Paolo Sassone-Corsi
Italian molecular biologist
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Biology
Paolo Sassone-Corsi's Degrees
- PhD Molecular Biology University of Geneva
Why Is Paolo Sassone-Corsi Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paolo Sassone-Corsi was an Italian molecular biologist, epigeneticist, and researcher. He is known for his contributions in the areas of transcriptional regulation, epigenetics, circadian biology, and metabolic regulation. He is known for his contributions in the areas of transcriptional regulation, epigenetics, circadian biology, and metabolic regulation. His research primarily focused on the mechanisms that regulate transcription and their relation to metabolism and circadian clocks. His work focused on understanding how the circadian clock regulates metabolic cycles. Most notably, he discovered that SIRT1, a histone deacetylase with a critical role in gene expression and metabolism, is able to regulate the activity of the CLOCK protein. In 2011, Sassone-Corsi founded and directed the “Center for Epigenetics and Metabolism” at the University of California, Irvine.
Paolo Sassone-Corsi's Published Works
Published Works
- The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control (2008) (1282)
- Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1 (2009) (1068)
- Signaling to Chromatin through Histone Modifications (2000) (983)
- Circadian Regulator CLOCK Is a Histone Acetyltransferase (2006) (842)
- An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita (1994) (835)
- Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance. (1998) (829)
- Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. (2000) (820)
- ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology Implication for Coffin-Lowry Syndrome (2004) (773)
- A reliable method for the recovery of DNA fragments from agarose and acrylamide gels. (1981) (734)
- A Web of Circadian Pacemakers (2002) (708)
- Promoter sequences of eukaryotic protein-coding genes. (1980) (673)
- Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor (1993) (624)
- Mitotic Phosphorylation of Histone H3: Spatio-Temporal Regulation by Mammalian Aurora Kinases (2002) (618)
- CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription (1991) (606)
- Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice (1996) (590)
- Induction of proto-oncogene JUN/AP-1 by serum and TPA (1988) (584)
- Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock (2015) (557)
- Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity (2002) (542)
- Transcriptional autoregulation of the proto-oncogene fos (1988) (533)
- Reprogramming of the Circadian Clock by Nutritional Challenge (2013) (530)
- Computational Improvements Reveal Great Bacterial Diversity and High Metal Toxicity in Soil (510)
- Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3. (1999) (509)
- Decoding the Epigenetic Language of Neuronal Plasticity (2008) (505)
- Metabolism and cancer: the circadian clock connection (2009) (490)
- CLOCK-mediated acetylation of BMAL1 controls circadian function (2007) (483)
- Developmental switch of CREM function during spermatogenesis: from antagonist to activator (1992) (476)
- Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex (1990) (476)
- Metabolism and the circadian clock converge. (2013) (445)
- Chromatin remodelling and epigenetic features of germ cells (2005) (444)
- Unique Chromatin Remodeling and Transcriptional Regulation in Spermatogenesis (2002) (442)
- DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis (1997) (431)
- Light acts directly on organs and cells in culture to set the vertebrate circadian clock (2000) (430)
- fos-associated cellular p39 is related to nuclear transcription factor AP-1 (1988) (415)
- Adrenergic signals direct rhythmic expression of transcriptional represser CREM in the pineal gland (1993) (413)
- Transcription factors responsive to cAMP. (1995) (413)
- Circadian clock proteins and immunity. (2014) (411)
- Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome (1996) (405)
- Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain (1988) (403)
- PER2 controls lipid metabolism by direct regulation of PPARγ. (2010) (387)
- Signal transduction and gene regulation: the nuclear response to cAMP. (1994) (380)
- Coordination of the transcriptome and metabolome by the circadian clock (2012) (364)
- Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element. (1988) (359)
- Zebrafish Clock rhythmic expression reveals independent peripheral circadian oscillators (1998) (346)
- The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components. (2006) (342)
- c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. (1988) (339)
- Dimers, leucine zippers and DNA-binding domains. (1990) (332)
- Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development. (1996) (326)
- Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition (2012) (326)
- Circadian Clock Control by SUMOylation of BMAL1 (2005) (319)
- Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. (1998) (318)
- Signaling routes to CREM and CREB: plasticity in transcriptional activation. (1999) (314)
- Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock★ (2013) (310)
- RNA granules in germ cells. (2011) (305)
- The cyclic AMP pathway. (2012) (303)
- Connecting Threads: Epigenetics and Metabolism (2012) (295)
- Opinion: The chromatoid body: a germ-cell-specific RNA-processing centre (2007) (282)
- Light induces chromatin modification in cells of the mammalian circadian clock (2000) (274)
- Proto-oncogene fos: Complex but versatile regulation (1987) (266)
- The histone methyltransferase MLL1 permits the oscillation of circadian gene expression (2010) (263)
- Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene (2001) (261)
- Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation (2010) (259)
- More is better: Activators and repressors from the same gene (1992) (258)
- Coupling gene expression to cAMP signalling: role of CREB and CREM. (1998) (257)
- Pituitary hormone FSH directs the CREM functional switch during spermatogenesis (1993) (254)
- Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression (1994) (251)
- Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM (1995) (250)
- Transcriptional regulation by cyclic AMP-responsive factors. (2000) (237)
- Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism (2014) (236)
- Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons (2003) (235)
- Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging (2017) (231)
