Philippe Kourilsky

Philippe Kourilsky's AcademicInfluence.com Rankings

Philippe Kourilsky

Biology

#7953

World Rank

#10954

Historical Rank

Immunology

#435

World Rank

#452

Historical Rank

biology Degrees

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Biology

Philippe Kourilsky's Degrees

PhD Immunology Université Paris Cité
Doctorate Medicine Université Paris Cité

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Philippe Kourilsky's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets. (2011) (843)
A Direct Estimate of the Human αβ T Cell Receptor Diversity (1999) (828)
The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product (1990) (795)
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. (1993) (722)
Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells1 (2004) (720)
T-cell repertoire diversity and clonal expansions in normal and clinical samples. (1995) (612)
A new dominant hybrid selective marker for higher eukaryotic cells. (1981) (531)
A direct estimate of the human alphabeta T cell receptor diversity. (1999) (493)
Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion. (2000) (411)
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire (1991) (358)
NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats (1992) (352)
Optimal conditions for directly sequencing double-stranded PCR products with sequenase (1990) (342)
Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression (1986) (314)
Expanded CD4+ and CD8+ T cell clones in elderly humans. (1997) (306)
Implication of γδ T cells in the human immune response to cytomegalovirus (1999) (304)
IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity (2009) (276)
Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection (1998) (273)
The characterization of the promoter of the gene encoding the p50 subunit of NF‐kappa B indicates that it participates in its own regulation. (1992) (264)
TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B‐like enhancer binding activity which displaces constitutive factors. (1989) (264)
Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. (1994) (261)
Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants. (1992) (246)
Size Estimate of the αβ TCR Repertoire of Naive Mouse Splenocytes1 (2000) (243)
Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires. (1998) (235)
Systems medicine and integrated care to combat chronic noncommunicable diseases (2011) (230)
Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice (1994) (225)
The regulation and expression of MHC class I genes. (1990) (225)
Differential cytokine expression in maternal blood and placenta during murine gestation. (1994) (202)
Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls (1999) (193)
Quantitative titration of nucleic acids by enzymatic amplification reactions run to saturation. (1993) (189)
Molecular detection and in vivo analysis of the specific T cell response to a protein antigen (1992) (188)
Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene (1986) (185)
Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless. (1994) (182)
Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12. (1979) (181)
Cytoplasmic retention, DNA binding and processing of the NF‐kappa B p50 precursor are controlled by a small region in its C‐terminus. (1991) (181)
The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct. (2003) (179)
Implication of gammadelta T cells in the human immune response to cytomegalovirus. (1999) (172)
Lineage relationships, homeostasis, and recall capacities of central– and effector–memory CD8 T cells in vivo (2005) (170)
Processing of the precursor of NF-κB by the HIV-1 protease during acute infection (1991) (153)
Most α/β T Cell Receptor Diversity Is Due to Terminal Deoxynucleotidyl Transferase (2001) (144)
Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor. (2000) (141)
CD8 expression allows T cell signaling by monomeric peptide-MHC complexes. (1998) (133)
Cytokine fields and the polarization of the immune response. (2001) (130)
Purification of KBF1, a common factor binding to both H‐2 and beta 2‐microglobulin enhancers. (1987) (129)
Extrathymic T Cell Lymphopoiesis: Ontogeny and Contribution to Gut Intraepithelial Lymphocytes in Athymic and Euthymic Mice (2003) (126)
T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor beta-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases. (1995) (126)
Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells (1994) (125)
Lysogenization by bacteriophage lambda (1973) (123)
Inhibition of transcription factors belonging to the rel/NF‐kappa B family by a transdominant negative mutant. (1991) (122)
Insertion of a rabbit β-globin gene sequence into an E.coli plasmid (1975) (117)
Identical T Cell Clones Are Located within the Mouse Gut Epithelium and Lamina Propria and Circulate in the Thoracic Duct Lymph (2000) (117)
The ovalbumin gene region: common features in the organisation of three genes expressed in chicken oviduct under hormonal control (1979) (117)
A common positive trans-acting factor binds to enhancer sequences in the promoters of mouse H-2 and beta 2-microglobulin genes. (1987) (113)
Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness (1995) (109)
Identification of novel functional differences in monocyte subsets using proteomic and transcriptomic methods. (2009) (107)
Molecular analysis of H-2-deficient lymphoma lines. Distinct defects in biosynthesis and association of MHC class I heavy chains and beta 2-microglobulin observed in cells with increased sensitivity to NK cell lysis. (1989) (107)
