Otmar Dieter Wiestler
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(Suggest an Edit or Addition)Otmar Dieter Wiestler's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The 2007 WHO Classification of Tumours of the Central Nervous System (2007) (12134)
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary (2016) (11090)
- Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. (2006) (2773)
- Embryonic stem cell-derived glial precursors: a source of myelinating transplants. (1999) (999)
- NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. (2009) (779)
- Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. (2009) (561)
- Erratum: The 2007 WHO classification of tumours of the central nervous system (Acta Neuropathol (2007) vol. 114 (97-109)) (2007) (557)
- International Society of Neuropathology‐Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading (2014) (514)
- NeuN: a useful neuronal marker for diagnostic histopathology. (1996) (482)
- Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91. (2000) (397)
- Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. (1997) (397)
- Hemangioblastomas of the central nervous system. A 10-year study with special reference to von Hippel-Lindau syndrome. (1989) (380)
- PTEN mutations in gliomas and glioneuronal tumors (1998) (366)
- Ammon's Horn Sclerosis: A Maldevelopmental Disorder Associated with Temporal Lobe Epilepsy (2002) (357)
- Destruction of neurons by cytotoxic T cells: A new pathogenic mechanism in rasmussen's encephalitis (2002) (351)
- Subsets of Glioblastoma Multiforme Defined by Molecular Genetic Analysis (1993) (348)
- Vascular Pathology in Alzheimer Disease: Correlation of Cerebral Amyloid Angiopathy and Arteriosclerosis/Lipohyalinosis with Cognitive Decline (2003) (327)
- Gangliogliomas: An Intriguing Tumor Entity Associated With Focal Epilepsies (2002) (327)
- p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. (1992) (320)
- Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus (1991) (316)
- Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. (2009) (303)
- Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein (2013) (292)
- Supratentorial gangliogliomas: Histopathologic grading and tumor recurrence in 184 patients with a median follow‐up of 8 years (2004) (286)
- Correlation of clinical and pathological features in surgically treated craniopharyngiomas. (1990) (261)
- Molecular Genetic Evidence for Subtypes of Oligoastrocytomas (1997) (252)
- Comparative Study of p53 Gene and Protein Alterations in Human Astrocytic Tumors (1993) (249)
- Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. (2001) (236)
- Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. (1992) (233)
- Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. (1992) (232)
- Focal Cortical Dysplasia of Taylor's Balloon Cell Type: A Clinicopathological Entity with Characteristic Neuroimaging and Histopathological Features, and Favorable Postsurgical Outcome (2002) (231)
- Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system (1993) (226)
- Central neurocytoma: histopathological variants and therapeutic approaches. (1992) (220)
- The natural history of Rasmussen's encephalitis. (2002) (219)
- p53 mutations in nonastrocytic human brain tumors. (1991) (211)
- Impact of Genotype and Morphology on the Prognosis of Glioblastoma (2002) (209)
- Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins (2008) (201)
- Surgical Pathology of Temporal Lobe Epilepsy. Experience with 216 Cases (1993) (195)
- Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations (2013) (194)
- Mechanisms of Disease: cancer stem cells—targeting the evil twin (2008) (190)
- Expression and distribution of vascular endothelial growth factor protein in human brain tumors (1997) (186)
- Molecular neuropathology of human mesial temporal lobe epilepsy (1999) (181)
- Diagnosis and staging of Rasmussen’s encephalitis by serial MRI and histopathology (2002) (179)
- Surgical treatment of temporal lobe epilepsy: clinical, radiological, and histopathological findings in 178 patients. (1995) (176)
- Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets. (2002) (172)
