Outi Vaarala
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Finnish immunologist, Senior Vice President for Research and Development , professor/research professor
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Immunology
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(Suggest an Edit or Addition)Outi Vaarala's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. (2015) (825)
- Environmental triggers and determinants of type 1 diabetes. (2005) (513)
- GAD treatment and insulin secretion in recent-onset type 1 diabetes. (2008) (503)
- AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland (2012) (476)
- The “Perfect Storm” for Type 1 Diabetes (2008) (475)
- Fecal Microbiota Composition Differs Between Children With β-Cell Autoimmunity and Those Without (2013) (472)
- Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosus (1993) (431)
- Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy. (2004) (350)
- Environmental factors in the etiology of type 1 diabetes. (2002) (334)
- Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men. (1995) (325)
- Antibody against oxidized low-density lipoprotein predicting myocardial infarction. (1994) (318)
- IL-17 Immunity in Human Type 1 Diabetes (2010) (289)
- Dietary intervention in infancy and later signs of beta-cell autoimmunity. (2010) (235)
- Anticardiolipin response in acute infections. (1986) (231)
- A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children. (2004) (225)
- Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2 (2015) (223)
- Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination (2014) (220)
- IL‐23/IL‐17 immunity as a hallmark of Crohn's disease (2008) (200)
- Probiotics in infancy induce protective immune profiles that are characteristic for chronic low‐grade inflammation (2008) (188)
- Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes. (1999) (184)
- Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae (2002) (168)
- Immunologic activity in the small intestinal mucosa of pediatric patients with type 1 diabetes. (2003) (162)
- Induction of inflammation as a possible mechanism of probiotic effect in atopic eczema-dermatitis syndrome. (2005) (159)
- Functional properties of complement factor H‐related proteins FHR‐3 and FHR‐4: binding to the C3d region of C3b and differential regulation by heparin (1999) (152)
- Patterns of β-Cell Autoantibody Appearance and Genetic Associations During the First Years of Life (2013) (150)
- Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial. (2014) (145)
- Infections in Infants Fed Formula Supplemented With Bovine Milk Fat Globule Membranes (2015) (145)
- Antibodies to Prothrombin Imply a Risk of Myocardial Infarction in Middle-Aged Men (1996) (144)
- Immunological effects of probiotics with special reference to lactobacilli (2003) (136)
- Relation of inflammation to vascular function in patients with coronary heart disease. (2000) (123)
- Psychological stress may induce diabetes-related autoimmunity in infancy. (2005) (122)
- Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study (2005) (120)
- Epithelial IL‐6 trans‐signaling defines a new asthma phenotype with increased airway inflammation (2019) (119)
- Development of immune response to cow's milk proteins in infants receiving cow's milk or hydrolyzed formula. (1995) (117)
- HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy. (2015) (111)
- Is the origin of type 1 diabetes in the gut? (2012) (110)
- Leaking gut in type 1 diabetes (2008) (110)
- Removal of Bovine Insulin From Cow's Milk Formula and Early Initiation of Beta-Cell Autoimmunity in the FINDIA Pilot Study. (2012) (108)
- Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group. (2000) (108)
- Cellular Immune Response to Cow's Milk β-Lactoglobulin in Patients With Newly Diagnosed IDDM (1996) (97)
- Helsinki alert of biodiversity and health (2015) (96)
- Enhanced levels of cow’s milk antibodies in infancy in children who develop type 1 diabetes later in childhood (2008) (95)
- Antiphospholipid and antinuclear antibodies in patients with epilepsy or new-onset seizure disorders. (2000) (94)
- The Increased Risk for Autoimmune Diseases in Patients with Eating Disorders (2014) (94)
- Neonatal Type I diabetes associated with maternal echovirus 6 infection: a case report (2000) (93)
- Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial (2018) (93)
- Infiltration of forkhead box P3‐expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes (2008) (93)
- High Antibody Levels to Prothrombin Imply a Risk of Deep Venous Thrombosis and Pulmonary Embolism in Middle-aged Men (1997) (93)
- Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk (2014) (91)
- Glutamate Decarboxylase–Reactive Peripheral Blood Lymphocytes From Patients With IDDM Express Gut-Specific Homing Receptor α4β7-Integrin (1997) (88)
- Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus. (1996) (86)
- Short duration of breast-feeding as a risk-factor for β-cell autoantibodies in 5-year-old children from the general population (2007) (84)
- Transforming growth factor-beta1 in mothers' colostrum and immune responses to cows' milk proteins in infants with cows' milk allergy. (1999) (82)
- Antiphospholipid antibodies and myocardial infarction (1998) (80)
- Consumption of unprocessed cow's milk protects infants from common respiratory infections. (2015) (80)
- Rotavirus infections and development of diabetes‐associated autoantibodies during the first 2 years of life (2002) (79)
- IgA Antibodies, TGF-β1 and -β2, and Soluble CD14 in the Colostrum and Development of Atopy by Age 4 (2005) (78)
- ω-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk. (2016) (77)
- Altered Fecal Microbiota in Paediatric Inflammatory Bowel Disease. (2015) (75)
- No difference in platelet activation or inflammation markers after diets rich or poor in vegetables, berries and apple in healthy subjects (2004) (75)
- Human Intestinal Microbiota and Type 1 Diabetes (2013) (75)
- Antiphospholipid Antibodies and Atherosclerosis (1996) (73)
- Breast-feeding and the development of cows' milk protein allergy. (2000) (73)
- Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B. (2000) (72)
- Joint effects of C-reactive protein and other risk factors on acute coronary events. (2001) (71)
- Lupus anticoagulant and the skin. A longterm follow-up study of SLE patients with special reference to histopathological findings. (1991) (71)
- Soluble immunoglobulin A in breast milk is inversely associated with atopic dermatitis at early age: the PASTURE cohort study (2014) (71)
- High level of fecal calprotectin at age 2 months as a marker of intestinal inflammation predicts atopic dermatitis and asthma by age 6 (2015) (70)
- Dietary risk factors for the emergence of type 1 diabetes-related autoantibodies in 2½-year-old Swedish children (2006) (69)
- Th1/Th17 Plasticity Is a Marker of Advanced β Cell Autoimmunity and Impaired Glucose Tolerance in Humans (2015) (67)
- Probiotics for the Prevention of Beta Cell Autoimmunity in Children at Genetic Risk of Type 1 Diabetes—the PRODIA Study (2005) (63)
- IL-17-high asthma with features of a psoriasis immunophenotype. (2019) (62)
- Affinity‐purified cardiolipin‐binding antibodies show heterogeneity in their binding to oxidized low‐density lipoprotein (1996) (62)
- Children With Newly Diagnosed IDDM Have Increased Levels of Antibodies to Bovine Serum Albumin But Not to Ovalbumin (1994) (61)
- Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients. (2006) (61)
- The Gut Immune System and Type 1 Diabetes (2002) (61)
- Antibodies to oxidised LDL (2000) (60)
- Pre and probiotics in the prevention and treatment of food allergy (2008) (58)
- Scientific rationale for the Finnish Allergy Programme 2008–2018: emphasis on prevention and endorsing tolerance (2009) (58)
- Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes. (2009) (57)
- Cytokine and chemokine receptor profile of peripheral blood mononuclear cells during treatment with infliximab in patients with active rheumatoid arthritis (2004) (55)
- Gut and the Induction of Immune Tolerance in Type 1 Diabetes (1999) (53)
- Interaction of enterovirus infection and cow's milk‐based formula nutrition in type 1 diabetes‐associated autoimmunity (2012) (53)
- No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix Vaccination Campaign in Finland (2013) (53)
- Increased FOXP3 expression in small-bowel mucosa of children with coeliac disease and type I diabetes mellitus (2009) (53)
- Enteral virus infections in early childhood and an enhanced type 1 diabetes-associated antibody response to dietary insulin. (2006) (52)
- Innate immune responses in Lyme borreliosis: enhanced tumour necrosis factor‐α and interleukin‐12 in asymptomatic individuals in response to live spirochetes (2005) (50)
- The gut as a regulator of early inflammation in type 1 diabetes (2011) (50)
- Autoantibodies to modified LDLs and other phospholipid–protein complexes as markers of cardiovascular diseases (2000) (49)
- Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus. (2014) (48)
- Effect of coincident enterovirus infection and cows' milk exposure on immunisation to insulin in early infancy (2002) (48)
- Peptidylarginine deiminase, the arginine to citrulline converting enzyme, is frequently recognized by sera of patients with rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren syndrome (2003) (46)
- Activation of group 2 innate lymphoid cells after allergen challenge in asthmatic patients. (2019) (46)
- Responses of coxsackievirus B4-specific T-cell lines to 2C protein-characterization of epitopes with special reference to the GAD65 homology region. (2001) (45)
- Rotavirus Vaccination and the Risk of Celiac Disease or Type 1 Diabetes in Finnish Children at Early Life (2017) (44)
- IgA antibodies, TGF-beta1 and -beta2, and soluble CD14 in the colostrum and development of atopy by age 4. (2005) (44)
- Insulin Treatment in Patients With Type 1 Diabetes Induces Upregulation of Regulatory T-Cell Markers in Peripheral Blood Mononuclear Cells Stimulated With Insulin In Vitro (2006) (43)
- Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus (2019) (43)
- Urinary transforming growth factor-beta1 and alpha1-microglobulin in children and adolescents with type 1 diabetes. (2000) (42)
- Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity (2017) (42)
- Venous Thrombosis Associated with Lupus Anticoagulant and Anticardiolipin Antibodies (1988) (41)
- Enterovirus infection may induce humoral immune response reacting with islet cell autoantigens in humans (2003) (41)
- Dynamics of IFN-β Responses During Respiratory Viral Infection: Insights for Therapeutic Strategies. (2019) (39)
- Altered Activation of Innate Immunity Associates with White Matter Volume and Diffusion in First-Episode Psychosis (2015) (39)
- Maturation of Gut Microbiota and Circulating Regulatory T Cells and Development of IgE Sensitization in Early Life (2019) (38)
- Decreased in vitro type 1 immune response against coxsackie virus B4 in children with type 1 diabetes. (2005) (38)
- Infiltration of Foxp3- and Toll-like Receptor-4–positive Cells in the Intestines of Children With Food Allergy (2010) (36)
- Up‐regulation of small intestinal interleukin‐17 immunity in untreated coeliac disease but not in potential coeliac disease or in type 1 diabetes (2012) (35)
- Immune Response to Glycated and Oxidized LDL in IDDM Patients With and Without Renal Disease (1997) (35)
- Gut microbiota and type 1 diabetes. (2012) (34)
- Environmental factors related to the induction of beta‐cell autoantibodies in 1‐yr‐old healthy children (2005) (33)
- Antibodies to human heat shock protein 60, hypertension and dyslipidemia. A study of joint effects on coronary risk. (2003) (33)
- Antibodies to prothrombin crossreact with plasminogen in patients developing myocardial infarction (1998) (33)
- Higher prevalence of autoantibodies to insulin and GAD65 in Swedish compared to Lithuanian children with type 1 diabetes. (2006) (32)
- Maternal diet during pregnancy and lactation and cow’s milk allergy in offspring (2016) (32)
- Is It Dietary Insulin? (2006) (32)
- Combined T regulatory cell and Th2 expression profile identifies children with cow's milk allergy. (2010) (32)
- The effect of gluten-free diet on Th1–Th2–Th3-associated intestinal immune responses in celiac disease (2011) (32)
- Vaccinations May Induce Diabetes‐Related Autoantibodies in One‐Year‐Old Children (2003) (31)
- CCR3, CCR5, interleukin 4, and interferon-gamma expression on synovial and peripheral T cells and monocytes in patients with rheumatoid arthritis. (2003) (31)
- Association of Mannan-Binding Lectin Deficiency with Venous Bypass Graft Occlusions in Patients with Coronary Heart Disease (2002) (31)
- Simvastatin Protects against Multiple Low-Dose Streptozotocin-Induced Type 1 Diabetes in CD-1 Mice and Recurrence of Disease in Nonobese Diabetic Mice (2007) (31)
- Glutamate decarboxylase-reactive peripheral blood lymphocytes from patients with IDDM express gut-specific homing receptor alpha4beta7-integrin. (1997) (31)
- Effective Inhibition of Cardiolipin‐Binding Antibodies in Gram‐Negative Infections by Bacterial Lipopolysaccharide (1988) (31)
- Poor In Vitro Maturation and Pro‐Inflammatory Cytokine Response of Dendritic Cells in Children at Genetic Risk of Type 1 Diabetes (2004) (31)
- Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study (2005) (30)
- Gain-of-function CEBPE mutation causes non-canonical autoinflammatory inflammasomopathy. (2019) (30)
- Significance of false positive syphilis reactions and anticardiolipin antibodies in a nationwide series of pregnant women. (1988) (30)
- Increased secretion of TGF‐β1 by peripheral blood mononuclear cells from patients with Type 1 diabetes mellitus with diabetic nephropathy (2001) (30)
- Increased IFN‐γ secretion from duodenal biopsy samples in delayed‐type cow's milk allergy (2005) (30)
- Altered Phenotype of Peripheral Blood Dendritic Cells in Pediatric Type 1 Diabetes (2012) (29)
- Serologic response against cardiolipin and enterobacterial common antigen in young patients with acute myocardial infarction. (1989) (29)
- Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus (2015) (29)
- Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity (2020) (28)
- Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells (2018) (28)
- Binding profiles of anticardiolipin antibodies in sera from patients with SLE and infectious diseases. (1991) (27)
- High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells (2015) (27)
- Cow milk is not responsible for most gastrointestinal immune-like syndromes--evidence from a population-based study. (2005) (26)
- Antibodies binding to anionic phospholipids but not to oxidized low-density lipoprotein are associated with thrombosis in patients with systemic lupus erythematosus. (1996) (25)
- No association between vitamin D and β‐cell autoimmunity in Finnish and Estonian children (2014) (25)
- Whole-Genome Sequencing Identifies STAT4 as a Putative Susceptibility Gene in Classic Kaposi Sarcoma. (2015) (25)
- The association of antibodies to cardiolipin, β2‐glycoprotein I, prothrombin, and oxidized low‐density lipoprotein with thrombosis in 292 patients with familial and sporadic systemic lupus erythematosus (2004) (25)
- Variation in enterovirus receptor genes (2003) (24)
- Autoimmunity to glutamic acid decarboxylase in patients with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED) (2000) (24)
- Antibodies to β2-glycoprotein I and prothrombin in habitual abortion (1996) (23)
- Expression pattern of T-helper 17 cell signaling pathway and mucosal inflammation in celiac disease (2014) (23)
- omega-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk (2016) (22)
- Diabetes: Should we treat infection or inflammation to prevent T2DM? (2012) (22)
- Enterovirus infection and activation of human umbilical vein endothelial cells (2003) (22)
- Soluble Adhesion Molecules and Oral Antigen Feeding in Infants (1996) (22)
- Asthma and allergic symptoms and type 1 diabetes‐related autoantibodies in 2.5‐yr‐old children (2011) (22)
- Increased activation of GATA‐3, IL‐2 and IL‐5 of cord blood mononuclear cells in infants with IgE sensitization (2008) (21)
- Interleukin-17 Immunity in Pediatric Crohn Disease and Ulcerative Colitis (2013) (21)
- T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies. (2008) (21)
- Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals (2014) (21)
- Editorial Atherosclerosis in SLE and Hughes syndrome (1997) (21)
- Activation of T Cells in Preterm Infants with Respiratory Distress Syndrome (2009) (21)
- Aberrant regulation of interleukin‐12 receptor β2 chain on type 1 cytokine‐stimulated T lymphocytes in type 1 diabetes (2005) (21)
- Antibodies to Deamidated Gliadin Peptide in Diagnosis of Celiac Disease in Children (2015) (21)
- Using Novel Computed Tomography Analysis to Describe the Contribution and Distribution of Emphysema and Small Airways Disease in Chronic Obstructive Pulmonary Disease (2019) (21)
- Progression to type 1 diabetes and autoantibody positivity in relation to HLA‐risk genotypes in children participating in the ABIS study (2008) (21)
- Interferon‐γ Production in Antigen Specific T Cell Response: Quantitation of Specific mRNA and Secreted Protein (1997) (20)
- Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1 (2021) (20)
- Dietary insulin as an immunogen and tolerogen (2005) (20)
- Lactose inhibits regulatory T-cell-mediated suppression of effector T-cell interferon-γ and IL-17 production (2014) (19)
- Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial. (2017) (19)
- Is type 1 diabetes a disease of the gut immune system triggered by cow's milk insulin? (2005) (19)
- The association of CTLA‐4 and HLA class II autoimmune risk genotype with regulatory T cell marker expression in 5‐year‐old children (2006) (19)
- Coxsackievirus immunization delays onset of diabetes in non‐obese diabetic mice (2003) (19)
- Genetic and phenotypic diversity of echovirus 30 strains and pathogenesis of type 1 diabetes (2007) (19)
- Inflammatory response and IgE sensitization at early age (2013) (19)
- ANTICARDIOLIPIN ANTIBODIES IN GUILLAIN-BARRÉSYNDROME (1985) (19)
- Immune activation in the small intestine in patients with rheumatoid arthritis (2004) (19)
- Lipopolysaccharide-Induced Immune Responses in Relation to the TLR4(Asp299Gly) Gene Polymorphism (2008) (19)
- Does autoreactivity have a role in narcolepsy? (2014) (19)
- A functional complement system is required for normal T helper cell differentiation. (2011) (19)
- The role of the gut in β‐cell autoimmunity and type 1 diabetes: a hypothesis (2000) (18)
- Moisture damage in home associates with systemic inflammation in children. (2016) (18)
- Environmental factors in the aetiology of childhood diabetes. (1999) (18)
- Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case–control ancillary study (2020) (18)
- Dendritic Cells from Crohn’s Disease Patients Show Aberrant STAT1 and STAT3 Signaling (2013) (18)
- Anticardiolipin response and its association with infections in young and middle‐aged patients with cerebral infarction (1988) (18)
- Breastfeeding stimulates total and cow’s milk‐specific salivary IgA in infants (2009) (17)
- Few associations between high‐sensitivity C‐reactive protein and environmental factors in 4.5‐year‐old children (2012) (17)
- Diminished IFN‐γ response to diabetes‐associated autoantigens in children at diagnosis and during follow up of type 1 diabetes (2006) (17)
- Effect of HLA Genotype or CTLA‐4 Polymorphism on Cytokine Response in Healthy Children (2008) (17)
- Immunoglobulin A and immunoglobulin G antibodies against β‐lactoglobulin and gliadin at age 1 associate with immunoglobulin E sensitization at age 6 (2014) (17)
- Intestinal Cytokine mRNA Expression in Delayed-type Cow's Milk Allergy (2006) (16)
- Early human enterovirus infections in healthy Swedish children participating in the PRODIA pilot study (2012) (16)
- Two Insulin Gene Single Nucleotide Polymorphisms Associated with Type 1 Diabetes Risk in the Finnish and Swedish Populations (2007) (16)
- Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis. (2019) (16)
- Effect of maternal diet during lactation on development of bovine insulin-binding antibodies in children at risk for allergy. (2000) (16)
- Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial (2017) (16)
- Antibodies to beta 2-glycoprotein I and prothrombin in habitual abortion. (1996) (15)
- Altered expression of intestinal human leucocyte antigen D‐related and immune signalling molecules in juvenile idiopathic arthritis (2012) (15)
- Environmental causes: dietary causes. (2004) (15)
- Circulating Dendritic Cells, Farm Exposure and Asthma at Early Age (2016) (15)
- In Crohn's Disease, Anti-TNF-α Treatment Changes the Balance between Mucosal IL-17, FOXP3, and CD4 Cells (2012) (15)
- Human Leukocyte Antigen (DR1)-DQB1*0501 and (DR15)-DQB1*0602 Haplotypes Are Associated with Humoral Responses to Early Food Allergens in Children (2009) (15)
- Poor in vitro induction of FOXP3 and ICOS in type 1 cytokine environment activated T‐cells from children with type 1 diabetes (2008) (14)
- Environmental factors and primary prevention in type 1 diabetes. (2009) (14)
- Impaired intestinal tolerance in the absence of a functional complement system. (2013) (14)
- A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis (2020) (14)
- Effect of Lactobacillus rhamnosus GG on rBet v1 and rMal d1 specific IgA in the saliva of patients with birch pollen allergy. (2008) (12)
- Relation among mannose-binding lectin 2 genotype, beta-cell autoantibodies, and risk for type 1 diabetes in Finnish children. (2008) (12)
- MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling (2019) (12)
- Use of portable enrichment unit in rapid characterization of infantile intestinal enterobacterial microbiota (2009) (12)
- Altered regulation and expression of genes by BET family of proteins in COPD patients (2017) (12)
- Clinical significance of antibodies against oxidised low density lipoprotein in early RA. (1996) (12)
- Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function (2020) (12)
- Anticardiolipin Response in Kawasaki Disease (1990) (12)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Atherosclerosis in SLE and Hughes syndrome. (1997) (11)
- New means to monitor the effect of glucocorticoid therapy in children. (2010) (11)
- N-acetyltransferase-2 polymorphism, smoking and type 1 diabetic nephropathy. (1999) (11)
- Similar Antibody Levels in 3-Year-Old Children Vaccinated Against Measles, Mumps, and Rubella at the Age of 12 Months or 18 Months. (2016) (11)
- Antibodies against oxidised low-density lipoprotein in juvenile chronic arthritis. (1995) (11)
- Relation between T-cell responses to glutamate decarboxylase and coxsackievirus B4 in patients with insulin-dependent diabetes mellitus. (1999) (11)
- Homogenisation of milk has no effect on milk-specific antibodies in healthy adults (2003) (10)
- Cow milk proteins, autoimmunity and type 1 diabetes. (2009) (10)
- Use of vitamin D supplements during infancy in an international feeding trial (2013) (10)
- Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk (2021) (10)
- Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD (2019) (10)
- Lack of Functional Similarity Between Complement Factor H and Anticardiolipin Cofactor, β2‐Glycoprotein I (Apolipoprotein H) (1995) (10)
- Expansion of CD4+CD25+FOXP3+ regulatory T cells in infants of mothers with type 1 diabetes (2012) (9)
- Food and drug reactions and anaphylaxis Transforming growth factor-β1 in mothers' colostrum and immune responses to cows' milk proteins in infants with cows' milk allergy (1999) (9)
- Induction of Interferon-γ and IL-4 Production by Mitogen and Specific Antigens in Peripheral Blood Lymphocytes of Type 1 Diabetes Patients (2001) (9)
- Tissue Infiltrating LTi—Like Group 3 Innate Lymphoid Cells and T Follicular Helper Cells in Graves' and Hashimoto's Thyroiditis (2020) (9)
- Increased peripheral blood CD4+ T cell responses to deamidated but not to native gliadin in children with coeliac disease (2012) (9)
- GAD reactive lymphocytes from patients with insulin-dependent diabetes mellitus express a gut-specific homing receptor alpha4beta7 integrin (1997) (9)
- Reduced CCR4, interleukin‐13 and GATA‐3 up‐regulation in response to type 2 cytokines of cord blood T lymphocytes in infants at genetic risk of type 1 diabetes (2007) (9)
- Intestinal Immunity and Type 1 Diabetes (2004) (9)
- Immunologic and hematologic properties of antibodies to prothrombin and plasminogen in a mouse model (2001) (9)
- Antiphospholipid antibodies and thrombosis in systemic lupus erythematosus: comparison of three lupus anticoagulant assays and anticardiolipin ELISA in 188 patients (1992) (8)
- Ultrasensitive DNA Immune Repertoire Sequencing Using Unique Molecular Identifiers. (2020) (8)
- LFRET, a novel rapid assay for anti-tissue transglutaminase antibody detection (2019) (8)
- [Narcolepsy as an autoimmune disease]. (2015) (8)
- No evidence of the role of early chemical exposure in the development of β-cell autoimmunity (2018) (8)
- Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells (2018) (7)
- Effect of HLA DQ2, dietary exposure and coeliac disease on the development of antibody response to gliadin in children (2006) (7)
- Impaired Differentiation of Chronic Obstructive Pulmonary Disease Bronchial Epithelial Cells Grown on Bronchial Scaffolds (2021) (7)
- Serum antibodies to oxidised low-density lipoprotein (1994) (7)
- Diminished IFN-gamma response to diabetes-associated autoantigens in children at diagnosis and during follow up of type 1 diabetes. (2006) (7)
- Serum fatty acids and risk of developing islet autoimmunity: A nested case–control study within the TRIGR birth cohort (2020) (7)
- Exposure to sewage water and the development of allergic manifestations in Finnish children (2019) (6)
- Infection, anticardiolipin and thrombosis. (1987) (6)
- Effect of Early Feeding on Intestinal Permeability and Inflammation Markers in Infants with Genetic Susceptibility to Type 1 Diabetes: A Randomized Clinical Trial. (2021) (6)
- Anti-insulin Activity in IgG-fractions from Children with Newly-diagnosed Type 1 Diabetes and Negative for Insulin Autoantibodies (2004) (6)
- Correction: The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes (vol 17, pg 260, 2015) (2016) (6)
- Monocyte‐derived dendritic cells from Crohn's disease patients exhibit decreased ability to activate T helper type 17 responses in memory cells (2014) (5)
- Anti-Prothrombin Antibodies in Thrombosis and Atherosclerosis (2001) (5)
- Dynamics of IFN-ß responses during respiratory viral infection: insights for therapeutic strategies (2019) (5)
- False-positive seroreactions for syphilis as a harbinger of disease revisited. (1989) (5)
- Consumption of Galactooligosaccharides together with Probiotics Stimulates the In Vitro Peripheral Blood Mononuclear Cell Proliferation and IFNγ Production in Healthy Men (2011) (4)
- Serum immune-activation potency and response to anti-TNF-α therapy in Crohn's disease. (2010) (4)
- Accelerated Atherosclerosis in Antiphospholipid Syndrome (2000) (4)
- Development of Immune Response to Orally Administered Cow Milk Protein in Young Children (1996) (4)
- Antiphospholipid antibodies and thrombosis in systemic lupus erythematosus: comparison of three lupus anticoagulant assays and anticardiolipin ELISA in 188 patients. (1992) (4)
- Using DPM CT analysis to assess the contribution of small airways disease in COPD (2018) (4)
- No evidence for activation of TH1 or TH17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D (2008) (3)
- Using Novel CT Analysis to Describe the Contribution and Distribution of Emphysema and Small Airways Disease in COPD. (2019) (3)
- Genetic variations in A 20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus (2019) (3)
- Intra-articular corticoid injection induces circulating glucocorticoid bioactivity and systemic immune activation in juvenile idiopathic arthritis (2011) (3)
- No evidence of autoimmunity to human OX1 or OX2 orexin receptors in Pandemrix-vaccinated narcoleptic children (2020) (3)
- Induction of Diabetes‐Related Autoantibodies below Cutoff for “Positivity” in Young Nondiabetic Children (2003) (3)
- Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life (2021) (2)
- ENHANCED T-CELL REACTIVITY TO INSULIN PEPTIDE A1-12 IN CHILDREN WITH RECENTLY DIAGNOSED TYPE 1 DIABETES OR DIABETES ASSOCIATED AUTOANTIBODIES (2005) (2)
- Genetics of vaccination-related narcolepsy (2017) (2)
- Breastfeeding and circulating immunological markers during the first 3 years of life: the DIABIMMUNE study (2021) (2)
- Erratum: HLA-DPB1 and HLA class i confer risk of and protection from narcolepsy (American Journal of Human Genetics (2015) 96 (136-146)) (2015) (2)
- Genetics Association and Epigenetic Changes in COPD (2018) (2)
- Correction: Altered regulation and expression of genes by BET family of proteins in COPD patients (2017) (1)
- WEANING TO A HYDROLYZED FORMULA IN INFANCY DECREASES THE CUMULATIVE INCIDENCE OF BETA-CELL AUTOIMMUNITY IN YOUNG HIGH-RISK CHILDREN (2005) (1)
- Breast-milk microbes and risk of asthma by 6 years of age (2018) (1)
- Antibodies to phospholipid-binding proteins and occurence of clinical manifestations in patients with systemic lupus erythematosus (1996) (1)
- DIABETIC STUDIES The Review of Chapter II . 1 Gut Microbiota and Type 1 Diabetes (2013) (1)
- Atherosclerosis in SLE and in Hughes syndrome (editorial) (1997) (1)
- O10.1. CORRELATIONS BETWEEN INSULIN RESISTANCE AND PERIPHERAL IMMUNITY IN FIRST-EPISODE PSYCHOSIS – A GENE EXPRESSION STUDY (2019) (0)
- Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines Vaarala, Outi (0)
- SAT0251 Selective glucocorticoid receptor modulator shows potent anti-inflammatory effect with improved metabolic profile in a phase i study supported by in vitro data (2018) (0)
- 257 Low Proportions of Peripheral Blood TCRãä-Cells in Newborn Infants (2004) (0)
- Long-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients (2017) (0)
- The protein composition and the preparation and use thereof and products containing same and the preparation thereof (1997) (0)
- Immunology of Atherosclerosis (2001) (0)
- Antibodies against oxidized LDL and gemfibrozil treatment (1994) (0)
- TheDynamics of theHuman InfantGutMicrobiome in Development and in Progression toward Type 1 Diabetes Graphical (2015) (0)
- Clinical significance of antibodies to oxidized LDL in a prospective study of early rheumatoid arthritis (1996) (0)
- ATOPIC SYMPTOMS AND BETA-CELL AUTOIMMUNITY DURING THE FIRST TWO YEARS OF LIFE (2005) (0)
- Candidate Molecules that Alter the Abnormal Mucosal Immune System in Human Type 1 Diabetes (2007) (0)
- Relation between cytokine production and age in patients with type 1 diabetes (2000) (0)
- Non-class II HLA gene associated with type 1 diabetes mellitus maps to the 240 kilobase region near HLA-B (2000) (0)
- Serum IgA and IgG antibodies to wheat gliadin and milk beta-lactoglobulin in early infancy predict atopic sensitisation at school age (2013) (0)
- Down regulation of anti-inflammatory cytokines in ileal mucosa associates with active disease in juvenile idiopathic arthritis (2011) (0)
- Clinical Study In Crohn ’ s Disease , Anti-TNF-α Treatment Changes the Balance betweenMucosal IL-17 , FOXP 3 , and CD 4 Cells (2014) (0)
- COPD phenotypes revealed by the integrated sputum microbiome and proteome analysis in COPDMAP cohort (2019) (0)
- Quantification of intestinal bacterial groups shows differences between pediatric patients with inflammatory bowel disease and healthy children (2011) (0)
- Insulin treatment during pregnancy induces insulin-reactive CD4+CD25+FOXP3+regulatory T cells in the infant (2010) (0)
- Increased fecal calprotectin at age 2 months associates with early colonisation pattern and predicts atopic dermatitis and asthma by the age of 6 years (2014) (0)
- Effects of early life farm exposure on phenotype and functional properties of dendritic cells (2013) (0)
- Coxsackievirus up-regulates IL-17 immunity in human type 1 diabetes (2013) (0)
- Subejct Index Vol. 96, 2009 (2009) (0)
- Combination of probiotics, and use of this (2002) (0)
- COPD_A_211619 2611..2624 (2019) (0)
- T17 gene asthma signature characterized by sputum neutrophilia and regular use of antibiotics (2017) (0)
- Long-term effects of weaning habits: type-1 diabetes. (2005) (0)
- [The role of the intestinal immune system in the etiology of type 1 diabetes]. (2000) (0)
- Asthma and lower airway disease v-3 fatty acids contribute to the asthma-protective effect of unprocessed cow’s milk (2016) (0)
- Complement Component C3 is Required for Normal T Helper Cell Immunity (2013) (0)
- Th1/Th2 (PP-015) (2010) (0)
- IL-6 Trans-Signaling Definesa New Asthma Phenotype Associated with Frequent Exacerbations, Increased Airway Inflammation and Impaired Epithelial Integrity (2018) (0)
- SLE as a Model of Autoimmune Atherosclerosis (2001) (0)
- POOR IN VITRO INDUCTION OF Treg CELLS IN TYPE 1 CYTOKINE ENVIRONMENT IN CHILDREN WITH RECENTLY DIAGNOSED TYPE 1 DIABETES (2005) (0)
- Contents Vol. 96, 2009 (2009) (0)
- 91 Can Postnatal Supplementation with Probiotics Reduce the Risk for Allergic Disease in Infancy|[quest]| (2010) (0)
- Regulatory T cells in children with type 1 diabetes (2008) (0)
- SHORT DURATION OF BREASTFEEDING AS A RISK-FACTOR FOR BETA-CELL AUTOANTIBODIES IN FIVE-YEAR-OLD HEALTHY CHILDREN (2005) (0)
- S95 Role of ifn&bgr; in modulating innate immunity of primary bronchial epithelial cells (PBECs) during respiratory infection (2018) (0)
- Long-Term Effects of Weaning Habits : Type-1 Diabetes 177 (2005) (0)
- [The new face of phospholipid antibodies]. (1993) (0)
- S96 IFN-β dynamics during respiratory viral infection of macrophages: insights for therapeutic strategies (2018) (0)
- Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD (2022) (0)
- Chapter 7 – The Developing Gastrointestinal Tract in Relation to Autoimmune Disease, Allergy, and Atopy (2012) (0)
- Dynamics of IFN-β responses during respiratory viral infection: insights for therapeutic strategies (2019) (0)
- HLA haplotypes and insulin gene VNTR polymorphism in relation to markers of beta-cell autoimmunity in children from the general population (2006) (0)
- Hydrolyzed infant formula and early β-cell autoimmunity (2015) (0)
- Heterogeneity in diabetes-associated autoantibodies and susceptibility to Type 1 diabetes: lessons for disease prevention (2015) (0)
- A method of removing bovine insulin (1998) (0)
- VII International "Onnela" Workshop: Gut Immune System and Type 1 Diabetes Mellitus (2000) (0)
- The effect of transforming growth factor-beta 1 and immunoglobulin A in breast milk and duration of breast feeding on atopy and atopic dermatitis (2013) (0)
- Low-grade inflammation at early age decreases the risk of IgE-sensitisation (2014) (0)
- Poster #S58 SERUM LEVELS OF INNATE IMMUNE RESPONSE MARKERS CCL22, CXCL1 AND APOLIPOPROTEIN A1 ALTERED IN FIRST-EPISODE PSYCHOSIS ASSOCIATE WITH WHITE MATTER VOLUME AND INTEGRITY (2014) (0)
- Environmental pollutants and the risk of type 1 diabetes (2015) (0)
- Reduced expression of CCR4 on cord blood T lymphocytes in neonates at genetic risk of type 1 diabetes (2012) (0)
- O20 NAT2 polymorphism, smoking and type 1 diabetic nephropathy (1999) (0)
- Probiotics and innate immune response in infants (2014) (0)
- M72 GENETICS OF VACCINATION RELATED NARCOLEPSY (2019) (0)
- Maternal type 1 diabetes modifies immunization to dietary insulin in infancy (2000) (0)
- Higher circulating EGF levels associate with a decreased risk of IgE sensitization in young children (2021) (0)
- Next generation glucocorticoid receptor modulators (2018) (0)
- A process for the production of protein material (1999) (0)
- Infant feeding, gut permeability, and gut inflammation markers. (2023) (0)
- Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells (2018) (0)
- Respiratory epithelial cells mediate distinct inflammatory responses to different bacterial pathogens (2013) (0)
- Delayed activation of CD8+T-cells in preterm infants to mothers with prom (2003) (0)
- 256 Activation of Circulating CD4+ T-Cells in Preterm Infants with RDS (2004) (0)
- T regulatory cell expression profile distinguishes children with persisting cow's milk allergy from children tolerating cow's milk (2014) (0)
- Impaired intestinal tolerance in the absence of complement C3 (2012) (0)
- Cellular immune response to cow mils B-lactoglubin in patients with newly diagnosed insulin-dependent diabetes mellitus (1996) (0)
- CAN POSTNATAL SUPPLEMENTATION WITH PROBIOTICS REDUCE THE RISK FOR ALLERGIC DISEASE IN INFANCY (2010) (0)
- 4:30 PM INFLAMMATORY RESPONSE IN FIRST-EPISODE PSYCHOSIS (2014) (0)
- Method for detecting autoimmune diseases (2008) (0)
- Delayed activation of CD8-positive T-cells in preterm infants to mothers with premature rupture of membranes (PROM) (2003) (0)
- Breast-milk microbiome and risk of asthma by 6 years of age (2017) (0)
- Feeding cow milk induces antibodies to insulin in children - a link between cow milk and IDDM (1998) (0)
- Probiotics modulate monocytes in infants at genetic risk of type 1 diabetes (2013) (0)
- Associations Between Serum Fatty Acids and Immunological Markers in Children Developing Islet Autoimmunity—The TRIGR Nested Case–Control Study (2022) (0)
- LEVELS OF HLA-G EXPRESSION DEFINE THE TOLEROGENIC ACTIVITY OF DC-10 (2014) (0)
- RISK GENE PROFILE IN FINNISH PANDEMRIX ASSOCIATED NARCOLEPSY (2014) (0)
- Genetics Association and Epigenetic Changes in COPD Genetics Association and Epigenetic Changes in COPD (2018) (0)
- Cardiolipin-binding antibodies in patients with infections and autoimmune disorders (1991) (0)
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