Working principles in the immune system implied by the "peptidic self" model. (1987) (107)
Systemic Antitumor Effects of Electrochemotherapy Combined with Histoincompatible Cells Secreting Interleukin‐2 (1995) (105)
Recombinant viruses as a tool for therapeutic vaccination against human cancers. (2000) (103)
Frequent Contribution of T Cell Clonotypes with Public TCR Features to the Chronic Response Against a Dominant EBV-Derived Epitope: Application to Direct Detection of Their Molecular Imprint on the Human Peripheral T Cell Repertoire1 (2000) (101)
The Composition of a Primary T Cell Response Is Largely Determined by the Timing of Recruitment of Individual T Cell Clones (1999) (100)
MHC-antigen interaction: what does the T cell receptor see? (1989) (99)
Combination of MHC-peptide multimer-based T cell sorting with the Immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses. (2002) (96)
Immune response against tumors. (1994) (92)
Retrovirus antigens recognized by cytolytic T lymphocytes activate tumor rejection in vivo (1987) (92)
Graft-infiltrating T helper cells, CD45RC phenotype, and Th1/Th2-related cytokines in donor-specific transfusion-induced tolerance in adult rats. (1995) (92)
In vivo T-cell clonal amplification at time of acute graft-versus-host disease. (1994) (89)
Comparison of nucleotide sequences of mRNAs belonging to the mouse H-2 multigene family. (1982) (87)
Analysis of interleukin 6 gene expression in cervical neoplasia using a quantitative polymerase chain reaction assay: evidence for enhanced interleukin 6 gene expression in invasive carcinoma. (1994) (85)
The Qa‐1b molecule binds to a large subpopulation of murine NK cells (1998) (84)
Expression of class I genes in the major histocompatibility complex: identification of eight distinct mRNAs in DBA/2 mouse liver (1985) (84)
Interleukin 2‐dependent activation of tumor‐specific cytotoxic T lymphocytes in vivo (1991) (84)
Cells expressing a major histocompatibility complex class I molecule with a single covalently bound peptide are highly immunogenic (1995) (82)
Absence of significant H–2 and β2-microglobulin mRNA expression by mouse embryonal carcinoma cells (1982) (81)
Extrathymic T Cell Lymphopoiesis (2003) (78)
Lysogenization by bacteriophage lambda. III. Multiplicity dependent phenomena occuring upon infection by lambda. (1975) (78)
Antigen presentation by dendritic cells focuses T cell responses against immunodominant peptides: studies in the hen egg-white lysozyme (HEL) model. (1998) (78)
Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin-2. (1996) (76)
Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls. (1999) (75)
Cross-Presentation by Dendritic Cells of Tumor Antigen Expressed in Apoptotic Recombinant Canarypox Virus-Infected Dendritic Cells1 (2001) (75)
Altered binding of regulatory factors to HLA class I enhancer sequence in human tumor cell lines lacking class I antigen expression. (1992) (74)
Recurrent T cell receptor rearrangements in the cytotoxic T lymphocyte response in vivo against the p815 murine tumor (1996) (74)
Donor-specific blood transfusion-induced tolerance in adult rats with a dominant TCR-Vbeta rearrangement in heart allografts. (1996) (74)
Screening of cloned recombinant DNA in bacteria by in situ colony hybridization. (1978) (74)
A low polymorphic mouse H-2 class I gene from the Tla complex is expressed in a broad variety of cell types (1987) (73)
A cDNA clone containing the entire coding sequence of a mouse H-2Kd histocompatibility antigen. (1983) (71)
Studies of the messenger RNA of bacteriophage lambda, I. Various species synthesized early after induction of the prophage. (1968) (68)
Structure and expression of the mouse beta 2‐microglobulin gene isolated from somatic and non‐expressing teratocarcinoma cells. (1983) (67)
Evidence for T-cell clonal expansion in a patient with squamous cell carcinoma of the head and neck. (1994) (66)
Expansion of a recurrent V beta 5.3+ T-cell population in newly diagnosed and untreated HLA-DR2 multiple sclerosis patients. (1996) (66)
The expansion and selection of T cell receptor αβ intestinal intraepithelial T cell clones (1996) (65)
DNA-DNA hybridization on filters at low temperature in the presence of formamide or urea. (1971) (65)
Two purified factors bind to the same sequence in the enhancer of mouse MHC class I genes: one of them is a positive regulator induced upon differentiation of teratocarcinoma cells. (1989) (63)
T-cell receptor repertoire and cytokine pattern in granuloma annulare: defining a particular type of cutaneous granulomatous inflammation. (2002) (62)
Immune-mediated destruction of melanocytes in halo nevi is associated with the local expansion of a limited number of T cell clones. (1999) (61)
Molecular cloning of extensive sequences of the in vitro synthesized chicken ovalbumin structural gene. (1977) (60)
MHC restriction, alloreactivity, and thymic education: A common link? (1989) (60)
The complete nucleotide sequence of the mitochondrial DNA of the agnathan Lampetra fluviatilis: bearings on the phylogeny of cyclostomes. (2000) (59)
Synthesis of an ovalbumin-like protein by Escherichia coli K12 harbouring a recombinant plasmid (1978) (59)
Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas. Presence of Valpha24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Valpha repertoire. (2000) (58)
Role of co-stimulation in CD8+ T cell activation. (1998) (58)
Clonal expansions of B lymphocytes in old mice. (1997) (58)
cDNA clone coding for part of a mouse H-2d major histocompatibility antigen. (1981) (55)
