Peter H. Sugden
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Peter H. Sugden's Degrees
- Bachelors Biology University of Oxford
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(Suggest an Edit or Addition)Peter H. Sugden's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial (2021) (1083)
- Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. (1996) (561)
- "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. (1998) (512)
- Cellular mechanisms of cardiac hypertrophy (1998) (454)
- Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. (1994) (385)
- Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology (2011) (380)
- Stimulation of “Stress-regulated” Mitogen-activated Protein Kinases (Stress-activated Protein Kinases/c-Jun N-terminal Kinases and p38-Mitogen-activated Protein Kinases) in Perfused Rat Hearts by Oxidative and Other Stresses* (1998) (343)
- Stimulation of the p38 Mitogen-activated Protein Kinase Pathway in Neonatal Rat Ventricular Myocytes by the G Protein–coupled Receptor Agonists, Endothelin-1 and Phenylephrine: A Role in Cardiac Myocyte Hypertrophy? (1998) (340)
- Studies on the properties and mode of action of the purified regulatory subunit of bovine heart adenosine 3':5'-monophosphate-dependent protein kinase. (1978) (338)
- Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors. (1997) (332)
- Phenotyping hypertrophy: eschew obfuscation. (2003) (311)
- Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissue. (1977) (296)
- Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. (1994) (288)
- Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin. (1993) (267)
- Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. (1999) (259)
- The p38‐MAPK inhibitor, SB203580, inhibits cardiac stress‐activated protein kinases/c‐Jun N‐terminal kinases (SAPKs/JNKs) (1998) (253)
- Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease. (1999) (228)
- Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes. (1996) (221)
- Cellular Stresses Differentially Activate c-Jun N-terminal Protein Kinases and Extracellular Signal-regulated Protein Kinases in Cultured Ventricular Myocytes (*) (1995) (219)
- Insulin-like Growth Factor-I Rapidly Activates Multiple Signal Transduction Pathways in Cultured Rat Cardiac Myocytes* (1997) (213)
- Signaling in myocardial hypertrophy: life after calcineurin? (1999) (210)
- Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial (2021) (201)
- Regulation of protein turnover in skeletal and cardiac muscle. (1991) (201)
- Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis (2008) (198)
- Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytes. (1998) (195)
- Purification and characterization of the catalytic subunit of adenosine 3':5'-cyclic monophosphate-dependent protein kinase from bovine liver. (1976) (183)
- Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy. (1996) (177)
- ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium. (2008) (175)
- Hypertrophic Agonists Stimulate the Activities of the Protein Kinases c-Raf and A-Raf in Cultured Ventricular Myocytes (*) (1995) (173)
- Intracellular signalling through protein kinases in the heart. (1995) (172)
- An overview of endothelin signaling in the cardiac myocyte. (2003) (171)
- Small guanine nucleotide-binding proteins and myocardial hypertrophy. (2000) (170)
- Endothelin‐1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes (1993) (169)
- The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes (*) (1995) (165)
- Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses (2007) (165)
- Regulation of Mitogen-Activated Protein Kinases in Cardiac Myocytes through the Small G Protein Rac1 (2001) (161)
- Endothelin-1 is involved in norepinephrine-induced ventricular hypertrophy in vivo. Acute effects of bosentan, an orally active, mixed endothelin ETA and ETB receptor antagonist. (1996) (149)
- Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes. (2000) (147)
- Stimulation of cardiac protein synthesis by insulin-like growth factors. (1992) (144)
- PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits. (1999) (142)
- Activation of protein kinase cascades in the heart by hypertrophic G protein-coupled receptor agonists. (1999) (130)
- Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytes. (2006) (121)
- Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues. (1976) (120)
- The effects of ammonium, inorganic phosphate and potassium ions on the activity of phosphofructokinases from muscle and nervous tissues of vertebrates and invertebrates. (1975) (119)
- Effect of citrate on the activities of 6-phosphofructokinase from nervous and muscle tissues from different animals and its relationships to the regulation of glycolysis. (1977) (118)
- Ras, Akt, and Mechanotransduction in the Cardiac Myocyte (2003) (112)
- The effects of surgical stress and short-term fasting on protein synthesis in vivo in diverse tissues of the mature rat. (1988) (111)
- Regulation of Ras·GTP Loading and Ras-Raf Association in Neonatal Rat Ventricular Myocytes by G Protein-coupled Receptor Agonists and Phorbol Ester (1999) (110)
- Activities of citrate synthase, NAD+-linked and NADP+-linked isocitrate dehydrogenases, glutamate dehydrogenase, aspartate aminotransferase and alanine aminotransferase in nervous tissues from vertebrates and invertebrates. (1975) (105)
- The Expression of Constitutively Active Isotypes of Protein Kinase C to Investigate Preconditioning* (1998) (104)
- Effects of catecholamines on protein synthesis in cardiac myocytes and perfused hearts isolated from adult rats. Stimulation of translation is mediated through the alpha 1-adrenoceptor. (1990) (102)
- Untangling the Web: specific signaling from PKC isoforms to MAPK cascades. (2001) (99)
- Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes. (1995) (93)
- Regulation of mitogen-activated protein kinase cascade in adult rat heart preparations in vitro. (1994) (89)
- The effects of 6 hours of hypoxia on protein synthesis in rat tissues in vivo and in vitro. (1985) (87)
- Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: Effects of endothelin-1, oxidative stress and cytokines (2008) (82)
- The role of protein kinases in adaptational growth of the heart. (1996) (78)
- Classical, novel and atypical isoforms of PKC stimulate ANF‐ and TRE/AP‐1‐regulated‐promoter activity in ventricular cardiomyocytes (1994) (77)
- Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. (1998) (76)
- Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries. (1978) (74)
- Peptide growth factors signal differentially through protein kinase C to extracellular signal-regulated kinases in neonatal cardiomyocytes. (2006) (73)
- Expression of protein kinase C isoforms during cardiac ventricular development. (1995) (73)
- Stimulation of phosphatidylinositol hydrolysis, protein kinase C translocation, and mitogen-activated protein kinase activity by bradykinin in rat ventricular myocytes: dissociation from the hypertrophic response. (1996) (71)
- Pro-inflammatory cytokines stimulate mitogen-activated protein kinase subfamilies, increase phosphorylation of c-Jun and ATF2 and upregulate c-Jun protein in neonatal rat ventricular myocytes. (1999) (70)
- Regulation of pyruvate oxidation and the conservation of glucose. (1978) (70)
- Oncogenic src, raf, and rasStimulate a Hypertrophic Pattern of Gene Expression and Increase Cell Size in Neonatal Rat Ventricular Myocytes* (1998) (69)
- Activation of mitogen‐activated protein kinases (p38‐MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart (1998) (69)
- Regulation of phospholipases C and D in rat ventricular myocytes: stimulation by endothelin-1, bradykinin and phenylephrine. (1997) (67)
- Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants (2005) (66)
- Phosphorylation of additional sites on pyruvate dehydrogenase inhibits its re-activation by pyruvate dehydrogenase phosphate phosphatase. (1978) (63)
- Akt like a woman: gender differences in susceptibility to cardiovascular disease. (2001) (62)
