Pak Sham
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Computer Science
Pak Sham's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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Why Is Pak Sham Influential?
(Suggest an Edit or Addition)According to Wikipedia, Pak Chung Sham is a psychiatric geneticist. He holds the Suen Chi-Sun Professorship in Clinical Science at the University of Hong Kong, where he is also the Chair Professor in Psychiatric Genomics, Director of the Centre for Genomic Sciences, and Director of Academic Developments in the Department of Psychiatry. He was a Professor of Psychiatric and Statistical Genetics at the Institute of Psychiatry, Psychology and Neuroscience from 2000 to 2006. He first joined the faculty of the University of Hong Kong as a visiting professor in 2004, where he became Chair Professor in Psychiatric Genomics in 2006. He is the editor-in-chief of the peer-reviewed journal Human Heredity.
Pak Sham's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- PLINK: a tool set for whole-genome association and population-based linkage analyses. (2007) (25309)
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- A second generation human haplotype map of over 3.1 million SNPs (2007) (4567)
- Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits (2003) (2143)
- The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. (2003) (1121)
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (2012) (1045)
- The support of human genetic evidence for approved drug indications (2015) (930)
- Stress and Psychological Distress among SARS Survivors 1 Year after the Outbreak (2007) (910)
- Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. (1999) (806)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals (2009) (723)
- Statistical methods of estimation and inference for functional MR image analysis (1996) (715)
- Analytic approaches to twin data using structural equation models (2002) (690)
- Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. (2005) (652)
- The future of association studies: gene-based analysis and replication. (2004) (632)
- Immediate and Sustained Psychological Impact of an Emerging Infectious Disease Outbreak on Health Care Workers (2007) (618)
- Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia (2002) (602)
- Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). (2006) (591)
- A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 (2008) (578)
- DNA Pooling: a tool for large-scale association studies (2002) (560)
- Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets (2011) (554)
- Statistics in human genetics (1997) (553)
- A randomized controlled study of cognitive therapy for relapse prevention for bipolar affective disorder: outcome of the first year. (2003) (536)
- Meta-analysis of the P300 and P50 waveforms in schizophrenia (2004) (536)
- Statistical power and significance testing in large-scale genetic studies (2014) (518)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder (2004) (488)
- A twin study of genetic relationships between psychotic symptoms. (2002) (457)
- Model-Free Analysis and Permutation Tests for Allelic Associations (1999) (443)
- The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study (2019) (401)
- Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. (2004) (387)
- Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus (2010) (385)
- Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006. (2009) (371)
- A note on the calculation of empirical P values from Monte Carlo procedures. (2002) (361)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- GATES: a rapid and powerful gene-based association test using extended Simes procedure. (2011) (359)
- Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. (2002) (354)
- Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict the Development of the Metabolic Syndrome: A 5-Year Prospective Study (2007) (338)
- Comparative genetic architectures of schizophrenia in East Asian and European populations (2018) (329)
- Relapse prevention in patients with bipolar disorder: cognitive therapy outcome after 2 years. (2005) (326)
- Powerful regression-based quantitative-trait linkage analysis of general pedigrees. (2002) (295)
- Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases (2011) (294)
- Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. (2000) (279)
- International Cooperation to Enable the Diagnosis of All Rare Genetic Diseases (2017) (275)
- Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration (2008) (274)
- Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study (2010) (267)
- Pre-morbid characteristics and co-morbidity of methamphetamine users with and without psychosis (2003) (258)
- Serum Adipocyte Fatty Acid–Binding Protein as a New Biomarker Predicting the Development of Type 2 Diabetes (2007) (257)
- Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response (1998) (254)
- A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases (2012) (253)
- Prenatal malnutrition and adult schizophrenia: further evidence from the 1959-1961 Chinese famine. (2009) (225)
- Low copy number of the salivary amylase gene predisposes to obesity (2014) (224)
- Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study (2005) (222)
- Evidence for association between polymorphisms in the promoter and coding regions of the 5-HT2A receptor gene and response to clozapine (1998) (216)
- Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives. (2006) (215)
- Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies (2018) (213)
- Polygenic scores via penalized regression on summary statistics (2017) (212)
- Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. (2014) (210)
- Genetic Contributions to Regional Variability in Human Brain Structure: Methods and Preliminary Results (2002) (210)
- Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples (2008) (208)
- A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25 (2010) (207)
- Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder (2005) (199)
- GWASdb: a database for human genetic variants identified by genome-wide association studies (2011) (194)
- Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. (2004) (193)
- Schizophrenia Following Pre-natal Exposure to Influenza Epidemics Between 1939 and 1960 (1992) (193)
- Cognitive Therapy for Bipolar Illness—A Pilot Study of Relapse Prevention (2000) (192)
- Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects (2007) (192)
- Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians (2011) (191)
- Heritability and Reliability of P300, P50 and Duration Mismatch Negativity (2006) (185)
- microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma (2010) (184)
- The determinants of parenting: an epidemiological, multi-informant, retrospective study (1997) (184)
- A note on the application of the transmission disequilibrium test when a parent is missing. (1995) (184)
- Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. (2013) (184)
- Association between clozapine response and allelic variation in the 5-HT2C receptor gene (1995) (183)
- A meta‐analysis of association studies between the 10‐repeat allele of a VNTR polymorphism in the 3′‐UTR of dopamine transporter gene and attention deficit hyperactivity disorder (2007) (183)
- Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation (2010) (179)
- Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. (2010) (178)
- Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals (2019) (176)
- Recessive amyotrophic lateral sclerosis families with the D90A SOD1 mutation share a common founder: evidence for a linked protective factor. (1998) (175)
- Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8. (1996) (175)
- Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease (2009) (175)
- DSM‐IV combined type ADHD shows familial association with sibling trait scores: A sampling strategy for QTL linkage (2008) (170)
- WHAP: haplotype-based association analysis (2007) (170)
- A diffusion tensor imaging study of structural dysconnectivity in never-medicated, first-episode schizophrenia (2007) (170)
- Endothelial Nitric Oxide Gene Haplotypes and Risk of Cerebral Small-Vessel Disease (2004) (167)
- Whole genome linkage scan of recurrent depressive disorder from the depression network study. (2005) (164)
- Meta‐Analysis of Genome‐Wide Scans Provides Evidence for Sex‐ and Site‐Specific Regulation of Bone Mass (2006) (161)
- Meta‐Analysis of Genome‐wide Linkage Studies in BMI and Obesity (2007) (159)
- Genetics of disc degeneration (2006) (156)
- The TRP2 Allele of COL9A2 is an Age-Dependent Risk Factor for the Development and Severity of Intervertebral Disc Degeneration (2005) (154)
- Prenatal Immune Challenge Is an Environmental Risk Factor for Brain and Behavior Change Relevant to Schizophrenia: Evidence from MRI in a Mouse Model (2009) (153)
- Differences in distribution of ages of onset in males and females with schizophrenia (1998) (153)
- GWASdb v2: an update database for human genetic variants identified by genome-wide association studies (2015) (144)
- Predicting Mendelian Disease-Causing Non-Synonymous Single Nucleotide Variants in Exome Sequencing Studies (2013) (144)
- Association of the Taq I Allele in Vitamin D Receptor With Degenerative Disc Disease and Disc Bulge in a Chinese Population (2006) (140)
- The common genetic liability between schizophrenia and bipolar disorder: A review. (2001) (138)
- Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters (2009) (133)
- Gray matter in first-episode schizophrenia before and after antipsychotic drug treatment. Anatomical likelihood estimation meta-analyses with sample size weighting. (2011) (132)
- Depression in college: depressive symptoms and personality factors in Beijing and Hong Kong college freshmen. (2008) (132)
- Prevalence, psychosocial correlates and service utilization of depressive and anxiety disorders in Hong Kong: the Hong Kong Mental Morbidity Survey (HKMMS) (2015) (131)
- Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine (1996) (129)
- Alterations in Gastric Microbiota After H. Pylori Eradication and in Different Histological Stages of Gastric Carcinogenesis (2017) (127)
- Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs. (2001) (126)
- Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships. (2004) (124)
- GENECOUNTING: haplotype analysis with missing genotypes (2002) (124)
- ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai (2009) (122)
- Impaired intellect and memory: a missing link between genetic risk and schizophrenia? (2010) (118)
- Association of the asporin D14 allele with lumbar-disc degeneration in Asians. (2008) (116)
- Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. (2010) (115)
- Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry (2017) (114)
- Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China (2012) (113)
- Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene. (2004) (112)
- Distribution of symptom dimensions across Kraepelinian divisions (2006) (110)
- Relationship between in utero exposure to influenza epidemics and risk of schizophrenia in Denmark (1996) (109)
- Mismatch negativity in schizophrenia: a family study (2004) (108)
- Brain volumes in familial and non-familial schizophrenic probands and their unaffected relatives. (2002) (108)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data (2019) (107)
- GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications (2013) (107)
- Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease (1997) (107)
- TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease. (2005) (107)
- Substantial shared genetic influences on schizophrenia and event-related potentials. (2007) (107)
- Scholastic achievement at age 16 and risk of schizophrenia and other psychoses: a national cohort study (2007) (106)
- Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP‐25, and 5HT1B (2005) (106)
- Autoimmune diseases in the pedigrees of schizophrenic and control subjects (1996) (105)
- Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants contributing to lipid levels and coronary artery disease (2017) (103)
- The Heritability of Attitude Toward Economic Risk (2009) (102)
- Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects (1997) (101)
- Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population. (2010) (101)
- Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease (2015) (101)
- Schizophrenia following pre-natal exposure to influenza epidemics between 1939 and 1960. (1992) (101)
- Prognostic modelling of therapeutic interventions in amyotrophic lateral sclerosis (2002) (100)
- Faster Haplotype Frequency Estimation Using Unrelated Subjects (2002) (100)
- Genomic Diversity of Epstein-Barr Virus Genomes Isolated from Primary Nasopharyngeal Carcinoma Biopsy Samples (2014) (100)
- SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. (2005) (99)
- HYST: a hybrid set-based test for genome-wide association studies, with application to protein-protein interaction-based association analysis. (2012) (99)
- Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant. (2013) (99)
- Cognitive style in bipolar disorder (2005) (97)
- Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing. (2013) (96)
- The early auditory gamma-band response is heritable and a putative endophenotype of schizophrenia. (2011) (96)
- Model-free linkage analysis using likelihoods. (1995) (95)
- Molecular genetic gene–environment studies using candidate genes in schizophrenia: A systematic review (2013) (95)
- Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis (2014) (93)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- Parental familial vulnerability, family environment, and their interactions as predictors of depressive symptoms in adolescents. (2004) (92)
- A neurochemical approach to valuation sensitivity over gains and losses (2009) (91)
- Family history of autoimmune diseases in psychosis (1996) (91)
- A Genome-Wide Scan of 1842 DNA Markers for Allelic Associations with General Cognitive Ability: A Five-Stage Design Using DNA Pooling and Extreme Selected Groups (2001) (91)
- The serotonin transporter gene as a QTL for ADHD (2005) (89)
- Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia (1996) (89)
- Abnormal P300 in people with high risk of developing psychosis (2008) (87)
- Uncovering the total heritability explained by all true susceptibility variants in a genome‐wide association study (2011) (86)
- Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. (2014) (86)
- Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia (2010) (85)
- Hippocampal volume in familial and nonfamilial schizophrenic probands and their unaffected relatives (2003) (85)
- Longitudinal heritability of childhood aggression (2016) (85)
- Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain (2014) (84)
- Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese (2015) (84)
- Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations (2021) (83)
- Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer. (2019) (82)
- Genetic overlap between bipolar illness and event-related potentials (2007) (82)
- Familiality of symptom dimensions in schizophrenia (2001) (82)
- Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis (2014) (81)
- A controlled study of brain structure in monozygotic twins concordant and discordant for schizophrenia (2004) (81)
- Sense of hyper-positive self and response to cognitive therapy in bipolar disorder (2005) (81)
- Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups (2021) (81)
- CLUSTAG: hierarchical clustering and graph methods for selecting tag SNPs (2005) (81)
- A SNP resource for human chromosome 22: extracting dense clusters of SNPs from the genomic sequence. (2001) (80)
- Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A)gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects. (2002) (80)
- European Bone Mineral Density Loci Are Also Associated with BMD in East-Asian Populations (2010) (80)
- Aerobic exercise and yoga improve neurocognitive function in women with early psychosis (2015) (79)
- Linnorm: improved statistical analysis for single cell RNA-seq expression data (2017) (76)
- ELF1 is associated with systemic lupus erythematosus in Asian populations. (2011) (75)
- Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese. (2010) (74)
- Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. (2008) (73)
- Long-term effects of discontinuation from antipsychotic maintenance following first-episode schizophrenia and related disorders: a 10 year follow-up of a randomised, double-blind trial. (2018) (73)
- Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening. (2011) (73)
- A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups (2014) (73)
- Circulating Levels of Adipocyte and Epidermal Fatty Acid–Binding Proteins in Relation to Nephropathy Staging and Macrovascular Complications in Type 2 Diabetic Patients (2009) (72)
- The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B (2015) (72)
- Parental phenotypes in family-based association analysis. (2005) (72)
- Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma (2021) (71)
- Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese. (2012) (71)
- Substantial Genetic Overlap Between Neurocognition and Schizophrenia (2007) (70)
- Heroin abuse accelerates biological aging: a novel insight from telomerase and brain imaging interaction (2013) (69)
- Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans. (2011) (68)
- Neurocognitive deficits in first‐episode schizophrenic patients and their first‐degree relatives (2007) (67)
- Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma (2016) (67)
- Analysis of clozapine response and polymorphisms of the dopamine D4 receptor gene (DRD4) in schizophrenic patients. (1995) (67)
- SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese (2012) (65)
- Common genetic variants regulating ADD3 gene expression alter biliary atresia risk. (2013) (65)
- Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study (2018) (65)
- Genome-Wide Association Study of Hepatocellular Carcinoma in Southern Chinese Patients with Chronic Hepatitis B Virus Infection (2011) (65)
- Robust Association Tests Under Different Genetic Models, Allowing for Binary or Quantitative Traits and Covariates (2011) (65)
- Polygenic risk score increases schizophrenia liability through cognition-relevant pathways (2018) (64)
- Reaction time of the Continuous Performance Test is an endophenotypic marker for schizophrenia: A study of first-episode neuroleptic-naive schizophrenia, their non-psychotic first-degree relatives and healthy population controls (2007) (63)
- A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. (2005) (63)
- No association between (AAT)n repeats in the cannabinoid receptor gene (CNR1) and heroin abuse in a Chinese population (2000) (62)
- A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophrenia (2009) (62)
- Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes (2017) (61)
- DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: No evidence for association (2005) (60)
- Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset (2011) (60)
- Application of Logistic Regression to Case-Control Association Studies Involving Two Causative Loci (2005) (60)
- A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2020) (60)
- Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as Hypertension Susceptibility Genes in Han Chinese with a Genome-Wide Gene-Based Association Study (2012) (59)
- A Model-Fitting Implementation of the DeFries-Fulker Model for Selected Twin Data (2003) (59)
- Familial psychiatric presentation of Huntington's disease. (1996) (58)
- Association analysis between dopamine receptor genes and bipolar affective disorder (1999) (57)
- Haplotype Association Analysis of Discrete and Continuous Traits Using Mixture of Regression Models (2004) (56)
- HLAreporter: a tool for HLA typing from next generation sequencing data (2015) (56)
- GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits (2018) (56)
- Genome-Wide Copy Number Analysis Uncovers a New HSCR Gene: NRG3 (2012) (56)
- Dermatoglyphics and Schizophrenia: A meta-analysis and investigation of the impact of obstetric complications upon a–b ridge count (2005) (56)
- QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes (2019) (56)
- Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study (2014) (56)
- Exploring the function of genetic variants in the non-coding genomic regions: approaches for identifying human regulatory variants affecting gene expression (2015) (55)
- High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers. (2006) (55)
- No association between T102C polymorphism of serotonin-2A receptor gene and clinical phenotypes of Chinese schizophrenic patients (2001) (55)
- Lifetime Prevalence and Correlates of Schizophrenia-Spectrum, Affective, and Other Non-affective Psychotic Disorders in the Chinese Adult Population (2017) (55)
- Mutations in the NRG1 gene are associated with Hirschsprung disease (2011) (55)
- Linkage to Chromosome 1p36 for Attention-Deficit/Hyperactivity Disorder Traits in School and Home Settings (2008) (54)
- A Knowledge-Based Weighting Framework to Boost the Power of Genome-Wide Association Studies (2010) (54)
- Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study (2016) (54)
- Association between the alpha(1a) calcium channel gene CACNA1A and idiopathic generalized epilepsy. (2001) (53)
- HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B. (2013) (53)
- Phenotypic and population differences in the association between CILP and lumbar disc disease (2007) (53)
- 5-HT2A receptor and bipolar affective disorder: association studies in affected patients (1997) (52)
- Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. (2000) (52)
- Common variants on Xq28 conferring risk of schizophrenia in Han Chinese. (2014) (52)
- The relationship of fatigue to mental and physical health in a community sample (2005) (52)
- HLA‐B*38:02:01 predicts carbimazole/methimazole‐induced agranulocytosis (2016) (52)
- High risk Epstein‐Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma (2019) (50)
- Olanzapine: concordant response in monozygotic twins with schizophrenia (2001) (50)
- Further exploration of a latent class typology of schizophrenia (1996) (50)
- COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2009) (50)
- Do obstetric complications cause the earlier age at onset in male than female schizophrenics? (1996) (49)
- Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder (2019) (49)
- Improving polygenic risk prediction from summary statistics by an empirical Bayes approach (2017) (49)
- Single‐nucleotide polymorphism‐mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma (2008) (49)
- Statistics and the nature of depression (1993) (49)
- Planning genetic studies in human stroke: Sample size estimates based on family history data (2002) (49)
- Properties of Structured Association Approaches to Detecting Population Stratification (2005) (48)
- Neuregulin-1 and the P300 waveform—A preliminary association study using a psychosis endophenotype (2008) (48)
- Schizotypal personality traits in nonpsychotic relatives are associated with positive symptoms in psychotic probands. (2003) (47)
- Genetic overlap between P300, P50, and duration mismatch negativity (2006) (47)
- Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development. (2018) (47)
- Variance components models for gene-environment interaction in quantitative trait locus linkage analysis. (2002) (47)
- Artificial neural networks and decision tree model analysis of liver cancer proteomes. (2007) (47)
- Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese (2008) (47)
- Optimal selection strategies for QTL mapping using pooled DNA samples (2002) (46)
- Variance‐components QTL linkage analysis of selected and non‐normal samples: Conditioning on trait values (2000) (46)
- Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene. (2006) (46)
- RET and NRG1 interplay in Hirschsprung disease (2013) (45)
- Logistic regression analysis of twin data: Estimation of parameters of the multifactorial liability-threshold model (1994) (45)
- dbPSHP: a database of recent positive selection across human populations (2013) (45)
- Heritability of Schneider's first-rank symptoms (2002) (45)
- Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese. (2011) (44)
- Association analysis of polymorphisms in the DRD4 gene and heroin abuse in Chinese subjects. (2000) (43)
- Association Analysis in a Variance Components Framework (2001) (43)
- Further evidence for shared genetic effects between psychotic bipolar disorder and P50 suppression: A combined twin and family study (2008) (42)
- Does prenatal exposure to influenza in mice induce pyramidal cell disarray in the dorsal hippocampus? (1995) (42)
- Association of apolipoprotein E epsilon 4 allele with bulbar-onset motor neuron disease. (1996) (42)
- A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained (2010) (42)
- A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays (2005) (42)
- Cognitive style, personality and vulnerability to postnatal depression (2010) (42)
- Transmission/disequilibrium tests for multiallelic loci. (1997) (42)
- Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma (2008) (42)
- Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development (2015) (42)
- Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese (2013) (41)
- Dysfunction of Myosin Light‐Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically‐Engineered Rats (2017) (41)
