Paul Bornstein
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Biology
Paul Bornstein's Degrees
- PhD Neuroscience University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Paul Bornstein's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Thrombospondins Are Astrocyte-Secreted Proteins that Promote CNS Synaptogenesis (2005) (1491)
- Matricellular proteins: extracellular modulators of cell function. (2002) (928)
- Structurally distinct collagen types. (1980) (919)
- Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1 (1995) (636)
- THE ELASTIC FIBER: I. The Separation and Partial Characterization of its Macromolecular Components (1969) (632)
- Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin. (1991) (527)
- Mice That Lack Thrombospondin 2 Display Connective Tissue Abnormalities That Are Associated with Disordered Collagen Fibrillogenesis, an Increased Vascular Density, and a Bleeding Diathesis (1998) (473)
- Thrombospondins as matricellular modulators of cell function. (2001) (445)
- Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo (2005) (427)
- Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. (1988) (403)
- Dynamic reciprocity in the wound microenvironment (2011) (393)
- Thrombospondins: structure and regulation of expression (1992) (327)
- The nature of the intramolecular cross-links in collagen. The separation and characterization of peptides from the cross-link region of rat skin collagen. (1966) (303)
- Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis. (1999) (298)
- Thrombospondins 1 and 2 function as inhibitors of angiogenesis. (2003) (288)
- The biosynthesis of collagen. (1974) (288)
- The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. (2002) (280)
- Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. (1991) (274)
- Extracellular Matrix Metalloproteinase 2 Levels Are Regulated by the Low Density Lipoprotein-related Scavenger Receptor and Thrombospondin 2* (2001) (269)
- Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. (1986) (251)
- Light microscopic immunolocation of thrombospondin in human tissues. (1985) (250)
- Thrombospondin: synthesis and secretion by cells in culture (1982) (245)
- [14] Cleavage at AsnGly bonds with hydroxylamine (1977) (243)
- Matricellular proteins: an overview (2009) (243)
- Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. (1984) (242)
- Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. (1993) (224)
- The Low Density Lipoprotein Receptor-related Protein Modulates Levels of Matrix Metalloproteinase 9 (MMP-9) by Mediating Its Cellular Catabolism* (2001) (222)
- Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn. (1981) (216)
- Differential expression of thrombospondin 1, 2, and 3 during murine development (1993) (215)
- Structural studies on human type IV collagen. (1979) (210)
- Sulfated proteoglycans synthesized by vascular endothelial cells in culture. (1983) (210)
- 4 – The Chemistry and Biology of Collagen (1979) (210)
- Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells (1985) (209)
- EFFECTS OF ANTIMICROTUBULAR AGENTS ON THE SECRETION OF COLLAGEN (1974) (207)
- The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. (2004) (204)
- The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injury. (2004) (202)
- Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission (1997) (201)
- Correlation of procollagen mRNA levels in normal and transformed chick embryo fibroblasts with different rates of procollagen synthesis. (1978) (200)
- Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2. (2000) (198)
- Thrombospondin-2 Is Essential for Myocardial Matrix Integrity: Increased Expression Identifies Failure-Prone Cardiac Hypertrophy (2004) (196)
- X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity. (1980) (191)
- Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture. Apparent identity with platelet thrombospondin. (1981) (190)
- Thrombospondins function as regulators of angiogenesis (2009) (186)
- Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen (1984) (185)
- pH-sensitive polymers that enhance intracellular drug delivery in vivo. (2002) (177)
- Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis. (2004) (174)
- Thrombospondin‐1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor‐related protein‐1 (LRP‐1) (2007) (169)
- Regulation of collagen gene expression. (1989) (168)
- Characterization of a novel collagen chain in human placenta and its relation to AB collagen. (1979) (168)
- Microtubules in transcellular movement of procollagen. (1972) (167)
- Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. (1999) (162)
- Isolation of a collagen-binding fragment from fibronectin and cold-insoluble globulin. (1979) (158)
- Isolation and characterization of the cyanogen bromide peptides from the alpha-1 chain of rat skin collagen. (1967) (154)
- Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. (2009) (153)
- Matricellular proteins as modulators of wound healing and the foreign body response (2003) (153)
- TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax (2007) (153)
- SPARC Regulates Processing of Procollagen I and Collagen Fibrillogenesis in Dermal Fibroblasts* (2007) (150)
- Thrombospondin 2, a matricellular protein with diverse functions. (2000) (149)
- Impaired conversion of procollagen to collagen by fibroblasts and bone treated with tunicamycin, an inhibitor of protein glycosylation. (1977) (146)
- Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. (1999) (144)
- Secretory Phenotypes of Endothelial Cells in Culture Comparison of Aortic, Venous, Capillary, and Corneal Endothelium (1981) (141)
- Thrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium. (1996) (137)
- Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9 (2009) (137)
- Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen gene. (1987) (135)
- Evidence for procollagen, a biosynthetic precursors of collagen. (1971) (133)
- Synthesis of types I and III procollagen and collagen by monkey aortic smooth muscle cells in vitro. (1977) (131)
- Collagen synthesis by bovine aortic endothelial cells in culture. (1979) (129)
- The amino acid sequence of peptides from the cross-linking region of rat skin collagen. (1967) (127)
- A BIOCHEMICAL STUDY OF HUMAN SKIN COLLAGEN AND THE RELATION BETWEEN INTRA- AND INTERMOLECULAR CROSS-LINKING. (1964) (126)
- Metaxin Is a Component of a Preprotein Import Complex in the Outer Membrane of the Mammalian Mitochondrion* (1997) (125)
- Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-containing peptide in a similar manner. (1982) (124)
- Regulation of expression of the type I collagen genes. (1993) (123)
- The nature and location of intramolecular cross-links in collagen. (1966) (122)
- Comparative sequence studies of rat skin and tendon collagen. I. Evidence for incomplete hydroxylation of individual prolyl residues in the normal proteins. (1967) (119)
- Interactions between CD47 and Thrombospondin Reduce Inflammation1 (2007) (117)
- A unique, pepsin-sensitive collagen synthesized by aortic endothelial cells in culture. (1980) (114)
- Cell surface-associated structural proteins in connective tissue cells. (1977) (114)
- Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice. (2001) (111)
- Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes. (1982) (108)
- Regulation of thrombospondin secretion by cells in culture (1984) (106)
- Studies of morphologically atypical (“sprouting”) cultures of bovine aortic endothelial cells. Growth characteristics and connective tissue protein synthesis (1980) (106)
- Thrombospondin 2 Inhibits Microvascular Endothelial Cell Proliferation by a Caspase-independent Mechanism (2002) (106)
- Changes in surface properties of normal and transformed cells caused by tunicamycin, an inhibitor of protein glycosylation. (1977) (106)
- Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. (2006) (104)
- Interactions between the promoter and first intron are involved in transcriptional control of alpha 1(I) collagen gene expression (1988) (103)
- Structure of alpha-1-CB8, a large cyanogen bromide produced fragment from the alpha-1 chain of rat collagen. The nature of a hydroxylamine-sensitive bond and composition of tryptic peptides. (1970) (100)
- Type VIII collagen has a restricted distribution in specialized extracellular matrices (1988) (99)
- A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome. (1991) (99)
- Thrombospondin 3 (Thbs3), a new member of the thrombospondin gene family. (1992) (97)
- Thrombospondin-4 Regulates Vascular Inflammation and Atherogenesis (2010) (97)
- Thrombospondin 2 modulates collagen fibrillogenesis and angiogenesis. (2000) (96)
- Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy (2009) (96)
- The Limited Cleavage of Native Collagen with Chymotrypsin, Trypsin, and Cyanogen Bromide (1966) (95)
- Amniotic fluid fibronectin. Characterization and synthesis by cells in culture (1978) (95)
- Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. (2008) (94)
- Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane (1999) (93)
- Structural basis for apparent heterogeneity of collagens in human basement membranes: type IV procollagen contains two distinct chains. (1980) (93)
- Biochemical and ultrastructural studies of proteoheparan sulfates synthesized by PYS-2, a basement membrane-producing cell line (1982) (92)
- Altered secretion of type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts. (1981) (92)
- Heparin regulates the collagen phenotype of vascular smooth muscle cells: induced synthesis of an Mr 60,000 collagen (1985) (92)
- The specific nonenzymatic cleavage of bovine ribonuclease with hydroxylamine. (1970) (92)
- Increased Marrow‐Derived Osteoprogenitor Cells and Endosteal Bone Formation in Mice Lacking Thrombospondin 2 (2000) (89)
- Biosynthetic and structural properties of endothelial cell type VIII collagen. (1983) (89)
- Heparin and related glycosaminoglycans modulate the secretory phenotype of vascular smooth muscle cells (1984) (87)
- Cleavage at Asn-Gly bonds with hydroxylamine. (1977) (87)
- Expression of thrombospondins by endothelial cells. Injury is correlated with TSP-1. (1995) (87)
- THE ELASTIC FIBER (1969) (86)
- The first intron of the alpha 1(I) collagen gene contains several transcriptional regulatory elements. (1988) (86)
- Glycosylation Mediates Up-regulation of a Potent Antiangiogenic and Proatherogenic Protein, Thrombospondin-1, by Glucose in Vascular Smooth Muscle Cells* (2007) (84)
- Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo. (1995) (84)
- Design of “Smart” polymers that can direct intracellular drug delivery (2002) (84)
- Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. (2002) (82)
- Collagen synthesis by human amniotic fluid cells in culture: characterization of a procollagen with three identical proalpha1(I) chains. (1978) (82)
- Coordinate transcriptional regulation of type I procollagen genes by Rous sarcoma virus. (1981) (81)
- Location of a collagen-binding domain in fibronectin. (1980) (81)
- Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen. (2008) (80)
- A serum response element and a binding site for NF-Y mediate the serum response of the human thrombospondin 1 gene. (1993) (79)
- Overlapping Egr-1 and Sp1 sites function in the regulation of transcription of the mouse thrombospondin 1 gene. (1994) (79)
- Elastic fibers in the body. (1971) (77)
- A presumptive subunit of elastic fiber microfibrils secreted by arterial smooth-muscle cells in culture. (1976) (76)
- Characterization of a type IV procollagen synthesized by human amniotic fluid cells in culture. (1979) (75)
- Interchain disulfide bonds in procollagen are located in a large nontriple-helical COOH-terminal domain. (1975) (75)
- An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice (1991) (75)
- Type VIII collagen from bovine Descemet's membrane: structural characterization of a triple-helical domain. (1986) (73)
- Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells. (2007) (71)
- Location of procollagen in chick corneal and tendon fibroblasts with ferritin-conjugated antibodies (1975) (71)
- Oncogenes and Angiogenesis: down-regulation of thrombospondin-1 in normal fibroblasts exposed to factors from cancer cells harboring mutant ras. (2005) (69)
- The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun (1999) (68)
- The Secreted Protein Thrombospondin 2 Is an Autocrine Inhibitor of Marrow Stromal Cell Proliferation (2002) (68)
- Structure of rat skin collagen alpha 1-CBB. Amino acid sequence of the hydroxyl amine-produced fragment HA2. (1971) (67)
- Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials. (2003) (67)
- Cell-specific expression of alpha 1(I) collagen-hGH minigenes in transgenic mice (1994) (67)
- Thrombospondin 2 levels are increased in aged mice: consequences for cutaneous wound healing and angiogenesis. (2004) (66)
- Regulation of protein synthesis: translational control by procollagen-derived fragments. (1981) (65)
- Mice With a Deletion in the First Intron of the Col1a1 Gene Develop Age-Dependent Aortic Dissection and Rupture (2004) (64)
- Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice. (2005) (62)
- Isolation and characterization of the cyanogen bromide peptides from the alpha 1 and alpha 2 chains of human skin collagen. (1970) (62)
- Procollagen: Conversion of the Precursor to Collagen by a Neutral Protease (1972) (62)
- Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease. (1995) (61)
- Regulation of angiogenesis and matrix remodeling by localized, matrix-mediated antisense gene delivery. (2001) (60)
- Mice with a Disruption of the Thrombospondin 3 Gene Differ in Geometric and Biomechanical Properties of Bone and Have Accelerated Development of the Femoral Head (2005) (60)
- Regulation of collagen I gene expression by ras (1992) (60)
- Biosynthesis of an unusual collagen type by human astrocytoma cells in vitro. (1983) (59)
- Comparative sequence studies of rat skin and tendon collagen. II. The absence of a short sequence at the amino terminus of the skin alpha-1 chain. (1969) (59)
- Characterization of the pro- 1 chain of procollagen. (1972) (58)
- Do hyperplastoid cell lines "differentiate themselves to death"? (1975) (58)
- Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina. (2009) (56)
- Type VIII collagen. Synthesis by normal and malignant cells in culture. (1984) (56)
- Intermediates in the limited proteolytic conversion of procollagen to collagen. (1975) (55)
- Characterization of cell matrix associated collagens synthesized by aortic endothelial cells in culture. (1981) (55)
- Two different cis-acting regulatory regions direct cell-specific transcription of the collagen alpha 1(I) gene in hepatic stellate cells and in skin and tendon fibroblasts. (1995) (53)
- Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1. (1994) (53)
- A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum. (1991) (53)
- A highly conserved intronic sequence is involved in transcriptional regulation of the alpha 1(I) collagen gene. (1990) (52)
- A Gene-Targeting Approach Identifies a Function for the First Intron in Expression of the α1(I) Collagen Gene (1998) (52)
- Endothelial Cells from Umbilical Vein and a Hemangioendothelioma Secrete Basement Membrane Largely to the Exclusion of Interstitial Procollagens (1982) (51)
- Further hydroxylation of lysyl residues in collagen by protocollagen lysyl hydroxylase in vitro. (1973) (51)
- Characterization of the precursor form of type VI collagen. (1984) (51)
- Transcriptional activity of the alpha 1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro. (1991) (51)
- Enhanced Angiogenesis and Reduced Contraction in Thrombospondin-2–null Wounds Is Associated With Increased Levels of Matrix Metalloproteinases-2 and −9, and Soluble VEGF (2009) (51)
- Susceptibility of type V collagen to neutral proteases: evidence that the major molecular species is a thrombin-sensitive heteropolymer, [alpha 1(V)]2 alpha 2(V). (1981) (50)
- Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model. (2005) (49)
- Correlation of collagen synthesis and procollagen messenger RNA levels with transformation in rat embryo fibroblasts. (1981) (49)
- Heterogeneity of the α Chains of Rat Skin Collagen and Its Relation to the Biosynthesis of Cross-Links* (1966) (49)
- Structure and organization of the human metaxin gene (MTX) and pseudogene. (1996) (48)
- Megakaryocytes require thrombospondin-2 for normal platelet formation and function. (2003) (48)
- Partial amino acid sequence of human thrombospondin as determined by analysis of cDNA clones: homology to malarial circumsporozoite proteins. (1986) (47)
- Partial purification and characterization of phosphotyrosyl-protein phosphatase from Ehrlich ascites tumor cells. (1982) (46)
- Interactions between CD47 and Thrombospondin Reduce Inflammation (2007) (45)
- THE DISTRIBUTION OF ANTIGENIC DETERMINANTS IN RAT SKIN COLLAGEN (1971) (45)
- Regulation of expression of the α 1 (1) collagen gene: A critical appraisal of the role of the first intron (1996) (44)
- Renal function during extracorporeal circulation at high and low flow rates: experimental studies in dogs. (1960) (44)
- Preparation and characterization of procollagens and procollagen-collagen intermediates. (1982) (43)
- Biosynthesis of type V procollagen by A204, a human rhabdomyosarcoma cell line. (1982) (43)
- Characterization of the mouse thrombospondin gene and evaluation of the role of the first intron in human gene expression. (1990) (43)
- Location and partial characterization of the heparin-binding fragment of platelet thrombospondin. (1984) (42)
- Intermediates in the conversion of procollagen to collagen. Evidence for stepwise limited proteolysis of the COOH-terminal peptide extensions. (1977) (41)
- Inhibitory effects of glucocorticoids on collagen synthesis by mouse sponge granulomas and granuloma fibroblasts in culture. (1978) (40)
- Cell surface morphology and adhesive properties of normal and virally transformed cells treated with tunicamycin, an inhibitor of protein glycosylation. (1978) (40)
- Synthesis and Secretion of Structural Macromolecules by Endothelial Cells in Culture (1982) (40)
- Mice lacking thrombospondin 2 show an atypical pattern of endocortical and periosteal bone formation in response to mechanical loading. (2006) (39)
- Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: Induction by basic fibroblast growth factor (1990) (38)
- Structural analysis and expression of the human thrombospondin gene promoter. (1988) (38)
- The nature of a hydroxylamine-sensitive bond in collagen. (1969) (38)
- Collagen: Structural Studies Based on the Cleavage of Methionyl Bonds (1965) (38)
- Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in experimental glomerulonephritis in mice. (2007) (37)
- Thrombospondin 2 Deficiency in Pregnant Mice Results in Premature Softening of the Uterine Cervix1 (2004) (36)
- Characterization of procollagen-derived peptides unique to the precursor molecule. (1975) (36)
- The incomplete hydroxylation of individual prolyl residues in collagen. (1967) (35)
- Declining procollagen mRNA sequences in chick embryo fibroblasts infected with rous sarcoma virus. Correlation with procollagen synthesis. (1979) (35)
- Feedback regulation of collagen gene expression: a Trojan horse approach. (1991) (35)
- The metabolic requirements for transcellular movement and secretion of collagen. (1975) (35)
- An X-linked form of cutis laxa due to deficiency of lysyl oxidase. (1976) (35)
- Effects of antimicrotubular agents on glycosaminoglycan synthesis and secretion by embryonic chick cartilage and chondrocytes. (1974) (35)
- NH2-terminal sequence of the chick proalpha1(I) chain synthesized in the reticulocyte lysate system. Evidence for a transient hydrophobic leader sequence. (1979) (35)
- The NH(2)-terminal propeptides of fibrillar collagens: highly conserved domains with poorly understood functions. (2002) (34)
- Characterization of a type VI collagen-related Mr-140 000 protein from cutis-laxa fibroblasts in culture. (1985) (33)
- Structure and organization of the human thrombospondin 3 gene (THBS3). (1995) (33)
- Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene (THBS2). (1997) (33)
- SPARC-thrombospondin-2-double-null Mice Exhibit Enhanced Cutaneous Wound Healing and Increased Fibrovascular Invasion of Subcutaneous Polyvinyl Alcohol Sponges (2005) (33)
- The comparative biochemistry of collagen: the structure of rabbit skin colllagen and its relevance to immunochemical studies of collagen. (1970) (32)
- The role of glycosylation in the enzymatic conversion of procollagen to collagen: studies using tunicamycin and concanavalin A. (1978) (30)
- Characterization of the pro 1 chain of procollagen. Isolation of a sequence unique to the precursor chain. (1973) (30)
- A STUDY OF RABBIT γ-GLOBULIN ALLOTYPY BY MEANS OF HETEROIMMUNIZATIONS (1964) (30)
- Further characterization of procollagen. Purification and analysis of the pro.alpha.1 chain of chick bone procollagen (1975) (29)
- Tyrosylprotein kinase and phosphatase activities in membrane vesicles from normal and Rous sarcoma virus-transformed rat cells. (1981) (29)
- Mapping of the thrombospondin gene to human chromosome 15 and mouse chromosome 2 by in situ hybridization. (1990) (28)
- Lack of thrombospondin-2 reduces fibrosis and increases vascularity around cardiac cell grafts. (2013) (28)
- Cell-matrix interactions: the view from the outside. (2002) (28)
- Isolation and characterization of the mouse thrombospondin 3 (Thbs3) gene. (1993) (28)
- The NH2-terminal Propeptide of Type I Procollagen Acts Intracellularly to Modulate Cell Function* (2006) (27)
- Comparison of the structures of human fibronectin and plasma cold-insoluble globulin. (1979) (25)
- Serratia marcescens cellulitis in a patient on hemodialysis. (1992) (25)
- Modulation of thrombospondin gene expression during osteoblast differentiation in MC3T3-E1 cells. (1992) (25)
- The immunology of procollagen. I. Development of antibodies to determinants unique to the proalpha l chain. (1973) (25)
- Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells (1994) (24)
- Metaxin deficiency alters mitochondrialmembrane permeability and leads to resistance to TNF-induced cell killing (2010) (23)
- Elements in the first intron of the alpha 1(I) collagen gene interact with Sp1 to regulate gene expression. (1992) (23)
- Matricellular proteins: an overview. (2000) (23)
- Collagen: Relatively Invariant (Helical) and Variable (Nonhelical) Regions (1968) (23)
- Restoration of thrombospondin 1 expression in tumor cells harbouring mutant ras oncogene by treatment with low doses of doxycycline. (2003) (22)
- Characterization of the mouse thrombospondin 2 gene. (1993) (22)
- Intermolecular Cross-Linking of Collagen and the Identification of a New Beta-Component (1964) (21)
- Homology between the 1 and 2 chains of collagen. (1972) (21)
- Increased osteoblastogenesis and decreased bone resorption protect against ovariectomy-induced bone loss in thrombospondin-2-null mice. (2005) (21)
- Highly conserved sequences in the 3′‐untranslated region of the COL1A1 gene bind cell‐specific nuclear proteins (1991) (20)
- A new mapping technique for collagen chains. (1980) (20)
- Endothelial cells secrete a novel collagen type in vitro independently of prolyl hydroxylation. (1982) (20)
- Effects of Zn2+ ions on protein phosphorylation in epithelial cell membranes (1983) (20)
- Reduced Expression of Thrombospondins and Craniofacial Dysmorphism in Mice Overexpressing Fra1 (2005) (20)
- Transcriptional repression of the α1(I) collagen gene by ras is mediated in part by an intronic AP1 site (1995) (20)
- Preliminary Studies on Mechanochemical-structure Relationships in Connective Tissues Using Enzymolysis Techniques (1973) (19)
- Cyanogen bromide cleavage of guinea pig skin collagen. Isolation and characterization of peptides from the 1 and 2 chains. (1972) (19)
- Fetal calf ligament fibroblasts in culture secrete a low molecular weight collagen with a unique resistance to proteolytic degradation (1983) (17)
- The Globular Domain of the Proα1(I) N-Propeptide Is Not Required for Secretion, Processing by Procollagen N-Proteinase, or Fibrillogenesis of Type I Collagen in Mice* (2002) (17)
- Continuous recording in vivo of respiratory air oxygen tension. (1960) (17)
- A highly conserved, 5' untranslated, inverted repeat sequence is ineffective in translational control of the alpha 1(I) collagen gene. (1988) (17)
- Further characterization of procollagen: the identification of a pro- 2 chain. (1972) (17)
- Transcriptional control of the alpha 1(I) collagen gene involves orientation- and position-specific intronic sequences. (1990) (17)
- In vitro enzymatic hydroxylation of prolyl residues in the alpha 1-CB2 fragment of rat collagen. (1971) (17)
- Regulation of expression of the alpha 1 (I) collagen gene: a critical appraisal of the role of the first intron. (1996) (16)
- Structural and functional analysis of the first intron of the human α2(I) collagen-encoding gene (1990) (15)