- Phenylephrine and endothelin-1 upregulate connective tissue growth factor in neonatal rat cardiac myocytes. (2004) (62)
- Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition (2008) (61)
- Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein. (2002) (61)
- Signalling pathways in cardiac myocyte hypertrophy. (2001) (61)
- Cell stress-induced phosphorylation of ATF2 and c-Jun transcription factors in rat ventricular myocytes. (1997) (60)
- Amino acid sequences around the sites of phosphorylation in the pig heart pyruvate dehydrogenase complex. (1979) (58)
- Conditional Transgenic Expression of Fibroblast Growth Factor 9 in the Adult Mouse Heart Reduces Heart Failure Mortality After Myocardial Infarction (2011) (58)
- Regulation of kinase reactions in pig heart pyruvate dehydrogenase complex. (1979) (57)
- Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. (2007) (57)
- Towards a re‐definition of ‘cardiac hypertrophy’ through a rational characterization of left ventricular phenotypes: a position paper of the Working Group ‘Myocardial Function’ of the ESC (2011) (55)
- MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis (2011) (54)
- Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes (2008) (53)
- Endothelin signalling in the cardiac myocyte and its pathophysiological relevance. (2005) (53)
- Stimulation of adult rat ventricular myocyte protein synthesis and phosphoinositide hydrolysis by the endothelins. (1993) (49)
- Using U0126 to dissect the role of the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade in the regulation of gene expression by endothelin-1 in cardiac myocytes. (2006) (49)
- Phenylephrine promotes phosphorylation of Bad in cardiac myocytes through the extracellular signal-regulated kinases 1/2 and protein kinase A. (2002) (49)
- Effects of left ventricular volume overload on mitochondrial and death-receptor-mediated apoptotic pathways in the transition to heart failure. (2009) (48)
- Activation of p21‐activated protein kinase α (αPAK) by hyperosmotic shock in neonatal ventricular myocytes (1997) (48)
- Use of aromatic amino acids as monitors of protein turnover. (1981) (46)
- Rates of protein turnover in vivo and in vitro in ventricular muscle of hearts from fed and starved rats. (1984) (46)
- Activation of the small GTP-binding protein Ras in the heart by hypertrophic agonists. (2000) (44)
- Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes. (2000) (43)
- Mitogen-Activated Protein Kinases ) in the Myocardium ' ' Stress-Responsive ' ' Mitogen-Activated Protein Kinases ( c-Jun N-Terminal Kinases and (1998) (42)
- Are transgenic mice the 'alkahest' to understanding myocardial hypertrophy and failure? (2009) (41)
- Regulation of mitogen-activated protein kinase cascades in the heart. (1998) (41)
- SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions. (2013) (40)
- Inflame my heart (by p38-MAPK). (2006) (40)
- Effects of increasing extracellular pH on protein synthesis and protein degradation in the perfused working rat heart. (1989) (40)
- The effects of calcium ions, ionophore A23187 and inhibition of energy metabolism on protein degradation in the rat diaphragm and epitrochlearis muscles in vitro. (1980) (39)
- Endothelin-1-dependent signaling pathways in the myocardium. (1996) (39)
- The effects of fasting or hypoxia on rates of protein synthesis in vivo in subcellular fractions of rat heart and gastrocnemius muscle. (1989) (39)
- Cellular mechanisms of cardiac hypertrophy. (1995) (38)
- Cardiac protein kinases: the cardiomyocyte kinome and differential kinase expression in human failing hearts. (2015) (38)
- Mechanotransduction in cardiomyocyte hypertrophy. (2001) (38)
- Protein kinase activities in rat pancreatic islets of Langerhans. (1979) (38)
- Glycogen synthase kinases 3alpha and 3beta in cardiac myocytes: regulation and consequences of their inhibition. (2008) (37)
- Effects of oxidative stress on the cardiac myocyte proteome: modifications to peroxiredoxins and small heat shock proteins. (2006) (36)
