Pamela L. Schwartzberg

Pamela L. Schwartzberg's AcademicInfluence.com Rankings

Biology

#13075

World Rank

#16600

Historical Rank

#2674

USA Rank

Immunology

#888

World Rank

#911

Historical Rank

#99

USA Rank

biology Degrees

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Biology

Pamela L. Schwartzberg's Degrees

PhD Immunology University of Pennsylvania
Bachelors Biology University of California, San Diego

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Pamela L. Schwartzberg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

A Critical Role for IL-21 in Regulating Immunoglobulin Production (2002) (1015)
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes (2000) (904)
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. (1999) (811)
Defining ‘T cell exhaustion’ (2019) (604)
SAP-controlled T-B cell interactions underlie germinal centre formation (2008) (594)
Follicular helper T cells are required for systemic autoimmunity (2009) (578)
T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3 (2005) (554)
Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency (2013) (534)
A mosaic activating mutation in AKT1 associated with the Proteus syndrome. (2011) (523)
Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. (2013) (522)
T-cell signaling regulated by the Tec family kinase, Itk. (2010) (494)
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. (1999) (440)
SAP is required for generating long-term humoral immunity (2003) (436)
SLAM family receptors and SAP adaptors in immunity. (2011) (435)
Regulation of NKT cell development by SAP, the protein defective in XLP (2005) (422)
Early Th1 cell differentiation is marked by a Tfh cell-like transition. (2011) (392)
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. (2000) (385)
Deficiency of PTEN in Jurkat T Cells Causes Constitutive Localization of Itk to the Plasma Membrane and Hyperresponsiveness to CD3 Stimulation (2000) (368)
Meiotic arrest and aneuploidy in MLH3-deficient mice (2002) (363)
Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. (2010) (362)
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha. (2011) (361)
Tec family kinases in T lymphocyte development and function. (2005) (349)
Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses (2014) (337)
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. (2010) (332)
Regulation of microRNA expression and abundance during lymphopoiesis. (2010) (328)
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness (2016) (325)
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation (2003) (314)
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1) (2009) (310)
Mice homozygous for the abl m1 mutation show poor viability and depletion of selected B and T cell populations (1991) (305)
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP (2001) (287)
Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. (1997) (285)
Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells. (1989) (284)
Selective regulation of integrin–cytoskeleton interactions by the tyrosine kinase Src (1999) (282)
Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection (2019) (272)
A Role for Thymic Stromal Lymphopoietin in CD4+ T Cell Development (2004) (249)
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. (2011) (246)
Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence (1989) (241)
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. (2006) (224)
SAP Regulates TH2 Differentiation and PKC-θ-Mediated Activation of NF-κB1 (2004) (223)
Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation (2010) (220)
Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. (2000) (218)
Molecular and cellular pathogenesis of X‐linked lymphoproliferative disease (2005) (217)
SLAM receptors and SAP influence lymphocyte interactions, development and function (2009) (211)
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. (2009) (209)
Mutation of Tec family kinases alters T helper cell differentiation (2001) (204)
Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection (1984) (202)
SAP regulates T cell–mediated help for humoral immunity by a mechanism distinct from cytokine regulation (2006) (158)
Tec Family Kinases Modulate Thresholds for Thymocyte Development and Selection (2000) (157)
TEC-family kinases: regulators of T-helper-cell differentiation (2005) (156)
Itk Functions to Control Actin Polymerization at the Immune Synapse through Localized Activation of Cdc42 and WASP (2003) (154)
Kinase-Independent Functions for Itk in TCR-Induced Regulation of Vav and the Actin Cytoskeleton1 (2005) (152)
The many faces of Src: multiple functions of a prototypical tyrosine kinase (1998) (151)
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. (2012) (145)
Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia (2006) (145)
Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells (2014) (144)
α-Synuclein Is Phosphorylated by Members of the Src Family of Protein-tyrosine Kinases* (2001) (139)
Improved generation of C57BL/6J mouse embryonic stem cells in a defined serum‐free media (2004) (130)
TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. (2004) (128)
TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. (2015) (128)
Tec kinases regulate T‐lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk (2009) (124)
The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction (2019) (123)
Effects of Systemically Administered Hydrocortisone on the Human Immunome (2016) (121)
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-γ-induced cell death (2008) (121)
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. (2004) (119)
Requirements for selection of conventional and innate T lymphocyte lineages. (2007) (118)
T follicular helper cell diversity and plasticity. (2013) (118)
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production. (2011) (117)
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans. (2009) (117)
SH2D1A Regulates T-dependent Humoral Autoimmunity (2004) (116)
Requirement for Tec Kinases in Chemokine-Induced Migration and Activation of Cdc42 and Rac (2004) (113)
Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis. (2012) (111)
Tec kinases: modulators of lymphocyte signaling and development. (2001) (111)
Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. (2001) (109)
Beyond calcium: new signaling pathways for Tec family kinases. (2002) (108)
Tec family kinases in lymphocyte signaling and function. (2000) (107)
Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. (2007) (96)
Type I IFN Induces Binding of STAT1 to Bcl6: Divergent Roles of STAT Family Transcription Factors in the T Follicular Helper Cell Genetic Program (2014) (96)
rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases (1999) (93)
Identification of Rlk, a Novel Protein Tyrosine Kinase with Predominant Expression in the T Cell Lineage (*) (1995) (91)
Deletion mutants of Moloney murine leukemia virus which lack glycosylated gag protein are replication competent (1983) (87)
A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice. (2002) (86)
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in lupus patients (2020) (84)
Null mutations in the SNF3 gene of Saccharomyces cerevisiae cause a different phenotype than do previously isolated missense mutations (1986) (82)
Mutations in the gag gene of Moloney murine leukemia virus: effects on production of virions and reverse transcriptase (1984) (82)
Selective targeting of ITK blocks multiple steps of HIV replication (2008) (75)
Type I interferon suppresses virus-specific B cell responses by modulating CD8+ T cell differentiation (2016) (75)
SAP Is Required for Th Cell Function and for Immunity to Influenza1 (2006) (72)
Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4 (2016) (70)
Lessons learned: new insights on the role of cytokines in COVID-19 (2021) (68)
Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes (2017) (67)
Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein. (1990) (66)
Sublethal gamma-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor beta rearrangement in recombinase activation gene 2-/- mice (1994) (66)
The Murine NK Receptor 2B4 (CD244) Exhibits Inhibitory Function Independent of Signaling Lymphocytic Activation Molecule-Associated Protein Expression1 (2004) (64)
Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity (2018) (61)
Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders (2009) (61)
Tec kinases, actin, and cell adhesion (2007) (61)
Functional Hierarchy of the N-Terminal Tyrosines of SLP-761 (2006) (60)
Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross‐regulation of cytokine production and T‐cell fates (2011) (58)
Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein. (2010) (56)
Tec Kinases Regulate TCR-Mediated Recruitment of Signaling Molecules and Integrin-Dependent Cell Adhesion1 (2005) (54)
Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting (1990) (54)
Biochemical and Genetic Evidence for a SAP-PKC-θ Interaction Contributing to IL-4 Regulation (2010) (53)
AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization (2018) (51)
Tec kinases: shaping T-cell activation through actin. (2004) (51)
Recombination between a defective retrovirus and homologous sequences in host DNA: reversion by patch repair (1985) (49)
Bone marrow B lymphocyte development in c-abl-deficient mice. (1995) (49)
X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective (2018) (48)
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk (2001) (48)
Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses1 (2008) (48)
Abnormal peripheral lymphocyte function in c-abl mutant mice. (1996) (47)
The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP). (2006) (42)
Point mutations in the P30 domain of the gag gene of Moloney murine leukemia virus. (1985) (42)
A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes (2013) (42)
Common genetic susceptibility loci link PFAPA syndrome, Behçet’s disease, and recurrent aphthous stomatitis (2020) (41)
BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8+ T cells (2021) (41)
Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases. (1997) (41)
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 (2016) (39)
Resting lymphocyte kinase (Rlk/Txk) phosphorylates the YVKM motif and regulates PI 3-kinase binding to T-cell antigen CTLA-4. (1998) (38)
A Novel ICOS-Independent, but CD28- and SAP-Dependent, Pathway of T Cell-Dependent, Polysaccharide-Specific Humoral Immunity in Response to Intact Streptococcus pneumoniae versus Pneumococcal Conjugate Vaccine1 (2008) (37)
T and B‐cell signaling in activated PI3K delta syndrome: From immunodeficiency to autoimmunity (2019) (35)
Fine-tuning lymphocyte regulation: what's new with tyrosine kinases and phosphatases? (2004) (32)
Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8+ CTLs (2017) (29)
B Cell Induction of IL-13 Expression in NK Cells: Role of CD244 and SLAM-Associated Protein (2006) (28)
Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP). (2009) (28)
CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus. (2007) (28)
Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8+ T Cell Survival, Differentiation, and Function (2018) (26)
Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells (2012) (24)
Development of Innate CD4+ and CD8+ T Cells in Itk-Deficient Mice Is Regulated by Distinct Pathways (2014) (23)
T/B‐cell interactions are more transient in response to weak stimuli in SLE‐prone mice (2014) (23)
Improved Generation of C 57 BL / 6 J Mouse Embryonic Stem Cells in a Defined Serum-Free Media (2004) (23)
Acinar Cell Apoptosis in Serpini2-Deficient Mice Models Pancreatic Insufficiency (2005) (22)
Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses (2014) (22)
Cytohesin Binder and Regulator (Cybr) Is Not Essential for T- and Dendritic-Cell Activation and Differentiation (2006) (22)
The human condition: an immunological perspective (2011) (21)
Mg2+ regulation of kinase signaling and immune function (2019) (21)
PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity (2019) (20)
CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development (2016) (20)
Cellular and Molecular Requirements for the Selection of In Vitro–Generated CD8 T Cells Reveal a Role for Notch (2013) (20)
LFA-1 signals to promote actin polymerization and upstream migration in T cells (2020) (19)
Innate PLZF+CD4+ αβ T Cells Develop and Expand in the Absence of Itk (2014) (19)
Characterization of Ly108 in the Thymus: Evidence for Distinct Properties of a Novel Form of Ly108 (2012) (19)
Amplifying Btk's signal. (2003) (19)
Biochemical and genetic analyses of the Tec kinases Itk and Rlk/Txk. (2001) (18)
Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP. (2008) (18)
Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs (2008) (16)
CD84 mediates CLL-microenvironment interactions (2017) (15)
Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus. (1993) (13)
Efficient CRISPR/Cas9‐Mediated Mutagenesis in Primary Murine T Lymphocytes (2018) (13)
Perturbation of B Cell Activation in SLAM-Associated Protein-Deficient Mice Is Associated with Changes in Gammaherpesvirus Latency Reservoirs1 (2007) (11)
Cbl Enforces an SLP76-dependent Signaling Pathway for T Cell Differentiation*S⃞ (2009) (9)
Formin the way. (2007) (9)
Lymph node choreography: B cells take the lead (2012) (9)
A mouse model of Proteus syndrome. (2019) (9)
Tampering with the Immune System (2001) (9)
Mg 2+ regulation of kinase signaling and immune function (2019) (8)
To B or not to B. (2010) (8)
Immunology. Tampering with the immune system. (2001) (7)
In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells (2022) (7)
PI3K in T Cell Adhesion and Trafficking (2021) (6)
Differential expression of IL-17A and IL-17F is coupled to TCR signaling via Itk-mediated regulation of NFATc1 (139.4) (2010) (6)
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus (2020) (6)
Cloning and characterization of an inversion breakpoint at 6q23.3 suggests a role for Map7 in sacral dysgenesis (2004) (6)
"Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes. (2022) (6)
Genetic approaches to tyrosine kinase signaling pathways in the immune system (2003) (6)
Corrigendum: Effects of Systemically Administered Hydrocortisone on the Human Immunome (2016) (5)
SAP and Lessons Learned from a Primary Immunodeficiency (2017) (5)
Ncking BCR‐mediated PI3K activation (2013) (5)
Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion (2019) (4)
Regulation of NKT Cell Development by Sap, the Adaptor Mutated in X-Linked Lymphoproliferative Disease. (2004) (4)
Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs (2007) (4)
Characterization of Ly 108 in the Thymus : Evidence for Distinct Properties of a Novel Form of Ly 108 (2012) (3)
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory (2021) (3)
Women in immunology: 2020 and beyond (2020) (3)
Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis (2022) (3)
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1–mediated adhesion in T cells (2022) (3)
16th European Colloqium on Animal Cytogenetics and Gene Mapping (2004) (3)
Src: A Model for Regulation of Intracellular Signaling Molecules (2000) (2)
The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion (2022) (2)
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation. (2023) (1)
XLP: one gene, many players. (2001) (1)
Type I interferon suppresses neutralizing antiviral B cell responses by modulating CD8+ T cell differentiation (2017) (1)
Examining multi‐level immune response to determine prevalence of COVID‐19 in pediatric tonsillectomy (2022) (1)
development, and antibody production Constitutive reductions in mTOR alter cell size, immune cell (2011) (1)
A friendly signal (1999) (1)
Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity (2018) (1)
Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children (2022) (1)
Brief Definitive Report 261 SH 2 D 1 A Regulates T-dependent Humoral Autoimmunity (2015) (1)
Transient protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion (2018) (1)
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children (2022) (1)
SLAM-associated protein (SAP)-deficiency impedes the function of T follicular helper cells in germinal center formation (99.3) (2010) (0)
Abstract 5310: mTOR knock-down mice exhibit altered T and B cell activation, differentiation and immune response (2010) (0)
PI3Kd coordinates transcriptional, epigenetic and metabolic changes to promote effector CD8 T cells at the expense of memory (2021) (0)
Molecule-Associated Protein Expression Signaling Lymphocytic Activation Exhibits Inhibitory Function Independent of The Murine NK Receptor 2B4 (CD244) (2004) (0)
Electron Solvation in Finite Systems : Femtosecond Dynamics of Iodide z ( Water ) n Anion Clusters (1999) (0)
38th Biennial American Cytogenetics Conference (2004) (0)
Tyrosines of SLP-76 Functional Hierarchy of the N-Terminal (2006) (0)
The Role of CBFβ in T Cell Development. (2004) (0)
Dichotomous regulation of progenitor-like CD8 T cells during chronic viral infection by TCF1 and type I interferon (2017) (0)
REGULATING LYMPHOCYTE INTERACTIONS: LESSONS FROM XLP (2012) (0)
Distinct Pathways Cells in Itk-Deficient Mice Is Regulated by T + and CD8 + Development of Innate CD4 (2014) (0)
effects on DNA binding and cutting. function of Moloney murine leukemia virus: Analysis of mutations in the integration (2013) (0)
Cross-talk between T cell receptor and cytokine signaling is mediated by Itk: implications for the balance between Th17 and regulatory T cells (P1141) (2013) (0)
The major Th2 polarizing component in schistosome eggs is a T2 ribonuclease (omega-1) that inhibits dendritic-T cell interaction (133.23) (2009) (0)
PROCEDURES useful for modulating angiogenesis USING TYROSINE KINASE Src. (1999) (0)
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection (2019) (0)
Cytogenetic characterization, frequency and distribution of rob t(1;29) in some Italian and Portuguese cattle breeds (2004) (0)
Dynamic intravital imaging of immune cell migration, interaction, and effector function (2009) (0)
Cellular and molecular profiling of CD8 T cell differentiation with respect to positive and negative selection in vitro reveals a role for Notch signaling (2012) (0)
The Tec kinase Itk regulates conventional versus non-conventional CD8 T cell development (87.14) (2007) (0)
Useful methods for modulating angiogenesis by the use of tyrosine kinase SRC (1999) (0)
Do Previously Isolated Missense Mutations (0)
Cellular and molecular profiling of CD8 T cell differentiation with respect to positive and negative selection in vitro reveals a role for Notch signaling (111.45) (2012) (0)
BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells (2021) (0)
Ly108 enhances PLZF expression in developing thymocytes (P4452) (2013) (0)
Construction and analysis of mutants of moloney murine leukemia virus (1985) (0)
Women in immunology: 2020 and beyond (2020) (0)
Sublethal y-Radiation Induces Differentiation of CD4- /CD8- into CD4 +/CD8 + Thymocytes without T Cell Receptor ~ Rearrangement in Recombinase (2003) (0)
Dissecting T follicular helper cell development in vivo using CRISPR (2017) (0)
Understanding signaling pathways regulating CD4 + T cell effector function (2009) (0)
Immuno imaging (SY4-3) Chairpersons: Takashi Saito, Susan Pierce (2010) (0)
Transcriptional regulation of innate αβ CD8+ T cell development in Itk deficient mice (36.35) (2010) (0)
The CD4+ T cell‐ and SAP‐dependent IgG anti‐polysaccharide response to intact Streptococcus pneumoniae, in contrast to pneumococcal conjugate vaccine, is ICOS‐independent (2008) (0)
Author response: Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion (2019) (0)
The Tec family kinase Itk is required for Th9 cell differentiation (LYM8P.642) (2015) (0)
Investigating the role of inducible T cell kinase in CD8+ T-lymphocyte cytolytic effector function (HUM8P.343) (2014) (0)
Tec family kinases in T cell receptor signaling (2001) (0)
TCF1 regulates antiviral T follicular helper (Tfh) cell responses through a negative feedback loop with IL-2 and Blimp1 (2016) (0)
Sap is necessary for mediating antigen-specific effector functions of CD4+ AND CD8+ T cells (2010) (0)
Wiskott-Aldrich症候群におけるIgA腎症の発生とそのメカニズムに関する解析~KOマウスでの検討から~ (2008) (0)
Pneumococcal Conjugate Vaccine versus Streptococcus pneumoniae Humoral Immunity in Response to Intact Cell-Dependent , Polysaccharide-Specific SAP-Dependent , Pathway of T A Novel ICOS-Independent , but CD 28-and (2008) (0)
Actin Cytoskeleton TCR-Induced Regulation of Vav and the Kinase-Independent Functions for Itk in (2005) (0)
Single-Cell Transcriptomics Identifies TOX as a Key Transcriptional Regulator of Stem- Like CD8 T Cells in Chronic Infection (2019) (0)
Faculty Opinions recommendation of Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse. (2005) (0)
Process for the modulation of angiogenesis by the tyrosine kinase src (1999) (0)
Analysis ofMutations intheIntegration Function ofMoloney MurineLeukemiaVirus: Effects on DNA Binding andCutting (1990) (0)
Helper Cell Genetic Program Transcription Factors in the T Follicular Bcl6: Divergent Roles of STAT Family Type I IFN Induces Binding of STAT1 to (2014) (0)
Dissecting the role of Phosphotidylinositol 3-Kinase (PI3K) δ in the germinal center reaction through a mouse model of hyperactivated Pik3cd (2017) (0)
Investigating signaling downstream of SLAM family members CD84 and Ly108 in thymocytes and activated T cells (99.4) (2010) (0)
Transcriptional regulation of innate {alpha}{beta} CD8+ T cell development in Itk deficient mice (2010) (0)
Reveal a Role for Notch Generated CD8 T Cells - Selection of In Vitro Cellular and Molecular Requirements for the (2013) (0)
This information is current as Expand in the Absence of Itk T Cells Develop and βα + CD 4 + Innate (2014) (0)
Humoral responses require a multi-stage T:B lymphocyte interaction process (99.5) (2010) (0)
A delicate balance of PI3K activation is required for CD8 T cell survival and generation of memory cells (2017) (0)
Unique properties of CD4 T cells selected by MHC class II expressing thymocytes (85.1) (2009) (0)
Protein Cells : Role of CD 244 and SLAM-Associated B Cell Induction of IL-13 Expression in NK Blazar and (2006) (0)
AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization (2018) (0)
CBFB Is Required for Early T Cell Development in the Thymus. (2006) (0)
TLT-1 (TREM-Like transcript-1) Protects against Hemorrhage Associated with Inflammation by Facilitating Platelet Aggregation. (2008) (0)
Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells (2021) (0)
Dynamic modulation of cortical actin at the immunological synapse controls lytic granule secretion in cytotoxic T lymphocytes (2017) (0)
Slamf6 acts as a negative regulator of NKT cell expansion in the presence of a strong agonist (2016) (0)
An essential role for Itk in Th9 differentiation via TCR-mediated induction of IL-2 and IRF4 (2016) (0)
Protein phosphatase 2A propels follicular T helper cell development in lupus. (2023) (0)
Partial rescue of Itk-/- iNKT cell development by Txk/Rlk reveals a unique role for Itk in the survival of iNKT cells. (50.40) (2010) (0)
lethality, CNS malformations, and anemia causes mitochondrial thiamine pyrophosphate depletion, embryonic Slc25a19 Knockout of (2006) (0)
Faculty Opinions recommendation of Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration. (2004) (0)
In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells (2022) (0)
Biochemical and Genetic Evidence for a Signaling Lymphocytic Activation Molecule-Associated Protein–Protein Kinase C-u Interaction Contributing to IL-4 Regulation (2010) (0)
Multiscale integration of human and single-cell variations reveals unadjuvanted vaccine high responders are naturally adjuvanted (2023) (0)
Faculty Opinions recommendation of Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. (2005) (0)

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