Paola Arlotta
#36,562
Most Influential Person Now
Italian molecular biologist and neuroscientist
Paola Arlotta's AcademicInfluence.com Rankings
Paola Arlottabiology Degrees
Biology
#3413
World Rank
#5226
Historical Rank
Molecular Biology
#1443
World Rank
#1470
Historical Rank
Neuroscience
#1918
World Rank
#1974
Historical Rank
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Biology
Paola Arlotta's Degrees
- PhD Molecular Biology University of Milan
- Bachelors Biotechnology University of Milan
Why Is Paola Arlotta Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paola Arlotta is the Golub Family Professor of Stem Cell and Regenerative Biology at Harvard University and chair of the Harvard Stem Cell and Regenerative Biology . Her research focuses on the development of neuron types in the cerebral cortex. She is best known for her work using 3D cerebral organoids derived from human induced pluripotent stem cells to study cortical development in neurodegenerative and neuropsychiatric disorders.
Paola Arlotta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neuronal subtype specification in the cerebral cortex (2007) (1461)
- Neuronal Subtype-Specific Genes that Control Corticospinal Motor Neuron Development In Vivo (2005) (1042)
- Cell diversity and network dynamics in photosensitive human brain organoids (2017) (789)
- Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. (2011) (750)
- Multiple knockout mouse models reveal lincRNAs are required for life and brain development (2013) (637)
- Individual brain organoids reproducibly form cell diversity of the human cerebral cortex (2019) (495)
- Fezl Is Required for the Birth and Specification of Corticospinal Motor Neurons (2005) (472)
- Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2 (2020) (325)
- Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex (2014) (274)
- SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes (2008) (266)
- Ctip2 Controls the Differentiation of Medium Spiny Neurons and the Establishment of the Cellular Architecture of the Striatum (2008) (261)
- Generating neuronal diversity in the mammalian cerebral cortex. (2015) (260)
- Voltage imaging and optogenetics reveal behavior dependent changes in hippocampal dynamics (2019) (220)
- Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo (2013) (211)
- DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex (2015) (209)
- Excitatory Projection Neuron Subtypes Control the Distribution of Local Inhibitory Interneurons in the Cerebral Cortex (2011) (204)
- Novel Subtype-Specific Genes Identify Distinct Subpopulations of Callosal Projection Neurons (2009) (196)
- The promises and challenges of human brain organoids as models of neuropsychiatric disease (2016) (194)
- Transgenic Mice Expressing a Truncated Form of the High Mobility Group I-C Protein Develop Adiposity and an Abnormally High Prevalence of Lipomas* (2000) (147)
- A Radial Glia-Specific Role of RhoA in Double Cortex Formation (2012) (144)
- Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain (2015) (135)
- Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission (2018) (126)
- Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons (2014) (113)
- In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes (2019) (112)
- Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo (2010) (111)
- The ethics of experimenting with human brain tissue (2018) (110)
- Molecular logic of cellular diversification in the mouse cerebral cortex (2021) (105)
- Conditional Knock-Out of β-Catenin in Postnatal-Born Dentate Gyrus Granule Neurons Results in Dendritic Malformation (2007) (101)
- Loss of COUP-TFI Alters the Balance between Caudal Ganglionic Eminence- and Medial Ganglionic Eminence-Derived Cortical Interneurons and Results in Resistance to Epilepsy (2011) (94)
- Autism genes converge on asynchronous development of shared neuron classes (2022) (86)
- Development-Inspired Reprogramming of the Mammalian Central Nervous System (2014) (83)
- Diversity Matters: A Revised Guide to Myelination. (2016) (79)
- Cerebral cortex assembly: generating and reprogramming projection neuron diversity (2015) (73)
- Present and future of modeling human brain development in 3D organoids. (2017) (67)
- SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes (2008) (64)
- Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease (2017) (62)
- Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex. (2019) (62)
- Neuron class–specific responses govern adaptive myelin remodeling in the neocortex (2020) (61)
- Programmable Sequence-Specific Transcriptional Regulation of Mammalian Genome Using Designer TAL Effectors (2011) (55)
- The Human Cell Atlas White Paper (2018) (55)
- Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons (2015) (55)
- Constitutive and Induced Neurogenesis in the Adult Mammalian Brain: Manipulation of Endogenous Precursors toward CNS Repair (2004) (54)
- Cell diversity in the human cerebral cortex: from the embryo to brain organoids (2019) (54)
- Adult axolotls can regenerate original neuronal diversity in response to brain injury (2016) (54)
- Organoids required! A new path to understanding human brain development and disease (2018) (48)
- Genetic dissection of the glutamatergic neuron system in cerebral cortex (2021) (44)
- Induction of adult neurogenesis: molecular manipulation of neural precursors in situ. (2006) (44)
- 3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo. (2020) (43)
- Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS (2004) (41)
- Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex (2012) (36)
- Homeotic Transformations of Neuronal Cell Identities (2015) (35)
- Multiscale 3D phenotyping of human cerebral organoids (2020) (34)
- Sensitive spatial genome wide expression profiling at cellular resolution (2020) (34)
- Brains in metamorphosis: reprogramming cell identity within the central nervous system (2014) (32)
- Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons (2010) (31)
- Induction of Adult Neurogenesis (2003) (30)
- Molecular development of corticospinal motor neuron circuitry. (2007) (30)
- Seven actionable strategies for advancing women in science, engineering, and medicine. (2015) (30)
- CD4+ T Cell Responses to Self- and Mutated p53 Determinants During Tumorigenesis in Mice1 (2000) (28)
- All-optical electrophysiology reveals brain-state dependent changes in hippocampal subthreshold dynamics and excitability (2018) (28)
- High Mobility Group I Proteins Interfere with the Homeodomains Binding to DNA* (1997) (28)
- Stage‐specific and opposing roles of BDNF, NT‐3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry (2004) (25)
- Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. (2018) (25)
- A nomenclature consensus for nervous system organoids and assembloids (2022) (24)
- The repair of complex neuronal circuitry by transplanted and endogenous precursors (2004) (24)
- Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. (2020) (22)
- Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis (2003) (20)
- Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex (2020) (20)
- The quest for myelin in the adult brain (2013) (20)
- Pyramidal neuron subtype diversity governs microglia states in the neocortex (2022) (18)
- CD4 T Cell Responses to Self- and Mutated p53 Determinants During Tumorigenesis in Mice (2000) (18)
- Programming and reprogramming neuronal subtypes in the central nervous system (2012) (18)
- Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex (2022) (17)
- Development and Regeneration of Projection Neuron Subtypes of the Cerebral Cortex (2010) (16)
- Molecular Logic of Cellular Diversification in the Mammalian Cerebral Cortex (2020) (15)
- A novel downstream positive regulatory element mediating transcription of the human high mobility group (HMG) I‐C gene (1999) (15)
- Cell replacement therapies for nervous system regeneration (2012) (14)
- Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice (2012) (13)
- Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics (2019) (13)
- The HMG I proteins (2001) (12)
- FIN-Seq: Transcriptional profiling of specific cell types in frozen archived tissue from the human central nervous system (2019) (11)
- Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes (2020) (10)
- The long non-coding RNAs : a new ( p ) layer in the “ dark matter ” (2014) (9)
- Long-term culture and electrophysiological characterization of human brain organoids (2017) (9)
- Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex (2022) (9)
- Highly reproducible human brain organoids recapitulate cerebral cortex cellular diversity. (2019) (8)
- Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression (2002) (8)
- Seq-ing the cortex one neuron at a time (2016) (8)
- [Solitary plasmacytoma of the mandible]. (1972) (6)
- Archeo-Cell Biology: Carbon Dating Is Not Just for Pots and Dinosaurs (2005) (6)
- Neuron-class specific responses govern adaptive remodeling of myelination in the neocortex (2020) (5)
- Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex (2022) (5)
- A Sip of GABA for the Cerebral Cortex (2013) (5)
- Building blocks of the cerebral cortex: from development to the dish (2015) (5)
- Dynamic Roles in Gene Activation, Development, and Tumorigenesis (2001) (5)
- How collaboration between bioethicists and neuroscientists can advance research (2022) (4)
- Specification of cortical projection neurons (2013) (4)
- FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system (2019) (4)
- Molecular development and repair of corticospinal motor neuron circuitry (2006) (3)
- Human-specific enrichment of schizophrenia risk-genes in callosal neurons of the developing neocortex (2021) (3)
- Stressed out? Healing Tips for Newly Reprogrammed Neurons. (2016) (3)
- Reshaping the brain: direct lineage conversion in the nervous system (2013) (3)
- [Reconstruction of severe loss of mandibular bone substance using metal prostheses]. (1980) (2)
- Brain organoids: the quest to decipher human-specific features of brain development. (2022) (2)
- DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex (2016) (1)
- Faculty Opinions recommendation of Direct conversion of fibroblasts to functional neurons by defined factors. (2013) (1)
- Stereological estimation of volume, total neuron number and neuronal nuclear area of chick brainstem auditory nuclei and hippocampus following prenatal patterned and unpatterned sound stimulation (2012) (1)
- Optogenetic axon guidance in embryonic zebrafish (2021) (1)
- Editorial overview: Developmental neuroscience 2017 (2017) (1)
- FIN-Seq (Frozen Immunolabeled Nuclei Sequencing) v1 (2019) (0)
- [Clinico-statistical study of tumors of the upper jaw]. (1954) (0)
- A Sip of GABA for the Cerebral Cortex (2013) (0)
- Loss of coup-tfi results in increased generation of PV-expressing interneurons and resistance to epileptic seizures (2010) (0)
- Engineering multicellular living systems—a Keystone Symposia report (2022) (0)
- Faculty Opinions recommendation of Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice. (2013) (0)
- profiles of myelin along single axons of pyramidal neurons in the neocortex. (0)
- [Xylocaine in use at the Milan Dental Clinic]. (1951) (0)
- Fate-switch of basal ganglia progenitors and reprogramming of young cortical neurons into corticospinal motor neurons (2010) (0)
- A case of Burkitt's tumor in Italy. (1970) (0)
- Probing the phenomics of noncoding RNA Genetic knockout experiments on mice confirm that some long noncoding RNA molecules have developmental functions. (2013) (0)
- Dissecting cellular diversity of cortical GABAergic cells across multiple modalities: A turning point in neuronal taxonomy. (2022) (0)
- Using molecular signals controlling embryonic development to direct the differentiation of corticospinal motor neurons (2012) (0)
- Author Correction: Molecular logic of cellular diversification in the mouse cerebral cortex (2021) (0)
- [Surgical therapy of submandibular sialolithiasis]. (1975) (0)
- [Transalveolar route in novocaine analgesia with gelatin sponge in periodontitis]. (1953) (0)
- Combining NGN 2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission Cell reports (2018) (0)
- Faculty Opinions recommendation of Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors. (2013) (0)
- The ethics of experimenting with human brain tissue (2018) (0)
- Faculty Opinions recommendation of Mice cloned from olfactory sensory neurons. (2013) (0)
- Faculty Opinions recommendation of MicroRNA-mediated conversion of human fibroblasts to neurons. (2013) (0)
- Modern views on traumatic injuries of the middle third of the facial skeleton. (Moderne vedute sulle lesioni traumatiche del terzo medio dello scheletro faciale) (1959) (0)
- Induction of Adult Cortical Neurogenesis From Neural Precursors In Situ (2003) (0)
- Nervous System Development-Inspired Reprogramming of the Mammalian Central (2014) (0)
- Fractures of the zygomatic complex. (1967) (0)
- Nociceptive behaviour and lumbar spinal NADPH-d/NOS, p-ERK AND c-FOS expression after formalin pain induction in weaned rats (2012) (0)
- The dopaminergic stabilizer, (−)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins (2012) (0)
- Tomassy Pyramidal Neurons in the Neocortex Distinct Profiles of Myelin Distribution Along Single Axons of (2014) (0)
- [Treatment of fracture of the zygomatic arch by means of metallic osteosynthesis]. (1972) (0)
- Faculty Opinions recommendation of In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons. (2013) (0)
- Neural Organoids and the Quest to Understand and Treat Psychiatric Disease (2023) (0)
- Molecular development of projection neuron types and building of local microcircuitry in the cerebral cortex (2012) (0)
- Temporally-Divergent Regulatory Mechanisms Govern Neuronal Development and Diversification in the Neocortex (2020) (0)
- [Gingival hyperplasia due to sodium diphenylhydantoinate]. (1951) (0)
- LETTER OF WELCOME (2018) (0)
- Molecular signals governing early development of corticospinal motor neurons by Fezf2 (2010) (0)
- [A case of mixed tumor of the palate]. (1976) (0)
- Cell-type specific developmental defects in PTEN-mutant cortical organoids converge on abnormal circuit activity (2022) (0)
- [Trichloroethylene in dentin hyperesthesia]. (1951) (0)
- Susan L. Solomon (1951-2022): Advocate, Innovator, Catalyst. (2022) (0)
- The repair of complex neuronal circuitry by transplanted and endogenous precursors (2004) (0)
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What Schools Are Affiliated With Paola Arlotta?
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