Peter Nigel Leigh
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Biology
Peter Nigel Leigh's Degrees
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Peter Nigel Leigh's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis (2008) (2389)
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6 (2009) (2360)
- Fronto-striatal cognitive deficits at different stages of Parkinson's disease. (1992) (884)
- Motor neuron disease. (1994) (515)
- Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis (2009) (508)
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis (2016) (424)
- Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS) (2000) (406)
- Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. (2007) (390)
- Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis. (2001) (372)
- Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis (2009) (358)
- Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity. (1991) (346)
- Amyotrophic lateral sclerosis (2009) (342)
- Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS Study (2008) (305)
- Ubiquitin deposits in anterior horn cells in motor neurone disease (1988) (293)
- Reorganization of cortical blood flow and transcranial magnetic stimulation maps in human subjects after upper limb amputation. (1994) (285)
- Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study. (1996) (276)
- Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration (2008) (274)
- Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction. (1994) (272)
- Cortical function in amyotrophic lateral sclerosis. A positron emission tomography study. (1993) (269)
- Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study (2014) (266)
- The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study. (1993) (266)
- A proposed staging system for amyotrophic lateral sclerosis (2012) (263)
- Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. (1997) (253)
- Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study (2010) (247)
- Functional magnetic resonance imaging of verbal fluency and confrontation naming using compressed image acquisition to permit overt responses (2003) (243)
- Visuospatial memory deficits at different stages of Parkinson's disease (1993) (243)
- Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia (1992) (243)
- A prospective study of quality of life in ALS patients treated with noninvasive ventilation (2001) (238)
- Biomarkers in amyotrophic lateral sclerosis (2009) (231)
- Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport. (2002) (211)
- Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments (2003) (200)
- Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis (2009) (197)
- Good practice in the management of amyotrophic lateral sclerosis: Clinical guidelines. An evidence‐based review with good practice points. EALSC Working Group (2007) (197)
- NEK1 variants confer susceptibility to amyotrophic lateral sclerosis (2016) (195)
- Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons (2000) (182)
- Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil. (2000) (176)
- The effect of non-invasive positive pressure ventilation (NIPPV) on cognitive function in amyotrophic lateral sclerosis (ALS): a prospective study (2001) (161)
- Clinical care of patients with amyotrophic lateral sclerosis (2007) (158)
- The sex ratio in amyotrophic lateral sclerosis: A population based study (2010) (152)
- Is language impairment more common than executive dysfunction in amyotrophic lateral sclerosis? (2012) (148)
- Cu/Zn superoxide dismutase gene mutations in amyotrophic lateral sclerosis: correlation between genotype and clinical features. (1996) (147)
- Amyotrophic lateral sclerosis in an urban setting: a population based study of inner city London. (2006) (147)
- Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study (2018) (145)
- Flail arm syndrome: a distinctive variant of amyotrophic lateral sclerosis (1998) (141)
- Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: Analysis of 155 cases and identification of novel insertion mutation (1997) (140)
- The effect of noninvasive ventilation on ALS patients and their caregivers (2006) (140)
- Cognitive change in ALS (2005) (136)
- Predictors of psychological distress in carers of people with amyotrophic lateral sclerosis: a longitudinal study (2006) (130)
- Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy (2009) (122)
- The psychological impact of motor neurone disease (1994) (119)
- Respiratory aspects of neurological disease (1999) (118)
- Nutritional management in MND/ALS patients: an evidence based review (2004) (117)
- A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group. (1998) (116)
- The anatomy of cognitive impairment in amyotrophic lateral sclerosis: More than frontal lobe dysfunction (2012) (110)
- Cough augmentation in amyotrophic lateral sclerosis (2003) (102)
- Amyotrophic lateral sclerosis with sensory neuropathy: part of a multisystem disorder? (2006) (101)
- Living with motor neurone disease: lives, experiences of services and suggestions for change. (2005) (101)
- Predictors of survival in progressive supranuclear palsy and multiple system atrophy: a systematic review and meta-analysis (2017) (99)
- Cytoskeletal abnormalities in motor neuron disease. An immunocytochemical study. (1989) (99)
- Recent advances in amyotrophic lateral sclerosis (2000) (98)
- Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3. (2000) (97)
- Estimating clinical stage of amyotrophic lateral sclerosis from the ALS Functional Rating Scale (2014) (97)
- Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q. (2003) (95)
- ALS2/Alsin Regulates Rac-PAK Signaling and Neurite Outgrowth* (2005) (93)
- p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction. (2001) (90)
- Symptoms and Quality of Life in Late Stage Parkinson Syndromes: A Longitudinal Community Study of Predictive Factors (2012) (89)
- Cortical function in progressive lower motor neuron disorders and amyotrophic lateral sclerosis (1994) (89)
- Symptom prevalence, severity and palliative care needs assessment using the Palliative Outcome Scale: A cross-sectional study of patients with Parkinson’s disease and related neurological conditions (2013) (86)
- Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: A double- blind, randomized, multicentre, placebo-controlled trial (2009) (85)
- Safety, Pharmacokinetic, and Functional Effects of the Nogo-A Monoclonal Antibody in Amyotrophic Lateral Sclerosis: A Randomized, First-In-Human Clinical Trial (2014) (85)
- Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy. (1998) (84)
- Relationships between Lewy bodies and pale bodies in Parkinson's disease (2004) (82)
- Altered cortical activation during a motor task in ALS (2000) (82)
- Amyotrophic lateral sclerosis in an urban setting (2006) (82)
- Behavioural and emotional symptoms of apathy are associated with distinct patterns of brain atrophy in neurodegenerative disorders (2013) (81)
- Disease Severity and Progression in Progressive Supranuclear Palsy and Multiple System Atrophy: Validation of the NNIPPS – PARKINSON PLUS SCALE (2011) (80)
- Use of clinical staging in amyotrophic lateral sclerosis for phase 3 clinical trials (2014) (78)
- Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome (2019) (77)
- Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease (1995) (75)
- Neurofibrillary tangles in dementia pugilistica are ubiquitinated. (1991) (74)
- Excitotoxicity in ALS (1996) (72)
- Amyotrophic lateral sclerosis: glutamate dehydrogenase and transmitter amino acids in the spinal cord. (1991) (71)
- A patient with reflex myoclonus and muscle rigidity: "jerking stiff-man syndrome". (1980) (71)
- The emotional lability questionnaire: a new measure of emotional lability in amyotrophic lateral sclerosis (1999) (70)
- Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials (2017) (69)
- Cytoskeletal pathology in motor neuron diseases. (1991) (69)
- Diffusion Tensor Imaging of Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy: A Tract-Based Spatial Statistics Study (2014) (68)
- Use of apomorphine in parkinsonian patients with neuropsychiatric complications to oral treatment. (1997) (66)
- Longitudinal predictors of psychological distress and self-esteem in people with ALS (2006) (65)
- Latent Cluster Analysis of ALS Phenotypes Identifies Prognostically Differing Groups (2009) (65)
- Presynaptic and postsynaptic striatal dopaminergic function in neuroacanthocytosis: A positron emission tomographic study (1991) (63)
- A clinical tool for predicting survival in ALS (2016) (63)
- Identification of a Novel, Membrane-Associated Neuronal Kinase, Cyclin-Dependent Kinase 5/p35-Regulated Kinase (2003) (63)
- A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis (1995) (62)
- Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: Homozygous naip deletion in a sporadic case (1996) (62)
- Ethical and clinical issues in the use of home non-invasive mechanical ventilation for the palliation of breathlessness in motor neurone disease (1999) (62)
- The validation of El Escorial criteria for the diagnosis of amyotrophic lateral sclerosis: A clinicopathological study (1995) (61)
- Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial (2004) (61)
- Involvement of the amygdala, dentate and hippocampus in motor neuron disease (1995) (60)
- Low index-to-ring finger length ratio in sporadic ALS supports prenatally defined motor neuronal vulnerability (2011) (60)
- Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis. (2016) (58)
- Electrical injury and amyotrophic lateral sclerosis: a systematic review of the literature (2006) (57)
- Characterizing axonal myelination within the healthy population: a tract-by-tract mapping of effects of age and gender on the fiber g-ratio (2017) (56)
- C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: A genome‐wide meta‐analysis (2014) (56)
- Neurite orientation and dispersion density imaging (NODDI) detects cortical and corticospinal tract degeneration in ALS (2018) (55)
- Distribution of NADPH-diaphorase positive cells in the rat brain. (1990) (54)
- Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases (2018) (52)
- An Overview of MicroRNAs as Biomarkers of ALS (2019) (52)
- Mapping of Gene Expression Reveals CYP27A1 as a Susceptibility Gene for Sporadic ALS (2012) (52)
- The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci (2009) (52)
- Comparison of the King’s and MiToS staging systems for ALS (2017) (51)
- Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS (1999) (51)
- Cortical Thickness, Surface Area and Volume Measures in Parkinson's Disease, Multiple System Atrophy and Progressive Supranuclear Palsy (2014) (49)
- p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis. (2004) (49)
- Defining survival as an outcome measure in amyotrophic lateral sclerosis. (2009) (48)
- Entristar skin-level gastrostomy tube: primary placement with radiologic guidance in patients with amyotrophic lateral sclerosis. (2004) (48)
- Cortical involvement in four cases of primary lateral sclerosis using [11C]-flumazenil PET (2007) (48)
- A common haplotype within the PON1 promoter region is associated with sporadic ALS (2008) (47)
- Diffusion tensor imaging in sporadic and familial (D90A SOD1) forms of amyotrophic lateral sclerosis. (2009) (46)
- Clinical trials in ALS: an overview. (2001) (45)
- New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies (2004) (45)
- Motor neurone disease: A review of its emotional and cognitive consequences for patients and its impact on carers (1999) (44)
- A RAPID SCREENING BATTERY TO IDENTIFY FRONTAL DYSFUNCTION IN PATIENTS WITH ALS (2007) (44)
- Trouble on the pitch: are professional football players at increased risk of developing amyotrophic lateral sclerosis? (2005) (43)
- Automated, High Accuracy Classification of Parkinsonian Disorders: A Pattern Recognition Approach (2013) (42)
- Patients' health-related quality-of-life and health state values for motor neurone disease/amyotrophic lateral sclerosis (2003) (41)
- Androgen‐induced up‐regulation of tubulin isoforms in neuroblastoma cells (2001) (41)
- Geographical Clustering of Amyotrophic Lateral Sclerosis in South-East England: A Population Study (2008) (40)
- Altered patterns of cortical activation in ALS patients during attention and cognitive response inhibition tasks (2011) (40)
- Psychological as well as illness factors influence acceptance of non-invasive ventilation (NIV) and gastrostomy in amyotrophic lateral sclerosis (ALS): A prospective population study (2014) (39)
- Cortical activation during motor imagery is reduced in Amyotrophic Lateral Sclerosis (2007) (39)
- Enterovirus infection of the central nervous system of humans: lack of association with chronic neurological disease. (1996) (38)
- Indicators and Prevalence of Malnutrition in Motor Neurone Disease (1998) (37)
- Erratum: Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease (The Lancet, vol. 339/8806 (1375-1377)) (1992) (36)
- Exploring the temporal nature of hemodynamic responses of cortical motor areas using functional MRI (1998) (36)
- Syntactic processing as a marker for cognitive impairment in amyotrophic lateral sclerosis (2015) (36)
- The benefit of evolving multidisciplinary care in ALS: a diagnostic cohort survival comparison (2017) (35)
- Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study (2014) (35)
- Spinal cord trauma in man: studies of phosphorylated neurofilament and ubiquitin expression. (1990) (34)
- Cognitive deficits in non-demented amyotrophic lateral sclerosis patients: a neuropsychological investigation (1995) (33)
- Genetic and epigenetic studies of amyotrophic lateral sclerosis (2013) (29)
- Neurotrophin-3-like immunoreactivity and Trk C expression in human spinal motoneurones in amyotrophic lateral sclerosis (1997) (29)
- Symptom Prevalence among People Affected by Advanced and Progressive Neurological Conditions—a Systematic Review (2007) (29)
- Neuroprotective effect of free radical scavengers on β-N-oxalylamino-l-alanine (BOAA)-induced neuronal damage in rat hippocampus (1994) (28)
- A new MRI rating scale for progressive supranuclear palsy and multiple system atrophy: validity and reliability (2011) (28)
- Decision Making About Gastrostomy and Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (2016) (28)
- Late-onset Tay–Sachs disease (2017) (28)
- Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis (2014) (28)
- β-amyloid precursor protein fragments and lysosomal dense bodies are found in rat brain neurons after ventricular infusion of leupeptin (1994) (27)
- Neuronal damage induced by ß-N-oxalylamino-l-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (1993) (27)
- Marital relationships in amyotrophic lateral sclerosis (2010) (27)
- Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat (2013) (26)
- Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells (2002) (26)
- Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis (2016) (26)
- C9orf72 and UNC13A are shared risk loci for ALS and FTD: A genome-wide meta-analysis (2014) (26)
- Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial (2020) (25)
- Mushroom-cage gastrostomy tube placement in patients with amyotrophic lateral sclerosis: a 5-year experience in 104 patients in a single institution (2009) (25)
- Imaging: MRS/MRI/PET/SPECT: Summary (2002) (24)
- Variants in the ALS2 gene are not associated with sporadic amyotrophic lateral sclerosis (2003) (24)
- Identification of a potential non-coding RNA biomarker signature for amyotrophic lateral sclerosis (2020) (23)
- Imaging the brain during sniffing: a pilot fMRI study. (2009) (23)
- Routes of excretion of neuronal lysosomal dense bodies after ventricular infusion of leupeptin in the rat: a study using ubiquitin and PGP 9.5 immunocytochemistry (1993) (22)
- The moving ear syndrome: a focal dyskinesia. (1996) (22)
- Emerging Magnetic Resonance Imaging Techniques and Analysis Methods in Amyotrophic Lateral Sclerosis (2018) (22)
- Palliative care in motor neurone disease. (1995) (21)
- Eating-derived pleasure in amyotrophic lateral sclerosis as a predictor of non-oral feeding (2012) (21)
- Occasional essay: Upper motor neuron syndrome in amyotrophic lateral sclerosis (2020) (20)
- Genome‐wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy (2019) (19)
- Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31] (2011) (19)
- Oral levosimendan in amyotrophic lateral sclerosis: a phase II multicentre, randomised, double-blind, placebo-controlled trial (2019) (19)
- Chapter 13 Amyotrophic lateral sclerosis. (2007) (19)
- Amino acids for amyotrophic lateral sclerosis / motor neuron disease. (2008) (19)
- Critical design considerations for time-to-event endpoints in amyotrophic lateral sclerosis clinical trials (2019) (19)
- Absence of cognitive, behavioral, or emotional dysfunction in progressive muscular atrophy (2006) (18)
- Evidence of an environmental effect on survival in ALS (2014) (18)
- Minocycline for patients with ALS (2008) (17)
- Positron emission tomography (PET) – its potential to provide surrogate markers in ALS (2000) (17)
- Debrisoquine hydroxylase gene polymorphism in Parkinson's disease and amyotrophic lateral sclerosis. (1995) (16)
- The Economic Costs of Progressive Supranuclear Palsy and Multiple System Atrophy in France, Germany and the United Kingdom (2011) (15)
- Gigaxonin is associated with the Golgi and dimerises via its BTB domain (2004) (15)
- Magnetic resonance spectroscopic study of parkinsonism related to boxing. (1995) (15)
- Predicting the future of ALS: the impact of demographic change and potential new treatments on the prevalence of ALS in the United Kingdom, 2020–2116 (2019) (15)
- Alzheimer’s disease, amyotrophic lateral sclerosis, and transgenic mice (1998) (14)
- Homozygosity analysis in amyotrophic lateral sclerosis (2013) (14)
- Morphological differences of intraneuronal ubiquitin‐positive inclusions in the dentate gyrus and parahippocampal gyrus of motor neuron disease with dementia (2004) (14)
- The effect of polyglutamine expansion in the human androgen receptor on its ability to suppress β-catenin-Tcf/Lef dependent transcription (2004) (14)
- Motor neuron disease: Focusing the mind on ALS: updated practice parameters (2010) (13)
- Superoxide dismutase activity in lymphoblastoid cells from motor neurone disease/amyotrophic lateral sclerosis (MND/ALS) patients (1995) (11)
- The Molecular Pathology of Motor Neuron Disease (1995) (11)
- Society for Neuroscience Abstracts (2001) (11)
- Epilepsy as the presenting feature of neuroacanthocytosis in siblings (1992) (10)
- Positron emission tomography (PET)--its potential to provide surrogate markers in ALS. (2000) (10)
- Immunocytochemical studies of neurotrophins in cerebral motor cortex in Amyotrophic Lateral Sclerosis (1997) (10)
- Legionella brain stem encephalopathy and peripheral neuropathy without preceding pneumonia. (1986) (10)
- Evolution of white matter damage in amyotrophic lateral sclerosis (2020) (10)
- Purkinje cell toxicity ofβ-aminopropionitrile in the rat (2005) (9)
- Diffusion Tensor Imaging in Sporadic and Familial ( D 90 A SOD 1 ) Forms of Amyotrophic Lateral Sclerosis (2008) (9)
- Expression of the human groEL stress-protein homologue in the brain and spinal cord (1993) (9)
- Analysis of terms used for the diagnosis and classification of amyotrophic lateral sclerosis and motor neuron disease (2016) (9)
- Facial Onset Sensory and Motor Neuronopathy (2020) (8)
- Androgen-controlled specific gene expression in neuroblastoma cells (1995) (8)
- Motor Neuron Disease: Biology And Management (2011) (7)
- Purkinje cell toxicity of beta-aminopropionitrile in the rat. (1991) (6)
- Nutritional care of patients with motor neurone disease (2005) (6)
- Association of a Locus in the CAMTA 1 GeneWith Survival in PatientsWith Sporadic Amyotrophic Lateral Sclerosis (2016) (6)
- WITHDRAWN: Amino acids for amyotrophic lateral sclerosis / motor neuron disease. (2008) (5)
- Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy (2020) (5)
- Chapter 21 Disease-Modifying Therapies in Motor Neuron Disorders: The Present Position and Potential Future Developments (2003) (5)
- Altered network stability in progressive supranuclear palsy (2021) (4)
- Cortical function in progressive muscular atrophy and amyotrophic lateral sclerosis (1994) (4)
- RILUZOLE AND AMYOTROPHIC LATERAL SCLEROSIS. AUTHORS' REPLY (1996) (4)
- Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis (2015) (4)
- Chapter 8 Spinobulbar muscular atrophy (Kennedy's disease). (2007) (4)
- Riluzole and Motor Neurone Disease (2003) (3)
- Neuroprotection and Natural History in Parkinson Plus Syndromes (NNIPPS): Design and progress report of a clinical trial of the efficacy and safety of riluzole in Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA) (2002) (3)
- Corrigendum: An Overview of MicroRNAs as Biomarkers of ALS (2019) (3)
- Unusual Forms of Dementia (1994) (3)
- A novel somatodendritic marker defined by a peptide derived from the ALS2 protein (2004) (2)
- Cough Augmentation In Bulbar And Non-bulbar Motor Neuron Disease Patients (2001) (2)
- A virtual user involvement forum for people living with motor neuron disease (2003) (2)
- Neurite Orientation Dispersion and Density Imaging (NODDI) highlights axonal degeneration of the motor tracts as the core feature underlying Amyotrophic Lateral Sclerosis. (S53.008) (2017) (2)
- Neuroprotection and natural history (multiple system atrophy and progressive supranuclear palsy) (2004) (2)
- 017 Apathy is associated with altered cortical activation in pre-frontal regions during self-initiated actions (2010) (1)
- The challenges for policies and practices relating to MND health and social care. 13th International Symposium on ALS/ MND, Melbourne (2002) (1)
- Building user involvement in motor neurone disease: key lessons. (2004) (1)
- Erratum: Residual association of chromosome 9P21 SNPS with ALS after exclusion of C9ORF72 mutated cases (Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration (2012) 13 (18)) (2013) (1)
- Chapter 20. Amyotrophic Lateral Sclerosis (2008) (1)
- Living with Motor Neuron Disease (1995) (1)
- Clinical trials in pediatric ALS: a TRICALS feasibility study (2022) (1)
- Frontal lobe dysfunction in amyotrophic lateral (1996) (1)
- Protective effects of estrogens on polyglutamine-expanded androgen receptor aggregation in mice. (2003) (1)
- MMT vs MVIC (2003) (1)
- Using GFP-tagged neurofilament middle chain to investigate slow transport in cultured cortical neurons (2000) (1)
- Validity and reliability of the German language SF-36 health survey in patients with amyotrophic lateral sclerosis (2002) (1)
- Neurite Orientation Dispersion and Density Imaging (NODDI) demonstrates microstructural changes associated with Amyotrophic Lateral Sclerosis (2015) (1)
- Baseline disease characteristics (2004) (1)
- IMMUNO-MODULATION IN AMYOTROPHIC LATERAL SCLEROSIS - A PHASE II STUDY OF SAFETY AND ACTIVITY OF LOW DOSE INTERLEUKIN-2 (IMODALS study) (S3.006) (2017) (1)
- The role of superoxide-dismutase in protection against DNA damage induction following ionising radiation. (1995) (0)
- Advances in amyotrophic lateral sclerosis - Papers from the 10th International Symposium on Amyotrophic Lateral Sclerosis/Motor Neuron Disease held in Vancouver on November 15-17 November, 1999 - Preface (2000) (0)
- Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study (2014) (0)
- Chapter 63 – Sporadic Motor Neuron Degeneration (2005) (0)
- [C-11]-WAY100635 PET: A surrogate marker for MND? (2003) (0)
- Motor neuron disease presenting following prolonged diaphragm paralysis (2006) (0)
- Cortical localisation of neuropsychological impairment in amyotrophic lateral sclerosis (ALS): An [C-11] Flumazenil PET study (2005) (0)
- Atlas of the Human Brain and Spinal Cord (1984) (0)
- Motor Neuron Disease: Amyotrophic Lateral Sclerosis 98 (2013) (0)
- Preface (2001) (0)
- Preface (2000) (0)
- New insights into amyotrophic lateral sclerosis using quantitative magnetization transfer (qMT) (2017) (0)
- UvA-DARE ( Digital Academic Repository ) Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome (2017) (0)
- Picture quiz: Muscle weakness and wasting (2007) (0)
- Is cortical excitability abnormal in mnd? A study using pharmacological fMRI (2007) (0)
- 830 The role of superoxide dismutase in protection against radiation-induced DNA damage (1995) (0)
- Mean plasma ozanezumab concentration-time profiles following single (A) or two (B) IV infusions of ozanezumab. (2014) (0)
- PAW22 Does cortical atrophy take place after basal ganglia damage in multiple system atrophy and progressive supranuclear palsy? (2010) (0)
- Chapter 67 – Inherited Motor Neuron Degeneration (2005) (0)
- 13th International Sysmposium on ALS/ MND (2002) (0)
- 3 Famiiial Motor Neuron Disease (1995) (0)
- Programme for the 112th Meeting of the British Neuropathological Society, Institute of Child Health, London, UK, 5–7 January 2011 (2011) (0)
- Altered cortical activation in amyotrophic lateral sclerosis (ALS) differs in motor and extra-motor regions (2006) (0)
- Effect of the Kennedy Mutation of the Androgen Receptor on Gene Expression in Neuroblastoma Cells (1996) (0)
- Diffusion tensor imaging demonstrates differential involvement of brain structures in MSA and PSP (2004) (0)
- A simple FMRI paradigm for mapping the major components of the human motor system (1997) (0)
- Neurochemistry of Motor Neuron Disease (1995) (0)
- University of Groningen Mapping of Gene Expression Reveals CYP 27 A 1 as a Susceptibility Gene for Sporadic (2012) (0)
- Motor Neuron Disease and Its Management (1999) (0)
- Diffusion tensor imaging reveals white matter differences between sporadic and familial forms of amyotrophic lateral sclerosis (2008) (0)
- Modern Approaches to the Dementias. Part I: Etiology and Pathophysiology. Part II: Clinical and Therapeutic (1986) (0)
- Involving motor neurone disease users in practice and policy development (2002) (0)
- CORRELATION ANALYSIS OF NEURITE ORIENTATION DISPERSION & DENSITY IMAGING IN MND (2016) (0)
- Special Issue - Advances in Amyotrophic Lateral Sclerosis - Preface (2001) (0)
- Quality of life in patients with motor neuron disease treated with non-invasive ventilation (NIPPV) (2001) (0)
- The D90A SOD1 mutation in amyotrophic lateral sclerosis: Why are the Scandinavians protected? (2001) (0)
- Journal of the Neurological Sciences: Preface (2001) (0)
- ABNORMALITIES OF RESTING AND ACTIVATED CORTICAL BLOOD-FLOW IN AMYOTROPHIC-LATERAL-SCLEROSIS (ALS) AND PROGRESSIVE MUSCULAR-ATROPHY (PMA) (1993) (0)
- Progression of atypical parkinsonian syndromes: PROSPECT-M-UK study implications for clinical trials. (2023) (0)
- Building a virtual community in MND (2002) (0)
- CORTICAL MECHANISMS UNDERLYING THE PERCEPTION OF PHANTOM LIMBS IN HUMAN AMPUTEES (1994) (0)
- P20 Frontal white matter connections and cognitive change in amyotrophic lateral sclerosis: a DTI-tractography study (2012) (0)
- A Data-Driven Characterisation of the Evolution of White Matter Damage in Amyotrophic Lateral Sclerosis (2020) (0)
- White matter maps showing regions of significant decreased fractional anisotropy and increased mean diffusivity in MSA patients when compared to healthy controls and PD (Bonferroni corrected alpha = 0.0167). (2014) (0)
- DS1.1 Motorneurone degeneration: ALS and its clinical variants (2006) (0)
- MATTERS ARISING (1995) (0)
- White matter regions of fractional anisotropy changes between PSP, MSA, PD and HC. (2014) (0)
- Motor neurone disease. (1976) (0)
- Mutations in ANXA11 cause familial and sporadic amyotrophic lateral sclerosis (2017) (0)
- Cross-sectional clinical description of a large prospective cohort of patients with progressive supranuclear palsy or multiple system atrophy: The NNIPPS project (2003) (0)
- Neurodegenerative Diseases: An approach to the patient with motor neuron dysfunction (2005) (0)
- Cyclin dependent kinase 5 (CDK5) and neurodegeneration. (1999) (0)
- Diffusion tensor imaging demonstrates differential involvement of brainstem structures in progressive supranuclear palsy but not idiopathic Parkinson's disease (2004) (0)
- Disruption of thalamo-cortical loops predicts executive dysfunction in PSP (2006) (0)
- FP47-TH-05 Assessment of palliative care needs in people affected by advanced Parkinson's disease and related disorders (2009) (0)
- Cellular phosphorylation of neurofilament heavy-chain by multiple kinases (2000) (0)
- Reply to: Early white matter changes on diffusion tensor imaging in amyotrophic lateral sclerosis (2020) (0)
- LITHIUM CARBONATE IS NOT BENEFICIAL FOR PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS: RESULTS OF THE LICALS TRIAL [EUDRACT NUMBER: 2008-006891-31] (2012) (0)
- Natural History and Neuroprotection in Parkinson Plus Syndromes Parkinson Plus Scale (2014) (0)
- NR1: PATIENTS' REPORTED HEALTH STATUS AND UTILITIES FOR AMYOTROPHIC LATERAL SCLEROSIS (2000) (0)
- Neural control of voluntary breathing: Insight from functional neuroimaging (2006) (0)
- Neurite orientation dispersion and density imaging (NODDI) indices correlate with clinical markers of disease severity in amyotrophic lateral sclerosis (2017) (0)
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What Schools Are Affiliated With Peter Nigel Leigh?
Peter Nigel Leigh is affiliated with the following schools: