Pierre Sirois
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Biology
Pierre Sirois's Degrees
- PhD Biochemistry Université de Montréal
- Masters Molecular Biology McGill University
Why Is Pierre Sirois Influential?
(Suggest an Edit or Addition)Pierre Sirois's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Growth regulatory properties of endothelins (1993) (366)
- Endothelins: circulating plasma levels and presence in other biologic fluids. (1993) (224)
- RELEASE OF MEDIATORS OF ANAPHYLAXIS: INHIBITION OF PROSTAGLANDIN SYNTHESIS AND THE MODIFICATION OF RELEASE OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS AND HISTAMINE (1978) (180)
- Leukotriene B4 induces human suppressor lymphocytes. (1982) (164)
- Leukotriene B4 augments human natural cytotoxic cell activity. (1983) (154)
- Endothelin A receptor blockade causes adverse left ventricular remodeling but improves pulmonary artery pressure after infarction in the rat. (1998) (119)
- Transformation of arachidonic acid in leukocytes. Isolation and structural analysis of a novel dihydroxy derivative. (1981) (119)
- Leukotrienes: a major step in the understanding of immediate hypersensitivity reactions. (1981) (117)
- Effects of endothelin‐1 on vascular permeability in the conscious rat: interactions with platelet‐activating factor (1991) (111)
- Studies on inflammatory response induced by Ehrlich tumor in mice peritoneal cavity (1990) (93)
- THE RELEASE OF PROSTAGLANDINS AND THROMBOXANES FROM GUINEA‐PIG LUNG BY SLOW REACTING SUBSTANCE OF ANAPHYLAXIS, AND ITS INHIBITION (1978) (91)
- The role of kinin receptors in cancer and therapeutic opportunities. (2014) (91)
- Pharmacological activity of leukotrienes A4, B4, C4 and D4 on selected guinea-pig, rat, rabbit and human smooth muscles. (1981) (91)
- ET(B) receptor and nitric oxide synthase blockade induce BQ-123-sensitive pressor effects in the rabbit. (1997) (85)
- Endothelin-1 induces prostacyclin release from bovine aortic endothelial cells. (1991) (84)
- The action of leukotriene B4 (LTB4) on the lung. (1980) (80)
- Nitric oxide modulates vascular permeability in the rat coronary circulation (1993) (79)
- Enhancement by endothelin‐1 of microvascular permeability via the activation of ETA receptors (1993) (78)
- Vascular responses to endothelin‐1 following inhibition of nitric oxide synthesis in the conscious rat (1993) (76)
- PAF increases vascular permeability in selected tissues: effect of BN-52021 and L-655,240. (1988) (75)
- Automated on-line extraction and profiling of lipoxygenase products of arachidonic acid by high-performance liquid chromatography. (1990) (74)
- Iron homeostasis in osteoporosis and its clinical implications (2012) (69)
- Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice (2003) (69)
- Asbestos-induced lung injury in the sheep model: the initial alveolitis. (1983) (68)
- Sequential analysis of the bronchoalveolar milieu in conscious sheep. (1981) (65)
- Myocardial alpha1-adrenoceptor: inotropic effect and physiologic and pathologic implications. (1997) (65)
- The antiangiogenic agent neovastat (AE-941) inhibits vascular endothelial growth factor-mediated biological effects. (2002) (63)
- Characterization of ATP-diphosphohydrolase activities in the intima and media of the bovine aorta: evidence for a regulatory role in platelet activation in vitro. (1992) (62)
- Endothelin-1 enhances vascular permeability in conscious rats: role of thromboxane A2. (1992) (60)
- From slow reacting substance of anaphylaxis (SRS-A) to leukotriene D4 (LTD4). (1980) (58)
- The lung parenchymal strip as a sensitive assay for leukotriene B4. (1981) (55)
- Evidence for a mediator role of thromboxane A2 in the myotropic action of leukotriene B4 (LTB4) on the guinea-pig lung. (1982) (55)
- Role of eicosanoids in PAF‐induced increases of the vascular permeability in rat airways (1990) (54)
- Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins. (2001) (53)
- Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor. (1988) (49)
- Role of bradykinin B(1) receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice. (2002) (46)
- Neurohormonal activation in severe heart failure: relations to patient death and the effect of treatment with flosequinan. (2000) (45)
- Induction by endothelin‐1 of epithelium‐dependent relaxation of guinea‐pig trachea in vitro: role for nitric oxide (1993) (45)
- Lung is an important source of atrial natriuretic factor in experimental cardiomyopathy. (1989) (44)
- Endothelin-1 enhances vascular permeability in the rat heart through the ETA receptor. (1992) (44)
- Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions. (1992) (42)
- Changes in vasoconstrictive hormones, natriuretic peptides, and left ventricular remodeling soon after anterior myocardial infarction. (2001) (41)
- Phosphoramidon blocks big‐endothelin‐1 but not endothelin‐1 enhancement of vascular permeability in the rat (1992) (40)
- Kinin B1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice (2003) (40)