The CD14+/lowCD16+ monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14+CD16− subset (2010) (55)
Molecular mechanisms for gene conversion in higher cells (1986) (54)
The peptidic self model: a hypothesis on the molecular nature of the immunological self. (1986) (54)
Adenovirus E1A‐mediated regulation of class I MHC expression. (1986) (54)
Multiple sequences related to classical histocompatibility antigens in the mouse genome (1981) (53)
Quantitative Analysis of the T Cell Repertoire Selected by a Single Peptide–Major Histocompatibility Complex (1998) (52)
High frequency of specific CD8+ T cells in the tumor and blood is associated with efficient local IL-12 gene therapy of cancer. (1999) (52)
Tumor-specific immune response: current in vitro analyses may not reflect the in vivo immune status. (1998) (51)
Fine mapping of epitopes by intradomain Kd/Dd recombinants (1987) (51)
Evidence for Two Subgroups of CD4−CD8− NKT Cells with Distinct TCRαβ Repertoires and Differential Distribution in Lymphoid Tissues1 (2000) (51)
Altered Expression of Tyrosine Kinases of the Src and Syk Families in Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines (1999) (50)
Isolation by molecular cloning of a fragment of the split ovalbumin gene (1978) (50)
Restriction of the T‐cell repertoire in tumor‐infiltrating lymphocytes from nine patients with renal‐cell carcinoma relevance of the CDR3 length analysis for the identification of in situ clonal T‐cell expansions (1996) (46)
Diversity of Human alpha beta T Cell Receptors (2000) (46)
Kinetics of Viral Transcription after Induction of Prophage (1971) (45)
T-cell repertoire analysis in chronic plaque psoriasis suggests an antigen-specific immune response. (1999) (45)
Structure of C-terminal half of two H–2 antigens from cloned mRNA (1981) (45)
Efficient Binding of Reduced Peptide Bond Pseudopeptides to Major Histocompatibility Complex Class I Molecule (*) (1995) (44)
The V beta complementarity determining region 1 of a major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex (1994) (44)
Vα and Vβ Public Repertoires Are Highly Conserved in Terminal Deoxynucleotidyl Transferase-Deficient Mice1 (2005) (43)
Natural Killer T Cells Restricted by the Monomorphic MHC Class 1b CD1d1 Molecules Behave Like Inflammatory Cells1 (2002) (41)
Role of Qa‐1b‐binding receptors in the specificity of developing NK cells (2000) (40)
A single‐chain murine class I major transplantation antigen (1991) (40)
Role of the Complementarity-Determining Region 3 (CDR3) of the TCR-β Chains Associated with the Vα14 Semi-Invariant TCR α-Chain in the Selection of CD4+ NK T Cells1 (2001) (40)
NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. (1992) (40)
Spread of clonal T-cell expansions in rheumatoid arthritis patients. (1996) (38)
Genetic exchanges between partially homologous nucleotide sequences: possible implications for multigene families. (1983) (38)
The expansion of a CD4+ T cell population bearing a distinctive β chain in MRL lpr/lpr mice suggests a role for the fas protein in peripheral T cell selection (1994) (38)
Early Transcription Controls after Induction of Prophage λ (1970) (38)
Molecular cloning of the genome of poliovirus type 1. (1981) (37)
Synthesis of 8-(2-4 dinitrophenyl 2-6 aminohexyl) amino-adenosine 5' triphosphate: biological properties and potential uses. (1982) (35)
Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA. (1983) (35)
Biased amino acid distributions in regions of the T cell receptors and MHC molecules potentially involved in their association. (1991) (34)
DNA-RNA hybridization at low temperature in the presence of urea. (1970) (34)
In vitro induction of specific cytotoxic T lymphocytes using recombinant single-chain MHC class I/peptide complexes. (1998) (33)
Modulation of T-cell functions in KIR2DL3 (CD158b) transgenic mice. (1999) (33)
Contribution of double‐negative thymic precursors to CD8α α + intraepithelial lymphocytes of the gut in mice bearing TCR transgenes (2001) (32)
In vitro induction of naive cytotoxic T lymphocytes with complexes of peptide and recombinant MHC class I molecules coated onto beads: role of TCR/ligand density (1998) (32)
Electron microscopy and restriction enzyme mapping reveal additional intervening sequences in the chicken ovalbumin split gene (1978) (32)
T lymphocyte repertoire in Theiler's virus encephalomyelitis: the nonspecific infiltration of the central nervous system of infected SJL/J mice is associated with a selective local T cell expansion (1995) (31)
Urtica dioica agglutinin, a Vβ8.3‐specific superantigen, prevents the development of the systemic lupus erythematosus‐like pathology of MRL lpr/lpr mice (1996) (31)
Processing of complex heteroduplexes in Escherichia coli and Cos-1 monkey cells. (1984) (30)
T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position (1993) (30)
Lysogenization by bacteriophage lambda. II. Identification of genes involved in the multiplicity dependent processes. (1975) (30)
The peptidic self model: a reassessment of the role of the major histocompatibility complex molecules in the restriction of the T-cell response. (1986) (30)
Analysis of T cell receptor Vβ gene usage in primary mixed lymphocyte reactions : evidence for directive usage by different antigen‐presenting cells and Mls‐like determinants on T cell blasts (1990) (29)
Alternative splicing in the 5′ moiety of the H‐2Kd gene transcript. (1984) (29)
Inhibition of tumor growth by histoincompatible cells expressing interleukin-2. (1992) (29)
Detection of low‐frequency human antigen‐specific CD4+ T cells using MHC class II multimer bead sorting and immunoscope analysis (2004) (28)
