Philippe A. Halban
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Philosophy Biology
Philippe A. Halban's Degrees
- PhD Biochemistry University of Geneva
- Doctorate Medicine University of Geneva
Why Is Philippe A. Halban Influential?
(Suggest an Edit or Addition)Philippe A. Halban's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. (1992) (1088)
- Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. (2002) (732)
- Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells (2011) (716)
- Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis* (2003) (549)
- Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications (2004) (428)
- β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment (2014) (402)
- Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. (2002) (384)
- Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. (2003) (325)
- Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. (2008) (312)
- Sorting and processing of secretory proteins. (1994) (302)
- Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets. (2004) (253)
- Proliferation of sorted human and rat beta cells (2007) (245)
- SNAP-25 is expressed in islets of Langerhans and is involved in insulin release (1995) (238)
- Regulation of immunoreactive-insulin release from a rat cell line (RINm5F). (1983) (222)
- Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse. (2003) (218)
- Cytokine production by islets in health and diabetes: cellular origin, regulation and function (2010) (216)
- Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin. (2000) (211)
- Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat (2006) (192)
- The possible importance of contact between pancreatic islet cells for the control of insulin release. (1982) (190)
- Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways. (2004) (187)
- Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway (1987) (176)
- Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex. (2003) (176)
- Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome (2013) (163)
- FLIP switches Fas-mediated glucose signaling in human pancreatic β cells from apoptosis to cell replication (2002) (157)
- Regulation of pancreatic β-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway (2006) (153)
- Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content. (1980) (148)
- Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe β-Cell Loss in Munich Ins2C95S Mutant Mice (2007) (140)
- A clathrin-coated, golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin (1984) (138)
- Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. (2003) (138)
- Spontaneous Reassociation of Dispersed Adult Rat Pancreatic Islet Cells Into Aggregates With Three-Dimensional Architecture Typical of Native Islets (1987) (135)
- Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. (1994) (134)
- Insulin resistance in HIV protease inhibitor-associated diabetes. (1999) (132)
- Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell (1984) (127)
- β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. (2014) (125)
- Interleukin-6 regulates pancreatic α-cell mass expansion (2008) (123)
- Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix (2006) (111)
- Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. (1999) (108)
- Mutational analysis of VAMP domains implicated in Ca2+‐induced insulin exocytosis. (1996) (106)
- Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle (2011) (105)
- Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells. (2001) (105)
- Pioglitazone and sodium salicylate protect human β-cells against apoptosis and impaired function induced by glucose and interleukin-1β (2004) (104)
- Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? (2001) (104)
- SNAP-23 Is Not Cleaved by Botulinum Neurotoxin E and Can Replace SNAP-25 in the Process of Insulin Secretion* (1997) (104)
- Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta‐Cell (2004) (101)
- Current status of islet cell replacement and regeneration therapy. (2010) (101)
- Impaired NH2-Terminal Processing of Human Proislet Amyloid Polypeptide by the Prohormone Convertase PC2 Leads to Amyloid Formation and Cell Death (2006) (99)
- Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types. (1991) (99)
- Cellular sources of new pancreatic β cells and therapeutic implications for regenerative medicine (2004) (99)
- Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro (2002) (98)
- Abnormal glucose metabolism accompanies failure of glucose to stimulate insulin release from a rat pancreatic cell line (RINm5F). (1983) (97)
- Functional differences between rat islets of ventral and dorsal pancreatic origin. (1982) (96)
- Autonomous and self-sustained circadian oscillators displayed in human islet cells (2012) (96)
- Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types. (1990) (96)
- Activation of NF-κB by Extracellular Matrix Is Involved in Spreading and Glucose-stimulated Insulin Secretion of Pancreatic Beta Cells* (2005) (95)
- In Vivo Modulation of Gap Junctions and Dye Coupling Between B-Cells of the Intact Pancreatic Islet (1983) (95)
- Role of β-Cell Prohormone Convertase (PC)1/3 in Processing of Pro-Islet Amyloid Polypeptide (2004) (93)
- Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor (2002) (90)
- Novel Insulinoma Cell Lines Produced by Iterative Engineering of GLUT2, Glucokinase, and Human Insulin Expression (1997) (90)
- Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion. (2008) (88)
- Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells (2005) (88)
- The Fas pathway is involved in pancreatic β cell secretory function (2007) (87)
- Storage of tissue-type plasminogen activator in Weibel-Palade bodies of human endothelial cells. (1999) (80)
- Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio. (2016) (79)
- Gap junction development is correlated with insulin content in the pancreatic B cell. (1980) (79)
- pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle (1994) (77)
- Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic Beta cell (1991) (75)
- Long-term exposure of isolated pancreatic islets to mannoheptulose: Evidence for insulin degradation in the β cell (1980) (75)
- Differential rates of release of newly synthesized and of stored insulin from pancreatic islets. (1982) (74)
- A new, rapid, method for preparation of dispersed pancreatic acini. (1985) (70)
- Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity. (2007) (69)
- B-cell size influences glucose-stimulated insulin secretion. (1993) (67)
- Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin (2011) (67)
- Chronic central neuropeptide Y infusion in normal rats: status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia (1997) (66)
- Importance of Cell-Matrix Interactions in Rat Islet-Cell Secretion In Vi t r o Role of 6 1 Integrin (2000) (66)
- Insulin degradation by hepatocytes in primary culture. (1981) (66)
- Trafficking/sorting and granule biogenesis in the beta-cell. (2000) (65)
- Identification and Characterization of α3β1 Integrin on Primary and Transformed Rat Islet Cells (1997) (64)
- Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14 (2008) (63)
- Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion* (2011) (63)
- Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump. (1987) (63)
- Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix. (2006) (62)
- Small Interfering RNA–Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture (2008) (61)
- NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro (2001) (61)
- Munc 18‐1 and Granuphilin Collaborate During Insulin Granule Exocytosis (2008) (60)
- Processing of proinsulin by transfected hepatoma (FAO) cells. (1992) (60)
- Absorption kinetics of subcutaneously injected insulin (1979) (59)
- Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function. (2009) (59)
- Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation. (1998) (57)
- Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1beta. (2004) (56)
- Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide. (2004) (56)
- Isolation of pancreatic islets and primary culture of the intact microorgans or of dispersed islet cells. (1990) (56)
- Nonconverted, amino acid analog-modified proinsulin stays in a Golgi- derived clathrin-coated membrane compartment (1984) (55)
- Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells. (2007) (55)
- Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells. (2005) (55)
- b-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and (2014) (55)
- In Vitro Proliferation of Adult Human Beta-Cells (2012) (54)
- Pharmacokinetics of Subcutaneously Injected Tritiated Insulin: Effects of Exercise (1979) (54)
- Intracellular pathways of insulin transport across vascular endothelial cells. (1988) (52)
- Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells. (1994) (52)
- Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells. (1989) (51)
- Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription (2003) (51)
- Membrane localization and biological activity of SNAP-25 cysteine mutants in insulin-secreting cells. (2000) (49)
- Silencing Mitogen-activated Protein 4 Kinase 4 (MAP4K4) Protects Beta Cells from Tumor Necrosis Factor-α-induced Decrease of IRS-2 and Inhibition of Glucose-stimulated Insulin Secretion* (2009) (49)
- Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells (2008) (49)
- The skeleton in the closet: actin cytoskeletal remodeling in β-cell function. (2015) (49)
- Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix. (2009) (48)
- Effects of aging on insulin synthesis and secretion. Differential effects on preproinsulin messenger RNA levels, proinsulin biosynthesis, and secretion of newly made and preformed insulin in the rat. (1988) (47)
- SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion. (1999) (47)
- Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus. (1996) (46)
- Proinsulin processing in the regulated and the constitutive secretory pathway (1994) (45)
- Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited. (1996) (44)
- Kinetics of Proinsulin Conversion in Human Islets (1993) (43)
- Sorting human beta-cells consequent to targeted expression of green fluorescent protein. (1998) (43)
- Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14. (2008) (43)
- Dynamin Is Functionally Coupled to Insulin Granule Exocytosis* (2007) (43)
- Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells (2000) (43)
- The Effect of Aprotinin on the Absorption of Subcutaneously Injected Regular Insulin in Normal Subjects (1980) (42)
- Proinsulin Conversion in GH3 Cells After Coexpression of Human Proinsulin With the Endoproteases PC2 and/or PC3 (1997) (40)
- Dispersed adult rat pancreatic islet cells in culture: A, B, and D cell function. (1984) (40)
- Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion. (2002) (36)
- Human proinsulin conversion in the regulated and the constitutive pathways of transfected AtT20 cells. (1994) (36)
- Identification and characterization of alpha 3 beta 1 integrin on primary and transformed rat islet cells. (1997) (35)
- Identification of functional insulin receptors on membranes from an insulin-producing cell line (RINm5F). (1985) (35)
- Processing of Proinsulin by Furin, PC2, and PC3 in (Co) Transfected COS (Monkey Kidney) Cells (1995) (34)
- Role of clathrin in the regulated secretory pathway of pancreatic beta-cells. (2001) (32)
- Elevated Proinsulin Biosynthesis In Vitro from a Rat Model of Non-insulin-dependent Diabetes Mellitus (1983) (32)
- Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion (2013) (32)
- The preparation of a semisynthetic tritiated insulin with a specific radioactivity of up to 20 Curies per millimole. (1975) (32)
- Increased clearance and degradation of [3H]insulin in streptozotocin diabetic rats. (1981) (32)
- Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II. (1991) (32)
- Binding and Degradation of Semisynthetic Tritiated Insulin by IM-9 Cultured Human Lymphocytes (1980) (31)
- Deletion of a highly conserved tetrapeptide sequence of the proinsulin connecting peptide (C-peptide) inhibits proinsulin to insulin conversion by transfected pituitary corticotroph (AtT20) cells. (1989) (31)
- Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix. (2001) (31)
- Novel, non-crinophagic, degradation of connecting peptide in transformed pancreatic beta cells. (1993) (31)
- Resistance of the insulin crystal to lysosomal proteases: implications for pancreatic B-cell crinophagy (1987) (31)
- Tumor necrosis factor-alpha modifies adhesion properties of rat islet B cells. (1993) (30)
- Perturbation of hormone storage and release induced by cyproheptadine in rat pancreatic islets in vitro. (1979) (30)
- Slow cleavage at the proinsulin B-chain/connecting peptide junction associated with low levels of endoprotease PC1/3 in transformed beta cells. (1993) (28)
- Influence of Glucose on Insulin Handling by Rat Islets in Culture: A Reflection of Integrated Changes in Insulin Biosynthesis, Release, and Intracellular Degradation (1983) (28)
- Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα (2014) (26)