- Enhanced dermal and retinal vascular permeability in streptozotocin-induced type 1 diabetes in Wistar rats: blockade with a selective bradykinin B1 receptor antagonist (2005) (40)
- Endothelin induces thromboxane release and contraction of isolated guinea-pig airways. (1990) (40)
- Inhibitory effect of a novel bradykinin B1 receptor antagonist, R-954, on enhanced vascular permeability in type 1 diabetic mice. (2002) (40)
- Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice (2005) (39)
- Human natural cytotoxic cell activity: enhancement by leukotrienes (LT) A4, B4 and D4, but not by stereoisomers of LTB4 or HETES. (1984) (39)
- Hyperalgesia in non-obese diabetic (NOD) mice: a role for the inducible bradykinin B1 receptor. (2005) (39)
- Release of immunoreactive atrial natriuretic factor from the isolated perfused rat lung (1987) (38)
- Differential modulation of murine lung inflammation by bradykinin B1 and B2 selective receptor antagonists. (2003) (38)
- Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis (2011) (37)
- Involvement of bradykinin B1 and B2 receptors in pulmonary leukocyte accumulation induced by Sephadex beads in guinea pigs. (1999) (35)
- Biological and Biomedical Applications of Engineered Nucleases (2013) (35)
- Inactivation of slow reacting substance of anaphylaxis (SRS-A) by lipoxidase. (1979) (34)
- Early lung events following low-dose asbestos exposure. (1981) (34)
- Pharmacological modulation of endothelin‐induced contraction of guinea‐pig isolated airways and thromboxane release (1991) (34)
- Phospholipase A activity and prostaglandin release from alveolar macrophages exposed to asbestos. (1980) (33)
- Consequences of alteration in capillary permeability. (1996) (33)
- The kinin system mediates hyperalgesia through the inducible bradykinin B1 receptor subtype: evidence in various experimental animal models of type 1 and type 2 diabetic neuropathy (2006) (32)
- Cloning of the guinea pig 5-lipoxygenase gene and nucleotide sequence of its promoter. (1992) (32)
- Guinea pig alveolar eosinophils and macrophages produce leukotriene B4 but no peptido-leukotriene. (1990) (32)
- Relaxant effects of pituitary adenylate cyclase activating polypeptide (PACAP) on epithelium-intact and -denuded guinea-pig trachea: a comparison with vasoactive intestinal peptide (VIP) (1995) (31)
- Antiaggregatory and hypotensive effects of endothelin-1 in beagle dogs: role for prostacyclin. (1991) (31)
- Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs. (2005) (30)
- Plasma extravasation induced by neurokinins in conscious rats: receptor characterization with agonists and antagonists. (1993) (30)
- Inhibition of Type 1 Diabetic Hyperalgesia in Streptozotocin-Induced Wistar versus Spontaneous Gene-Prone BB/Worchester Rats: Efficacy of a Selective Bradykinin B1 Receptor Antagonist (2005) (30)
- Inhibition of Ehrlich ascites tumor in vivo by PAF-antagonists. (1990) (29)
- Leukotriene B4 receptors on guinea pig alveolar eosinophils. (1991) (29)
- Hemodynamic effects of PAF-acether on the dog kidney. (1987) (29)
- Potent thromboxane-mediated in vitro bronchoconstrictor effect of endothelin in the guinea-pig. (1990) (28)
- Hepcidin increases intracellular Ca2+ of osteoblast hFOB1.19 through L-type Ca2+ channels (2011) (28)
- C‐reactive protein inhibits intracellular calcium mobilization and superoxide production by guinea pig alveolar macrophages (1992) (28)
- Human urotensin-II enhances plasma extravasation in specific vascular districts in Wistar rats. (2004) (28)
- Release of prostaglandins from the rabbit renal medulla. (1974) (27)
- Structural requirement for the action of leukotriene B4 on the guinea-pig lung:importance of double bond geometry in the 6, 8, 10-triene unit. (1981) (27)
- Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6‐keto‐PGF1α, thromboxane B2 and histamine on selected smooth muscle preparations (1981) (27)
- Modulation of allergic and immune complex-induced lung inflammation by bradykinin receptor antagonists (2004) (26)
- [Pharmacology of the leukotrienes]. (1984) (25)
- Implication of the bradykinin receptors in antigen‐induced pulmonary inflammation in mice (2003) (25)
- Selective Inflammatory Response Induced by Intratracheal and Intravenous Administration of Poly-L-Arginine in Guinea Pig Lungs (1999) (24)
- Specificity of receptors for leukotrienes A4, B4, C4, D4, E4 and histamine on the guinea-pig lung parenchyma. Effect of FPL-55712 and desensitization of the myotropic activity. (1983) (24)
- Early effects of low-doses exposure to asbestos on local cellular immune responses in the lung. (1981) (24)
- Effects of eicosanoids, neuromediators and bioactive peptides on murine airways. (2000) (23)
- Blockade of early and late retinal biochemical alterations associated with diabetes development by the selective bradykinin B1 receptor antagonist R-954 (2012) (23)
- Role of R‐type calcium channels in the response of the perfused arterial and venous mesenteric vasculature of the rat to platelet‐activating factor (1994) (23)
- Endothelin-induced constriction of guinea pig airways: role of platelet-activating factor. (1990) (23)
- Renal permeability alteration precedes hypertension and involves bradykinin in the spontaneously hypertensive rat. (1992) (23)
- Involvement of LTD4in allergic pulmonary inflammation in mice: modulation by cysLT1antagonist MK-571 (2000) (23)
- Effects of Tranexamic Acid and Aprotinin, Two Antifibrinolytic Drugs, on PAF-induced Plasma Extravasation in Unanesthetized Rats (2000) (22)
- Asbestos related changes in pulmonary and systemic immune responses--early enhancement followed by inhibition. (1982) (21)
- Carbamylcholine‐ and 5‐hydroxytryptamine‐induced contraction in rat isolated airways: inhibition by calcitonin gene‐related peptide (1990) (21)
- Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats. (2005) (21)
- Role of cyclooxygenase products in the lung action of leukotrienes A4, B4, C4, D4 and E4. (1985) (21)
- Studies on the mechanism of PAF-induced vasopermeability in rat lungs. (1995) (21)
- Changes in plasma levels of vasopressin and renin in response to haemorrhage in dogs (1973) (21)
- Role of endothelial cells in cardiovascular function. (1994) (20)
- Removal of guinea pig bronchial and tracheal epithelium potentiates the contractions to leukotrienes and histamine. (1990) (20)
- Comparative activity of natural mono-, di- and tri-hydroxy derivatives of arachidonic acid on guinea-pig lungs: myotropic effect and stimulation of cyclooxygenase activity. (1982) (19)
- Preclinical pharmacology, metabolic stability, pharmacokinetics and toxicology of the peptidic kinin B1 receptor antagonist R-954 (2014) (19)
- Bradykinin B1 antagonism inhibits oxidative stress and restores Na+K+ ATPase activity in diabetic rat peripheral nervous system (2013) (19)
- Increased plasma levels of endothelin during anaphylactic shock in the guinea-pig. (1993) (19)
- Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists. (1986) (19)
- Inhibition by rapamycin of leukocyte migration and bronchial hyperreactivity induced by injection of Sephadex beads to guinea‐pigs (1993) (18)
- Paf induces rat plasma extravasation and releases eicosanoids during anaphylaxis (1991) (18)
- Therapeutic Potential of RNA Interference Against Cellular Targets of HIV Infection (2007) (18)
- Studies on the biosynthesis of leukotrienes in guinea pig lung in vitro by use of high-performance liquid chromatography. (1986) (18)
- Antidiabetic efficacy of bradykinin antagonist R-954 on glucose tolerance test in diabetic type 1 mice (2010) (17)
- Effect of indapamide on phosphate metabolism and vascular reactivity. (1988) (17)
- Bradykinin B1 receptor antagonist R954 inhibits eosinophil activation/proliferation/migration and increases TGF-β and VEGF in a murine model of asthma (2010) (17)
- Effect of PAF on rat lung vascular permeability: role of platelets and polymorphonuclear leucocytes (1994) (17)
- Characterization of leukotriene B4 binding sites on guinea pig lung macrophages. (1988) (17)
- Leukotriene transformation by guinea-pig lungs. (1983) (17)
- Prostaglandins, leukotrienes and PAF selectively modulate lymphocyte subset and eosinophil infiltration into the airways in a murine model of asthma. (2007) (16)
- Repression of the 5-lipoxygenase gene by c-myb overexpression in differentiated HL-60 cells. (1997) (16)
- Stimulation by angiotensin II of the release of vasopressin from incubated rat neurohypophyses—possible involvement of cyclic AMP (1975) (16)
- Paf‐induced release of spasmogens from guinea‐pig lungs (1989) (16)
- Prostaglandin E2 increases cyclic AMP and inhibits endothelin‐1 production/secretion by guinea‐pig tracheal epithelial cells through EP4 receptors (2001) (16)
- In vivo effects of leukotriene B4, C4 and D4. Evidence that changes in blood pressure are mediated by prostaglandins. (1981) (16)
- Effects of angiotensin-converting enzyme inhibitor plus irbesartan on maximal and submaximal exercise capacity and neurohumoral activation in patients with congestive heart failure. (2005) (16)
- Mechanism of action of leukotriene D4 on guinea pig tracheal smooth muscle cells: roles of Ca++ influx and intracellular Ca++ release. (1997) (16)
- Lipid peroxidation in rat alveolar macrophages exposed to chrysotile fibres. (1988) (16)
- Leukotriene receptors in HL-60 cells differentiated into eosinophils, monocytes and neutrophils. (1996) (16)
- Roles of endothelins and their receptors in immune complex-induced/polymorphonuclear-mediated lung injury (reversed passive arthus reaction) in CD-1 mice. (1998) (16)
- Role of the neutral endopeptidase 24.11 in the conversion of big endothelins in guinea‐pig lung parenchyma (1996) (16)
- Hemodynamic effects of PAF-acether. (1986) (16)
- Guinea pig Clara cells secrete endothelin 1 through a phosphoramidon-sensitive pathway. (1996) (16)
- Contribution of B2 receptors for bradykinin in Arthus reaction‐induced plasma extravasation in wild‐type or B2 transgenic knockout mice (2000) (15)
- Modulation of endothelin production and metabolism in guinea-pig tracheal epithelial cells by peptidase inhibitors. (1997) (15)
- Metabolism of leukotrienes by adult and fetal human lungs. (1985) (15)
- THE LEUKOTRIENES: A MAJOR STEP IN THE UNDERSTANDING OF IMMEDIATE HYPERSENSITIVITY REACTIONS (1981) (15)
- Adenosine induces cyclic‐AMP formation and inhibits endothelin‐1 production/secretion in guinea‐pig tracheal epithelial cells through A2B adenosine receptors (2000) (15)
- Induction of lung eosinophilia and neutrophilia in guinea pigs following injection of Sephadex beads (1993) (15)
- Involvement of eicosanoids and PAF in immune-complex alveolitis. (1989) (15)
- A rat model presenting eosinophilia in the airways, lung eosinophil activation, and pulmonary hyperreactivity. (1999) (15)
- Involvement of LTD(4)in allergic pulmonary inflammation in mice: modulation by cysLT(1)antagonist MK-571. (2000) (15)
- Biological and molecular analyses of structurally reduced analogues of endothelin-1. (1996) (15)
- The rat isolated colon as a specific assay organ for angiotensin (1972) (15)
- Atrial Natriuretic Factor Immunoreactivity in Human Fetal Lung Tissue and Perfusates (1988) (15)
- Consequences of alteration in capillary permeability (1996) (14)
- CRISPR/Cas: A Faster and More Efficient Gene Editing System. (2015) (14)
- The bradykinin B1 receptor antagonist R-954 inhibits Ehrlich tumor growth in rodents (2011) (14)
- [Functional duality of kinin receptors in pathophysiology]. (2003) (14)
- In Vivo Evaluation of Cerebral Transplantation of Resovist-Labeled Bone Marrow Stromal Cells in Parkinson’s Disease Rats Using Magnetic Resonance Imaging (2011) (14)
- Release of prostaglandins and rabbit aorta contracting substance (RCS) from guinea-pig lung by slow reacting substance of anaphylaxis (SRS-A) [proceedings]. (1977) (13)
- Pulmonary surfactant lipids inhibit prostanoid production of guinea pig alveolar macrophages (1994) (13)
- Platelet activating factor antagonism with BN52021 protects the kidney against acute ischemic injury. (1988) (13)
- Endothelin-1 does not affect human platelet aggregation in whole blood and platelet rich plasma. (1990) (12)
- Biochemical components of bronchoalveolar lavage in early experimental asbestosis of the sheep: phospholipase A2 activity, prostaglandin E2 and proteins. (1983) (12)
- The role of kallikrein-kinin and renin-angiotensin systems in COVID-19 infection (2020) (12)
- Leukotrienes: One step in our understanding of asthma. (2019) (12)
- Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin. (1989) (12)
- Release of prostaglandins and thromboxanes by guinea pig isolated type II pneumocytes. (1990) (12)
- An adherent cell perifusion technique to study the overall and sequential response of rat alveolar macrophages to toxic substances. (1983) (12)
- Interaction between the release of SRS-A and of prostaglandins [proceedings]. (1976) (12)
- Increase in cyclic AMP levels and vasopressin release in response to angiotensin I in neurohypophyses: Blockade following inhibition of the converting enzyme (1975) (11)
- Potentiating effects of leukotriene B4 and prostaglandin E2 on urinary sodium excretion by the dog kidney. (1985) (11)
- Bradykinin Stimulates MMP-2 Production in Guinea Pig Tracheal Smooth Muscle Cells (2003) (11)
- Effect of Zileuton (A-64077) on the 5-lipoxygenase activity of human whole bloodex vivo (1991) (11)
- Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions. (1987) (11)
- A role for Na+/H+ exchange in contraction of guinea pig airways by endothelin-1 in vitro. (1991) (11)
- Prostaglandin E(2) increases cyclic AMP and inhibits endothelin-1 production/secretion by guinea-pig tracheal epithelial cells through EP(4) receptors. (2001) (11)
- Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells. (1998) (10)
- Pharmacological characterization of Sephadex-induced oedema in rat paws: predominant role of serotonin and platelet-activating factor. (1996) (10)
- Triple VPI CGS 35601 Reduces High Blood Pressure in Low-Renin, High-Salt Dahl Salt-Sensitive Rats (2006) (10)
- Endothelins Mediate Neutrophil Activation, ProMMP-9 Release and Endothelial Cell Detachment (2007) (10)
- Comparative effects of platelet activating factor, leukotriene D4 and histamine on guinea pig trachea, bronchus and lung parenchyma. (1987) (10)
- Inhibitory effects of a novel platelet activating factor (PAF) antagonist (BN 52021) on antigen-induced prostaglandin and thromboxane formation by the guinea pig lung. (1986) (10)
- Inhibition of platelet-activating factor induced renal hemodynamic and tubular dysfunctions with L-655,240, a new thromboxane-prostaglandin endoperoxide antagonist. (1989) (10)
- Pathways for the bradykinin B1 receptor-mediated diabetic hyperalgesia in mice (2004) (10)
- Correlation between the myotropic activity of leukotriene A4 on guinea-pig lung, trachea and ileum and its biotransformation in situ. (1985) (9)
- Response of perifused alveolar macrophages to glass fibers: effect of exposure duration and fiber length. (1986) (9)
- Leukotriene B4 binding sites in guinea-pig alveolar macrophages. (1990) (9)
- Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. (2003) (9)
- Dexamethasone and Phosphoramidon Inhibit Endothelin Release by Cultured Nonciliated Bronchiolar Epithelial (Clara) Cells (1995) (9)
- Tumor necrosis factor primes the effects of platelet-activating factor on rat vascular permeability. (1990) (9)
- The First Preclinical Pharmacotoxicological Safety Assessment of CGS 35601, a Triple Vasopeptidase Inhibitor, in Chronically Instrumented, Conscious, and Unrestrained Spontaneously Hypertensive Rats (2006) (9)
- Aprotinin, an antifibrinolytic drug, attenuates bradykinin-induced permeability in conscious rats via platelets and neutrophils. (1997) (9)
- Acute and chronic diuretic treatment selectively affects vascular permeability in the unanesthetized normal rat. (1994) (9)
- Rapamycin inhibits airway leukocyte infiltration and hyperreactivity in guinea pigs (2005) (9)
- The Hemodynamic and Metabolic Profiles of Zucker Diabetic Fatty Rats Treated with a Single Molecule Triple Vasopeptidase Inhibitor, CGS 35601 (2006) (9)
- Guinea Pig Lung Eosinophil: Purification and Prostaglandin Production (1989) (9)
- Natural killer and lectin-dependent cytotoxic activities of kurloff cells: Target cell selectivity, conjugate formation, and Ca++ dependency (1996) (9)
- Structure-activity relationships of ET-1 and selected analogues in the isolated guinea pig trachea: evidence for the existence of different ETB receptor subtypes. (1993) (8)
- Leukotrienes: A new approach to the biochemistry of hypersensitivity (1982) (8)
- Cell-cell interactions between platelets, macrophages, eosinophils and natural killer cells in thromboxane A2 biosynthesis. (1993) (8)
- Effects of dexamethasone on the basal and cytokine-stimulated release of endothelin-1 from guinea-pig cultured tracheal epithelial cells. (1997) (8)
- Activation of peritoneal macrophages during the evolution of type 1 diabetes (insulitis) in streptozotocin-treated mice (2010) (8)
- Profiling biochemical and hemodynamic markers using chronically instrumented, conscious and unrestrained rats undergoing severe, acute controlled hemorrhagic hypovolemic shock as an integrated in-vivo model system to assess new blood substitutes. (2005) (8)
- Effects of dexamethasone on the basal and cytokine-stimulated release of endothelin-1 from guinea-pig cultured tracheal epithelial cells (1997) (7)
- Metabolism of arachidonic acid by guinea pig Clara cells. (1991) (7)
- Phosphoramidon and thiorphan suppress the generation of endothelin (ET) from exogenous big-endothelin by guinea pig Clara cells (1997) (7)
- Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips. (1988) (7)
- Perifused alveolar macrophages. A technique to study the effects of toxicants on prostaglandin release (1982) (7)
- Changes in chromatin conformation regulate the 5-lipoxygenase gene expression during differentiation of HL60 cells. (1996) (7)
- Early Bronchial Hyperresponsiveness Following Injection of Sephadex Beads in the Guinea Pig: Involvement of Platelet Activating Factor and Thromboxane A2 (1999) (7)
- Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice. (2007) (7)
- Comparative activity of leukotriene D4, 5,6-dihydroxy-eicosatetraenoic acid and lipoxin A on guinea pig lung parenchyma and ileum smooth muscle. (1988) (7)
- Developmental changes in synthesis of and responsiveness to prostaglandins I2 and E2 in hypoxic lamb lungs. (1998) (7)
- Murine hypersensitivity pneumonitis: evidences for the role of eicosanoids and platelet activating factor. (1993) (7)
- Oxidative stress in the optic nerve and cortical visual area of steptozotocin-induced diabetic Wistar rats: Blockade with a selective bradykinin B1 receptor antagonist (2017) (7)
- Downregulation of Ferroportin 1 Expression in hFOB1.19 Osteoblasts by Hepcidin (2012) (6)
- Structure-activity relationship of analogues of endothelin-1: dissociation of hypotensive and pressor actions. (1992) (6)
- Measurements of prostanoids, leukotrienes, and isoprostanes by enzyme immunoassays. (1998) (6)
- Structural requirements for angiotensin analogues to accumulate cyclic AMP and release vasopressin from the incubated rat neurohypophysis (1975) (6)
- Development of a radioimmunoassay data analysis pack (RIADAP) in level II basic for microcomputers. (1983) (6)
- Profile of Endothelin Isopeptides and Markers of Oxidative Stress Alongside the Onset of Streptozotocin-Type I Diabetes in Rats (2004) (6)
- Diuretic and natriuretic properties of prestegane B, a mammalian lignan. (1987) (6)
- Eosinophils and neutrophils modify arachidonic acid-induced relaxation of guinea-pig trachea. (1996) (6)
- Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF. (1987) (6)
- Guinea pig kurloff (NK-like) cells mediate TNF-dependent cytotoxic activity: Analogy with NC effector cells (1996) (6)
- Endothelial and smooth muscle pharmacology of pre- and post-capillary microcirculation: correlation with plasma extravasation. (1996) (6)