- Induction of CREM activator proteins in spermatids: down-stream targets and implications for haploid germ cell differentiation. (1993) (229)
- CBP-independent activation of CREM and CREB by the LIM-only protein ACT (1999) (224)
- Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis. (2005) (224)
- The functional versatility of CREM is determined by its modular structure. (1993) (218)
- Mammalian circadian clock and metabolism – the epigenetic link (2010) (217)
- Riding Tandem: Circadian Clocks and the Cell Cycle (2007) (214)
- Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family. (2002) (214)
- Multilevel regulation of the circadian clock (2000) (211)
- The emerging link between cancer, metabolism, and circadian rhythms (2018) (209)
- Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks (2018) (208)
- Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene. (2001) (203)
- Control of AIF-mediated Cell Death by the Functional Interplay of SIRT1 and PARP-1 in Response to DNA Damage (2006) (200)
- A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita. (1997) (198)
- Circadian clock regulates the host response to Salmonella (2013) (196)
- Transcriptional cross-talk: nuclear factors CREM and CREB bind to AP-1 sites and inhibit activation by Jun. (1992) (195)
- Multiple and cooperative phosphorylation events regulate the CREM activator function. (1993) (195)
- A multiple cytokine- and second messenger-responsive element in the enhancer of the human interleukin-6 gene: similarities with c-fos gene regulation (1989) (193)
- A Family of LIM-Only Transcriptional Coactivators: Tissue-Specific Expression and Selective Activation of CREB and CREM (2000) (193)
- Cell‐specific inhibitory and stimulatory effects of Fos and Jun on transcription activation by nuclear receptors. (1991) (190)
- Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis (2004) (189)
- Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis (2016) (185)
- Phenotypic Rescue of a Peripheral Clock Genetic Defect via SCN Hierarchical Dominance (2002) (185)
- Regulation of metabolism: the circadian clock dictates the time (2012) (182)
- IP-1: A dominant inhibitor of Fos/Jun whose activity is modulated by phosphorylation (1991) (180)
- Identification of p90RSK as the probable CREB-Ser133 kinase in human melanocytes. (1995) (179)
- Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. (2006) (175)
- A cell-based system that recapitulates the dynamic light-dependent regulation of the vertebrate clock (2001) (169)
- Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor (2005) (166)
- Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis. (2007) (165)
- Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM. (2002) (164)
- DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation. (2003) (163)
- Cross-talk in signal transduction: TPA-inducible factor jun/AP-1 activates cAMP-responsive enhancer elements. (1990) (162)
- No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse. (2003) (161)
- Defining the Independence of the Liver Circadian Clock (2019) (158)
- Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress (2017) (156)
- Testis-specific transcription mechanisms promoting male germ-cell differentiation. (2004) (155)
- Transcriptional control of circadian hormone synthesis via the CREM feedback loop. (1996) (153)
- A missense mutation in RPS6KA3 (RSK2) responsible for non-specific mental retardation (1999) (152)
- Signal transduction and gene control: the cAMP pathway. (1992) (147)
- Guidelines for Genome-Scale Analysis of Biological Rhythms (2017) (146)
- Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins. (1989) (143)
- Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function. (2000) (139)
- Metabolism control by the circadian clock and vice versa (2009) (138)
- Cyclic AMP signalling. (2001) (137)
- Mitogen-Regulated RSK2-CBP Interaction Controls Their Kinase and Acetylase Activities (2001) (137)
- Hormonal and developmental regulation of DAX-1 expression in Sertoli cells. (1996) (136)
- Circadian acetylome reveals regulation of mitochondrial metabolic pathways (2013) (135)
- Plasticity and specificity of the circadian epigenome (2010) (134)
- Genome-Wide Profiling of the Core Clock Protein BMAL1 Targets Reveals a Strict Relationship with Metabolism (2010) (133)
- Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells (2006) (132)
- Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet. (2017) (130)
- The circadian clock: a framework linking metabolism, epigenetics and neuronal function (2012) (130)
- Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy. (1993) (129)
- Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis. (2019) (127)
- Heterodimerization of c-Jun with ATF-2 and c-Fos is required for positive and negative regulation of the human urokinase enhancer. (1995) (126)
- Circadian control by the reduction/oxidation pathway: Catalase represses light-dependent clock gene expression in the zebrafish (2007) (126)
- The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1 (2003) (126)
- Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions. (1992) (125)
- Transcriptional regulation of the mouse steroidogenic acute regulatory protein gene by the cAMP response-element binding protein and steroidogenic factor 1. (2003) (125)
- Orphan Receptor DAX-1 Is a Shuttling RNA Binding Protein Associated with Polyribosomes via mRNA (2000) (123)
- Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans‐acting factor. (1984) (122)
- Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis (2006) (122)
- The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation (2003) (121)
- Light Induction of a Vertebrate Clock Gene Involves Signaling through Blue-Light Receptors and MAP Kinases (2002) (121)
- Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids. (2002) (121)
- ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun (1989) (120)
- SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression (2012) (118)
- A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro (1985) (117)
- Chromatin remodeling, metabolism and circadian clocks: the interplay of CLOCK and SIRT1. (2009) (117)
- CREM-Dependent Transcription in Male Germ Cells Controlled by a Kinesin (2002) (115)
- A direct role of SRY and SOX proteins in pre-mRNA splicing (2002) (115)
- Pituitary follicle-stimulating hormone (FSH) induces CREM gene expression in Sertoli cells: involvement in long-term desensitization of the FSH receptor. (1995) (114)
- Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene (1995) (114)
- Cyclic AMP signalling and cellular proliferation: regulation of CREB and CREM (1997) (114)
- DAX-1 blocks steroid production at multiple levels. (1998) (113)
- Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions. (2015) (112)
- AP‐1 complex and c‐fos transcription are involved in TPA provoked and trans‐synaptic inductions of the tyrosine hydroxylase gene: Insights into long‐term regulatory mechanisms (1992) (112)
- Time after time: inputs to and outputs from the mammalian circadian oscillators (2002) (109)
- Gut microbiota directs PPARγ‐driven reprogramming of the liver circadian clock by nutritional challenge (2016) (107)
- Metabolic Signaling to Chromatin. (2016) (105)
- CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics (2012) (105)
- The circadian clock and cell cycle: interconnected biological circuits. (2013) (105)
- Cycles in spatial and temporal chromosomal organization driven by the circadian clock (2013) (105)
- Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activation. (1988) (104)
- Hormonal control of gene expression: multiplicity and versatility of cyclic adenosine 3',5'-monophosphate-responsive nuclear regulators. (1993) (104)
- Transcriptional antagonist cAMP-responsive element modulator (CREM) down-regulates c-fos cAMP-induced expression. (1991) (104)
- The protooncogene c-fos is induced by corticotropin-releasing factor and stimulates proopiomelanocortin gene transcription in pituitary cells. (1991) (103)
- Common pathways in circadian and cell cycle clocks: light-dependent activation of Fos/AP-1 in zebrafish controls CRY-1a and WEE-1. (2005) (103)
- Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD. (2005) (103)
- Transcriptional regulation by trans-acting factors (1986) (102)
- Structural and functional features of transcription factors controlling the circadian clock. (2005) (102)
- Circadian Clock and Breast Cancer: A Molecular Link (2007) (102)
- CK2α phosphorylates BMAL1 to regulate the mammalian clock (2009) (101)
- Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. (2009) (99)
- Circadian clocks, epigenetics, and cancer (2015) (99)
- Transcriptional CheckpointsDetermining the Fate of Male Germ Cells (1997) (97)
- Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. (1982) (96)
- Adaptive inducibility of CREM as transcriptional memory of circadian rhythms (1996) (96)
- Molecular Cogs: Interplay between Circadian Clock and Cell Cycle. (2018) (95)
- Repression of c-fos promoter by MyoD on muscle cell differentiation (1993) (95)
- Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level. (1984) (94)
- Fasting Imparts a Switch to Alternative Daily Pathways in Liver and Muscle. (2018) (93)
- Signaling to the circadian clock: plasticity by chromatin remodeling. (2007) (93)
- Environmental stimulus perception and control of circadian clocks (2002) (92)
- Thyroid-stimulating hormone (TSH)-directed induction of the CREM gene in the thyroid gland participates in the long-term desensitization of the TSH receptor. (1995) (91)
- Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage. (2005) (90)
- Molecular clocks: mastering time by gene regulation (1998) (90)
- Modulation of c-"os gene transcription by negative and positive cellular factors (1987) (90)
- Identification of a functional cyclic adenosine 3',5'-monophosphate response element in the 5'-flanking region of the gene for transition protein 1 (TP1), a basic chromosomal protein of mammalian spermatids. (1994) (90)
- Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1 (2013) (89)
- The Circadian Clock in the Ventromedial Hypothalamus Controls Cyclic Energy Expenditure. (2016) (88)
- An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite. (1983) (87)
- The circadian epigenome: how metabolism talks to chromatin remodeling. (2013) (86)
- DAX-1 Blocks Steroid Production at Multiple Levels* * This study was supported by NIH Grant HD-17481 (to D.M.S.) and from CNRS, INSERM, Centre Hospitalier Universitaire Régional, FRM, Rhône-Poulenc Rorer (Bioavenir), Hôpital Universitaire de Strasbourg, and ARC (to P.S.-C.). (1998) (86)
- Transcriptional checkpoints determining the fate of male germ cells. (1997) (86)
- Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory (2018) (86)
- Transcriptional response to cAMP in brain: Specific distribution and induction of CREM antagonists (1993) (84)
- CREM: a master-switch governing male germ cells differentiation and apoptosis. (1998) (84)
- NAD+-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1 (2015) (84)
- cAMP-response element modulator tau is a positive regulator of testis angiotensin converting enzyme transcription. (1996) (84)
- ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals (2013) (83)
- BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis (2019) (83)
- Mutation analysis of the RSK2 gene in Coffin-Lowry patients: extensive allelic heterogeneity and a high rate of de novo mutations. (1998) (82)
- Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation. (2008) (82)
- The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling1 (2009) (82)
- The epigenetic language of circadian clocks. (2013) (80)
- Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance (2013) (80)
- Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene. (2004) (80)
- Impaired light masking in dopamine D2 receptor–null mice (2006) (80)
- Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14alpha-demethylase (CYP51) in spermatids. (1999) (79)
- Rhythmic transcription and autoregulatory loops: Winding up the biological clock (1994) (79)
- Proinflammatory Stimuli Control N-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages (2011) (78)
- A Circadian Genomic Signature Common to Ketamine and Sleep Deprivation in the Anterior Cingulate Cortex (2017) (77)
- Epigenetic control and the circadian clock: Linking metabolism to neuronal responses (2014) (77)
- Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes. (1988) (75)
- Sirtuins and the circadian clock: Bridging chromatin and metabolism (2014) (75)
- When Metabolism and Epigenetics Converge (2013) (74)
- Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation (2011) (74)
- Altered emotional and locomotor responses in mice deficient in the transcription factor CREM. (1999) (74)
- A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products (1986) (73)
- Bindarit: an anti-inflammatory small molecule that modulates the NFκB pathway. (2012) (73)
- Mammalian Bufadienolide Is Synthesized From Cholesterol in the Adrenal Cortex by a Pathway That Is Independent of Cholesterol Side-Chain Cleavage (2000) (73)
- Role of Glucocorticoids and cAMP-Mediated Repression in Limiting Corticotropin-Releasing Hormone Transcription during Stress (2005) (73)
- SirT1 is required in the male germ cell for differentiation and fecundity in mice (2014) (73)
- Chromatin landscape and circadian dynamics: Spatial and temporal organization of clock transcription (2014) (72)
- Communicating clocks shape circadian homeostasis (2021) (71)
- Unraveling the mechanisms of the vertebrate circadian clock: zebrafish may light the way (2002) (69)
- Linking Oxygen to Time: The Bidirectional Interaction Between the Hypoxic Signaling Pathway and the Circadian Clock (2013) (68)
- Coupled and uncoupled induction of fos and jun transcription by different second messengers in cells of hematopoietic origin. (1990) (68)
- Lipopolyamine‐Mediated Transfection Allows Gene Expression Studies in Primary Neuronal Cells (1990) (68)
- The time of metabolism: NAD+, SIRT1, and the circadian clock. (2011) (67)
- Differential expression of the jun family members in rat brain. (1991) (67)
- Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention. (2013) (67)
- Regulation of gene expression in post-meiotic male germ cells: CREM-signalling pathways and male fertility (2006) (67)
- Temporal Association of Protamine 1 with the Inner Nuclear Membrane Protein Lamin B Receptor during Spermiogenesis* (2004) (66)
- Regulation of spermatogenesis by small non-coding RNAs: role of the germ granule. (2014) (65)
- Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver. (1998) (64)
- Minireview: NAD+, a circadian metabolite with an epigenetic twist. (2012) (63)
- Developmental maturation of pineal gland function: synchronized CREM inducibility and adrenergic stimulation. (1995) (62)
- Gonadotropins regulate inducible cyclic adenosine 3',5'-monophosphate early repressor in the rat ovary: implications for inhibin alpha subunit gene expression. (1998) (62)
- Circadian clock: linking epigenetics to aging. (2014) (62)
- Co-induction of jun B and c-fos in a subset of neurons in the spinal cord. (1991) (61)
- Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript. (1993) (60)
- Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1* (2014) (59)
- The RelB subunit of NFκB acts as a negative regulator of circadian gene expression (2012) (59)
- Block of T lymphocyte differentiation by activation of the cAMP‐dependent signal transduction pathway. (1996) (59)
- Cyclic AMP signalling pathway and cellular proliferation: induction of CREM during liver regeneration (1997) (59)
- Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells (2010) (59)
- Common light signaling pathways controlling DNA repair and circadian clock entrainment in zebrafish (2009) (58)
- X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein (2002) (58)
- Ketamine Influences CLOCK:BMAL1 Function Leading to Altered Circadian Gene Expression (2011) (57)
- Goals for signal transduction pathways: linking up with transcriptional regulation. (1994) (57)
- Promotion of specific in vitro transcription by excised "TATA" box sequences inserted in a foreign nucleotide environment. (1981) (57)
- SIRT1 Relays Nutritional Inputs to the Circadian Clock Through the Sf1 Neurons of the Ventromedial Hypothalamus. (2015) (55)
- DAX-1 expression in human adrenocortical neoplasms: implications for steroidogenesis. (1998) (55)
- Ectopic ICER expression in pituitary corticotroph AtT20 cells: effects on morphology, cell cycle, and hormonal production. (1997) (54)
- Borna Disease Virus Persistent Infection Activates Mitogen-activated Protein Kinase and Blocks Neuronal Differentiation of PC12 Cells* (2001) (54)
- Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer. (1984) (54)
- Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes (2009) (54)
- A Clockwork Organ (2000) (54)
- Transcription factors coupled to the cAMP-signalling pathway. (1996) (53)
- Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis. (2020) (53)
- Activation of RSK by UV-light: phosphorylation dynamics and involvement of the MAPK pathway (2000) (52)
- Circadian blueprint of metabolic pathways in the brain (2018) (52)
- Joining the dots: from chromatin remodeling to neuronal plasticity (2010) (52)
- Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products. (1985) (52)
- Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice* (2016) (52)
- What time is it? Deep learning approaches for circadian rhythms (2016) (52)
- Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver* (2015) (52)
- SF-1 (steroidogenic factor-1), C/EBPbeta (CCAAT/enhancer binding protein), and ubiquitous transcription factors NF1 (nuclear factor 1) and Sp1 (selective promoter factor 1) are required for regulation of the mouse aldose reductase-like gene (AKR1B7) expression in adrenocortical cells. (2001) (52)
- Production of fertile offspring from genetically infertile male mice. (2004) (51)
- Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men (2020) (51)
- The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control (2012) (51)
- Signaling to chromatin through histone modifications: how clear is the signal? (1998) (51)
- The Nuclear Import of TAF10 Is Regulated by One of Its Three Histone Fold Domain-Containing Interaction Partners (2005) (50)
- Activation of Jun/AP-1 by protein kinase A. (1992) (50)
- Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients. (2003) (49)
- Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species (2016) (48)
- Light-Inducible and Clock-Controlled Expression of MAP Kinase Phosphatase 1 in Mouse Central Pacemaker Neurons (2007) (48)
- Immunohistochemistry of c‐fos in Mouse Brain During Postnatal Development: Basal Levels and Changing Response to Metrazol and Kainate Injection (1991) (47)
- Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression (2020) (47)
- Metabolic rivalry: circadian homeostasis and tumorigenesis (2020) (47)
- Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock (2010) (46)
- Transcriptional cascades during spermatogenesis: pivotal role of CREM and ACT (2001) (46)
- Cross-talk in signal transduction: Ras-dependent induction of cAMP-responsive transcriptional repressor ICER by nerve growth factor (1997) (46)
- CREM: a transcriptional master switch during the spermatogenesis differentiation program. (1996) (45)
- Promoter Sequences ofEukaryotic Protein-Coding Genes (1980) (45)
- Inhibition of PDGF-induced c-jun and c-fos expression by a tyrosine protein kinase inhibitor. (1991) (45)
- Signaling to the Mammalian Circadian Clocks: In Pursuit of the Primary Mammalian Circadian Photoreceptor (2001) (45)
- Novel Insights into the Downstream Pathways and Targets Controlled by Transcription Factors CREM in the Testis (2012) (45)
- CREM, a master-switch of the transcriptional cascade in male germ cells (2000) (44)
- Nutrient‐sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock (2019) (44)
- Circadian Coordination of Antimicrobial Responses. (2017) (44)
- Genetic control of spermiogenesis: insights from the CREM gene and implications for human infertility. (2005) (44)
- Microtubule-independent and Protein Kinase A-mediated Function of Kinesin KIF17b Controls the Intracellular Transport of Activator of CREM in Testis (ACT)* (2005) (44)
- Phenotyping Circadian Rhythms in Mice (2015) (43)
- Complexity and versatility of the transcriptional response to cAMP. (1994) (43)
- Regulation of proto-oncogene fos: a paradigm for early response genes. (1988) (43)
- The transcriptional repressor ICER and cAMP-induced programmed cell death (1997) (43)
- Coupling signalling pathways to transcriptional control: nuclear factors responsive to cAMP. (1997) (43)
- Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor. (1992) (42)
- Activation of transcription via AP-1 or CREB regulatory sites is blocked by protein tyrosine phosphatases. (1991) (42)
- Human metabolomics reveal daily variations under nutritional challenges specific to serum and skeletal muscle (2018) (42)
- The dynamics of the transcriptional response to cyclic adenosine 3',5'-monophosphate: recurrent inducibility and refractory phase. (1997) (42)
- A small C-terminal sequence of Aurora B is responsible for localization and function. (2004) (42)
- Negative Control of Circadian Clock Regulator E4BP4 by Casein Kinase Iϵ-Mediated Phosphorylation (2004) (41)
- CREM: A master‐switch regulating the balance between differentiation and apoptosis in male germ cells (2000) (41)
- Rhythmic transcription: The molecular basis of circadian melatonin synthesis (1997) (40)
- Positive regulation of jun/AP-1 by E1A (1991) (40)
- Mouse Period1 (mPER1) Acts as a Circadian Adaptor to Entrain the Oscillator to Environmental Light/Dark Cycles by Regulating mPER2 Protein (2005) (40)
- Impact papers on aging in 2009 (2010) (40)
- CREM: a master-switch in the transcriptional response to cAMP. (1996) (39)
- Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit. (1983) (39)
- Estrogen mediates phosphorylation of histone H3 in ovarian follicle and mammary epithelial tumor cells via the mitotic kinase, Aurora B. (2005) (39)
- Sexy splicing: regulatory interplays governing sex determination from Drosophila to mammals (2003) (38)
- Chromatin remodeling and circadian control: master regulator CLOCK is an enzyme. (2007) (38)
- Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function. (1990) (37)
- The bacterial protein YopJ abrogates multiple signal transduction pathways that converge on the transcription factor CREB (2000) (37)
- Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells (2011) (36)
- Analysis of circadian rhythms in zebrafish. (2005) (36)
- Promoter trans-activation of protooncogenes c-fos and c-myc, but not c-Ha-ras, by products of adenovirus early region 1A. (1987) (36)
- Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation (2021) (36)
- CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock (2015) (36)
- The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis. (2001) (36)
- Circadian rhythms: Metabolic clockwork (2007) (35)
- p75 Neurotrophin Receptor Is a Clock Gene That Regulates Oscillatory Components of Circadian and Metabolic Networks (2013) (35)
- The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy (2020) (35)
- Transcriptional control in male germ cells: general factor TFIIA participates in CREM-dependent gene activation. (2003) (35)
- Epigenetic regulation of the molecular clockwork. (2013) (34)
- Inhibition of Corticotrophin‐Releasing Hormone Transcription by Inducible cAMP‐Early Repressor in the Hypothalamic Cell Line, 4B (2006) (34)
- AP-1 (Fos-Jun) regulation by IP-1: effect of signal transduction pathways and cell growth. (1992) (32)
- The chromatoid body of male germ cells: Epigenetic control and miRNA pathway (2008) (32)
- Coupling circadian rhythms of metabolism and chromatin remodelling (2015) (32)
- CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver. (2008) (32)
- Regulation of niemann-pick c1 gene expression by the 3'5'-cyclic adenosine monophosphate pathway in steroidogenic cells. (2003) (31)
- The nuclear response to cAMP: role of transcription factor CREM. (1996) (30)
- The pervasiveness and plasticity of circadian oscillations: the coupled circadian-oscillators framework (2015) (30)
- Circadian rhythms and memory formation: regulation by chromatin remodeling (2012) (30)
- Specialized rules of gene transcription in male germ cells: the CREM paradigm. (2004) (29)
- Changes in intranuclear chromatin architecture induce bipolar nuclear localization of histone variant H1T2 in male haploid spermatids. (2006) (29)
- S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling (2020) (29)
- Phosphorylation and negative regulation of the transcriptional activator CREM by p34cdc2. (1993) (28)
- Regulating the balance between differentiation and apoptosis: role of CREM in the male germ cells (1998) (28)
- PASting together the mammalian clock (1998) (28)
- CircadiOmics: circadian omic web portal (2018) (28)
- Erratum to "Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock" [Mol Metab 3 (2014) 29-41]. (2014) (28)
- Stress‐induced expression of transcriptional repressor ICER in the adrenal gland (1998) (27)
- Histone phosphorylation: how to proceed. (2003) (27)
- Distinct metabolic adaptation of liver circadian pathways to acute and chronic patterns of alcohol intake (2019) (27)
- Specific in vitro initiation of transcription on the adenovirus type 2 early and late EII transcription units. (1981) (26)
- The inducible cyclic adenosine monophosphate early repressor (ICER) in the pituitary intermediate lobe: role in the stress response (1999) (26)
- A specific programme of gene transcription in male germ cells. (2004) (26)
- Fos, Jun and CREB basic-domain peptides have intrinsic DNA-binding activity enhanced by a novel stabilizing factor. (1990) (26)
- Heat shock interferes with steroidogenesis by reducing transcription of the steroidogenic acute regulatory protein gene. (2001) (25)
- Plzf pushes stem cells (2004) (25)
- Novel regulation of cardiac force‐frequency relation by CREM (cAMP response element modulator) (2003) (25)
- The rate of aneuploidy is altered in spermatids from infertile mice. (2002) (24)
- Negative control of circadian clock regulator E4BP4 by casein kinase Iepsilon-mediated phosphorylation. (2004) (24)
- The key role of CREM in the cAMP signaling pathway in the testis (1994) (24)
- DNA bending by transcription factors CREM and CREB. (1994) (23)
- Interplay between Microbes and the Circadian Clock. (2018) (23)
- Transcription Factors, cAMP-responsive Element Modulator (CREM) and Tisp40, Act in Concert in Postmeiotic Transcriptional Regulation* (2006) (23)
- Viral enhancer activity in teratocarcinoma cells. (1985) (22)
- Timing the cell cycle (2003) (22)
- fos and jun interaction: The role of the leucine zipper (1989) (22)
- DAX‐1 and SOX6 molecular interplay results in an antagonistic effect in pre‐mRNA splicing (2009) (22)
- A Time for Metabolism and Hormones (2016) (21)
- c-fos transcriptional activation by IL-2 in mouse CTL-L2 cells is mediated through two distinct signal transduction pathways converging on the same enhancer element. (1991) (21)
- Circadian Proteins CLOCK and BMAL1 in the Chromatoid Body, a RNA Processing Granule of Male Germ Cells (2012) (21)
- CREM and ICER are differentially implicated in trans‐synaptic induction of tyrosine hydroxylase gene expression in adrenal medulla and sympathetic ganglia of rat (2001) (20)
- Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress (2018) (20)
- Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility? (2005) (20)
- Nucleosome assembly on the human c-fos promoter interferes with transcription factor binding. (1996) (20)
- The Epigenetic and Metabolic Language of the Circadian Clock (2016) (19)
- Reshaping circadian metabolism in the suprachiasmatic nucleus and prefrontal cortex by nutritional challenge (2020) (19)
- Cloning and expression of activator of CREM in testis in human testicular tissue. (2001) (18)
- BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis (2019) (18)
- Proteolytic cleavage of ALF into α‐ and β‐subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells (2005) (18)
- Molecular Mechanisms of Neuronal Cell Death: Implications for Nuclear Factors Responding to cAMP and Phorbol Esters (2002) (17)
- Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms (2021) (17)
- Peripheral Noxious Stimulation Induces CREM Expression in Dorsal Horn: Involvement of Glutamate (1997) (16)
- How pervasive are circadian oscillations? (2014) (16)
- A trans-acting factor represses the activity of the polyoma virus enhancer in undifferentiated embryonal carcinoma cells. (1987) (16)
- Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells. (2005) (16)
- Mechanisms of activation by CREB and CREM: phosphorylation, CBP, and a novel coactivator, ACT. (1998) (15)
- Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation (2020) (15)
- CREM: A Transcriptional Master Switch Governing the cAMP Response in the Testis (1996) (15)
- Analysis of histone phosphorylation: coupling intracellular signaling to chromatin remodeling. (2004) (14)
- Nuclear regulator Pygo 2 controls spermiogenesis and histone H 3 acetylation (2008) (14)
- Nuclear response to cyclic AMP: central role of transcription factor CREM (cyclic-AMP-responsive-element modulator). (1993) (14)
- Circular molecules of heterogeneous size from mitochondrial fractions of the petite-negative yeast Schizosaccharomyces pombe (1978) (14)
- A minicircular component of Acetabularia acetabulum chloroplast DNA replicating by the rolling circle. (1980) (14)
- Molecular clocks: PERpetuating the PASt (1997) (14)
- Personalized medicine and circadian rhythms: Opportunities for modern society (2020) (14)
- Stimulation of in vitro transcription from heterologous promoters by (1984) (14)
- Cryptic clues to clock function (1999) (14)
- DAX-1 and the adrenal cortex (1999) (13)
- What time is it? Deep learning approaches for circadian rhythms (2016) (13)
- Rapid-acting antidepressants and the circadian clock (2021) (13)
- fos-jun conspiracy: implications for the cell. (1990) (13)
- Local receptors as novel regulators for peripheral clock expression (2014) (13)
- Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression (2009) (13)
- Clinical and molecular evidence for DAX-1 inhibition of steroidogenic factor-1-dependent ACTH receptor gene expression. (2005) (12)
- Molecular Architecture of the Circadian Clock in Mammals -- A Time for Metabolism and Hormones (2016) (12)
- Transcription factors governing male fertility (2005) (12)
- Signaling pathways and c-fos transcriptional response--links to inherited diseases. (1995) (12)
- Inducible cAMP Early Repressor Regulates the Period 1 Gene of the Hepatic and Adrenal Clocks* (2013) (12)
- Nutrition, metabolism, and epigenetics: pathways of circadian reprogramming (2022) (12)
- Photoinducible and rhythmic ICER–CREM immunoreactivity in the rat suprachiasmatic nucleus (2005) (11)
- c-fos promoter transactivation by the tax , protein of human T-cell leukemia virus type I ( transcription / regulatory elements / oncogenesis ) (11)
- Impact papers on aging in 2009 - eScholarship (2010) (11)
- Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons. (2019) (11)
- Bindarit (2012) (10)
- Tryptophan metabolism is a physiological integrator regulating circadian rhythms (2022) (10)
- 2 μm Covalently closed non-mitochondrial circular DNA in the petite-negative yeast Schizosaccharomyces pombe (1979) (10)
- Homeobox Galore: When Reproduction Goes RHOX and Roll (2005) (10)
- The Time of Your Life (2014) (10)
- Positive regulation of the nuclear activator CREM by the mitogen-induced p70 S6 kinase. (1995) (10)
- BMAL1 Associates with NOP58 in the Nucleolus and Contributes to Pre-rRNA Processing (2020) (10)
- Rhythmic transcription: the molecular basis of oscillatory melatonin synthesis. (2000) (10)
- Characterization and purification of human fos protein generated in insect cells with a baculoviral expression vector (1990) (10)
- The Genetics of Autism Spectrum Disorders -- A Time for Metabolism and Hormones (2016) (9)
- Modification of histone proteins by serotonin in the nucleus (2019) (9)
- Rhythmic transcription and autoregulatory loops: nuclear pacemaker CREM. (1996) (9)
- Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and the Circadian Clock (2020) (8)
- Regulation of human MC2-R gene expression by CREB, CREM, and ICER in the adrenocortical cell line Y1. (2007) (8)
- Discovering light effects on the brain. (2006) (8)
- Same clock, different works (1996) (8)
- Chromatin Dynamics of Circadian Transcription (2015) (8)
- Editorial: Never Enough-On the Multiplicity and Uniqueness of Transcriptional Regulators in Postmeiotic Male Germ Cells. (2002) (8)
- Molecular clocks: A vivid loop of light (2001) (7)
- Circadian and epigenetic control of depression-like behaviors (2019) (7)
- TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1 (2008) (7)
- Stem cells: The clock within (2011) (6)
- The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments (2021) (6)
- A non-pharmacological therapeutic approach in the gut triggers distal metabolic rewiring capable of ameliorating diet-induced dysfunctions encompassed by metabolic syndrome (2020) (6)
- The central clock suffices to drive the majority of circulatory metabolic rhythms (2022) (6)
- Functional analysis of transcription factors CREB and CREM. (2003) (6)
- Coupling transcription to signaling pathways: cAMP and nuclear factor cAMP-responsive element modulator. (1997) (5)
- Mouse Period 1 ( mPER 1 ) Acts as a Circadian Adaptor to Entrain the Oscillator to Environmental Light / Dark Cycles by Regulating mPER 2 Protein (2005) (5)
- Heat shock affects trafficking of DAX-1 by inducing its rapid and reversible cytoplasmic localization (2005) (5)
- Mutagenic activity of transforming genes (1986) (5)
- On the communication pathways between the central pacemaker and peripheral oscillators. (2003) (5)
- Commentary: the year in circadian rhythms. (2010) (5)
- Proto‐oncogene fos: Factors Affecting Expression and Covalent Modification of the Gene Product (1987) (5)
- Transplantation of mouse embryo fibroblasts: an approach to study the physiological pathways linking the suprachiasmatic nucleus and peripheral clocks. (2005) (5)
- 6 Coupling transcription to signaling pathways (1997) (5)
- Doxorubicin persistently rewires cardiac circadian homeostasis in mice (2019) (5)
- The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental epilepsy (2020) (5)
- ADENOVIRUS-2 MAJOR LATE PROMOTER : SEQUENCES UPSTREAM FROM THE TATA BOX ARE ESSENTIAL FOR EFFICIENT IN VIVO AND IN VITRO TRANSCRIPTION (1982) (4)
- The circadian hippocampus and its reprogramming in epilepsy: impact for chronotherapeutics (2017) (4)
- Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells (2012) (4)
- Proto-oncogene fos: an inducible gene. (1986) (4)
- The dyad symmetry element is the molecular target for c-fos induction and inhibition during K 562 differentiation along mutually exclusive lineages (1991) (4)
- Heparin inhibits transcriptional activation by Fos and Jun oncoproteins. (1990) (4)
- Combined Gene Expression and Chromatin Immunoprecipitation From a Single Mouse Hippocampus (2021) (4)
- Editorial: Never enough--on the multiplicity and uniqueness of transcriptional regulators in postmeiotic male germ cells. (2002) (4)
- SIRT1/PARP-1 functional interplay. (2009) (4)
- A Multiple Cytokine- andSecondMessenger-Responsive Element in theEnhancer oftheHumanInterleukin-6 Gene:Similarities withc-fos GeneRegulation (1989) (3)
- Promoter transactivation of protooncogenes c-fos and c-myc , but not cHaras , by products of adenovirus early region 1 A ( cellular oncogenes / transcription / adenovirus type 2 / regulated gene expression ) (3)
- Florence-Utah symposium on the genetics of male infertility. (2008) (3)
- Universality of c-fos transcriptional regulation: the Dyad Symmetry Element mediates activation by PMA in T lymphocytes. (1991) (3)
- CREM and the transcriptional response to cyclic AMP (1996) (3)
- Circadian Metabolomics: Insights for Biology and Medicine -- A Time for Metabolism and Hormones (2016) (3)
- Rev-erbs: Integrating Metabolism Around the Clock -- A Time for Metabolism and Hormones (2016) (3)
- Stem cells of the germline: The specialized facets of their differentiation program (2008) (3)
- Dopamine D2 receptor signaling in the brain modulates circadian liver metabolomic profiles (2022) (3)
- CREM, a master-switch in the nuclear response to cAMP signaling (1995) (3)
- Commentary: The Year in Circadian Rhythms (2010) (3)
- Author Correction: Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression (2020) (3)
- Pleiotropic action of the adenovirus E1A proteins (1985) (3)
- Proinflammatory stimuli control NAPE-PLD expression in macrophages (2011) (3)
- Clock-in, clock-out: circadian timekeeping between tissues. (2020) (3)
- Novel poly (ADP-ribose) polymerases: what do we know about their biological function? (2003) (2)
- Aging brains and waning clocks on the process of habituation (2010) (2)
- Common threads: epigenetics, metabolism and the clock (2012) (2)
- The Nuclear Response to cAMP During Spermatogenesis: The Key Role of Transcription Factor CREM (1994) (2)
- A Fos-Jun element in the first intron of an α2u-globulin gene (1993) (2)
- 22nd European Congress on Obesity (ECO2015), Prague, Czech Republic, May 6-9, 2015: Abstracts (2015) (2)
- Linking Depression to Epigenetics: Role of the Circadian Clock. (2021) (2)
- The decline of induced transcription: a case of enzymatic symbiosis (2003) (2)
- The Chromatoid Body: A Specialized RNA Granule of Male Germ Cells (2011) (2)
- Title Regulation of BMAL 1 Protein Stability and Circadian Function by GSK 3 ?-Mediated Phosphorylation Permalink (2009) (2)
- Transcription Control and the Circadian Clock (2009) (2)
- Control of Metabolism by Central and Peripheral Clocks in Drosophila -- A Time for Metabolism and Hormones (2016) (2)
- A Fos-Jun element in the first intron of an alpha 2u-globulin gene. (1993) (2)
- Mutations in signal transduction pathways and inherited diseases (1992) (2)
- Circadian Biology: An Unexpected Invitee to New Time Zones (2009) (2)
- Circadian clocks and their molecular organization (2009) (2)
- Molecular clocks (joint Juan March/EMBO workshop) Madrid, May 10–12, 1999 (2000) (1)
- Molecular clocks in development (1998) (1)
- Individual products of the adenovirus 12 S and 13 S EIa mRNAs stimulate viral (1)
- Interrogating Metabolic Interactions Between Skeletal Muscle and Liver Circadian Clocks In Vivo (2022) (1)
- The Chromatoid Body and microRNA Pathways in Male Germ Cells (2007) (1)
- Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression (2001) (1)
- Plasticity of the Circadian System: Linking Metabolism to Epigenetic Control (2012) (1)
- Transcriptional Response to cAMP in the Liver (2005) (1)
- Positive Regulation ofjunIAP-1 byElA (1991) (1)
- Coupling Signal Transduction to Transcription: The Nuclear Response to cAMP (1997) (1)
- Mutations in signal transduction pathways and inherited diseases. (1992) (1)
- Epigenetic control in male germ cells: a transillumination-assisted microdissection method for the analysis of developmentally regulated events. (2008) (1)
- Factors modulating AP-1 activity (1994) (1)
- Regulatory Pathways of Liver Gene Expression: The Central Role of Cyclic AMP (2009) (1)
- Circadian rhythmic kinase CK2α phosphorylates BMAL1 to regulate the mammalian clock (2008) (1)
- fos-jun Conspiracy: implications for the cell. (1989) (1)
- Sirtuins and the Circadian Clock: Epigenetic and Metabolic Crosstalk (2016) (1)
- Brain–keratinocyte communication suffices for epidermal daily homeostasis (2022) (1)
- Epigenetic regulation of the circadian gene Per1 in the hippocampus mediates age-related changes in memory and synaptic plasticity (2018) (1)
- Blood pressure AsSAuLTed by the circadian clock. (2010) (1)
- New rhythms of our lives (1999) (1)
- Studies of heterologous promoter trans-activation by the HTLV-II tax protein. (1989) (1)
- of Acetyl-coenzyme A Synthetase 1 by SIRT 1 Protein-mediated Deacetylation Circadian Control of Fatty Acid Elongation Gene Regulation : (2014) (0)
- Control of Sleep-Wake Cycles in Drosophila -- A Time for Metabolism and Hormones (2016) (0)
- , P transcription factors CREB and CREM . expression by the cyclic AMP-responsive Cell cycle regulation of cyclin A gene (1995) (0)
- Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD (2005) (0)
- Circadian Post-transcriptional Control of Metabolism -- A Time for Metabolism and Hormones (2016) (0)
- Redox and Metabolic Oscillations in the Clockwork -- A Time for Metabolism and Hormones (2016) (0)
- Doxorubicin persistently rewires cardiac circadian homeostasis in mice (2019) (0)
- Circadian Rhythmicity and Aging: the Molecular Basis of Oscillatory Gene Expression (2004) (0)
- Circadian Analysis of Rodent Locomotor Activity in Home Cages. (2022) (0)
- ICER in rat pineal gland and retina:differences in expression as a hint from phylogeny? (1994) (0)
- BAT ’ s endogenous clock d The clock in the VMH computes light and feeding inputs to modulate (2016) (0)
- Spatial Dynamics of SIRT1 Relates to Metabolic Transitions in the Cell Nucleus (2017) (0)
- Real-Time Measurement of Energy Metabolism Over Circadian Time Using Indirect Calorimetry-Enabled Metabolic Cages. (2022) (0)
- CHAPTER 284 – Multiple Signaling Routes to Histone Phosphorylation (2003) (0)
- Proto-oncogene fos expression and post-translational modification. (1988) (0)
- Faculty Opinions recommendation of Structural mechanism of demethylation and inactivation of protein phosphatase 2A. (2008) (0)
- Table of Contents (1984) (0)
- Title Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells (2010) (0)
- An interview with Dr. Paolo Sassone-Corsi on his highly cited paper published in Cell Cycle (2009) (0)
- The Body’s Clock: Timekeeping With Food (2019) (0)
- SIGNALING TO CHROMATIN: FROM CELL PROLIFERATION TO PHYSIOLOGICAL RESPONSES (2000) (0)
- Spatial Dynamics of SIRT1 Dictate Metabolic Transitions in the Cell Nucleus (2016) (0)
- Setting the clock in Madrid. (1999) (0)
- Fos/Jun in Brain Function (2017) (0)
- The dyad symmetry element is the molecular target for c-fos induction and inhibition during K 562 differentiation along mutually exclusive lineages. (1991) (0)
- Impact papers on aging in 2009 Citation (2022) (0)
- Functional aspects of mouse homeo-domains (1985) (0)
- Transcription Factor Crem: A Key Element of the Nuclear Response to cAMP (1993) (0)
- Minireview: NAD (cid:1) , a Circadian Metabolite with an Epigenetic Twist* (2011) (0)
- Bacterial Diversity and High Metal Toxicity in Soil Computational Improvements Reveal (2007) (0)
- occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells. (2012) (0)
- Routes of Transcriptional Activation in the Testis: CREM and its Co-Activator ACT (2000) (0)
- Metabolic rivalry: circadian homeostasis and tumorigenesis (2020) (0)
- RNA Granules in Germ Cells service (2011) (0)
- Light Entrains Diurnal Cha nges in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons Graphical (2019) (0)
- Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory (2018) (0)
- LE SYNDROME DE COFFIN-LOWRY : UNE ANOMALIE DE LA TRANSDUCTION DU SIGNAL (VOIE RAS/MAP KINASE) (1997) (0)
- The emerging link between cancer, metabolism, and circadian rhythms (2018) (0)
- Florence-Utah Symposium corner: from genetics to epigenetics of male infertility. (2008) (0)
- Common threads: epigenetics, metabolism and the clock (2014) (0)
- Transcriptional Pacemaker of the cAMP Response (1996) (0)
- Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress (2018) (0)
- Supplemental Data Negative Control of Circadian Clock Regulator E 4 BP 4 by Casein Kinase (2004) (0)
- Gathering by the Red Sea highlights links between environment and epigenetics (2017) (0)
- Chromatin Dynamics of Circadian Transcription (2015) (0)
- Molecular clocks (1998) (0)
- Society for Endocrinology Transatlantic Medal Lecture (2012) (0)
- Joining the dots: epigenetics, metabolism and the circadian clock (2012) (0)
- Circadian rhythms. Same clock, different works. (1996) (0)
- Multiple Routes to Histones Phosphorylation (2003) (0)
- Nuclear Oncogenes as Transcription Factors (1991) (0)
- Gene transfer and expression: A laboratory manual By Michael Kriegler. New York: Stockton Press. (1990). 255 pp. $39.95 (1991) (0)
- The Dynamics of the Transcriptional Response to Cyclic Adenosine 3 (cid:42) ,5 (cid:42) -Monophosphate: Recurrent Inducibility and Refractory Phase (1997) (0)
- Tuning up an aged clock: Circadian clock regulation in metabolism and aging (2021) (0)
- 2 micrometer covalently closed non-mitochondrial circular DNA in the petite-negative yeast Schizosaccharomyces pombe. (1979) (0)
- SIRT 1 : linking the clock with metabolism (2014) (0)
- New statistical measurements of Saturn's rings. (1981) (0)
- Modification of histone proteins by serotonin in the nucleus (2019) (0)
- Astrocytic circadian clock control of energy expenditure by transcriptional stress responses in the ventromedial hypothalamus. (2023) (0)
- CREM: A Master-Switch Governing Transcription in Male Germ Cells (1998) (0)
- Transcription Factor ICER: Regulation in the Rat Photoneuroendocrine System (1995) (0)
- Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain. (2022) (0)
- EPIGENETICS AND METABOLISM: THE CIRCADIAN CLOCK CONNECTION (2010) (0)
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