- ERK1/2 Signaling Dominates Over RhoA Signaling in Regulating Early Changes in RNA Expression Induced by Endothelin-1 in Neonatal Rat Cardiomyocytes (2010) (35)
- Activities of hexokinase, phosphofructokinase, 3-oxo acid coenzyme A-transferase and acetoacetyl-coenzyme A thiolase in nervous tissue from vertebrates and invertebrates. (1973) (35)
- Conversion of inactive (phosphorylated) pyruvate dehydrogenase complex into active complex by the phosphate reaction in heart mitochondria is inhibited by alloxan-diabetes or starvation in the rat. (1978) (35)
- REGULATION OF PYRUVATE DEHYDROGENASE BY PHOSPHORYLATION/DEPHOSPHORYLATION (1979) (35)
- Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target (2012) (34)
- Redox Regulation of Cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) Controls p38-MAPK (Mitogen-Activated Protein Kinase) and Orchestrates Cardiac Remodeling to Hypertension (2020) (34)
- Protein synthesis in rat cardiac myocytes is stimulated at the level of translation by phorbol esters (1989) (33)
- A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3) (2012) (31)
- Stimulation of gene expression in neonatal rat ventricular myocytes by Ras is mediated by Ral guanine nucleotide dissociation stimulator (Ral.GDS) and phosphatidylinositol 3-kinase in addition to Raf. (1998) (31)
- Modulation of interleukin signalling and gene expression in cardiac myocytes by endothelin-1. (2010) (30)
- Characterization of stimulation of phosphoinositide hydrolysis by alpha 1-adrenergic agonists in adult rat hearts. (1994) (30)
- Signaling pathways activated by vasoactive peptides in the cardiac myocyte and their role in myocardial pathologies. (2002) (29)
- Correlations between cardiac protein synthesis rates, intracellular pH and the concentrations of creatine metabolites. (1991) (28)
- The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death (2019) (28)
- cAMP and protein synthesis in isolated adult rat heart preparations. (1993) (26)
- Regulation of Protein Kinase C δ by Phorbol Ester, Endothelin-1, and Platelet-derived Growth Factor in Cardiac Myocytes* (2006) (25)
- Contrasting response of protein degradation to starvation and insulin as measured by release of N tau-methylhistidine or phenylalanine from the perfused rat heart. (1986) (25)
- Signaling through the extracellular signal-regulated kinase 1/2 cascade in cardiac myocytes. (2004) (25)
- Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal rat cardiac myocytes: implications for the regulation of c-jun expression. (2004) (24)
- Regulation of Expression of the Rat Orthologue of Mouse Double Minute 2 (MDM2) by H2O2-induced Oxidative Stress in Neonatal Rat Cardiac Myocytes (2009) (24)
- The effects of insulin on glucose uptake and lactate release in perfused working rat heart preparations. (1982) (23)
- p90 Ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq-protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists (2012) (23)
- The apparent inhibition of phosphofrunctokinase by reduced nicotinamide-adenine dinucleotide: a problem of coupled-enzyme assays. (1970) (22)
- Regional variation and differential sensitivity of rat heart protein synthesis in vivo and in vitro. (1985) (20)
- Activities of choline acetyltransferase, acetylcholinesterase, glutamate decarboxylase, 4-aminobutyrate aminotransferase and carnitine acetyltransferase in nervous tissue from some vertebrates and invertebrates. (1977) (19)
- Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin (2010) (19)
- Protein synthesis in liver and extra-hepatic tissues after partial hepatectomy. (1990) (19)
- Acute alpha 1-adrenergic stimulation of cardiac protein synthesis may involve increased intracellular pH and protein kinase activity. (1991) (19)
- Activation of mitogen-activated protein kinases ( p 38-MAPKs , SAPKs / JNKs and ERKs ) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart (1998) (17)
- Stimulation of protein synthesis, glucose uptake and lactate output by insulin and adenosine deaminase in the rat heart (1986) (16)
- Role of multisite phosphorylation in the regulation of ox kidney pyruvate dehydrogenase complex (1980) (16)
- A comparison of rates of protein turnover in rat diaphragm in vivo and in vitro. (1986) (16)
- Stimulation of protein synthesis by raised extracellular pH in cardiac myocytes and perfused hearts (1990) (14)
- Ras: the stress and the strain. (2006) (14)
- The effects of lactate, acetate, glucose, insulin, starvation and alloxan-diabetes on protein synthesis in perfused rat hearts. (1986) (14)
- Activation of p21-activated protein kinase alpha (alpha PAK) by hyperosmotic shock in neonatal ventricular myocytes. (1997) (14)
- Stimulation of left-atrial protein-synthesis rates by increased left-atrial filling pressures in the perfused working rat heart in vitro. (1983) (13)
- Differential rates of protein synthesis in vitro and RNA contents in rat heart ventricular and atrial muscle. (1983) (13)
- PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits. (1999) (12)
- Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active (2011) (12)
- Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. (2008) (10)
- Central effects of morphine and morphine-6-glucuronide on tissue protein synthesis. (1996) (10)
- Acute inhibition of rat heart protein synthesis in vitro during beta-adrenergic stimulation or hypoxia. (1988) (10)
- The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors (2021) (10)
- Mitogen-activated protein kinases are activated by oxidative stress and cytokines in neonatal rat ventricular myocytes. (1997) (10)
- Regulation of Ras z GTP Loading and Ras-Raf Association in Neonatal Rat Ventricular Myocytes by G Protein-coupled Receptor Agonists and Phorbol Ester ACTIVATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE CASCADE BY PHORBOL ESTER IS MEDIATED BY Ras* (1999) (9)
- Effects of pressure overload and insulin on protein turnover in the perfused rat heart. Prostaglandins are not involved although their synthesis is stimulated by insulin. (1987) (9)
- Effect of insulin and lack of effect of workload and hypoxia on protein degradation in the perfused working rat heart. (1983) (9)
- Effects of vasopressin, glucagon and dibutyryl cyclic AMP on the activities of enzymes of fatty acid esterification in rat hepatocytes (1980) (9)
- The effects of glucose, acetate, lactate and insulin on protein degradation in the perfused rat heart. (1982) (8)
- Integration of protein kinase signaling pathways in cardiac myocytes: signaling to and from the extracellular signal-regulated kinases. (2004) (7)
- ERK 1 / 2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes (2017) (7)
- Phosphorylation c-Jun and ATF2 in ventricular myocytes by endothelin and phenylephrine. (1997) (6)
- Tissue Expression of Endothelin-1 Mrna in Endotoxaemia (1995) (6)
- The anti-cancer drug dabrafenib is not cardiotoxic and inhibits cardiac remodelling and fibrosis in a murine model of hypertension. (2021) (6)
- Rates of synthesis of actomyosin in atria and ventricles of the perfused working rat heart. (1985) (6)
- Control of Metabolic Processes by cAMP-Dependent Protein Phosphorylation (1976) (6)
- Regulation of pyruvate dehydrogenase by insulin action. (1979) (6)
- Cell stresses regulate the phosphorylation state of c-Jun and ATF2 in ventricular myocytes. (1997) (5)
- Subcellular mechanism of the species difference in the contractile response of ventricular myocytes to endothelin-1. (1993) (5)
- MAP4K4 expression in cardiomyocytes: multiple isoforms, multiple phosphorylations and interactions with striatins (2021) (5)
- Feedback regulation by Atf 3 in the endothelin-1-responsive transcriptome of cardiomyocytes : Egr 1 is a principal Atf 3 target (2012) (5)
- Endothelin-1 regulation of immediate early gene expression in cardiac myocytes: negative feedback regulation of interleukin 6 by Atf3 and Klf2. (2009) (5)
- Actions and interactions of AMPK with insulin, the peroxisomal-proliferator activated receptors and sirtuins (2012) (5)
- Mitogen-activated protein (MAP) kinase stimulation by phorbol esters and external load in the isolated perfused heart. (1993) (4)
- Morphological and molecular effects of clenbuterol on cardiac myocytes - role of IGF-I (2004) (4)
- Serum cholesterol, triglycerides, and aggression (1992) (4)
- Regulation of BCL-2 Family Proteins during Development and in Response to Oxidative Stress-Induced Cardiac Myocyte Apoptosis. Association with Changes in Mitochondrial Membrane Potential (2000) (4)
- Metabolism of aromatic amino acids by the rat heart and diaphragm (1980) (4)
- Cardiac myocytes and the cardiac action potential (2010) (4)
- Down-regulation of protein kinase C isotypes during postnatal development of rat heart. (1993) (4)
- Acidic fibroblast growth factor or endothelin-1 stimulate the MAP kinase cascade in cardiac myocytes. (1993) (3)
- The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes. (2013) (3)
- Stimulation of atrial natriuretic factor promoter activity by Src and Ras in cultured neonatal rat ventricular myocytes. (1995) (3)
- Regulation of gene and protein expression in cardiac myocyte hypertrophy and apoptosis. (2005) (3)
- 1030-11 Ventricular Myocytes in Culture Express Endothelin-1 (ET-1) mRNA but not ET-2 mRNA or ET-3 mRNA in Response to the Hypertrophic Agonists Phenylephrine and ET-1 (1995) (3)
- Chemotherapeutic agents and gene expression in cardiac myocytes. (2007) (2)
- Corrigendum to “Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active” [Cell Signal 23 (2011) 468–477] (2011) (2)
- Activation of mitogen-activated protein kinase subfamilies by oxidative stress in the perfused rat heart. (1997) (2)
- Lactate utilization by the heart in vivo. (1993) (2)
- Serum cholesterol, triglycerides, and aggression. (1992) (2)
- Dying by the way you live: AIF vs. caspases in apoptosis of hypertrophied cardiomyocytes. (2010) (2)
- The effects of the exogenous provision of lactate and the endogenous production of lactate on protein synthesis in the heart. (1992) (2)
- P95Effects of dabrafenib and trametinib, cancer therapies that target BRaf and MEK, on cardiac signalling (2014) (1)
- Clerk and Sugden Small ( 21 kDa ) G Proteins and Cardiac Hypertrophy (2000) (1)
- Redox regulation of cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) controls p38-MAPK (Mitogen-Activated Protein Kinase) and orchestrates cardiac remodelling to hypertension cardiac ASK1 (Apoptosis Signal-Regulating Kinase 1) controls p38-MAPK (Mitogen-Activated Protein Kinase) and orchestrates (2020) (1)
- 164 Effects of Dabrafenib and Trametinib, Cancer Therapies that Target Braf and MEK, on Cardiac Signalling (2014) (1)
- Intracellular Signaling Through Protein Kinases in Cardiac Mechanotransduction (2007) (1)
- Stimulation of cardiac protein synthesis by insulin-like growth factors. (1991) (1)
- The insulin receptor family in the heart: new light on old insights (2022) (1)
- Effects of hypoxia on protein synthesis in rat heart and skeletal muscle (1985) (1)
- LIFE EXTENSION IN HEART DISEASE (1986) (1)
- Rat liver protein synthesis after partial hepatectomy. (1989) (1)
- Activities of cathepsins B, D, H and L in rat heart atrial and ventricular muscle. (1984) (1)
- Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice (2022) (1)
- Protein turnover in the in vitro perfused working rat heart. (1984) (1)
- Abstract 443: α 1 -adrenergic Receptor Agonists Activate Akt Signalling via the Insulin Receptor Family of Receptors (2018) (0)
- Abstract 470: Raf Kinase Inhibitors Activate ERK1/2 in Cardiomyocytes, Promoting Cardiac Hypertrophy in vitro and, in the Context of Angiotensin II-Induced Hypertension in Mice, in vivo (2017) (0)
- 8 Expression and Activity of Braf in Cardiomyocytes (2014) (0)
- O.49 Whole-body protein synthesis is depressed by anaesthesia (1983) (0)
- Cardiac physiology (2020) (0)
- Regulation of the expression of ATF3 in cardiac myocytes in response to hypertrophic and apoptotic stimulation (2007) (0)
- Cultured Ventricular Myocytes Express Endothelin-1 (Et-1) Mrna but Not Et-2 Mrna Or Et-3 Mrna in Response to the Hypertrophic Agonists Phenylephrine and Et-1 (1995) (0)
- CLONING AND CHARACTERISATION OF A 1233-RESIDUE MITOGEN-ACTIVATED KINASE KINASE KINASE KINASE 4 (MAP4K4) FROM RAT CARDIOMYOCYTES (2014) (0)
- Effects of catecholamines on protein synthesis and cyclic AMP concentrations in the isolated working heart. (1991) (0)
- Mortality After Myocardial Infarction Conditional Transgenic Expression of Fibroblast Growth Factor 9 in the Adult Mouse (2011) (0)
- Theeffects ofcalcium ions, ionophore A23187andinhibition ofenergy metabolism on protein degradation intheratdiaphragm andepitrochlearis muscles invitro (1980) (0)
- Abstract 16383: Inhibition of Egfr Signalling Promotes Maladaptive Cardiac Remodelling in Hypertensive Heart Disease (2020) (0)
- Acute alpha1-adrenergic stimulation enhances protein synthesis and raises intracellular pH in anterogradely-perfused rat hearts (1990) (0)
- Liposomal Transfection of Cultured Cardiac Myocytes with Antisense Oligodeoxynucleotides (1995) (0)
- Alterations in signal transduction (2005) (0)
- Brief Communication Phenylephrine and endothelin-1 upregulate connective tissue growth factor in neonatal rat cardiac myocytes (2004) (0)
- Intracellular signaling during myocardial ischemia (2007) (0)
- Theeffects ofglucose, acetate, lactate andinsulin onprotein degradation in theperfused ratheart (1982) (0)
- Effects of starvation on protein turnover in the rat heart in vivo and invitro (1984) (0)
- Regulation by Metabolites of Inactivating and Additional Phosphorylation Reactions in the Pig Heart Pyruvate Dehydrogenase Complex (1979) (0)
- Abstract 491: Cardiomyocyte Braf Promotes Hypertrophy and is Required for Hypertrophic Adaptation to Hypertension in Mice In Vivo, but Raf Inhibitors Have Differential Effects (2018) (0)
- 85 Enhanced nuclear RSK1 signalling promotes cardiac hypertrophy in mice in vivo, but compromises compensated hypertrophy induced by phenylephrine (2018) (0)
- Effects of endothelin-1 on contractile responses and phosphatidylinositol hydrolysis in isolated myocytes from guinea-pig and rat heart (1992) (0)
- 228 Braf inhibitors, sb590885 and dabrafenib, enhance erk1/2 signalling in cardiomyocytes and promote cardiac hypertrophy (2017) (0)
- Effects of pregnancy on agonist-stimulated PI hydrolysis in cardiomyocytes. (1993) (0)
- DISSECTING THE ROLES OF MITOGEN-ACTIVATED PROTEIN KINASE (MAPK) CASCADES IN THE MRNA EXPRESSION RESPONSE TO H2O2 IN CARDIOMYOCYTES (2014) (0)
- Rates of protein synthesis in rat hearts in vivo and in vitro (1984) (0)
- 227 IDENTIFYING THE PROTEIN KINASES IN THE CARDIAC MYOCYTE KINOME (2013) (0)
- Great Britain The Apparent Inhibition of Phosphofructokinase by Reduced Nicotinamide-Adenine Dinucleotide : a Problem of Coupled-Enzyme Assays (2005) (0)
- Endothelin Signaling in the Cardiomyocyte (2008) (0)
- 11 Myocardial energetics (2011) (0)
- IS043 MOLECULAR MECHANISMS OF CARDIAC HYPERTROPHY AND SIGNAL TRANSDUCTION (1998) (0)
- The effects of workload on atrial and ventricular protein turnover in the in vitro perfused working rat heart (1983) (0)
- The Effects of Amnonium , Inorganic Phosphate and Potassium Ions on the Activity of Phosphofructokinases from Muscle and Nervous Tissues of Vertebrates and Invertebrates (2005) (0)
- REGULATION OF HEART MUSCLE PYRUVATE DEHYDROGENASE BY PHOSPHORYLATION/DEPHOSPHORYLATION REACTIONS (1978) (0)
- 111 Oxidative stress signalling through ask1 and P38-MAPK regulates cardiomyocyte gene expression and induces hypertrophy (2018) (0)
- Glycogen synthase kinase 3 as a convergence point in hypertrophic signalling (2007) (0)
- DIFFERENTIAL SIGNALLING THROUGH P90 RIBOSOMAL S6 KINASES (RSKS) TO CARDIOMYOCYTE GENE EXPRESSION BY ENDOTHELIN-1 VERSUS α-ADRENERGIC AGONISTS (2012) (0)
- 160 Cardiac dysfunction in mice with reduced striatin expression (2017) (0)
- The effects of hormonal factors on cardiac protein turnover. (1985) (0)
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What Schools Are Affiliated With Peter H. Sugden?
Peter H. Sugden is affiliated with the following schools:
