Peter J. Meier
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Chemistry Biology
Peter J. Meier's Degrees
- PhD Biochemistry University of California, San Francisco
- Masters Chemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)Peter J. Meier's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties (2004) (988)
- The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver* (1998) (950)
- The superfamily of organic anion transporting polypeptides. (2003) (847)
- Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. (2001) (740)
- Molecular pathogenesis of cholestasis. (2012) (724)
- Enterohepatic bile salt transporters in normal physiology and liver disease. (2004) (597)
- St John's Wort induces intestinal P‐glycoprotein/MDR1 and intestinal and hepatic CYP3A4 (2000) (586)
- Bile salt transporters. (2002) (551)
- Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. (2000) (545)
- Expression cloning of a rat liver Na(+)-independent organic anion transporter. (1994) (539)
- The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: A potential mechanism for hepatic adverse reactions (2001) (473)
- Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin. (2005) (459)
- Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. (1991) (453)
- Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. (1994) (423)
- Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. (1995) (420)
- Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. (1997) (409)
- Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier. (2000) (395)
- Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver (1997) (363)
- Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver (2002) (362)
- Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver (1984) (362)
- Expression of members of the multidrug resistance protein family in human term placenta. (2000) (317)
- Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury (2007) (300)
- Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter. (2002) (298)
- Epidemiology of drug exposure and adverse drug reactions in two swiss departments of internal medicine. (2000) (292)
- Localization of the Organic Anion Transporting Polypeptide 2 (Oatp2) in Capillary Endothelium and Choroid Plexus Epithelium of Rat Brain (1999) (290)
- Hepatic transport of bile salts. (2000) (288)
- Hepatobiliary transporters and drug‐induced cholestasis (2006) (277)
- Identification of Glutathione as a Driving Force and Leukotriene C4 as a Substrate for oatp1, the Hepatic Sinusoidal Organic Solute Transporter* (1998) (275)
- Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver. (2001) (256)
- Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy. (2004) (255)
- Characterization of inducible nature of MRP3 in rat liver. (2000) (253)
- Functional expression of the canalicular bile salt export pump of human liver. (2002) (248)
- Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. (2000) (246)
- In situ localization of the hepatocytic Na+/Taurocholate cotransporting polypeptide in rat liver. (1994) (239)
- Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. (1999) (233)
- Transport function and hepatocellular localization of mrp6 in rat liver. (2000) (227)
- Oatp2 mediates bidirectional organic solute transport: a role for intracellular glutathione. (2000) (226)
- Hepatic uptake of the magnetic resonance imaging contrast agent gadoxetate by the organic anion transporting polypeptide Oatp1. (1999) (225)
- Drug uptake systems in liver and kidney. (2003) (222)
- Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver. (1999) (222)
- Interindividual variability of canalicular ATP‐binding‐cassette (ABC)–transporter expression in human liver (2006) (221)
- The bile salt export pump (2007) (214)
- Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes. (1994) (201)
- Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier. (1984) (199)
- Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile. (1995) (190)
- Incidence of drug-induced liver injury in medical inpatients (2005) (187)
- Identification of thyroid hormone transporters. (1999) (182)
- Immunologic distribution of an organic anion transport protein in rat liver and kidney. (1996) (180)
- Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3 (2001) (179)
- Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier (2001) (179)
- Enterohepatic transport of bile salts and genetics of cholestasis. (2005) (178)
- Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta. (2002) (175)
- BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis (2004) (174)
- Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters. (2009) (174)
- Transport of bile acids in hepatic and non-hepatic tissues. (2001) (168)
- Characterization of the Human OATP-C (SLC21A6) Gene Promoter and Regulation of Liver-specific OATP Genes by Hepatocyte Nuclear Factor 1α* (2001) (165)
- Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump. (2008) (165)
- Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas. (1997) (163)
- Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor. (2002) (157)
- Functional characterization of the basolateral rat liver organic anion transporting polypeptide (1994) (155)
- P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the Hepatobiliary Disposition of a Model Opioid Peptide (2004) (153)
- Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells. (1999) (151)
- Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full‐length isoform of the liver‐specific transporter‐1 (rlst‐1) in rat liver (2000) (150)
- Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. (1991) (150)
- Identification of steroid sulfate transport processes in the human mammary gland. (2003) (149)
- Molecular regulation of hepatocellular transport systems in cholestasis. (1999) (147)
- Hepatic transport systems regulating pHi, cell volume, and bile secretion. (1992) (143)
- The choroid plexus epithelium is the site of the organic anion transport protein in the brain. (1997) (138)
- Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis. (2005) (138)
- Multispecific amphipathic substrate transport by an organic anion transporter of human liver. (1996) (138)
- Sinusoidal (basolateral) bile salt uptake systems of hepatocytes. (1996) (136)
- ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles. (1992) (136)
- Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver. (1993) (134)
- Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells. (2002) (133)
- REVERSAL OF HEPATIC COMA BY BENZODIAZEPINE ANTAGONIST (Ro 15-1788) (1985) (132)
- Multiple Factors Regulate the Rat Liver Basolateral Sodium-dependent Bile Acid Cotransporter Gene Promoter* (1996) (130)
- Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. (1996) (128)
- Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain. (2007) (127)
- Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain (1998) (124)
- Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes (2001) (118)
- Comparative Inhibitory Effects of Different Compounds on Rat Oatp1 (Slc21a1)- and Oatp2 (Slc21a5)-Mediated Transport (2002) (114)
- Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver (2001) (110)
- Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene. (2004) (110)
- The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3beta in hepatocellular carcinoma. (2004) (108)
- Evidence for carrier-mediated chloride/bicarbonate exchange in canalicular rat liver plasma membrane vesicles. (1985) (105)
- Parallel decrease of Na+ ‐taurocholate cotransport and its encoding mRNA in primary cultures of rat hepatocytes (1993) (104)
- Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2. (2004) (103)
- Substrate specificity of the rat liver Na+-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells. (1998) (102)
- Functional expression of the rat liver canalicular isoform of the multidrug resistance‐associated protein (1997) (101)
- Characterization of the mouse bile salt export pump overexpressed in the baculovirus system (2001) (101)
- Genetic determinants of drug-induced cholestasis and intrahepatic cholestasis of pregnancy. (2010) (101)
- Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides. (2001) (101)
- Stable Inducible Expression of a Functional Rat Liver Organic Anion Transport Protein in HeLa Cells (*) (1995) (99)
- Effects of the benzodiazepine receptor antagonist flumazenil in hepatic encephalopathy in humans. (1989) (98)
- Organic anion transport across the choroid plexus (2001) (97)
- Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations. (1999) (96)
- alpha-Amanitin uptake into hepatocytes. Identification of hepatic membrane transport systems used by amatoxins. (1986) (96)
- Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver. (1999) (96)
- Isolation and characterization of rough endoplasmic reticulum associated with mitochondria from normal rat liver. (1981) (96)
- Expression of the hepatocyte Na+/bile acid cotransporter in Xenopus laevis oocytes. (1990) (95)
- Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2 (2000) (95)
- Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride. (2002) (95)
- Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles. (1989) (93)
- Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium. (2005) (91)
- Metal‐responsive transcription factor‐1 (MTF‐1) is essential for embryonic liver development and heavy metal detoxification in the adult liver (2004) (89)
- Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin (2001) (87)
- Hepatic Monooxygenase Activities in Subjects With a Genetic Defect in Drug Oxidation (1983) (85)
- Insulin regulates the expression of the insulin-like growth factor binding protein 2 mRNA in rat hepatocytes. (1990) (84)
- The Human Organic Anion Transporter 2 Gene Is Transactivated by Hepatocyte Nuclear Factor-4α and Suppressed by Bile Acids (2005) (83)
- Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. (2002) (83)
- Regulation of basolateral organic anion transporters in ethinylestradiol-induced cholestasis in the rat. (2003) (83)
- Hepatocellular transporters and cholestasis. (2005) (83)
- Linkage between a new splicing site mutation in the MDR3 alias ABCB4 gene and intrahepatic cholestasis of pregnancy (2007) (82)
- Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy. (2002) (82)
- Partial Maintenance of Taurocholate Uptake by Adult Rat Hepatocytes Cultured in a Collagen Sandwich Configuration (1998) (81)
- Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene (1997) (79)
- Transport polarity of hepatocytes. (1988) (79)
- Phylogenic and ontogenic expression of hepatocellular bile acid transport. (1993) (78)
- Dose-dependent toxicity of diphenhydramine overdose (2000) (78)
- Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptide. (1998) (76)
- Isolation and characterization of the putative canalicular bile salt transport system of rat liver. (1987) (75)
- Preparation of basolateral (sinusoidal) and canalicular plasma membrane vesicles for the study of hepatic transport processes. (1990) (75)
- Mechanisms of cholestasis. (2000) (74)
- Expression of rat renal sulfate transport systems in Xenopus laevis oocytes. Functional characterization and molecular identification. (1994) (74)
- Functional Analysis of the Extracellular Cysteine Residues in the Human Organic Anion Transporting Polypeptide, OATP2B1 (2006) (73)
- Uptake of the mycotoxin ochratoxin A in liver cells occurs via the cloned organic anion transporting polypeptide. (1996) (71)
- Adverse drug events caused by medication errors in medical inpatients. (2004) (70)
- Gender Difference in the Urinary Excretion of Organic Anions in Rats (2002) (70)
- Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS (2015) (70)
- Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier. (2001) (69)
- Evidence for the presence of a phosphatidylcholine translocator in isolated rat liver canalicular plasma membrane vesicles. (1993) (69)
- Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat. (2004) (68)
- Transport of xenobiotics across the blood-brain barrier. (2002) (68)
- cAMP increases liver Na+-taurocholate cotransport by translocating transporter to plasma membranes. (1997) (68)
- Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver. (2001) (65)
- Bile acid and xenobiotic transporters in liver. (1998) (64)
- Differential expression of bile salt and organic anion transporters in developing rat liver. (2004) (64)
- Rat hepatocytes exhibit basolateral Na+/HCO3- cotransport. (1989) (63)
- Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate (1998) (63)
- Functional reconstitution of the canalicular bile salt transport system of rat liver. (1988) (61)
- The peptide‐based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion‐transporting polypeptide (1996) (61)
- Differential interaction of bile acids from patients with inborn errors of bile acid synthesis with hepatocellular bile acid transporters. (1997) (61)
- Coordinate transcriptional regulation of transport and metabolism. (2005) (59)
- Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. (2005) (58)
- ABC‐transporters are localized in caveolin‐1‐positive and reggie‐1‐negative and reggie‐2‐negative microdomains of the canalicular membrane in rat hepatocytes (2009) (58)
- Hepatocellular transport of bile acids. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes. (1994) (57)
- Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. (2001) (56)
- Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes. (2004) (56)
- Regulation of rat organic anion transporters in bile salt‐induced cholestatic hepatitis: Effect of ursodeoxycholate (2003) (56)
- Effect of Ursodeoxycholic Acid on the Impairment Induced by Maternal Cholestasis in the Rat Placenta-Maternal Liver Tandem Excretory Pathway (2003) (56)
- Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells. (1994) (56)
- Localization of organic anion transport protein 2 in the apical region of rat retinal pigment epithelium. (2002) (55)
- Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocytes. (1989) (55)
- Expression of the hepatocellular chloride-dependent sulfobromophthalein uptake system in Xenopus laevis oocytes. (1991) (54)
- Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity. (1995) (54)
- Na-H exchange in rat liver basolateral but not canalicular plasma membrane vesicles. (1986) (54)
- Bile acids modulate the interferon signalling pathway (1999) (54)
- Effect of obstructive cholestasis on membrane traffic and domain‐specific expression of plasma membrane proteins in rat liver parenchmal cells (1994) (53)
- Properties of the canalicular bile acid transport system in rat liver. (1987) (53)
- Regulation of Bile Salt Export Pump mRNA Levels by Dexamethasone and Osmolarity in Cultured Rat Hepatocytes (1999) (52)
- Regulation of hepatocyte bile salt transporters during hepatic regeneration. (1997) (52)
- Magnetic Resonance Imaging With Hepatospecific Contrast Agents in Cirrhotic Rat Livers (2005) (52)
- Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication. (1995) (51)
- Differential effects of microsomal enzyme–inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2 (2001) (51)
- Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver. (2003) (50)
- Hepatic monooxygenase activities in subjects with a genetic defect in drug oxidation. (1983) (50)
- Identification and localization of sodium-phosphate cotransporters in hepatocytes and cholangiocytes of rat liver. (2005) (49)
- Multispecific anion exchange in basolateral (sinusoidal) rat liver plasma membrane vesicles. (1986) (48)
- Functional analysis of the rat bile salt export pump gene promoter. (2002) (48)
- Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells (2000) (47)
- Fatal liver failure with atorvastatin. (2003) (44)
- Differential regulation of insulin‐like growth factor binding protein (IGFBP)‐2 mRNA in liver and bone cells by insulin and retinoic acid in vitro (1992) (44)
- Characterization of the transport properties of organic anion transporting polypeptide 1 (oatp1) and Na(+)/taurocholate cotransporting polypeptide (Ntcp): comparative studies on the inhibitory effect of their possible substrates in hepatocytes and cDNA-transfected COS-7 cells. (2000) (43)
- Gender difference in the Oatp1-mediated tubular reabsorption of estradiol 17beta-D-glucuronide in rats. (2002) (43)
- Bufuralol metabolism in human liver: a sensitive probe for the debrisoquine‐type polymorphism of drug oxidation (1984) (41)
- The effect of changes in the fluid state of rat liver plasma membrane on the transport of taurocholate (1987) (41)
- Direct energization of bile acid transport into plant vacuoles. (1993) (40)
- Functional characterization of the mouse organic-anion-transporting polypeptide 2. (2002) (39)
- Expression and Functional Involvement of Organic Anion Transporting Polypeptide Subtype 3 (Slc21a7) in Rat Choroid Plexus (2003) (39)
- Isolation of a subfraction of rough endoplasmic reticulum closely associated with mitochondria. Evidence for its role in cytochrome P450 synthesis. (1978) (38)
- Pharmacogenetics of hepatocellular transporters. (2003) (36)
- Identification of a single sinusoidal bile salt uptake system in skate liver. (1987) (35)
- Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice. (1999) (35)
- Demonstration of a transcellular vesicle pathway for biliary excretion of inulin in rat liver. (1986) (34)
- Pharmacogenetics of drug transporters in the enterohepatic circulation. (2011) (34)
- Small hepatocytes in culture develop polarized transporter expression and differentiation (2004) (34)
- Characterizing mechanisms of hepatic bile acid transport utilizing isolated membrane vesicles. (1990) (33)
- No clinically relevant effect of Iornoxicam intake on acenocoumarol pharmacokinetics and pharmacodynamics (1999) (33)
- Molecular Mechanisms in Bile Formation. (2000) (33)
- The bile salt secretory polarity of hepatocytes. (1989) (31)
- Phenobarbital alters hepatic Mrp2 function by direct and indirect interactions. (2003) (31)
- Transport mechanisms for cationic drugs and proteins in kidney, liver and intestine: implication for drug interactions and cell-specific drug delivery. (1999) (29)
- CHARACTERIZATION OF TWO SPLICE VARIANTS OF HUMAN ORGANIC ANION TRANSPORTING POLYPEPTIDE 3 A 1 ( OATP 3 A 1 ) ISOLATED FROM HUMAN BRAIN (2006) (27)
- Bicarbonate sulfate exchange in canalicular rat liver plasma membrane vesicles. (1987) (27)
- Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization. (1996) (27)
- Functional analysis and androgen-regulated expression of mouse organic anion transporting polypeptide 1 (Oatp1) in the kidney. (2001) (27)
- Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates. (2005) (26)
- Gd-BOPTA Transport Into Rat Hepatocytes: Pharmacokinetic Analysis of Dynamic Magnetic Resonance Images Using a Hollow-Fiber Bioreactor (2004) (26)
- Hepatic bile salt flux does not modulate level and activity of the sinusoidal Na+-taurocholate cotransporter (ntcp) in rats. (1997) (25)
- Cholate uptake in basolateral rat liver plasma membrane vesicles and in liposomes. (1990) (25)
- Identification and characterization of a basolateral dicarboxylate/cholate antiport system in rat hepatocytes. (1995) (25)
- Functional analysis of candidate ABC transporter proteins for sitosterol transport. (2002) (24)
- Anion transport in basolateral (sinusoidal) liver plasma-membrane vesicles of the little skate (Raja erinacea). (1987) (23)
- No clinically relevant drug interaction between paracetamol and phenprocoumon based on a pharmacoepidemiological cohort study in medical inpatients (2002) (21)
- Hepatocellular transport systems: from carrier identification in membrane vesicles to cloned proteins. (1996) (21)
- Taurocholate induces preferential release of phosphatidylcholine from rat liver canalicular vesicles. (2008) (21)
- Drug reimbursement: indicators of inappropriate resource allocation. (2002) (20)
- Mechanism and subcellular site of bilirubin diglucuronide formation in rat liver. (1984) (19)
- Physiological characteristics of allo-cholic acid11 Part of this work has appeared in abstract form in Gastroenterol. Hepatol. 2000. 23: 131. Published, JLR Papers in Press, September 1, 2002. DOI 10.1194/jlr.M200220-JLR200 (2003) (19)
- Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide (1987) (18)
- Expression of a rat liver phosphatidylcholine translocator in Xenopus laevis oocytes (1996) (18)
- cAMP increases liver Na+-taurocholate cotransport by translocating transporter to plasma membranes. (1997) (15)
- ATP-dependent Ca2+ uptake and Ca2+-dependent protein phosphorylation in basolateral liver plasma membranes. (1988) (15)
- Opposite effects of lornoxicam co-administration on phenprocoumon pharmacokinetics and pharmacodynamics (1999) (14)
- Na+-Dependent and Na+-Independent Bile Acid Uptake Systems in the Liver (1994) (14)
- Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells. (1998) (14)
- Canalicular membrane adenosine triphosphate-dependent transport systems. (1993) (13)
- Safety of liver donation after fatal intoxication with the tricyclic antidepressant trimipramine. (1996) (13)
- Canalicular bile formation: beyond single transporter functions. (2002) (11)
- Biosynthesis of rat liver cytochrome P-450 in mitochondria-associated rough endoplasmic reticulum and in rough microsomes in vivo. (1984) (11)
- Carrier-mediated hepatic uptake of peptidic endothelin antagonists in rats. (1999) (11)
- Hepatocellular transport proteins and their role in liver disease. (2001) (11)
- Differential regulation of basolateral and canalicular transporter expression in rat liver in chronic renal failure (2005) (10)
- Solvent isotope effect on bile formation in the rat. (1995) (10)
- Effects of the Benzodiazepine Receptor Antagonist Flumazenil in Hepatic Encephalopathy in Humans (1990) (10)
- Hepatocyte transplantation: potential of hepatocyte progenitor cells and bone marrow derived stem cells. (2006) (10)
- Hepatocyte performance on different crystallographic faces of rutile. (2003) (10)
- Expression of sodium-independent organic anion uptake systems of skate liver in Xenopus laevis oocytes. (1995) (10)
- No effect of garlic extract on saquinavir kinetics and hepatic CYP3A4 function measured by the erythromycin breath test (2004) (8)
- Pyridoxine-responsive primary acquired sideroblastic anaemia. In vitro and in vivo effects of vitamin B6 on decreased 5-aminolaevulinate synthase activity. (2009) (8)
- [Benzodiazepine--practice and problems of its use]. (1988) (7)
- Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects. (1980) (7)
- Surveillance of occupational illness through a national poison control center: an approach to reach small-scale enterprises? (1994) (7)
- [Acquired, vitamin B6-responsive, primary sideroblastic anemia, an enzyme deficiency in heme synthesis]. (1981) (7)
- Separation of hepatocyte plasma membrane domains by free flow electrophoresis. (1989) (6)
- Organic anion transporting polypeptides, cholestasis, and nuclear receptors (2002) (6)
- Bile duct ligation-induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantitation (2004) (6)
- Identification of sodium-dependent and sodium-independent dicarboxylate transport systems in rat liver basolateral membrane vesicles (1992) (6)
- Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS (2014) (6)
- Uptake of 3 alpha, 7 alpha, 12 alpha-trihydroxy-24-nor-5 beta-cholan-23-sulfonate into isolated rat hepatocytes by three transport systems. (1997) (5)
- The effect of ethanol and calcium on fluid state of plasma membranes of rat hepatocytes. (1985) (5)
- Advances in hepatic transport: Molecular mechanisms, genetic disorders, and treatment. A summary of the 1998 AASLD single topic conference (1998) (5)
- Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells. (1999) (4)
- Cardiovascular drug utilization and its determinants in unselected medical patients with ischemic heart disease. (2002) (4)
- Polar surface distribution of type II insulin-like growth factor receptor in rat hepatocytes (1990) (4)
- Effects Of The Benzodiazepine Antagonist Flumazenil In Hepatic Encephalopathy in Man (1989) (4)
- Transport of organic cations by the rat organic anion transporting polypeptides oatp1, oatp2 and the human OATP. (1998) (4)
- Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. (1999) (4)
- 743 BSEP and MDR3 sequence diversity and haplotype structure in primary sclerosing cholangitis and primary biliary cirrhosis (2003) (3)
- P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the (2004) (3)
- Differentiation of Non-Adherent Hematopoietic Stem Cells from Umbilical Cord Blood Cells into Adherent Hepatocytic Lineage. (2006) (2)
- Driving Forces for Taurocholate Transport across Basolateral and Canalicular Rat Liver Plasma Membrane Vesicles (1984) (2)
- [Clinico-pharmacological case (2). Bradycardia and ventricular tachycardia of the torsades de pointes type as a side effect of vasopressin: 3 case reports]. (1996) (2)
- Uptake of 3α,7α, 12α-trihydroxy-24-nor-5β-cholan- 23-sulfonate into isolated rat hepatocytes by three transport systems (1997) (2)
- Hormonal regulation of insulin-like growth factor binding proteins from culturd rat hepatocytes and osteoblasts (1989) (2)
- Organ and cellular distribution of the organic anion transporting polypeptide 2 (oatp2) in rat (1998) (2)
- [Drug therapy in liver disease]. (1982) (2)
- [Current possibilities in the therapy of hepatic encephalopathy]. (1990) (1)
- STRUCTURAL AND FUNCTIONAL INTERACTION OF ROUGH ENDOPLASMIC RETICULUM (RER) AND MITOCHONDRIA DURING SYNTHESIS OF HEPATIC CYTOCHROME P450 (1977) (1)
- Hepatocyte transplantation: potential of hepatocyte progenitor cells and bone marrow derived stem cells. (2006) (1)
- [Clinically significant inherited differences in the mode of action of drugs]. (1982) (1)
- Pharmacokinetics of high doses of intramuscular and oral heroin in narcotic addicts (2004) (1)
- [Acute poisoning with thioridazine]. (1996) (1)
- [Poisoning with drugs, household products and plants in the case load of the Swiss Toxicologic Information Center]. (1992) (1)
- Transport of the liver specific MRI-contrast agent Gd-EOB-DTPA by the rat organic anion transporting polypeptide OATP1. (1998) (1)
- [Role of nuclear receptors in hepatic and intestinal drug transport]. (2003) (1)
- Expression cloning of the hepatocyte Na+/bile acid cotransport system (1991) (1)
- Identification and characterization of rat Oatp4, a multispecificorganic anion transporting polypeptide that is closely related torlst-1 (2000) (1)
- Significance of Hepatobiliary Transporters for Drug-Induced Liver Disease (2007) (0)
- BSEP and MDR3 sequence diversity and haplotype structure in primary sclerosing cholangitis, primary biliary cirrhosis and intrahepatic cholestasis of pregnancy (2004) (0)
- Expression of hepatocellular transporters in long-term cultured small hepatocytes (2001) (0)
- 461 Transcriptional regulation of the human, mouse and rat NTCP/NTCP genes: role of liver enriched transcription factors (2003) (0)
- Physiological characteristics of allo -cholic acid 1 (2002) (0)
- Hepatocellular Transport Systems: Basolateral Membrane (2004) (0)
- Quick lock clock data recovery for Phase Steps (2012) (0)
- nterohepatic Bile Salt Transporters in Normal Physiology and iver Disease (0)
- [Alcohol, alcoholism and drugs]. (1985) (0)
- 458 The human organic anion transporting polypeptide 8 gene (OATP8) is transactivated by the xenobiotics rifampicin and phenobarbital through an FXR-mediated mechanism (2003) (0)
- ABC-Transporters are localized in Caveolin-1 positive and Reggie-1 and-2 negative Microdomains of the Canalicular Membrane in Rat Hepatocytes (2009) (0)
- [Aspirin against aging? For whom and how much?]. (1990) (0)
- Contents, Vol. 4, 1994 (1994) (0)
- Transport properties of the canalicular bile salt transporter or sister of P-glycoprotein (1998) (0)
- 3 2 DRUG UPTAKE SYSTEMS IN LIVER AND KIDNEY (2001) (0)
- transporter Oatp1 in stably transfected CHO cells Polyspecific substrate uptake by the hepatic organic anion (2016) (0)
- Already published in CDM) Drug Uptake Systems in Liver and Kidney (2004) (0)
- Expression of the canalicular sulfate transport system in Xenopus laevis oocytes (1990) (0)
- Subject Index, Vol. 4, 1994 (1994) (0)
- [Gastrointestinal and hepatic side effects of drugs]. (1987) (0)
- 827 Polarized transport differentiation of small heptocytes in culture (2003) (0)
- Pharmacogenomics of Cholestatic Liver Disease (2005) (0)
- 753 Sequence analysis of BSEP and MDR3 in patients with intrahepatic cholestasis of pregnancy (2003) (0)
- Properties of the Taurocholate Uptake System in Basolateral Rat Liver Plasma Membrane Vesicles: Effects of Albumin and Substrate Specificity (1989) (0)
- Calcium transport in plasma membrane subfractions of rat liver. (1988) (0)
- IN MECHANISMS OF DISEASE Hepatobiliary Transporters and Drug-Induced Cholestasis (2006) (0)
- Transport of Bile Salts Across the Canalicular Plasma Membrane (1989) (0)
- 1 Physiology of bile formation: Hepatocellular bile salt transporters (2012) (0)
- 457 Identification of sodium/phosphate contransporter type IIB (NAPI-IIB) in the canalicular plasma membrane of rat hepatocytes (2003) (0)
- Differential ontogenic expression of bile acid and organic anion transporters in the rat liver (2001) (0)
- Substrate specificity of the rat organic anion transporting polypeptides oapt1, oatp2 and the human OATP (1999) (0)
- Hepatocellular uptake of organic cations by the organic anion transporting polypeptides (Oatp1, Oatp2 and OATP-A) and the organic cation transporters (rOCT1 and hOCT1) (2000) (0)
- [Drug therapy of pain]. (1989) (0)
- Immunogold qantification of the canalicular bile salt transporting protein (cBSTP) in normal and bile duct ligated rat hepatocyte plasma membranes (1989) (0)
- Functional characterization of MDR3 promoter mutations detected in intrahepatic cholestasis of pregnancy (2004) (0)
- Uptake of 3 a , 7 a , 1 2 a-trihydroxy-24-nor-5 g-cholan-23-sulfonate into isolated rat hepatocytes by three transport systems (2002) (0)
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