- Gossypol: a potent inhibitor of PAF‐acether‐ and leukotriene‐induced contractions of guinea‐pig lung parenchyma strips (1987) (6)
- Further studies on the mechanism of action of leukotrienes and histamine on guinea pig lung parenchyma. Role of calcium, phospholipase and methyltransferase. (1986) (6)
- Molecular diagnosis of HIV and relevant novel technologies in mutation analysis. (2008) (6)
- Interaction between prostaglandin E2 and leukotriene D4 on the excretion of electrolytes by the dog kidney in vivo. (1987) (6)
- Role of Airway Eosinophilia and Eosinophil Activation in Sephadex-induced Inflammation (2004) (6)
- Double dioxygenation of arachidonic acid in leukocytes by lipoxygenases. (1982) (6)
- Specific leukotriene D4 receptors on guinea-pig alveolar macrophages. (1988) (5)
- Specific binding sites for leukotriene B4 in guinea pig brain membranes. (1991) (5)
- Leukotriene C4 receptors on guinea pig tracheocytes. (1995) (5)
- Inhibition of Prostaglandin G/H Synthase Unveils a Potent Effect of Platelet Activating Factor on the Permeability of Bovine Aortic Endothelial Cells to Albumin (2002) (5)
- Purification of natural killer-like Kurloff cells and arachidonic acid metabolism. (1991) (5)
- Release of mediators from free bronchoalveolar cells: effect of ionophore A23187 and antigen challenge. (1980) (5)
- A Law of Mutation: Power Decay of Small Insertions and Small Deletions Associated with Human Diseases (2010) (5)
- Angiotensin converting enzyme inhibition and autoregulation of glomerular filtration. (1988) (5)
- Effect of tumor necrosis factor receptor binding protein on cell infiltration induced by lipopolysaccharide and sephadex beads in guinea pig lung (1995) (5)
- Highly purified guinea pig type II pneumocytes have the leukotriene A4 hydrolase but do not express 5-lipoxygenase activity. (1994) (5)
- Characterization of the Endothelin‐Converting Enzyme in Guinea Pig Upper Bronchus (1995) (5)
- Cellular and humoral components of bronchoalveolar lavage in the sheep (2007) (5)
- Effects of a selective neutral endopeptidase and a nonselective neutral endopeptidase/endothelin-converting enzyme inhibitor on lipopolysaccharide-induced endotoxaemia in anaesthetized Sprague-Dawley rats. (2000) (4)
- [Oxygen and the superoxide anion. Modulation of NADPH oxidase?]. (2001) (4)
- Relaxation by dexamethasone of isolated guinea-pig airways precontracted with endothelin-1. (1993) (4)
- Integrated in vivo pharmacology using an instrumented, unrestrained and conscious rat platform: application to rat models of diabetes. (2006) (4)
- Increased permeability of bovine aortic endothelial cell monolayers in response to a thromboxane A2-mimetic. (1995) (4)
- Vascular-derived myocardial contractile factor: positive myocardial inotropic substance released from medial layer of the canine aorta. (1996) (4)
- Triple Vasopeptidase Inhibition of Angiotensinconverting Enzyme/Neutral Endopeptidase/Endothelinconverting Enzyme Activities on the Hemodynamic Profile of Chronically Instrumented Unrestrained Conscious Spontaneously Hypertensive Rats (2004) (4)
- Secretion of thromboxane B2 and prostaglandin E2 by guinea-pig lung cells isolated by centrifugal elutriation and by macrophages obtained by bronchoalveolar lavage. (1989) (4)
- Synthesis of eicosanoids by isolated guinea pig tracheocytes. (1991) (4)
- Release of eicosanoids in rat peritoneal cavity stimulated with platelet-activating factor (PAF). Effect of the PAF-antagonist BN-52021. (1989) (4)
- Technology evaluation: ISIS-3521. (1999) (4)
- Guinea pig bronchus as a model for icosanoid studies (1987) (4)
- Effect of asbestos on the metabolism of vasoactive substances in isolated perfused guinea pig lungs. (1983) (4)
- Neutral endopeptidase degrades endothelins in guinea pig tracheal epithelial cells (1997) (4)
- Electrophysiological consequences of leukotrienes applied on isolated rat retina. (1985) (4)
- Adenosine-induced inhibition of basal endothelin-1 production from guinea-pig tracheal epithelial cells: a mechanism involving the release of cAMP. (1998) (4)
- Characterization of an angiotensin II‐fluorescamine derivative (1975) (3)
- Measurements of arachidonic acid metabolites derived from the lipoxygenase pathways by high-pressure liquid chromatography. (1998) (3)
- Measurement of β-glucuronidase in effluent of perifused alveolar macrophages challenged with chemically modified chrysotile asbestos (1984) (3)
- Endothelin derivatives showing potent effects in the guinea pig trachea (1993) (3)
- Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage (2022) (3)
- A new strategy for next generation sequencing: merging the Sanger's method and the sequencing by synthesis through replacing extension. (2011) (3)
- Role of icosanoids in alveolar macrophage phagocytosis and aggregation. (1986) (3)
- Further studies on the inactivation of slow-reacting substance of anaphylaxis by lipoxidase. (1980) (3)
- Platelet activating factor modulates peptidoleukotriene effects on the permeability of bovine aortic endothelial cell to albumin (2005) (3)
- Erratum to “Role of bradykinin B1 receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice” [Eur. J. Pharmacol. 457 (2002) 115–124] (2003) (3)
- Evidence for the inactivation of neurotensin by guinea pig lungs (1981) (3)
- Partial inhibition of prostaglandin‐induced contraction of the rat colon by analogues of angiotensin II (1980) (3)
- Association of Endothelin with Lung Hemorrhage Induced by Immune Complexes in Rats (2004) (2)
- Release of renomedullary prostaglandins in normal and hypertensive rats (1974) (2)
- Primerless Amplification for Circulating Tumor DNA Assays. (2019) (2)
- Structure‐Activity Studies of the C‐Terminal Segment of Structurally Reduced Analogues of ET‐1 (1995) (2)
- Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis (1984) (2)
- Pharmacology of the leukotrienes. (1985) (2)
- Effect of platelet activating factor of renal hemodynamics and sodium excretion (1985) (2)
- Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells. (1988) (2)
- Reduction of Sephadex-induced lung inflammation and bronchial hyperreactivity by rapamycin. (1993) (2)
- An Excess of G over C Nucleotides in Mutagenesis of Human Genetic Diseases (2011) (2)
- Kinetics of eosinophilia and eosinophil activation in the development of non-allergic bronchial hyperresponsiveness in guinea pigs injected with Sephadex beads (1996) (2)
- Modulation of the Eicosanoid Metabolism by Diuretics and Related Drugs (1983) (2)
- Inhibitory Effect of Bradykinin B1 Receptor Antagonist R-954 on Breast Xenograft Tumors in BALB/c Mice (2015) (2)
- Inactivation of prostaglandin E2 by rabbit lung homogenates (1974) (2)
- Extraction and measurements of prostanoids and leukotrienes by radioimmunoassays. (1998) (2)
- Comparison of rat, mouse, guinea-pig and human slow reacting substance of anaphylaxis (SRS-A) (1979) (2)
- Interactions between leukotrienes and other eicosanoids. (1985) (2)
- Sodium-phosphate cotransport and vascular reactivity. (1991) (2)
- Inhibitory effect of econazole on the release of thromboxanes (1991) (2)
- [Leukotrienes and inflammation]. (1985) (2)
- Guinea pig lung cells (1989) (2)
- Evidence for the activation of the kallikrein-kinin system in experimental asbestosis. (1984) (2)
- Relationship between leukotriene A4 metabolism and biological activity (1984) (1)
- Specific increase of microvascular permeability in lower airways of guinea pigs injected with Sephadex beads (1995) (1)
- Further evidence on the structure of slow reacting substance of anaphylaxis (SRS-A) (1979) (1)
- Leukotrienes B4 and D4 and the renal transport of ions (1984) (1)
- Stimulation of release of prostaglandins and thromboxanes from isolated guinea pig lung cells by Bradykinin, f-Met-Leu-Phe, phorbol myristate, ionophore a23187, and leukotrienes (1988) (1)
- 1012-129 Dual angiotensin-II suppression with angiotensin-converting enzyme inhibitor and irbesartan improves submaximal exercise time without changes in exercise-induced neurohumoral response in patients with congestive heart failure (2004) (1)
- Release of Leukotrienes B4 and D4 by the Anaphylactic Guinea Pig Lung in Vitro (1985) (1)
- Metabolism of arachidonic acid by isolated lung cells and transcellular biosynthesis of thromboxanes. (1991) (1)
- The mechanism of action of leukotrienes A4, C4 and D4 on human lung parenchymain vitro (2007) (1)
- Transforming viral sequences to A (H1N1) flu diagnosis: the current status and future prospects of rtPCR based assays. (2010) (1)
- Drug-induced alteration of endothelial permeability in the rat aorta. Potential consequences on the vessel wall. (1996) (1)
- Characterization of leukotrienes receptors on guinea-pig lung parenchyma (1982) (1)
- Lipid Mediators in Lung Anaphylaxis: Kinetics of Their Release and Modulation by Selected Drugs (1987) (1)
- Effect of PAF on selected smooth muscle preparations. (1989) (1)
- Effects of indomethacin on prostaglandin E2 and thromboxane B2 contents of tracheal lavage fluids in premature infants (1991) (1)
- Tertatolol increases glomerular filtration and urinary sodium in anesthetized rats. (1989) (1)
- [Contribution of the vascular interstitial matrix to induced contraction by angiotensin II. In vitro studies on the rabbit aorta, mesenteric artery and vein]. (1996) (1)
- 527 Natural cytotoxic cell activity enhanced by leukotriene B4 (1983) (1)
- Converting enzyme activity of free airway cells (1986) (1)
- Mechanism of action of leukotrienes on the guinea pig bronchus. (1988) (1)
- Relationship between the development of bronchial hyperresponsiveness and the airway eosinophilia in guinea pigs following injection with Sephadex beads (1995) (1)
- [Effect of hypercholesterolemia on vascular reactivity: repercussions on renal hemodynamics in the rabbit]. (1994) (1)
- Lack of correlation between serum angiotensin-converting enzyme levels and asbestosis in man, sheep and guinea-pig (2007) (1)
- Metabolism of arachidonic acid by Foà-Kurloff cells from guinea pig lungs and spleen. (1991) (0)
- Pathophysiology of Renal Failure in Shock: Role of Lipid Mediators (1987) (0)
