water. Impressions of a journey to Vordingborg, Denmark] (2020) (0)
- Dietary glycemic index, glycemic load, fiber, simple sugars, and insulin resistance : The Inter99 study. Author's reply (2005) (0)
- Københavns Universitet ( 1 ) H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity (2016) (0)
- Intensiv multifaktoriel behandling og mortalitet ved type 2- diabetes - Sekundærpublikation (2008) (0)
- The Functional Thr130Ile and Val255Met Polymorphisms of the Hepatocyte Nuclear Factor-4 (cid:1) (HNF4A): Gene Associations with Type 2 Diabetes or Altered (cid:2) -Cell Function among Danes (2005) (0)
- How common is hidradentitis suppurativa (2016) (0)
- Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials (2016) (0)
- The role of gut microbiota in childhood obesity. A review of evidence and perspectives (2015) (0)
- [Insulin receptors and the effect of insulin. Possible pathogenetic significance of abnormalities of insulin receptors and post-receptor function in diabetes mellitus and other insulin-resistant conditions]. (1986) (0)
- Lack of association between polymorphic markers within 11b-hydroxysteroid dehydrogenase type 1 gene (HSD11B1) and obesity (2002) (0)
- Aalborg Universitet Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring (2019) (0)
- A common variant downstream of PCSK2 is associated with reduced tolbutamide stimulated insulin release: a DIRECT study (2014) (0)
- Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study (2020) (0)
- Mechanisms of action of metformin in patients with non insulin dependent diabetes mellitus niddm (1987) (0)
- Statin therapy is associated with lower prevalence of gut microbiota dysbiosis (2020) (0)
- No association of the Hph1 insulin gene polymorphism to type 2 diabetes or insulin secretion in Danish Caucasians (2000) (0)
- Authors' reply to Kahn's comment. (2021) (0)
- Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
- Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes (2018) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
- Genetic association analysis of 13 nuclear encoded mitochondrial candidate genes with type 2 diabetes: the DAMAGE study (2010) (0)
- Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios (2018) (0)
- Whole‐body Glucose Metabolism in Obese Patients with Type 2 Diabetes Mellitus: the Impact of Hypertension and Strict Blood Glucose Control (1995) (0)
- Mother–Child Microbiomes (2017) (0)
- Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study (2020) (0)
- P-115: Sequence variants in the sulfonylurea receptor gene are associated with non-insulin dependent diabetes mellitus and with decreased insulin secretion after an intravenous tolbutamide challenge (2009) (0)
- Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2018) (0)
- A genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic beta-cell function over five years of follow-up (2013) (0)
- DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance (2016) (0)
- Intake of macro- and micronutrients in (2015) (0)
- Track 1 – Track 5 (2008) (0)
- Impact of a vegan diet on the human salivary microbiota (2018) (0)
- Regulation and function of FTO expression Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue (2009) (0)
- Mendelian Randomization Studies of the Role of Biomarkers in Type 2 Diabetes (2009) (0)
- P-118: Insulin sensitivity and body weight changes in young Caurcasian carriers of the codon 64 amino acid polymorphism of the β3-adrenergic receptor gene (2009) (0)
- Characterisation of mechanisms responsible for uraemic insulin resistance: in vitro experiments. (1985) (0)
- Associations of physical activity intensity levels and cardiorespiratory fitness with glucose-induced GLP-1 responses (2017) (0)
- FTO genotype and weight loss (2018) (0)
- Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population (2018) (0)
- Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations (2021) (0)
- Interaction of Diet/Lifestyle Intervention and TCF7L2 Genotype on Glycemic Control and Adiposity among Overweight or Obese Adults: Big Data from Seven Randomized Controlled Trials Worldwide (2021) (0)
- Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
- 1 Talks 1 Quantifying The Bias In Disease Risk Estimates Associated With A Deleterious Mutation Using Families Ascertained Through One Affected Individual (2006) (0)
- Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism (2020) (0)
- 1H MRS measured ectopic fat in liver and muscle in Danish lean and obese children and youths (2015) (0)
- Colonic transit time relates to bacterial metabolism and mucosal turnover in the human gut (2016) (0)
- University of Southern Denmark Antibiotic regimens for neonatal sepsis A protocol for a systematic review with meta-analysis (2019) (0)
- A genome-wide association study of IVGTT-based measures of first phase insulin secretion refines the underlying physiology of type 2 diabetes variants Mechanisms of type 2 diabetes genetic risk factors (2017) (0)
- [Gut microbiota may influence childhood and adolescent onset obesity]. (2014) (0)
- Syddansk Universitet Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish / North-European White children and adolescents (2017) (0)
- Applying 8-oxoGuo for Prediction of Mortality in Patients with Type 2 Diabetes and Microalbuminuria—A Post-Hoc Analysis of the Steno-2 Trial (2018) (0)
- A combined prediction strategy increases identification of peptides bound with high affinity and stability to porcine MHC class I molecules SLA-1*04:01, SLA-2*04:01, and SLA-3*04:01 (2015) (0)
- Identification of swine influenza virus epitopes and analysis of multiple specificities expressed by cytotoxic T cell subsets (2014) (0)
- Aalborg Universitet Aberrant intestinal microbiota in individuals with prediabetes (2018) (0)
- CTL epitopes of FMDV determined by NetMHCpan-driven predictions of SLA/peptide binding, confirmed by tetramer complex formation and staining (2010) (0)
- PO22-724 IMPACT OF METFORMIN VERSUS REPAGLINIDE ON POSTPRANDIAL GLYCAEMIA AND PLASMA LIPOPROTEINS IN NON-OBESE PATIENTS WITH TYPE-2 DIABETES MELLITUS (T2DM) (2007) (0)
- 42nd EASD Annual Meeting of the European Association for the Study of Diabetes (2006) (0)
- Erratum to: Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release (2011) (0)
- Tracking the elusive cytotoxic T cell response in pigs (2016) (0)
- Determining peptide binding motifs for the SLA-2*0401 Class I MHC and identification of epitopes from foot-and-mouth disease virus (FMDV) P1 protein. (43.16) (2010) (0)
- From viral genome to specific peptide epitopes: methods for identifying porcine T cell epitopes based on in silico predictions, in vitro identification and ex vivo verification (P6098) (2013) (0)
- Analysis of the cytotoxic T lymphocyte response of MHC-defined swine to foot-and-mouth disease virus (170.14) (2011) (0)
- [Genetics in non-autoimmune diabetes. The Danish Society of Endocrinology]. (2008) (0)
- Ad5-vectored FMDV vaccine elicits antigen-specific CTL responses in swine. (43.10) (2010) (0)
- Analogues of the histamine liberating dihydroxysesquiterpene lactone thapsigargin. Synthesis, X-ray analysis and chemistry (1985) (0)
- ion channel openers (1993) (0)
- Substituted phenyl derivatives, their manufacture and use (1998) (0)
- Adapting lab scale synthesis to production-mature processes, illustrated by a large-scale industrial synthesis of [D-Ala1]-Peptide T-amide (1992) (0)
- Urea and amide derivatives and their use in the regulation of potassium channels in cell membranes (1995) (0)
- Acidic group-containing phenyl derivatives, their preparation and their use as chloride channel blockers (1997) (0)
- 679: A COMPUTATIONAL FRAMEWORK TO PREDICT LIVER AND INTRA-ABDOMINAL FAT THROUGH MICROBIOME, METABOLOME AND BIO-CLINICAL DATA INTEGRATION (2022) (0)
- Urea and amide derivatives and their use for the control of cell membrane permanent potassium-channels (1994) (0)
- Investigations towards the synthesis of vinblastine and vinblastine analogs (1992) (0)
- Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses (2018) (0)
- Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium (2017) (0)
- Letters to the Editor (1976) (0)
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