- Association analysis of dopamine D2-like receptor genes and methamphetamine abuse (2004) (41)
- Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study. (2011) (41)
- Assessment of gene‐by‐sex interaction effect on bone mineral density (2012) (41)
- CD209 (DC-SIGN) −336A>G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese (2010) (41)
- Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4 (2008) (41)
- Further evidence for anomalies in the hand-prints of patients with schizophrenia: a study of secondary creases (1994) (41)
- Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3 (2012) (41)
- Chemotherapy-Induced Cognitive Impairment Is Associated with Cytokine Dysregulation and Disruptions in Neuroplasticity (2018) (40)
- Susceptibility genes for a trait measure of attention deficit hyperactivity disorder: a pilot study in a non-clinical sample of twins (2001) (40)
- CAUSALdb: a database for disease/trait causal variants identified using summary statistics of genome-wide association studies (2019) (40)
- MGAS: a powerful tool for multivariate gene-based genome-wide association analysis (2014) (39)
- The Roles of PAX6 and SOX2 in Myopia: lessons from the 1958 British Birth Cohort. (2007) (39)
- Burden of rare variants in ALS genes influences survival in familial and sporadic ALS (2017) (39)
- Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events. (2018) (39)
- Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation. (1999) (39)
- Early intervention and evaluation for adult‐onset psychosis: the JCEP study rationale and design (2014) (39)
- An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population (2008) (38)
- Exploring genetic associations with ceRNA regulation in the human genome (2017) (38)
- The trimmed-haplotype test for linkage disequilibrium. (2000) (38)
- Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9) (2015) (38)
- Childhood schizotypy and positive symptoms in schizophrenic patients predict schizotypy in relatives (2000) (38)
- Epidermal fatty-acid-binding protein: a new circulating biomarker associated with cardio-metabolic risk factors and carotid atherosclerosis. (2008) (38)
- Power comparison of parametric and nonparametric linkage tests in small pedigrees. (2000) (37)
- Robust and rapid algorithms facilitate large-scale whole genome sequencing downstream analysis in an integrative framework (2017) (37)
- Trans-ethnic meta-analysis of genome-wide association studies for Hirschsprung disease. (2016) (36)
- T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures. (2006) (36)
- 102T/C polymorphism of serotonin receptor type 2A gene is not associated with schizophrenia in either Chinese or British populations. (1999) (36)
- Predicting regulatory variants with composite statistic (2016) (36)
- Genetic variant representation, annotation and prioritization in the post-GWAS era (2012) (36)
- Analysis of CAG/CTG repeat size in chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method (1998) (36)
- Epistasis in Quantitative Trait Locus Linkage Analysis: Interaction or Main Effect? (2004) (36)
- A1166C genetic variation of the angiotensin II type I receptor gene and susceptibility to coronary heart disease: collaborative of 53 studies with 20,435 cases and 23,674 controls. (2010) (36)
- Amelioration of X-Linked Related Autophagy Failure in Danon Disease With DNA Methylation Inhibitor (2016) (36)
- Actionable secondary findings from whole-genome sequencing of 954 East Asians (2017) (36)
- Comparison of the family history with the family study method: report from the Camberwell Collaborative Psychosis Study. (1997) (36)
- Exploring the predictive power of polygenic scores derived from genome‐wide association studies: a study of 10 complex traits (2017) (35)
- Significance of the Myxovirus Resistance A (MxA) Gene — 123C>A Single-Nucleotide Polymorphism in Suppressed Interferon β Induction of Severe Acute Respiratory Syndrome Coronavirus Infection (2010) (35)
- An association analysis of microsatellite markers across the Prader–Willi/Angelman critical region on chromosome 15 (q11‐13) and autism spectrum disorder (2005) (35)
- The role of gene variants in the pathogenesis of neurodegenerative disorders as revealed by next generation sequencing studies: a review (2017) (35)
- regBase: whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants (2019) (35)
- Joint linkage of multiple loci for a complex disorder. (1993) (35)
- Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits (2016) (35)
- Analysis of multifactorial disease (2000) (35)
- Identification of LTBP2 on chromosome 14q as a novel candidate gene for bone mineral density variation and fracture risk association. (2008) (34)
- A Genome-Wide Linkage and Association Scan Reveals Novel Loci for Hypertension and Blood Pressure Traits (2012) (34)
- Jumping to conclusions, general intelligence, and psychosis liability: findings from the multi-centre EU-GEI case-control study (2019) (34)
- Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia (2006) (34)
- PacBio But Not Illumina Technology Can Achieve Fast, Accurate and Complete Closure of the High GC, Complex Burkholderia pseudomallei Two-Chromosome Genome (2017) (34)
- Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus. (2015) (34)
- C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism (2020) (34)
- Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma. (2016) (34)
- Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells. (2020) (33)
- The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research (2014) (33)
- Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men. (2008) (33)
- Using Glycosylated Hemoglobin to Define the Metabolic Syndrome in United States Adults (2010) (33)
- Serotonergic polymorphisms and psychotic disorders in populations from North Spain (2004) (33)
- Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension. (2009) (33)
- cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes (2017) (32)
- The Maudsley environmental risk score for psychosis (2018) (32)
- Distinguishing Population Stratification from Genuine Allelic Effects with Mx: Association of ADH2 with Alcohol Consumption (1999) (32)
- A note on calculation of empirical P values from Monte Carlo procedure. (2003) (32)
- Optimal Sibship Selection for Genotyping in Quantitative Trait Locus Linkage Analysis (2001) (32)
- Life events before psychotic episodes: do clinical and social variables affect the relationship? (1996) (32)
- Impulsivity, cognitive function, and their relationship in heroin-dependent individuals (2013) (32)
- Adjusting for Covariates in Variance Components QTL Linkage Analysis (2004) (31)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine (2017) (31)
- Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population (2009) (31)
- PMCA4 (ATP2B4) Mutation in Familial Spastic Paraplegia (2014) (31)
- Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects. (2020) (30)
- Risk of Schizophrenia and Age Difference with Older Siblings (1993) (30)
- Heritability of hallucinations in adolescent twins (2012) (30)
- Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy (2002) (30)
- Prenatal immune activation alters the adult neural epigenome but can be partly stabilised by a n-3 polyunsaturated fatty acid diet (2018) (30)
- Heritability Estimates for Psychotic Disorders (2016) (30)
- Plasma adrenomedullin level is related to a single nucleotide polymorphism in the adrenomedullin gene. (2011) (30)
- Association of ICAM3 Genetic Variant with Severe Acute Respiratory Syndrome (2007) (30)
- Positive effects of low LDL-C and statins on bone mineral density: an integrated epidemiological observation analysis and Mendelian Randomization study (2019) (30)
- Assessment of linkage and association of 13 genetic loci with bone mineral density (2006) (30)
- A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15 q 25 (2010) (29)
- Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes (2012) (29)
- Familiality of clinical characteristics in schizophrenia. (2002) (29)
- Analytic power calculation for QTL linkage analysis of small pedigrees (2001) (29)
- Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study. (2016) (29)
- Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians. (2014) (29)
- A transmission/disequilibrium study of the DRB1*04 gene locus on chromosome 6p21.3 with schizophrenia (1998) (28)
- PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion (2015) (28)
- Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia (vol 99, pg 13675, 2002) (2002) (28)
- Rare coding variants in MAPK7 predispose to adolescent idiopathic scoliosis (2017) (28)
- Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (2009) (28)
- Soluble interleukin 2 receptor levels in families of people with schizophrenia (2002) (27)
- Efficient SNP‐based tests of association for quantitative phenotypes using pooled DNA (2001) (27)
- Segregation Analysis of the NIMH Collaborative Study. Family Data on Bipolar Disorder (1992) (27)
- Correlated evolution of transcription factors and their binding sites (2011) (27)
- A program for the monte carlo evaluation of significance of the extended transmission/disequilibrium test. (1999) (26)
- Population differences in the International Multi‐Centre ADHD Gene Project (2008) (26)
- The relationship between predisposing factors, premorbid function and symptom dimensions in psychosis: an integrated approach (2002) (26)
- Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study. (2014) (26)
- GWASdb v 2 : an update database for human genetic variants identified by genome-wide association studies (2015) (26)
- Fine Mapping of the NRG1 Hirschsprung's Disease Locus (2011) (26)
- Normal cerebral asymmetry in familial and non-familial schizophrenic probands and their unaffected relatives (2004) (25)
- Relationship of plasma interleukin-6 and its genetic variants with hypertension in Hong Kong Chinese. (2011) (25)
- MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy (2011) (25)
- Linkage disequilibrium analysis of the CHRNA7 gene and its partially duplicated region in schizophrenia (2007) (25)
- Correlation and familial aggregation of dimensions of psychosis in affected sibling pairs from China (2001) (25)
- Association of CDX1 binding site of periostin gene with bone mineral density and vertebral fracture risk (2010) (25)
- Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation (2011) (25)
- Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron–astrocyte–microglia dysregulation (2018) (25)
- The genetic and environmental influences of event‐related gamma oscillations on bipolar disorder (2011) (25)
- Rare inborn errors associated with chronic hepatitis B virus infection * (2012) (25)
- Exome sequencing reveals a high genetic heterogeneity on familial Hirschsprung disease (2015) (25)
- Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations (2021) (25)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- Effect of Damaging Rare Mutations in Synapse-Related Gene Sets on Response to Short-term Antipsychotic Medication in Chinese Patients With Schizophrenia: A Randomized Clinical Trial (2018) (25)
- MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes (2020) (24)
- Daily use of high-potency cannabis is associated with more positive symptoms in first-episode psychosis patients: the EU-GEI case–control study (2020) (24)
- FastPval: a fast and memory efficient program to calculate very low P-values from empirical distribution (2010) (24)
- Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction (2021) (24)
- Genetics of lumbar disk degeneration: technology, study designs, and risk factors. (2011) (24)
- Relationship of birth season to clinical features, family history, and obstetric complications in schizophrenia (1996) (24)
- Genome-wide copy number variation study in anorectal malformations. (2013) (24)
- Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density. (2012) (24)
- Allele association studies with SSR and SNP markers at known physical distances within a 1 Mb region embracing the ALDH2 locus in the Japanese, demonstrates linkage disequilibrium extending up to 400 kb. (2000) (24)
- The Effect of Genotype and Pedigree Error on Linkage Analysis: Analysis of Three Asthma Genome Scans (2001) (24)
- Influence of Alzheimer's disease genes on cognitive decline: the Guangzhou Biobank Cohort Study (2014) (24)
- Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals. (2021) (23)
- Schizophrenia in Afro-Caribbeans in the U.K. following prenatal exposure to the 1957 A2 influenza epidemic (1992) (23)
- RET Mutational Spectrum in Hirschsprung Disease: Evaluation of 601 Chinese Patients (2011) (23)
- Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations (2015) (23)
- HIV-1 Tat and methamphetamine co-induced oxidative cellular injury is mitigated by N-acetylcysteine amide (NACA) through rectifying mTOR signaling. (2018) (23)
- Combining functional and linkage disequilibrium information in the selection of tag SNPs (2007) (23)
- GABAA receptor subunit genes as candidate genes for bipolar affective disorder—an association analysis (1992) (23)
- Commingling Analysis of Intraocular Pressure and Glaucoma in an Older Australian Population (2004) (23)
- Risk of schizophrenia and age difference with older siblings: Evidence for a maternal viral infection hypothesis? (1993) (23)
- Etiology of developmental spinal stenosis: A genome‐wide association study (2017) (22)
- MRI Predicts Remission at 1 Year in First-Episode Schizophrenia in Females with Larger Striato-Thalamic Volumes (2014) (22)
- The GENESiS study (1999) (22)
- Shifting paradigms in gene-mapping methodology for complex traits. (2001) (22)
- The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia (2005) (22)
- Genome‐Wide Haplotype Association Mapping in Mice Identifies a Genetic Variant in CER1 Associated With BMD and Fracture in Southern Chinese Women (2009) (22)
- Impact and Quantification of the Sources of Error in DNA Pooling Designs (2009) (21)
- Correction: Genome-Wide Copy Number Analysis Uncovers a New HSCR Gene: NRG3 (2012) (21)
- High-sensitivity troponin I and B-type natriuretic peptide biomarkers for prediction of cardiovascular events in patients with coronary artery disease with and without diabetes mellitus (2019) (21)
- Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs (2020) (21)
- Genome-Wide Association Analysis with Gray Matter Volume as a Quantitative Phenotype in First-Episode Treatment-Naïve Patients with Schizophrenia (2013) (21)
- Impact of Genetic Loci Identified in Genome-Wide Association Studies on Diabetic Retinopathy in Chinese Patients With Type 2 Diabetes. (2016) (21)
- The Epidemiology of Schizophrenia: Gene–environment correlation and interaction in schizophrenia (2002) (21)
- Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders (2021) (21)
- Application of genome-wide SNP data for uncovering pairwise relationships and quantitative trait loci (2009) (21)
- A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese. (2011) (21)
- Mapping of a Hirschsprung's disease locus in 3p21 (2008) (21)
- Systematic investigation of the relationship between high myopia and polymorphisms of the MMP2, TIMP2, and TIMP3 genes by a DNA pooling approach. (2011) (21)
- Evaluation of proteoglycan gene polymorphisms as risk factors in the genetic susceptibility to high myopia. (2011) (20)
- Identification of Two Sex-Specific Quantitative Trait Loci in Chromosome 11q for Hip Bone Mineral Density in Chinese (2006) (20)
- Association of a single nucleotide polymorphism in the CD209 (DC-SIGN) promoter with SARS severity. (2010) (20)
- A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder (2019) (20)
- Application of multi‐locus analytical methods to identify interacting loci in case‐control studies (2007) (19)
- Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy (2018) (19)
- Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis (2018) (19)
- PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling. (2015) (19)
- Meta-analysis of gene-based genome-wide association studies of bone mineral density in Chinese and European subjects (2011) (19)
- Haplotype Analysis Reveals a Possible Founder Effect of RET Mutation R114H for Hirschsprung's Disease in the Chinese Population (2010) (19)
- The Hong Kong mental morbidity survey: background and study design. (2014) (19)
- A fast and powerful W-test for pairwise epistasis testing (2016) (18)
- A Randomized Controlled Study of Cognitive Therapy for Relapse Prevention for Bipolar Affective Disorder (2016) (18)
- Age-Biomarkers-Clinical Risk Factors for Prediction of Cardiovascular Events in Patients With Coronary Artery Disease (2018) (18)
- Ascertainment Through Family History of Disease Often Decreases the Power of Family-based Association Studies (2007) (18)
- VannoPortal: multiscale functional annotation of human genetic variants for interrogating molecular mechanism of traits and diseases (2021) (18)
- Multiple testing and power calculations in genetic association studies. (2011) (18)
- CHIP: Defining a dimension of the vulnerability to attention deficit hyperactivity disorder (ADHD) using sibling and individual data of children in a community‐based sample (2003) (18)
- A powerful conditional gene‐based association approach implicated functionally important genes for schizophrenia (2018) (18)
- Confirmation of linkage to chromosome 1q for spine bone mineral density in southern Chinese (2006) (18)
- Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality (2007) (18)
- Genetic Analyses of a Three Generation Family Segregating Hirschsprung Disease and Iris Heterochromia (2013) (17)
- Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies (2010) (17)
- Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population (2008) (17)
- Chronic Ketamine Exposure Causes White Matter Microstructural Abnormalities in Adolescent Cynomolgus Monkeys (2017) (17)
- CNV analysis in Chinese children of mental retardation highlights a sex differentiation in parental contribution to de novo and inherited mutational burdens (2016) (17)
- Tractography-based classification in distinguishing patients with first-episode schizophrenia from healthy individuals (2019) (17)
- Local True Discovery Rate Weighted Polygenic Scores Using GWAS Summary Data (2016) (17)
- Schizophrenia in Afro-Caribbeans in the UK following prenatal exposure to the 1957 A2 influenza pandemic (1993) (17)
- Identification of Genes with Allelic Imbalance on 6p Associated with Nasopharyngeal Carcinoma in Southern Chinese (2011) (17)
- Apolipoprotein e genotype and late paraphrenia (1995) (17)
- Cerebral asymmetry in 14 year olds born very preterm (2006) (16)
- Prenatal exposure to influenza epidemics and risk of mental retardation (2005) (16)
- Gene Network Analysis of Candidate Loci for Human Anorectal Malformations (2013) (16)
- Association of the serotonin transporter gene, neuroticism and smoking behaviours (2008) (16)
- Variance Components Models for Gene–Environment Interaction in Quantitative Trait Locus Linkage Analysis (2002) (16)
- Uncovering the genetic lesions underlying the most severe form of Hirschsprung disease by whole-genome sequencing (2018) (16)
- −459C>T point mutation in 5′ non‐coding region of human GJB1 gene is linked to X‐linked Charcot‐Marie‐Tooth neuropathy (2009) (16)
- Commingling analyses of central corneal thickness and adjusted intraocular pressure in an older Australian population. (2010) (16)
- The role of dopamine dysregulation and evidence for the transdiagnostic nature of elevated dopamine synthesis in psychosis: a positron emission tomography (PET) study comparing schizophrenia, delusional disorder, and other psychotic disorders (2020) (16)
- DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics (2020) (15)
- Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders (2019) (15)
- Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals (2016) (15)
- A single low dose of valproic acid in late prenatal life alters postnatal behavior and glutamic acid decarboxylase levels in the mouse (2016) (15)
- Predicting first-episode psychosis patients who will never relapse over 10 years (2018) (15)
- WITER: a powerful method for estimation of cancer-driver genes using a weighted iterative regression modelling background mutation counts (2019) (15)
- A fast and powerful W-test for pairwise epistasis testing (2016) (15)
- Design and Analysis of Association Studies using Pooled DNA from Large Twin Samples (2006) (15)
- Visual working memory deterioration preceding relapse in psychosis (2016) (15)
- Estimated haplotype counts from case-control samples cannot be treated as observed counts. (2006) (15)
- Linnorm: improved statistical analysis for single cell RNA-seq expression data (2017) (14)
- Seasonality, prenatal influenza exposure, and schizophrenia. (1999) (14)
- Homozygosity Mapping on a Single Patient—Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data (2011) (14)
- Binge drinking trends in a UK community‐based sample (2003) (14)
- Understanding the genetic predisposition to anorexia nervosa (1999) (14)
- Number of older siblings of individuals diagnosed with schizophrenia (2001) (14)
- Mutations in Hnrnpa1 cause congenital heart defects (2018) (14)
- DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics (2020) (14)
- Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population. (2013) (14)
- Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use. (2019) (14)
- Estimation of Sib-Pair IBD Sharing and Multipoint Polymorphism Information Content by Linear Regression (2002) (14)
- Gene‐Based Meta‐Analysis of Genome‐Wide Association Study Data Identifies Independent Single‐Nucleotide Polymorphisms in ANXA6 as Being Associated With Systemic Lupus Erythematosus in Asian Populations (2015) (14)
- Likelihood ratio tests for linkage and linkage disequilibrium: asymptotic distribution and power. (1996) (14)
- Identification of a wide spectrum of ciliary gene mutations in nonsyndromic biliary atresia patients implicates ciliary dysfunction as a novel disease mechanism (2021) (14)
- Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes (2018) (14)
- Segregation analysis of complex phenotypes: an application to schizophrenia and auditory P300 latency. (1994) (14)
- SKM-SNP: SNP markers detection method (2010) (13)
- Erratum: Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia (Proceedings of the National Academy of Sciences of the United States of America (October 15, 2002) 99:21 (13675-13680)) (2002) (13)
- Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups. (2018) (13)
- A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings (2011) (13)
- Combining the sibling disequilibrium test and transmission/disequilibrium test for multiallelic markers. (1999) (13)
- Segregation analysis of complex phenotypes: An application to schizophrenia and auditory P300 latency (1993) (13)
- IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis (2009) (13)
- Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates (2010) (13)
- A quick and simple method for detecting subjects with abnormal genetic background in case-control samples. (2002) (13)
- Identification of QTL genes for BMD variation using both linkage and gene-based association approaches (2011) (13)
- A Note on the Power to Detect Transmission Distortion in Parent-Child Trios via the Transmission Disequilibrium Test (2006) (13)
- Investigation of the Ability of Haplotype Association and Logistic Regression to Identify Associated Susceptibility Loci (2006) (13)
- DESE: estimating driver tissues by selective expression of genes associated with complex diseases or traits (2019) (13)
- OpenADAM: an open source genome-wide association data management system for Affymetrix SNP arrays (2008) (13)
- Quantitative Trait Locus Analysis of Candidate Gene Alleles Associated With Attention Deficit Hyperactivity Disorder ( ADHD ) in Five Genes : DRD 4 , DAT 1 , DRD 5 , SNAP-25 , and 5 HT 1 B (2005) (12)
- Causal relationships between blood lipids and depression phenotypes: a Mendelian randomisation analysis (2020) (12)
- Generic number systems and haplotype analysis (2003) (12)
- The Effect of Oxytocin on Social and Non-Social Behaviour and Striatal Protein Expression in C57BL/6N Mice (2015) (12)
- Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study (2016) (12)
- Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism (2015) (12)
- CFTR founder mutation causes protein trafficking defects in Chinese patients with cystic fibrosis (2016) (12)
- Title Genome-wide association study in asian populations identifies variants in ETS 1 and WDFY 4 associated with systemic lupus erythematosus (2010) (12)
- Integrating Clinical Data and Imputed Transcriptome from GWAS to Uncover Complex Disease Subtypes: Applications in Psychiatry and Cardiology. (2019) (12)
- Targeted Next‐Generation Sequencing on Hirschsprung Disease: A Pilot Study Exploits DNA Pooling (2014) (12)
- FAPI: Fast and accurate P-value Imputation for genome-wide association study (2015) (11)
- The Genes We Inherit and Those We Don’t: Maternal Genetic Nurture and Child BMI Trajectories (2020) (11)
- A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population (2011) (11)
- Effect Size Measures in Genetic Association Studies and Age-Conditional Risk Prediction (2010) (11)
- Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. (2014) (11)
- SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants (2015) (11)
- Inheritance-mode specific pathogenicity prioritization (ISPP) for human protein coding genes (2016) (11)
- Major genetic effects in glaucoma: commingling analysis of optic disc parameters in an older Australian population. (2009) (11)
- Sacral agenesis: a pilot whole exome sequencing and copy number study (2016) (11)
- Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease (2020) (11)
- Evaluation of bi-directional causal association between depression and cardiovascular diseases: a Mendelian randomization study (2020) (11)
- A three-stage genome-wide association study combining multilocus test and gene expression analysis for young-onset hypertension in Taiwan Han Chinese. (2014) (11)
- Pathway-Based Single-Cell RNA-Seq Classification, Clustering, and Construction of Gene-Gene Interactions Networks Using Random Forests (2020) (10)
- Intermediate confounding in trio relationships: The importance of complete data in effect size estimation (2020) (10)
- Predicting the number and sizes of IBD regions among family members and evaluating the family size requirement for linkage studies (2008) (10)
- The contribution of risk factors to blood pressure heritability estimates in young adults: the East flanders prospective twin study. (2004) (10)
- mTCTScan: a comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers (2017) (10)
- Schizophrenia: Sex and familial morbidity (1994) (10)
- Immune dysregulation in depression: Evidence from genome-wide association (2020) (10)
- Genetically deprived vitamin D exposure predisposes to atrial fibrillation. (2017) (10)
- Role of Genetic Variants in the Gene Encoding Lipocalin-2 in the Development of Elevated Blood Pressure (2011) (10)
- Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes (2016) (10)
- Genetic analysis of recently identified osteoporosis susceptibility genes in southern Chinese. (2013) (10)
- IGG: A tool to integrate GeneChips for genetic studies (2007) (10)
- Cancer gene mutations in congenital pulmonary airway malformation patients (2019) (10)
- [Influence of serotonergic transmission on response to olanzapine]. (2002) (10)
- CLUMPHAP: a simple tool for performing haplotype‐based association analysis (2008) (9)
- Schizophrenic births in England and Wales and their relationship to infectious diseases (1993) (9)
- An Exome-Chip Association Analysis in Chinese Subjects Reveals a Functional Missense Variant of GCKR That Regulates FGF21 Levels (2017) (9)
- The Effect of Paternal Age on Relapse in First-Episode Schizophrenia (2015) (9)
- Coagulation factors and the incidence of COVID-19 severity: Mendelian randomization analyses and supporting evidence (2021) (9)
- Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease (2014) (9)
- Genetic Overlap Between Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in SHANK2 Gene (2021) (9)
- Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice (2016) (9)
- Ultrafast and scalable variant annotation and prioritization with big functional genomics data (2020) (9)
- Ten-year employment patterns of patients with first-episode schizophrenia-spectrum disorders: comparison of early intervention and standard care services. (2019) (9)
- Neurological Soft Signs Are Associated With Altered Cerebellar-Cerebral Functional Connectivity in Schizophrenia. (2021) (9)
- Prevalence of anxiety disorders in community dwelling older adults in Hong Kong (2016) (9)
- Title Identification of igf 1 , slc 4 a 4 , wwox , and sfmbt 1 as hypertension susceptibility genes in han chinese with a genome-wide gene-based association study (2012) (9)
- Family-based association tests for quantitative traits using pooled DNA (2002) (9)
- Strategies for the Study of Neuropsychiatric Disorders Using Endophenotypes in Developing Countries: A Potential Databank from China (2010) (9)
- Polygenic scores for UK Biobank scale data (2018) (9)
- Affected sibling pair linkage analysis of qualitative and quantitative traits for schizophrenia on chromosome 22 in a Chinese population. (2001) (9)
- The KCNJ11 E23K Polymorphism and Progression of Glycaemia in Southern Chinese: A Long-Term Prospective Study (2011) (8)
- Clinicopathologic and gene expression parameters predict liver cancer prognosis (2011) (8)
- Recent developments in quantitative trait loci analysis (2003) (8)
- Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density (2018) (8)
- Schizophrenia and the androgen receptor gene: report of a sibship showing co-segregation with Reifenstein syndrome but no evidence for linkage in 23 multiply affected families. (1995) (8)
- The value of four mental health self-report scales in predicting interview-based mood and anxiety disorder diagnoses in sibling pairs. (2005) (8)
- Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders (2020) (8)
- Sharing of Genes and Pathways Across Complex Phenotypes: A Multilevel Genome-Wide Analysis (2017) (8)
- Inheritance of Neural Substrates for Motivation and Pleasure (2019) (8)
- The functional MMP-9 microsatellite marker is not associated with episodic memory in humans. (2008) (8)
- wKGGSeq: A Comprehensive Strategy‐Based and Disease‐Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders (2015) (8)
- Exome Sequencing and Gene Prioritization Correct Misdiagnosis in a Chinese Kindred with Familial Amyloid Polyneuropathy (2016) (8)
- Introduction to the Special Issue on Variance Components Methods for Mapping Quantitative Trait Loci (2004) (8)
- A powerful approach reveals numerous expression quantitative trait haplotypes in multiple tissues (2018) (8)
- The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study (2019) (7)
- Exome Sequencing Identifies a Novel Frameshift Mutation of MYO6 as the Cause of Autosomal Dominant Nonsyndromic Hearing Loss in a Chinese Family (2014) (7)
- Systemic neuro-dysregulation in depression: Evidence from genome-wide association (2020) (7)
- SNP-based HLA allele tagging, imputation and association with antiepileptic drug-induced cutaneous reactions in Hong Kong Han Chinese (2017) (7)
- De novo mutations in Caudal Type Homeo Box transcription Factor 2 (CDX2) in patients with persistent cloaca (2018) (7)
- Mendelian Randomization Focused Analysis of Vitamin D on the Secondary Prevention of Ischemic Stroke (2021) (7)
- HaploShare: identification of extended haplotypes shared by cases and evaluation against controls (2015) (7)
- A genetic variant in the gene encoding fibrinogen beta chain predicted development of hypertension in Chinese men (2010) (7)
- When GWAS meets the Connectivity Map: drug repositioning for seven psychiatric disorders (2016) (7)
- Associations between CLU polymorphisms and memory performance: The role of serum lipids in Alzheimer's disease. (2020) (6)
- Prevalence, psychosocial and physical health correlates of psychotic disorders in Hong Kong: the Hong Kong Mental Health Morbidity Survey (2015) (6)
- Sequential analysis and case-control candidate gene association studies: reply to Sobell et al. (1994) (6)
- surface antigen seroclearance in chronic hepatitis B (2013) (6)
- Types of gene–environment interplay and their statistical properties (2006) (6)
- Familial schizophrenia shows no gender difference in age of onset (1993) (6)
- Regression-Based Sib Pair Linkage Analysis for Binary Traits (2003) (6)
- D4 polymorphisms in schizophrenic patients treated with clozapine (1995) (6)
- Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma (2020) (6)
- Integrative analysis of metabolomic, genomic, and imaging-based phenotypes identify very-low-density lipoprotein as a potential risk factor for lumbar Modic changes (2021) (6)
- A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study (2022) (6)
- Clustering of SNP Data with Application to Genomics (2006) (6)
- A random forest-based framework for genotyping and accuracy assessment of copy number variations (2020) (6)
- MaGIC: a program to generate targeted marker sets for genome-wide association studies. (2004) (6)
- Computation of Individual Latent Variable Scores from Data with Multiple Missingness Patterns (2007) (6)
- Validation of single nucleotide polymorphism quantification in pooled DNA samples with SNaPIT™ (2002) (6)
- Biased cognition in East Asian and Western cultures (2019) (5)
- Genetic overlap between epilepsy and schizophrenia: Evidence from cross phenotype analysis in Hong Kong Chinese population (2018) (5)
- Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study (2021) (5)
- vSampler: fast and annotation-based matched variant sampling tool (2020) (5)
- Coagulation factors and COVID-19 severity: Mendelian randomization analyses and supporting evidence (2020) (5)
- Two-locus versus one-locus lods for complex traits. (1994) (5)
- Multifactorial disease risk calculator: Risk prediction for multifactorial disease pedigrees (2018) (5)
- LINE1 and Mecp2 methylation of the adult striatum and prefrontal cortex exposed to prenatal immune activation (2019) (5)
- Autoimmune diseases and psychosis: A case-control family study (1995) (5)
- Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait (2003) (5)
- Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines (2015) (5)
- iv) Genetics of disc degeneration (2008) (5)
- Assessing the statistical power to detect linkage in a sample of 51 bipolar affective disorder pedigrees (1996) (5)
- Is haplotype tagging the panacea to association mapping studies? (2004) (5)
- A Simple Bias Correction in Linear Regression for Quantitative Trait Association Under Two-Tail Extreme Selection (2011) (5)
- Extended gene set analysis of human neuro-psychiatric traits shows enrichment in brain-expressed human accelerated regions across development (2022) (5)
- Soluble interleukin 2 receptor levels in acute and stable schizophrenia (2001) (5)
- Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort. (2012) (5)
- Cerebellar hypoactivation is associated with impaired sensory integration in schizophrenia. (2020) (5)
- Title Association between promoter-1607 polymorphism of MMP 1 and lumbar disc disease in Southern Chinese (2008) (4)
- An Asian-specific MPL genetic variant alters JAK-STAT signaling and influences platelet count in the population. (2021) (4)
- Cost effective assay choice for rare disease study designs (2015) (4)
- Heritability of Serum Osteoprotegerin (2011) (4)
- On the Transformation of Genetic Effect Size from Logit to Liability Scale (2021) (4)
- The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis: findings from the EU-GEI study (2021) (4)
- The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs (2020) (4)
- Academic achievement at age 16 has contrasting effects on risk of later bipolar disorder and schizophrenia (2006) (4)
- Genetics of schizophrenia spectrum disorders: looking back and peering ahead. (2009) (4)
- SPS: A Simulation Tool for Calculating Power of Set‐Based Genetic Association Tests (2015) (4)
- Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases (2020) (4)
- Patient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis (2017) (4)
- 4 – Linkage Analysis Using Affected Sib-Pairs (1998) (4)
- Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus (2015) (4)
- Modeling Parent-Specific Genetic Nurture in Families with Missing Parental Genotypes: Application to Birthweight and BMI (2020) (4)
- Exposure to the Chinese Famine of 1959-1961 Rates of Adult Schizophrenia Following Prenatal (2005) (4)
- No NRG1 V266L in Chinese patients with schizophrenia (2011) (4)
- Agreement in the fluctuations of schizophrenia birth rates in Finland, Denmark, the Netherlands, Scotland, England and Wales (2002) (4)
- Polygenic scores without external summary statistics (2018) (4)
- Gene-by-environment Interaction in Twin and Sib-pair Analysis (2001) (3)
- Increased gene coverage and Alu frequency in large linkage disequilibrium blocks of the human genome. (2007) (3)
- Possible Modifying Effect of Hemoglobin A1c on Genetic Susceptibility to Severe Diabetic Retinopathy in Patients With Type 2 Diabetes (2020) (3)
- iCartiGD: the Integrated Cartilage Gene Database (2007) (3)
- Does familiality predispose to both emergence and persistence of psychosis? A prospective study (1996) (3)
- Polygenic scores using summary statistics via penalized regression (2016) (3)
- Unidimensional nonnegative scaling for genome-wide Linkage Disequilibrium maps (2008) (3)
- Test-retest reliability of ERP components of P300, P50, and duration mismatch negativity in monozygotic twins (2004) (3)
- Risky drinking by both sexes should be tackled (2002) (3)
- An ecological study of maternal and child nutritional supplementation and schizophrenia birth rates in England and Wales (2002) (3)
- Are psychiatric comorbidities and associated cognitive functions related to treatment response to methylphenidate in boys with attention-deficit/hyperactivity disorder? (2017) (3)
