Patricia Steeg | Academic Influence

Patricia Steeg's AcademicInfluence.com Rankings

Patricia Steeg

Law

#1929

World Rank

#2403

Historical Rank

#918

USA Rank

Common Law

#58

World Rank

#65

Historical Rank

#12

USA Rank

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Law

Patricia Steeg's Degrees

Bachelors Biology University of California, Berkeley
PhD Biomedical Sciences Stanford University

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Why Is Patricia Steeg Influential?

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According to Wikipedia, Patricia Steeg is a cancer researcher working in the field of breast cancer metastasis, and was the first person to discover the NME1 gene, which spreads breast cancer to other parts of the body. Education Steeg attended the University of Maryland, which is where she got her PhD in 1982.

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Patricia Steeg's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation (1991) (2828)
Tumor metastasis: mechanistic insights and clinical challenges (2006) (1946)
Evidence for a novel gene associated with low tumor metastatic potential. (1988) (1327)
Targeting metastasis (2016) (945)
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth (2015) (898)
Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells (1991) (576)
Metastasis suppressors alter the signal transduction of cancer cells (2003) (542)
Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer (2010) (530)
Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development (1989) (504)
Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity (1982) (466)
Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential. (1989) (432)
Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. (1994) (373)
Identification of a second human nm23 gene, nm23-H2. (1991) (373)
Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions (1995) (345)
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase (1990) (343)
Breast cancer metastasis to the central nervous system. (2005) (330)
Brain metastases as preventive and therapeutic targets (2011) (320)
Metastasis: a therapeutic target for cancer (2008) (320)
Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. (2007) (316)
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. (1993) (309)
Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo (2007) (308)
In vivo MRI of cancer cell fate at the single‐cell level in a mouse model of breast cancer metastasis to the brain (2006) (296)
Proteomics of human breast ductal carcinoma in situ. (2002) (289)
Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. (1988) (284)
Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. (2008) (272)
Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines (1994) (229)
Inhibition of cell motility after nm23 transfection of human and murine tumor cells. (1993) (225)
Nm23/nucleoside diphosphate kinase: Toward a structural and biochemical understanding of its biological functions (1995) (219)
Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas. (1993) (218)
Nm23/Nucleoside Diphosphate Kinase in Human Cancers (2000) (217)
Breast cancer metastasis: challenges and opportunities. (2009) (213)
A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential. (1993) (212)
New approaches to proteomic analysis of breast cancer (2001) (203)
Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis (2009) (201)
Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer (2009) (198)
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis (2019) (197)
Cancer metastasis as a therapeutic target. (2010) (192)
Nm23-H1 Metastasis Suppressor Phosphorylation of Kinase Suppressor of Ras via a Histidine Protein Kinase Pathway* (2002) (190)
Regulation of murine macrophage Ia antigen expression by an immune interferon-like lymphokine: inhibitory effect of endotoxin. (1982) (185)
Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer (2012) (183)
Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization (2008) (183)
Brain metastases. (2019) (182)
A framework for the development of effective anti-metastatic agents (2018) (172)
Induction of nm23 gene expression in human colonic neoplasms and equal expression in colon tumors of high and low metastatic potential. (1991) (172)
A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest. (1994) (167)
CNS Metastases in Breast Cancer: Old Challenge, New Frontiers (2013) (165)
Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphokines and recombinant interferons. (1984) (164)
Angiogenesis and colonization in the tumor metastatic process: basic and applied advances (1994) (161)
Regulation of murine macrophage Ia-antigen expression by products of activated spleen cells (1980) (156)
Antibody–drug conjugates for cancer (2019) (152)
The Biology of Metastasis to a Sanctuary Site (2007) (148)
The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model (2012) (147)
Brain metastases (2019) (146)
Metastasis suppressor genes: basic biology and potential clinical use. (2003) (145)
Cancer invasion and metastasis: positive and negative regulatory elements. (1991) (145)
Molecular biology of breast cancer metastasis: Genetic regulation of human breast carcinoma metastasis (2000) (143)
Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study. (2015) (143)
Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks (2009) (141)
Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity. (1997) (139)
Notch1 Inhibition Alters the CD44hi/CD24lo Population and Reduces the Formation of Brain Metastases from Breast Cancer (2011) (138)
Site-directed Mutation of Nm23-H1 (1997) (134)
Cancer prognostics: Past, present and p27 (1997) (127)
Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma (2014) (123)
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer. (2005) (122)
Proteomic approaches to the diagnosis, treatment, and monitoring of cancer. (2003) (121)
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. (2007) (118)
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies. (2010) (118)
Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma (1991) (117)
Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22 (2011) (117)
Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer. (2012) (115)
Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer (2016) (114)
Basic and Translational Advances in Cancer Metastasis: Nm23 (2003) (113)
The small heat shock protein hsp27 increases invasiveness but decreases motility of breast cancer cells. (1997) (105)
In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide (2008) (102)
Site-directed Mutagenesis of nm23-H1 (1996) (101)
Inhibition of cyclin D expression in human breast carcinoma cells by retinoids in vitro (1997) (101)
Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer. (2003) (100)
SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases. (2013) (99)
Embryonic expression of nm23 during mouse organogenesis. (1992) (97)
Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition. (2001) (95)
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2. (2007) (93)
The potential roles of nm23 in cancer metastasis and cellular differentiation. (1995) (92)
Reaction of geldanamycin and C17-substituted analogues with glutathione: product identifications and pharmacological implications. (2006) (89)
Clues to the function of Nm23 and Awd proteins in development, signal transduction, and tumor metastasis provided by studies of Dictyostelium discoideum. (1990) (88)
Angiogenesis inhibitors: motivators of metastasis? (2003) (88)
c-Met Ectodomain Shedding Rate Correlates with Malignant Potential (2006) (87)
Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds. (2003) (84)
Nm23-H1 Metastasis Suppressor Expression Level Influences the Binding Properties, Stability, and Function of the Kinase Suppressor of Ras1 (KSR1) Erk Scaffold in Breast Carcinoma Cells (2005) (84)
Perspective: The right trials (2012) (83)
Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene (2012) (82)
Clinical-Translational Approaches to the Nm23-H1 Metastasis Suppressor (2008) (82)
Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis. (2008) (80)
LAMC2 enhances the metastatic potential of lung adenocarcinoma (2015) (79)
Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts (2009) (77)
TPI-287, a New Taxane Family Member, Reduces the Brain Metastatic Colonization of Breast Cancer Cells (2012) (77)
Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases (2018) (77)
Pazopanib Reveals a Role for Tumor Cell B-Raf in the Prevention of HER2+ Breast Cancer Brain Metastasis (2010) (77)
Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model (2013) (76)
In Vivo Characterization of Changing Blood-Tumor Barrier Permeability in a Mouse Model of Breast Cancer Metastasis: A Complementary Magnetic Resonance Imaging Approach (2011) (72)
Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition. (2011) (72)
Cyclins and breast cancer (2004) (72)
Breast cancer metastasis: issues for the personalization of its prevention and treatment. (2013) (70)
Metastasis suppressor genes. (1991) (70)
Translational research in brain metastasis is identifying molecular pathways that may lead to the development of new therapeutic strategies. (2010) (70)
Roadblocks to translational advances on metastasis research (2013) (68)
The role of metastasis suppressor genes in metastatic dormancy. (2008) (64)
The blood–tumour barrier in cancer biology and therapy (2021) (62)
DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer. (2014) (61)
Nm23 and tumour metastasis: basic and translational advances. (1998) (61)
The role of metastasis suppressor genes in metastatic dormancy (2008) (60)
The Nm23-H1 metastasis suppressor as a translational target. (2010) (60)
Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism (2015) (59)
Tumor metastasis and nm23: current concepts. (1991) (57)
Protein–protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1 (2011) (56)
Metastasis suppressors: functional pathways (2018) (55)
Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner (2014) (54)
DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer (2011) (54)
Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models (2007) (53)
Deficient DR antigen expression on human cord blood monocytes: reversal with lymphokines. (1984) (52)
The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells (2004) (52)
Rab11a Differentially Modulates Epidermal Growth Factor-induced Proliferation and Motility in Immortal Breast Cells (2006) (51)
Pazopanib inhibits the activation of PDGFRβ-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells. (2013) (51)
Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases (2019) (51)
Translational approaches using metastasis suppressor genes (2006) (50)
Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis. (2013) (49)
NME1 protein expression and loss of heterozygosity mutations in primary human breast tumors. (1994) (48)
Nm23 and breast cancer metastasis (2004) (47)
Inhibition of signal transduction by the nm23 metastasis suppressor: Possible mechanisms (2004) (47)
A high-risk lesion for invasive breast cancer, ductal carcinoma in situ, exhibits frequent overexpression of retinoid X receptor. (1998) (46)
Endocytosis: a pivotal pathway for regulating metastasis (2020) (46)
Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain (2011) (45)
Dipyridamole prevents triple-negative breast-cancer progression (2012) (45)
Brain metastases of breast cancer. (2006) (43)
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity (2014) (43)
Mechanisms of tumor invasion and metastasis (2004) (43)
Increased sensitivity to cisplatin by nm23-transfected tumor cell lines. (1996) (43)
Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23) (1997) (42)
Perspectives on classic article: metastasis suppressor genes. (2004) (42)
Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1. (2000) (41)
A critical evaluation of biochemical activities reported for the nucleoside diphosphate kinase/Nm23/Awd family proteins: opportunities and missteps in understanding their biological functions (2011) (41)
Metastasis gets site specific. (2005) (41)
Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor-kappaB activation. (2009) (40)
Nm23/PuF Does Not Directly Stimulate Transcription through the CT Element in Vivo * (1997) (40)
Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth (2007) (40)
MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines (2004) (39)
Molecular analysis of premalignant and carcinoma in situ lesions of the human breast. (1996) (37)
Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility. (2008) (35)
Heterogeneity of Drug Target Expression Among Metastatic Lesions: Lessons from a Breast Cancer Autopsy Program (2008) (35)
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines (2014) (34)
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer (2019) (34)
Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients (2015) (34)
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines (2020) (34)
Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines (1997) (34)
Production of immune interferon by an interleukin 2-independent murine T cell line. (1982) (34)
Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis (2013) (34)
Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility and Metastasis. (2019) (34)
Quantitative assessment of the p53-Mdm2 feedback loop using protein lysate microarrays. (2007) (33)
AACR Cancer Progress Report 2012 (2012) (33)
Molecular basis of tumour metastasis. (1993) (32)
Cancer biology: Emissaries set up new sites (2005) (32)
Nucleoside diphosphate kinases, nm23, and tumor metastasis: possible biochemical mechanisms. (1992) (32)
A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival (2015) (31)
Preclinical Drug Development Must Consider the Impact on Metastasis (2009) (31)
Cyclin D1 in breast premalignancy and early breast cancer: implications for prevention and treatment. (2001) (31)
Altered gene and protein expression by Nm23-H1 in metastasis suppression (2009) (30)
NM23 protein in neoplastic and nonneoplastic thyroid tissues. (1994) (29)
Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma (2013) (28)
Cancer: Micromanagement of metastasis (2007) (28)
Nm23-H1: genetic alterations and expression patterns in tumor metastasis. (1998) (27)
In vivo single scan detection of both iron‐labeled cells and breast cancer metastases in the mouse brain using balanced steady‐state free precession imaging at 1.5 T (2011) (26)
Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer (2016) (25)
RETRACTED: FMN2 Makes Perinuclear Actin to Protect Nuclei during Conﬁned Migration and Promote Metastasis (2016) (25)
Transgenic expression of human thymidylate synthase accelerates the development of hyperplasia and tumors in the endocrine pancreas (2007) (25)
FMN 2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis (2016) (24)
Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis (2015) (24)
Role of lipopolysaccharide in regulating colony-stimulating factor-dependent macrophage proliferation in vitro. (1980) (24)
Differential gene expression in tumor metastasis: Nm23. (1996) (23)
The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities (2017) (22)
Clinical evidence for drug penetration of capecitabine and lapatinib uptake in resected brain metastases from women with metastatic breast cancer. (2013) (21)
Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer (2020) (21)
New insights into the tumor metastatic process revealed by gene expression profiling. (2005) (21)
Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage-dependent growth is associated with increased cdk2 activity (2004) (21)
Invasion and metastasis (1992) (21)
Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A. (2010) (20)
Altered Gene Expression in Tumor Metastasis: The nm23 Gene (1989) (20)
The B-Raf Status of Tumor Cells May Be a Significant Determinant of Both Antitumor and Anti-Angiogenic Effects of Pazopanib in Xenograft Tumor Models (2011) (20)
Microinjection of an nm23 specific antibody inhibits cell division in rat embryo fibroblasts. (1993) (20)
Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression (2009) (19)
Definition of regions of the human genome affected by loss of heterozygosity in primary human breast tumors (1993) (18)
BglII and EcoRI polymorphism of the human nm23-H1 gene (NME1). (1991) (18)
Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs (2020) (17)
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases. (2020) (17)
Quantitative protein network monitoring in response to DNA damage. (2008) (17)
Analysis of breast cancer in young women in the Department of Defense (DOD) database (2018) (17)
Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current. (1999) (16)
A novel method for selection of invasive tumor cells: Derivation and characterization of highly metastatic K1735 melanoma cell lines based onin vitro andin vivo invasive capacity (1988) (15)
Identification and characterization of the promoter for the human metastasis suppressor gene nm23-H1. (1996) (14)
A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007 (2010) (14)
A HER2 Antibody Drug Conjugate Controls Growth of Breast Cancer Brain Metastases in Hematogenous Xenograft Models, with Heterogeneous Blood-Tumor Barrier Penetration Unlinked to a Passive Marker. (2020) (14)
Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified (2015) (14)
An added dimension: will three-dimensional cultures improve our understanding of drug resistance? (1994) (14)
Granin expectations in breast cancer? (1996) (13)
Meaningful prevention of breast cancer metastasis: candidate therapeutics, preclinical validation, and clinical trial concerns (2014) (13)
Gene expression analysis for prediction of early brain metastasis (BM) in HER2-positive (HER2+) breast cancer patients (pts) (2008) (12)
Nm 23-H 1 Suppresses Metastasis by Inhibiting Expression of the Lysophosphatidic Acid Receptor EDG 2 (2007) (12)
Suppressor genes in breast cancer: an overview. (1992) (12)
Diminished peripheral blood monocyte DR antigen expression in systemic lupus erythematosus. (1984) (12)
Search for metastasis suppressor genes. (1989) (12)
Expression of nm23 in cell lines derived from patients with metastatic renal cell carcinoma. (1995) (12)
A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice. (2013) (10)
Molecular biology of breast cancer metastasis: 'Has it spread?': disarming one of the most terrifying questions (2000) (10)
Collapsin response mediator protein-1: a lung cancer invasion suppressor gene with nerve. (2001) (10)
Nm23, Breast Differentiation, and Cancer Metastasis (1999) (9)
13-gene signature to predict rapid development of brain metastases in patients with HER2-positive advanced breast cancer. (2012) (9)
Identification and characterization of differentially expressed genes in tumor metastasis: the nm23 gene. (1991) (8)
Metastatic models and molecular genetics of prostate cancer. (1992) (8)
Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target (2018) (8)
Genetic control of the metastatic phenotype. (1991) (8)
Metastasis Suppressor Phosphorylation of Kinase Suppressor of Ras via a Histidine Protein Kinase Pathway * (2002) (8)
Possible association of nm23 gene-expression and ki-ras point mutations with metastatic potential in human pancreatic cancer-derived cell-lines. (1993) (7)
Retraction Notice to: FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis (2018) (7)
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor (2021) (7)
Deficient DR antigen expression on human neonatal monocytes: reversal with lymphokines. (1983) (6)
Advances in Brief Identification of a Second Human nm 23 Gene , nm 23-H 2 (2006) (6)
Lapatinib prevents the metastatic colonization of EGFR+ and Her-2+ breast cancer cells in the brain. (2007) (6)
Reply to “Angiogenesis inhibitors and hypoxia” (2003) (6)
Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis (2021) (5)
The Molecular Biology of Brain Metastasis (2012) (5)
Mediator interactions regulating macrophage secretion of interleukin 1 and interferon. (1983) (5)
Breast cancer cell lines resistant to either tamoxifen or Herceptin exhibit sensitivity to the anti-IGF receptor antibody A12 in vitro (2006) (5)
Interferon Regulation of DR Antigen Expression and Alloantigen‐Presenting Capabilities of the Promyelocytic Cell Line HL60 (1985) (4)
Clinical-Translational Approaches to the Nm23-H1 (2008) (3)
Radiation and the Apo 2 L / TRAIL Apoptotic Pathway Preferentially Inhibit the Colonization of Premalignant Human Breast Cells Overexpressing (2000) (3)
RAD51 and brain metastases (BM) in patients (pts) with HER2+ breast cancer. (2011) (3)
Therapeutics for Brain Metastases, v3 (2016) (3)
Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene (2012) (3)
Bi-Directional Macrophage-Lymphocyte Interactions Modulate Immune Responses (1981) (2)
The metastatic cell: Behaviour and biochemistry By C.W. Evans. New York: Chapman and Hall. (1991). 551 pp. $115.00 (1991) (2)
Correlation of hexokinase-2 expression with overall survival and potential as a therapeutic target in the treatment of breast cancer brain metastases (2008) (2)
Paclitaxel-Hyaluronic Nano-Conjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model (2013) (2)
Keeping brain metastases dormant (2022) (2)
In vitro and In vivo Radiosensitization Induced by the DNA Methylating (2008) (2)
Cancer Therapy : Preclinical Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks (2009) (1)
Abstract 5306: Overexpression of RAD51 promotes brain metastases from breast cancer (2012) (1)
Characterization of in vivo Mammary and Prostate Tumor Xenograft Models for Growth and Response to Clinical Anticancer Agents (1999) (1)
Breast cancer advocacy and basic research: a scientist's perspective. (1998) (1)
Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis (2015) (1)
Abstract 5767: LPA1 antagonist, Debio 0719, acts as a metastasis suppressor in breast cancer (2010) (1)
Nuclear Pore Complex (2011) (1)
Abstract 4589: Overexpression of RAD51 promotes brain metastases from breast cancer. (2013) (1)
Cancer Therapy : Preclinical Pazopanib Reveals a Role for Tumor Cell B-Raf in the Prevention of HER 2 þ Breast Cancer Brain Metastasis (2010) (1)
Nm23 Metastasis Suppressor Gene (2002) (1)
Abstract PD6-01: Analysis of breast cancer in young women in the department of defense (DOD) database (2017) (1)
Abstract 1395: Docetaxel pretreatment is associated with increased incidence of CNS-metastases in a murine model of HER2-positive breast cancer (2012) (1)
A BRCA1deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity (2014) (1)
Abstract 4859: The role of LPAR1 and fibrosis in breast cancer metastasis (2017) (1)
Molecular characteristics of matched brain metastasis (BM) versus the primary breast cancer (PBC). (2009) (1)
The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model (2012) (1)
Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer (2011) (0)
Abstract POSTER-TECH-1102: Caspase 8 cooperates with IKKβ to protect ovarian cancer cells from necroptosis (2015) (0)
Abstract 1047: Role of endocytosis in NM23 mediated motility suppression (2017) (0)
CLIN-MEDICAL + RADIATION THERAPIES (2012) (0)
In vitro and In vivo Radiosensitization Induced by the DNA Methylating AgentTemozolomide (2008) (0)
A molecular portrait of breast cancer metastasis to the brain (2005) (0)
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines (2014) (0)
Cancer Metastasis: The Role of Metastasis Suppressor Genes in Metastasis (2011) (0)
29. ROLE OF AGE AND CNS MYELOID CELLS ON BREAST CANCER BRAIN METASTASIS (2020) (0)
Abstract 1478: The DNA double-strand break repair genes BARD1 and RAD51 as molecular targets for brain metastases from breast cancer (2011) (0)
Blood-Tumor Barrier’s Role in Brain Mets (2018) (0)
Abstract 3427: Interaction of two metastasis suppressors, Nm23-H1 and Gelsolin, in the proliferation and motility of MDA-MB-231 breast carcinoma cells (2012) (0)
Non-invasive visualization of differential BBB permeability and in vivo quantification of tumor volume in an experimental model of breast cancer metastasis to the brain , using Gadolinium-enhanced MRI and 3 D bSSFP (2010) (0)
Abstract 262: Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through NF-κB activation (2010) (0)
Dipyridamole prevents triple-negative breast-cancer progression (2012) (0)
A phase II study of medroxyprogesterone acetate (MPA) in patients (pts) with hormone receptor-negative (HR-) metastatic breast cancer (MBC): Translational Breast Cancer Research Consortium trial 007. (2010) (0)
In vivo Tracking of Growth and Dormancy of Solitary Cells in a Mouse Model of Breast Cancer Metastasis to Brain using MRI (2005) (0)
Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems (2022) (0)
TMIC-18. ROLE OF MICROGLIA IN THE EARLY STEPS OF THE BRAIN METASTATIC CASCADE (2016) (0)
Abstract P1-01-01: The blood-Tumor barrier as a therapeutic target to improve therapy of brain metastases of breast cancer (2018) (0)
Nelfinavir , ALeadHIVProtease Inhibitor , Is aBroad-Spectrum , AnticancerAgent that InducesEndoplasmicReticulum Stress , Autophagy , andApoptosis Invitro and Invivo (2007) (0)
Abstract A49: S6K1 promotes invasiveness of breast cancer cells in a novel model of triple-negative breast cancer metastasis (2014) (0)
Metastasizing breast carcinoma to the brain: a clinicopathologic and immunohistochemical study of 14 matched pairs. (2008) (0)
15th Annual San Antonio Breast Cancer Symposium presents Fifth Annual Antonio Flow Cytometry Forum December 7–8, 1992 (2005) (0)
Targeted Disruption of Stat 3 Signaling Inhibits Tumor Growth and Brain Metastases by Caveolin-1 Upregulation (2011) (0)
Abstract 1454: LPA1 regulated pathways that mediate breast cancer dormancy in the liver and lung (2011) (0)
52. BrMPANEL: A PUBLIC RESOURCE OF ORGANOTROPIC CELL LINES (2020) (0)
Abstract 3561: Pazopanib inhibits a subpopulation of PDGFR+ astrocytes in the neuro-inflammatory microenvironment of breast cancer brain metastases (2011) (0)
Abstract 4753: The interaction of two metastasis suppressor genes, Nm23-H1 and Gelsolin, results in synergistic phenotypes (2011) (0)
Mechanisms of breast cancer brain metastasis (2008) (0)
A Multiple Coil Array Approach for Mouse Brain Tumor Imaging (2009) (0)
Abstract 3871: Analysis of gene expression patterns downstream of multiple metastatic suppressor genes. (2013) (0)
TMIC-37. THE MICROENVIRONMENT OF A YOUNGER BRAIN IS MORE PERMISSIVE FOR BREAST CANCER BRAIN METASTASIS (2017) (0)
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer (2019) (0)
Abstract 1442: PDGFRβ activation defines a subset of astrocytes in the neuroinflammatory microenvironment of breast cancer brain metastasis, inhibitable by pazopanib. (2013) (0)
Breast Cancer Clinical Trials Should Aim to Prevent Metastases (2012) (0)
Albumin as a probe for clathrin-independent endocytosis and transcytosis into experimental brain metastases of breast cancer. (2022) (0)
The production and use of human nm23-H2 protein and on the other hand directed antibodies (1990) (0)
Abstract 2619: Whole genome and transcriptome sequencing identifies an activating mutation ofLPAR1in a patient with metastatic neuroblastoma. (2013) (0)
1 Identification and Characterization of Differentially Expressed Genes in Tumor Metastasis: Nm23 (1996) (0)
Abstract P6-11-04: Profound prevention of experimental brain metastases of breast cancer by temozolomide in a MGMT-dependent manner (2013) (0)
Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified (2015) (0)
Abstract 403: The role of HER2 in the brain metastatic cascade in breast cancer. (2013) (0)
Preclinical leads for brain metastases of breast cancer (2008) (0)
Abstract B43: Characterization of ovarian cancer cells as in vivo models for preclinical studies. (2016) (0)
Abstract 907: Brain microenvironment induced PTEN loss by microRNAs promotes brain metastasis (2016) (0)
Identification and validation of aberrantly expressed proteins in breast ductal carcinoma in situ (DCIS) and esophageal squamous cell carcinoma (ESCC) (2002) (0)
Abstract 1447: An unbiased screen for Nm23-H1 interacting proteins identifies the cytoskeletal crosslinking protein Ezrin (2011) (0)
TMIC-19. ASTROCYTIC S1P3 SIGNALING MODULATES BLOOD-TUMOR BARRIER PERMEABILITY IN BRAIN METASTASES (2017) (0)
970 Understanding the Heterogeneity of Brain Metastases from Breast Cancer : Lessons from New Models and Experimental Magnetic Resonance Imaging (2013) (0)
Abstract 2373: Heterogeneity of permeability in a preclinical model of brain metastases of breast cancer does not correlate with vascular density, HIF-1α expression, or tumor survival (2010) (0)
Abstract 1565: Pazopanib reveals B-Raf regulation of anti-angiogenesis pathways and prevents brain metastatic colonization of HER2+ breast cancer cells (2010) (0)
Abstract 3290: A novel model of breast cancer metastasis: Killing two birds with one stone (2012) (0)
The gift of absorption. (2004) (0)
The neuronal cell adhesion molecule L1CAM as a therapeutic targe in breast cancer. (2011) (0)
Capacity to Promote Tumor Cell Motility and Metastasis Nm 23-H 1 Binds to Gelsolin and Inactivates Its Actin-Severing (2013) (0)
The Gift of Absorption Patricia S. Steeg (2004) (0)
HeterogeneityofDrugTarget ExpressionAmongMetastatic Lesions : Lessons fromaBreast CancerAutopsy Program (2008) (0)
SCDT-12. IN VITRO STUDY OF ROLE OF ASTROCYTIC S1P3 IN REGULATING BLOOD-BRAIN/TUMOR BARRIER PERMEABILITY (2017) (0)
Abstract 4976: Characterization of the neuroinflammatory response in a mouse model of brain metastatic inflammatory breast cancer. (2013) (0)
Tumor Suppressors in Metastasis (2001) (0)
Nm23-H1 metastasis suppressor phosphorylates the kinase suppressor of ras protein from breast carcinoma cells (2003) (0)
468 Brain metastases: molecular analysis and therapeutic options (2004) (0)
Abstract ES3-1: Brain metastases of breast cancer (2019) (0)
Abstract 3421: Nm23, a metastasis suppressor gene, binds the cytoskeletal linker Ezrin to regulate motility (2012) (0)
Abstract OT2-06-01: Phase I/II study of T-DM1 alone versus T-DM1 and metronomic temozolomide in secondary prevention of HER2-Positive breast cancer brain metastases following stereotactic radiosurgery (2018) (0)
Factors Important to Personalizing Therapy for Preventing and Treating Metastatic Disease Semipersonalized Medicine (2013) (0)
BSCI-17. YOUNG AGE PROMOTES BREAST CANCER METASTASIS TO THE BRAIN (2019) (0)
Prediction of brain relapse by gene expression analysis in HER2-positive metastatic breast cancer patients (2008) (0)
The first mitochondrial metastasis suppressor: NME4 loss-of-function impairs organelle structure and function (2022) (0)
OS7.1 Identification and characterization of brain metastasis initiating cells (2016) (0)
NM23-H1 acts as a potent survival factor against primary AML cells and normal blast cells [Abstract] (2005) (0)
The enzymatic activity of Drosophila AWD/NDP kinase is necessary but not sufficient for its biological function. (1996) (0)
Cilengitide Inhibits Proliferation and Shows Combined Effects With Radiation in Breast Cancer Cell Lines (2013) (0)
Production ofimmuneinterferon byaninterleukin 2-independent murine Tcell line (1982) (0)
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor (2021) (0)
Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer (2016) (0)
Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer (2022) (0)
Induction of apoptosis in MMTV/PyMT mammary gland tumors with oral zebularine (2008) (0)
8 th International Congress of the NDP Kinase/Nm23/awd Family -From Basic Science to Clinical Application- (2010) (0)
Abstract P1-21-06: Phase I study of T-DM1 and metronomic temozolomide in secondary prevention of HER2+ breast cancer brain metastases following local radiation therapy (2022) (0)
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis (2019) (0)
Expedition Inspiration Fund for Breast Cancer Research Meeting 2003 (2003) (0)
LPAR1 (R163W) mutation promotes cell mobility through activation of Rho pathway. (2013) (0)
Vorinostat Enhances the Radiosensitivity of a Breast Cancer Brain Metastatic Cell Line Grown In Vitro and as Intracerebral Xenografts (2008) (0)
Abstract 2846: Pigment epithelium-derived factor (PEDF) functions as a brain metastasis suppressor of breast cancer (2011) (0)
Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases (2018) (0)
Preclinical Development TPI-287 , a New Taxane Family Member , Reduces the Brain Metastatic Colonization of Breast Cancer Cells (2012) (0)
Abstract 4330: Astrocytic S1P3 regulates blood-brain/tumor barrier permeability (2017) (0)
Production of murine immune interferon by an IL-2-independent T-cell line☆☆☆ (1982) (0)
Phase I/II study of T-DM1 alone versus T-DM1 and metronomic temozolomide in secondary prevention of HER2-positive breast cancer brain metastases following stereotactic radiosurgery. (2020) (0)
Murine Tumor Cells Transfection of Human and nm 23 Inhibition of Cell Motility after Updated (2006) (0)
Abstract 2667: L1CAM neural adhesion molecule is overexpressed in human brain metastases of breast cancer and contributes to colony formation efficiency (2011) (0)
Endocytosis: a pivotal pathway for regulating metastasis (2020) (0)
Meaningful prevention of breast cancer metastasis: candidate therapeutics, preclinical validation, and clinical trial concerns (2014) (0)
Reply to “Cyclin E — a better prognostic marker for breast cancer than cyclin D?” (1996) (0)
Abstract 2974: Combating breast cancer brain metastasis by targeting Src family kinases (2012) (0)
Cancer Therapy: Preclinical Pazopanib Reveals a Role for Tumor Cell B-Raf in the Prevention of HER2þ Breast Cancer Brain Metastasis (2010) (0)
Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases. (2023) (0)
Abstract P6-08-24: Age independently predicts worse disease-specific survival in patients diagnosed with invasive breast cancers at 50 years of age or older but not younger (2015) (0)
BrainMetsBC.org: Evaluation of a new resource for breast cancer patients with brain metastases (2008) (0)
Abstract 5125: The identification of Gelsolin as a potential binding partner of Nm23 (2010) (0)
Abstract 4933: Desmin+pericyte subpopulations correlated with blood-tumor barrier permeability in brain metastases of breast cancer (2017) (0)
Small Molecule Therapeutics Paclitaxel – Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model (2013) (0)
Preclinical testing using tumors from genetically engineered mouse mammary models. (2006) (0)

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