- Pro-Survival Role of Gelsolin in Mouse β-Cells (2007) (26)
- RESISTANCE AGAINST SUBCUTANEOUS INSULIN SUCCESSFULLY MANAGED WITH APROTININ (1980) (26)
- Hypoglycaemia caused by atypical insulin antibodies in a patient with benign monoclonal gammopathy (1993) (26)
- Des-(27-31)C-Peptide (1996) (25)
- Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products. (1982) (25)
- The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs (1992) (24)
- The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide. (1988) (22)
- Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression* (2015) (21)
- Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat (2011) (21)
- Sequence requirements for proinsulin processing at the B-chain/C-peptide junction. (1995) (21)
- Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model (2013) (21)
- Regenerating 1 and 3b Gene Expression in the Pancreas of Type 2 Diabetic Goto-Kakizaki (GK) Rats (2014) (21)
- Bimodal impact of skeletal muscle on pancreatic β‐cell function in health and disease (2012) (21)
- IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death (2015) (20)
- Glucose-induced b cell production of IL-1 b contributes to glucotoxicity in human pancreatic islets (2018) (20)
- Proinsulin trafckin and processing in the pancreatic B cell (1990) (19)
- In Vitro Studies on Biosynthetic Human Insulin: an Overview (1981) (18)
- Pro-survival role of gelsolin in mouse beta-cells. (2007) (17)
- Inhibition of degradation of insulin by ophthalamic acid and by a bovine pancreatic proteinase inhibitor. (1979) (16)
- Mobilization of subcutaneously injected tritiated insulin in rats: Effects of muscular exercise (1978) (16)
- Mutant proinsulin that cannot be converted is secreted efficiently from primary rat beta-cells via the regulated pathway. (2003) (15)
- The degradation of semisynthetic tritiated insulin by perfused mouse livers. (1976) (15)
- Establishment and culture of insulin-secreting beta cell lines. (1990) (15)
- Altered differentiated cell surface properties of transformed (RINm5F) compared with native adult rat pancreatic B cells. (1988) (15)
- DIAMAP: A Road Map for Diabetes Research in Europe (2011) (14)
- Diabetes research investment in the European Union (2006) (14)
- Heterogeneity of expression and secretion of native and mutant [AspB10]insulin in AtT20 cells. (1991) (13)
- Cell therapy for type 2 diabetes: is it desirable and can we get it? (2008) (13)
- Distribution and metabolism of intravenously injected tritiated insulin in rats. (1979) (13)
- Adaptation to supraphysiologic levels of insulin gene expression in transgenic mice: evidence for the importance of posttranscriptional regulation. (1993) (12)
- Bimodal Effect on Pancreatic β-Cells of Secretory Products From Normal or Insulin-Resistant Human Skeletal Muscle. Diabetes 2011;60:1111–1121 (2014) (12)
- Glucagon-like Peptide-1 Receptor Signaling Modulates (2002) (11)
- High-performance liquid chromatography analysis of circulating insulins distinguishes between endogenous insulin production (a potential pitfall with streptozotocin diabetic rats) and islet xenograft function (1990) (11)
- High-performance liquid chromatography (HPLC): A rapid, flexible and sensitive method for separating islet proinsulin and insulin (1986) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Truncated (des-[27–31]) C-peptide is not a major secretory product of human islets (2002) (11)
- The GM2-1 Ganglioside Islet Autoantigen in Insulin-Dependent Diabetes Mellitus Is Expressed in Secretory Granules and Is Notβ -Cell Specific. (1998) (11)
- Isolation of pancreatic islets of Langerhans by filtration on nylon mesh. (1978) (10)
- In vitro and in vivo studies on glucagonoma tissue. (1980) (10)
- Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression. (2015) (10)
- Substrate specificity of proinsulin conversion in the constitutive pathway of transfected FAO (hepatoma) cells (1993) (9)
- Islet B-cell dysfunction and the time course of recovery following chronic overinsulinisation of normal rats (1988) (9)
- Role of clathrin in the regulated secretory pathway of pancreatic β-cells (9)
- SNAP-25 can self-associate to form a disulfide-linked complex. (1997) (9)
- Molecular strategies for the treatment of diabetes. (1994) (8)
- Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells. (1984) (8)
- 50 years forward: beta cells (2015) (8)
- Prime time for DIAMAP: a road map for diabetes research in Europe (2010) (8)
- The GM2-1 ganglioside islet autoantigen in insulin-dependent diabetes mellitus is expressed in secretory granules and is not beta-cell specific. (1998) (8)
- Diabetes resistant to subcutaneous insulin: effect of aprotinin. (1981) (7)
- Long-term exposure of isolated pancreatic islets to mannoheptulose: evidence for insulin degradation in the beta cell. (1980) (7)
- The Chemical Characterization of the Products of the Processing of Subcutaneously Injected Insulin (1980) (6)
- Order! Order! Order in the House! (2008) (5)
- Production of insulin antibodies by mice rejecting insulin transfected cells. (1989) (4)
- Tris(hydroxymethyl)aminomethane Inhibits the Synthesis and Processing of Proinsulin in Isolated Rat Pancreatic Islets Without Affecting Release of Insulin Stores (1986) (4)
- Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN). (1989) (4)
- Sorting Human -Cells Consequent to Ta r g e t e d Expression of Green Fluorescent Protein (1998) (4)
- Insulin production: from gene to granule (1997) (3)
- Comparison of 125 I-Insulin and [B1- 3 H-Phenylalanine]- Insulin Degradation by Insulin Protease (1980) (2)
- Proinsulin conversion intermediates: a possible source of confusion (1991) (2)
- Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045—3055 (2016) (2)
- Activation of liver and muscle insulin receptor tyrosine kinase activity during in vivo insulin administration in rats (1990) (2)
- DIAMAP: an innovative blueprint for the future of diabetes research in Europe (2010) (2)
- Towards a perfect beta cell replacement. (2004) (2)
- GLUT2 or not GLUT2? That is the question (1997) (2)
- 10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it? (2005) (2)
- A road map for European diabetes research: DIAMAP (2008) (2)
- The innovative medicines initiative (IMI): a shot in the arm for European diabetes research? (2007) (2)
- A new paradigm for improved co-ordination and efficacy of European biomedical research: taking diabetes as a model (2013) (1)
- Degradation of pork insulin and biosynthetic human insulin in vitro and in vivo: a comparative study. (1981) (1)
- Insulin production: from gene to granule (1997) (1)
- Publish and flourish: seasonal advice to our readers (1995) (1)
- Rab-GAP AS160 is a major downstream effector of PKB/Akt signaling in pancreatic beta-cells (2008) (1)
- [How to explain the rebirth of the beta cell in terms of sacrifice and delivery]. (2007) (0)
- Thank you Vienna—over to you, Bristol (2004) (0)
- EASD News Sections October 2002 (2002) (0)
- Leptin modulates (cid:1) cell expression of IL-1 receptor antagonist and release of IL-1 (cid:1) in human islets (2004) (0)
- Comment faire renaître la cellule beta du sacrifice en sauveur (2007) (0)
- Immunofluorescence analysis of t-PA in human endothelial cells (1998) (0)
- [Biosynthesis of insulin: intracellular traffic and enzymatic transformations]. (1991) (0)
- Editorial Board (1992) (0)
- study of substrate specificity in the conversion of proinsulin by PC 3 . MATERIALS AND METHODS Materials The expression (2005) (0)
- Sponsor, leader and lobbyist: The European Foundation for the Study of Diabetes (EFSD) and the future of diabetes research in Europe (2000) (0)
- The right stuff: (cid:1) -cell channels, cycles, and sensors (2008) (0)
- Editorial Board (2010) (0)
- The right stuff: beta-cell channels, cycles, and sensors. (2008) (0)
- Levels of the conversion endoproteases PCi (PC3) and PC2 distinguish between insulin-producing pancreatic islet cells and non-f cells (2005) (0)
- Focal adhesion remodelling is crucial for glucose-stimulated insulin secretion in pancreatic beta cells (2011) (0)
- TT Proinsulin in the Same Secretory Vesicle (1994) (0)
- Biosynthèse de l'insuline: trafic intracellulaire et transformations enzymatiques (1991) (0)
- Erratum to: Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model (2013) (0)
- Focal Adhesion Kinase (FAK) activity is crucial for beta cell glucose-stimulated insulin secretion (2009) (0)
- Some Inhibitors of Insulin Degradation (1980) (0)
- (cid:2) -Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment (2014) (0)
- SORTING OF PROTEINS DESTINED FOR THE REGULATED SECRETORY PATHWAY (2005) (0)
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