Ora Mendelsohn Rosen | Academic Influence

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Ora Mendelsohn Rosen

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#605

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Ora Mendelsohn Rosen's Degrees

Bachelors Biology University of California, Berkeley

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Why Is Ora Mendelsohn Rosen Influential?

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According to Wikipedia, Ora Mendelsohn Rosen was an American medical researcher who investigated the influence of hormones, particularly insulin, on the control of cell growth. She was a professor at the Albert Einstein College of Medicine and Memorial Sloan Kettering Cancer Center and a member of the National Academy of Sciences.

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Ora Mendelsohn Rosen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes (1985) (1886)
After insulin binds. (1987) (582)
Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. (1978) (545)
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. (1987) (474)
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. (1986) (456)
Protein phosphorylation. (1975) (425)
Phosphorylation activates the insulin receptor tyrosine protein kinase. (1983) (371)
Organelle relationships in cultured 3T3-L1 preadipocytes (1980) (312)
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate. (1985) (291)
Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. (1987) (270)
Growth factors rapidly induce expression of the glucose transporter gene. (1988) (238)
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid. (1988) (210)
Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes. (1972) (202)
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta. (1982) (194)
Glucose transporters serve as water channels. (1990) (191)
Reversible autophosphorylation of a cyclic 3':5'-AMP-dependent protein kinase from bovine cardiac muscle. (1975) (182)
Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle. (1974) (180)
Acquisition of increased hormone sensitivity during in vitro adipocyte development. (1977) (164)
Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle. (1972) (164)
Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A. (1991) (148)
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor. (1986) (142)
Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle. (1976) (136)
Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. (1986) (136)
Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta. (1984) (127)
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. (1987) (119)
Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein. (1988) (114)
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product. (1987) (112)
Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody. (1986) (111)
Resolution of the phosphorylated and dephosphorylated cAMP-binding proteins of bovine cardiac muscle by affinity labeling and two-dimensional electrophoresis. (1979) (107)
Purification and properties of the human placental insulin receptor. (1981) (106)
Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6. (1983) (101)
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation. (1986) (101)
Phosphorylation of exogenous substrates by the insulin receptor-associated protein kinase. (1983) (95)
Tunicamycin‐mediated depletion of insulin receptors in 3T3‐L1 adipocytes (1979) (95)
The role of cyclic AMP in the phosphorylation of proteins in human erythrocyte membranes. (1973) (94)
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. (1979) (92)
Structure and ligand specificity of the Drosophila melanogaster insulin receptor (1987) (90)
Mechanism of self-phosphorylation of adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle. (1976) (88)
Properties of an adenyl cyclase partially purified from frog erythrocytes. (1969) (87)
Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle. (1973) (87)
Effect of cAMP and ATP on the reassociation of phosphorylated and nonphosphorylated subunits of the cAMP-dependent protein kinase from bovine cardiac muscle. (1977) (85)
Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester. (1985) (84)
Purification of phosphoprotein phosphatase from bovine cardiac muscle that catalyzes dephosphorylation of cyclic AMP-binding protein component of protein kinase. (1977) (79)
Tissue localization of Drosophila melanogaster insulin receptor transcripts during development (1988) (78)
Dexamethasone regulates the beta-adrenergic receptor subtype expressed by 3T3 L1 preadipocytes and adipocytes. (1982) (76)
Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes. (1978) (75)
Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope. (1989) (73)
Description of a protein kinase derived from insulin-treated 3T3-L1 cells that catalyzes the phosphorylation of ribosomal protein S6 and casein. (1983) (72)
Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis. (1985) (71)
Interconversion of cyclic nucleotide-activated and cyclic nucleotide-independent forms of a protein kinase from beef heart. (1971) (71)
Synthesis, purification, and characterization of the cytoplasmic domain of the human insulin receptor using a baculovirus expression system. (1988) (69)
Purification and properties of a specific fructose 1,6-diphosphatase from Candida utilis. (1965) (68)
The role of insulin receptor autophosphorylation in signal transduction. (1991) (68)
Purification of a phosphoinositide-specific phospholipase C from bovine brain. (1987) (68)
Soluble cyclic AMP-dependent protein kinases: review of the enzyme isolated from bovine cardiac muscle. (1977) (68)
Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits (1989) (67)
Preparation and properties of a cyclic 3',5'-nucleotide phosphodiesterase isolated from frog erythrocytes. (1970) (67)
Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes. (1985) (66)
Modulation of Fc-mediated phagocytosis by cyclic AMP and insulin in a macrophage-like cell line. (1977) (62)
Cyclic AMP-dependent protein kinase from bovine heart muscle. (1974) (61)
Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes. (1983) (60)
The effect of catecholamines on the adenyl cyclase of frog and tadpole hemolysates. (1968) (59)
Drosophila cAMP-dependent protein kinase. (1984) (59)
Differentiation-dependent expression of catecholamine-stimulated adenylate cyclase. Roles of the beta-receptor and G/F protein in differentiating 3T3-L1 adipocytes. (1981) (59)
Self-phosphorylation of cyclic guanosine 3':5'-monophosphate-dependent protein kinase from bovine lung. Effect of cyclic adenosine 3':5'-monophosphate, cyclic guanosine 3':5'-monophosphate and histone. (1977) (55)
Recent studies of the 3T3-L1 adipocyte-like cell line. (1979) (55)
Structure and Function of Insulin Receptors (1989) (54)
The effect of nucleotides and a nondialyzable factor on the hydrolysis of cyclic AMP by a cyclic nucleotide phosphodiesterase from beef heart. (1971) (53)
Trifluoperazine inhibits phagocytosis in a macrophagelike cultured cell line (1981) (53)
Functional expression of mammalian glucose transporters in Xenopus laevis oocytes: evidence for cell-dependent insulin sensitivity (1989) (52)
Regulation of fatty acid synthetase concentration and activity during adipocyte differentiation. Studies on 3T3-L1 cells. (1980) (52)
Genetic analysis of the role of cAMP in mediating effects of interferon. (1982) (51)
A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells. (1986) (51)
Lipolytic stimulation modulates the subcellular distribution of hormone-sensitive lipase in 3T3-L1 cells. (1984) (51)
Radioimmunoassay of bovine heart protein kinase. (1976) (50)
An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity. (1985) (48)
Autophosphorylation of cGMP-dependent protein kinase. (1981) (48)
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. (1980) (48)
Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression. (1974) (47)
Purification of a bovine liver S6 kinase. (1987) (44)
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor. (1987) (44)
Purification and properties of a cyclic nucleotide phosphodiesterase from bovine heart. (1972) (44)
Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo. (1986) (43)
Another version of the human insulin receptor kinase domain: expression, purification, and characterization. (1989) (43)
Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. (1972) (42)
Identification and characterization of a latent pool of insulin receptors in 3T3-L1 adipocytes. (1982) (37)
Purification and properties of fructose 1,6-diphosphatase from Polysphondylium pallidum. (1966) (35)
THE MECHANISM OF ACTION OF ALDOLASES. VI. CRYSTALLIZATION OF DEOXYRIBOSE 5-PHOSPHATE ALDOLASE AND THE NUMBER OF ACTIVE SITES. (1965) (34)
Insulin stimulates the phosphorylation of ribosomal protein S6 in a cell-free system derived from 3T3-L1 adipocytes. (1981) (33)
Ultrastructural analysis of the organization and distribution of insulin receptors on the surface of 3T3‐L1 adipocytes: Rapid microaggregation and migration of occupied receptors (1985) (32)
Evidence that facilitative glucose transporters may fold as beta-barrels. (1993) (32)
Polylysine activates and alters the divalent cation requirements of the insulin receptor protein tyrosine kinase (1988) (32)
Cyclic adenosine 3':5'-monophosphate-mediated insulin secretion and ribosomal protein phosphorylation in a hamster islet cell tumor. (1977) (29)
Properties of protein kinase and adenylate cyclase‐deficient variants of a macrophage‐like cell line (1979) (28)
Hormonal regulation of the phosphorylation of ATP citrate lyase in 3T3-L1 adipocytes. Effects of insulin and isoproterenol. (1982) (28)
Interaction of cyclic GMP and cyclic AMP with a cyclic nucleotide phosphodiesterase of the frog erythrocyte. (1970) (28)
Phosphorylation of the insulin receptor by a casein kinase I-like enzyme. (1991) (27)
Hydrolysis of glycosyl-phosphatidylinositol in response to insulin is reduced in cells bearing kinase-deficient insulin receptors. (1990) (27)
Activity stain for the detection of cyclic nucleotide phosphodiesterase separated by polyacrylamide gel electrophoresis and its application to the cyclic nucleotide phosphodiesterase of beef heart. (1971) (27)
THE EFFECTS OF TRIFLUOPERAZINE ON THE MACROPHAGE‐LIKE CELL LINE, J774 * (1980) (27)
Mn2(+)-binding properties of a recombinant protein-tyrosine kinase derived from the human insulin receptor. (1990) (27)
The insulin receptor and tyrosine protein kinase activity. (1984) (26)
Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system. (1993) (26)
Functional expression of murine multidrug resistance in Xenopus laevis oocytes. (1990) (25)
Molecular structure and characterization of bovine heart protein kinase. (1975) (21)
Reconstitution of an insulin signaling pathway in Xenopus laevis oocytes: coexpression of a mammalian insulin receptor and three different mammalian hexose transporters (1990) (21)
Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes. (1973) (20)
Stimulation of polyphosphoinositide hydrolysis by thrombin in membranes from human fibroblasts. (1987) (20)
Antibodies to deduced sequences of the insulin receptor distinguish conserved and nonconserved regions in the IGF-I receptor. (1986) (20)
An assay for protein kinase activity on polyacrylamide gels (1974) (19)
The dissociation of D-fructose 1,6-diphosphatase by adenosine 5'-phosphate. (1967) (19)
The structure-activity relationships of adrenergic compounds that act on the adenyl cyclase of the frog erythrocyte. (1970) (19)
The development of hormone sensitivity by the adenyl cyclase of the tadpole erythrocyte. (1969) (19)
Inhibition of a cyclic nucleotide phosphodiesterase from beef heart by catecholamines and related compounds. (1972) (19)
Expression of inducible membrane-anchored insulin receptor kinase enhances deoxyglucose uptake. (1991) (18)
Structure, biosynthesis, and function of the hexose transporter in Chinese hamster ovary cells deficient in N‐acetylglucosaminyltransferase 1 activity (1988) (18)
A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs (1991) (18)
Reversible autophosphorylation of type II cAMP-dependent protein kinase: distinction between intramolecular and intermolecular reactions. (1983) (17)
Factors which influence cyclic AMP formation and degradation in an islet cell tumor of the Syrian hamster. (1971) (17)
Regulation of FDPase in C. utilis (1965) (16)
Biochemical analysis of mutants of a macrophage cell line resistant to the growth-inhibitory activity of interferon (1984) (15)
Chemical modification of the allosteric and catalytic sites of fructose 1,6-diphosphatase. (1966) (15)
The Acetaldehyde-2-Deoxy-D-ribose 5-Phosphate Aldolase Complex: Comparison of the Product Obtained on Borohydride Reduction and Hydrolysis with Synthetic N6-Ethyllysine (1964) (15)
Characterization of a protein acyl kinase from Caulobacter crescentus. (1972) (15)
A bacterial activator of frog erythrocyte adenyl cyclase. (1970) (14)
Insulin receptor in Drosophila melanogaster (1986) (13)
Purification and characterization of guanylate cyclase from Caulobacter crescentus. (1974) (12)
Insulin-dependent tyrosine protein kinase: cellular distribution and copurification with the insulin receptor. (1985) (12)
Properties of the cyclid AMP-dependent protein kinase from bovine and porcine heart. (1975) (11)
Structure-Activity Relationships of Adrenergic Compounds on the Adenylate Cyclase of Frog Erythrocytes (1974) (11)
Insulin-Receptor Approaches to Studying Protein Kinase Domain (1990) (10)
Characterization of cyclic 3', 5'-nucleotide phosphodiesterase activity in an islet cell tumor of the syrian hamster (1974) (10)
Inhibition of plasminogen activator secretion by cyclic AMP in a macrophage-like cell line. (1978) (10)
A specific cyclic guanosine 3':5'-monophosphate-binding protein in Caulobacter crescentus. (1975) (10)
Measurement of cyclic 3',5'-adenosine monophosphate synthesis in growing Escherichia coli. (1975) (10)
Characterization of the protein kinases in a transplantable islet cell tumor of the syrian hamster (1976) (9)
Modulation of Fc-receptor expression and Fc-mediated phagocytosis in variants of a macrophage-like cell line. (1981) (9)
Characterization of a calmodulin-binding protein that is deficient in trifluoperazine-resistant variants of the macrophage-like cell line J774. (1983) (8)
[112b] Fructose-1,6-diphosphatase: II. Candida utilis (1966) (8)
The effect of iodination upon the catalytic and regulatory activities of fructose 1,6-diphosphatase. (1967) (8)
Molecular Characterization of Cyclic AMP-Dependent Protein Kinases Derived from Bovine Heart and Human Erythrocytes (1974) (7)
Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells. (1993) (7)
Purification of a protein inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase from bovine myocardium by a non-denaturing procedure. (1977) (6)
Retention of endocrine function by an insulin-secreting pancreatic islet cell tumour from Syrain hamster through serial transplantation in nude mice. (1975) (6)
Regulation of the protein kinase activity of the human insulin receptor. (1987) (5)
Insulin Receptor as a Tyrosine Protein Kinase a (1986) (5)
[97a] Deoxyribose 5-phosphate aldolase: I. Lactobacillus plantarum (1966) (5)
Purification and distribution of a novel macrophage-specific calmodulin-binding glycoprotein. (1985) (3)
Genetic and Functional Studies of Continuous Macrophage-Like Cell Lines (1980) (3)
Banting lecture 1989. Structure and function of insulin receptors. (1989) (3)
Mn 2 +-binding properties of a recombinant protein-tyrosine kinase derived from the human insulin receptor ( conformational change / secondary structure / electron a ge resonance / drcular dichroism ) (3)
Activity stain for the detection of cyclic nucleotide phosphodiesterase in polyacrylamide gels. (1974) (3)
Phosphorylation of the active, A1 component of cholera toxin by protein kinase. (1976) (3)
INTERACTIONS BETWEEN INTERFERON AND CELLS OF THE IMMUNE SYSTEM (1982) (2)
Inhibition of adenosine 3':5'-monophosphate-dependent protein kinase: comparison of a protein inhibitor with polyanions and substrate analogs. (1977) (2)
The Insulin Receptor as a Tyrosine- Specific Protein Kinase (1985) (2)
Development of insulin responsiveness in 3T3-L1 preadipocytes (1979) (2)
Synthesis and degradation of cyclic 3',5'-adenosine monophosphate in frog erythrocytes. (1970) (2)
Purification of fructose-1, 6-diphosphatase from Polysphondylium pallidum. (1975) (1)
Protein phosphorylation : abstracts of papers presented at the Eighth Cold Spring Harbor Conference on Cell Proliferation, September 2-September 7, 1980 (1980) (1)
THE SUBUNIT STRUCTURE OF FRUCTOSE 1,6-DIPHOSPHATASE* (1966) (1)
Insulin stimulated phosphorylation of ribosomal protein s 6 in 3t3 l 1 pre adipocytes (1979) (1)
Protein tyrosine kinases, protein serine kinases, and the mechanism of action of insulin. (1986) (1)
An assay for protein activity on polyacrylamide gels. (1974) (0)
Insulin-Directed 32P-Incorporation into Ribosomal Protein S6 in 3T3-L1 Preadipocytes (1979) (0)
Development of β2 receptors and decline of β1 receptors during the differentiation of 3T3-L1 adipocytes (1981) (0)
[23] Preparation of adenylate cyclase from frog erythrocytes (1974) (0)
Isolation of a cyclic AMP dependent phosphoprotein from a glucagon responsive insulin secretory cell (1976) (0)
Effects of cytochalasins on the macrophage-like cell line J774.16 (1982) (0)
Activation ofS6kinase activity in3T3-L1 cells byinsulin and phorbol ester (1985) (0)
Preparation of adenylate cyclase from frog erythrocytes. (1974) (0)
Reconstitution ofan Insulin Signaling Pathway inXenopuslaevis Oocytes: Coexpression ofa MammalianInsulin Receptor andThree Different Mammalian HexoseTransporters (1990) (0)
Interconvertible Forms of a cAMP-Dependent Protein Kinase from Bovine Cardiac Muscle (1976) (0)
Immunoassay and immunopurification of macrophage calmodulin-binding protein. (1987) (0)
Effect of adenosine monophosphate on the reactivity of thiol groups of D-fructose 1,6-diphosphatase from rabbit liver. (1969) (0)
Protein Phosphorylation/Vol 8 Books A and B (1981) (0)
Chapter 22. The Structure-Activity Relationships of Adrenergic Compounds that act on Adenyl Cyclase of the Frog Erythrocyte (1971) (0)
Purified rat brain calcium-and phospholipid-dependent protein kinase phosphorylates ribosomal protein S 6 ( phorbol ester tumor promoters / insulin / growth factors / cAMP-dependent protein kinase / protein phosphorylation ) (1999) (0)
AN APPROACH TO THE STUDY OF PHOSPHOPROTEIN AND CYCLIC NUCLEOTIDE METABOLISM IN CULTURED CELL LINES WITH DIFFERENTIATED PROPERTIES1 (1979) (0)

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