Philip D. Whanger
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Philip D. Whangerbiology Degrees
Biology
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Biochemistry
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Chemistry Biology
Philip D. Whanger's Degrees
- PhD Biochemistry Stanford University
- Masters Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Philip D. Whanger Influential?
(Suggest an Edit or Addition)Philip D. Whanger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Selenium and its relationship to cancer: an update† (2004) (570)
- Selenocompounds in Plants and Animals and their Biological Significance (2002) (476)
- Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content. (1974) (329)
- Biological function of metallothionein. V. Its induction in rats by various stresses. (1978) (230)
- Long-term supplementation with selenate and selenomethionine: Selenium and glutathione peroxidase (EC 1.11.1.9) in blood components of New Zealand women (1993) (217)
- Cancer-protective properties of high-selenium broccoli. (2001) (198)
- Selenoprotein Gene Nomenclature* (2016) (177)
- Selenium in the treatment of heavy metal poisoning and chemical carcinogenesis. (1992) (173)
- Effect of selenium, vitamin E, and antioxidants on testicular function in rats. (1973) (163)
- Selenium and the Brain: A Review (2001) (157)
- Effects of various dietary levels of selenium as selenite or selenomethionine on tissue selenium levels and glutathione peroxidase activity in rats. (1988) (155)
- Biological function of metallothionein. I. Synthesis and degradation of rat liver metallothionein. (1975) (149)
- Deposition of dietary organic and inorganic selenium in rat erythrocyte proteins. (1986) (147)
- Determination of the distribution of selenium between glutathione peroxidase, selenoprotein P, and albumin in plasma. (1993) (143)
- Purification and properties of selenoprotein W from rat muscle. (1993) (130)
- Effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues. (1987) (118)
- Metabolism of subtoxic levels of selenium in animals and humans. (1996) (114)
- Rat skeletal muscle selenoprotein W: cDNA clone and mRNA modulation by dietary selenium. (1995) (113)
- Diversion of mercury binding in rat tissues by selenium: a possible mechanism of protection. (1974) (112)
- Selenoprotein W of rat muscle binds glutathione and an unknown small molecular weight moiety. (1996) (112)
- Chemical forms of selenium in rat tissues after administration of selenite or selenomethionine. (1986) (107)
- Selenium and Mercury Interactions with Emphasis on Fish Tissue (2009) (107)
- Selenoprotein W during development and oxidative stress. (2006) (106)
- Effect of dietary selenium on N-2 fluorenyl-acetamide (FAA)-induced cancer in vitamin E supplemented, selenium depleted rats. (1972) (103)
- Blood selenium and glutathione peroxidase activity in pregnant women: comparative assays in primates and other animals. (1982) (102)
- Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum). (2000) (92)
- Selenium - induced redistribution of cadmium binding to tissue proteins: a possible mechanism of protection against cadmium toxicity. (1975) (87)
- Uptake of selenite, selenomethionine and selenate by brush border membrane vesicles isolated from rat small intestine (1994) (80)
- Relationship of dietary selenium concentration; chemical cancer induction; and tissue concentration of selenium in rats. (1973) (79)
- Effects of dietary nickel on enzyme activities and mineral contents in rats. (1973) (78)
- Comparative metabolism of organic and inorganic selenium by sheep (1989) (78)
- Dietary selenium increases selenoprotein W levels in rat tissues. (1997) (78)
- Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium. (1991) (74)
- Blood selenium and glutathione peroxidase activity of populations in New Zealand, Oregon, and South Dakota 1 (1988) (74)
- Distribution of selenium and glutathione peroxidase in blood fractions from humans, rhesus and squirrel monkeys, rats and sheep. (1983) (73)
- Effects of selenium and vitamin E on blood selenium levels, tissue glutathione peroxidase activities and white muscle disease in sheep fed purified or hay diets. (1977) (73)
- Influence of dietary methionine on the metabolism of selenomethionine in rats. (1989) (70)
- Selenoprotein expression and function-selenoprotein W. (2009) (69)
- Selenium influences tissue levels of selenoprotein W in sheep. (1997) (69)
- Accumulation and depletion of zinc in rat liver and kidney metallothionens. (1977) (67)
- Selenium proteins in ovine tissues. II. Spectral properties of a 10,000 molecular weight selenium protein. (1973) (64)
- Selenoprotein W accumulates primarily in primate skeletal muscle, heart, brain and tongue (2004) (64)
- Urinary selenium and iodine during pregnancy and lactation. (2001) (63)
- Selenoprotein W: a review (2000) (63)
- Bioavailability to rats of selenium in various tuna and wheat products. (1983) (62)
- Intestinal absorption of selenite, selenate, and selenomethionine in the rat (1992) (60)
- Glutathione peroxidase activity and chemical forms of selenium in tissues of rats given selenite or selenomethionine. (1988) (59)
- Deliberations and evaluations of the approaches, endpoints and paradigms for selenium and iodine dietary recommendations. (1996) (58)
- Chemical forms of selenium in selenium containing proteins from human plasma. (1991) (56)
- Accumulation and depletion of zinc in chick tissue metallothioneins. (1979) (56)
- Metabolism of selenate and selenomethionine by a selenium-deficient population of men in China (1992) (55)
- Effect of feeding selenium-deficient ration to the subhuman primate (Saimiri sciureus). (1971) (54)
- Metallothionein and cu-chelatin: characterization of metal-binding proteins from tissues of four marine animals☆ (1981) (53)
- Differential influences of various arsenic compounds on glutathione redox status and antioxidative enzymes in porcine endothelial cells (2002) (53)
- Absorption of Selenite and Selenomethionine from Ligated Digestive Tract Segments in Rats 1 (1976) (53)
- Metabolism of selenium in humans (1998) (52)
- Purification, characterization, and glutathione binding to selenoprotein W from monkey muscle. (1999) (50)
- Properties of cadmium-binding proteins in rat testes. Characteristics unlike metallothionein. (1985) (47)
- Selenium proteins in ovine tissues: III. Distribution of selenium and glutathione peroxidases in tissue cytosols. (1978) (47)
- Selenium binding proteins in tissues of normal and selenium responsive myopathic lambs (1972) (47)
- Metabolism of selenite and selenomethionine in the rhesus monkey. (1990) (44)
- Rumen Microorganisms Decrease Bioavailability of Inorganic Selenium Supplements (2016) (43)
- Interactions of selenium and antioxidants with mercury, cadmium and silver. (1981) (42)
- China, a country with both selenium deficiency and toxicity: some thoughts and impressions. (1989) (42)
- Cadmium effects in rats on tissue iron, selenium, and blood pressure: blood and hair cadmium in some Oregon residents (1979) (41)
- Selenium deficiency lesions in rats fed vitamin E supplemented rations. (1971) (41)
- Effect of dietary selenium on selenoprotein W and glutathione peroxidase in 28 tissues of the rat (1998) (41)
- Evidence for selenocysteine in ovine tissue organelles. (1981) (40)
- Metabolic interactions of selenium with cadmium, mercury, and silver. (1985) (39)
- Selenium interactions with carcinogens. (1983) (39)
- Organic and inorganic selenium supplementation to lactating mothers increase the blood and milk Se concentrations and Se intake by breast-fed infants. (1998) (38)
- Glutathione peroxidase activity and selenoprotein W levels in different brain regions of selenium-depleted rats(1). (2001) (37)
- Biological function of metallothionein-IV. Biosynthesis and degradation of liver and kidney metallothionein in rats fed diets containing zinc or cadmium. (1978) (37)
- Properties of glutathione peroxidase isolated from human plasma. (1987) (36)
- Selenium, sulfur and nitrogen levels in ovine rumen microorganisms. (1978) (36)
- Effect of some copper antagonists on induction of ceruloplasmin in the rat. (1970) (36)
- Chemical forms of selenium in corn and rice grown in a high selenium area of China. (1991) (36)
- Conserved features of selenocysteine insertion sequence (SECIS) elements in selenoprotein W cDNAs from five species. (1997) (36)
- INTERACTIONS OF ZINC AND SELENIUM ON THE BINDING OF CADMIUM TO RAT TISSUE PROTEINS * (1980) (36)
- Interactive effects of organic and inorganic selenium with cadmium and mercury on spermatozoal oxygen consumption and motility in vitro. (1985) (36)
- Long-term supplementation with selenate and selenomethionine: urinary excretion by New Zealand women (1997) (35)
- Uptake of selenotrisulfides of glutathione and cysteine by brush border membranes from rat intestines. (1992) (34)
- Metabolism of selenomethionine and effects of interacting compounds by mammalian cells in culture. (1987) (33)
- Some Comparative Aspects of Selenite and Selenomethionine Metabolism (1986) (32)
- Effects of selenium deficiency on vitamin E metabolism in rats. (1977) (32)
- Selenoprotein W in overexpressed and underexpressed rat glial cells in culture. (2001) (31)
- The mechanism of action of 5'-adenylic acid-activated threonine dehydrase. II. Protomer-oligomer interconversions and related properties. (1968) (30)
- Arsenic levels in Oregon waters. (1977) (29)
- Protein technics for selenium speciation in human body fluids. (1994) (29)
- Influence of gender on selenoprotein W, glutathione peroxidase and selenium in tissues of rats. (1998) (28)
- Distribution of selenium in erythrocytes, plasma, and urine of Chinese men of different selenium status☆ (1992) (28)
- Biological function of metallothionein. VII. Effect of age on its metabolism in rats. (1979) (27)
- Cadmium and nickel influence on blood pressure, plasma renin, and tissue mineral concentrations. (1980) (26)
- Tissue metallothionein: dietary interaction of cadmium and zinc with copper, mercury, and silver. (1981) (25)
- Glutathione peroxidase activity modulates fatty acid profiles of plasma and breast milk in Chinese women. (1999) (25)
- Selenoprotein W gene regulation by selenium in L8 cells (2002) (24)
- Effects of cyanide on selenium metabolism in rats. (1984) (24)
- Effect of copper, zinc and cadmium on the promoter of selenoprotein W in glial and myoblast cells. (2002) (23)
- Effects of selenium and vitamin E deficiencies on reproduction, growth, blood components, and tissue lesions in sheep fed purified diets. (1977) (23)
- Distribution of selenium between plasma fractions in guinea pigs and humans with various intakes of dietary selenium. (1998) (22)
- Toxicity, metabolism and absorption of selenite by isolated rat hepatocytes. (1995) (22)
- Microarray analysis of selenium-depleted and selenium-supplemented mice (2006) (21)
- Metabolism of [75Se]selenite by rhesus monkeys. (1984) (21)
- Selenium supplementation of Chinese women with habitually low selenium intake increases plasma selenium, plasma glutathione peroxidase activity, and milk selenium, but not milk glutathione peroxidase activity. (2000) (21)
- Interaction of selenium and arsenic with metallothionein: effect of vitamin B12. (1994) (21)
- Metabolism of lactic, succinic and acrylic acids by rumen microorganisms from sheep fed sulfur-adequate and sulfur-deficient diets. (1967) (21)
- Ovine and bovine metallothioneins: purification, number of species, zinc content and amino acid composition. (1981) (20)
- Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline (2002) (20)
- Selenoprotein W cDNAs from five species of animals. (1997) (20)
- Metabolism of selenite in men with widely varying selenium status. (1999) (19)
- Effect of supplementary zinc on the intracellular distribution of hepatic copper in rats. (1971) (19)
- Effect of dietary sulfur upon the fatty acid production in the rumen. (1965) (19)
- Ovine and bovine metallothioneins: accumulation and depletion of zinc in various tissues. (1981) (18)
- Influence of sulfur on incidence of white muscle disease in lambs. (1969) (18)
- Effect of dietary sulfur upon the production and absorption of lactate in sheep. (1966) (17)
- Selenium and white muscle disease: effect of sulfate and energy levels on plasma enzymes and ruminal microbes. (1970) (17)
- Influence of diet on the effects of selenium in the genesis of mammary tumors. (1982) (17)
- Effects of various methods of selenium administration on white muscle disease, glutathione peroxidase and plasma enzyme activities in sheep. (1978) (17)
- Effect of selenium on methylmercury binding to subcellular and soluble proteins in rat tissues. (1975) (16)
- Quantitative significance of measuring trimethylselenonium in urine for assessing chronically high intakes of selenium in human subjects (1999) (15)
- Sulfur in ruminant nutrition. (1972) (15)
- Effect of vitamin B12 status on selenium methylation and toxicity in rats: in vivo and in vitro studies. (1993) (15)
- Incorporation of selenium-75 into semen and reproductive tissues of bulls and rams. (1983) (15)
- Effect of dietary selenium restriction on selected parameters of selenium status in men with high life-long intake. (1999) (15)
- Effects of dietary mercury level and cadmium on rat tissue metallothionein: mercury binding and influences on zinc. (1983) (14)
- Selenoprotein W, Selenium and Glutathione Peroxidase in Rat and Sheep Brains and in Brain Cell Cultures. (1999) (14)
- Metabolism of subtoxic level of selenite by double-perfused small intestine in rats (2004) (14)
- Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells (2006) (14)
- Effects of selenium and serum on selenoprotein W in cultured L8 muscle cells (2004) (14)
- Fatty acid and glucose metabolism in selenium deficient rats and lambs. (1977) (13)
- Selenium supplementation increases the polyunsaturated fatty acid content of human breast milk (1999) (13)
- Selective production of rat mutant selenoprotein W with and without bound glutathione. (2004) (13)
- Selenium metabolism and glutathione peroxidase activity in cultured human lymphoblasts (1992) (12)
- Effects of selenium, cadmium, mercury, tellurium, arsenic, silver and cobalt on white muscle disease in lambs and effect of dietary forms of arsenic on its accumulation in tissues (1976) (12)
- Effects of feeding selenium deficient diets to rhesus monkeys (Macaca Mulatta). (1988) (12)
- Enzyme activities of ruminant digestive tract epithelial tissue. (1970) (12)
- Tissue lactic dehydrogenase, glutamic-oxalacetic transaminase, and peroxidase changes of selenium-deficient myopathic lambs. (1969) (11)
- Effects of vitamin B-6 deficiency on selenium metabolism in the rat. (1989) (11)
- Effect of vitamin B12 on performance and tissue selenium content in rats fed sub-toxic levels of selenite. (1993) (11)
- Nutritional and environmental factors affecting metallothionein levels. (1979) (11)
- Calcium uptake and ATPase activity of sarcoplasmic reticulum vesicles isolated from control and selenium deficient lambs. (1993) (11)
- Tissue lysosomal enzyme changes in selenium-deficient myopathic lambs. (1970) (11)
- Selenoprotein W. (2002) (10)
- Distribution of selenium between fractions in erythrocytes, plasma, hair, and fingernails of Chinese women living in selenium‐deficient, ‐adequate, and ‐excessive areas of China (2000) (10)
- Selenium (Se) and Glutathione Peroxidase (GSH-Px) in Blood Components of NZ Women During Long Term Supplementation with Selenate or Selenomethionine (Semet) (1989) (10)
- Selenoprotein W: A muscle protein in search of a function (2001) (10)
- Identification of putative transcription factor binding sites in rodent selenoprotein W promoter. (2004) (9)
- Influence of copper status on copper-64 metabolism in the rat. (1969) (9)
- Metabolism of selenium by pregnant women (1992) (9)
- Dietary pyrrolizidine (Senecio) alkaloids and tissue distribution of copper and vitamin A in broiler chickens. (1992) (8)
- Chemical forms of selenium present in rat and ram spermatozoa (2000) (8)
- Tissue sulfhydryl groups in selenium-deficient rats and lambs. (1973) (8)
- 5 – Factors Affecting the Metabolism of Nonessential Metals in Food (1982) (8)
- Urinary Excretion of Selenium (Se) and Trimethyl-selenonium (TMSe) by NZ Women During Long Term Supplementation with Selenate or Selenomethionine (Semet) (1989) (8)
- Influence of silver, mercury, lead, cadmium, and selenium on glutathione peroxidase and transferase activities in rats (1979) (7)
- METABOLISM OF ORALLY ADMINISTERED 75SE-SELENITE BY THE PIG. (1985) (7)
- Occurrence of myopathy in lambs of ewes fed added arsenic in a selenium-deficient ration. (1971) (7)
- Some immunochemical properties of rat liver and kidney metallothioneins. (1980) (6)
- Glutathione peroxidase activity and selenoprotein W levels in different brain regions of selenium-depleted rats11Published with the approval of Oregon State University Experiment Station as technical paper no. 11,624. (2001) (6)
- Deletion analysis of the rodent selenoprotein W promoter. (2005) (6)
- The effects of selenium deficiency on differentiation, degradation, dand cell lysis of L8 rat skeletal muscle cells (1999) (5)
- Metabolism of different forms of selenium in humans : Conference on trace elements in health and disease (1993) (5)
- Effect of dietary fluoride on selenite toxicity in the rat (1992) (5)
- Effect of cadmium administration on absorption, retention, and excretion of zinc-65 administered to rats. (1981) (5)
- Role of metallothionein in zinc metabolism. (1982) (5)
- Bioavailability to rats of selenium in ovine muscle, liver and hemoglobin (1991) (4)
- Low molecular weight cadmium and selenium containing proteins unlike metallothionein in animals. (1987) (4)
- Free plasma amino acids in selenium-deficient lambs and rats. (1972) (4)
- Effect of dietary cadmium on intracellular distribution of hepatic iron in rats. (1973) (4)
- Isolation of metallothionein from ovine and bovine tissues. (1991) (3)
- Influence of arsenic on selenium metabolism and glutathione peroxidase activity in rats. (1991) (3)
- Influence of dietary selenium on metabolism of cadmium and mercury in reproductive tissues of rats (1987) (3)
- Determination of the distribution of selenium between selenoprotein P, glutathione peroxidase and albumin in plasma (1991) (3)
- Selenium Studies — Trepidations, Tissue Calcification and Selenoamino Acids (1981) (3)
- Baseline selenium and prostate cancer risk: comments and open questions. (2014) (3)
- In vitro metabolism of 75Se-selenite and 75Se-selenomethionine in chick blood. (1989) (3)
- Variations in the distribution of selenium between erythrocyte glutathione peroxidase and hemoglobin in different human populations (1986) (2)
- Comparative Effects of Selenium Deficiency on Male Reproduction in Several Mammalian Species (1981) (2)
- Effects of selenium and vitamin E deficiencies in lambs on hepatic microsomal hemoproteins and mitochondrial respiration. (1977) (2)
- Inducibility and amounts of metallothionein as influenced by cadmium and zinc in the developing rat (1983) (2)
- Comparative effects of diethylstilbestrol and diallylhexestrol on digestion and nitrogen metabolism in sheep. (1964) (2)
- Biological function of metallothionein. VI. Metabolic interaction of cadmium and zinc in rats (1980) (2)
- Collagenase Activity in Tissues of Selenium Responsive Myopathic Lambs 1 (1973) (1)
- Uptake of75Se in cataractous rat lens proteins (1984) (1)
- Enzyme changes in rats with terminal liver necrosis due to vitamin E and selenium deficiencies (1971) (1)
- Cloning and Tissue Distribution of Chicken Selenoprotein W (2007) (1)
- Effects of Transsulfuration Defects on Selenium Status (1988) (1)
- Selenium-Containing Proteins in Plasma of Higher Primates (1989) (1)
- The Relationship of Dietary Selenium to Carcinogenesis (1996) (1)
- Mineral and vitamin interactions of steers in a Mediterranean climate (1994) (1)
- Investigation of the form of selenium in the hydrogenase from chemolithotrophically cultured Bradyrhizobium japonicum (1991) (1)
- Metabolism of pyruvate, succinate and glutamate by tissues from selenium-responsive myopathic lambs. (1973) (1)
- Commentary: Selenium: Selenium: Commentary (2001) (1)
- Association of selenium with tissue membranes of ovine and rat tissues (1984) (1)
- Mineral Status of Steers in Eastern Oregon (1991) (1)
- Relationship of Selenium Intake to Cancer (2005) (0)
- The effect of vitamin B sub 12 on selenium metabolism in the rat (1991) (0)
- Investigation of the form of selenium in the hydrogenase from chemolithotrophically cultured Bradyrhizobium japonicum (1990) (0)
- Rat liver metabollothionein interactions of silver, zinc, and cadmium (1982) (0)
- Purification and Properties of the Human Plasma Selenoenzyme, Glutathione Peroxidase (1988) (0)
- Platelet glutathione peroxidase during pregnancy and lactation (1994) (0)
- Effects of Dietary Sulfur on Tissue Metallothionein in Rats (1981) (0)
- Influence of zinc on copper binding in tissue proteins of steers (1991) (0)
- Metabolism of cadmium by developing rat molars (1981) (0)
- Biochemistry and Molecular Biology of Selenium. In: Environmental Bioinorganic Chemistry of Selenium. (1995) (0)
- August 28 , 1980 Title : Selenium-75 Incorporation in Semen and Reproductive Organs of the Bull and Ram (2013) (0)
- Effects of Selenium Status on Selenium Incorporation into Plasma Fractions and Excretion in Urine in Men Infused with 74Se Selenite (2002) (0)
- Rumen Microorganisms Decrease Bioavailability of Inorganic Selenium Supplements (2015) (0)
- Tissue distribution and effect of selenium deficiency on rat selenoprotein W mRNA levels (1995) (0)
- The Predicament — How should Selenoproteins be Hydrolyzed and Bioavailability Studies with Selenium Conducted? (1988) (0)
- Influence of Dietary Methionine on Selenomethionine Metabolism in Rats (1988) (0)
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