- European Code against Cancer 4th Edition: 12 ways to reduce your cancer risk. (2015) (169)
- Comprehensive Allelotype and Genetic Analysis of 466 Human Nervous System Tumors (2000) (166)
- Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors (2001) (165)
- Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation. (2004) (161)
- German Cancer Society Neuro‐Oncology Working Group NOA‐03 multicenter trial of single‐agent high‐dose methotrexate for primary central nervous system lymphoma (2002) (159)
- The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies (1999) (159)
- Activating L265P mutations of the MYD88 gene are common in primary central nervous system lymphoma (2011) (157)
- Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma (2011) (153)
- Surgical Pathology of Chronic Epileptic Seizure Disorders (1993) (150)
- Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell (2008) (150)
- Surgical treatment of neoplasms associated with medically intractable epilepsy. (1997) (149)
- Focal cortical dysplasia of Taylor's balloon cell type: Mutational analysis of the TSC1 gene indicates a pathogenic relationship to tuberous sclerosis (2002) (147)
- Phosphatidylinositol 3′-Kinase/AKT Signaling Is Activated in Medulloblastoma Cell Proliferation and Is Associated with Reduced Expression of PTEN (2006) (147)
- Ganglioglioma: a detailed histopathological and immunohistochemical analysis of 61 cases (2004) (143)
- Histogenesis and differentiation potential of central neurocytomas. (1991) (141)
- Correlated stage‐ and subfield‐associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy (2003) (138)
- Accumulation of wild type p53 protein in human astrocytomas. (1993) (137)
- Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme (1997) (133)
- O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors. (1984) (132)
- Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes (2010) (128)
- Perilesional neurochemical changes in focal epilepsies (1996) (127)
- The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing (2014) (127)
- Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. (2005) (120)
- Differential Expression of ICAM-1, VCAM-1 and Their Ligands LFA-1, Mac-1, CD43, VLA-4, and MHC Class II Antigens in Murine Toxoplasma Encephalitis: A Light Microscopic and Ultrastructural Immunohistochemical Study (1994) (115)
- Immunohistochemical distribution of metabotropic glutamate receptor subtypes mGluR1b, mGluR2/3, mGluR4a and mGluR5 in human hippocampus (1996) (112)
- Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain. (1997) (111)
- The 2007 WHO ClassiWcation of Tumours of the Central Nervous System (2007) (111)
- Patterns of differentiation in central neurocytoma. An immunohistochemical study of eleven biopsies. (1990) (110)
- Tobacco: deadly in any form or disguise (2006) (109)
- Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. (1999) (107)
- Tau EGFP embryonic stem cells: An efficient tool for neuronal lineage selection and transplantation (2002) (103)
- Glioneuronal Malformative Lesions and Dysembryoplastic Neuroepithelial Tumors in Pateints with Chroninc Pharmacoresistant Epilepsies (1995) (98)
- Distinct Expression Pattern of Microtubule‐Associated Protein‐2 in Human Oligodendrogliomas and Glial Precursor Cells (2001) (96)
- AFP/beta-HCG secreting CNS germ cell tumors: long-term outcome with respect to initial symptoms and primary tumor resection. Results of the cooperative trial MAKEI 89. (2005) (95)
- Expression of the Neurotrophin Receptor p75NTR in Medulloblastomas Is Correlated with Distinct Histological and Clinical Features: Evidence for a Medulloblastoma Subtype Derived from the External Granule Cell Layer (2000) (95)
- Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-All in Astrocytomas (2005) (92)
- Chromosomal imbalances in choroid plexus tumors. (2002) (91)
- Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus. (1999) (91)
- Trastuzumab and breast cancer. (2001) (91)
- Preradiation chemotherapy of children and young adults with malignant brain tumors: results of the German pilot trial HIT'88/'89. (1998) (91)
- Low Frequency of SV40, JC and BK Polyomavirus Sequences in Human Medulloblastomas, Meningiomas and Ependymomas (2000) (91)
