Peter S. Tobias
#155,244
Most Influential Person Now
Peter S. Tobias's AcademicInfluence.com Rankings
Peter S. Tobiasbiology Degrees
Biology
#11917
World Rank
#15351
Historical Rank
Immunology
#782
World Rank
#805
Historical Rank
Molecular Biology
#1886
World Rank
#1915
Historical Rank
Biochemistry
#2002
World Rank
#2143
Historical Rank
Download Badge
Biology
Peter S. Tobias's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Chemistry Stanford University
Why Is Peter S. Tobias Influential?
(Suggest an Edit or Addition)Peter S. Tobias's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. (1990) (4205)
- Structure and function of lipopolysaccharide binding protein. (1990) (1716)
- Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. (1995) (1542)
- Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. (1993) (876)
- CD14 is a pattern recognition receptor. (1994) (767)
- Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism (2001) (739)
- Lipopolysaccharide Is in Close Proximity to Each of the Proteins in Its Membrane Receptor Complex (2001) (718)
- Recognition of gram-negative bacteria and endotoxin by the innate immune system. (1999) (622)
- Modulation of atherosclerosis in mice by Toll-like receptor 2. (2005) (561)
- Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum (1986) (555)
- Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages (1989) (385)
- Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. (1989) (355)
- Lipopolysaccharide Binding Protein-mediated Complexation of Lipopolysaccharide with Soluble CD14 (*) (1995) (338)
- Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. (1993) (327)
- Lipopolysaccharide (LPS) Signal Transduction and Clearance (1995) (281)
- TLR2 Is Constitutively Expressed within the Kidney and Participates in Ischemic Renal Injury through Both MyD88-Dependent and -Independent Pathways1 (2007) (270)
- MD-2 binds to bacterial lipopolysaccharide. (2001) (264)
- Toll-Like Receptor 4, But Not Toll-Like Receptor 2, Is a Signaling Receptor for Escherichia and Salmonella Lipopolysaccharides1 (2000) (262)
- Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein (1992) (261)
- Recognition of endotoxin by cells leading to transmembrane signaling. (1994) (259)
- Double-stranded RNA-mediated TLR3 activation is enhanced by CD14. (2006) (258)
- Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs. (1992) (232)
- Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events (2008) (229)
- A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis. (1988) (225)
- Plasma lipopolysaccharide (LPS)-binding protein. A key component in macrophage recognition of gram-negative LPS. (1992) (224)
- Adaptation to bacterial lipopolysaccharide controls lipopolysaccharide-induced tumor necrosis factor production in rabbit macrophages. (1990) (212)
- Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes. (1992) (207)
- Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin. (1993) (189)
- CD14 receptor-mediated uptake of nonopsonized Mycobacterium tuberculosis by human microglia (1995) (180)
- TLR4 Is the Signaling but Not the Lipopolysaccharide Uptake Receptor12 (2004) (175)
- Lipopolysaccharide binding protein and CD14 in LPS dependent macrophage activation. (1993) (175)
- Lactoferrin Inhibits the Endotoxin Interaction with CD14 by Competition with the Lipopolysaccharide-Binding Protein (1998) (172)
- A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation (1993) (159)
- Toll‐like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS‐responses (2004) (157)
- Emerging role of Toll-like receptors in atherosclerosis Published, JLR Papers in Press, November 1, 2008. (2009) (157)
- Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. (2012) (151)
- Analysis of lipopolysaccharide binding by CD14. (1993) (149)
- Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes. (2011) (149)
- Two Lipoproteins Extracted from Escherichia coli K-12 LCD25 Lipopolysaccharide Are the Major Components Responsible for Toll-Like Receptor 2-Mediated Signaling1 (2002) (148)
- Participation of lipopolysaccharide-binding protein in lipopolysaccharide-dependent macrophage activation. (1992) (143)
- Asthma and endotoxin: lipopolysaccharide-binding protein and soluble CD14 in bronchoalveolar compartment. (1996) (139)
- Priming of Polymorphonuclear Granulocytes by Lipopolysaccharides and Its Complexes With Lipopolysaccharide Binding Protein and High Density Lipoprotein (1990) (137)
- Phagocytosis of Gram‐negative bacteria by a unique CD14‐dependent mechanism (1997) (134)
- Knockout of Toll-Like Receptor-2 Attenuates Both the Proinflammatory State of Diabetes and Incipient Diabetic Nephropathy (2011) (131)
- Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling. (2003) (126)
- Cross-linking of lipopolysaccharide (LPS) to CD14 on THP-1 cells mediated by LPS-binding protein. (1993) (123)
- Lipopolysaccharide binding protein expression in primary human hepatocytes and HepG2 hepatoma cells. (1994) (123)
- Lipopolysaccharide (LPS)-binding Proteins BPI and LBP Form Different Types of Complexes with LPS* (1997) (119)
- Flow-Dependent Regulation of Endothelial Toll-Like Receptor 2 Expression Through Inhibition of SP1 Activity (2004) (117)
- Soluble CD14-mediated cellular responses to lipopolysaccharide. (2000) (108)
- Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro. (1994) (107)
- Biosynthesis of lipopolysaccharide-binding protein in rabbit hepatocytes. (1990) (103)
- Thematic review series: The Immune System and Atherogenesis. Paying the price for pathogen protection: toll receptors in atherogenesis Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.R400015-JLR200 (2005) (103)
- Cell Activation Mediated by Glycosylphosphatidylinositol-Anchored or Transmembrane Forms of CD14 (1998) (100)
- Orphan Nuclear Receptor Nur77 Is Involved in Caspase-independent Macrophage Cell Death (2003) (96)
- Lipopolysaccharide (LPS) recognition in macrophages. Participation of LPS-binding protein and CD14 in LPS-induced adaptation in rabbit peritoneal exudate macrophages. (1993) (94)
- MD-2 binds to bacterial lipopolysaccharide (2000) (93)
- Endotoxin interactions with lipopolysaccharide-responsive cells. (1999) (89)
- Cytoplasmic Domain-mediated Dimerizations of Toll-like Receptor 4 Observed by β-Lactamase Enzyme Fragment Complementation* (2004) (84)
- Lipopolysaccharide (LPS)-binding Protein Inhibits Responses to Cell-bound LPS* (2003) (78)
- Lipopolysaccharide binding protein and CD14 modulate the synthesis of platelet-activating factor by human monocytes and mesangial and endothelial cells stimulated with lipopolysaccharide. (1995) (76)
- Lipopolysaccharide (LPS)-binding protein in human serum determines the tumor necrosis factor response of monocytes to LPS. (1994) (76)
- Control of lipopolysaccharide-high-density lipoprotein interactions by an acute-phase reactant in human serum (1985) (72)
- Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking. (1990) (71)
- MyD88 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-Like Receptors 2 and 4 (2011) (71)
- The CD14 differentiation antigen mediates the development of endotoxin responsiveness during differentiation of mononuclear phagocytes (1994) (70)
- Interactions of lipopolysaccharide with neutrophils in blood via CD14 (1993) (65)
- Lipopolysaccharide (LPS) binding protein, truncated at Ile-197, binds LPS but does not transfer LPS to CD14. (1994) (62)
- Structure-Function Analysis of CD14 as a Soluble Receptor for Lipopolysaccharide* (2000) (57)
- Enhancement of murine macrophage binding of and response to bacterial lipopolysaccharide (LPS) by LPS‐binding protein (1992) (51)
- Lipopolysaccharide dependent cellular activation. (1997) (50)
- A new model of macrophage stimulation by bacterial lipopolysaccharide. (1990) (49)
- Neutrophil adherence induced by lipopolysaccharide in vitro. Role of plasma component interaction with lipopolysaccharide. (1992) (48)
- Structural determinants for the interaction of lipopolysaccharide binding protein with purified high density lipoproteins: role of apolipoprotein A-I. (1997) (48)
- Kinetics and equilibriums of the reaction of pyridoxal 5'-phosphate with ethylenediamine to form Schiff bases and cyclic geminal diamines. Evidence for kinetically competent geminal diamine intermediates in transimination sequences (1975) (48)
- Toll-like receptors and atherosclerosis (2006) (47)
- Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists[S] (2012) (47)
- Urinary soluble CD14 mediates human proximal tubular epithelial cell injury induced by LPS. (2002) (47)
- Activation of endothelial cells by endotoxin: direct versus indirect pathways and the role of CD14. (1995) (47)
- Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein. (2005) (46)
- Regulatory mechanisms of host responsiveness to endotoxin (lipopolysaccharide). (1991) (46)
- Control of lipopolysaccharide-high density lipoprotein binding by acute phase protein(s). (1983) (45)
- Tumor necrosis factor-alpha and interleukin-1 beta mediate human endothelial cell activation in blood at low endotoxin concentrations. (1995) (44)
- INTERACTIONS OF BACTERIAL LIPOPOLYSACCHARIDE WITH ACUTE PHASE RABBIT SERUM (1982) (42)
- Purification and characterization of murine lipopolysaccharide-binding protein (1993) (41)
- Observation of two procrosins in extracts of human spermatozoa. (1977) (38)
- The LPS2 mutation in TRIF is atheroprotective in hyperlipidemic low density lipoprotein receptor knockout mice (2013) (37)
- The toll of Toll-like receptors, especially toll-like receptor 2, on murine atherosclerosis. (2007) (36)
- Lipopolysaccharide-binding protein and CD14 in the lipopolysaccharide-dependent activation of cells. (1994) (34)
- Lipopolysaccharide binding protein in acute pancreatitis (2000) (31)
- A Potential Suppressive Effect of Natural Antisense IL-1β RNA on Lipopolysaccharide-Induced IL-1β Expression (2013) (29)
- Bath exposure of Atlantic halibut (Hippoglossus hippoglossus L.) yolk sac larvae to bacterial lipopolysaccharide (LPS): absorption and distribution of the LPS and effect on fish survival. (2000) (28)
- Birefringence of muscle proteins and the problem of structural birefringence. (1968) (28)
- Endotoxin, endotoxin-binding protein, and soluble CD14 are present in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. (1994) (28)
- Toll-like receptors in atherosclerosis. (2007) (27)
- .alpha.-Chymotrypsin-catalyzed hydrolysis of lactones (1969) (26)
- Epithelial p38α Controls Immune Cell Recruitment in the Colonic Mucosa (2010) (25)
- Application of β-Lactamase Enzyme Complementation to the High-Throughput Screening of Toll-Like Receptor Signaling Inhibitors (2007) (25)
- The TNF Family Member 4-1BBL Sustains Inflammation by Interacting with TLR Signaling Components During Late-Phase Activation (2013) (25)
- Mutational Analysis of Membrane and Soluble Forms of Human MD-2* (2006) (24)
- Double-Stranded RNA-Mediated TLR 3 Activation Is Enhanced by CD 14 (22)
- LPS and LAM activation of the U373 astrocytoma cell line: Differential requirement for CD14 (2000) (19)
- Membrane-anchored forms of lipopolysaccharide (LPS)-binding protein do not mediate cellular responses to LPS independently of CD14. (1999) (18)
- TLR2 in murine atherosclerosis (2008) (18)
- Roles for LBP and soluble CD14 in cellular uptake of LPS. (1998) (14)
- MyD 88 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-Like Receptors 2 and 4 (2011) (13)
- Alkaline hydrolysis of 5-nitrocoumaranone. Method for determining the intermediacy of carbanions in the hydrolysis of esters with labile .alpha. protons (1969) (11)
- LPS binding protein and CD14 in the LPS dependent activation of cells. (1994) (11)
- Fluorescence resonance energy transfer analysis of lipopolysaccharide in detergent micelles. (1996) (11)
- Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling (2003) (11)
- Lipopolysaccharide-binding proteins of Limulus amebocyte lysate (1993) (10)
- The extraction of acrosin from human spermatozoa. (1976) (10)
- Isolation, partial characterization, and concentration in experimental sepsis of baboon lipopolysaccharide-binding protein. (2000) (10)
- Circular dichroism studies of chymotrypsin and its derivatives. Correlation of changes in dichroic bands with deacylation. (1969) (10)
- Regulation of the host response to bacterial lipopolysaccharides. (1984) (10)
- TLR2 is Required for the Altered Transcription of p75NGF Receptors in Gram Positive Infection (2006) (9)
- CD14 dependent mechanisms of cell activation. (1998) (9)
- Lipopolysaccharide-Binding Protein and CD14 (2003) (8)
- Mechanisms of Cellular Activation by Endotoxin1 (1995) (8)
- Serum‐Dependence of LPS‐Induced Neurotoxicity in Rat Cortical Neurons (2002) (8)
- The Role of the Macrophage in the Host Response to Bacterial Endotoxins (1983) (5)
- Independent Pathways Injury through Both MyD 88-Dependent and Kidney and Participates in Ischemic Renal TLR 2 Is Constitutively Expressed within the Mackman and (2007) (4)
- Interactions of bacterial lipopolysaccharides with serum proteins. (1988) (3)
- Interactions between endotoxin and endotoxin-binding protein (1994) (2)
- 347 Serum-derived lipopolysaccharide (LPS) binding factors enhance the LPS-mediated induction of type 1 plasminogen activator inhibitor (PAI-1) in endothelial cells (1988) (2)
- Cell surface binding of LBP—LPS complexes to a protein component distinct from CD14 (1999) (2)
- Circular Dichroism Studies of Chymotrypsin and Its Derivatives (2003) (2)
- Corrigendum to "Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes" [Cytokine 55 (2011) 441-445] (2011) (2)
- Molecular Mechanisms of Lipopolysaccharide-Induced Cytokine Production by Monocytes (1993) (1)
- LBP does not substitute for CD14 as a signaling membrane bound LPS receptor (1999) (1)
- The use of small molecule probes to study spatially separated stimulus-induced signaling pathways. (2012) (1)
- Understanding how macrophages recognize bacterial lipopolysaccharide (1992) (1)
- Abstract: 143 ENDOTHELIAL CELL TOLL-LIKE RECEPTOR EXPRESSION AND MACROPHAGE ACCUMULATION ARE INCREASED ONLY IN REGIONS OF DISTURBED BLOOD FLOW IN THE MOUSE AORTA (2009) (1)
- TLRs in disease (2008) (1)
- Metoder Science Foer foerhindrande The compositions of the symtomer of sepsis. (1992) (0)
- Abstract: S2-4 OPTICAL ANALYSIS OF TLR FUNCTION IN ATHEROMA (2009) (0)
- Method and compositions that improve the symptoms of sepsis. (1990) (0)
- Development of an Immunoassay for Bacterial Endotoxins (1983) (0)
- Lipopolysaccharide-Binding Protein (2020) (0)
- Not Mediate Cellular Responses to LPS DoLipopolysaccharide ( LPS )-Binding Protein Membrane-Anchored Forms of (1999) (0)
- A ROLE FOR LBP IN INTERNALIZATION OF LPS AND PHAGOCYTOSIS OF GRAM NEGATIVE BACTERIA.: 83 (1997) (0)
- Abstract 42: Monocyte Tissue Factor-Dependent Activation of Coagulation in Hypercholesterolemic Mice and Monkeys Is Inhibited by Simvastatin (2012) (0)
- Signaling by Toll-Like Receptors (2008) (0)
- Regulation of 4-1BBL-mediated inflammation at the late phase of TLR response (P1228) (2013) (0)
- Glycosyl-phosphatidylinositol-an chored orintegral membraneforms ofCD14mediate identical cellular responses toendotoxin (1993) (0)
- A role for LBP in cellular uptake of LPS (1996) (0)
- Human endothelial cell responses to endotoxin are dramatically enhanced by human blood (1994) (0)
- Abstract 1356: Endothelial Cell Toll-Like Receptor 2 Expression And Macrophage Number Are Increased At Sites Of Disturbed Blood Flow In The Mouse Aorta (2006) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Peter S. Tobias?
Peter S. Tobias is affiliated with the following schools:
