Paul S. Lietman
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Medical Philosophy
Paul S. Lietman's Degrees
- Masters Medicine University of California, San Francisco
- PhD Pharmacology University of California, San Francisco
Why Is Paul S. Lietman Influential?
(Suggest an Edit or Addition)Paul S. Lietman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. (1987) (1061)
- Acyclovir prophylaxis of herpes-simplex-virus infections. (1981) (535)
- Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. (1980) (388)
- Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. (1984) (381)
- The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia. (1984) (371)
- Risk factors for nephrotoxicity in patients treated with aminoglycosides. (1984) (369)
- Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults (2001) (330)
- Oral antibiotic treatment of right-sided staphylococcal endocarditis in injection drug users: prospective randomized comparison with parenteral therapy. (1996) (244)
- Controlled comparison of amikacin and gentamicin. (1977) (238)
- Multicenter collaborative trial of intravenous acyclovir for treatment of mucocutaneous herpes simplex virus infection in the immunocompromised host. (1982) (237)
- ISOLATION AND CHARACTERISATION OF RESISTANT HERPES SIMPLEX VIRUS AFTER ACYCLOVIR THERAPY (1982) (225)
- Serum vancomycin concentrations: reappraisal of their clinical value. (1994) (220)
- Risk factors for the development of auditory toxicity in patients receiving aminoglycosides. (1984) (211)
- Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients (1995) (173)
- Acyclovir prophylaxis against herpes simplex virus infection in patients with leukemia. A randomized, double-blind, placebo-controlled study. (1983) (163)
- Safety, Pharmacokinetics, and Antiretroviral Activity of Intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a Novel Anti-Human Immunodeficiency Virus (HIV) Therapy, in HIV-Infected Adults (1998) (160)
- CEPHALOTHIN PLUS AN AMINOGLYCOSIDE IS MORE NEPHROTOXIC THAN METHICILLIN PLUS AN AMINOGLYCOSIDE (1978) (143)
- Dextran sulfate is poorly absorbed after oral administration. (1989) (125)
- Aminoglycoside inhibition of a renal phosphatidylinositol phospholipase C. (1982) (121)
- Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans (1982) (114)
- Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination (1990) (95)
- Acute iron poisoning. A review. (1980) (93)
- Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. (1996) (91)
- Concentrations of Gentamicin and Amikacin in Human Kidneys (1976) (90)
- Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients. (1997) (90)
- PROBENECID AND ZIDOVUDINE METABOLISM (1989) (88)
- Increased risk of renal dysfunction due to interaction of liver disease and aminoglycosides. (1986) (82)
- Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure (1992) (81)
- Pharmacokinetics and tolerance of acyclovir, a new anti-herpesvirus agent, in humans (1982) (81)
- Cefotaxime compared with nafcillin plus tobramycin for serious bacterial infections. A randomized, double-blind trial. (1984) (80)
- Disposition of intravenous radioactive acyclovir (1981) (80)
- A double-blind controlled trial of anti-Pseudomonas chemotherapy of acute respiratory exacerbations in patients with cystic fibrosis. (1981) (76)
- Alterations of pigment epithelium in cystinosis. (1967) (74)
- Effect of renal failure on the pharmacokinetics of acyclovir. (1982) (70)
- The pharmacokinetics of amikacin in children. (1977) (69)
- Mass spectral analysis of glucuronides. (1973) (69)
- Evidence for luminal uptake of gentamicin in the perfused rat kidney. (1979) (67)
- Studies of risk factors for aminoglycoside nephrotoxicity. (1986) (67)
- Herpes simplex-1 virus thymidine kinase gene is unable to completely eliminate live, nonimmunogenic tumor cell vaccines. (1992) (65)
- Adult cystinosis--a benign disorder. (1966) (62)
- Gentamicin uptake by renal tubule brush border membrane vesicles. (1980) (62)
- Nephrotoxicity induced by gentamicin and amikacin. (1978) (60)
- Aminoglycoside Nephrotoxicity in Humans (1983) (54)
- Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infection (1998) (53)
- Chloramphenicol glucuronyl transferase: assay, ontogeny and inducibility. (1978) (51)
- Cystinosis. Plasma cystine and cysteine concentrations and the effect of D-penicillamine and dietary treatment. (1968) (50)
- Dantrolene sodium in children with spasticity. (1974) (50)
- Emergency treatment of asthma. A comparison of two treatment regimens. (1979) (49)
- PERICARDITIS IN JUVENILE RHEUMATOID ARTHRITIS. (1963) (49)
- Ultrastructural changes associated with reduced mitochondrial DNA and impaired mitochondrial function in the presence of 2'3'-dideoxycytidine (1992) (45)
- Effects of oral neomycin and kanamycin in chronic uremic patients: I. Urea metabolism. (1977) (45)
- Safety and Tolerability of Fluoroquinolones (2012) (44)
- Chloramphenicol and the neonate--1979 view. (1979) (44)
- Chloramphenicol: an Enzymological Microassay (1976) (42)
- IRON POISONING: ANOTHER ENERGY CRISIS (1974) (41)
- Edema associated with ibuprofen therapy. (1977) (41)
- Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. A prospective, randomized, double-blind study. (1980) (40)
- Influence of hemodialysis on acyclovir pharmacokinetics in patients with chronic renal failure. (1982) (40)
- Mitochondrial protein synthesis: inhibition by emetine hydrochloride. (1971) (39)
- Fluoroquinolone toxicities. An update. (1995) (38)
- Metabolic fate of radioactive acyclovir in humans. (1982) (38)
- Neomycin inhibition of adenosine triphosphatase: evidence for a neomycin-phospholipid interaction (1980) (37)
- Time course of interferon levels, antiviral state, 2',5'-oligoadenylate synthetase and side effects in healthy men. (1987) (37)
- Autoradiographic Localization of [3H]Gentamicin in the Proximal Renal Tubules of Mice (1979) (36)
- Comparative cost effectiveness of gentamicin and tobramycin. (1984) (35)
- PROPHYLAXIS: A STRATEGY TO MINIMISE ANTIVIRAL RESISTANCE (1984) (35)
- Intranuclear accumulation of subgenomic noninfectious human cytomegalovirus DNA in infected cells in the presence of ganciclovir (1991) (34)
- Pharmacology of dantrolene sodium in children. (1974) (33)
- A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team. (1995) (31)
- A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered- dose inhalers. (2002) (30)
- Pharmacokinetic studies of prednisolone in children (1978) (28)
- Effect of furosemide on aminoglycoside-induced nephrotoxicity and auditory toxicity in humans (1983) (28)
- Commentary: a reappraisal of digitalis for infants with left-to-right shunts and "heart failure". (1978) (27)
- Familial hyperglycinuria. New defect in renal tubular transport of glycine and imino acids. (1973) (27)
- Lipid patterns in Niemann-Pick disease. (1961) (26)
- What is an antibiotic? (1986) (25)
- Zidovudine with probenecid: a warning (1990) (25)
- Relationship of formulation and dosing interval to fluctuation of serum theophylline concentration in children with chronic asthma (1981) (24)
- Acyclovir clinical pharmacology. An overview. (1982) (24)
- Rapid acyclovir radioimmunoassay, using charcoal adsorption (1982) (24)
- A study of potential vestibulotoxic effects of once daily versus thrice daily administration of tobramycin (1987) (22)
- A Phase I/II Evaluation of Oral L‐2‐Oxothiazolidine‐4‐Carboxylic Acid in Asymptomatic Patients Infected with Human Immunodeficiency Virus (1998) (22)
- OPTIC NEURITIS IN CYSTIC FIBROSIS OF THE PANCREAS. ROLE OF CHLORAMPHENICOL THERAPY. (1964) (22)
- Clinical pharmacology: foscarnet. (1992) (20)
- Overdoses of Chloramphenicol (1975) (20)
- Ex vivo zidovudine (AZT) treatment of CD34+ bone marrow progenitors causes decreased steady state mitochondrial DNA (mtDNA) and increased lactate production (2004) (20)
- Biologic effects after a single dose of poly(I):poly(C12U) in healthy volunteers (1993) (19)
- Clinical Pharmacokinetics of 1-[((S)-2-Hydroxy-2-Oxo-1,4,2-Dioxaphosphorinan-5-yl)methyl]cytosine in Human Immunodeficiency Virus-Infected Patients (1999) (19)
- Reference Values for Serial Vestibular Testing (1986) (18)
- Ceftriaxone compared with cefotaxime for serious bacterial infections. (1989) (18)
- Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers (1987) (17)
- Continuous sampling as a pharmacokinetic tool (1977) (17)
- Fluoroquinolone Toxicities (2012) (17)
- Induction of chemoprotective phase 2 enzymes by ginseng and its components. (2009) (16)
- Iron and deferoxamine in lymphocyte blastogenesis. (1980) (16)
- Indolenines. Reduction by a dihydropyridine and addition to thiols. (1967) (16)
- Double-Blind Comparison of Cefamandole and Penicillin in Pneumococcal Pneumonia (1978) (15)
- Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion in in vitro cell culture perfusion system (1994) (15)
- Antiviral Activity of Inhibitors of Pyrimidine De-Novo Biosynthesis (1996) (14)
- Cefotaxime vs nafcillin and tobramycin for the treatment of serious infection. Comparative cost-effectiveness. (1986) (14)
- Inhibition of cytomegalovirus by rifampin. (1972) (12)
- Effect of dipyridamole on zidovudine pharmacokinetics and short-term tolerance in asymptomatic human immunodeficiency virus-infected subjects (1994) (12)
- Oral chloramphenicol therapy. (1981) (12)
- Parenteral trimethoprim-sulfamethoxazole and carbenicillin as empiric therapy for neutropenic patients with cancer. (1982) (11)
- Enzymatic acylation of phenylalanyl transfer ibonucleic acids from mitochondri and cytosol of rat liver. (1968) (11)
- Pharmacokinetics of Antimicrobial Drugs in Cystic Fibrosis : β-Lactam Antibiotics (1988) (10)
- The bazard of narcotics in the home: Accidental ingestion by infants and young children (1971) (10)
- Prophylactic acyclovir therapy and herpes simplex. (1984) (9)
- Exchange transfusion in acute chloramphenicol toxicity. (1981) (9)
- Anticytomegaloviral activity of methotrexate associated with preferential accumulation of drug by cytomegalovirus-infected cells (1996) (9)
- Acyclovir concentrations and tolerance during repetitive administration for 18 days. (1982) (8)
- 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81) potently inhibits human cytomegalovirus replication and potentiates the antiviral effects of ganciclovir (1993) (8)
- A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants. (1973) (7)
- Herbal Medicine Development: A Plea for a Rigorous Scientific Foundation (2012) (7)
- Apparent deficiency of glutathionine in the PBMC's of people with AIDS depends on method of expression. (1995) (6)
- IDENTIFICATION OF L-CYSTINE CRYSTALS IN BONE MARROW BY X-RAY DIFFRACTION. (1965) (6)
- Chloramphenicol metabolism in isolated rat hepatocytes. (1978) (6)
- Methicillin-associated fever. A double-blind comparison of methicillin from two manufacturers. (1974) (5)
- Letter: Overdoses of chloramphenicol. (1975) (5)
- Treatment and prevention of virus infections in immunosuppressed patients. (1985) (5)
- Behavioral Sciences and Health Care (1975) (5)
- Suppression of graft-versus-host reactions by D- and L-chloramphenicol. (1976) (5)
- The use of mild analgesics in pregnancy (1982) (4)
- Losing the opportunity to study influenza drugs. (2010) (4)
- The effect of co‐trimoxazole on thymidine uptake by transforming human lymphocytes in vitro (1976) (4)
- Lack of evidence for interaction between tobramycin and shock in their effect on renal function (1985) (4)
- The effect of increasing gastric pH upon the bioavailability of orally-administered foscarnet. (1998) (4)
- Modulation of alpha-interferon's antiviral and clinical effects by aspirin, acetaminophen, and prednisone in healthy volunteers. (1995) (3)
- Toxicity of gentamicin and tobramycin. (1980) (3)
- Pharmacokinetics of antimicrobial drugs in cystic fibrosis. Beta-lactam antibiotics. (1988) (3)
- Clinical evaluation of amoscanate in healthy male volunteers. (1986) (3)
- Predicting aminoglycoside nephrotoxicity. (1986) (3)
- Effect ofFurosemide on Aminoglycoside-Induced Nephrotoxicity andAuditory Toxicity inHumans (1983) (3)
- Commentary: assessment of amikacin for pediatric usage. (1977) (3)
- Pharmacologic effects on developing enzyme systems. (1972) (2)
- Effect of folate and folinate on3H-thymidine incorporation by transforming human lymphocytes in vitro (1977) (2)
- Methodological issues in AIDS clinical trials. Discussion. Design of clinical trials--approaches to clinical trials design. (1990) (2)
- The hazard of narcotics in the home: accidental ingestion by infants and young children. (1971) (2)
- Bioavailability of Oral Pyridostigmine and Inhibition of Red Blood Cell Acetylcholinesterase by Oral and Intravenous Pyridostigmine (1989) (2)
- The in vitro effect of trimethoprim on blastogenic transformation of human peripheral blood lymphocytes. (1977) (2)
- Peripheral and optic neuritis in a patient with hemoglobin SC disease during treatment of salmonella osteomyelitis with chloramphenicol. (1977) (2)
- The activity of Brequinar, an inhibitor of de novo pyrimidine biosynthesis, against human cytomegalovirus replication (1991) (2)
- Tubular uptake of gentamicin by the intact kidney (1978) (2)
- Effect of 'high-dose' amikacin in children. (1984) (2)
- Intravenous dextran sulfate (DS) increases circulating HIV antigen levels in patients with ARC or AIDS (1991) (1)
- METHICILLIN-ASSOCIATED FEVER (1975) (1)
- Neomycin Inhibition ofAdenosine Triphosphatase: Evidence for aNeomycin-Phospholipid Interaction (1980) (1)
- Overview: issues concerning the pharmacology of multiple drug regimens. (1996) (1)
- FEBRILE REACTIONS AFTER METHICILLIN (1974) (1)
- Quinolones in pediatrics: Viewpoint of a clinical pharmacologist (1996) (1)
- Selective uptake of [125I]iododeoxycytidine in cells infected with herpes simplex virus type 1. (1981) (1)
- Effects of 2′3′-dideoxycytidine (DDC) an anti HIV-1 nucleoside analogue on mitochondrial biogenesis, structure and function (1991) (1)
- 3′-azido-2′3′-dideoxythymidine (AZT) inhibits proliferation of normal bone marrow progenitor cells by reducing mitochondrial biogenesis (1991) (1)
- Diphenylhydantoin diazepam interactions: a pharmacokinetic analysis (1975) (1)
- Pharmacology of antiretroviral drugs. Lessons learned to date. (1990) (1)
- Treatment of Herpes Simplex Virus Infections in Immunosuppressed Patients (1988) (1)
- Inhibition by trimethoprim of some effects of epidermal growth factor on human fibroblasts in tissue culture. (1976) (1)
- Clinical Research, Ethics of Clinical Research in China (2012) (1)
- Evaluation of the Pharmacokinetics and Tolerance of Allopurinol Riboside in Human Volunteers. (1984) (0)
- Editor's column: Commentary: clotrimazole. (1976) (0)
- Single-Dose Absorption and Pharmacokinetics of WR 6026. Phase 1 (1988) (0)
- USE OF RADIOIMMUNOASSAY TO STUDY DIPHENYLHYDANTOIN PHARMACOKINETICS IN CHILDREN (1974) (0)
- Lack of beta-oxidation defects in human immunodeficiency virus-positive subjects with and without chronic zidovudine exposure. (1996) (0)
- Reduction of cytochrome oxidase activity by chloramphenicol in transforming murine lymphocytes (1975) (0)
- Single-Bolus Dose and Continuous Infusion in In Vitro (0)
- Pharmacology of Antiretroviral Drugs (1990) (0)
- Book ReviewAntimicrobial Therapy (1981) (0)
- Aminoglycoside and polyamine inhibition of a renal phosphotidylinositol phospholipase (1982) (0)
- Deperoxamine and iron in lymphocyte blastogenesis (1977) (0)
- Letter: Methicillin-associated fever. (1975) (0)
- Mechanism of chloramphenicol induced immunosuppression (1976) (0)
- Phase I Clinical Pharmacology Studies (1993) (0)
- [Nephrotoxicity of gentamycin and tobramycin combined with methicillin or cephalothin]. (1978) (0)
- About this journal. (2012) (0)
- Letter: Iron poisoning: another energy crisis. (1974) (0)
- Clinical Pharmacology Studies. Phase 1. (1987) (0)
- The chemostat as an in vitro model for assessing the influence of pharmacokinetics on aminoglycoside antibacterial activity (1978) (0)
- CHLORAMPHENICOL IN HÆMOPHILUS ENDOCARDITIS (1977) (0)
- Letter: Febrile reactions after methicillin. (1974) (0)
- Antiviral chemotherapy. (1988) (0)
- Gentamicin uptake by rabbit renal proximal tubule brush border membranes (1979) (0)
- Letter to the editorEditorial correspondenceReply (1975) (0)
- Clinical andpharmacokinetic evaluation of nafcillin in infants and children (1978) (0)
- Requirement of Thiols in the Adenosine-Diphosphate Ribosylaton of Elongaton Factor-2 by Pseudomonas Aeruginosa Exotoxin A (1981) (0)
- Pharmacokinetics and Pharmacodynamics of Sustained Low-Dose Intravenous Infusions of Pyridostigmine (1993) (0)
- Effect of pregnancy on phenytoin metabolism by rat liver in vitro (1976) (0)
- Screening for Beta‐Oxidation Abnormalities as an Indicator of Drug‐Induced Impaired Mitochondrial Function in People Receiving Zidovudine (ZDV) (1996) (0)
- Iron Poisoning-Reply (1981) (0)
- Antiviral drugs: where do we stand in 1982? (1983) (0)
- The relationship between plasma levels of aminoglycoside and nephrotoxicity (1979) (0)
- Safety Tolerance Pharmacokinetics and Pharmacodynamics of Intravenous Pyridostigmine in Healthy Men and the Influence of Food on Oral Pyridostigmine Pharmacokinetics (1991) (0)
- AMINOGLYCOSIDE NEPHROTOXICITY (1977) (0)
- Development of New Medicines Ethical Questions : Proceedings of a Conference Sponsored by Foundation Rhône-Poulenc Sauté, Held in Paris, 2 December 1988 (1989) (0)
- The role of cefamandole in the treatment of (1981) (0)
- AIDS therapies on the horizon (1992) (0)
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