- Interferon-gamma receptor-deficiency renders mice highly susceptible to toxoplasmosis by decreased macrophage activation. (1996) (88)
- Expression of αB‐crystallin in human brain tumors (1993) (85)
- Mutations of CARD11 but not TNFAIP3 may activate the NF-κB pathway in primary CNS lymphoma (2010) (85)
- Neural antigens in oligodendrogliomas and dysembryoplastic neuroepithelial tumors (1997) (83)
- Prognostic impact of TP53 mutations and P53 protein overexpression in supratentorial WHO grade II astrocytomas and oligoastrocytomas. (2002) (82)
- Cells with TP53 mutations in low grade astrocytic tumors evolve clonally to malignancy and are an unfavorable prognostic factor (1999) (82)
- Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin (2006) (82)
- Basal Caspase Activity Promotes Migration and Invasiveness in Glioblastoma Cells (2007) (81)
- Preservation of Calretinin‐immunoreactive Neurons in the Hippocampus of Epilepsy Patients with Ammon's Horn Sclerosis (1996) (81)
- An isomorphic subtype of long-term epilepsy-associated astrocytomas associated with benign prognosis (2004) (81)
- Microsatellite analysis of loss of heterozygosity on chromosomes 9q, 11 p and 17p in medulloblastomas (1994) (79)
- Characterization of five new cell lines derived from human primitive neuroectodermal tumors of the central nervous system. (1994) (78)
- Randomized, Prospective Double-Blinded Study Comparing 3 Different Doses of 5-Aminolevulinic Acid for Fluorescence-Guided Resections of Malignant Gliomas (2017) (78)
- Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. (2010) (77)
- [The new WHO classification of tumors of the nervous system 2000. Pathology and genetics]. (2002) (76)
- Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. (2014) (75)
- Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme (1996) (74)
- Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. (2005) (73)
- Patterns of differentiation in central neurocytoma (1990) (73)
- Impact of surgery, chemotherapy and irradiation on long term outcome of intracranial malignant non-germinomatous germ cell tumors: results of the German Cooperative Trial MAKEI 89. (2004) (73)
- A rapid and non‐radioactive PCR based assay for the detection of allelic loss in human gliomas (1993) (71)
- Evidence for developmental precursor lesions in epilepsy‐associated glioneuronal tumors (1999) (70)
- Interphase Cytogenetic Analysis of Lymphoma‐Associated Chromosomal Breakpoints in Primary Diffuse Large B‐Cell Lymphomas of the Central Nervous System (2002) (69)
- Microtubule-associated protein-2 immunoreactivity: a useful tool in the differential diagnosis of low-grade neuroepithelial tumors (2004) (68)
- Chromosomal imbalances and partial uniparental disomies in primary central nervous system lymphoma (2009) (67)
- Alternative splicing of the βA4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients (1991) (66)
- Deletions on the long arm of chromosome 17 in pilocytic astrocytoma (1993) (64)
- Functional network integration of embryonic stem cell-derived astrocytes in hippocampal slice cultures (2003) (64)
- Transcriptional profiling in human epilepsy: expression array and single cell real-time qRT-PCR analysis reveal distinct cellular gene regulation (2002) (64)
- An increase of hippocampal calretinin-immunoreactive neurons correlates with early febrile seizures in temporal lobe epilepsy (1999) (64)
- Postsurgical outcome of children and adolescents with medically refractory frontal lobe epilepsies (2001) (64)
- Dynamics of the intracerebral and splenic cytokine mRNA production in Toxoplasma gondii-resistant and -susceptible congenic strains of mice. (1995) (62)
- Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1 (2012) (62)
- Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF‐dependent transcription in medulloblastomas (2007) (61)
- Neurochemical Profile of Glioneuronal Lesions from Patients with Pharmacoresistant Focal Epilepsies (1995) (61)
- Subtype‐specific expression and genetic alterations of the chemokinereceptor gene CXCR4 in medulloblastomas (2005) (60)
- Interleukin-10 downregulates the intracerebral immune response in chronic Toxoplasma encephalitis (1997) (60)
