Owen Witte

Q: What Schools Are Affiliated With Owen Witte

Owen Witte is affiliated with the following schools: California Institute of Technology, University of Tokyo, Medical University of South Carolina, University of California, Los Angeles, Umeå University, Stanford University, Cornell University, Gifu Pharmaceutical University, University of Padua, University of Washington, University of California, San Francisco

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Owen Witte

Biology

#1287

World Rank

#2181

Historical Rank

#654

USA Rank

Microbiology

#112

World Rank

#135

Historical Rank

#48

USA Rank

biology Degrees

Owen Witte

Philosophy

#3494

World Rank

#5636

Historical Rank

#1109

USA Rank

Logic

#1193

World Rank

#1878

Historical Rank

#375

USA Rank

philosophy Degrees

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Biology
Philosophy

Owen Witte's Degrees

Masters Medicine Stanford University
PhD Microbiology Stanford University

Why Is Owen Witte Influential?

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According to Wikipedia, Owen Witte is an American physician-scientist at the University of California, Los Angeles. He is a distinguished professor of microbiology, immunology and molecular genetics in the David Geffen School of Medicine at UCLA, founding director of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and the UC Regents’ David Saxon Presidential Chair in developmental immunology . Witte is also a Howard Hughes Medical Institute investigator and a member of the President's Cancer Panel . He also served on the Life Sciences jury for the Infosys Prize in 2013.

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Owen Witte's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. (1990) (1397)
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia (1993) (1285)
An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity (1984) (879)
The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. (1986) (839)
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. (1988) (729)
Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. (1998) (697)
Long-term culture of B lymphocytes and their precursors from murine bone marrow. (1982) (598)
Identification of a Cell of Origin for Human Prostate Cancer (2010) (544)
The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. (1999) (526)
Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL. (1990) (519)
Differential expression of myc family genes during murine development (1986) (513)
Stomatal Size in Fossil Plants : Evidence for Polyploidy in Majority of Angiosperms (503)
Steel locus defines new multipotent growth factor (1990) (501)
Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics (2005) (458)
Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases (1996) (452)
Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B‐cell receptor activation (1998) (445)
Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine (1980) (438)
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis. (2005) (438)
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice (1997) (427)
Dominant negative MYC blocks transformation by ABL oncogenes (1992) (418)
Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA (1980) (413)
Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study. (2018) (401)
Isolation and functional characterization of murine prostate stem cells (2007) (401)
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (2018) (398)
BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias (1991) (397)
In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome. (1987) (380)
The BCR-ABL story: bench to bedside and back. (2004) (377)
Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia (1996) (366)
Leukemia and the disruption of normal hematopoiesis (1991) (360)
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner (1991) (358)
Impaired expansion of mouse B cell progenitors lacking Btk. (1995) (340)
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics (2008) (333)
Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL. (1987) (331)
Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation (2006) (320)
Lysophosphatidylcholine as a Ligand for the Immunoregulatory Receptor G2A (2001) (316)
Regulation of Btk function by a major autophosphorylation site within the SH3 domain. (1996) (316)
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. (1999) (315)
Regional gene therapy with a BMP‐2‐producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents (1998) (298)
The nuclear tyrosine kinase c-abl negatively regulates cell growth (1994) (292)
Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene (1995) (288)
Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene (1995) (286)
Basal epithelial stem cells are efficient targets for prostate cancer initiation (2010) (271)
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. (2010) (267)
DNA-encoded antibody libraries: a unified platform for multiplexed cell sorting and detection of genes and proteins. (2007) (267)
The BCR gene encodes a novel serine/threonine kinase activity within a single exon (1991) (266)
Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production (1998) (263)
Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration. (1985) (258)
Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. (1994) (258)
Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL). (1988) (258)
Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products (1985) (256)
Bcl-2-independent Bcr–Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL (1998) (247)
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. (2016) (247)
Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4* (2001) (229)
Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. (1994) (229)
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy. (2016) (229)
Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking (1994) (220)
Migration to Apoptotic “Find-me” Signals Is Mediated via the Phagocyte Receptor G2A* (2008) (219)
Xid-like phenotypes: a B cell signalosome takes shape. (2000) (217)
Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblast and lymphoid cells. (1978) (215)
Murine B cell lymphopoiesis in long term culture. (1984) (214)
The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. (2000) (211)
Differential complementation of Bcr-Abl point mutants with c-Myc. (1994) (205)
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells (2009) (205)
Self‐Renewal and Multilineage Differentiation In Vitro from Murine Prostate Stem Cells (2007) (201)
In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme (2003) (201)
A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells (1987) (195)
Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases (1997) (194)
Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain. (1995) (193)
Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. (2001) (192)
IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases (1994) (191)
Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. (2007) (191)
Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model. (2009) (191)
Btk function in B cell development and response. (1998) (190)
Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts (2001) (188)
Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage (2018) (187)
Redundant and Opposing Functions of Two Tyrosine Kinases, Btk and Lyn, in Mast Cell Activation1 (2000) (186)
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. (2006) (185)
Molecular imaging of lymphoid organs and immune activation using positron emission tomography with a new 18F-labeled 2′-deoxycytidine analog (2008) (184)
Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma (2014) (183)
Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. (2005) (182)
Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro. (1992) (180)
Abelson murine leukemia virus-induced tumors elicit antibodies against a host cell protein, P50 (1980) (178)
T cell chemotaxis to lysophosphatidylcholine through the G2A receptor (2003) (178)
Stem cells in prostate cancer initiation and progression. (2007) (178)
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc (1989) (177)
A basal stem cell signature identifies aggressive prostate cancer phenotypes (2015) (176)
Isolation, cultivation and characterization of adult murine prostate stem cells (2010) (173)
Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A. (2005) (169)
Relationship of retrovirus polyprotein cleavages to virion maturation studied with temperature-sensitive murine leukemia virus mutants (1978) (165)
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer (2016) (164)
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor (2006) (163)
Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide. (1981) (163)
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells. (2011) (161)
Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines. (1995) (157)
A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. (1992) (156)
High frequency of aberrant expression of moloney murine leukemia virus in clonal infections (1978) (156)
PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization (2001) (154)
Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells (1989) (152)
Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties (1985) (152)
The viral and cellular forms of the Abelson (abl) oncogene. (1988) (152)
Stem‐Like Epithelial Cells Are Concentrated in the Distal End of the Fallopian Tube: A Site for Injury and Serous Cancer Initiation (2012) (150)
Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice. (1993) (149)
Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression (2012) (148)
Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells (2013) (147)
Human Prostate Sphere-Forming Cells Represent a Subset of Basal Epithelial Cells Capable of Glandular Regeneration in Vivo (2009) (146)
The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts. (1987) (146)
Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies (2008) (146)
Quantitative imaging of the T cell antitumor response by positron-emission tomography (2003) (144)
Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo (2014) (142)
Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate. (2000) (141)
A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. (1998) (141)
The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function. (1995) (140)
SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence (1993) (139)
Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. (1990) (138)
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. (1991) (138)
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. (2015) (137)
p53 dependent growth suppression by the c-Abl nuclear tyrosine kinase. (1995) (136)
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias. (1998) (135)
Cellular maturation of oncornavirus glycoproteins: topological arrangement of precursor and product forms in cellular membranes. (1977) (128)
A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product (1979) (122)
Brief report: a point mutation in the SH2 domain of Bruton's tyrosine kinase in atypical X-linked agammaglobulinemia. (1994) (121)
Protein binding and signaling properties of RIN1 suggest a unique effector function. (1997) (120)
Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome. (1986) (119)
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy. (2013) (119)
Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors. (1997) (119)
A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity. (1980) (117)
Regulation of Btk by Src family tyrosine kinases (1996) (113)
Btk dosage determines sensitivity to B cell antigen receptor cross-linking. (1997) (111)
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets (2013) (111)
Vascular Abnormalities in Mice Deficient for the G Protein-Coupled Receptor GPR4 That Functions as a pH Sensor (2006) (110)
Propagation of human blastic myeloid leukemias in the SCID mouse. (1992) (109)
Role of Bruton's tyrosine kinase in immunodeficiency. (1994) (107)
Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling. (2012) (106)
Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway (2011) (106)
Lysophosphatidylcholine as a ligand for immunoregulation. (2002) (106)
Bruton's Tyrosine Kinase is a Key Regulator in B‐Cell Development (1994) (105)
Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking. (2000) (104)
Identification of CD166 as a Surface Marker for Enriching Prostate Stem/Progenitor and Cancer Initiating Cells (2012) (104)
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. (2008) (102)
An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells. (2009) (102)
Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression (2002) (99)
The Dimerization Property of Glutathione S-Transferase Partially Reactivates Bcr-Abl Lacking the Oligomerization Domain* (1996) (99)
Preparation of syngeneic tumor regressor serum reactive with the unique determinants of the Abelson murine leukemia virus-encoded P120 protein at the cell surface (1979) (98)
DNA methylation landscapes in advanced prostate cancer (2020) (98)
Immuno-PET of Murine T Cell Reconstitution Postadoptive Stem Cell Transplantation Using Anti-CD4 and Anti-CD8 Cys-Diabodies (2015) (97)
Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene. (1991) (94)
Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity (1984) (94)
Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay (2016) (92)
Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation (1980) (92)
Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice. (1995) (92)
Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways (1998) (89)
T cell antigen discovery via trogocytosis (2019) (89)
Differentiation of cloned populations of immature B cells after transformation with abelson murine leukemia virus (1983) (89)
Purification and direct transformation of epithelial progenitor cells from primary human prostate (2011) (88)
Structural characteristics of some murine RNA tumor viruses studied by lactoperoxidase iodination. (1973) (87)
Long-term culture system for selective growth of human B-cell progenitors. (1995) (86)
Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells. (2004) (86)
Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1. (1997) (86)
Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. (2009) (85)
Invasive prostate carcinoma driven by c-Src and androgen receptor synergy. (2011) (85)
Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA) (1994) (84)
Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells. (2009) (84)
Differential transformation capacity of Src family kinases during the initiation of prostate cancer (2011) (83)
Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome (2016) (82)
Lysophosphatidylcholine-induced surface redistribution regulates signaling of the murine G protein-coupled receptor G2A. (2005) (82)
Signaling by ABL oncogenes through cyclin D1. (1995) (82)
Lethal effect of the abelson murine leukemia virus transforming gene product (1981) (81)
Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures (1988) (80)
Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes (2001) (79)
Constitutive membrane association potentiates activation of Bruton tyrosine kinase (1997) (79)
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress (2012) (79)
Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis (2007) (78)
Visualization of a primary anti-tumor immune response by positron emission tomography. (2005) (77)
Structure of the murine leukemia virus envelope glycoprotein precursor (1979) (77)
Consequences of BCR‐ABL Expression within the Hematopoietic Stem Cell in Chronic Myeloid Leukemia (2000) (76)
Modeling Philadelphia chromosome positive leukemias (2001) (76)
Abelson murine leukemia virus mutants with alterations in the virus-specific P120 molecule (1980) (76)
Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling (2012) (75)
Primitive origins of prostate cancer: In vivo evidence for prostate‐regenerating cells and prostate cancer‐initiating cells (2010) (75)
Requirement for deoxycytidine kinase in T and B lymphocyte development (2009) (75)
Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations. (2004) (75)
Synergism of v-myc and v-Ha-ras in the in vitro neoplastic progression of murine lymphoid cells (1986) (75)
Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer (2018) (74)
In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog (1982) (74)
Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. (2019) (73)
Progression of the transformed phenotype in clonal lines of Abelson virus-infected lymphocytes (1983) (72)
Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics (2007) (72)
A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction (1992) (72)
Normal Immune Development and Glucocorticoid-Induced Thymocyte Apoptosis in Mice Deficient for the T-Cell Death-Associated Gene 8 Receptor (2006) (72)
Genome structure of Abelson murine leukemia virus variants: proviruses in fibroblasts and lymphoid cells (1981) (71)
Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia. (2007) (71)
Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses (2010) (70)
Abelson virus-infected cells can exhibit restricted in vitro growth and low oncogenic potential (1981) (70)
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells (2001) (70)
Mechanism of formation of pseudotypes between vesicular stomatitis virus and murine leukemia virus (1977) (69)
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance (2020) (68)
Differentiation of human CD34+CD38- cord blood stem cells into B cell progenitors in vitro. (1997) (68)
FOXA2 is a Sensitive and Specific marker for Small Cell Neuroendocrine Carcinoma of the Prostate (2017) (68)
Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells. (2011) (67)
Photothermal nanoblade for large cargo delivery into mammalian cells (2011) (66)
Clinical Targeting of Mutated and Wild-Type Protein Tyrosine Kinases in Cancer (2014) (66)
In vitro reconstitution of human B-cell ontogeny: from CD34(+) multipotent progenitors to Ig-secreting cells. (1998) (65)
Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene. (2004) (64)
Distinctive growth requirements and gene expression patterns distinguish progenitor B cells from pre-B cells (1993) (63)
Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoter (2001) (63)
[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity (2016) (62)
Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement. (2000) (62)
Transformation of Immature Lymphoid Cells by Abelson Murine Leukemia Virus (1979) (61)
A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers. (2018) (60)
Activation of the abl oncogene in murine and human leukemias. (1985) (59)
Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain (2008) (59)
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood (2019) (57)
Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOS (1995) (56)
Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium (2010) (55)
Complementary Roles for CD19 and Bruton’s Tyrosine Kinase in B Lymphocyte Signal Transduction1 (2002) (55)
Oncogenic activation of c-ABL by mutation within its last exon (1993) (54)
Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography (2009) (54)
Reduced Dosage of Bruton’s Tyrosine Kinase Uncouples B Cell Hyperresponsiveness from Autoimmunity in lyn−/− Mice1 (2003) (54)
Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy. (2013) (54)
Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer. (2004) (51)
Cell context-specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors. (2003) (51)
Site-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality (1983) (51)
Molecular pathogenesis of Ph-positive leukemias. (1989) (51)
Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells. (2000) (50)
Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases. (1997) (50)
In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies. (1999) (50)
Novel PET Probes Specific for Deoxycytidine Kinase (2010) (49)
Role of the BCR-ABL oncogene in human leukemia: fifteenth Richard and Hinda Rosenthal Foundation Award Lecture. (1993) (49)
Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer (2019) (49)
Prostate stem cells and prostate cancer. (2005) (49)
Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes. (1978) (48)
Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene. (2002) (48)
Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039)) (2018) (48)
Functional screen identifies kinases driving prostate cancer visceral and bone metastasis (2015) (47)
Estrogen and progesterone together expand murine endometrial epithelial progenitor cells (2013) (47)
MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer (2019) (47)
The AML1/Evi-1 fusion protein in the t(3;21) translocation exhibits transforming activity on Rat1 fibroblasts with dependence on the Evi-1 sequence. (1995) (46)
Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules (2018) (46)
Interleukin-6 and Oncostatin-M Synergize with the PI3K/AKT Pathway to Promote Aggressive Prostate Malignancy in Mouse and Human Tissues (2013) (45)
Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. (2010) (45)
Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function. (1990) (45)
Immune response to Philadelphia chromosome-positive acute lymphoblastic leukemia induced by expression of CD80, interleukin 2, and granulocyte-macrophage colony-stimulating factor. (1998) (45)
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (2018) (44)
Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. (2013) (44)
Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen (2008) (44)
BCR/ABL inhibition by an escort/phosphatase fusion protein. (2000) (43)
Integrated microfluidic devices for combinatorial cell-based assays (2009) (43)
Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene (2013) (43)
Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules (1986) (43)
Alternative pathways to prostate carcinoma activate prostate stem cell antigen expression. (2001) (43)
A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase. (2000) (42)
Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway (2010) (41)
Lymphoid bone marrow cultures can reconstitute heterogeneous B and T cell-dependent responses in severe combined immunodeficient mice. (1986) (40)
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. (2019) (39)
Long-term culture of murine bone marrow precursors of B lymphocytes. (1987) (39)
In vitro development of B lymphocytes from long-term cultured precursor cells. (1986) (38)
Genetic analysis of tyrosine kinase function in B cell development. (1996) (38)
Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer (2016) (38)
Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation. (1987) (38)
Long-term cultures of murine fetal liver retain very early B lymphoid phenotype (1984) (38)
Functional analysis of the AUG- and CUG-initiated forms of the c-Myc protein. (1994) (38)
Advances in PET Detection of the Antitumor T Cell Response. (2016) (38)
Monoclonal antibody to the amino-terminal L sequence of murine leukemia virus glycosylated gag polyproteins demonstrates their unusual orientation in the cell membrane (1986) (38)
Deletion of PSCA increases metastasis of TRAMP‐Induced prostate tumors without altering primary tumor formation (2008) (37)
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal (2011) (37)
PET probes for distinct metabolic pathways have different cell specificities during immune responses in mice. (2010) (36)
Differential regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros (2013) (35)
Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells (2015) (34)
Oncornavirus budding: kinetics of formation and utilization of viral membrane glycoprotein. (1976) (33)
Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients. (1986) (33)
Bruton's tyrosine kinase is required for signaling the CD79b-mediated pro-B to pre-B cell transition. (2001) (33)
Baculovirus expression of functional P210 BCR-ABL oncogene product. (1989) (33)
Does the microenvironment influence the cell types of origin for prostate cancer? (2013) (33)
Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer. (2012) (32)
A recombinant murine retrovirus expressing v-rel is cytopathic. (1988) (32)
Hyperexpression of interleukin-7 is not necessary or sufficient for transformation of a pre-B lymphoid cell line (1991) (32)
Biosynthesis of murine terminal deoxynucleotidyltransferase. (1980) (31)
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre–B ALL (2017) (31)
Polypeptides of Moloney sarcoma-leukemia virions: their resolution and incorporation into extracellular virions. (1974) (31)
Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells (1986) (31)
Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers (2020) (30)
Phosphorylation of the Abelson murine leukemia virus transforming protein (1981) (30)
Quantifying Biomass Changes of Single CD8+ T Cells during Antigen Specific Cytotoxicity (2013) (30)
Low Levels of Circulating Estrogen Sensitize PTEN-Null Endometrial Tumors to PARP Inhibition In Vivo (2013) (30)
Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes. (2008) (30)
Recognition of multiple substrate motifs by the c-ABL protein tyrosine kinase. (2002) (29)
Visualizing cancer and immune cell function with metabolic positron emission tomography. (2010) (29)
Long-term cultured B lymphocytes and their precursors reconstitute the B-lymphocyte lineage in vivo. (1984) (28)
The complexity of virus--cell interactions in Abelson virus infection of lymphoid and other hematopoietic cells. (1985) (28)
Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. (2015) (28)
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment. (2012) (28)
A Btk transgene restores the antiviral TI‐2 antibody responses of xid mice in a dose‐dependent fashion (1999) (28)
Target Antigens for Prostate Cancer Immunotherapy (2004) (28)
Long-term murine hemopoietic cultures as model systems for analysis of B lymphocyte differentiation. (1987) (27)
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. (2014) (27)
Kir, a novel Ras-family G-protein, induces invasive pseudohyphal growth in Saccharomyces cerevisiae. (1995) (26)
Pre-B cells in κ-transgenic mice (1985) (26)
RNA Dysregulation: An Expanding Source of Cancer Immunotherapy Targets. (2021) (25)
The role of Bcr-Abl in chronic myeloid leukemia and stem cell biology. (2001) (25)
P185BCR-ABL in two patients with late appearing Philadelphia chromosome-positive acute nonlymphocytic leukemia. (1989) (25)
Analysis of human c-Abl tyrosine kinase activity and regulation in S. pombe. (1996) (24)
BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets (1993) (24)
Induction of In Vivo Antipolysaccharide Immunoglobulin Responses to Intact Streptococcus pneumoniae Is More Heavily Dependent on Btk-Mediated B-Cell Receptor Signaling than Antiprotein Responses (2006) (24)
Epithelial stem cells of the prostate and their role in cancer progression. (2008) (24)
The 5' noncoding region of the human leukemia-associated oncogene BCR/ABL is a potent inhibitor of in vitro translation (1989) (24)
Non‐invasive imaging of adaptive immunity using positron emission tomography (2008) (23)
Deoxycytidine Kinase Augments ATM-Mediated DNA Repair and Contributes to Radiation Resistance (2014) (23)
Targeting RET Kinase in Neuroendocrine Prostate Cancer (2019) (23)
Deletion of the ABL SH3 domain reactivates de‐oligomerized BCR‐ABL for growth factor independence (1996) (23)
GCKR links the Bcr-Abl oncogene and Ras to the stress-activated protein kinase pathway. (1999) (20)
GCKR Links the Bcr-Abl Oncogene and Ras to the Stress-Activated Protein Kinase Pathway (1999) (20)
Epithelial uptake of [18F]1-(2'-deoxy-2'-arabinofuranosyl) cytosine indicates intestinal inflammation in mice. (2010) (19)
Lift NIH restrictions on chimera research. (2015) (19)
A membrane-associated, carbohydrate-modified form of the v-abl protein that cannot be phosphorylated in vivo or in vitro (1984) (19)
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver (2014) (19)
Molecular and cellular biology of Abelson virus transformation. (1983) (18)
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. 1993. (2012) (18)
Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination. (1994) (17)
Targeting leukemia stem cells (2010) (17)
A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation. (2004) (17)
IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease (2003) (17)
En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase. (1993) (17)
Immature B-cell progenitors survive oncogenic stress and efficiently initiate Ph+ B-acute lymphoblastic leukemia. (2010) (17)
Mutational analysis of the SH2-kinase linker region of Bruton's tyrosine kinase defines alternative modes of regulation for cytoplasmic tyrosine kinase families. (2006) (17)
ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1 (2010) (16)
Structural characterization of the BCR gene product. (1989) (16)
A trans-acting protein kinase identified in cells transformed by Abelson murine leukemia virus. (1980) (16)
Clinical and genomic characterization of metastatic small cell/neuroendocrine prostate cancer (SCNC) and intermediate atypical prostate cancer (IAC): Results from the SU2C/PCF/AACRWest Coast Prostate Cancer Dream Team (WCDT). (2016) (16)
A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes (2019) (16)
A Two-Step Toward Personalized Therapies for Prostate Cancer (2011) (15)
Corticosteroid-resistant bone marrow-derived B lymphocyte progenitor for long term in vitro cultures. (1986) (15)
kappa gene diversity among the clonal progeny of pre-B lymphocytes. (1984) (15)
BCR/ABL enhances growth of multipotent progenitor cells but does not block their differentiation potential in vitro. (1992) (15)
Cell lines and clinical isolates derived from Ph '-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration ( chromosome translocation / human leukemia / tyrosine kinase / oncogene ) (15)
Analysis of Bcr-Abl function using an in vitro embryonic stem cell differentiation system. (2002) (15)
Role of the ABL oncogene tyrosine kinase activity in human leukaemia. (1987) (15)
Development of 2-Deoxy-2-[(18)F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo. (2015) (14)
Role of the abl oncogene in chronic myelogenous leukemia. (1987) (13)
Direct observation of G-protein binding to the human δ-opioid receptor using plasmon-waveguide resonance spectroscopy. VOLUME 278 (2003) PAGES 48890-48897 (2005) (13)
P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells. (1989) (13)
Membrane proteins of MSV-MLV: their role in virion-virion interactions in vitro. (1974) (13)
Extending the utility of gene profiling data by bridging microarray platforms (2003) (12)
18F-FAC PET Visualizes Brain-Infiltrating Leukocytes in a Mouse Model of Multiple Sclerosis (2019) (12)
Establishment of a reproducible culture technique for the selective growth of B-cell progenitors. (1992) (12)
X-linked agammaglobulinemia and Bruton's tyrosine kinase. (1994) (11)
Androgen receptor (AR) amplification in patients (pts) with metastatic castration resistant prostate cancer (mCRPC) resistant to abiraterone (Abi) and enzalutamide (Enz): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). (2015) (11)
Retraction (2005) (11)
Title Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros Permalink (2013) (11)
Functions of the abl oncogene. (1986) (10)
18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis (2018) (10)
Application of a Rapid, Simple, and Accurate Adenovirus-Based Method to Compare PET Reporter Gene/PET Reporter Probe Systems (2013) (10)
HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses (2021) (10)
Closely related BCR/ABL oncogenes are associated with the distinctive clinical biologies of Philadelphia chromosome positive chronic myelogenous and acute lymphocytic leukemia. (1988) (10)
Evaluating the effect of P210 BCR/ABL on growth of hematopoietic progenitor cells and its role in the pathogenesis of human chronic myelogenous leukemia. (1993) (10)
Regulated progression of B lymphocyte differentiation from cultured fetal liver (1987) (10)
VH repertoire in progeny of long term lymphoid-cultured cells used to reconstitute immunodeficient mice. (1989) (9)
Haploinsufficiency of B cell linker protein enhances B cell signaling defects in mice expressing a limiting dosage of Bruton's tyrosine kinase. (2003) (9)
Synergism ofv-mycandv-Ha-ras intheInVitro Neoplastic Progression ofMurineLymphoid Cells (1986) (9)
Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team. (2016) (9)
GENETIC APPROACHES TO DEFINING SIGNALING BY THE CML-ASSOCIATED TYROSINE KINASE BCR-ABL (1994) (8)
,-Positive Leukemias 1 Model for Human Ph : A Novel Transgenic bcr / abl Disorder in Transgenic Mice Expressing p 210 Development of Acute Lymphoblastic Leukemia and Myeloproliferative (1998) (8)
BCR-ABL induces neurite-like structures and BCR lacking the SH2-binding domain induces cell rounding in PC12 cells. (1996) (7)
DSHP: a "power bar" for sustained immune responses? (1998) (7)
Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning (2021) (7)
Development of btk transgenic mice. (1995) (7)
Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET (2018) (7)
Unraveling Kinase Signaling Pathways with Chemical Genetic and Chemical Proteomic Approaches (2005) (6)
An in vitro model for tumor progression in murine lymphoid cells. (1986) (6)
760PDNEUROENDOCRINE PROSTATE CANCER (NEPC) IN PATIENTS (PTS) WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER (MCRPC) RESISTANT TO ABIRATERONE (ABI) OR ENZALUTAMIDE (ENZ): PRELIMINARY RESULTS FROM THE SU2C/PCF/AACR WEST COAST PROSTATE CANCER DREAM TEAM (WCDT). (2014) (6)
IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System (2018) (6)
3 – Long-Term Lymphoid Cultures in the Study of B-Cell Differentiation (1989) (6)
WITHDRAWN : SPHINGOSYLPHOSPHORYLCHOLINE AND LYSOPHOSPHATIDYLCHOLINE ARE LIGANDS FOR THE G PROTEIN COUPLED RECEPTOR GPR 4 * (2001) (6)
Got MLL? Definitive hematopoiesis requires MLL gene expression. (2004) (6)
Delay of Early B-Lymphocyte Development by Gamma 2b Immunoglobulin Transgene: Effect on Differentiation-Specific Molecules (1990) (6)
Neutralization of haptenated bacteriophage f2 by anti-hapten antibodies: direct evidence for a critical site. (1972) (5)
Lessons from human genetic variants in the study of B-cell differentiation. (1996) (5)
Links the Bcr-Abl Oncogene and Ras to the Stress-Activated Protein Kinase Pathway (1999) (5)
Linking the hematopoietic microenvironment to imatinib-resistant Ph+ B-ALL. (2007) (5)
A plethora of progenitors in the post‐natal prostate (2012) (5)
Characterization of Abelson murine leukemia virus isolates differing in P120 expression. (1980) (5)
A seminal finding for prostate cancer? (2010) (4)
The University of California, Los Angeles/Jennifer Jones Simon Foundation symposium on prostate cancer and epithelial cell biology: bringing together basic scientists and clinicians in the fight against advanced prostate cancer. (1998) (4)
Design and characterization of a biomedical device capable of pico-CI level beta detection for the study of cell metabolism (2008) (4)
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer (2022) (4)
Long-term culture systems for analysis of early B lymphocyte development. (1987) (4)
Preparation of Urogenital Sinus Mesenchymal Cells for Prostate Tissue Recombination Models. (2015) (4)
Erratum: Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4 (Journal of Biological Chemistry (2001) 276 (41325-41335)) (2005) (4)
Dissociated Prostate Regeneration under the Renal Capsule. (2015) (3)
IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing (2019) (3)
Tissue Recombination Models for the Study of Epithelial Cancer. (2015) (3)
Overcoming barriers to programming a therapeutic cellular immune response to fight melanoma (2010) (3)
Genetic approaches to defining signaling by the CML-associated tyrosine kinase BCR-ABL. (1994) (3)
Stem cell antigen of the prostate (PSCA). (1998) (2)
A Cloning Strategy to Identify Genes that Functionally Interact with Bcr-Abl for Transformation (1997) (2)
Regulation of B-cell differentiation by stromal cells (1995) (2)
Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation (2022) (2)
Model for Human Ph1-Positive Leukemias Disorder in Transgenic Mice Expressing p210 bcr/abl : A Novel Transgenic Development of Acute Lymphoblastic Leukemia and Myeloproliferative (2013) (2)
LinSca-1CD49f Stem/Progenitors Are Tumor-Initiating Cells in the Pten-Null Prostate Cancer Model (2009) (2)
The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells. (1991) (2)
Characterization of breakpoint cluster region kinase and SH2-binding activities. (1995) (2)
Functionality of clonal lymphoid progenitor cells expressing the P210 BCR/ABL oncogene. (1990) (2)
The role of multiple oncogenes in hematopoietic neoplasia. (1988) (2)
Tec/Btk Family Tyrosine Kinases (2004) (1)
Abstract 4985: Notch1 as a key mediator in promoting advanced castration-resistant prostate cancer (2015) (1)
A DISCREET EPITHELIAL POPULATION DERIVED FROM HUMAN PROSTATE TISSUE DEMONSTRATES STEM/PROGENITOR CELL ACTIVITY (2009) (1)
Pre-B cells in kappa-transgenic mice. (1985) (1)
Detection of antibody therapy-induced anti-tumor immune responses using anti-CD8 immuno-pet (2015) (1)
Oncogenes in the development of leukaemia (1993) (1)
Corrections: Induction of a Chronic Myelogenous Leukemia-Like Syndrome in Mice with v-abl and BCR/ABL (1990) (1)
Sensitive, Non‐Destructive Detection and Analysis of Neoantigen‐Specific T Cell Populations from Tumors and Blood (2018) (1)
Abstract A12: Identification of pathways associated with abiraterone resistance in metastatic castration resistant prostate cancer: Preliminary results from the SU2C/AACR West Coast Prostate Cancer Dream Team (2015) (1)
The molecular and pathway characterization of patients with metastatic castration resistant prostate cancer (mCRPC) refractory to therapy with abiraterone acetate or enzalutamide: Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). (2014) (1)
Oncogenes & Tumor Suppressors Interleukin-6 and Oncostatin-M Synergize with the PI 3 K / AKT Pathway to Promote Aggressive Prostate Malignancy in Mouse and Human Tissues (2013) (1)
Eosinophils Respond to Acidic environments with cAMP Generation in a TDAG8-Dependent Manner (2007) (1)
THE BCR-ABL STORY: Bench to Bedside (2003) (1)
bcr—abl: a model for leukemogenesis (1992) (0)
Local Prolactin is a Target to Prevent Expansion of Basal/Stem Cells in Prostate Tumors (2011) (0)
Evaluation of RET Tyrosine Kinase as a Novel Driver of Prostatic Small Cell Neuroendocrine Carcinoma (2015) (0)
Involvement of Bruton’s Tyrosine Kinase in Fc (cid:101) RI-dependent Mast Cell Degranulation and Cytokine Production (1998) (0)
Vesicular stomatitis virus glycoprotein isnecessary forH-2- restricted lysis ofinfected cells bycytotoxic Tlymphocytes (antigen recognition/viral immunity/temperature-sensitive mutants/cell surface antigens) (1978) (0)
Abstract PR5: Therapeutic targeting of oncogene-specific tyrosine kinase networks during prostate cancer progression (2012) (0)
Role of Ikaros in hematopoiesis and tumor suppression: Selective functions of individual zinc fingers within the DNA-binding domain of Ikaros. (42.3) (2012) (0)
Protein Tyrosine Kinases in Cancer Clinical Targeting of Mutated and Wild-Type (2014) (0)
The5'Noncoding Region oftheHumanLeukemia-Associated Oncogene BCRIABLIsa Potent Inhibitor ofInVitro Translation (1989) (0)
Abstract 3021: Roles of EMT on stem cell properties of prostate stem and cancer cells during castration-resistant prostate cancer progression (2014) (0)
ActivationTyrosine Kinases, Btk and Lyn, in Mast Cell Redundant and Opposing Functions of Two (2000) (0)
Abstract SY05-01: Non-immunogenic PET reporter imaging of HSC transplants and T cell immunotherapies (2015) (0)
Positive and Negative Growth Effects of Abl Genes (1995) (0)
Isolation and Characterization of Prostate Stem Cells (2013) (0)
Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes ( antigen recognition / viral immunity / temperature-sensitive mutants / cell surface antigens ) (2003) (0)
Abstract IA17: Stem cells and prostate cancer (2012) (0)
530: Defining Human Prostate Stem Cells Via Development and Characterization of Prostaspheres (2007) (0)
Posttranscriptional regulal kinase expression in antig splenic B cells (2016) (0)
ABELSON MURINE LEUKEMIA-VIRUS AND HELPER VIRUS INTERACTION WITH DIFFERENTIATED CELLS (1978) (0)
Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation (1987) (0)
Title Immuno-PET of Murine T Cell Reconstitution Postadoptive Stem Cell Transplantation Using Anti-CD 4 and Anti-CD 8 Cys-Diabodies Permalink (2015) (0)
Development of cells of the B-lymphocyte lineage in longterm culture. (1984) (0)
- Abl: c-Abl protein-tyrosine kinase (vertebrates) (1995) (0)
Abstract 4964: Signaling through the progesterone receptor in the tumor microenvironment regulates hormonal sensitivity in endometrial carcinoma. (2013) (0)
The molecular pathogenesis of XLA involves a spectrum of mutations in Bruton's tyrosine kinase (1994) (0)
Abstract B57: Oncostatin M promotes progression of Pten-deficient prostate cancer (2012) (0)
Molecular cloning and serological characterization of an altered c-abl gene product produced in Ph1 CML patients. (1987) (0)
Chronic Myelogenous Leukemia as a Model System for Stem Cell Growth Regulation and Hematolymphoid Development (1986) (0)
Erratum: Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells (Proceedings of the National Academy of Sciences of the United States of America (March 14, 2000) 97 (2737-2742)) (2000) (0)
The ABL Oncogene and Kinase Targeted Therapies (2018) (0)
RAPID COMMUNICATION In Vitro Reconstitution of Human B-Cell Ontogeny: From CD341 Multipotent Progenitors to Ig-Secreting Cells (1998) (0)
transfer of X-linked agammaglobulinemia ( XLA ) using retroviral-mediated gene Sustained correction of B cell development and function in a murine model (2004) (0)
Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis (2022) (0)
Growth, regeneration, and tt prostate activates the PSCA (2016) (0)
Engineering antigen-specific T cells for in vivo imaging: A study of the dynamic biological interactions in anti-tumor immunity (2007) (0)
A functional screen for regulators of the c-Abl protein tyrosine kinase. (1997) (0)
Evolution of the Leukemic State Group Report (1985) (0)
Phospho-proteomics reveals oncogenic phospho-tyrosine signaling networks in cancers lacking mutated or amplified tyrosine kinases (2013) (0)
Abstract SY03-04: Novel imaging approaches for immunotherapy and targeted therapy of melanoma in animal models and humans (2011) (0)
IA23 Developing New Therapies in Small-Cell Lung Cancer Using Parallel Clinical and Laboratory-Based Studies (2020) (0)
T-Cell Death-Associated Gene 8 Critically Regulates Airway Eosinophilia in Allergen-Challenged Mice (2007) (0)
MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer (2019) (0)
B cell development : proceedings of an Abbott-Ortho-UCLA symposium held at Taos, New Mexico, January 31-February 7, 1988 (1988) (0)
IA20 Pan-Cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematologic Malignancies (2020) (0)
Initiation of Deregulated Growth of Multipotent Progenitor Cells by bcr-abl in Vitro (1992) (0)
The comprehensive methylation landscape of metastatic castration-resistant prostate cancer (mCRPC) identifies new phenotypic subtypes: Results from the West Coast Prostate Cancer Dream Team (WCDT). (2020) (0)
Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene (1991) (0)
Abstract LB-279: N-cadherin promotes castration-resistant prostate cancer progression by enhancing stem cell properties of prostate cancer cells (2016) (0)
In situ detection of activated Bru Ig signaling complex by phosphol monoclonal antibodies (2016) (0)
Abstract 4839: Adoptive cell transfer of transgenic T cells elicited a two-wave antitumor cellular immune response consisted of engineered and endogenous T lymphocytes with different sets of functions (2012) (0)
Abstract SY13-03: Signal pathways in prostate cancer stem cells (2014) (0)
Analysis of Ikaros tumor suppressor function in BCR-ABL1+ pre-B ALL reveals conserved target genes and biological pathways (2016) (0)
Pathway-based signature analysis of RNA-seq data to reveal new targetable avenues for metastatic castration-resistant prostate cancer (mCRPC) patients (pts): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). (2014) (0)
Low CD 38 Identifies Proge nitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome Graphical Abstract Highlights (2016) (0)
5-(2-[F]FLUOROETHYL)-4-METHYLTHIAZOLE PROBE FOR POSITRON EMISSION TOMOGRAPHY OF THE CENTRAL NERVOUS SYSTEM (2014) (0)
For the article ‘ ‘ An advanced glycation end-product cross-link breaker can reverse age-related increases in myocardial stiffness (2000) (0)
Molecular profiling of metastatic castration-resistant prostate cancer (mCRPC): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). (2014) (0)
Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration (2016) (0)
Urological Survey Uro-Science Re : Cellular Uptake and Anticancer Activity of Carboxylated Gallium (2016) (0)
Abstract 2438: Determining the role of non-mutated C-Raf kinase in metastatic disease (2022) (0)
Molecular Cloning and Serological Characterization of an Altered c-abl Gene Product Produced in PhI CML Patients (2005) (0)
gene transfer model of X-linked agammaglobulinemia (XLA) using retroviral-mediated Sustained correction of B-cell development and function in a murine (2012) (0)
Abstract 3604: PSC-derived T cells as a novel source of tumor antigen-specific T cell receptors (2022) (0)
Abstract B67: The epigenetic regulator Hmga2 is sufficient to initiate prostate cancer via paracrine Wnt signaling (2012) (0)
BCR y ABL inhibition by an escort y phosphatase fusion protein (2000) (0)
A Pre-Clinical Model Of Hematopoietic Stem Cell Based Immunotherapy For Cancer Utilizing The NY-ESO-1 T-Cell Receptor and sr39TK PET Reporter / Suicide Gene (2013) (0)
Acid Assembled p / MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells (2009) (0)
Identification and Targeting of Tyrosine Kinase Activity in Prostate Cancer Initiation, Progression, and Metastasis (2012) (0)
PET Imaging in Immunology (2017) (0)
Prostate stem cell antigen (PSCA) and uses thereof (1999) (0)
Gene expression of Abelson murine leukemia virus. (1980) (0)
Imaging in Immunology Research (2011) (0)
High-Throughput Screening of T Cell Cytotoxic Events by Biomass Profiling (2014) (0)
5-(2-[18 F]Fluoroethyl)-4-Methylthiazole Probe For Positron Emission Tomography Of The Central Nervous System (2014) (0)
Defining T cell receptor repertoires using nanovial-based affinity and functional screening (2023) (0)
Book Review:RNA Tumor Viruses. Molecular Biology of Tumor Viruses. Robin Weiss, Natalie Teich, Harold Varmus, John Coffin (1983) (0)
catenin signaling β stem cell self-renewal via Regulated proteolysis of Trop 2 drives epithelial hyperplasia and Material Supplemental (2012) (0)
Immunoglobulin Transgene" Effect on Differentiation- Specific Molecules (1990) (0)
Targeting glycogen synthase kinase-3 (GSK-3) in human melanoma (2008) (0)
MP57-09 MOLECULAR PROFILING OF SMALL CELL BLADDER CANCER: IMPLICATIONS FOR IMMUNOTHERAPEUTIC STRATEGIES (2019) (0)
T cell antigen discovery via trogocytosis (2019) (0)
The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells (2022) (0)
Discovery of New Therapeutic Targets for Prostate Cancer (2014) (0)
Monitoring Cellular Interactions during T Cell Activation at the Single Molecule Level Using Semiconductor Quantum-Dots (2005) (0)
Chapter 2 Isolation and Characterization of Prostate Stem Cells (2017) (0)
Consequences ofBCR‐ABL Expression within theHematopoieticStemCell inChronicMyeloidLeukemia (2001) (0)
Generation of Lenti-Virus Mediated JNK and Apoptosis Inducing Factor (AIF) Knockout Cell Lines: Involvement of JNK & AIF in FAS and TNF-Alpha Mediated Cell Death Pathways (2006) (0)
Abstract A28: N-Myc drives small cell neuroendocrine cancer initiated from human prostate basal cells (2015) (0)
Phosphoinositide 3-kinase signaling is essential for ABL oncogene mediated transformation of B lineage cells SHORT TITLE FOR RUNNING HEADING: Role of PI3K in ABL transformation AUTHORS: (2004) (0)
148 Identification of prostate-restricted epithelial antigens for transgenic T cell adoptive therapy against prostate cancer (2020) (0)
Comparison of the sequence of the bcr coding region (2003) (0)
Abstract 5539: Low levels of estrogen sensitize PTEN-deficient endometrial tumors to poly-ADP ribose polymerase (PARP) inhibitionin vivo. (2013) (0)
Abstract 1860: DNA-PK-mediated transcriptional regulation drives tumor progression and metastasis (2015) (0)
- Bcr: Bcr serine/threonine PK (vertebrates) (1995) (0)
Abstract 5183: Identification and characterization of wild type kinases driving prostate cancer metastasis (2015) (0)
IA22 Identifying Chemically Tractable Vulnerabilities in Small-Cell Lung Cancer (2020) (0)
Molecular Imaging with Reporter Genes: Imaging Cell Trafficking and Immune Cell Activation Using PET Reporter Genes (2010) (0)
by Cytotoxic T Lymphocytes Vesicular Stomatitis Virus Glycoprotein is Necessary for H-2-Restricted Lysis of Infected Cells (2003) (0)
Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the oncogene. (2003) (0)
Structural Characteristics ofSomeMurineRNA TumorViruses Studied byLactoperoxidase lodination (radiation leukemiavirus/Moloney leukemiavirus/mouse mammary tumorvirus/gel electrophoresis) (1973) (0)
Bringing Together Basic Scientists and Clinicians in the Fight against Advanced Prostate Cancer 1 (2006) (0)
Involvement of the abl oncogene in human chronic myelogenous leukemia. (1986) (0)
A TYPE II TRANSMEMBRANE GLYCOPROTEIN ASSOCIATED WITH OSTEOGENESIS CAN ACCELERATE ANDROGEN-INDEPENDENT PROSTATE CANCER PROGRESSION IN VIVO (1999) (0)
F ] FLUOROETHYL )-4-METHYLTHIAZOLE PROBE FOR POSITRON EMISSION TOMOGRAPHY OF THE CENTRAL NERVOUS SYSTEM (2014) (0)
Microenvironment and Immunology Progesterone Receptor Signaling in theMicroenvironment of Endometrial Cancer In fl uences Its Response to Hormonal Therapy (2013) (0)
Abstract C70: Trop2 regulates prostate tumorigenesis and stem cell self-renewal (2012) (0)
Hyperexpression ofInterleukin-7 IsNotNecessary orSufficient for Transformation ofa Pre-BLymphoid CellLine (1991) (0)

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