The pattern of production of cytokine mRNAs is markedly altered at the onset of multiple sclerosis. (1996) (28)
Vβ T Cell Repertoire of CD8+ Splenocytes Selected on Nonpolymorphic MHC Class I Molecules1 (2000) (28)
Dissociation of the peptide-MHC class I complex limits the binding rate of exogenous peptide. (1993) (27)
PCR-based analysis of the murine immunoglobulin heavy-chain repertoire. (1995) (27)
Evolution of the major histocompatibility complex: a hundred-fold amplification of MHC class I genes in the African pigmy mouse Nannomys setulosus (2004) (26)
Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection. (1991) (26)
Purification and ligand binding of a soluble class I major histocompatibility complex molecule consisting of the first three domains of H-2Kd fused to beta 2-microglobulin expressed in the baculovirus-insect cell system. (1992) (26)
Ontogeny of the heavy chain immunoglobulin repertoire in fetal liver and bone marrow. (1998) (26)
Two factors, IRF1 and KBF1/NF-kappa B, cooperate during induction of MHC class I gene expression by interferon alpha beta or Newcastle disease virus. (1993) (25)
Patterns of integration of exogenous DNA sequences transfected into mammalian cells of primate and rodent origin. (1986) (25)
Phylogenetic distribution in the genus Mus of t-complex-specific DNA and protein markers: inferences on the origin of t-haplotypes. (1988) (25)
A novel approach to the induction of specific cytolytic T cells in vivo. (1990) (25)
The diversity of antigen-specific TCR repertoires reflects the relative complexity of epitopes recognized. (1997) (25)
Development of T cell precursor activity in the murine fetal liver (1998) (25)
A soluble, single‐chain Kd molecule produced by yeast selects a peptide repertoire indistinguishable from that of cell‐surface‐associated Kd (1993) (24)
Cytosolic targeting of hen egg lysozyme gives rise to a short‐lived protein presented by class I but not class II major histocompatibility complex molecules (1991) (24)
Hybridization of filters with competitor DNA in the liquid phase in a standard and a micro-assay. (1974) (24)
Monoclonal antibodies directed against T cell epitopes presented by class I MHC antigens. (1993) (24)
Highly diverse T cell recognition of a single Plasmodium berghei peptide presented by a series of mutant H-2Kd molecules. (1992) (24)
Differential role of conserved and polymorphic residues of the binding groove of MHC class I molecules in the selection of peptides. (1993) (23)
A low molecular weight species of RNA synthesized early after induction of the prophage λ (1971) (23)
Role for MHC class I molecules in selecting and protecting high affinity peptides in the presence of proteases. (1994) (23)
Expression of herpes simplex virus type I thymidine kinase gene in Escherichia coli. (1981) (23)
Description and properties of bacteriophage lambda vectors useful for the cloning of EcoRI DNA fragments. (1978) (22)
Intramolecular recombination between partially homologous sequences in Escherichia coli and Xenopus laevis oocytes. (1987) (22)
Replication inhibition by nucleoside analogues of a recombinant Autographa californica multicapsid nuclear polyhedrosis virus harboring the herpes thymidine kinase gene driven by the IE-1(0) promoter: a new way to select recombinant baculoviruses. (1992) (22)
Monoclonal antibody detection of 2-acetyl-aminofluorene-modified DNA probes for the specific detection of nucleic acids in hybridization procedures. (1985) (22)
Secretion into the bacterial periplasmic space of chicken ovalbumin synthesized in Escherichia coli. (1981) (22)
Comparative structure of two duplicated T1a class I genes (T10c and 37) of the murine H-2d MHC. Implications on the evolution of the T1a region. (1990) (21)
Role of peptide backbone in T cell recognition. (1999) (21)
The TCR-β chain repertoire of gut-derived T lymphocytes (1995) (21)
Altered transcription of genes coding for class I histocompatibility antigens in murine tumor cells (1983) (20)
A new cell surface molecule closely related to mouse class i transplantation antigens (1989) (20)
Extensive structural homology between H-2 K/D/L antigens and non-polymorphic class I Qa, Tla and "37" molecules suggests they may act as peptide carriers. (1989) (20)
Methods for identification of recombinants of phage lambda. (1976) (20)
The Jβ segment of the T cell receptor contributes to the Vβ‐specific T cell expansion caused by staphylococcal enterotoxin B and Urtica dioica superantigens (1996) (20)
Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity. (1997) (20)
Human HLA gene segment isolated by hybridization with mouse H–2 cDNA probes (1981) (20)
Tissue-specific expression of the mouse Q10 H-2 class-I gene during embryogenesis. (1987) (20)
Primary cytotoxic T lymphocyte induction using peptide-stripped autologous cells. (1994) (20)
Many human peripheral VH5-expressing IgM+ B cells display a unique heavy-chain rearrangement. (2008) (20)
Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact. (2000) (19)
Lysogenization by bacteriophage lambda and the regulation of lambda repressor synthesis. (1971) (19)
The ovalbumin gene: an amazing gene in eight pieces (1978) (19)
Valpha and Vbeta public repertoires are highly conserved in terminal deoxynucleotidyl transferase-deficient mice. (2005) (19)
Late transient expression of human hepatitis B virus genes in monkey cells. (1983) (18)
H-2-restricted cytolysis of L cells doubly transformed with a cloned H-2Kb gene and cloned retroviral DNA. (1985) (18)
The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones. (1996) (18)