- Expression of the CD34 antigen in pleomorphic xanthoastrocytomas (2003) (59)
- Toxoplasma encephalitis in congenic B10 and BALB mice: impact of genetic factors on the immune response (1994) (59)
- The impact of argyrophilic grain disease on the development of dementia and its relationship to concurrent Alzheimer's disease‐related pathology (2005) (59)
- Intracranial venous hypertension and the effects of venous outflow obstruction in a rat model of arteriovenous fistula. (1991) (58)
- Indications for a tumor suppressor gene at 22q11 involved in the pathogenesis of ependymal tumors and distinct from hSNF5/INI1 (2001) (58)
- Genetic Alterations Commonly Found in Diffusely Infiltrating Cerebral Gliomas Are Rare or Absent in Pleomorphic Xanthoastrocytomas (2002) (56)
- Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria. (2010) (56)
- Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma (2008) (56)
- Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer (2005) (55)
- Fatal myeloencephalopathy due to accidental intrathecal vincristin administration: a report of two cases. (2001) (54)
- Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF (1999) (53)
- The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway (2008) (53)
- Altered distribution of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit GluR2(4) and the N-methyl-d-aspartate receptor subunit NMDAR1 in the hippocampus of patients with temporal lobe epilepsy (1996) (52)
- A Rapid and Sensitive Protocol for Competitive Reverse Transcriptase (cRT) PCR Analysis of Cellular Genes (1998) (52)
- Neuronal loss and gliosis of the amygdaloid nucleus in temporal lobe epilepsy (1997) (52)
- Systemic immunization induces protective CD4+ and CD8+ T cell‐mediated immune responses in murine Listeria monocytogenes meningoencephalitis (1995) (51)
- A device for processing large acrylamide gels. (1994) (51)
- The changing pattern of human immunodeficiency virus-associated cerebral toxoplasmosis: a study of 46 postmortem cases (2004) (51)
- Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology. (2006) (51)
- Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer. (1991) (48)
- Loss of heterozygosity on chromosome 1 in human hepatoblastoma (1996) (48)
- The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial. (1995) (48)
- Surgical pathology of chronic epileptic seizure disorders: experience with 63 specimens from extratemporal corticectomies, lobectomies and functional hemispherectomies (2004) (44)
- Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche. (2019) (44)
- Expression of the epidermal growth factor receptor in astrocytic tumours is specifically associated with glioblastoma multiforme (2005) (44)
- Transcriptional Profiling of the Nuclear Factor-&kgr;B Pathway Identifies a Subgroup of Primary Lymphoma of the Central Nervous System With Low BCL10 Expression (2007) (44)
- Microsatellite Instability in Pediatric and Adult High‐grade Gliomas (2007) (42)
- Regulation of Microglia by CD4+ and CD8+ T Cells: Selective Analysis in CD45‐congenic Normal and Toxoplasma gondii‐infected Bone Marrow Chimeras (2001) (42)
- Developmental expression of two forms of pp60c-src in mouse brain (1988) (42)
- Clustering of features and genetics of von Hippel-Lindau syndrome (1991) (42)
- Molecular profiling of temporal lobe epilepsy: comparison of data from human tissue samples and animal models (2004) (41)
- Clonality of multiple meningiomas (1997) (40)
- Entry routes of malignant lymphoma into the brain and eyes in a mouse model. (2001) (40)
- In situ-RT and immunolaser microdissection for mRNA analysis of individual cells isolated from epilepsy-associated glioneuronal tumors (2004) (40)
- Clinical relevance of amygdala sclerosis in temporal lobe epilepsy. (1999) (39)
- A model for primitive neuroectodermal tumors in transgenic neural transplants harboring the SV40 large T antigen. (1994) (38)
- Distribution of voltage-dependent calcium channel beta subunits in the hippocampus of patients with temporal lobe epilepsy (1999) (38)
- Absence of immunoglobulin class switch in primary lymphomas of the central nervous system. (2005) (38)
- PCR identification of HIV‐1 DNA sequences in brain tissue of patients with AIDS encephalopathy (1993) (37)
- Neuropathology of a human hippocampus following long-term treatment with vigabatrin: lack of microvacuoles (1990) (37)
- Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors (2007) (36)
- Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer’s disease (1997) (36)
- Array-based DNA methylation profiling of primary lymphomas of the central nervous system (2009) (36)
- Expression of alpha B-crystallin in human brain tumors. (1993) (35)
- Expression of variant CD44 epitopes in human astrocytic brain tumors (1995) (35)
- An altered form of pp60c-src is expressed primarily in the central nervous system (1987) (34)
- Molecular analysis of the lissencephaly gene 1 (LIS‐1) in medulloblastomas (1996) (34)
- SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas (2007) (32)
- Oncogene complementation in fetal brain transplants. (1992) (32)
- Tuberous sclerosis-like lesions in epileptogenic human neocortex lack allelic loss at the TSC1 and TSC2 regions (1996) (31)
- Molecular Characterization of BCL6 Breakpoints in Primary Diffuse Large B‐cell Lymphomas of the Central Nervous System Identifies GAPD as Novel Translocation Partner (2003) (31)
- Apoptosis and apoptosis-related gene products in primary non-Hodgkin’s lymphoma of the central nervous system (1998) (31)
- Interferon-γ antagonizes transforming growth factor-β 2-mediated immunosuppression in murine Toxoplasma encephalitis (1998) (31)
- The 2007 WHO classification of tumours of the central nervous system (2007) (30)
- Location of N-methyl-N'-nitro-N-nitrosoguanidine-induced gastrointestinal tumors correlates with thiol distribution. (1983) (30)
- The apolipoprotein E ε4 allele is not associated with early onset temporal lobe epilepsy (1997) (30)
- Genomic deletions in the BRCA1, BRCA2 and TP53 regions associate with low expression of the estrogen receptor in sporadic breast carcinoma (1997) (30)
- Evidence for Subarachnoid Spread in the Development of Multiple Meningiomas (1995) (29)
- Molecular Neuropathology of Astrocytic Brain Tumors (1997) (29)
- Intracranial venous hypertension and the effects of venous outflow obstruction in a rat model of arteriovenous fistula (1991) (28)
- An experimental model for infiltration of malignant lymphoma to the eye and brain (1997) (28)
- Astrocytic gliomas: characterization on a molecular genetic basis. (1994) (28)
- 5'-Nucleotidase activity indicates sites of synaptic plasticity and reactive synaptogenesis in the human brain. (1999) (27)
- Induction of rat liver O6-alkylguanine-DNA alkyltransferase following whole body X-irradiation. (1986) (27)
- Primary brain tumors differ in their expression of octamer deoxyribonucleic acid-binding transcription factors from long-term cultured glioma cell lines. (1994) (25)
- Local immunotherapy of glioma patients with a combination of 2 bispecific antibody fragments and resting autologous lymphocytes: evidence for in situ t-cell activation and therapeutic efficacy. (2001) (25)
- Cancer Core Europe: a consortium to address the cancer care-cancer research continuum challenge. (2014) (24)
- Angiogenic activity of the K-fgf/hst oncogene in neural transplants. (1992) (24)
- Molecular genetic studies in medulloblastomas: evidence for tumor suppressor genes at the chromosomal regions 1q31-32 and 17p13. (1997) (24)
- VH gene analysis of primary CNS lymphomas (2005) (24)
- Mutational and expression analysis of the reelin pathway components CDK5 and doublecortin in gangliogliomas (2002) (23)
- Altered distribution of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit GluR2(4) and the N-methyl-D-aspartate receptor subunit NMDAR1 in the hippocampus of patients with temporal lobe epilepsy. (1996) (23)
- Absence of simian virus 40 DNA sequences in primary central nervous system lymphoma in HIV-negative patients (2004) (22)
- Distinct Allelic Variants of TSC1 and TSC2 in Epilepsy-Associated Cortical Malformations Without Balloon Cells (2005) (22)
- The apolipoprotein E epsilon 4 allele is not associated with early onset temporal lobe epilepsy. (1997) (22)
