Pamela J. Bjorkman
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American biochemist
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Biology
Pamela J. Bjorkman's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Biochemistry University of California, Davis
Why Is Pamela J. Bjorkman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Pamela Jane Bjorkman NAS, AAAS is an American biochemist. She is the David Baltimore Professor of Biology and Biological Engineering at the California Institute of Technology , Her research centers on the study of the three-dimensional structures of proteins related to Class I MHC, or Major Histocompatibility Complex, proteins of the immune system and proteins involved in the immune responses to viruses . Bjorkman is most well known as a pioneer in the field of structural biology.
Pamela J. Bjorkman's Published Works
Published Works
- Structure of the human class I histocompatibility antigen, HLA-A2 (1987) (3124)
- T-cell antigen receptor genes and T-cell recognition (1988) (2558)
- The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens (1987) (2338)
- Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals (2020) (1577)
- Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution. (1991) (1094)
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding (2011) (1073)
- SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies (2020) (1014)
- The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. (1998) (852)
- A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules (1988) (840)
- mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants (2021) (831)
- Structure, function, and diversity of class I major histocompatibility complex molecules. (1990) (703)
- Evolution of antibody immunity to SARS-CoV-2 (2021) (703)
- Evolution of Antibody Immunity to SARS-CoV-2 (2020) (680)
- Specificity pockets for the side chains of peptide antigens in HLA-Aw68 (1990) (662)
- mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants (2021) (621)
- Crystal Structure of the Hemochromatosis Protein HFE and Characterization of Its Interaction with Transferrin Receptor (1998) (613)
- Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies (2012) (499)
- HIV therapy by a combination of broadly neutralizing antibodies in humanized mice (2012) (493)
- Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization (2013) (474)
- T-cell antigen receptor genes and T-cell recognition (1988) (468)
- Crystal structure of the complex of rat neonatal Fc receptor with Fc (1994) (435)
- Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies (2020) (418)
- The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18. (1999) (396)
- Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies (2020) (394)
- Phenotypic properties of transmitted founder HIV-1 (2013) (389)
- Structure of the human class I histocompatibility antigen, HLA-A2. (2005) (377)
- Binding and uptake of H-ferritin are mediated by human transferrin receptor-1 (2010) (376)
- Gut microbiota utilize immunoglobulin A for mucosal colonization (2018) (374)
- Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design (2011) (373)
- Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. (1999) (366)
- HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption (2016) (362)
- Antibody 10-1074 suppresses viremia in HIV-1-infected individuals (2017) (354)
- Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding. (2001) (348)
- The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. (2008) (330)
- Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy (2014) (325)
- Combination therapy with anti-HIV-1 antibodies maintains viral suppression (2018) (324)
- Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor (2000) (324)
- Fc receptors and their interactions with immunoglobulins. (1996) (322)
- Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor (1994) (312)
- Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants. (1995) (300)
- Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques (2014) (297)
- Crystal structure of invasin: a bacterial integrin-binding protein. (1999) (279)
- Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors (2015) (260)
- HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1 (2016) (257)
- Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor (2003) (256)
- Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico (2017) (255)
- HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice (2013) (255)
- Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc (2003) (248)
- Comparison of the Interactions of Transferrin Receptor and Transferrin Receptor 2 with Transferrin and the Hereditary Hemochromatosis Protein HFE* (2000) (248)
- Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,). (2000) (248)
- Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice (2015) (242)
- Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies (2021) (239)
- Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice (2021) (233)
- Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase (2005) (233)
- Few and Far Between: How HIV May Be Evading Antibody Avidity (2010) (228)
- Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. (2014) (215)
- Modulation of Natural Killer Cell Cytotoxicity in Human Cytomegalovirus Infection: The Role of Endogenous Class I Major Histocompatibility Complex and a Viral Class I Homolog (1998) (215)
- Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120 (2012) (206)
- Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping (2015) (200)
- The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor. (1999) (183)
- Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site (2016) (182)
- Crystal structure of hemolin: a horseshoe shape with implications for homophilic adhesion. (1998) (181)
- Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations (2021) (170)
- FcRn-mediated antibody transport across epithelial cells revealed by electron tomography (2008) (158)
- Interaction of Hemojuvelin with Neogenin Results in Iron Accumulation in Human Embryonic Kidney 293 Cells* (2005) (154)
- Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10 (2009) (151)
- The MHC class I homolog encoded by human cytomegalovirus binds endogenous peptides. (1995) (149)
- Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals (2020) (148)
- Structural basis of pH-dependent antibody binding by the neonatal Fc receptor. (1998) (147)
- Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand. (1994) (147)
- Thermal stability comparison of purified empty and peptide-filled forms of a class I MHC molecule. (1992) (144)
- Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection (2015) (144)
- Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2). (2000) (143)
- A linear lattice model for polyglutamine in CAG-expansion diseases (2002) (141)
- Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules. (1999) (138)
- Climate change and the integrity of science. (2010) (137)
- Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60. (2001) (134)
- The chicken yolk sac IgY receptor, a functional equivalent of the mammalian MHC-related Fc receptor, is a phospholipase A2 receptor homolog. (2004) (133)
- HFE and Transferrin Directly Compete for Transferrin Receptor in Solution and at the Cell Surface* (2004) (133)
- Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env (2015) (129)
- Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites. (2001) (127)
- Structural characterization of anti-inflammatory immunoglobulin G Fc proteins. (2014) (126)
- Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller (2017) (125)
- De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2 (2020) (123)
- Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand (2000) (121)
- LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells (2017) (119)
- Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity (2010) (114)
- Crystal structure of tandem type III fiibronectin domains from drosophila neuroglian at 2.0 å (1994) (114)
- Mechanism for Multiple Ligand Recognition by the Human Transferrin Receptor (2003) (113)
- Computational analysis of anti–HIV-1 antibody neutralization panel data to identify potential functional epitope residues (2013) (111)
- Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop (2016) (109)
- The (Greek) Key to Structures of Neural Adhesion Molecules (1996) (104)
- Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis (2019) (104)
- Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1 (2015) (103)
- Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae (2005) (102)
- MHC Restriction in Three Dimensions: A View of T Cell Receptor/Ligand Interactions (1997) (102)
- The class I major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release. (1993) (101)
- Investigation of the biophysical and cell biological properties of ferroportin, a multipass integral membrane protein iron exporter. (2009) (97)
- Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging (2006) (97)
- CATNAP: a tool to compile, analyze and tally neutralizing antibody panels (2015) (96)
- Crystal structure of a polymeric immunoglobulin binding fragment of the human polymeric immunoglobulin receptor. (2004) (96)
- Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms (2021) (92)
- Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules. (1992) (92)
- Design and characterization of structured protein linkers with differing flexibilities (2014) (92)
- Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies (2013) (90)
- Bivalent binding of IgA1 to FcalphaRI suggests a mechanism for cytokine activation of IgA phagocytosis. (2003) (90)
- Identification of critical IgG binding epitopes on the neonatal Fc receptor. (1997) (88)
- Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor (2006) (88)
- Investigate the origins of COVID-19 (2021) (88)
- Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution. (1999) (88)
- Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor (2008) (85)
- The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis. (1999) (84)
- Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants (2014) (82)
- Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains. (2005) (81)
- The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model (2007) (80)
- HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. (2018) (80)
- A gut-derived metabolite alters brain activity and anxiety behaviour in mice (2022) (79)
- Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice (2021) (75)
- Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope (2018) (75)
- Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques (2019) (74)
- Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc. (1993) (74)
- High-affinity binding of the neonatal Fc receptor to its IgG ligand requires receptor immobilization. (1997) (73)
- Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog (1998) (72)
- Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody (2020) (72)
- A mouse model for HIV-1 entry (2012) (71)
- Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy (2021) (71)
- Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport (2011) (69)
- Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope (2019) (69)
- Stoichiometry of the interaction between the major histocompatibility complex-related Fc receptor and its Fc ligand. (1999) (68)
- Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York (2021) (68)
- Structural basis for germline antibody recognition of HIV-1 immunogens (2016) (66)
- Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. (2018) (66)
- Intractable COVID-19 and Prolonged SARS-CoV-2 Replication in a CAR-T-cell Therapy Recipient: A Case Study. (2021) (66)
- A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies (2015) (65)
- Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion (2018) (65)
- Crystallization and X-ray diffraction studies on the histocompatibility antigens HLA-A2 and HLA-A28 from human cell membranes. (1985) (63)
- FcRn mediates elongated serum half-life of human IgG in cattle. (2006) (63)
- Crystal structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18 (2002) (62)
- Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan (2001) (62)
- The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins (2016) (62)
- Peptidoglycan Production by an Insect-Bacterial Mosaic (2019) (60)
- The chicken yolk sac IgY receptor, a mammalian mannose receptor family member, transcytoses IgY across polarized epithelial cells. (2008) (60)
- Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody (2013) (59)
- Biochemical characterization and crystalization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homolog. (1997) (58)
- Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy (2021) (57)
- B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV (2021) (57)
- SARS-CoV-2 Viremia is Associated with COVID-19 Severity and Predicts Clinical Outcomes. (2021) (56)
- Hydrophobic Ligand Binding by Zn-α2-glycoprotein, a Soluble Fat-depleting Factor Related to Major Histocompatibility Complex Proteins* (2001) (56)
- Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains. (2008) (55)
- Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG. (1995) (55)
- Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. (2007) (53)
- Design and Expression of a Dimeric Form of Human Immunodeficiency Virus Type 1 Antibody 2G12 with Increased Neutralization Potency (2008) (52)
- A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. (2018) (52)
- HLA-A,B,C: Patterns of Polymorphism in Peptide-Binding Proteins (1989) (51)
- DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions (2018) (50)
- Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study (2021) (49)
- Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies (2017) (49)
- Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis (2000) (49)
- The molecular mechanism for receptor-stimulated iron release from the plasma iron transport protein transferrin. (2005) (49)
- The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G (2008) (48)
- Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models (2022) (48)
- Cryo-electron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L1. (2009) (48)
- Structure of a Pheromone Receptor-Associated MHC Molecule with an Open and Empty Groove (2005) (47)
- Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G* (1999) (47)
- Unusual MHC-like molecules: CD1, Fc receptor, the hemochromatosis gene product, and viral homologs. (1998) (47)
- Structures of two classes of MHC molecules elucidated: crucial differences and similarities. (1994) (47)
- Effects of peptide length and composition on binding to an empty class I MHC heterodimer. (1994) (46)
- Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue (2014) (46)
- Heterotypic interactions between transferrin receptor and transferrin receptor 2. (2003) (45)
- pH Dependence and Stoichiometry of Binding to the Fc Region of IgG by the Herpes Simplex Virus Fc Receptor gE-gI* (2004) (45)
- Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein. (2004) (45)
- Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies (2021) (45)
- Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane* (2008) (44)
- Antibody engineering for increased potency, breadth and half-life (2015) (44)
- Drift of the HIV-1 Envelope Glycoprotein gp120 toward Increased Neutralization Resistance over the Course of the Epidemic: a Comprehensive Study Using the Most Potent and Broadly Neutralizing Monoclonal Antibodies (2014) (44)
- Expression and Circular Dichroism Studies of the Extracellular Domain of the α Subunit of the Nicotinic Acetylcholine Receptor* (1997) (43)
- A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo (2015) (43)
- Dimeric 2G12 as a Potent Protection against HIV-1 (2010) (42)
- Designed oligomers of cyanovirin-N show enhanced HIV neutralization (2011) (41)
- Evaluation of CD4-CD4i Antibody Architectures Yields Potent, Broadly Cross-Reactive Anti-Human Immunodeficiency Virus Reagents (2009) (40)
- Immunization expands HIV-1 V3-glycan specific B-cells in mice and macaques (2019) (40)
- An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G. (2010) (38)
- Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies (2021) (38)
- Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies (2021) (38)
- Circular dichroism determination of class I MHC‐peptide equilibrium dissociation constants (1997) (37)
- BIAcore: a microchip-based system for analyzing the formation of macromolecular complexes. (1995) (36)
- A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity (2010) (35)
- Convergent antibody responses to SARS-CoV-2 in convalescent individuals (2020) (35)
- Expression and structural studies of fasciclin I, an insect cell adhesion molecule. (1993) (34)
- Model for the interaction of T-cell receptors with peptide/MHC complexes. (1989) (34)
- Composition of pH-sensitive triad in C-lobe of human serum transferrin. Comparison to sequences of ovotransferrin and lactoferrin provides insight into functional differences in iron release. (2005) (34)
- Structural characterization of GASDALIE Fc bound to the activating Fc receptor FcγRIIIa. (2016) (34)
- Zn-alpha2-glycoprotein, an MHC class I-related glycoprotein regulator of adipose tissues: modification or abrogation of ligand binding by site-directed mutagenesis. (2006) (34)
- Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies (2020) (34)
- Single-Chain Fv-Based Anti-HIV Proteins: Potential and Limitations (2011) (34)
- Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1. (2015) (34)
- Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies (2021) (33)
- The Herpes Virus Fc Receptor gE-gI Mediates Antibody Bipolar Bridging to Clear Viral Antigens from the Cell Surface (2014) (33)
- Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY (2011) (32)
- Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York (2021) (31)
- Peptide interaction with a class I major histocompatibility complex-encoded molecule: allosteric control of the ternary complex stability. (1996) (31)
- Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers (2020) (30)
- The crystal structure of CHIR-AB1: a primordial avian classical Fc receptor. (2008) (30)
- Comparison of FcRn- and pIgR-Mediated Transport in MDCK Cells by Fluorescence Confocal Microscopy (2010) (30)
- A model for T cell receptor and MHC/peptide interaction. (1989) (30)
- Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody (2019) (29)
- Crystal structure of human FcaRI (2003) (29)
- Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. (2013) (29)
- Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate (2020) (28)
- Crystal structure of TNFα complexed with a poxvirus MHC-related TNF binding protein (2009) (28)
- MHC homologs in the nervous system — they haven’t lost their groove (2006) (28)
- A freeze substitution fixation-based gold enlarging technique for EM studies of endocytosed Nanogold-labeled molecules. (2007) (27)
- Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine (2012) (26)
- Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography (2017) (25)
- The molecular mechanism of sulfated carbohydrate recognition by the cysteine-rich domain of mannose receptor. (2001) (24)
- Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers (2021) (24)
- Enzymatic cleavage of a CD4 immunoadhesin generates crystallizable, biologically active Fd-like fragments. (1990) (24)
- IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand‐induced redistribution (2002) (23)
- Structural insights into antibody-mediated mucosal immunity. (2006) (22)
- Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas (2015) (22)
- A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus (2019) (22)
- Generation of monoclonal antibodies against soluble human T cell receptor polypeptides (1991) (22)
- Computational determination of the structure of rat Fc bound to the neonatal Fc receptor. (1998) (21)
- Silver enhancement of Nanogold particles during freeze substitution for electron microscopy (2008) (18)
- Mechanisms of virus dissemination in bone marrow of HIV-1–infected humanized BLT mice (2019) (17)
- Tolerization of adult mice to immunodominant proteins before monoclonal antibody production. (1999) (17)
- An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein (2020) (17)
- Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env (2021) (16)
- A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques (2020) (16)
- Azethoxyl nitroxide spin labels. ESR studies involving thiourea crystals, model membrane systems and chromatophores, and chemical reduction with ascorbate and dithiothreitol. (1979) (16)
- Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells (2020) (16)
- Structural biology in the fight against COVID-19 (2021) (16)
- Extended repertoire of permissible peptide ligands for HLA‐B*2702 (1996) (15)
- Biophysical and Biochemical Characterization of Avian Secretory Component Provides Structural Insights into the Evolution of the Polymeric Ig Receptor (2016) (15)
- Structure of an HIV-2 gp120 in Complex with CD4 (2015) (15)
- Engineering and expression of a secreted murine TCR with reduced N-linked glycosylation. (1994) (13)
- Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease (2021) (12)
- X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer. (2017) (12)
- Harnessing Avidity: Quantifying the Entropic and Energetic Effects of Linker Length and Rigidity for Multivalent Binding of Antibodies to HIV-1 (2018) (11)
- Crystal structure of a hemojuvelin-binding fragment of neogenin at 1.8Å. (2011) (11)
- Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation (2021) (11)
- Characterization of Antibody Bipolar Bridging Mediated by the Human Cytomegalovirus Fc Receptor gp68 (2016) (10)
- A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch (2020) (9)
- Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice (2017) (9)
- Nanogold as a Specific Marker for Electron Cryotomography (2009) (9)
- Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype (2020) (7)
- Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1) (2020) (7)
- Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes (2022) (7)
- Phosphatidyl inositol-linked forms of a murine class I MHC molecule expressed on Chinese hamster ovary cells retain peptide binding capability and alloreactivity. (1994) (7)
- Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer (2021) (7)
- Erratum: Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis (Nature Cell Biology (2000) vol. 2 (953-957)) (2003) (7)
- Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization (2022) (7)
- Rapid Identification of Neutralizing Antibodies against SARS-CoV-2 Variants by mRNA Display (2021) (7)
- Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (7)
- Structural Basis for Enhanced Hiv-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12 (2015) (7)
- Cryoelectron tomography of homophilic adhesion mediated by the neural cell adhesion molecule L 1 (2009) (7)
- TCR recognition and selection in vivo. (1989) (6)
- Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody (2020) (6)
- How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika (2021) (6)
- The Evolution of Interdependence in a Four-Way Mealybug Symbiosis (2021) (6)
- The Hereditary Hemochromatosis Gene and Iron Homeostasis (1999) (5)
- Not Second Class: The First Class II MHC Crystal Structure (2015) (5)
- A possible basis for major histocompatibility complex-restricted T-cell recognition. (1989) (5)
- HEMOCHROMATOSIS PROTEIN HFE COMPLEXED WITH TRANSFERRIN RECEPTOR (2000) (5)
- Can we use structural knowledge to design a protective vaccine against HIV‐1? (2019) (5)
- V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1 (2016) (5)
- Not just Salk (2017) (5)
- Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody (2019) (4)
- CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals (2022) (4)
- A naturally arising broad and potent CD4-binding site antibody with low somatic mutation (2022) (4)
- In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission (2020) (4)
- Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies (2021) (4)
- Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease (2021) (3)
- CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR (2000) (3)
- Finding the groove (2006) (3)
- Bispecific antibody prevents SARS-CoV-2 escape and protects mice from disease (2021) (3)
- B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection (2022) (3)
- Expression and crystallization of a soluble form of Drosophila fasciclin III. (1994) (3)
- IgG transcytosis and recycling by FcRn expressed in MDCK cells reveals ligand‐induced redistribution (2002) (3)
- Publisher Correction: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody (2020) (3)
- Comparative analysis of anti-polyglutamine Fab crystals grown on Earth and in microgravity (2016) (3)
- Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display (2022) (3)
- LEM2 and CHMP7 function in ESCRT-dependent nuclear envelope closure in yeast and human cells (2016) (3)
- Structure/function studies of major histocompatibility antigens. (1989) (3)
- Comparison of orthorhombic and monoclinic crystal structures of HLA-A2. (1989) (3)
- Multiscale Imaging of HIV-1 Transmission in Humanized Mice. (2017) (3)
- Mosaic RBD nanoparticles protect against multiple sarbecovirus challenges in animal models (2022) (2)
- Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice (2020) (2)
- Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2 and zoonotic coronaviruses (2020) (2)
- Engineering Antibodies to Enhance Activity and Increase Half-life (2014) (2)
- Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates (2018) (2)
- Innovative vaccine approaches—a Keystone Symposia report (2022) (2)
- HIV-1 CD4-binding site germline antibody–Env structures inform vaccine design (2022) (2)
- Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2 (2023) (2)
- Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers (2022) (2)
- Structure of Classical Class I MHC Molecules (2016) (1)
- Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk with altered NTD dynamics (2023) (1)
- Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope (2021) (1)
- 3 – Structure of a Human Histocompatibility Molecule: Implications for its Interactions with Peptides and T Cell Receptors (1990) (1)
- Neutralization of SARS-CoV-2 and zoonotic coronavirus threats by mosaic nanoparticle vaccination (2020) (1)
- Author response: Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography (2017) (1)
- Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor (2003) (1)
- Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk and enhanced NTD dynamics (2022) (1)
- Crystal structure of human FcaRI bound to IgA1-Fc (2003) (1)
- Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals (2022) (1)
- NEONATAL FC RECEPTOR, PH 6.5 (1998) (1)
- D106 overcoming Hiv pathways for escape using rationally-designed anti-hiv antibodies (2013) (1)
- Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102 (2020) (1)
- Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses (2023) (1)
- Comparing methods for immobilizing HIV-1 SOSIPs in ELISAs that evaluate antibody binding (2022) (1)
- In vitro characterization of engineered red blood cells as viral traps against HIV-1 and SARS-CoV-2 (2021) (1)
- 785 SARS-COV-2 INFECTS ENTEROCYTES IN VIVO AND CAN PERSIST UP TO 7 MONTHS FOLLOWING RESOLUTION OF SYMPTOMS (2021) (1)
- Supplemental Information for Structural basis for enhanced neutralization of HIV-1 by a dimeric IgG form of the glycan-recognizing antibody 2 G 12 (2013) (1)
- Engineering HIV Immunogens to Elicit IOMA-like Antibodies Targeting the CD4 Binding Site (2018) (1)
- Cryo-EM Structures of HIV-1 trimer bound to CD4-mimetics M48U1 and BNM-III-170 adopt a CD4-bound open conformation (2020) (1)
- Erratum: The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model (2007) (1)
- N‐Terminal Modification of Gly‐His‐Tagged Proteins with Azidogluconolactone (2021) (1)
- SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies (2020) (1)
- CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2) (2001) (0)
- Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology (2023) (0)
- CRYSTAL STRUCTURE OF THE INSECT IMMUNE PROTEIN HEMOLIN: A NEW DOMAIN ARRANGEMENT WITH IMPLICATIONS FOR HOMOPHILIC ADHESION (1998) (0)
- HFE (HUMAN) HEMOCHROMATOSIS PROTEIN (1999) (0)
- Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056 (2021) (0)
- Crystal structure of the teleost fish polymeric Ig receptor (pIgR) ectodomain (2016) (0)
- Zn-alpha-2-glycoprotein; baculo-ZAG PEG 200, no glycerol (2004) (0)
- Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19 (0)
- Structure of NIH45-46 Fab in complex with gp120 of 93TH057 HIV (2011) (0)
- Distinguishing Healthy and Diseased Cells: MHC Class I Homologues and their Receptors (2003) (0)
- Crystal structure of the cysteine rich domain of mannose receptor complexed with Acetylgalactosamine-4-sulfate (2000) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C032 (2021) (0)
- Crystal structure of broadly neutralizing antibody HEPC3 (2018) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1) (2021) (0)
- Non-Canonical ESCRT Structures and Functions (2016) (0)
- Use of Click-Chemistry to Make Bivalent Antibodies for Redirection of T Cells: Proof of Concept in an In Vitro HIV Model (2020) (0)
- Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice (2021) (0)
- Crystal Structure of 10-1074 Fab (2012) (0)
- Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan (2012) (0)
- Structure of 2G12 IgG Dimer (2014) (0)
- BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195 (2017) (0)
- Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain (2006) (0)
- Designing occluded-open Env-based immunogens for HIV-1. (2023) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG7-15 (0)
- Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII (2018) (0)
- Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope (2021) (0)
- negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 (2015) (0)
- Zn-alpha-2-glycoprotein; baculo-ZAG no PEG, no glycerol (2004) (0)
- Engineering Improved Antibodies Against HIV (2014) (0)
- Crystal Structure of Germline Antibody PGT121-GL Fab (2012) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C032 (2021) (0)
- Don C. Wiley (1944–2001) (2002) (0)
- CRYSTAL STRUCTURE OF THE NEONATAL FC RECEPTOR COMPLEXED WITH A HETERODIMERIC FC (2001) (0)
- Crystal structure of the SF12 Fab (2019) (0)
- receptor 2 Heterotypic interactions between transferrin receptor and transferrin (2002) (0)
- Crystal structure of germ-line precursor of NIH45-46 Fab (2013) (0)
- Zn-alpha-2-glycoprotein; CHO-ZAG PEG 400 (2004) (0)
- Novel highly potent CD4bs bNAb with restricted pathway to HIV-1 escape (2019) (0)
- Author response: Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies (2017) (0)
- HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 (2020) (0)
- B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 (2019) (0)
- Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118 (2021) (0)
- A Model System to Investigate Antibody Bipolar Bridging Mediated by gE‐gI, a Herpes Virus Fc Receptor (2012) (0)
- HIV prevention research : The relay race continues Researchers gathered at the International AIDS Conference focused on long-term efforts to control the spread of HIV (2008) (0)
- NON-FCRN BINDING FC FRAGMENT OF RAT IGG2A (2001) (0)
- Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab (2010) (0)
- Crystal Structure of the Murine MHC Class Ib Molecule M10.5 (2005) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105 (2020) (0)
- Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Far Eastern Subtype) (2021) (0)
- Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa (2016) (0)
- Viral immunity: Basic mechanisms and therapeutic applications—a Keystone Symposia report (2023) (0)
- Crystal structure of GASDALIE IgG1 Fc (2016) (0)
- Targeting HIV using Structure-Based Rational Design of Antibodies (2014) (0)
- Evaluation of CD4-CD4i Antibody Architectures Yields Potent, Broadly Cross-Reactive Anti-Human Immunodeficiency Virus Reagents (cid:1) † (2009) (0)
- Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR (2004) (0)
- Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab (2019) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20 (0)
- Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022 (2021) (0)
- Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 (2019) (0)
- The structural basis for the anti-inflammatory activity of sialylated antibodies (THER5P.822) (2014) (0)
- Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII (2017) (0)
- Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022 (2021) (0)
- Crystal Structure of 354BG1 Fab (2017) (0)
- 3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074 (2016) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144 (2020) (0)
- Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2 (2014) (0)
- In vitro characterization of engineered red blood cells as potent viral traps against HIV-1 and SARS-CoV-2 (2020) (0)
- Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody (2011) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C098 (2021) (0)
- Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques (2019) (0)
- Crystal structure of 426c.TM4deltaV1-3 p120 (2016) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22 (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C135 (2020) (0)
- Lower Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an Inflammatory Phenotype (2020) (0)
- Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022 (2021) (0)
- CD169(+) macrophages mediate retrovirus trans-infection of permissive lymphocytes to establish infection in vivo (2016) (0)
- Structural analysis of a protein complex in the immune system (1996) (0)
- Modeling Entropic and Energetic Effects of Linker Length and Rigidity within Synthetic HIV-1 Antibodies designed to Bind Bivalently to Env Spikes (2018) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1) (2020) (0)
- Neutralizing antibodies against coronaviruses (2021) (0)
- CRYSTAL STRUCTURE OF THE ECTODOMAIN OF METHUSELAH (2001) (0)
- Crystal structure of anti-Zika antibody Z021 bound to Zika virus envelope protein DIII (2018) (0)
- Intracellular Trafficking of an Antibody Bipolar Bridged Complex of HSV‐1 gE‐gI, IgG, and a Viral Antigen (2013) (0)
- Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 (2013) (0)
- Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP (2019) (0)
- crystal structure of CHIR-AB1 (2008) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4) (2020) (0)
- Crystal structure of 354NC102 Fab (2017) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C080 (2021) (0)
- Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab (0)
- Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor (2015) (0)
- Lem2p (LEM2) and Cmp7p (CHMP7) function in ESCRT-dependent nuclear envelope remodeling in fission yeast (2016) (0)
- Structure of the methuselah ectodomain with peptide inhibitor (2007) (0)
- Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2) (2020) (0)
- Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody (2019) (0)
- University of Birmingham Crystal structure of LIR-2 (ILT4) at 1.8A: differences from LIR-1 (ILT2) in regions implicated in the binding of the human cytomegalovirus class I MHC homolog UL18 (2002) (0)
- Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L10 (2011) (0)
- Crystal structure of broadly neutralizing antibody AR3C (2018) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102 (2020) (0)
- Crystal structure of human monoclonal antibody HEPC46 (2018) (0)
- Potential and Limitations Single-Chain Fv-Based Anti-HIV Proteins : (2011) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104 (2020) (0)
- Sequential Immunization Strategies to Elicit HIV-1 bNAbs in Animal Models With a Polyclonal B Cell Repertoire (2018) (0)
- Engineering anti-HIV-1 antibodies to enhance activity and increase half-life (VAC11P.1104) (2015) (0)
- Structural characterization of HIV-1 Env heterotrimers bound to one or two CD4 receptors reveals intermediate Env conformations (2023) (0)
- Abstract B109: Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design (2019) (0)
- B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195 (2018) (0)
- Crystal structure of Hepatitis C virus envelope glycoprotein E2 ectodomain in complex with human antibodies HEPC3 and HEPC46 (2018) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002 (2020) (0)
- Crystal structure of 354BG18 Fab (2017) (0)
- Crystal structure of Hepatitis C virus envelope glycoprotein E2 core in complex with human antibodies HEPC3 and HEPC46 (2018) (0)
- BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195 (2020) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C099 (2021) (0)
- Data collection from very thin HLA crystals using synchrotron radiation. (1989) (0)
- Author response: The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins (2015) (0)
- University of Crystal structure of LIR-2 (ILT4) at 1.8A: differences from LIR-1 (ILT2) in regions implicated in the binding of the human cytomegalovirus class I MHC homolog UL18 (2002) (0)
- Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer (2022) (0)
- Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype) (0)
- Archaeological and Historical Resources Survey and Impact Assessment (1993) (0)
- Crystal structure of germ-line precursor of 3BNC60 Fab (2016) (0)
- Structure of human anti HIV 21c Fab (2010) (0)
- Chapter 13 Selection of an αβ T-Cell Antigen Receptor in Vivo and Expression in Vitro in a Soluble Form (1990) (0)
- Crystal Structure of Trichoplusia ni secreted ferritin (2005) (0)
- Crystal structure of 3BNC60 Fab with P61A mutation (2013) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135 (2020) (0)
- Chapter 4 Peptide ligands for Methuselah , a Drosophila G protein-coupled receptor associated with extended lifespan (2004) (0)
- Engineering Structurally-Novel Antibody-Like Reagents to Improve Neutralization of HIV (2012) (0)
- Zn-alpha-2-glycoprotein; refolded CHO-ZAG PEG 400 (2004) (0)
- 3.9 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074. (2016) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C110 (2020) (0)
- Crystal structure of NIH45-46 Fab (2011) (0)
- CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(A) (2001) (0)
- Structure of a Natively-glycosylated HIV-1 Env Reveals a New Mode for VH1-2 Antibody Recognition of the CD4 Binding Site Relevant to Vaccine Design (2017) (0)
- Crystal Structure of PGT121 Fab (2012) (0)
- Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab (2019) (0)
- Crystal structure of broadly neutralizing antibody HEPC74 (2018) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548 (2021) (0)
- Structure of CD4 mimetic BNM-III-170 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab (2021) (0)
- Mechanisms of virus dissemination in bone marrow of 3 HIV-1 – infected humanized BLT mice 4 5 6 (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119 (2020) (0)
- Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope (2018) (0)
- BG505 SOSIP in complex with sCD4, 17b, 8ANC195 (2018) (0)
- Crystal structure of 8ANC195 Fab (2014) (0)
- Crystal Structure of 2G12 IgG Dimer (2014) (0)
- Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120 (2016) (0)
- Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP (2019) (0)
- Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain (2016) (0)
- HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 (2020) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051 (2021) (0)
- A Co-receptor-mimicking Antibody Stabilizes the Displaced V1V2 Loops in a Partially Open sCD4-bound HIV-1 Envelope Complex (2018) (0)
- Crystal structure of broadly neutralizing antibody HEPC74 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain (2018) (0)
- Structure of the SARS-CoV-2 S1 subunit in complex with antibody N-612-004 (2021) (0)
- Crystal structure of Z032 Fab in complex with WNV EDIII (2020) (0)
- Selection of an αβ T Cell Antigen Receptor In Vivo and Engineering a Solulizable Form (1989) (0)
- Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR (2019) (0)
- Thwarting HIV evasion of antibody avidity with novel antibody architectures (P4489) (2013) (0)
- ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines (2023) (0)
- Peptides and peptide analogs derived from the protein hfe, and their use in the treatment of diseases caused by excess iron (1999) (0)
- Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII (2020) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1) (2020) (0)
- STRUCTURE, FUNCTION, AND DIVE1RSITY OF CLASS I MAJOR (1990) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110 (2020) (0)
- Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII (2017) (0)
- HUMAN ZINC-ALPHA-2-GLYCOPROTEIN (1999) (0)
- Title: A naturally arising broad and potent CD4-binding site antibody with low somatic mutation 1 Short Title: An HIV-1 bNAb with low somatic mutation (2022) (0)
- Crystal structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment C098 (2021) (0)
- Engineering immunity against HIV-1 using designed antibody constructs (2011) (0)
- HIV broadly neutralizing antibodies and immunological tolerance (VAC7P.988) (2014) (0)
- Crystal structure of broadly neutralizing antibody AR3X in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain (2020) (0)
- Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine (2007) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24 (0)
- Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab (2021) (0)
- Human immunodeficiency virus neutralizing antibodies and methods of use thereof [APPLICATION] (2014) (0)
- Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2) (2020) (0)
- Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Siberian Subtype) (0)
- Zn-alpha-2-glycoprotein; baculo-ZAG PEG 200 (2004) (0)
- Determination of the Crystal Structure of Human Zn-Alpha 2-Gylcoprotein, A Protein Implicated in Breast Cancer (2000) (0)
- The Path of Science in Future Tibetan Buddhist Education (2021) (0)
- Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120 (2016) (0)
- Harnessing Avidity: Quantifying Entropic and Energetic Effects of Linker Length and Rigidity Required for Multivalent Binding of Antibodies to HIV-1 Spikes (2019) (0)
- Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121 (2020) (0)
- Crystal Structure of a gE-gI/Fc complex (2006) (0)
- XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22 (2018) (0)
- Polymorphism in chicken MHC-Y class I molecules that bind lipid ligands (2019) (0)
- Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2) (2020) (0)
- ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses (2022) (0)
- Structural Basis for Germline Antibody Binding to Zika Virus Envelope Domain III (2021) (0)
- Preexposure passive transfer predicts plasma antibody levels prevent HIV-I aquisition (2014) (0)
- COMPUTATIONAL DETERMINATION OF THE STRUCTURE OF RAT FC (IGG1) BOUND TO NEONATAL FC RECEPTOR (FCRN), THEORETICAL MODEL (1998) (0)
- Combination therapy with anti-HIV-1 antibodies maintains viral suppression (2018) (0)
- Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex (2016) (0)
- Distinct Intracellular Trafficking Patterns of Host IgG by Herpes Virus Fc‐Receptors (2015) (0)
- Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120 (2018) (0)
- The Human Cytomegalovirus Fc Receptor gp 68 Binds the Fc C H 2-C H 3 Interface of IgG (2008) (0)
- cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 (2015) (0)
- Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer (2015) (0)
- Crystal structure of broadly neutralizing antibody HEPC3 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain (2018) (0)
- Rosu Maintain Meiotic Crossover Number Robust Crossover Assurance and Regulated Interhomolog Access (2014) (0)
- Co-administration of Rapamycin with a DNA/MVA SIV Vaccine Improves Memory CD8 T Cell Response and Enhances Control of SIV251 Infection (2013) (0)
- Crystal structure of a hemojuvelin-binding fragment of neogenin (2010) (0)
- Crystal structure of the ecto( Drosophila G protein-couplec with extended lifespan (2016) (0)
- Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc) (2014) (0)
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