- Mice with a deletion in the first intron of the Col1a1 gene develop dissection and rupture of aorta in the absence of aneurysms: High‐resolution magnetic resonance imaging, at 4.7 T, of the aorta and cerebral arteries (2006) (15)
- Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration. (2015) (14)
- Bioinspired polymers that control intracellular drug delivery (2001) (14)
- Regulation of type I collagen mRNA levels in fibroblasts. (1986) (14)
- Regulation of growth and gene activity in euploid hybrids between human neonatal fibroblasts and epithelioid amniotic fluid cells. (1978) (14)
- SP1-binding elements, within the common metaxin-thrombospondin 3 intergenic region, participate in the regulation of the metaxin gene. (1996) (13)
- DNA synthesis of sublethally injured cells in heterokaryons and its relevance to clonal senescence. (1979) (13)
- Disorders of connective tissue function and the aging process: A synthesis and review of current concepts and findings (1976) (12)
- Thrombospondin: A Multifunctional Platelet and Extracellular Matrix Glycoprotein (1987) (12)
- Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar disc (2008) (11)
- Platelet MAO-B and endogenous MAO-a inhibitory activity in depressed patients: Stability with electroconvulsive treatment (1987) (11)
- Procollagen processing. Limited proteolysis of COOH-terminal extension peptides by a cathepsin-like protease secreted by tendon fibroblasts. (1979) (11)
- AMNIOTIC FLUID FIBRONECTIN AND THE SYNTHESIS OF FIBRONECTIN BY AMNIOTIC FLUID CELLS IN CULTURE (1978) (10)
- Covalent cross-links in collagen: a personal account of their discovery. (2003) (10)
- Evidence forProcollagen, aBiosynthetic Precursor ofCollagen (1971) (10)
- The structure and assembly of procollagen - a review. (1974) (10)
- Inhibition of protein synthesis in vitro by procollagen-derived fragments is associated with changes in protein phosphorylation. (1982) (10)
- Mice with a targeted intronic deletion in the Col1a1 gene respond to bleomycin-induced pulmonary fibrosis with increased expression of the mutant allele. (1999) (10)
- The human thrombospondin 3 gene: analysis of transcription initiation and an alternatively spliced transcript. (1999) (9)
- The order of cyanogen-bromide peptides and location of carbohydrate in the alpha2 chain of guinea-pig skin collagen. (1975) (9)
- Expression in SPARC-null mice of collagen type I lacking the globular domain of the α1(I) N-propeptide results in abdominal hernias and loss of dermal collagen. (2010) (8)
- Extracellular MMP2 levels are regulated by the LRP scavenger recept thrombospondin 2. (2000) (8)
- Electron microscopy as an aid to diagnosis of disorders of the extracellular matrix: a new type of spondyloepiphyseal dysplasia. (1978) (7)
- Cross-linking of collagen chains. (1966) (7)
- Comparative studies on the chemistry of collagen utilizing cyanogen bromide cleavage. (1968) (7)
- A tightly organized, conserved gene cluster on mouse Chromosome 3 (E3-F1) (1995) (7)
- Regulation of Collagen Biosynthesis (1985) (7)
- Regulation of collagen synthesis. (1984) (6)
- Faculty Opinions recommendation of Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. (2006) (6)
- A new variety of spondyloepiphyseal dysplasia characterized by punctate corneal dystrophy and abnormal dermal collagen fibrils (1978) (5)
- Corrigendum to “The role of Thrombospondins 1 and 2 in the regulation of cell–matrix interaction, collagen fibril formation and the response to injury” (2005) (5)
- Regulatory elements in the first intron contribute to transcriptional control of the human al ( I ) collagen gene ( DNA sequence / transcription factors / promoter ) (2003) (4)
- Erratum to: Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing (2010) (4)
- Structural and functional analysis of the first intron of the human alpha 2(I) collagen-encoding gene. (1990) (3)
- Bioinspired Engineering of Intelligent Drug Delivery Systems and Protein– Polymer Conjugates (2002) (2)
- Targeted disruption of a novel gene contiguous to both glucocerebrodisidase (GC) and thrombospondin 3 (TSP3), results in an embryonic lethal phenotype in the mouse (1994) (2)
- The First Intron of the d ( 1 ) Collagen Gene Contains Several Transcriptional Regulatory Elements* (2001) (2)
- American Academy of Orthopaedic Surgeons Symposium on Heritable Disorders of Connective Tissue, San Diego, California, May 1980 (1982) (2)
- The organization of extracellular proteins on the connective tissue cell surface. (1977) (1)
- THE STRUCTURE, SYNTHESIS, AND SECRETION OF PRO-COLLAGEN (1975) (1)
- Heritable Disorders of Connective Tissue (1984) (1)
- Elements in the first intron of the a l( l) collagen gene interact with Spl to regulate gene expression (2016) (1)
- BIOCHIMICAet BIOPHYSICA ACTA BIOMEMBRANES INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS REVUE INTERNATIONALE DE BIOCHIMIE ET BIOPHYSIQUE INTERNATIONALE ZEITSCHRIFT FÜR BIOCHEMIE UND BIOPHYSIK EDITORIAL BOARD (1977) (1)
- TO TISSUE ENGINEER HEART MUSCLE (2003) (1)
- Structure of rat skin collagen 1-CB8. Amino acid sequence of the hydroxylamine-produced fragment HA1. (1971) (1)
- The human thrombospondin 3 gene (1999) (1)
- Thrombospondins: Endogenous Inhibitors of Angiogenesis (2008) (1)
- Fifth International Workshop on the CCN Family of Genes: Abstracts and Posters October 18–22, 2008 (2008) (1)
- Faculty Opinions recommendation of CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1. (2006) (0)
- Faculty Opinions recommendation of Lysyl oxidase interacts with hormone placental lactogen and synergistically promotes breast epithelial cell proliferation and migration. (2007) (0)
- Chapter 13 Thrombospondins : Endogenous Inhibitors of Angiogenesis (0)
- Skeletal abnormalities in quad-KO mice (TSP1, 3, 5, and Col 9) (2008) (0)
- siRNA-Mediated Inhibition of Thrombospondin 2 Gene Expression (2008) (0)
- Karl A. Piez (1924–2006): a personal tribute (Guest Editorial) (2006) (0)
- A STUDY OF RABBIT 7-GLOBULIN ALLOTYPY BY MEANS OF I-rETEROIMMUNIZATIONS* (2003) (0)
- Evidence for Procollagen , a Biosynthetic Precursor of Collagen ( zymogen / pepsin digestion / chromatography / gel electrophore 3 is / isotopic labeling ) (0)
- Sulfated Roteoglycans Synthesized by Vascular Endothelial Cells in Culture* (2001) (0)
- EXTRACELLULAR MATRIX | Matricellular Proteins (2006) (0)
- Isolation and Characterization of a Glycoprotein Secreted Endothelial Cells in Culture APPARENT IDENTITY WITH PLATELET THROMBOSPONDIN * by Aortic (2001) (0)
- With Increased Levels of Matrix Metalloproteinases-2 and null Wounds Is Associated − Enhanced Angiogenesis and Reduced Contraction in Thrombospondin-2 (2009) (0)
- The N_propeptide of type I procollagen functions intracellularly (2006) (0)
- Editorial Board (2010) (0)
- Faculty Opinions recommendation of Autocrine VEGF signaling is required for vascular homeostasis. (2007) (0)
- Discovery of Chemical Nature of Cross-Links in Collagen: A Personal Retrospective (2009) (0)
- MMP2-DEPENDENT PROTEOLYSIS OF EXTRACELLULAR MATRICES IN THROMBOSPONDIN 2-NULL MICE CONTRIBUTES TO A BLEEDING DIATHESIS (2004) (0)
- [THE USE OF IMMUNE SERUMS FROM ANIMALS OF SPECIES OTHER THAN THE RABBIT FOR THE STUDY OF THE ALLOTYPE OF RABBIT GAMMA GLOBULINS]. (1964) (0)
- Progress toward engineered biomaterials that heal (2004) (0)
- THE BIOSYNTHESIS OF COLLAGEN 858 (1974) (0)
- A comparison of major depression, ECT, and mild AD on episodic memory (2000) (0)
- In Vitro Enzymatic Hydroxylation of Prolyl Residues in the al & B 2 Fragment of Rat Collagen * (2005) (0)
- Interactions between thePromoter andFirst Intron AreInvolved in Transcriptional Control ofal(I) Collagen GeneExpression (1988) (0)
- Phosphot ~ osyl-protein Phosphatase SPECIFIC INHIBITION (2001) (0)
- Regulation ofGrowthandGeneActivity inEuploid Hybrids between HumanNeonatal Fibroblasts andEpithelioid Amniotic Fluid Cells (1978) (0)
- The Distribution of Antigenic Determinants in Collagen as Determined by a Radioimmunoassay (1974) (0)
- Cell-specific Expression of.l(I) Collagen-hGH Minigenes in Transgenic Mice (2002) (0)
- Mouse thrombospondin 3 and metaxin share a common promoter region but are regulated by separate cis-acting elements (1997) (0)
- Low-Density Lipoprotein Receptor-Related Protein Contributes to the Antiangiogenic Activity of Thrombospondin-2 in a (2005) (0)
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