- Primary manifestation of Hodgkin’s disease in the central nervous system (1998) (20)
- Type and frequency of p53 mutations in tumors of the nervous system and its coverings. (1994) (20)
- Analysis of chromosomal instability in focal cortical dysplasia of Taylor’s balloon cell type (2004) (20)
- Functional genomics in experimental and human temporal lobe epilepsy: powerful new tools to identify molecular disease mechanisms of hippocampal damage. (2002) (19)
- [HIT-LGG: effectiveness of carboplatin-vincristine in progressive low-grade gliomas of childhood--an interim report]. (2000) (19)
- Tumor induction by ras and myc oncogenes in fetal and neonatal brain: modulating effects of developmental stage and retroviral dose (2004) (19)
- Hippocampal loss of the GABAA receptor α1 subunit in patients with chronic pharmacoresistant epilepsies (2004) (19)
- Analysis of the TP53 gene in laser-microdissected glioblastoma vasculature (2003) (18)
- Yunis-Varon syndrome: evidence for a lysosomal storage disease. (2000) (18)
- Distribution and immunoreactivity of cerebral micro-hamartomas in bilateral acoustic neurofibromatosis (neurofibromatosis 2) (2004) (17)
- Troglitazone-mediated sensitization to TRAIL-induced apoptosis is regulated by proteasome-dependent degradation of FLIP and ERK1/2-dependent phosphorylation of BAD (2008) (17)
- Plaque formation in brain transplants exposed to human β-amyloid precursor protein 695 (1996) (16)
- Regional distribution of the AMPA glutamate receptor subunits GluR2(4) in human hippocampus (1995) (16)
- Human herpes virus-8 is not associated with primary central nervous system lymphoma in HIV-negative patients (2001) (15)
- Neuropathology and pathogenesis of HIV encephalopathies. (1992) (15)
- Migration and Differentiation of Myogenic Precursors Following Transplantation into the Developing Rat Brain (2003) (15)
- Extracerebral intracranial glioneural hamartoma with extension into the parapharyngeal space. (1995) (15)
- Molecular genetic analysis as a tool for evaluating stereotactic biopsies of glioma specimens. (1999) (15)
- [Revised WHO classification and new developments in diagnosis of central nervous system tumors]. (1995) (14)
- DNA methylation in maternal, fetal and neonatal rat tissues following perinatal administration of procarbazine (2004) (14)
- Cellular and Molecular Aspects of Neurocarcinogenesis (1990) (14)
- A new approach to the molecular basis of neoplastic transformation in the brain (1992) (13)
- Chromosomal imbalances and DNA amplifications in SV40 large T antigen-induced primitive neuroectodermal tumor cell lines of the rat. (1999) (13)
- Interferon-gamma antagonizes transforming growth factor-beta2-mediated immunosuppression in murine Toxoplasma encephalitis. (1998) (12)
- New developments in the pathology of skull base tumors (2001) (12)
- Hippocampal loss of N-methyl-D-aspartate receptor subunit 1 mRNA in chronic temporal lobe epilepsy (2004) (12)
- Status Report on the European Clinical Trial of BNCT at Petten (EORTC Protocol 11961) (2001) (12)
- Preferential Expression of Truncated Isoforms of FOXP1 in Primary Central Nervous System Lymphoma (2009) (10)
- Methylation Profiling Identifies Epigenetic Markers for High-grade Gliomas. (2004) (10)
- Activation of the innate immune system in murine congenital Toxoplasma encephalitis (1994) (10)
- Identification of amplified genes from SV40 large T antigen-induced rat PNET cell lines by subtractive cDNA analysis and radiation hybrid mapping (2001) (9)
- Analysis of the TSC2 gene in human medulloblastoma (2001) (9)
- Cowen disease and dysplastic gangliocytoma of the cerebellum/Lhermitte-Duclos disease (2000) (9)
- Evolutionary expression of the neuronal form of the src protein in the brain. (1989) (9)
- Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients. (1991) (9)
- Von Hippel-Lindau disease: a syndrome providing insights into growth control and tumorigenesis. (1994) (8)
- Long-term follow-up in 39 patients with an ependymoma after surgery and irradiation. (1992) (8)
- Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea. (2016) (8)
- Complementary tumor induction in neural grafts exposed to N-ethyl-N-nitrosourea and an activated myc gene. (1993) (8)
- Interorgan shift of nitrosamine metabolism by dietary ethanol. (1987) (7)
- HIV encephalopathy: incidence, definition and pathogenesis. Results of a Swiss collaborative study. (1991) (7)
- Malformative and neoplastic glioneuronal lesions in patients with chronic pharmacoresistant epilepsies. (1999) (7)
- Oncogene transfer into the brain. (1994) (7)
- Dexamethasone selectively regulates the activity of enzymatic markers of cerebral endothelial cell lines (1992) (7)
- Small vessel lesions related to Amyloid Angiopathy (CAA) and arteriosclerosis/ lipohyalinosis (AS/LH) are associated with Alzheimer's disease (2003) (6)
- Quantitative analysis of NF1 and OMGP gene transcripts in sporadic gliomas, sporadic meningiomas and neurofibromatosis type 1-associated plexiform neurofibromas (1999) (6)
- Brainstem lesion revealed by MRI in a case of Leigh's disease with respiratory failure (2005) (6)
- Progressive loss of neuronal src protein in postnatal weaver and staggerer cerebellum. (1988) (5)
- Immunohistochemical Assessment of Differentiation and DNA Replication in Human Brain Tumors (1989) (5)
- Tumour induction in fetal brain transplants exposed to the viral oncogenes polyoma middle T and v-src. (1989) (5)
- Peripheral immunization against malignant rat glioma can induce effective antitumor immunity in the brain. (1995) (5)
- Rapid progress in the field of infectious and autoimmune disorders of the nervous system. (1995) (4)
- Sensitive two-site sandwich enzyme immunoassay with antipeptide antibodies for detection of viral antigens. (1988) (4)
- Allele‐specific losses of heterozygosity on chromosomes 1 and 17 revealed by whole genome scan of ethylnitrosourea‐induced gliomas of BDIX × BDIV hybrid rats (2000) (4)
- Serum erythropoietin levels in von Hippel-Lindau syndrome. (1991) (4)
- Cancer stem cells : Novel concepts and prospects for tumor therapy (2007) (4)
- Advances in Brief p 53 Mutations in Nonastrocytic Human Brain Tumors ' (2006) (3)
- Nafenopin-induced rat liver peroxisome proliferation reduces DNA methylation by N-nitrosodimethylamine in vivo. (1985) (3)
- Purification and characterization of 6-pyruvoyl tetrahydropterin synthase from human pituitary gland. (1992) (3)
- Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy (2004) (3)
- Determining the glioma CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide methylation data in the biomarker cohort of the NOA-04 trial. (2014) (3)
- Curbing tobacco's toll starts with the professionals: World No Tobacco Day (2005) (3)
- Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors (1994) (3)
- Leiomyosarcoma of the skull base-a diagnostic challenge. (1992) (2)
- [Differentiation of medulloblastoma: immunohistochemistry of 247 cases from the therapy trial SIOP/GPO MED 84]. (1988) (2)
- Growth control and neoplastic transformation in the brain. (1991) (2)
- Developmental Neuro-Oncogenesis in Experimental Animals (1982) (2)
- [Neuropathologic findings in chronic epilepsy]. (1995) (2)
- [The PEA-15 protein induces resistance against glucose deprivation-induced cell death via the ERK/MAP kinase pathway]. (2007) (2)
- [The anti-diabetic drug troglitazone sensitizes colon cancer cells to TRAIL-induced apoptosis by down-regulating FLIP]. (2007) (2)
- [Induction of primitive neuroectodermal tumors by oncogene complementation]. (1990) (2)
- [Biochemical study of the position specificity of rat gastrointestinal cancer induced by MNNG]. (1984) (1)
- Analysis of a polymorphism in the tuberous sclerosis (TSC2) gene does not predispose to schizophrenia (1998) (1)
- Migratory potential of transplantable neural tumor cell lines (1999) (1)
- Pituicytoma: a new brain tumor entity? (2004) (1)
- Involvement of thiols in gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine: biochemical and autoradiographic studies. (1984) (1)
- [Morphological findings in temporal lobe epilepsy: experience with 216 consecutive surgical specimens]. (1994) (1)
- New developments and controversies in the neuropathology of malignant gliomas. (1999) (1)
- Tuberous sclerosis and tuberin: What do we learn from in situ localization data in the human brain? (1996) (1)
- Persistence of alkylated sites in DNA and its biological significance. (1983) (1)
- Metabolism of N-nitrosodimethylamine and N-nitrosomethylbenzylamine in domestic fowls: DNA alkylation and potential target sites for carcinogenicity. (1986) (1)
- Pathology and molecular classification (2004) (1)
- Repair of O6-alkylguanine in cellular DNA: significance for tumour induction and chemotherapy (1984) (1)
- DNA methylation by N-nitrosomethylbenzylamine in target and non-target tissues of laboratory rodents. Comparison with carcinogenicity. (1984) (1)
- [Astrocytoma in a premature twin]. (1987) (0)
- Molecular Neuropathology and 49th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (2004) (0)
- DISTAL AXONOPATHY IN THE CEREBELLUM OF MTCE FOLLOWING CHRONIC ADMINISTRATION OF PIIENYTOIN (1985) (0)
- Soluble forms of A beta alter layer III pyramidal neurons with a ramified dendritic tree in APP23-transgenic mice (2004) (0)
- P3-186 Concurrent Alzheimer's disease-related pathology lowers the threshold for developing dementia in argyrophilic grain disease (2004) (0)
- Molecular Diagnostics - Today and Tomorrow (2012) (0)
- 5: Cancer research from the bench to the bedside (2014) (0)
- Differential expression of cell adhesion molecules and MHC class II antigens in murine Toxoplasma encephalitis (1994) (0)
- Foreword (1995) (0)
- SOX18 is a target gene of the Shh-Ptc pathway in murine cerebellar granule cell precursors and is highly expressed in human desmoplastic medulloblastomas (2004) (0)
- Soluble Aβ in APP23 transgenic mice induces degeneration of layer III pyramidal neurons with ramified dendritic tree (2004) (0)
- [Progression-associated gene regions in astrocytomas: a candidate locus on chromosome 19q]. (1994) (0)
- Research for the Sake of the Patients (2006) (0)
- Advances in Brief p 53 Mutations Are Associated with 17 p Allelic Loss in Grade II and Grade III Astrocytoma 1 (2006) (0)
- Health eff ects of ionising radiation from diagnostic CT (2006) (0)
- Introduction: Pathogenesis and Pathophysiology of Focal Epilepsies (2002) (0)
- Synthesis and Neoangiogenesis ( Flt-1 ) / Vascular Endothelial Growth Factor Receptor-1 Astrocytomas Is Associated with Fms-like Tyrosine Kinase-1 Expression of the Ets-1 Transcription Factor in Human Updated (1999) (0)
- 438 APP 695 induces plaque formation in rat brain transplants (1996) (0)
- Postersession I: Endokrinologie (1984) (0)
- The extent of small vessel lesions is associated with Alzheimer disease (AD) (2003) (0)
- A Model for the Molecular Pathogenesis of Astrocytic Gliomas (1996) (0)
- neuroRAD 2019 (2019) (0)
- Zülch symposium on growth control and neoplastic transformation in the brain, Goslar, Germany, April 28, 1991-May 1, 1991. (1991) (0)
- Meeting Report (1973) (0)
- Genome wide methylation analysis of gliomas by a microarray based technology (2004) (0)
- Quality management in neuropathology. (2001) (0)
- The Internationalization Strategy of the Helmholtz Association (2017) (0)
- Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction (2020) (0)
- Results Expression of Active Caspase-3 in Brain Tumors In vivo (2007) (0)
- Abstract 4807:Brafmutations initiate the development of rat gliomas induced by postnatal exposure toN-ethyl-N-nitrosourea (ENU) (2017) (0)
- Extracellular matrix proteins control the growth of cerebellar medulloblastoma cells (2004) (0)
- Opening Event of the Athens Comprehensive Cancer Center (ACCC) (2017) (0)
- Oncogene Complementation in Fetal Brain Transplants1 (2006) (0)
- Microarray analysis of differential methylation during glioma progression (2004) (0)
- The M6P/IGF2-receptor gene shows allelic loss but is not mutated in ependymomas (2004) (0)
- Comprar Cancer Stem Cells · Novel Concepts and Prospects for Tumor Therapy | Wiestler, Otmar D. | 9783540708520 | Springer (2007) (0)
- Molecular Neuropathology and 49th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (2004) (0)
- [Cancer research at the transition from bench to bedside]. (2006) (0)
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What Schools Are Affiliated With Otmar Dieter Wiestler?
Otmar Dieter Wiestler is affiliated with the following schools:
