Peter Claus Heinrich
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Molecular Biology
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Biochemistry
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Biology
Peter Claus Heinrich's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Molecular Biology Stanford University
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(Suggest an Edit or Addition)Peter Claus Heinrich's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Principles of interleukin (IL)-6-type cytokine signalling and its regulation. (2003) (3115)
- Interleukin-6 and the acute phase response. (1990) (2717)
- Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. (1998) (2167)
- Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes (1989) (843)
- Soluble receptors for cytokines and growth factors: generation and biological function. (1994) (765)
- Acute‐phase response of human hepatocytes: Regulation of acute‐phase protein synthesis by interleukin‐6 (1990) (758)
- Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level (1993) (547)
- The soluble interleukin‐6 receptor is generated by shedding (1993) (499)
- A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6. (1995) (442)
- Recombinant human interleukin‐6 (IL‐6/BSF‐2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes (1988) (442)
- SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130* (2000) (438)
- Induction of rat acute‐phase proteins by interleukin 6 in vivo (1988) (393)
- Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins. (1992) (379)
- Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3 1 (2003) (353)
- Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 (1996) (339)
- Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. (2006) (336)
- IFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3 (2003) (334)
- Hepatic acute phase proteins--regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling. (2012) (315)
- Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat. (1988) (305)
- The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site. (1994) (280)
- Recombinant human B cell stimulatory factor 2 (BSF‐2/IFN‐β2) regulates β‐fibrinogen and albumin mRNA levels in Fao‐9 cells (1987) (273)
- The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family (1994) (259)
- SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130* (2003) (256)
- Action of recombinant human interleukin 6, interleukin 1β and tumor necrosis factor α on the mRNA induction of acute‐phase proteins (1988) (238)
- LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages (1999) (223)
- STAT3 is constitutively activated in Hodgkin cell lines. (2001) (219)
- Control of proteolysis. (1980) (218)
- Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression. (1998) (214)
- Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 (1996) (200)
- Urokinase Receptor Is Associated with the Components of the JAK1/STAT1 Signaling Pathway and Leads to Activation of This Pathway upon Receptor Clustering in the Human Kidney Epithelial Tumor Cell Line TCL-598* (1997) (181)
- The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements (1994) (180)
- Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. (1998) (177)
- Regulation of synthesis and secretion of major rat acute-phase proteins by recombinant human interleukin-6 (BSF-2/IL-6) in hepatocyte primary cultures. (1988) (174)
- A Di-leucine Motif and an Upstream Serine in the Interleukin-6 (IL-6) Signal Transducer gp130 Mediate Ligand-induced Endocytosis and Down-regulation of the IL-6 Receptor (*) (1996) (173)
- Hepatic cytochrome P450 down‐regulation during aseptic inflammation in the mouse is interleukin 6 dependent (2000) (168)
- Soluble interleukin‐6 (IL‐6) receptor augments central effects of IL‐6 in vivo (1995) (158)
- Expression of suppressors of cytokine signaling during liver regeneration. (2001) (157)
- Real Time Analysis of STAT3 Nucleocytoplasmic Shuttling* (2004) (151)
- Different protein turnover of interleukin-6-type cytokine signalling components. (1999) (146)
- Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1 (1999) (142)
- UVA-induced autocrine stimulation of fibroblast-derived-collagenase by IL-6: a possible mechanism in dermal photodamage? (1993) (142)
- Interleukin-6. The major regulator of acute-phase protein synthesis in man and rat. (2008) (142)
- Tyrosine Phosphorylation Disrupts Elongin Interaction and Accelerates SOCS3 Degradation* (2003) (141)
- The hepatic interleukin‐6 receptor Down‐regulation of the interleukin‐6 binding subunit (gp80) by its ligand (1992) (135)
- Mutational analysis of acute-phase response factor/Stat3 activation and dimerization (1997) (133)
- Oncostatin M and the Interleukin-6 and Soluble Interleukin-6 Receptor Complex Regulate α1-Antichymotrypsin Expression in Human Cortical Astrocytes* (1998) (128)
- Differential shedding of the two subunits of the interleukin‐6 receptor (1993) (125)
- Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma. (2003) (125)
- Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor. (1992) (122)
- Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter. (1995) (119)
- Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38MAPK/MK2 Cascade1 (2007) (116)
- The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity* (1999) (113)
- Janus Kinase (Jak) Subcellular Localization Revisited (2004) (107)
- Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. (1993) (106)
- Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers. (2002) (104)
- Interleukin‐6 is a direct mediator of T cell migration (2004) (103)
- Interleukin-6 regulates hepatic transporters during acute-phase response. (2004) (103)
- Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction1 (2002) (102)
- The Cytoplasmic Tyrosine Motifs in Full-Length Glycoprotein 130 Have Different Roles in IL-6 Signal Transduction1 (2000) (102)
- Development of a human interleukin-6 receptor antagonist. (1994) (99)
- Studies on the structure and regulation of the human hepatic interleukin-6 receptor. (1990) (99)
- Inhibition of gp130 Signaling in Breast Cancer Blocks Constitutive Activation of Stat3 and Inhibits in Vivo Malignancy (2004) (99)
- A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor. (2002) (98)
- Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis. (1999) (98)
- A possible role for soluble IL-6 receptor in the pathogenesis of systemic onset juvenile chronic arthritis. (1998) (97)
- Nucleocytoplasmic shuttling of persistently activated STAT3 (2007) (95)
- Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression* (2002) (95)
- The Jak1 SH2 Domain Does Not Fulfill a Classical SH2 Function in Jak/STAT Signaling but Plays a Structural Role for Receptor Interaction and Up-regulation of Receptor Surface Expression* (2005) (94)
- Regulation of tissue inhibitor of metalloproteinases‐1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures (1993) (93)
- Structure‐function analysis of human interleukin‐6 (1990) (92)
- Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation (2010) (92)
- Activation of bone marrow‐derived mouse macrophages by bacterial lipopeptide: cytokine production, phagocytosis and Ia expression (1990) (89)
- Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor. (1994) (88)
- Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells (2005) (88)
- Interleukin‐6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti‐gp130 monoclonal antibodies (1995) (88)
- Interleukin‐6‐induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin‐6 target gene induction (1995) (88)
- The Inhibition of Interleukin-6-dependent STAT Activation by Mitogen-activated Protein Kinases Depends on Tyrosine 759 in the Cytoplasmic Tail of Glycoprotein 130* (2000) (87)
- Transforming Growth Factor β1 Regulates Tissue Inhibitor of Metalloproteinases—1 Expression in Differentiated Human Articular Chondrocytes (1994) (86)
- Activation of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway by Osmotic Shock* (1998) (85)
- 1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes. (1983) (84)
- Akt Modulates STAT3-mediated Gene Expression through a FKHR (FOXO1a)-dependent Mechanism* (2003) (83)
- Non-redundant Signal Transduction of Interleukin-6-type Cytokines (2000) (83)
- Ciliary neurotrophic factor induces acute‐phase protein expression in hepatocytes (1992) (83)
- Characterization of the Signaling Capacities of the Novel gp130-like Cytokine Receptor* (2004) (82)
- Interferon-gamma-mediated growth regulation of melanoma cells: involvement of STAT1-dependent and STAT1-independent signals. (2004) (82)
- Time course of various inflammatory mediators during recurrent endotoxemia. (1992) (82)
- Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions. (1998) (82)
- Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes. (1999) (81)
- Cytoplasmic STAT proteins associate prior to activation. (2000) (80)
- Effect of swainsonine on the processing of the asparagine-linked carbohydrate chains of alpha 1-antitrypsin in rat hepatocytes. Evidence for the formation of hybrid oligosaccharides. (1983) (78)
- Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing. (1996) (78)
- Studies on the reconstitution of apotransketolase with thiamine pyrophosphate and analogs of the coenzyme. (1972) (78)
- Molecular cloning of cDNA sequences for rat alpha 2-macroglobulin and measurement of its transcription during experimental inflammation. (1985) (77)
- The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling. (2004) (75)
- TIMP expression in toxic and cholestatic liver injury in rat. (1997) (75)
- Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells. (2001) (74)
- Up‐regulation of the interleukin‐6‐signal transducing protein (gp130) by interleukin‐6 and dexamethasone in HepG2 cells (1992) (74)
- JAKs, STATs and signal transduction in response to the interferons and other cytokines. (1996) (73)
- Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts. (2005) (73)
- Mapping of a Region within the N Terminus of Jak1 Involved in Cytokine Receptor Interaction* (2001) (73)
- Molecular Modeling-guided Mutagenesis of the Extracellular Part of gp130 Leads to the Identification of Contact Sites in the Interleukin-6 (IL-6)·IL-6 receptor·gp130 Complex* (1997) (73)
- Disturbed immuno-endocrine communication via the hypothalamo-pituitary-adrenal axis in autoimmune disease. (1993) (71)
- Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver. (1976) (71)
- Induction of rat α2‐macroglobulin in vivo and in hepatocyte primary cultures: synergistic action of glucocorticoids and a Kupffer cell‐derived factor (1984) (71)
- Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells* (2004) (70)
- Interleukin‐1β induces synthesis and secretion of interleukin‐6 in human chondrocytes (1990) (69)
- Fate and biological action of human recombinant interleukin 1β in the rat in vivo (1989) (69)
- Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130. (1999) (69)
- Identification of the promoter sequences involved in the interleukin-6 dependent expression of the rat alpha 2-macroglobulin gene. (1989) (68)
- STAT5 Contributes to Interferon Resistance of Melanoma Cells (2005) (68)
- Oncostatin M differentially regulates tissue inhibitors of metalloproteinases TIMP-1 and TIMP-3 gene expression in human synovial lining cells. (1996) (68)
- Importance of the Membrane-Proximal Extracellular Domains for Activation of the Signal Transducer Glycoprotein 1301 (2000) (68)
- Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway. (1998) (67)
- The three carboxy‐terminal amino acids of human interleukin‐6 are essential for its biological activity (1990) (67)
- Are STATS Arginine-methylated?* (2005) (66)
- Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification. (1993) (65)
- STAT3 is enriched in nuclear bodies (2004) (64)
- Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation. (2002) (62)
- Interleukin-6 and related cytokines: effect on the acute phase reaction. (1998) (62)
- The biosynthesis of acute-phase proteins in primary cultures of rat hepatocytes. (1983) (62)
- Synthesis of tissue inhibitor of metalloproteinase‐1 (TIMP‐1) in human hepatoma cells (HepG2) Up‐regulation by interleukin‐6 and transforming growth factor β1 (1992) (61)
- Interleukin‐27 displays interferon‐γ–like functions in human hepatoma cells and hepatocytes (2009) (59)
- Dual Role of the Jak1 FERM and Kinase Domains in Cytokine Receptor Binding and in Stimulation-Dependent Jak Activation1 (2008) (58)
- Characterization and Binding Specificity of the Monomeric STAT3-SH2 Domain* (1999) (58)
- Cell Density–Dependent Increase of Constitutive Signal Transducers and Activators of Transcription 3 Activity in Melanoma Cells Is Mediated by Janus Kinases (2007) (56)
- Signal Transduction of IL-6, Leukemia-Inhibitory Factor, and Oncostatin M: Structural Receptor Requirements for Signal Attenuation1 (2000) (56)
- O‐ and N‐glycosylation lead to different molecular mass forms of human monocyte interleukin‐6 (1989) (56)
- Long Term Association of the Cytokine Receptor gp130 and the Janus Kinase Jak1 Revealed by FRAP Analysis* (2003) (56)
- Murine interleukin 1 stimulates α2‐macroglobulin synthesis in rat hepatocyte primary cultures (1985) (55)
- Soluble interleukin 6 receptor is biologically active in vivo. (1995) (55)
- Hepatocyte growth factor/scatter factor (HGF/SF) signals via the STAT3/APRF transcription factor in human hepatoma cells and hepatocytes (1997) (55)
- Mammary Gland Remodeling Depends on gp130 Signaling through Stat3 and MAPK* (2004) (54)
- Constitutive Suppressor of Cytokine Signaling 3 Expression Confers a Growth Advantage to a Human Melanoma Cell Line (2007) (54)
- Orientational Constraints of the gp130 Intracellular Juxtamembrane Domain for Signaling* (2002) (54)
- Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation. (2005) (54)
- Biosynthesis and half-life of the interleukin-6 receptor and its signal transducer gp130. (1994) (53)
- Induction of acute phase proteins by dexamethasone in rat hepatocyte primary cultures. (1984) (52)
- Constitutive internalization and association with adaptor protein‐2 of the interleukin‐6 signal transducer gp130 (1998) (52)
- TNF-α Induces Tyrosine Phosphorylation and Recruitment of the Src Homology Protein-Tyrosine Phosphatase 2 to the gp130 Signal-Transducing Subunit of the IL-6 Receptor Complex 1 (2003) (52)
- Operation of pleiotropic control in hormonal regulation and in neoplasia. (1974) (51)
- Time course of IL-6 and TNFα release during endotoxin-induced endotoxin tolerance in rats (1991) (50)
- Interleukin‐6‐Type Cytokines and Their Receptors for Gene Therapy of Melanoma a (1995) (50)
- Evidence for the importance of a positive charge and an α‐helical structure of the C‐terminus for biological activity of human IL‐6 (1991) (50)
- The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL‐6 and the IL‐6 receptor (1995) (49)
- The Inhibitory Effect of IL-1β on IL-6-Induced α2-Macroglobulin Expression Is Due to Activation of NF-κB1 (2001) (48)
- A fusion protein of interleukin‐11 and soluble interleukin‐11 receptor acts as a superagonist on cells expressing gp130 (1999) (48)
- Structure and acute-phase regulation of the rat alpha 2-macroglobulin gene. (1988) (48)
- Interleukin-6 in autoimmune disease. Role of IL-6 in physiology and pathology of the immune defense. (1993) (48)
- Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells. (1991) (48)
- A Fusion Protein of the gp130 and Interleukin-6Rα Ligand-binding Domains Acts as a Potent Interleukin-6 Inhibitor* (2003) (48)
- Fate of interleukin-6 in the rat. Involvement of skin in its catabolism. (1990) (47)
- The acute-phase induction of alpha 2-macroglobulin in rat hepatocyte primary cultures: action of a hepatocyte-stimulating factor, triiodothyronine and dexamethasone. (1986) (45)
- Soluble receptors for cytokines and growth factors. (1996) (45)
- Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation (1996) (45)
- Structural and functional studies on the human interleukin-6 receptor. Binding, cross-linking, internalization, and degradation of interleukin-6 by fibroblasts transfected with human interleukin-6-receptor cDNA. (1991) (45)
- Interleukin-11 expression: its significance in eutopic and ectopic human implantation. (2004) (45)
- In vitro synthesis of peroxisomal membrane polypeptides. (1986) (45)
- Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-beta 2) regulates beta-fibrinogen and albumin mRNA levels in Fao-9 cells. (1987) (45)
- The Chemoattractants, IL-8 and Formyl-Methionyl-Leucyl-Phenylalanine, Regulate Granulocyte Colony-Stimulating Factor Signaling by Inducing Suppressor of Cytokine Signaling-1 Expression1 (2004) (44)
- Regulation of beta2-microglobulin expression in different human cell lines by proinflammatory cytokines. (1999) (44)
- Messenger RNA activities of four acute phase proteins during inflammation (1983) (44)
- Induction of CCL13 expression in synovial fibroblasts highlights a significant role of oncostatin M in rheumatoid arthritis. (2009) (44)
- Circular dichroism of ribonucleoprotein complexes from rat liver nuclei. (1977) (43)
- Mechanisms of SOCS3 Phosphorylation upon Interleukin-6 Stimulation (2005) (43)
- A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor. (2002) (42)
- Studies on the Interleukin-6-type Cytokine Signal Transducer gp130 Reveal a Novel Mechanism of Receptor Activation by Monoclonal Antibodies* (2000) (42)
- Cultured Ito cells of rat liver express the α2‐macroglobulin gene (1987) (42)
- Synthesis of a larger precursor for the subunit IV of rat liver cytochrome c oxidase in a cell-free wheat germ system. (1980) (42)
- Interleukin-6 plays a crucial role in the hepatic expression of SOCS3 during acute inflammatory processes in vivo. (2005) (41)
- Activation of NF-κB by IL-1β blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human γ-fibrinogen gene (2007) (41)
- Expression of interleukin 6 in the rat striatum following stereotaxic injection of quinolinic acid (1998) (41)
- The inflammation mediators interleukin 1 and hepatocyte‐stimulating factor are differently regulated in human monocytes (1987) (40)
- A Single STAT Recruitment Module in a Chimeric Cytokine Receptor Complex Is Sufficient for STAT Activation* (1997) (40)
- Polarity and lipid raft association of the components of the ciliary neurotrophic factor receptor complex in Madin-Darby canine kidney cells (2004) (40)
- IL-31 receptor alpha expression in epidermal keratinocytes is modulated by cell differentiation and interferon gamma. (2009) (39)
- A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction. (2000) (38)
- Different effects of the glucosidase inhibitors 1-deoxynojirimycin, N-methyl-1-deoxynojirimycin and castanospermine on the glycosylation of rat alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein. (1986) (38)
- Cell-free synthesis of rat alpha 2-macroglobulin and induction of its mRNA during experimental inflammation. (1983) (38)
- The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone. (1993) (38)
- Oncostatin M Receptor-mediated Signal Transduction Is Negatively Regulated by SOCS3 through a Receptor Tyrosine-independent Mechanism* (2006) (38)
- Isolation and characterization of a membrane-bound proteinase from rat liver. (1976) (37)
- Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited. (2001) (37)
- Discrimination of hepatocyte‐stimulating activity from human recombinant tumor necrosis factor α (1987) (37)
- Biosynthesis and Secretion of α1-Antitrypsin in Primary Cultures of Rat Hepatocytes (1982) (37)
- Two Different Epitopes of the Signal Transducer gp130 Sequentially Cooperate on IL-6-Induced Receptor Activation1 (2000) (37)
- Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene. (2007) (35)
- Intrahepatic synthesis of tumor necrosis factor-&agr; related to cardiac surgery is inhibited by interleukin-10 via the Janus kinase (Jak)/signal transducers and activator of transcription (STAT) pathway* (2003) (35)
- The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized madin-darby canine kidney cells. (2000) (35)
- The cytokine receptor gp130 and its soluble form are under hormonal control in human endometrium and decidua. (2004) (35)
- Proteolytic enzymes of rat liver mitochondria. Evidence for a mast cell origin (1979) (35)
- Induction of alpha 1-acid glycoprotein by recombinant human interleukin-1 in rat hepatoma cells. (1988) (35)
- A completely foreign receptor can mediate an interferon‐γ‐like response (2001) (34)
- Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases. (2006) (33)
- Gene therapy of human melanoma. Immunization of patients with autologous tumor cells admixed with allogeneic melanoma cells secreting interleukin 6 and soluble interleukin 6 receptor. (1995) (33)
- Box 2 Region of the Oncostatin M Receptor Determines Specificity for Recruitment of Janus Kinases and STAT5 Activation* (2008) (32)
- Soluble human interleukin‐6‐receptor modulates interleukin‐6‐dependent N‐glycosylation of α1‐protease inhibitor secreted by HepG2 cells (1992) (32)
- Different epitopes are required for gp130 activation by interleukin‐6, oncostatin M and leukemia inhibitory factor (2000) (32)
- Intracellular retention of interleukin-6 abrogates signaling. (1993) (32)
- Dual Function of Interleukin-1β for the Regulation of Interleukin-6-induced Suppressor of Cytokine Signaling 3 Expression* (2004) (31)
- ME3738 protects from concanavalin A‐induced liver failure via an IL‐6‐dependent mechanism (2003) (31)
- Alpha 2‐macroglobulin gene expression during rat development studied by in situ hybridization. (1986) (30)
- Use of immobilized synthetic peptides for the identification of contact sites between human interleukin‐6 and its receptor (1996) (30)
- Membrane‐bound and Soluble Interleukin‐6 Receptor: Studies on Structure, Regulation of Expression, and Signal Transduction a (1995) (29)
- Human ciliary neurotrophic factor: a structure-function analysis. (1995) (29)
- Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor. (1999) (29)
- Comparison of the effects of insulin, PDGF, interleukin-6, and interferon-g on glucose transport in 3T3-L1 cells: lack of cross-talk between tyrosine kinase receptors and JAK/STAT pathways (1996) (29)
- Synthesis of alpha 1-antitrypsin in rat-liver hepatocytes and in a cell-free system. (1982) (29)
- Termination of IL‐6‐induced STAT activation is independent of receptor internalization but requires de novo protein synthesis (2000) (29)
- Involvement of various organs in the initial plasma clearance of differently glycosylated rat liver secretory proteins. (1988) (28)
- Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP (2007) (28)
- Prostaglandin E1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK1/2, but not STAT3, activation. (2008) (28)
- Tissue inhibitor of metalloproteinases‐2 (TIMP‐2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2 (1995) (28)
- A complex of the soluble interleukin‐6 receptor and interleukin‐6 is internalized via the signal transducer gp130 (1996) (28)
- Inhibition by recombinant human interleukin‐6 of the glucagon‐dependent induction of phosphoenolpyruvate carboxykinase and of the insulin‐dependent induction of glucokinase gene expression in cultured rat hepatocytes: Regulation of gene transcription and messenger RNA degradation (1994) (28)
- Definition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesis. (1999) (27)
- Participation of two Ser-Ser-Phe-Tyr repeats in interleukin-6 (IL-6)-binding sites of the human IL-6 receptor. (1996) (27)
- SHPS-1/SIRP1alpha contributes to interleukin-6 signalling. (2008) (27)
- [Transketolase from human erythrocytes. Purification and properties]. (1971) (27)
- Selective coupling of STAT factors to the mouse prolactin receptor. (1998) (26)
- Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins. (1988) (26)
- Secretion of high‐mannose‐type α1‐proteinase inhibitor and α1‐acid glycoprotein by primary cultures of rat hepatocytes in the presence of the mannosidase I inhibitor 1‐deoxymannojirimycin (1985) (26)
- Hydrophobic interactions of cytochrome c oxidase. Application to the purification of the enzyme from rat liver mitochondria. (1979) (26)
- The development of rat α2‐macroglobulin (1988) (26)
- The signal transducer gp130: Solution structure of the carboxy‐terminal domain of the cytokine receptor homology region (2008) (26)
- Hemodynamic variables and plasma levels of PGI2, TXA2 and IL-6 in a porcine model of recurrent endotoxemia. (1991) (26)
- Subcellular distribution of histone-degrading enzyme activities from rat liver. (1976) (24)
- Cell-free-synthesized interleukin-6 (BSF-2/IFN-beta 2) exhibits hepatocyte-stimulating activity. (1988) (24)
- Human CNTF and related cytokines: effects on DRG neurone survival (1995) (24)
- Reconstitution of two isoforms of the human interleukin‐11 receptor and comparison of their functional properties (1997) (23)
- Levels of messenger ribonucleic acids for plasma proteins in rat liver during acute experimental inflammation (1986) (23)
- Role of N-glycosylation for the plasma clearance of rat liver secretory glycoproteins. (1989) (23)
- Induction of alpha1-antitrypsin synthesis in human articular chondrocytes by interleukin-6-type cytokines: evidence for a local acute-phase response in the joint. (1999) (23)
- The inhibitory effect of IL-1 beta on IL-6-induced alpha 2-macroglobulin expression is due to activation of NF-kappa B. (2001) (23)
- Microheterogeneity of human interleukin 6 synthesized by transfected NIH/3T3 cells: Comparison with human monocytes, fibroblasts and endothelial cells (1990) (22)
- Novel Inhibitors for Murine and Human Leukemia Inhibitory Factor Based on Fused Soluble Receptors* (2008) (22)
- Interleukin-6-resistant melanoma cells exhibit reduced activation of STAT3 and lack of inhibition of cyclin E-associated kinase activity. (2001) (22)
- Proteolytic processing of polypeptides during the biosynthesis of subcellular structures. (1982) (22)
- Signal transducer and activator of transcription STAT3 plays a major role in gp130-mediated acute phase protein gene activation. (2003) (22)
- The effect of urea on the structure of nuclear ribonucleoprotein particles from rat liver. (1979) (22)
- Molecular Mechanism of Action of the Antibiotic Rifampicin (1985) (21)
- Transforming growth factor beta 1 regulates tissue inhibitor of metalloproteinases-1 expression in differentiated human articular chondrocytes. (1994) (21)
- Low molecular weight RNAs as components of nuclear ribonucleoprotein particles containing heterogeneous nuclear RNA. (1979) (21)
- Identification of the domain in the human interleukin-11 receptor that mediates ligand binding. (2001) (21)
- The localization of an intracellular membrane-bound proteinase from rat liver. (1978) (21)
- Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130. (2006) (20)
- Identification and sequencing of cDNA clones for the rodent negative acute-phase protein alpha 1-inhibitor 3. (1987) (20)
- Regulation of interleukin‐6 receptor expression by interleukin‐6 in human monocytes — a re‐examination (1994) (19)
- Structure and function of nuclear ribonucleoprotein complexes. (1978) (19)
- The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric receptor complex mediates negative regulation of LIF signalling. (2005) (19)
- Development of an IL-6 inhibitor based on the functional analysis of murine IL-6Ralpha(1). (2009) (19)
- Increased PRPP synthetase activity in rapidly growing hepatomas (1974) (18)
- [Interleukin-6: a key hormone of the acute phase reaction]. (1989) (18)
- Quiescence of CD34-negative haematopoietic stem cells is mediated by downregulation of Cyclin B and no stat activation. (2000) (17)
- An Unusual Insertion in Jak2 Is Crucial for Kinase Activity and Differentially Affects Cytokine Responses (2009) (17)
- Biosynthesis of rat alpha 1-macroglobulin. Identification of an intracellular precursor. (1987) (16)
- Three Dileucine-like Motifs within the Interbox1/2 Region of the Human Oncostatin M Receptor Prevent Efficient Surface Expression in the Absence of an Associated Janus Kinase* (2006) (16)
- Molecular cloning and expression of an intracellular serpin: an elastase inhibitor from horse leucocytes. (1993) (16)
- Unglycosylated rat alpha 1-proteinase inhibitor has a six-fold shorter plasma half-life than the mature glycoprotein. (1985) (16)
- Biosynthesis and regulation of rat alpha 1-inhibitor3, a negative acute-phase reactant of the macroglobulin family. (1987) (16)
- Time course of IL-6 and TNF alpha release during endotoxin-induced endotoxin tolerance in rats. (1991) (15)
- Different oligosaccharide processing of the membrane‐integrated and the secretory form of gp 80 in rat liver. (1986) (15)
- The size and distribution of cytochrome c oxidase subunit IV mRNA between free and membrane-bound polyribosomes. (1981) (15)
- Phage-displayed recombinant single-chain antibody fragments with high affinity for cholesteryl ester transfer protein (CETP): cDNA cloning, characterization and CETP quantification (2004) (15)
- Human α2‐Macroglobulin as a Cytokine‐Binding Plasma Protein (1994) (15)
- Comparative studies of the effects of galactosamine and actinomycin D on nuclear ribonucleoprotein particles from rat liver. (1977) (14)
- Oncostatin M-Induced and Constitutive Activation of the JAK2/STAT5/CIS Pathway Suppresses CCL1, but Not CCL7 and CCL8, Chemokine Expression1 (2008) (14)
- Biosynthesis and secretion of α1 acute‐phase globulin in primary cultures of rat hepatcytes (1985) (14)
- Regulation of α2‐Macroglobulin Gene Expression by Interleukin‐6 a (1994) (14)
- Expression of a biologically active murine tissue inhibitor of metalloproteinases-1 (TIMP-1) in baculovirus-infected insect cells. Purification and tissue distribution in the rat. (1995) (14)
- N‐terminal amino acid sequences of precursor and mature forms of α‐1‐antitrypsin (1983) (14)
- A novel SH-type carboxypeptidase in the inner membrane of rat-liver mitochondria. (1979) (14)
- Site‐directed mutagenesis of human CNTF: Functional analysis of recombinant variants (1995) (13)
- The development of rat alpha 2-macroglobulin. Studies in vivo and in cultured fetal rat hepatocytes. (1988) (13)
- Deglycosylation of alpha 1-proteinase inhibitor by endo-beta-N-acetylglucosaminidase F. (1985) (13)
- Inhibition of cytosolic phospholipase A(2) attenuates activation of mitogen-activated protein kinases in human monocytic cells. (2000) (12)
- Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties. (1997) (12)
- The Vesicular Stomatitis Virus Matrix Protein Inhibits Glycoprotein 130-Dependent STAT Activation1 (2001) (12)
- JAK/STAT signaling in cancer (2006) (12)
- Hexa- and pentapeptide extension of proalbumin: feedback inhibition of albumin synthesis by its propeptide in isolated hepatocytes and in the cell-free system. (1982) (12)
- Inhibition of cell-free protein synthesis by low-molecular-weight RNAs from free cytoplasmic ribonucleoprotein particles. (1982) (12)
- Differential inhibition of IL‐6‐type cytokine‐induced STAT activation by PMA (2000) (12)
- The effect of sodium chloride on the structure of ribonucleoprotein particles from rat liver nuclei. (1979) (12)
- Monoclonal antibodies against the human interleukin-11 receptor alpha-chain (IL-11Rα) and their use in studies of human mononuclear cells (2000) (12)
- Benzo‐1,3‐dioxolium Salts (1965) (11)
- A completely foreign receptor can mediate an interferon-gamma-like response. (2001) (11)
- This information is current as Cytokine Signaling 3 Differentially Modulated by Suppressor of Primary Human Macrophages Is Activation of STAT 3 by IL-6 and IL-10 in (2003) (10)
- 40 INTERLEUKIN-6 SIGNALING DURING THE ACUTE-PHASE RESPONSE OF THE LIVER (2009) (10)
- Functional expression of the interleukin-11 receptor alpha-chain in normal colonic epithelium and colon cancer (2006) (10)
- Cell-free synthesis of a larger-molecular-weight precursor of cytochrome c oxidase subunit V from rat liver and the distribution of its mRNA between free and membrane-bound polysomes. (1982) (10)
- Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential. (2001) (10)
- Cleavage specificity of the serine proteinase from rat liver mitochondria. (1978) (9)
- Interleukin-6, Its Hepatic Receptor and the Acute Phase Response of the Liver (1991) (9)
- Termination and modulation of IL-6-type cytokine signaling. (2001) (9)
- Mesangial cell gelatinase A synthesis is attenuated by oscillating hyperbaric pressure. (2002) (9)
- Bow to your partner for signaling (2005) (8)
- ATP-activated, high-molecular-mass proteinase-I from rat skeletal muscle is a cysteine proteinase-alpha 1-macroglobulin complex. (1989) (8)
- Synthesis of α2‐macroglobulin in rat hepatocyte and in a cell‐free system (1983) (8)
- Effect of the alpha-glucosidase inhibitor N-hydroxyethyl-1-deoxynojirimycin (Bay m 1099) on the biosynthesis of liver secretory glycoproteins. (1989) (8)
- Cytokines in liver injury and repair (2002) (7)
- The role of N-glycosylation for the plasma clearance of rat liver secretory glycoproteins. (1989) (7)
- The signal transducer gp130--bacterial expression, refolding and properties of the carboxy-terminal domain of the cytokine-binding module. (1997) (7)
- Interaction of mature, unglycosylated and cell-free synthesized rat alpha 1-proteinase inhibitor with elastase. (1983) (7)
- Clearance of acute-phase plasma proteins with no, high-mannose-, hybrid-, or complex type oligosaccharide side chains by the isolated perfused rat liver. (1986) (7)
- Studies on the preparation and properties of ribonucleoprotein particles from rat liver nuclei. (1978) (7)
- The localization of a proteinase within rat liver mitochondria. (1977) (7)
- Aryl‐Substituted Dialkoxycarbonium Ions as Alkylating Agents (1966) (7)
- Biosynthesis and secretion of alpha 1-antitrypsin in primary cultures of rat hepatocytes. Characterization of differently glycosylated intracellular and extracellular forms. (1982) (7)
- Prostaglandin E 1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK 1 / 2 , but not STAT 3 , activation (2008) (7)
- Cultured Ito cells of rat liver express the alpha 2-macroglobulin gene. (1987) (6)
- The effect of D-galactosamine and actinomycin D on polysomes and messenger RNA levels in rat liver. (1981) (6)
- A Region within the Cytoplasmic Domain of the Interleukin‐6 Signal Transducer gp130 Important for Ligand‐induced Endocytosis of the IL‐6 Receptor (1995) (6)
- Rat lung tissue is a site of alpha 1-proteinase inhibitor synthesis: evidence by cell-free translation. (1984) (6)
- Signaling through a Mutant IFN-γ Receptor (2005) (6)
- Changes in chromatin during the development of liver cell injury induced by galactosamine (1976) (6)
- Catalytic activity and arrangement of subunit polypeptides in rat liver cytochrome c oxidase as studied by proteolysis. (1980) (5)
- Signaling through a mutant IFN-gamma receptor. (2005) (5)
- Murine interleukin 1 stimulates alpha 2-macroglobulin synthesis in rat hepatocyte primary cultures. (1985) (5)
- Signalling of interleukin-6 type cytokines via gp130, leukemia inhibitory factor (LIF) receptor and oncostatin M receptor. (2000) (5)
- Hepatocyte specific long lasting inhibition of protein N-glycosylation by D-galactosamine. (1990) (5)
- Regulation of alpha 2-macroglobulin gene expression by interleukin-6. (1994) (5)
- Regulation of alpha 2-macroglobulin gene expression by interleukin-6 (BSF-2/HSF). (1988) (4)
- Interleukin-6 in autoimmune diseases (2004) (4)
- Interleukin-6 andtheacutephase response (1990) (4)
- In vitro‐generated stem cell leukaemia showing altered cell cycle progression with distinct signalling of the tyrosine‐phosphorylated rasGAP‐associated p62dok protein (2000) (4)
- Human alpha 2-macroglobulin as a cytokine-binding plasma protein. A study with rh-interleukin-1 beta and rh-interleukin-6. (1994) (4)
- Inactivation of Glutamine Synthetase in Intact E. coli Cells (1972) (4)
- Mitogen-activated protein kinases control p 27 / Kip 1 expression and growth of human melanoma cells (4)
- Mechanisms of intracellular protein catabolism. Intracellular fate of microinjected polypeptides translated in vitro. (1987) (4)
- Proteinases as probes of the structure of rat liver ribonucleoprotein particles carrying heterogeneous nuclear RNA. (1979) (3)
- The structure of ribonucleoprotein particles from rat liver nuclei (1981) (3)
- Studies on the structure and function of IL-6 and its receptor (1992) (3)
- The interleukin-11/receptor complex: rational design of agonists/antagonists and immunoassays potentially useful in human therapy. (1998) (3)
- Circulatory life time and organ distribution of differently glycosylated forms (unglycosylated, high-mannose type, hybrid type, complex type) of rat alpha-1-acid glycoprotein. (1989) (3)
- Interferon-gamma regulates alpha 2-macroglobulin and alpha 1-antichymotrypsin expression on the pretranslational level in HepG2 cells. (1992) (3)
- Rat liver cytochrome c oxidase subunits IV and V: cell-free synthesis as larger molecular weight precursors, mRNA sizes and sites of synthesis. (1982) (3)
- Localization and Some Properties of a Proteinase and a Carboxypeptidase from Rat Liver (1979) (2)
- Synthesis of rat-liver lactate dehydrogenase and characterization of its mRNA. (1983) (2)
- Real time analysis of oncogenic STAT3 in single cells (2006) (2)
- Monoclonal antibodies against the human interleukin-11 receptor alpha-chain (IL-11Ralpha) and their use in studies of human mononuclear cells. (2000) (2)
- A lipid-soluble antioxidant from polyallomer centrifuge tubes. (1974) (2)
- Limited proteolysis of the very‐lysine‐rich histone H1 by a membrane‐bound proteinase from rat liver (1976) (2)
- Complexes with Glycoprotein 130 Signal Transduction in Heterodimeric Receptor and Oncostatin M Receptor to Contributions of Leukemia Inhibitory Factor (1999) (2)
- REVIEW ARTICLE Principles of interleukin (IL)-6-type cytokine signalling and its regulation 1 (2003) (2)
- The effect of inhibitors of transcription and translation on chromosomal proteins. (1978) (2)
- Proteolytic precursor processing in the biosynthesis of mitochondria. (1981) (1)
- Small cytoplasmic RNAs from rat liver mRNP particles (1983) (1)
- Cytokine-mediated growth inhibition of human melanoma cells. (2001) (1)
- Coenzyme Apoenzyme Interactions: Studies on the Binding of Thiamine Diphosphate to Apotransketolase From Baker’s Yeast (1976) (1)
- Biosynthesis of rat alpha 2-macroglobulin. (1985) (1)
- Synthesis of alpha 2-macroglobulin in rat hepatocytes and in a cell-free system. (1983) (1)
- Erratum to: A fusion protein of interleukin‐11 and soluble interleukin‐11 receptor acts as a superagonist on cells expressing gp130 (FEBS 21942) (1999) (1)
- TUMOR-NECROSIS-FACTOR (TNF), INTERFERON-ALPHA, INTERFERON-GAMMA AND INTERFERON-BETA-1 DO NOT EXHIBIT HEPATOCYTE STIMULATING (HSF) ACTIVITY (1987) (1)
- Modulation and termination of interleukin-6 signalling. (2000) (1)
- Human melanoma gene therapy: from animal studies to clinical trials (1996) (1)
- [Regulatory mechanisms of enzymes in carbohydrate metabolism]. (1975) (1)
- STAT Activation Protein Inhibits Glycoprotein 130-Dependent The Vesicular Stomatitis Virus Matrix (2001) (1)
- 360 Cross-regulation of cytokine signalling: Pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation (2008) (1)
- Negative Regulation der Oncostatin M-vermittelten Signaltransduktion (2006) (1)
- Polysomal and cytoplasmic mRNP particles containing 7S(L) RNA. (1984) (1)
- Different susceptibilities of complex-, hybrid- and high-mannose-type α1- inhibitor and α1-acid glycoprotein to endo-β-N-acetylglucosaminidase F and peptide:N-glycosidase F (1986) (1)
