Pål Nyrén
#34,705
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Swedish professor of biochemistry
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Pål Nyrénbiology Degrees
Biology
#1900
World Rank
#3077
Historical Rank
Biochemistry
#621
World Rank
#715
Historical Rank
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Biology
Pål Nyrén's Degrees
- PhD Biochemistry Stockholm University
Why Is Pål Nyrén Influential?
(Suggest an Edit or Addition)According to Wikipedia, Pål Nyrén is a biochemistry professor at the Royal Institute of Technology , Stockholm. He is most famous for developing the pyrosequencing method for DNA sequencing. Career 1999 Professor in Biochemistry, KTH, Stockholm1997 Founder of the company Biotage AB 1988 Associate professor Biochemistry, University of Stockholm1985-86 Postdoc at LMB, MRC, Cambridge, G.B. with prof John Walker1985 PhD Biochemistry, University of Stockholm 1981 MSc Chemical Engineering, KTH, Stockholm
Pål Nyrén's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Sequencing Method Based on Real-Time Pyrophosphate (1998) (1691)
- Real-time DNA sequencing using detection of pyrophosphate release. (1996) (1220)
- Comparative Analysis of Human Gut Microbiota by Barcoded Pyrosequencing (2008) (954)
- Single-nucleotide polymorphism analysis by pyrosequencing. (2000) (450)
- Sequence of the bovine mitochondrial phosphate carrier protein: structural relationship to ADP/ATP translocase and the brown fat mitochondria uncoupling protein. (1987) (201)
- Enzymatic method for continuous monitoring of inorganic pyrophosphate synthesis. (1985) (187)
- Solid phase DNA minisequencing by an enzymatic luminometric inorganic pyrophosphate detection assay. (1993) (186)
- Enzymatic method for continuous monitoring of DNA polymerase activity. (1987) (161)
- The history of pyrosequencing. (2007) (108)
- Mutation detection by pyrosequencing: sequencing of exons 5-8 of the p53 tumor suppressor gene. (2000) (102)
- Analyses of secondary structures in DNA by pyrosequencing. (1999) (100)
- Long-read pyrosequencing using pure 2'-deoxyadenosine-5'-O'-(1-thiotriphosphate) Sp-isomer. (2002) (98)
- Typing of Human Papillomavirus by Pyrosequencing (2001) (97)
- Whole-genome sequencing of the efficient industrial fuel-ethanol fermentative Saccharomyces cerevisiae strain CAT-1 (2012) (71)
- Identification of medically important fungi by the PyrosequencingTM technology (2004) (70)
- Method enabling pyrosequencing on double-stranded DNA. (2000) (69)
- Proton-pumping N,N'-dicyclohexylcarbodiimide-sensitive inorganic pyrophosphate synthase from Rhodospirillum rubrum: purification, characterization, and reconstitution. (1991) (67)
- Detection of single-base changes using a bioluminometric primer extension assay. (1997) (61)
- Type-specific multiple sequencing primers: a novel strategy for reliable and rapid genotyping of human papillomaviruses by pyrosequencing technology. (2005) (61)
- Analysis of the p53 tumor suppressor gene by pyrosequencing. (2000) (56)
- PCR-introduced loop structure as primer in DNA sequencing. (1998) (53)
- Connector Inversion Probe Technology: A Powerful One-Primer Multiplex DNA Amplification System for Numerous Scientific Applications (2007) (45)
- Methodological improvements of pyrosequencing technology. (2006) (39)
- Multiple‐primer DNA sequencing method (2003) (38)
- Viral and microbial genotyping by a combination of multiplex competitive hybridization and specific extension followed by hybridization to generic tag arrays. (2003) (37)
- Studies on photosynthetic inorganic pyrophosphate formation in Rhodospirillum rubrum chromatophores. (1986) (35)
- Reconstitution of highly purified proton‐translocating pyrophosphatase from Rhodospirillum rubrum (1982) (34)
- Production, Purification, and Luminometric Analysis of RecombinantSaccharomyces cerevisiae MET3Adenosine Triphosphate Sulfurylase Expressed inEscherichia coli (1999) (34)
- Method enabling fast partial sequencing of cDNA clones. (2001) (33)
- Hypothesis: the physiological role of the membrane‐bound proton‐translocating pyrophosphatase in some phototrophic bacteria (1991) (33)
- Method for real-time detection of inorganic pyrophosphatase activity. (2001) (31)
- Immunological cross-reactivity between proton-pumping inorganic pyrophosphatases of widely phylogenic separated species. (1991) (30)
- PathogenMip Assay: A Multiplex Pathogen Detection Assay (2007) (29)
- Purification of the membrane-bound proton-translocating inorganic pyrophosphatase from Rhodospirillum rubrum (1984) (27)
- Method enabling firefly luciferase-based bioluminometric assays at elevated temperatures. (2003) (24)
- Detection of gyrA mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by rapid and reliable pre-programmed short DNA sequencing. (2005) (23)
- Multiple group-specific sequencing primers for reliable and rapid DNA sequencing. (2003) (22)
- Sentinel-base DNA genotyping using multiple sequencing primers for high-risk human papillomaviruses. (2006) (22)
- Improvements in Pyrosequencing technology by employing Sequenase polymerase. (2004) (22)
- DNA gyrase gene in Neisseria gonorrhoeae as indicator for resistance to ciprofloxacin and species verification (2005) (21)
- Method for one-step preparation of double-stranded DNA template applicable for use with Pyrosequencing technology. (2002) (20)
- Methylotrophic yeast Pichia pastoris as a host for production of ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum). (2003) (20)
- Apyrase immobilized on paramagnetic beads used to improve detection limits in bioluminometric ATP monitoring. (1994) (17)
- Human papillomavirus (HPV), DNA aberrations and cell cycle progression in anal squamous cell carcinoma patients. (2007) (17)
- Quantification of HIV-1 using multiple quantitative polymerase chain reaction standards and bioluminometric detection. (2001) (17)
- Real-time bioluminometric method for detection of nucleoside diphosphate kinase activity. (1999) (16)
- Real-time detection and quantification of adenosine triphosphate sulfurylase activity by a bioluminometric approach. (1999) (15)
- Production, purification, and luminometric analysis of recombinant Saccharomyces cerevisiae MET3 adenosine triphosphate sulfurylase expressed in Escherichia coli. (1999) (15)
- Chapter 6 The synthesis and utilization of inorganic pyrophosphate (1984) (14)
- Method for clone checking (2003) (14)
- Diethylstilbestrol. Interactions with membranes and proteins and the different effects upon Ca2+- and Mg2+-dependent activities of the F1-ATPase from Rhodospirillum rubrum. (1988) (13)
- The History of Pyrosequencing(®). (2015) (12)
- Collinearity of protease mutations in HIV-1 samples with high-level protease inhibitor class resistance (2012) (12)
- A mathematical model of the Pyrosequencing reaction system. (2004) (12)
- Synthesis of pyrophosphate coupled to the reverse energy‐linked transhydrogenase reaction in Rhodospirillum rubrum chromatophores (1986) (12)
- 7‐Deaza‐2′‐Deoxyadenosine‐5′‐Triphosphate as an Alternative Nucleotide for the Pyrosequencing Technology (2004) (11)
- Conversion of coupling factor 1 of Rhodospirillum rubrum from a Ca2+-ATPase into a Mg2+-ATPase. (1988) (11)
- Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis. (2003) (11)
- A 3-hydroxy-3-methylglutaryl-CoA lyase gene in the photosynthetic bacterium Rhodospirillum rubrum. (1997) (10)
- Diethylstilbestrol is a potent inhibitor of the H (+) (-)PPase but not of the H (+) (-)ATPase of Rhodospirillum rubrum chromatophores. (1987) (10)
- Pyrosequencing Technology for Short DNA Sequencing and Whole Genome Sequencing (2007) (9)
- The effect of equisetin on energy-linked reactions in Rhodospirillum rubrum chromatophores. (1989) (8)
- Pyrosequencing™ technology at elevated temperature (2004) (8)
- Photosynthetic formation of inorganic pyrophosphate in phototrophic bacteria (1990) (8)
- Amino acid sequence similarities between the vacuolar proton-pumping inorganic pyrophosphatase and the c-subunit of F0F1-ATPases. (1993) (8)
- Improvement in cell capture throughput using parallel bioactivated microfluidic channels (2012) (8)
- Inorganic pyrophosphatase-based detection systems. II. Detection and quantification of cell lysis and cell-lysing activity. (1994) (8)
- Division of divalent cations into two groups in relation to their effect on the coupling of the F0F1-ATPase of Rhodospirillum rubrum to the protonmotive force. (1989) (7)
- Kinetics of the membrane‐bound inorganic pyrophosphatase from Rhodospirillum rubrum chromatophores (1986) (7)
- Amount and turnover rate of the F0F1-ATPase and the stoichiometry of its inhibition by oligomycin in Rhodospirillum rubrum chromatophores. (1989) (7)
- A sensitive and rapid method for determination of pyrophosphatase activity. (1982) (7)
- Inorganic pyrophosphatase-based detection systems. I. Detection and enumeration of cells. (1994) (6)
- [54] Preparation and reconstitution of the proton-pumping membrane-bound inorganic pyrophosphatase from Rhodospirillum rubrum (1986) (6)
- Bioluminometric method for real-time detection of reverse transcriptase activity. (1998) (6)
- Toward pyrosequencing on surface-attached genetic material by use of DNA-binding luciferase fusion proteins. (2004) (5)
- A method for sequencing DNA (1997) (4)
- Some characteristics of cyclic photophosphorylation in maize bundle sheath chloroplasts. (1988) (3)
- Quinolone-resistant Neisseria gonorrhoeae – response (2005) (2)
- Single-nucleotide polymorphisms in the B7H3 gene are not associated with human autoimmune myasthenia gravis. (2006) (2)
- Determination of the Intracellular Concentration of Inorganic Pyrophosphate in Rhodospirillum rubrum (1990) (1)
- Membrane-bound inorganic pyrophosphatase. (1984) (1)
- Single-nucleotide polymorphisms in theB7H3 gene are not associated with human autoimmune myasthenia gravis (2006) (1)
- Some basic properties of photosynthetic energy coupling (1985) (1)
- Some Similarities and Differences between Bacterial Chromatophore, Spinach Chloroplast and Yeast Mitochondrial Inorganic Pyrophosphatases (1990) (0)
- F1-ATPase from Rhodopseudomonas blastica. (1989) (0)
- FoF1-ATPase Content in Chromatophores of Rhodospirillum rubrum and Stoichiometry of Oligomycin Binding (1990) (0)
- Improvement in cell capture throughput using parallel bioactivated microfluidic channels (2012) (0)
- Inorganic Pyrophosphate in Cellular Energetics and Evolution (1988) (0)
- An Investigation of the Apyrase Stepin the Pyrosequencing Model:Combining Experiments and Simulations. (2005) (0)
- Intrinsic Uncoupling of the FoF1-ATPase Dependent on what Divalent Cation is Used (1990) (0)
- Purification and Reconstitution of the Proton Translocating Membrane Bound Inorganic Pyrophosphatase from Rhodospirillum rubrum (1986) (0)
- Amino acid sequence similarities [of Arabidopsis thaliana and Rhodospirillum rubrum] between the vacuolar proton-pumping inorganic pyrophosphatase and the c-subunit of F0F1-ATPases (1993) (0)
- Towards an Improved Polymerase Descriptionin the Pyrosequencing Model. (2005) (0)
- The Purified F1-ATPase of Rhodopseudomonas blastica is a Ca++ -ATPase (1990) (0)
- LIGHT-DRIVEN INORGANIC PYROPHOSPHATE SYNTHESIS IN PHOTOTROPHIC BACTERIA (1990) (0)
- Method enabling detection of single-stranded DNA ligation activity. (2017) (0)
- Whole-genome sequencing of the efficient industrial fuel-ethanol fermentative Saccharomyces cerevisiae strain CAT-1 (2012) (0)
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