Facing Two T Cell Epitopes: A Degree of Randomness in the Primary Response Is Lost Upon Secondary Immunization1 (2000) (17)
Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles. (1996) (17)
[Potentiation of the antitumoral effect of electrochemotherapy by immunotherapy with allogeneic cells producing interleukin 2]. (1992) (17)
Insertion of a rabbit beta-globin gene sequence into an E. coli plasmid. (1975) (16)
IL-2 gene delivery within an established murine tumor causes its regression without proliferation of preexisting antitumor-specific CTL. (1997) (16)
Functional expression of a mouse H‐2Kb gene isolated from non‐expressing teratocarcinoma cells. (1984) (16)
Specificity of peptide presentation by a set of hybrid mouse class I MHC molecules (1987) (16)
MHC and MHC‐related proteins as pleiotropic signal molecules (2002) (16)
A monoclonal antibody recognizes a subset of the H-2Dd mouse major class I antigens. (1989) (15)
Isolation of the lysozyme gene of chicken. (1979) (15)
Antitumor vaccination using a major histocompatibility complex (MHC) class I-restricted pseudopeptide with reduced peptide bond. (2000) (15)
A trans-acting mechanism represses the expression of the major transplantation antigens in mouse hybrid thymoma cell lines (1986) (15)
Most residues on the floor of the antigen binding site of the class I MHC molecule H-2Kd influence peptide presentation. (1992) (15)
Dissociation of the peptide/MHC class I complex: pH dependence and effect of endogenous peptides on the activation energy. (1993) (15)
Major histocompatibility complex class I molecules and resistance against intracellular pathogens. (1994) (15)
Introns in the chicken ovalbumin gene prevent ovalbumin synthesis in E. coli K12 (1979) (14)
Generation of hen egg lysozyme‐specific and major histocompatibility complex class I‐restricted cytolytic T lymphocytes: recognition of cytosolic and secreted antigen expressed by transfected cells (1990) (14)
Extensive junctional diversity of Ig heavy chain rearrangements generated in the progeny of single fetal multipotent hematopoietic cells in the absence of selection. (1998) (14)
How important is the direct recognition of polymorphic MHC residues by TCR in the generation of the T-cell repertoire? (1989) (13)
Prognostic value of cytokine and soluble Fcγ receptor assays in oncology (1995) (13)
Monoclonal antibodies to DNA modified by the carcinogen N-acetoxy-N-2 acetyl aminofluorene. (1984) (13)
A clonal view of αβ T cell responses (1999) (13)
Ly‐49‐independent inhibition of natural killer cell‐mediated cytotoxicity by a soluble major histocompatibility complex class I molecule (1994) (13)
A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis. (2002) (12)
The natural defense system and the normative self model (2016) (12)
Identification of T cell peptides from C gamma 2ab involved in IgG2ab T cell-induced allotypic suppression. Relationship with the MHC haplotype of the suppressor T cell-donor Igha mice. (1993) (12)
Alloimmunization Against Well Defined Polymorphic Major Histocompatibility or Class I MHC Transfected L Cells Antigens Can Prevent Poly IC Induced Fetal Death in Mice (1995) (12)
Clonality of tumor-infiltrating lymphocytes in human urinary bladder carcinoma. (1997) (12)
An H-2K gene of the tw32mutant at the T/t complex is a close parent of an H-2Kqgene (2004) (12)
T Cell Repertoire Diversity Is Required for Relapses in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis1 (2007) (12)
Synthesis of a chicken ovalbumin-like protein in the yeast Saccharomyces cerevisiae. (1980) (12)
Role of the CDR1 region of the TCR beta chain in the binding to purified MHC-peptide complex. (1994) (11)
Enrichment of antigen-specific T lymphocytes by panning on immobilized MHC-peptide complexes. (1997) (11)
The peripheral CD8 T cell repertoire is largely independent of the presence of intestinal flora. (2000) (11)
An active T-cell-independent mechanism enhances MHC class I transcription and expression on a mouse T-cell lymphoma in vivo. (1987) (11)
The interaction of antigenic peptides with the H-2Kd MHC class I molecule. (1993) (11)
TCR-beta repertoire development in the mouse embryo. (1997) (11)
Strong alloantigenicity of the alpha-helices residues of the MHC class I molecule. (1998) (11)
T cells recognize antigen alone and not MHC molecules. (1987) (11)
DNA organisation in the chicken lysozyme gene region. (1981) (11)
The TCR-beta chain repertoire of gut-derived T lymphocytes. (1995) (10)
Polymorphism in mouse and human class I H-2 and HLA genes is not the result of random independent point mutations (2004) (10)
nonclassical human monocyte subsets Gene expression profiling reveals the defining features of the classical (2011) (10)
Use of synthetic peptide libraries for the H-2Kd binding motif identification. (1995) (10)
Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCR alpha beta repertoires and differential distribution in lymphoid tissues. (2000) (9)
Wegener's autoantigen and leukemia. (1991) (9)
Evolution within the multigene family coding for the class I histocompatibility antigens: the case of the mouse t-haplotypes. (1985) (9)
Intradomain H‐2 Kd/Dd recombinants define the same regions as crucial for recognition by alloreactive or major histocompatibility complex‐restricted cytolytic T cells (1989) (9)
Mouse genes coding for the major class I transplantation antigens: a mosaic structure might be related to the antigenic polymorphism. (1982) (9)
Contribution of double-negative thymic precursors to CD8alpha alpha (+) intraepithelial lymphocytes of the gut in mice bearing TCR transgenes. (2001) (9)
Correction of complex heteroduplexes made of mouse H-2 gene sequences in Escherichia coli K-12. (1984) (9)
Mutational analysis and molecular modeling of the binding of Staphylococcus aureus enterotoxin C2 to a murine T cell receptor Vβ10 chain (2002) (9)
MOLECULAR DEFINITION OF RETROVIRUS‐INDUCED ANTIGENS RECOGNIZED BY TUMOUR‐SPECIFIC H‐2‐RESTRICTED CYTOLYTIC T LYMPHOCYTES (1986) (8)
Binding of alanine‐substituted peptides to the MHC class I protein, Kd (1993) (8)
The J beta segment of the T cell receptor contributes to the V beta-specific T cell expansion caused by staphylococcal enterotoxin B and Urtica dioica superantigens. (1996) (8)
Induction of CD8 molecules on thymic γ/δ T cells in vitro is dependent upon α/β T cells (1991) (8)
Does a quorum sensing mechanism direct the behavior of immune cells? (2013) (8)
Delayed and Separate Costimulation In Vitro Supports the Evidence of a Transient “Excited” State of CD8+ T Cells During Activation (2000) (8)
The structure and function of MHC molecules. Possible implications for the control of tumor growth by MHC-restricted T cells. (1991) (8)
Picosecond fluorescence spectroscopy of a single-chain class I major histocompatibility complex encoded protein in its peptide loaded and unloaded states. (1994) (8)
Escape synthesis of β-galactosidase under the control of bacteriophage lambda (1976) (8)
Duplication of the CD8 beta-chain gene as a marker of the man-gorilla-chimpanzee clade. (1993) (7)
Rare sequence motifs are common constituents of hypervariable antibody regions. (1987) (7)
Conventional and non-conventional recognition of non-peptide antigens by T lymphocytes. (1999) (7)
European Commission COST/STD Initiative. Report of the expert panel VII. Vaccine delivery systems. (1996) (7)
Comparative expression of the hepatitis B surface antigen gene in biochemically transformed human, simian and murine cells. (1985) (7)
The ovalbumin split gene: molecular cloning of Eco RI fragments "c" and "d". (1978) (7)
Regulatory elements involved in the liver-specific expression of the mouse MHC class I Q10 gene: characterization of a new TATA-binding factor. (1990) (7)
Binding of low concentration of peptide to H-2Kd produced in insect cells requires mouse beta 2-microglobulin co-expression. (1992) (6)
Transcription of a mammalian sequence under phage λ control (1977) (6)
The in vivo antibody response to hen egg white lysozyme in H-2b-compatible responder and non-responder mice: is it regulated by its N-terminal peptide at the level of antigen-presenting cells? (1991) (6)
Revised nomenclature of mouseH-2 genes (2005) (6)
Is antigen processing guided by major histocompatibility complex molecules? (1994) (6)
V beta T cell repertoire of CD8+ splenocytes selected on nonpolymorphic MHC class I molecules. (2000) (6)
Follow-up of the T-cell clonality in Sezary patients treated by extracorporeal photopheresis using a new assay: the immunoscope technique. (2003) (6)
Role of the complementarity-determining region 3 (CDR3) of the TCR-beta chains associated with the V alpha 14 semi-invariant TCR alpha-chain in the selection of CD4+ NK T Cells. (2001) (6)
Lysogenization by bacteriophage lambda IV inhibition of phage DNA synthesis by the products of genes cII and cIII. (1977) (6)
Maternal immunoglobulins have no effect on the rate of maturation of the B cell compartment of the offspring (1997) (5)
Field Actions Science Reports (2009) (5)
Selfish cellular networks and the evolution of complex organisms. (2012) (5)
Expression and characterization of recombinant mouse beta 2-microglobulin type a in insect cells infected with recombinant baculoviruses. (1991) (5)
Cloning of the herpes simplex virus type 1 thymidine kinase gene in E. coli K 12: a selective marker for gene transfer into animal cells. (1980) (5)
A clonal view of alphabeta T cell responses. (1999) (5)
Une méthode de dosage quantitatif d'acides nucléiques par amplification enzymatique (méthode PCR) à saturation (1992) (5)
Their Molecular Imprint on the Human Epitope : Application to Direct Detection of Response Against a Dominant EBV-Derived with Public TCR Features to the Chronic Frequent Contribution of T Cell (2000) (5)
Immunological issues in vaccine trials: T-cell responses. (1998) (4)
On the molecular nature of "restrictive" antigenic elements present on major histocompatibility complex (MHC) proteins. (1989) (4)
Safety standards: An urgent need for Evidence-Based Regulation (2008) (4)
[Quantitative determination method of nucleic acids by enzymatic amplification (PCR method) to saturation]. (1992) (4)
Selectable markers for the transfer of genes into mammalian cells. (1982) (4)
IL-2 gene transduction in malignant cells: applications in cancer containment. (1992) (4)
FURTHER SEROLOGICAL AND RFLP ANALYSIS OF THE MRL‐+/+ AND MRL‐lpr/lpr MICE (1988) (4)
Modulation of T-Cell Functions in KIR 2 DL 3 ( CD 158 b ) Transgenic Mice (1999) (4)
Altruity: Key to the Fight Against Poverty (2012) (3)
What is the best way to define the antimelanocyte T cell repertoire? (1999) (3)
TCR V beta repertoire in LEW.1W heart allografts acutely rejected by LEW.1A recipients is restricted and comprises a public response. (1997) (3)
Immunoscope analysis of T-lymphocytes infiltrating melanocytic tumors. (2001) (3)
Two factors, IRF1 and KBF1/NF-κB, cooperate during induction of MHC class I gene expression by interferon αβ or Newcastle disease virus (1993) (3)
Use of isolators in recombinant DNA research. (1977) (3)
A sequence from Drosophila DNA cross-hybridizing with a mouse class I H-2 gene: absence of relevant nucleic acid or amino acid sequence homology. (1985) (3)
Peptide binding to MHC class I proteins measured with a novel fluorescent technique. (1992) (3)
Purification and ligand binding of a soluble class I MHC molecule consisting of the first three domains of H-2Kd fused to b2-microglobulin expressed in the baculovirus/insect cell system (1992) (3)
Prognostic value of cytokine and soluble Fc gamma receptor assays in oncology. (1995) (3)
Construction of a dominant selective marker useful for gene transfer studies in animal cells. (1981) (3)
Preface: Human Immunology at SIgN (2012) (2)
Quality control of immune self non-self discrimination (2003) (2)
Major contribution of the Vb chain to the antigen specificity of a TCR (1994) (2)
The role of the adenovirus E1a region in transformation and oncogenesis (1986) (2)
Attempts to purify a membrane attached chromoid of bacteriophage lambda. (1976) (2)
Chain in the Selection of CD 4 α TCR 14 Semi-Invariant α Associated with the V Chains β Region 3 ( CDR 3 ) of the TCR-Role of the Complementarity-Determining (2001) (2)
Gene action and its control in micro-organisms (1970) (2)
Systematic and systemic immunology: on the future of research and its applications (2012) (2)
e- Blood Gene expression proﬁling reveals the deﬁning features of the classical, intermediate, and nonclassical human monocyte subsets (2011) (2)
Les Sciences qui s'ignorent (2011) (2)
Immune prevention and therapy (1999) (2)
Cord blood αβ T-cell repertoire has characteristics of a naive but completely formed repertoire (1997) (2)
Stable HBV surface antigen expression by Vero cell clones after transfection. (1985) (1)
Quantitative PCR with colorimetric detection. (1996) (1)
The intratumoral application of poly-G-oligodeoxynucleotides does not augment the naturally induced antitumoral CD8-T-cell response in P815 mastocytomas. (2003) (1)
Functional analysis of the mouse H-2Kb gene promoter in embryonal carcinoma cells (2004) (1)
Unification for European Immunology? (2001) (1)
A low molecular weight species of RNA synthesized early after induction of the prophage lambda. (1971) (1)
[Inhibition of the tumoral growth induced by the injection of histo-incompatible cells producing interleukin-2]. (1992) (1)
Insertion of a rabbit beta-globin gene sequence into an E. coli plasmid. 1975. (1992) (1)
A sensitive assay for egg white lysozyme and phage endolysins. (1974) (1)
Major contribution of the beta chain to the antigen specificity of a T cell receptor. (1994) (1)
Oligoclonal T cell response in psoriatic cutaneous lesions (1994) (1)
Alternative splicing in the mouse H-2kdgene is not necessary for the classical Kd antigen function (2004) (1)
Vb T Cell Repertoire of CD8 Splenocytes Selected on Nonpolymorphic MHC Class I Molecules (2000) (1)
Replication of certain lambda mutants is cold-sensitive. (1978) (1)
The organization and expression of the eukaryotic genome, E.M. Bradbury, K. Javaherian. Academic Press, New-York and London (1977), £ 13,50, $ 26,50. (1978) (0)
Halo-nevus phenomenon is associated with few T-cell expansions characterized by a unique β chain (1998) (0)
Fragments of DNA marks has at least one of their ends by ribonucleotide modified recognizable by affine molecules and method to realize an analysis of such fragments of DNA (1981) (0)
Systematic and systemic immunology: on the future of research and its applications (2012) (0)
Report on the International Symposium on Vaccinology, November 18-20, Paris, France, organized by the Académie des Sciences and the Marcel Mérieux Foundation. (1999) (0)
Foreword by Philippe Kourilsky (2013) (0)
Major histocompatibility complex class I molecules and resistance to infection by intracellular pathogens (1994) (0)
Method for determination of the quantity of a DNA fragment of interest by an enzymatic amplification method. (1991) (0)
Samples Symposium Ceremony (2003) (0)
[Messenger RNA synthesized after lambda prophage induction]. (1969) (0)
The T cell repertoire in response to foreign and self-antigens. (1992) (0)
Efficient Local IL-12 Gene Therapy of Cancer the Tumor and Blood Is Associated with T Cells in + High Frequency of Specific CD8 (0)
Introduction: Brief Overview on the Major Histocompatibility Complex (2020) (0)
The importance of phage research in the development of contemporary biology. (1971) (0)
Theovalbumin split gene:molecular cloning ofEcoRIfragments "c"and"d". (1978) (0)
Bacterial, phage and molecular genetics, M. Winckler, W. Ruger, W. Wackernagel, in: An Experimental course. Springer (1975) (1977) (0)
Lambda control systems. In: strategy of the viral genome. (1971) (0)
[4 years ago, Jacques Monod]. (1980) (0)
Genetic Analysis at the Molecular Level (1998) (0)
Method and reagent kit for the detection and characterization of nucleic acids and their sequences (1979) (0)
Diversity of exon 2 of major histocompatibility complex class I genes in wild mice (2004) (0)
[The gene in 1979]. (1980) (0)
Lambda Control Systems (2008) (0)
Repertoire in Fetal Liver and Bone Marrow Ontogeny of the Heavy Chain Immunoglobulin (1998) (0)
The Game of Survival, Chance and Complexity (2018) (0)
FACTS Reports: Second birthday (2010) (0)
Clonality of Tumor-Infiltrating Lymphocytes in Human Urinary Bladder Carcinoma (1998) (0)
Cellsand Inhibit the Function of Infiltrating T Human Metastatic Melanoma Lymph Nodes Regulatory T Cells Are Overrepresented in high CD25+ Foxp3 Expressing CD4 (2004) (0)
Transcription of a mammalian sequence under phage lambda control. (1977) (0)
Rational approach to risks (1977) (0)
Squamous Cell Carcinoma of the Head and Neck Evidence for T-Cell Clonal Expansion in a Patient with Updated (2006) (0)
Immunity to virus infection (excluding retroviruses) (PP-025) (2010) (0)
Composition for the treatment of tumors and the immunization of organisms against tumors. (1993) (0)
Co-expression of T-cell receptor beta and delta mRNA detected at high frequency in hybridomas derived from adult thymus. (1992) (0)
a8-chain gene as a marker of the man-gorilla-chimpanzee clade (2005) (0)
Induction of CD8 molecules on thymic gamma/delta T cells in vitro is dependent upon alpha/beta T cells. (1991) (0)
[Expression of foreign genes in Escherichia coli: problems and perspectives (proceedings)]. (1978) (0)
[Production of 2 messenger RNA's with high sedimentation constants at the beginning of the vegetative cycle of the gamma prophage]. (1967) (0)
Alternative Splicing in the H-2 Multigene Family (1985) (0)
Upon Secondary Immunization Randomness in the Primary Response Is Lost Facing Two T Cell Epitopes: A Degree of (0)
Molecular analysis of the cytolytic T-lymphocyte response elicited by retrovirus-induced tumours in mice. (1986) (0)
T cells and vaccination (1998) (0)
Use of an h-2 cdna probe to map h-2tw32 genes. Abstr. (1983) (0)
The new initiative of field actions science: FACTS (2009) (0)
Peptides having protective properties of a pathogenic virus hiv type in sensitive cells (1988) (0)
Patent applications and recombinant DNA (1977) (0)
Probe containing a nucleic acid modifies and recognizable by specific antibodies and use of this probe to detect and characterize a homologous DNA sequence (1981) (0)
Genetic localization of two polycistronic messenger RNAs from bacteriophage lambda as deduced from their base compositions and annealing properties (2004) (0)
Strong Alloantigenicity of the α-Helices Residues of the MHC Class I Molecule (1998) (0)
[A study, using zone centrifugation, of the initial functions and viral-specified products of lambda]. (1967) (0)
Fighting Poverty , between market and gift Altruity : Key to the Fight Against Poverty (2016) (0)
Thoughtful cruises in oceans of peptides and T cells. (1995) (0)
CD1d is not necessary for NKT-dependant granuloma induction by bacterial glycolipids (2001) (0)
A pharmaceutical composition comprising NKT cells that are activated by the PIM, and their use in therapy (2000) (0)
Pattern of Gene Transcription During the Induction of Bacteriophage Lambda Development: A Possible Model for the Control of Gene Expression in a Differentiating System (2008) (0)
Antibodies Antibody Reagents specificity Monoclonal H-2 GENE REGULATION IN CELL HYBRIDS (2003) (0)
Complex Expression of the Mouse H-2 Class I Genes (1987) (0)
Process for detecting and characterizing a nucleic acid or a sequence thereof, and enzymatic reagent for the implementation of such process (1978) (0)
Autoimmune Encephalomyelitis Glycoprotein-Induced Experimental Relapses in Myelin Oligodendrocyte T Cell Repertoire Diversity Is Required for (2007) (0)
Escape synthesis of beta-galactosidase under the control of bacteriophage lambda. (1976) (0)
Oligoclonal Repertoire of the CD8c~c~ and the CD8cx/3 TCR-cx/13 Murine Intestinal Intraepithelial T Lymphocytes: Evidence for the Random Emergence of T Cells By ArmeUe Regnault,* Ana Cumano,* Pierre VassaUi,S (1994) (0)
Analysis of Specificities Recognized by Monoclonal Antibodies and Cytotoxic T-Lymphocytes Using Chimeric H-2 Molecules (1988) (0)
1 ( HEL ) Model Peptides : Studies in the Hen Egg-White Lysozyme T Cell Responses Against Immunodominant Antigen Presentation by Dendritic Cells Focuses (1998) (0)
[Methods of studying T-lymphocyte repertoires]. (2002) (0)
Restriction map of poliovirus type 2 cDNA. (1981) (0)
Interleukin 6 Gene Expression in Invasive Carcinoma1 (1994) (0)
[An immunological Noah's Ark]. (2009) (0)
Acid 5'-triphosphate adenosine modifies and method of assay of biological substances capable of binding the degradation products of adenosine 5'-triphosphate acid (1981) (0)
Transferase-Deficient Mice Conserved in Terminal Deoxynucleotidyl Public Repertoires Are Highly β and V α V (2013) (0)
[Isolation and characterization of monoclonal antibody directed against antigenic peptide presented by class I histocompatibility molecule]. (1992) (0)
Detection of multipotent hematopoietic cells in pre-liver embryos (1996) (0)
Are First‐World Ethics Applicable to the Third World? (2008) (0)
Method to generate a population of cells presenting on their surface a high density of a specific exogenous pepride AZX combines molecules of cmh; cell population (1994) (0)
P583 - Vβ18-Dβ1-Jβ2.7 T-cell clonality in graft infiltrating cells in donor specific transfusion-induced allograft tolerance (1996) (0)
Preface: Human Immunology at SIgN (2012) (0)
Complex Regulation of MHC Class I Expression: Constitutive and Modulated Patterns of Expression (1989) (0)
Induction of specific CTL by use of cells presenting a high density of MHC peptide complex (2007) (0)
Nomenclature Revised nomenclature of mouse B-2 genes (1993) (0)
Using a cellular composition for the treatment of human or animal organisms (1992) (0)
Model of the MHC class I H-2Kd molecule-peptide complex (1994) (0)
[Genetically modified cells as vectors of local secretion of cytokines. Perspectives in antitumoral immunotherapy]. (1995) (0)
41. Field Actions Science (FACTS) : une nouvelle initiative destinée aux acteurs de terrain (2011) (0)
The Dominant Selective Marker APH 3′ and the Study of the Expression of the Cotransfected Gene (1983) (0)
[Biochemical transformation of animal cells in culture]. (1979) (0)

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