- The Interaction of Native and Chemically Modified Yeast Transketolase with a Specific Antibody (1974) (1)
- Acute phase protein synthesis: Regulation by the action of the cytokines interleukin-6, interleukin-1 and tumor necrosis factor α (1989) (1)
- Induction of the proteinase inhibitor alpha 2-macroglobulin in rat hepatocytes by a monocyte-derived factor. (1988) (1)
- IL-11 receptor (IL-11Ra) is mainly expressed on epithelial cells in normal colonic mucosa (2000) (1)
- Cell Density-Dependent Increase of Constitutive Signal Transducers and Activators of Transcription 3 Activity in Melanoma Cells Is Mediated (2007) (1)
- MECHANISMS OF SOCS3 PHOSPHORYLATION UPON IL-6 STIMULATION: CONTRIBUTIONS OF SRC- AND RECEPTOR TYROSINE KINASES (2005) (0)
- EVIDENCE FOR LOW MOLECULAR WEIGHT RNA AS CONTROL ELEMENT OF THE TRANSLATIONAL EFFICIENCY OF RNA FROM RAT LIVER NON-POLYSOMAL mRNP PARTICLES (1981) (0)
- Regulation of Rat α2-Macroglobulin Gene Activity (1985) (0)
- THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE (1999) (0)
- 1 MECHANISMS OF SOCS 3 PHOSPHORYLATION UPON IL-6 STIMULATION : CONTRIBUTIONS OF SRC-AND RECEPTOR TYROSINE KINASES (2005) (0)
- [Hepatology. New research results in its significance for the understanding of liver diseases]. (1991) (0)
- Modulation of STAT3 Gene Transcription through the PI 3-Kinase/Akt Pathway: Interaction between the Transcription Factors FKHR and STAT3 (2001) (0)
- Gene expression of the high molecular weight proteinase inhibitor alpha 2-macroglobulin. (1992) (0)
- Gene Therapy of Human Melanoma — from Animal Experiments to the Clinical Trial (1997) (0)
- Subnucleäre Lokalisation des Transkriptionsfaktors STAT3 (2004) (0)
- Immunological methods for the detection of proteins synthesized in cell free systems in rat hepatocytes and escherichia coli cells transformed with recombinant dna (1982) (0)
- Contents (2014) (0)
- Signal Transducer Glycoprotein 130 Extracellular Domains for Activation of the Importance of the Membrane-Proximal Tacken (1999) (0)
- Immune response against genetically modified tumour cells (1996) (0)
- Isolation of genomic DNA clones coding for the α2-macroglobulin of rat (1984) (0)
- Participation of two Ser-Ser-Phe-Tyr repaets in IL-6 and binding sites gp130 of human Interleukin-6 receptor (1995) (0)
- Biomarkers of Disease: IL-6-type cytokines and signalling in inflammation (2002) (0)
- Precursor Processing in the Biosynthesis of Rat liver Cytochrome c Oxidase (1981) (0)
- Regulation of suppressor of cytokine signalling 3 expression by the pro-inflammatory cytokine (IL-1beta) in vitro and inflammatory stimuli in vivo (2005) (0)
- [280] IL-1 NF-KAPPA B DEPENDENTLY INHIBITS IL-6-INDUCED EXPRESSION OF HUMAN GAMMA-FIBRINOGEN BY BLOCKING LATE PHASE STATS-ACTIVATION (2007) (0)
- Signal Attenuation M: Structural Receptor Requirements for Leukemia-Inhibitory Factor, and Oncostatin Signal Transduction of IL-6, (2000) (0)
- Angiotensin II increases macrophage uptake of Ox-LDL and CD36 mRNA expression: Possible role of IL-6 and inhibitory effects of fosinopril and losartan (2000) (0)
- Roles in IL-6 Signal Transduction Full-Length Glycoprotein 130 Have Different The Cytoplasmic Tyrosine Motifs in (1999) (0)
- Is Due to Activation of NF-- Macroglobulin Expression 2 α IL-6-Induced on β The Inhibitory Effect of IL-1 Graeve (2001) (0)
- Structure-function studies on human interleukin-6 (1991) (0)
- Studies on the structure and function of IL-6 and its hepatic receptor (1992) (0)
- 126 The STAT signalling in hepatocytes is responsible for IL6/P130 dependent protection during concanavalin A-induced liver failure (2003) (0)
- Interleukin-6 Receptor (2020) (0)
- Regulation of IL-6 signal transduction, contributions of the Signal Regulatory Protein (SIRP) and cyclic AMP (2007) (0)
- Cytokine Responses Kinase Activity and Differentially Affects An Unusual Insertion in Jak 2 Is Crucial for (2009) (0)
- Cytokine-resistant melanoma cells exhibit reduced DNA binding of STAT3 and lack of inhibition of cyclin E-associated kinase activity (1998) (0)
- N-terminal amino acid sequences of precursor and mature forms of alpha-1-antitrypsin. (1983) (0)
- Strobl, Velmurugesan Arulampalam, A completely foreign receptor can mediate an interferon- g -like response (0)
- Table of Contents (1986) (0)
- IL-6 Antagonistic Activity of Soluble gp130 on Soluble IL-6 Receptor Potentiates the (1998) (0)
- Structural Bases of Receptor-JAK-STAT Interactions (2003) (0)
- Secretion of high-mannose-type alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein by primary cultures of rat hepatocytes in the presence of the mannosidase I inhibitor 1-deoxymannojirimycin. (1985) (0)
- Immunological Methods for the Detection of Proteins. Application to Proteins Synthesized in Cell Free Systems in Rat Hepatocytes and by E. Coli Cells Transformed with Recombinant DNA (1983) (0)
- INDUCTION IN RAT HEPATOCYTES HEPATOMA-CELLS OF THE ACUTE PHASE RESPONSE - EFFECTS OF DIFFERENT MEDIATORS (1987) (0)
- Regulation of proteinase activity by high molecular weight inhibitors: biosynthesis of rat alpha-macroglobulins. (1988) (0)
- Constitutive SOCS3 expression confers a growth advance to a human melanoma cell line (2006) (0)
- Regulation of the α2-Macroglobulin Gene (2020) (0)
- Biosynthesis and secretion of alpha 1 acute-phase globulin in primary cultures of rat hepatocytes. (1985) (0)
- Molecular and biochemical characterization of suppressor of cytokine signaling-3 (SOCS-3) and SH2-containing phosphatase 1 (SHP-1) in the context of G-CSF) and erythropoietin signaling (2002) (0)
- Legrès LG (Ann N Y Acad Sci. 1994) (2015) (0)
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