- (iii) Whole-genome association studies of complex diseases (2008) (3)
- Effects of pedigree structure and genetic model on the power of QTL linkage analysis. (2000) (3)
- studypsychotic bipolar disorder: Computational morphometry Regional volume deviations of brain structure in schizophrenia (2011) (3)
- Novel Sib Pair Selection Strategy Increases Power in Quantitative Association Analysis (2009) (3)
- Mutations in Hnrnpa 1 cause congenital heart defects (2018) (3)
- Cannabis-associated symptom profiles in patients with first episode psychosis and population controls (2019) (3)
- The Roles of PAX 6 and SOX 2 in Myopia : Lessons from the 1958 British Birth Cohort (2007) (3)
- Using common genetic variants to find drugs for common epilepsies (2021) (3)
- Effectiveness and optimal duration of early intervention treatment in adult-onset psychosis: a randomized clinical trial (2022) (3)
- Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy (2020) (3)
- Gender differences in age at onset in schizophrenia: A meta-analysis and meta-regression examining the effects of family history and study design (2004) (3)
- Statistical issues and approaches in endophenotype research (2011) (2)
- Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study. (2022) (2)
- Single-nucleotide polymorphisms near the microsatellite D17S1303 and the development of hypertension in a 6-year longitudinal study (2008) (2)
- Statistical Power and the Classical Twin Design (2020) (2)
- A family history study in British Afro-Carribean schizophrenic patients (1993) (2)
- SA117POLYGENIC RISK SCORE FOR PARKINSON DISORDER IS NEGATIVELY ASSOCIATED WITH PSYCHOTIC DISORDERS (2019) (2)
- DNA pooling, genome control and association studies. (2001) (2)
- Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development (2021) (2)
- 5.4 BIOLOGICAL AND EPIDEMIOLOGICAL EXAMINATION OF TRANSDIAGNOSTIC AND SPECIFIC SYMPTOM DIMENSIONS AT PSYCHOSIS ONSET: FINDINGS FROM THE EUGEI STUDY (2018) (2)
- Functional role of ICAM-3 polymorphism in genetic susceptibility to SARS infection. (2009) (2)
- Does prenatal exposure to influenza induce pyramidal cell disarray in mice? (1993) (2)
- Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity that may underly population disparities in this disease (2020) (2)
- Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in H (2010) (2)
- A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees (2005) (2)
- The Value of Four Mental Health Self-Report Scales in Predicting Interview-Based Mood and Anxiety Disorder Diagnoses in Sibling Pairs (2005) (2)
- The Application of Nof-1 Treatment Trials in Schizophrenia : A Systematic Review (2018) (2)
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (2)
- T42. JUMPING TO CONCLUSIONS IS ASSOCIATED WITH THE POLYGENIC RISK SCORE FOR INTELLIGENCE BUT NOT FOR SCHIZOPHRENIA. PRELIMINARY FINDINGS FROM THE EU-GEI STUDY (2019) (2)
- Disentangling Independent and Mediated Causal Relationships Between Blood Metabolites, Cognitive Factors, and Alzheimer’s Disease (2021) (2)
- Ameliorative patterns of grey matter in patients with first-episode and treatment-naïve schizophrenia. (2022) (2)
- Comparative genetic architectures of schizophrenia in East Asian and European populations (2019) (2)
- Genetics and population analysis WHAP: haplotype-based association analysis (2007) (2)
- A framework to decipher the genetic architecture of combinations of complex diseases: applications in cardiovascular medicine (2020) (2)
- Abnormal creases in the hand-prints of schizophrenic patients (1992) (2)
- 137 Evidence from a transmission/disequilibrium study that alleles of the DRB1*04 gene on chromosome 6p21.3 may protect against schizophrenia (1997) (2)
- A method for calculating probability convolution using “ternary” numbers with application in the determination of twin zygosity (1998) (2)
- Title Association of CDX 1 binding site of periostin gene with bonemineral density and vertebral fracture risk (2011) (2)
- SCHIZOPHRENIA AND INFLUENZA. REPLY (1991) (2)
- An autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping (2023) (2)
- (ii) Family-based linkage and case control association studies (2008) (2)
- Constrained unidimensional scaling with application to genomics (2007) (2)
- DESE: estimating driver tissues by selective expression of genes associated with complex diseases or traits (2019) (2)
- Uncovering complex disease subtypes by integrating clinical data and imputed transcriptome from genome-wide association studies: Applications in psychiatry and cardiovascular medicine (2019) (2)
- Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene (2022) (2)
- Polygenic power calculator: Statistical power and polygenic prediction accuracy of genome-wide association studies of complex traits (2022) (1)
- T110. FIRST EPISODE PSYCHOTIC PATIENTS WITH A HISTORY OF FREQUENT CANNABIS USE EXPRESS MORE POSITIVE SYMPTOMS AT ILLNESS ONSET THAN THOSE WHO NEVER USED CANNABIS (2018) (1)
- S77. JUMPING TO CONCLUSIONS AND FACIAL EMOTION RECOGNITION IMPAIRMENT IN FIRST EPISODE PSYCHOSIS ACROSS EUROPE (2018) (1)
- Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology (2022) (1)
- SU101. Altered Resting-State Functional Connectivity of Striatum in First-Episode Schizophrenia (2017) (1)
- Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti‐seizure medications (2022) (1)
- Power of OTL linkage and association analysis. (1999) (1)
- 235 Polymorphisms in the 5-HT2A receptor gene and promoter region associated with clozapine response (1997) (1)
- Simulation-based estimation of genetic, environmental and overall liability scores from pedigree affection data for multifactorial disorders (2004) (1)
- Author response: DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics (2020) (1)
- A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. (2001) (1)
- Concordance rates and biometrical model fitting for operational diagnoses in the maudsley twin psychosis series (1998) (1)
- GENOME-WIDE ASSOICATION STUDY OF ADOLESCENT IDIOPATHIC SCOLIOSIS IN SOUTHERN CHINA (2012) (1)
- Correction to: On the Transformation of Genetic Effect Size from Logit to Liability Scale (2021) (1)
- Inheritance of neural substrates for motivation and pleasure experience (2018) (1)
- Valproate Reverses Mania-Like Behavior of Clockdelta19 Mouse and Alters Monoamine Neurotransmitters Metabolism in the Hippocampus (2021) (1)
- GABA-A receptor subunit genes. An association analysis (1992) (1)
- Methods and resources to access mutation-dependent effects on cancer drug treatment (2019) (1)
- Title A diffusion tensor imaging study of structural dysconnectivity innever-medicated , first-episode schizophrenia (2008) (1)
- Correction: A Genome-Wide Linkage and Association Scan Reveals Novel Loci for Hypertension and Blood Pressure Traits (2012) (1)
- Reply to Faraway (1994) (1)
- DNA pooling analysis methods (2004) (1)
- KS-Burden: Assessing distributional differences of rare variants in dichotomous traits (2018) (1)
- The power of genome‐wide sib pair linkage scans for quantitative trait loci using the new Haseman–Elston regression method (2000) (1)
- Title Comparisons of seven algorithms for pathway analysis usingthe WTCCC Crohn ' s Disease dataset (2011) (1)
- Title HLAreporter : a tool for HLA typing from next generationsequencing data (2015) (1)
- DNA pooling identifies association of the noradrenergic transporter gene (NET1) with attention deficit hyperactivity disorder (ADHD). (2003) (1)
- Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals. (2021) (1)
- An association study of ADSS gene polymorphisms with schizophrenia (2008) (1)
- Clinical dimensions in schizophrenic families (2001) (1)
- Title MicroRNA-122 as a regulator of mitochondrial metabolic genenetwork in hepatocellular carcinoma (2010) (1)
- A twin study of clinical variables in psychotic disorders. (2000) (1)
- An overview of regression methods of linkage analysis in selected samples. (2001) (1)
- DNA pools on 10K genechips: Solving the QTL problem of large samples and large numbers of SNPS (2004) (1)
- Volumetric MRI study of brain structure in twins with schizophrenia (2002) (1)
- Molecular characterisation of ring chromosome 22. (2003) (1)
- Genome-wide DNA methylation data from adult brain following prenatal immune activation and dietary intervention (2019) (1)
- Selecting cases and controls for DNA sequencing studies using family histories of disease (2017) (1)
- Genome-wide Haplotype Association Mapping (HAM) in mice leads to an identification of a genetic variant in CER1 associated with bone mineral density in premenopausal women (2007) (1)
- Correction: C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism (2021) (1)
- First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of EU-GEI Data (2022) (1)
- Whole exome sequencing reveals a wide spectrum of ciliary gene mutations in nonsyndromic biliary atresia (2020) (1)
- Polygenic score analyses of schizophrenia and bipolar disorder with cardiometabolic traits (2016) (1)
- Book reviews : Neale MC, Cardon LR eds 1992: Methodology for genetic studies of twins and families. Dordrecht: Kluwer Academic Publishers BV. 496pp. £99.00. ISBN 0 7923 1874 9 (1993) (1)
- The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations. (2000) (1)
- The spatial proteome of the human intervertebral disc reveals architectural changes in health, ageing and degeneration (2020) (1)
- Linkage analysis on familial early-onset degenerative disc disease (2007) (1)
- Sense of Hyper-Positive Self Scale (2014) (1)
- SA46 THE GENETIC RISK UNDERLYING SYNAPSE PLASTICITY AND NEUROINFLAMMATION IN MAJOR DEPRESSIVE DISORDER (MDD): A JOINT WHOLE EXOME SEQUENCING (WES) AND STRUCTURAL MRI STUDY (2019) (1)
- Title Hedgehog / notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans (2011) (1)
- A generalised threshold defined case-control selection strategy for QTL association mapping in pooled DNA samples (2001) (1)
- 133. Interplay Between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-presentation Psychotic Disorder: A Pilot Study (2017) (1)
- Facial Emotion Recognition in Psychosis and Associations With Polygenic Risk for Schizophrenia: Findings From the Multi-Center EU-GEI Case–Control Study (2022) (1)
- A review and reanalysis of Bruno Schulz's “Erkrankungsalter schizophrener Eltern und Kinder [Age at onset of illness in schizophrenic parents and offspring]: “ Zeitschrift für die gesamte Neurologie und Psychiatrie, 168 709–721, 1940 (1995) (1)
- Genetic analysis of complex disease (1995) (1)
- Functional characterization of GWAS loci associated with fracture risk (2013) (0)
- HaploShare: identification of extended haplotypes shared by cases and evaluation against controls (2015) (0)
- eNOS haplotypes and risk of cerebral small vessel disease (2004) (0)
- Structural network alterations and their association with neurological soft signs in schizophrenia: Evidence from clinical patients and unaffected siblings (2021) (0)
- PO216 IMPACT OF DIABETIC RETINOPATHY GENETIC VARIANTS IDENTIFIED IN GENOME-WIDE ASSOCIATION STUDIES ON MICROVASCULAR COMPLICATIONS IN CHINESE PATIENTS WITH TYPE 2 DIABETES (2014) (0)
- Rare variants in sporadic Hirschsprung disease patients (2015) (0)
- NDT_A_293482 471..480 (2021) (0)
- Correction for Kwok et al., Genomic Diversity of Epstein-Barr Virus Genomes Isolated from Primary Nasopharyngeal Carcinoma Biopsy Samples (2014) (0)
- The genetic basis of cross-phenotype correlation with bone fracture risk: the GEFOS consortium (2013) (0)
- SNP-based HLA tagging, imputation, and association in adverse drug reaction of epilepsy patients from Hong Kong (2015) (0)
- Title Exome sequencing reveals a high genetic heterogeneity onfamilial Hirschsprung disease (2015) (0)
- Proteomics of mouse liver from embryo to adult: a lesion for HCC (2007) (0)
- Abstract 17603: Optimal Biomarkers for Predicting Incident Coronary Events in Patients With Established Coronary Artery Diseases (2016) (0)
- Pak Sham Statistics in Human Genetics ( International Relations and the Great Powers ) (0)
- Mendelian Inheritance and Segregation Analysis (2005) (0)
- Local True Discovery Rate Weighted Polygenic Scores Using GWAS Summary Data (2016) (0)
- Fine mapping of Hirschsprung’s disease loci in 9q31 (2009) (0)
- Genome-wide analysis identifies high-risk Epstein-Barr virus associated with nasopharyngeal carcinoma. (2018) (0)
- Title Exome-wide association analysis reveals novel codingsequence variants associated with lipid traits in Chinese (2015) (0)
- Neurological soft signs as endophenotype for schizophrenia: a link between genetics and clinical manifestations (2010) (0)
- Title Genetic overlap between bipolar illness and event-relatedpotentials (2007) (0)
- Genetics of Lumbar Disk Degeneration (2016) (0)
- Is Early Auditory Evoked Gamma Response a Heritable and Putative Endophenotype of Psychotic Bipolar Disorder (2009) (0)
- Uncovering bi-directional causal relationships between plasma proteins and psychiatric disorders: A proteome-wide study and directed network analysis (2019) (0)
- Genetic linkage analysis of early onset degenerative disc disease in Southern Chinese (2006) (0)
- Evaluating the predictive ability of polygenic risk scores from GWAS results (2016) (0)
- Title COGENT ( COlorectal cancer GENeTics ) : An international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2009) (0)
- Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes (2017) (0)
- Identification of ANXA2 as a Potential Susceptibility Gene for Diabetic Retinopathy in a Genome-Wide Association Analysis in Chinese Patients With Type 2 Diabetes Mellitus (2021) (0)
- In silico mapping of quantitative trait loci affecting bone mineral density in mice (2006) (0)
- Recent progress in genetic research on type 2 diabetes and obesity in East Asian populations (2016) (0)
- COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2010) (0)
- A review and reanalysis of Bruno Schulz`s "Age at onset of illness in schizophrenic parents and offspring. Z. Gesamte Neurol. Psychiatrie 168, 709-721 (1940)" (1995) (0)
- Title Predicting Mendelian Disease-Causing Non-Synonymous SingleNucleotide Variants in Exome Sequencing Studies (2013) (0)
- Relationship between volumetric structural abnormalities and white matter dysconnectivity in never-medicated patients with first-episode psychosis (2006) (0)
- Title HaploShare : identification of extended haplotypes shared bycases and evaluation against controls (2015) (0)
- Inaugural national scientific medical meeting (1993) (0)
- Inferring CTCF binding patterns and anchored loops across human tissues and cell types (2023) (0)
- Exome-chip association analyses for diabetic nephropathy and estimated glomerular filtration rate in Chinese patients with type 2 diabetes (2017) (0)
- A meta-analysis of association between the Ser9Gly polymorphism in the DRD3 gene and schizophrenia (2004) (0)
- Uncovering Resistant Genes in EGFR-mutated Lung Adenocarcinomas Prior to Targeted Therapy (2017) (0)
- Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation. (2023) (0)
- Shared genetic basis of schizophrenia and bipolar disorder with cardiometabolic traits (2016) (0)
- Regional multi-locus association models (2007) (0)
- Next-Generation Sequencing in Human Genetic Studies: Genome Technologies and Applications to Human Genetic Studies (2019) (0)
- Title A knowledge-based weighting framework to boost the power of genome-wide association studies (2010) (0)
- LIFELONG BURDEN OF VITAMIN D DEFICIENCY INCREASES CLINICAL CARDIAC EVENTS AND DEATH UNRAVELED BY AN EXOME CHIP-DERIVED MULTI-LOCI GENETIC RISK SCORE: A MENDELIAN-RANDOMIZED STUDY (2017) (0)
- Title Aerobic Exercise and Yoga Improve NeuroCognitive Function inWomen with Early Psychosis (2015) (0)
- Lack of association between TaqI A1 allele of dopamine D2 receptor gene and methamphetamine abuse or psychosis in Chinese (2001) (0)
- Dietary Intervention on the Epigenetic Changes Induced by Environmental Risk Factors in the Adolescent Brain (2014) (0)
- Prediction of lumbar spinal stenosis in Chinese: findings from a genome-wide association study (2013) (0)
- Impact of genetic variants identified in genome-wide association studies of diabetic retinopathy in Chinese patients with type 2 diabetes (2017) (0)
- F114THE DEVELOPMENT OF THE MAUDSLEY ENVIRONMENTAL RISK SCORE FOR PSYCHOSIS (2019) (0)
- SU108 ARE POLYGENIC RISK SCORES FOR MAJOR MENTAL DISORDERS ASSOCIATED WITH GENERAL OR SPECIFIC PSYCHOSIS SYMPTOM DIMENSIONS? (2019) (0)
- Sand and Gravel Resources of the Rocky Mountain House (West Three Quarters of 83B) and Calgary (North-Central of 82O Map Areas, AB) (1986) (0)
- Title dbPSHP : a database of recent positive selection across humanpopulations (2013) (0)
- An improved polygenic score for prediction in genome-wide association studies (2015) (0)
- A RET founder mutation in Chinese hirschsprung's patients (2009) (0)
- Mendelian randomization analysis of vitamin D in the secondary prevention of hypertensive-diabetic subjects: role of facilitating blood pressure control (2022) (0)
- Title iCartiGD : The Integrated Cartilage Gene Database (2007) (0)
- SU132CANNABIS USE AND SCHIZOPHRENIA: CAN GENETICS TELL IF IS IT ``THE CHICKEN OR THE EGG''? (2019) (0)
- Power of transmission/disequilibrium tests in admixed populations (2008) (0)
- Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice (2016) (0)
- Voxel-based analysis of diffusion tensor imaging in subjects with first-episode schiozphrenia (2004) (0)
- Trans-ethnic meta-analysis of Hirschsprung disease (2016) (0)
- Abstract 1921: Unraveling the genetic basis of nasopharyngeal carcinoma using next-generation sequencing approaches (2015) (0)
- LFMD: detecting low-frequency mutations in high-depth genome sequencing data without molecular tags (2019) (0)
- Extension of conditional model-free likelihood-based linkage analysis to additive and other models. (2002) (0)
- Replication study of genetic loci influencing age at menopause in Southern Chinese women (2015) (0)
- Improved nonparametric penalized maximum likelihood estimation for arbitrarily censored survival data (2022) (0)
- Association Between Monoamine Oxidase A Gene (CA)n Polymorphism and Risk for Schizophrenia in the Chinese Population (2004) (0)
- An association analysis of GABRB3, a candidate gene of the GABAA receptor complex on chromosome 15Q and autism spectrum disorder. [In Special Issue: XIII World Congress of Psychiatric Genetics 2005] (2005) (0)
- Transmission disequilibrium analysis of dopamine D3 and D4 receptors polymorphism (2004) (0)
- SamplesCarcinoma Biopsy Genomes Isolated from Primary Genomic Diversity of Epstein-Barr Virus (2014) (0)
- Erratum to: RET and NRG1 interplay in Hirschsprung disease (2014) (0)
- Allelic association between a ser-9-gly polymorphism in the D3 receptor gene and schizophrenia (1996) (0)
- Construction of Gene Regulatory Networks with Secondary Structures via Multi-task Sparse Group Lasso (2018) (0)
- Linkage disequilibrium mapping of chromosome 22 in schizophrenia using DNA pooling on Chinese and Scottish populations (1998) (0)
- cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes (2017) (0)
- Functional Pathways Participating In Myopia: Identification Through Genome-wide Association Studies (2011) (0)
- Clarifying the causes of consistent and inconsistent findings in genetics (2022) (0)
- Erratum to: RET and NRG1 interplay in Hirschsprung disease (2014) (0)
- Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese Short title: Adiponectin, SNP, and hypertension (2010) (0)
- Meta-analysis of genome-wide association studies of Hirschsprung disease in European and Asian populations (2012) (0)
- Linkage disequilibrium mapping of complex traits using SNP and microsatellite markers. (2000) (0)
- SA55. A Case–Control Study of Demographics and Clinical Predictors of Treatment-Resistant Schizophrenia in Patients 12 Years After First-Episode (2017) (0)
- Title A central resource for accurate allele frequency estimation frompooled DNA genotyped on DNA microarrays (2005) (0)
- Erratum: COGENT (COlorectal cancer GENeTics): An international consortium to study the role of polymorphic variation on the risk of colorectal cancer (British Journal of Cancer 102 (447-454) DOI: 10.1038/sj.bjc.6605338)) (2010) (0)
- Contents Vol. 69, 2014 (2014) (0)
- CENTRAL NERVOUS SYSTEM GENES TO THE DEVELOPMENT OF THE ENTERIC NERVOUS SYSTEM (2016) (0)
- Genetic epidemiology 1: behavioural genetics (2003) (0)
- Comments on Takei et al.: Prenatal exposure to influenza epidemics and the risk of mental retardation (2005) (0)
- A 1.36-megabase deletion in chromosome 18q21.32 including GRP in a patient with epilepsy, borderline intellectual disability, and multiple cerebral cavernous malformations (2015) (0)
- Spatial expression pattern of ZNF391 gene in the brains of patients with schizophrenia, bipolar disorders or major depressive disorder identifies new cross-disorder biotypes: A trans-diagnostic, top-down approach (2019) (0)
- AB113. The first genetic study on congenital choledochal dilatation (CCD) implicates extracellular matrix proteins (2015) (0)
- Title Improving polygenic risk prediction from summary statistics byan empirical Bayes approach (2017) (0)
- InterplaybetweenSchizophreniaPolygenic RiskScoreandChildhoodAdversityinFirst- PresentationPsychoticDisorder:APilotStudy (2016) (0)
- A sibling pair analysis of chronic fatigue and its relationship with mental health (2002) (0)
- Uncovering the genetic lesions underlying the most severe form of Hirschsprung disease by whole-genome sequencing (2018) (0)
- Single-Cell Transcriptome Sequencing Reveals Intra-Tumor Heterogeneity and Rare Stemness-Related Cell Subpopulation in Hepatocellular Carcinoma (2018) (0)
- SumVg: Total heritability explained by all variants in genome-wide association studies based on summary statistics with standard error estimates (2015) (0)
- SNP marker selection for association mapping of complex traits (2002) (0)
- Are the structural brain deviations associated with bipolar disorder related to susceptibility genes (2002) (0)
- Mutations in the NRG1 gene are associated with Hirschsprung disease (2011) (0)
- (OPCS)for 1939to 1960.As a measureof the prevalence of influenzaover time, weobtained the monthlynumbers of deathsattributedto influenzain Englandand Walesfrom 1938to 1960from the RegistrarGeneral'sAnnual Reviews (2006) (0)
- Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine (2017) (0)
- Title Whole exome sequencing coupled with unbiased functionalanalysis reveals new Hirschsprung disease genes (2017) (0)
- A powerful regression-based method of quantitative-trait linkage analysis for general pedigrees (2002) (0)
- Title Fine mapping of the NRG 1 hirschsprung ' s disease locus (2011) (0)
- Edinburgh Research Explorer Assessment of gene-by-sex interaction effect on bone mineral density (2018) (0)
- Genetic influences on metabolite levels in Alzheimer’s disease (2015) (0)
- Whole genome sequencing implicates rare variants in sporadic Hirschsprung disease (2017) (0)
- SA100 GABRB2 IS FUNCTIONALLY CONSERVED IN MOUSE AND MAN FOR ESSENTIAL NEURO-PSYCHOMOTOR ACTIVITIES (2019) (0)
- Brain structural endophenotypes of psychotic disorders and their association with genotypic variation (2004) (0)
- Genetic loci associated with age at menopause and bone mineral density in Southern Chinese women: a replication study (2019) (0)
- Poster #174 CAN PRENATAL SUPPLEMENTATION OF OMEGA-3 PREVENT THE EARLY PRODROME OF SCHIZOPHRENIA IN ADOLESCENCE IN A MOUSE MODEL? (2012) (0)
- M5 GENETIC OVERLAP BETWEEN ADHD AND ASD IN SHANK GENES IN CHINESE POPULATION (2019) (0)
- Title Chinese family with diffuse oesophageal leiomyomatosis : A newCOL 4 A 5 / COL 4 A 6 deletion and a case of gonosomal mosaicism (2015) (0)
- Patient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis (2017) (0)
- Title Polygenic scores using summary statistics via penalized regression Author list (2016) (0)
- Title Sacral agenesis : a pilot whole exome sequencing and copynumber study (2016) (0)
- S35INVESTIGATING THE ROLE OF MODIFIABLE RISK FACTORS ON THE CAUSAL PATHWAY TO ALZHEIMER'S DISEASE (2019) (0)
- Title Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22 q 11 . 21 as associated with systemic lupus erythematosus (2015) (0)
- Sand and Gravel Resources of the Peerless Lake (North Half of 84B) Map Area, Alberta (1986) (0)
- A cross-cultural comparison of the longitudinal heritability of childhood aggression (2016) (0)
- Title Patient complexity and genotype-phenotype correlations inbiliary atresia : a cross-sectional analysis (2017) (0)
- A causal association of ANKRD37 with human hippocampal volume. (2022) (0)
- Cytokines and schizophrenia revisited: a two-sample multi-marker Mendelian randomization approach (2019) (0)
- Identification of rare variants in the NRG1 gene of Hirschsprung's patients (2009) (0)
- Title Association of genetic variants in the adiponectin gene withadiponectin level and hypertension in Hong Kong Chinese (2010) (0)
- 128 Psychopathological dimensions and familial morbid risk of psychosis (1997) (0)
- Title Haplotype analysis reveals a possible founder effect of RET mutation R 114 H for Hirschsprung ' s disease in the Chinese population (2010) (0)
- Title Mutations in Hnrnpa 1 cause congenital heart defects (2018) (0)
- Whole Exome Sequencing versus Target Gene Panels for Evaluation of Isolated CaseProbands with Dilated and Hypertrophic Cardiomyopathy (2017) (0)
- LFMD: a new likelihood-based method to detect low-frequency mutations without molecular tags (2019) (0)
- Schizophrenia and psychotic bipolar disorder have distinct but overlapping brain structural phenotypes (2004) (0)
- Whole Exome Sequencing Identified a Novel Mutation in PMCA4 Gene for Autosomal Dominant Familial Spastic Paraplegia (ADFSP) in a Chinese Family (P2.060) (2014) (0)
- Common and rare variant associations with latent traits underlying depression, bipolar disorder, and schizophrenia (2023) (0)
- Genome-wide association study of Hirschsprung's disease (2007) (0)
- Sacral Agenesis: a Whole Exome Sequencing and Copy Number Study (2016) (0)
- Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls (2019) (0)
- Title Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection (2011) (0)
- Common Polymorphisms in the Low-Density Lipoprotein Receptor-Related Protein Are Associated With Refractive Error in the 1958 British Birth Cohort (2009) (0)
- Title Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia (2011) (0)
- Assessment of Aligner and SNP Caller for next generation sequencing and a fast and accurate SNP detection method (2013) (0)
- HLAreporter: a tool for HLA typing from next generation sequencing data (2015) (0)
- VKučinskas-2001-2016 (2016) (0)
- INSIDER: Interpretable Sparse Matrix Decomposition for Bulk RNA Expression Data Analysis (2022) (0)
- Linkage analysis of chromosome 1 markers in a sibling study of depression and anxiety (GENESIS) (2002) (0)
- Whole-exome sequencing identifies genetic susceptibility locus associated with familial nasopharyngeal carcinoma (2016) (0)
- The Use of Twins for QTL Mapping - Session: Statistical Issues in Twin Studies (2004) (0)
- Actionable secondary findings from whole-genome sequencing of 954 East Asians (2017) (0)
- Running title: Genetic variants and persistent central obesity (2010) (0)
- T158. NO ALTERATION OF PITUTARY VOLUME IN PATIENTS WITH FIRST-EPISODE SCHIZPHRENIA BUT A TREND OF ENLARGEMENT IN NON-PSYCHOTIC FIRST-DEGREE RELATIVES (2020) (0)
- Quantifying epistasis between two sets of signaling pathway genes by canonical correlation analysis (2009) (0)
- The dopamine transporter gene A quantitative trait locus for early hyperactivity (2002) (0)
- Identification of biomarkers for the prediction of HBV related HCC by integrated proteomics (2007) (0)
- Title European bone mineral density loci are also associated withBMD in East-Asian populations (2010) (0)
- The Contribution of Risk Factors to Blood Pressure Heritability Estimates in Young Adults: The East Flanders Prospective Twin Study (2004) (0)
- 1 TITLE : TTF-1 and RET promoter SNPs : regulation of RET transcription in Hirschsprung ' s disease (2004) (0)
- Obesity and metabolic syndrome Epidermal fatty-acid-binding protein : a new circulating biomarker associated with cardio-metabolic risk factors and carotid atherosclerosis (2008) (0)
- Accurate HLA Typing at High-Digit Resolution from NGS Data (2015) (0)
- One-year Outcome of a Specialised Early Intervention Treatment for Adult-onset Psychosis (JCEP): a Randomised Controlled Study (2012) (0)
- S76GENETIC VARIATION OF THE ENDOCANNABINOIDS SYSTEM AND RISK OF FIRST EPISODE PSYCHOSIS (2019) (0)
- The association between genetically elevated polyunsaturated fatty acids and risk of cancer (2023) (0)
- Explorer COGENT ( COlorectal cancer GENeTics ) : an international consortium to study the role of polymorphic variation on the risk of colorectal cancer (2017) (0)
- INCREASING ANCESTRY DIVERSITY IN PSYCHIATRIC GENOMICS RESEARCH (2019) (0)
- A Functional Missense Variant of the Glucokinase Regulator Gene (GCKR) Is Associated with Raised FGF21 Levels in an Exome-Chip Association Study Amongst Chinese Individuals (2017) (0)
- Genome-wide association study identifies susceptibility loci for biliary atresia (2008) (0)
- Fine mapping on chromosome 10q24.2 implicates ADD3 in biliary atresia (2012) (0)
- F88DETECTING AND CONTROLLING FOR BIASED SAMPLING IN CASE/CONTROL PRS STUDIES (2019) (0)
- AB080. Genetic findings provide insight of biliary atresia patient complexity (2015) (0)
- Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease (2022) (0)
- T52. COGNITION, METACOGNITION AND SOCIAL COGNITION AFTER A FIRST EPISODE PSYCHOSIS. PRELIMINARY RESULTS FROM A 5-YEAR-FOLLOW-UP STUDY (2020) (0)
- Title CFTR founder mutation causes protein trafficking defects inChinese patients with cystic fibrosis (2016) (0)
- Selecting maximally informative sibships for OTL association analysis. (1999) (0)
- Genome-wide gene-set analysis identifies different patterns of genetic sharing across complex phenotypes (2015) (0)
- Genetic Contribution to Degeneration and Repair Potentials of the Intervertebral Disc in Mice (2016) (0)
- T230. Polygenic Risk Score Increases Schizophrenia Liability Through Cognition-Relevant Pathways: Causal Modelling With Latent Cognition and Polygenic Risk (2018) (0)
- A comprehensive database for GWAS¬identified human genetic variants: an update of GWASdb (2015) (0)
- Exome-chip association analysis on a multifunctional anti-tumor factor, pigment epithelium-derived factor (PEDF), in patients with type 2 diabetes (2018) (0)
- Knowledge-based genetic association study of hepatitis B virus related hepatocellular carcinoma (2019) (0)
- Title Frontal-subcortical protein expression following prenatalexposure to maternal inflammation (2011) (0)
- Modelling Feasibility of Genetic Approaches to Human Stroke (2001) (0)
- O4.8. CAN YOU SPOT EMOTIONS? FACIAL EMOTION RECOGNITION AND GENETIC RISK FOR PSYCHOSIS (2019) (0)
- Title Mri study of minor physical anomaly in childhood autismimplicates aberrant neurodevelopment in infancy (2011) (0)
- Polymorphisms in the serotonin transporter, MAOA and COMT genes and susceptibility to unipolar depression (2004) (0)
- Cognitive style and personality in euthymic patients with bipolar disorder (2004) (0)
- Title CLUSTAG : Hierarchical clustering and graph methods forselecting tag SNPs (2005) (0)
- Intellectual asymmetry and genetic liability Intellectual asymmetry and genetic liability in first-degree relatives of probands in first-degree relatives of probands with schizophrenia with schizophrenia (2004) (0)
- An index of multipoint polymorphism information content (MPIC). (2001) (0)
- Linkage disequilibrium mapping of chromosome 8, 13 and 22 linkage regions in schizophrenia using DNA pooling on Chinese and Scottish populations (1999) (0)
- Genetics and population analysis IGG 3 : a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis (2009) (0)
- Title Identification of genes with allelic imbalance on 6 p associatedwith nasopharyngeal carcinoma in Southern Chinese (2011) (0)
- Candidate transmission disequilibrium analysis for quantitative traits in tourette syndrome in a chinese family trio sample (2000) (0)
- Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study (2015) (0)
- Estimating driver-tissues by robust selective expression of genes associated with complex diseases or traits (2018) (0)
- Use of DNA pooling in large-scale association studies (2004) (0)
- Using next-generation whole-exome sequencing approaches to elucidate the genetic basis for nasopharyngeal carcinoma (2014) (0)
- F115POLYGENIC RISK SCORES FOR SCHIZOPHRENIA, BIPOLAR, AND MAJOR DEPRESSIVE DISORDERS PREDICT TRANSDIAGNOSTIC SYMPTOM DIMENSIONS AT FIRST EPISODE PSYCHOSIS (2019) (0)
- Dissecting the Genetic and Environmental Relationship between Schizophrenia and Duration MMN (2009) (0)
- Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes (2016) (0)
- Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma (2020) (0)
- 127 Affective illness in the mother as a risk factor for obstetric complications (1997) (0)
- THE EFFECT OF INCREASINGLY STRINGENT DIAGNOSTIC CRITERIA ON SEX DIFFERENCES IN SCHIZOPHRENIA (1999) (0)
- Single-subject fMRI analysis on a response inhibition task which is pertinent to the study of impulsivity in attention-deficit-hyperactivity disorder (ADHD) (2004) (0)
- A Bayesian network-based framework to uncover the causal effects of genes on complex traits based on GWAS data (2022) (0)
- Proteomic expression clustering of mouse liver developmental stages (2006) (0)
- Title Autistic disorders and schizophrenia : Related or remote ? Ananatomical likelihood estimation (2010) (0)
- Improved Non-parametric Penalized Maximum Likelihood Estimation for Arbitrarily Censored Survival Data (2021) (0)
- RET and NRG1 interplay in Hirschsprung disease (2013) (0)
- Genetic variants on NRG1 confer susceptibility to Hirschsprung's disease (2008) (0)
- Title PMCA 4 ( ATP 2 B 4 ) mutation in familial spastic paraplegia causesdelay in intracellular calcium extrusion (2014) (0)
- Genetic Studies in Affective Disorders: Overview of Methods, Current Directions and Critical Research Issues . Edited by D. F. Papolos and H. M. Lachman. (Pp. 236; £32.95.) John Wiley & Sons: Chichester. 1994. (1995) (0)
- Use of multiple Polygenic Risk Scores for distinguishing Schizophrenia-spectrum disorder and Affective psychosis categories; the EUGEI study (2021) (0)
- Title Association of ICAM 3 genetic variant with severe acuterespiratory syndrome (2007) (0)
- Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan® arrays (2013) (0)
- Fine mapping candidate loci for nasopharyngeal carcinoma (NPC) in southern Chinese specifically linked to EBV aetiopathogenesis (2010) (0)
- Title Association of the Asporin D 14 Allele with Lumbar-DiscDegeneration in Asians (0)
- Essential Psychiatry: Genetic epidemiology (2008) (0)
- Can investigations of brain function help characterize the prodrome (2004) (0)
- Commingling of Optic Disc Parameters in an Older Australian Population (2006) (0)
- Altered protein expression of rat prefrontal cortex following perinatal asphyxia: implications of schizophrenia and autism (2013) (0)
- Title Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy (2018) (0)
- Abstract 17620: Incremental Values of Biomarkers for Predicting Incident Peripheral Vascular Disease Events in Patients With Established Coronary Artery Diseases (2016) (0)
- Genetics of congenital megacolon in East Asians (2018) (0)
- 816 Alterations of Human Gastric Microbiota in Patients With H. pylori Infection and Different Stages of Gastric Carcinogenesis (2015) (0)
- PAX6 and SOX2 Are Not Associated With Myopia: Findings From the 1958 British Birth Cohort (2007) (0)
- Prenatal immune challenge causes frontal-subcortical proteome changes relevant to schizophrenia and autism (2010) (0)
- The effects of maternal SSRI exposure on the serotonin system, prefrontal protein expression and behavioral development in male and female offspring rats (2020) (0)
- C-reactive protein as a predictor of hypertension in the Hong Kong Cardiovascular Risk Factor Preval (2011) (0)
- Justification and techniques for gene-based association analysis (2004) (0)
- SU109IS THE ERA OF CANDIDATE GENES X CANNABIS USE REALLY DEAD? (2019) (0)
- Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (0)
- Validation of association signals identified from genome-wide association studies of diabetic retinopathy in Chinese patients with type 2 diabetes (2018) (0)
- The role of gene variants in the pathogenesis of neurodegenerative disorders as revealed by next generation sequencing studies: a review (2017) (0)
- 63THE EFFECT, DETECTION AND ADJUSTMENT OF SAMPLE OVERLAP IN PRS STUDIES (2019) (0)
- Mendelian randomization analysis of vitamin D in the secondary prevention of hypertensive-diabetic subjects: role of facilitating blood pressure control (2022) (0)
- Discovering the structure and organization of a free Cantonese emotion-label word association graph to understand mental lexicons of emotions (2022) (0)
- The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study. (2023) (0)
- SU112DOES POLYGENIC RISK SCORE FOR SCHIZOPHRENIA IMPACT ON JUMPING TO CONCLUSIONS? PRELIMINARY FINDINGS FROM THE EU-GEI CASE-CONTROL STUDY (2019) (0)
- Poster #19 X-LINKED TSPYI2DEFICIT MOUSE IS ASSOCIATED WITH A PHENOTYPE OF SCHIZOPHRENIA (2012) (0)
- Title A comprehensive framework for prioritizing variants in exomesequencing studies of Mendelian diseases (2012) (0)
- Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study. (2023) (0)
- Chemotherapy-Induced Cognitive Impairment Is Associated with Cytokine Dysregulation and Disruptions in Neuroplasticity (2018) (0)
- SA59POLYGENIC RISK SCORE INCREASES SCHIZOPHRENIA LIABILITY THROUGH COGNITION-RELEVANT PATHWAYS (2019) (0)
- Evidence of genomic imprinting in families with Gilles de la Tourette syndrome in Chinese subjects (2001) (0)
- Third-generation genome sequencing implicates medium-sized structural variants in chronic schizophrenia (2023) (0)
- Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data (2021) (0)
- Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk. (2023) (0)
- Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy (2018) (0)
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