- Granulocyte recruitment in guinea pig lungs following the administration of MBP-like cationic protein (1995) (0)
- Endothelin and bradykinin antagonism improves nociceptive tolerance and protects carilage joint degardation in osteoarthritis (2012) (0)
- DesArg9BK increases the permeability of bovine aortic endothelial monolayer to iodinated albumin (1997) (0)
- Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits. (1991) (0)
- Understanding of and possible strategies to avian influenza outbreak. (2014) (0)
- Effect of Autophagy Mediated by Tumor Associated Macrophage on Invasiveness of the Tumor (2015) (0)
- Leukotriene receptors. (1989) (0)
- Early biochemical reactions in the lung of sheep exposed to asbestos: Evidence for cyclic AMP accumulation in bronchoalveolar lavage fluids (2007) (0)
- Downregulation of Ferroportin 1 Expression in hFOB1.19 Osteoblasts by Hepcidin (2012) (0)
- Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein. (2001) (0)
- A Sensitive Assay Enriched with Blue/White Screening to Empower Sequencing Analysis for G > A Hotspot Mutation in Codon 13 of KRAS Gene (2017) (0)
- New Gene Therapy Strategies for the Deletion of Exon 44 of Dystrophin Gene Based on Gene Editing by TALENs (2013) (0)
- PAF antagonism in renal ischemia (1988) (0)
- Inhibition of airway hyperreactivity, edema, and lung cell infiltration by compound U-83836E in sensitized guinea pigs. (1998) (0)
- Effect ofPAFon ratlungvascular permeability: role of platelets andpolymorphonuclear leucocytes (1994) (0)
- Roleoftheneutral endopeptidase 24.11intheconversion ofbig endothelins inguinea-piglungparenchyma (1996) (0)
- The Updated Concept of Genome and Its Implications in Biotechnological Research and Molecular Diagnostics (2009) (0)
- Healthier Life: A Goal of Gene and Gene Editing (2015) (0)
- Cell-derived Mediators in Relation to Asbestos-Related Tissue Injury and Fibrogenesis (1985) (0)
- Effect of a BK Receptor Antagonist (R‐954) in Experimental Endometriosis (2019) (0)
- Pathological Implications of Hepatitis B Viral DNA Integration Into Host Cells (2015) (0)
- Hemodynamic responses and neurohormonal activation in “responders” vs. “non-responders” to triple neurohormonal blockade in congestive heart failure (2004) (0)
- Effect of tnf binding protein on antigen induced bronchial hyperreactivity and cell infiltration in rat lungs (1995) (0)
- Inhibition of Basal and Stimulated Release of Endothelin-1 from Guinea Pig Tracheal Epithelial Cells in Culture by Beta 2-adrenoceptor Agonists and Cyclic AMP Enhancers (2007) (0)
- Activation of blood complement in guinea pigs receiving an intravenous injection of Sephadex beads (1995) (0)
- Early Cancer Diagnosis with ctDNA as a Liquid Biopsy Target (2015) (0)
- Induction byendothelin- 1ofepithelium-depen dent relaxation ofguinea-pig trachea invitro: role fornitric oxide (1993) (0)
- Subject Index Vol. 109, 1996 (1996) (0)
- Platelet-Activating Factor in Renal Pathophysiology: The Effects of PAF Antagonists (1988) (0)
- Neurohypophyseal effects of angiotensin: further studies (1976) (0)
- 529 COULD SPECIFIC PEPTIDE ANTAGONISTS OF ENDOTHELIN RECEPTOR TYPE A AND BRADYKININ RECEPTOR 1 ACT AS POTENTIAL TREATMENTS FOR OSTEOARTHRITIS (2009) (0)
- Evidence for the activation of blood complement in Sephadex beads-induced lung inflammation in guinea pigs (1999) (0)
- 27 Hypercholesterolaemia and vascular reactivity: impact on renal haemodynamics in the rabbit (1994) (0)
- [Leucotriens: conclusion of 40 years' research on mediators of anaphylaxis]. (1980) (0)
- Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy (2023) (0)
- SARS-CoV-2 Infected Cases with Untraceable Epidemic Origin: Its Values, Identification and TCM Treatment in Preventing Recurrence (2020) (0)
- Metabolism of Arachidonic Acid by Purified Lung Epithelial Cells (1991) (0)
- Disorders of Vascular Permeability: Pathophysiological and Clinical Implications (1993) (0)
- Effect of increasing doses of a selective bradykinin B1 receptor antagonist in streptozotocin -type I diabetic chronically instrumented rats (2004) (0)
- The mechanism of aspirin (2018) (0)
- [Hypothesis on the inactivation mechanism of slow reacting substance of anaphylaxis (SRS-A)]. (1980) (0)
- Special Issue on Peptide Receptors: Focus on Neuropeptides and Kinins Bradykinin B 1 receptor antagonist R954 inhibits eosinophil activation/proliferation/migration and increases TGF-b and VEGF in a murine model of asthma (2010) (0)
- [Utilization of cascade superfusion technic for the determination of renin in the plasma]. (1972) (0)
- Effects of tranexamic acid and aprotinin on PAF-induced vascular permeability in normal, thrombocytopenic or neutropenic rats (1997) (0)
- Different Mortality Rates of Chinese Residents to SARS and H1N1 Flu: Their Potential Value in Viral Virulence Estimation (2012) (0)
- Contents, Vol. 109, 1996 (1996) (0)
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What Schools Are Affiliated With Pierre Sirois?
Pierre Sirois is affiliated with the following schools: