Patrick M. Kochanek
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Engineering Computer Science
Patrick M. Kochanek's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Patrick M. Kochanek's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest (2002) (4010)
- Treatment of traumatic brain injury with moderate hypothermia. (1997) (1048)
- Polymorphonuclear Leukocytes and Monocytes/Macrophages in the Pathogenesis of Cerebral Ischemia and Stroke (1992) (641)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. (2012) (609)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. (2003) (541)
- The far-reaching scope of neuroinflammation after traumatic brain injury (2017) (528)
- Polymorphonuclear leukocyte accumulation in brain regions with low blood flow during the early postischemic period. (1986) (498)
- Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. (2009) (386)
- Caspase‐3 Mediated Neuronal Death After Traumatic Brain Injury in Rats (2000) (386)
- Traumatic brain injuries (2016) (373)
- Inflicted Childhood Neurotrauma: New Insight into The Detection, Pathobiology, Prevention, and Treatment of Our Youngest Patients with Traumatic Brain Injury (2007) (361)
- Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system (2007) (354)
- Therapeutic hypothermia after cardiac arrest. (2002) (336)
- Innate Gender-based Proclivity in Response to Cytotoxicity and Programmed Cell Death Pathway* (2004) (326)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 1: Introduction. (2003) (302)
- Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress* (2003) (300)
- One-year study of spatial memory performance, brain morphology, and cholinergic markers after moderate controlled cortical impact in rats. (1999) (284)
- Increases in Bcl‐2 and cleavage of caspase‐1 and caspase‐3 in human brain after head injury (1999) (276)
- Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models. (1994) (270)
- Intranuclear localization of apoptosis‐inducing factor (AIF) and large scale dna fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite (2002) (255)
- Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children. (2005) (250)
- Apoptosis-Suppressor Gene bcl-2 Expression after Traumatic Brain Injury in Rats (1997) (244)
- Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making (2008) (238)
- Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats (1997) (235)
- Oxidative Stress Following Traumatic Brain Injury in Rats (2000) (233)
- Assessment of Antioxidant Reserves and Oxidative Stress in Cerebrospinal Fluid after Severe Traumatic Brain Injury in Infants and Children (2002) (232)
- Biochemical, cellular, and molecular mechanisms in the evolution of secondary damage after severe traumatic brain injury in infants and children: Lessons learned from the bedside (2000) (226)
- Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. (2011) (225)
- Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children. (1997) (213)
- Cerebrovascular response in infants and young children following severe traumatic brain injury: a preliminary report. (1997) (211)
- Clinical trials in head injury. (1999) (211)
- Critical Time Window for Intra-Arrest Cooling With Cold Saline Flush in a Dog Model of Cardiopulmonary Resuscitation (2006) (206)
- Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury (2004) (206)
- Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats. (1990) (204)
- Pathophysiology and treatment of cerebral edema in traumatic brain injury (2019) (200)
- Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children. (2002) (195)
- Pediatric critical care medicine: Planning for our research future (2003) (193)
- Severe controlled cortical impact in rats: assessment of cerebral edema, blood flow, and contusion volume. (1995) (192)
- Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients. (2004) (183)
- Starving Neurons Show Sex Difference in Autophagy* (2009) (180)
- Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis (2007) (178)
- Early neuropathologic effects of mild or moderate hypoxemia after controlled cortical impact injury in rats. (1997) (177)
- Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines. (2019) (175)
- Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. (2006) (174)
- Global lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of acute brain injury (2012) (174)
- Hypothermia attenuates the normal increase in interleukin 1 beta RNA and nerve growth factor following traumatic brain injury in the rat. (1995) (171)
- Adenosine A1 Receptor Knockout Mice Develop Lethal Status Epilepticus after Experimental Traumatic Brain Injury (2006) (165)
- Interleukin‐8 is increased in cerebrospinal fluid of children with severe head injury (2000) (161)
- Autophagy is Increased after Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant γ-glutamylcysteinyl Ethyl Ester (2008) (156)
- Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury* (2002) (155)
- Influence of granulocytopenia on canine cerebral ischemia induced by air embolism. (1989) (154)
- Reduction of Cognitive and Motor Deficits after Traumatic Brain Injury in Mice Deficient in Poly(ADP-Ribose) Polymerase (1999) (153)
- Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin‐labeled MRI (2001) (152)
- Mild Posttraumatic Hypothermia Reduces Mortality after Severe Controlled Cortical Impact in Rats (1996) (152)
- Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats. (2006) (150)
- Astrocytes Are the Major Source of Nerve Growth Factor Upregulation Following Traumatic Brain Injury in the Rat (1998) (150)
- Topical Review: Head Injury in Children (1998) (144)
- Oxidative Stress in Immature Brain after Traumatic Brain Injury (2006) (143)
- Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals (2020) (139)
- Neuronal NOS‐mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury (2006) (137)
- Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness (2008) (136)
- Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia. (2004) (136)
- Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury* (2019) (135)
- Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia. (2007) (131)
- mitochondrial pathway for biosynthesis of lipid mediators (2014) (129)
- Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice (1999) (128)
- Upregulation of Nerve Growth Factor Following Cortical Trauma (1994) (128)
- Enhanced Oxidative Stress in iNOS-Deficient Mice after Traumatic Brain Injury: Support for a Neuroprotective Role of iNOS (2005) (127)
- Delayed, spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats (2000) (127)
- Identification of Inflicted Traumatic Brain Injury in Well-Appearing Infants Using Serum and Cerebrospinal Markers: A Possible Screening Tool (2006) (125)
- Hypothermia and Hyperthermia in Children After Resuscitation From Cardiac Arrest (2000) (123)
- Effect of Soluble Complement Receptor-1 on Neutrophil Accumulation after Traumatic Brain Injury in Rats (1995) (123)
- A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest* (2010) (122)
- IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study (2014) (122)
- Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury (2006) (121)
- Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats* (2003) (121)
- Motor and cognitive functional deficits following diffuse traumatic brain injury in the immature rat. (1997) (118)
- Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury. (2000) (117)
- Inducible Nitric Oxide Synthase Expression in Cerebrovascular Smooth Muscle and Neutrophils after Traumatic Brain Injury in Immature Rats1 (1996) (115)
- Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse. (2001) (114)
- Serum Biomarkers after Traumatic and Hypoxemic Brain Injuries: Insight into the Biochemical Response of the Pediatric Brain to Inflicted Brain Injury (2006) (113)
- Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury (2002) (113)
- Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans. (1996) (113)
- Survival without brain damage after clinical death of 60–120 mins in dogs using suspended animation by profound hypothermia* (2003) (110)
- Interleukm‐1 receptor antagonist suppresses neurotrophin response in injured rat brain (1996) (109)
- Interstitial adenosine, inosine, and hypoxanthine are increased after experimental traumatic brain injury in the rat. (1998) (109)
- The simple model versus the super model: translating experimental traumatic brain injury research to the bedside. (2001) (109)
- Acute CSF interleukin-6 trajectories after TBI: Associations with neuroinflammation, polytrauma, and outcome (2015) (109)
- Identification of poly‐ADP‐ribosylated mitochondrial proteins after traumatic brain injury (2008) (107)
- Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses (2003) (107)
- Mass‐spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury (2010) (107)
- A model of diffuse traumatic brain injury in the immature rat. (1996) (105)
- Neurological sequelae of 2009 influenza A (H1N1) in children: A case series observed during a pandemic* (2010) (105)
- Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children* (2009) (105)
- Blood brain barrier permeability and acute inflammation in two models of traumatic brain injury in the immature rat: a preliminary report. (1998) (104)
- Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies (2019) (102)
- Promising strategies to minimize secondary brain injury after head trauma (2003) (102)
- Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats. (2013) (101)
- Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats. (2002) (99)
- Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice. (1999) (99)
- Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. (2019) (98)
- Autophagy in acute brain injury: Feast, famine, or folly? (2011) (97)
- Intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 are increased in the plasma of children with sepsis-induced multiple organ failure (2000) (96)
- Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. (2012) (96)
- Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats. (2000) (96)
- A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ (2003) (95)
- Pediatric Traumatic Brain Injury: Quo Vadis? (2006) (95)
- Translational Stroke Research: Vision and Opportunities (2017) (93)
- Early cerebrovascular response to head injury in immature and mature rats. (1994) (93)
- Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans. (1997) (92)
- Serum S100B concentrations are increased after closed head injury in children: a preliminary study. (2002) (92)
- Cytochrome c, a Biomarker of Apoptosis, is Increased in Cerebrospinal Fluid from Infants with Inflicted Brain Injury from Child Abuse (2005) (92)
- Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs* (2004) (92)
- Assessment of Cerebral Blood Flow and CO2 Reactivity after Controlled Cortical Impact by Perfusion Magnetic Resonance Imaging using Arterial Spin-Labeling in Rats (1997) (91)
- Emerging Therapies in Traumatic Brain Injury (2015) (88)
- Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI (2010) (87)
- The effect of brain temperature on acute inflammation after traumatic brain injury in rats. (1997) (86)
- Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup. (2014) (86)
- Effects of neutropenia on edema, histology, and cerebral blood flow after traumatic brain injury in rats. (1994) (86)
- Histopathologic response of the immature rat to diffuse traumatic brain injury. (2001) (85)
- Traumatic brain injury in infants and children: mechanisms of secondary damage and treatment in the intensive care unit. (2003) (85)
- Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction. (1988) (85)
- The Antioxidant Enzymes Glutathione Peroxidase and Catalase Increase Following Traumatic Brain Injury in the Rat (1997) (84)
- Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers. (2004) (84)
- Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: assessment of histopathologic and functional outcome. (1999) (82)
- Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury. (2012) (81)
- Mass‐spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine‐induced apoptosis (2008) (80)
- Assessment of posttraumatic polymorphonuclear leukocyte accumulation in rat brain using tissue myeloperoxidase assay and vinblastine treatment. (1992) (80)
- F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children. (2003) (80)
- Cerebral blood flow at one year after controlled cortical impact in rats: assessment by magnetic resonance imaging. (2002) (80)
- Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. (2010) (80)
- Brain Resuscitation in the Drowning Victim (2012) (77)
- The far-reaching scope of neuroinflammation after traumatic brain injury (2017) (77)
- Neutrophils do not mediate blood-brain barrier permeability early after controlled cortical impact in rats. (1999) (77)
- Experimental model of pediatric asphyxial cardiopulmonary arrest in rats (2004) (76)
- Intravenous Hydrogen Sulfide Does Not Induce Hypothermia or Improve Survival from Hemorrhagic Shock in Pigs (2011) (76)
- Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein after Pediatric Traumatic Brain Injury (2016) (75)
- Soluble adhesion molecules in CSF are increased in children with severe head injury. (1998) (75)
- Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments for a Multicenter Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (75)
- Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats. (2002) (75)
- Multiplex Assessment of Serum Biomarker Concentrations in Well-Appearing Children With Inflicted Traumatic Brain Injury (2009) (75)
- Serum Biomarkers of Brain Injury to Classify Outcome After Pediatric Cardiac Arrest* (2014) (74)
- Trajectory Analysis of Serum Biomarker Concentrations Facilitates Outcome Prediction after Pediatric Traumatic and Hypoxemic Brain Injury (2010) (74)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 5. Indications for intracranial pressure monitoring in pediatric patients with severe traumatic brain injury. (2003) (74)
- Immunohistochemical analysis of histone H3 acetylation and methylation—Evidence for altered epigenetic signaling following traumatic brain injury in immature rats (2006) (74)
- Cerebrospinal Fluid Mitochondrial DNA: A Novel DAMP in Pediatric Traumatic Brain Injury (2014) (74)
- Relationship between hyperglycemia and outcome in children with severe traumatic brain injury (2012) (73)
- Mild Hypothermia Alters Midazolam Pharmacokinetics in Normal Healthy Volunteers (2010) (73)
- Effects of Hypothermia on Traumatic Brain Injury in Immature Rats (1996) (73)
- Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children (2017) (73)
- Cerebrovascular response in children following severe traumatic brain injury (2011) (71)
- Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats (2002) (71)
- Early perfusion after controlled cortical impact in rats: Quantification by arterial spin‐labeled MRI and the influence of spin‐lattice relaxation time heterogeneity (1999) (70)
- Quinolinic Acid is Increased in CSF and Associated with Mortality after Traumatic Brain Injury in Humans (1998) (70)
- Protective Effect of the 20-HETE Inhibitor HET0016 on Brain Damage after Temporary Focal Ischemia (2006) (70)
- Magnetic Resonance Imaging Assessment of Regional Cerebral Blood Flow after Asphyxial Cardiac Arrest in Immature Rats (2009) (69)
- Antioxidant Tempol Enhances Hypothermic Cerebral Preservation during Prolonged Cardiac Arrest in Dogs (2002) (69)
- Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: Association with severity of injury and excitotoxicity (2001) (69)
- Long-term dysfunction following diffuse traumatic brain injury in the immature rat. (2000) (69)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 19. The role of anti-seizure prophylaxis following severe pediatric traumatic brain injury. (2003) (68)
- Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death. (2009) (68)
- Resuscitative hypothermia. (1996) (67)
- Caspase‐8 expression and proteolysis in human brain after severe head injury (2003) (67)
- Posttraumatic hyperemia in immature, mature, and aged rats: autoradiographic determination of cerebral blood flow. (1996) (66)
- Risk factors for mortality in children with abusive head trauma. (2012) (66)
- Detection of single- and double-strand DNA breaks after traumatic brain injury in rats: comparison of in situ labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase. (2001) (66)
- Induction of Profound Hypothermia for Emergency Preservation and Resuscitation Allows Intact Survival After Cardiac Arrest Resulting From Prolonged Lethal Hemorrhage and Trauma in Dogs (2006) (65)
- Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs. (2004) (65)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 11. Use of hyperosmolar therapy in the management of severe pediatric traumatic brain injury. (2003) (64)
- Differences in Medical Therapy Goals for Children With Severe Traumatic Brain Injury—An International Study (2013) (64)
- Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. (2009) (63)
- Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury (2001) (63)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury. (2003) (63)
- Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI. (2014) (63)
- Antibodies against Mac-1 attenuate neutrophil accumulation after traumatic brain injury in rats. (1996) (62)
- Oxidative lipidomics of programmed cell death. (2008) (62)
- Cerebrovascular and Cerebrometabolic Effects of Intracarotid Infused Platelet-Activating Factor in Rats (1988) (62)
- Minocycline Reduces Neuronal Death and Attenuates Microglial Response after Pediatric Asphyxial Cardiac Arrest (2010) (61)
- Insight into Pre-Clinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. (2016) (61)
- Platelet activating factor receptor blockade enhances recovery after multifocal brain ischemia. (1987) (61)
- Validation of the Pittsburgh Infant Brain Injury Score for Abusive Head Trauma (2016) (60)
- Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury. (2008) (58)
- International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children A Global Epidemiological Assessment Study* (2017) (57)
- Emergency Preservation and Resuscitation with Profound Hypothermia, Oxygen, and Glucose Allows Reliable Neurological Recovery after 3 h of Cardiac Arrest from Rapid Exsanguination in Dogs (2008) (57)
- Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. (2007) (57)
- Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury. (1999) (57)
- Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury. (2010) (57)
- Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. (2016) (56)
- Increased CSF Concentrations of Myelin Basic Protein After TBI in Infants and Children: Absence of Significant Effect of Therapeutic Hypothermia (2012) (56)
- Effects of prostacyclin, indomethacin, and heparin on cerebral blood flow and platelet adhesion after multifocal ischemia of canine brain. (1988) (55)
- A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy. (2011) (55)
- Pre-Clinical Testing of Therapies for Traumatic Brain Injury. (2018) (55)
- Vascular Endothelial Growth Factor Is Increased in Cerebrospinal Fluid after Traumatic Brain Injury in Infants and Children (2004) (54)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 8. Cerebral perfusion pressure. (2003) (53)
- Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury—Results From an Automated Data Collection System Time-Synched to Drug Administration (2016) (53)
- Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest (2012) (53)
- Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (52)
- α-Synuclein Levels Are Elevated in Cerebrospinal Fluid following Traumatic Brain Injury in Infants and Children: The Effect of Therapeutic Hypothermia (2010) (52)
- The utility of near infrared spectroscopy in detecting intracranial hemorrhage in children. (2012) (52)
- Severe brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in mice. (2012) (52)
- Polynitroxylated pegylated hemoglobin: A novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice* (2011) (52)
- The brain in vivo expresses the 2′,3′‐cAMP‐adenosine pathway (2012) (51)
- Anthraquinone-2-sulfonic acid (AQ2S) is A Novel Neurotherapeutic Agent (2013) (51)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 6. Threshold for treatment of intracranial hypertension. (2003) (51)
- Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale (2020) (51)
- Increases in Cerebrospinal Fluid Caffeine Concentration are Associated with Favorable Outcome after Severe Traumatic Brain injury in Humans (2008) (50)
- Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development (2015) (50)
- Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology. (2016) (50)
- Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats (2000) (50)
- Resuscitation from severe brain trauma. (1996) (50)
- Indomethacin, prostacyclin, and heparin improve postischemic cerebral blood flow without affecting early postischemic granulocyte accumulation. (1987) (49)
- Comments about the revised guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents (2012) (49)
- Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients (2020) (49)
- Urinary S100B concentrations are increased after brain injury in children: A preliminary study* (2006) (49)
- Relationship of Intracranial Pressure and Cerebral Perfusion Pressure with Outcome in Young Children after Severe Traumatic Brain Injury (2010) (49)
- Variable neuroendocrine–immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury (2015) (48)
- Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury (2019) (48)
- A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury. (2007) (48)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 4. Resuscitation of blood pressure and oxygenation and prehospital brain-specific therapies for the severe pediatric traumatic brain injury patient. (2003) (48)
- Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice. (2009) (47)
- Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: Effects on oxidative stress (2011) (47)
- Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (46)
- Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. (2009) (46)
- The relationship between brain temperature and neutrophil accumulation after traumatic brain injury in rats. (1997) (46)
- Cold stress protein RBM3 responds to temperature change in an ultra-sensitive manner in young neurons (2015) (46)
- Cardiac arrest in children (2010) (46)
- Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion (2015) (45)
- Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary (2019) (45)
- IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study (2015) (45)
- CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI (2011) (45)
- Therapeutic Hypothermia Decreases Phenytoin Elimination in Children with Traumatic Brain Injury* (2013) (45)
- Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (44)
- Intracranial pressure-monitoring systems in children with traumatic brain injury: Combining therapeutic and diagnostic tools* (2011) (43)
- Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs. (2004) (43)
- Minocycline attenuates brain tissue levels of TNF-α produced by neurons after prolonged hypothermic cardiac arrest in rats. (2014) (43)
- The Potential for Bio-Mediators and Biomarkers in Pediatric Traumatic Brain Injury and Neurocritical Care (2013) (43)
- ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI (2017) (43)
- Increased Phosphorylation of Protein Kinase B and Related Substrates after Traumatic Brain Injury in Humans and Rats (2006) (42)
- Reduced brain edema after traumatic brain injury in mice deficient in P‐selectin and intercellular adhesion molecule‐1 (2000) (42)
- Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice. (2014) (42)
- Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury (2016) (42)
- Brain tissue oxygen monitoring after severe traumatic brain injury in children: relationship to outcome and association with other clinical parameters. (2012) (41)
- Influence of PARP-1 polymorphisms in patients after traumatic brain injury. (2010) (41)
- Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements. (2013) (41)
- Polymorphonuclear leukocytes and microcirculatory perfusion in acute stroke in the SHR. (1996) (40)
- Therapeutic hypothermia for severe traumatic brain injury. (2003) (40)
- Resuscitative hypothermia: Crit Care Med 1996; 24/2 (Suppl.): S81–S89 (1996) (40)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. (2003) (40)
- Time course analysis of hippocampal nerve growth factor and antioxidant enzyme activity following lateral controlled cortical impact brain injury in the rat. (2004) (40)
- The Th1 versus Th2 cytokine profile in cerebrospinal fluid after severe traumatic brain injury in infants and children (2001) (40)
- 2′,3′-cAMP, 3′-AMP, 2′-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors (2015) (39)
- Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (39)
- Cerebral resuscitation from cardiac arrest: treatment potentials. (1996) (39)
- Alterations in inducible 72‐kDa heat shock protein and the chaperone cofactor BAG‐1 in human brain after head injury (2003) (38)
- Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology (2002) (38)
- Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children (2017) (38)
- Abusive Head Trauma and Mortality–An Analysis From an International Comparative Effectiveness Study of Children With Severe Traumatic Brain Injury (2017) (38)
- Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact. (1998) (38)
- Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature rat (2012) (38)
- Role of CNPase in the oligodendrocytic extracellular 2′,3′‐cAMP‐adenosine pathway (2013) (37)
- Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury (2016) (37)
- Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. (2010) (37)
- Blood-brain barrier permeability, neutrophil accumulation and vascular adhesion molecule expression after controlled cortical impact in rats: a preliminary study. (1998) (37)
- boc-Aspartyl(OMe)-Fluoromethylketone Attenuates Mitochondrial Release of Cytochrome c and Delays Brain Tissue Loss after Traumatic Brain Injury in Rats (2007) (37)
- A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis (2019) (36)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 7. Intracranial pressure monitoring technology. (2003) (36)
- Development of the emergency preservation and resuscitation for cardiac arrest from trauma clinical trial. (2017) (36)
- Expression of the 2′,3′‐cAMP‐adenosine pathway in astrocytes and microglia (2011) (36)
- Intracranial Pressure Trajectories: A Novel Approach to Informing Severe Traumatic Brain Injury Phenotypes* (2018) (36)
- Comparison of the interleukin-6 and interleukin-10 response in children after severe traumatic brain injury or septic shock. (1997) (36)
- Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury (2017) (35)
- Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury (2017) (35)
- Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine (2017) (35)
- Increased S-Nitrosothiols and S-Nitrosoalbumin in Cerebrospinal Fluid after Severe Traumatic Brain Injury in Infants and Children: Indirect Association with Intracranial Pressure (2003) (35)
- Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model* (2006) (35)
- Extracorporeal Versus Conventional Cardiopulmonary Resuscitation After Ventricular Fibrillation Cardiac Arrest in Rats: A Feasibility Trial* (2013) (35)
- Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury (2002) (35)
- Heme Oxygenase 1 in Cerebrospinal Fluid from Infants and Children after Severe Traumatic Brain Injury (2006) (34)
- 20-HETE is Associated with Unfavorable Outcomes in Subarachnoid Hemorrhage Patients (2015) (34)
- Reliability and validity of the Pediatric Intensity Level of Therapy (PILOT) scale: A measure of the use of intracranial pressure–directed therapies (2006) (34)
- Murine orthostatic response during prolonged vertical studies: Effect on cerebral blood flow measured by arterial spin‐labeled MRI (2005) (34)
- 72-kDa heat shock protein and mRNA expression after controlled cortical impact injury with hypoxemia in rats. (1998) (34)
- Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children (2015) (34)
- Polynitroxylated-Pegylated Hemoglobin Attenuates Fluid Requirements and Brain Edema in Combined Traumatic Brain Injury Plus Hemorrhagic Shock in Mice (2013) (34)
- Phenotyping Cardiac Arrest: Bench and Bedside Characterization of Brain and Heart Injury Based on Etiology (2018) (33)
- A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. (1998) (33)
- Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids. (2012) (33)
- Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism (2011) (33)
- A brief episode of severe arterial hypertension induces delayed deterioration of brain function and worsens blood flow after transient multifocal cerebral ischemia. (1987) (33)
- Emergency preservation and resuscitation improve survival after 15 minutes of normovolemic cardiac arrest in pigs * (2007) (33)
- Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children. (2004) (33)
- Acute etomidate treatment reduces cognitive deficits and histopathology in rats with traumatic brain injury (2003) (33)
- Mri Assessment of Cerebral Blood Flow after Experimental Traumatic Brain Injury Combined with Hemorrhagic Shock in Mice (2013) (33)
- Biochemical markers of brain injury: could they be used as diagnostic adjuncts in cases of inflicted traumatic brain injury? (2004) (32)
- 20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats (2015) (32)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 18. Nutritional support. (2003) (32)
- Serum amyloid A is increased in children with abusive head trauma: a gel-based proteomic analysis (2014) (32)
- Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats. (2002) (32)
- Electron spin resonance measure of brain antioxidant activity during ischemia/reperfusion (1998) (32)
- Brief Induced Hypothermia Improves Outcome after Asphyxial Cardiopulmonary Arrest in Juvenile Rats (2005) (31)
- Critical mechanisms of secondary damage after inflicted head injury in infants and children. (2002) (31)
- Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond (2018) (31)
- Characterization of the Effects of Adenosine Receptor Agonists on Cerebral Blood Flow in Uninjured and Traumatically Injured Rat Brain using Continuous Arterial Spin-Labeled Magnetic Resonance Imaging (2005) (31)
- Mitochondrial Heat Shock Protein 60 Is Increased in Cerebrospinal Fluid following Pediatric Traumatic Brain Injury (2006) (31)
- Regionally clustered ABCC8 polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury (2018) (31)
- Intracranial Hypertension and Cerebral Hypoperfusion in Children With Severe Traumatic Brain Injury: Thresholds and Burden in Accidental and Abusive Insults (2016) (30)
- Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats. (2012) (30)
- Operation Brain Trauma Therapy: 2016 Update. (2018) (30)
- Cerebral resuscitation after traumatic brain injury and cardiopulmonary arrest in infants and children in the new millennium. (2001) (30)
- Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. (2016) (30)
- Uncoupled Cerebral Blood Flow and Metabolism after Severe Global Ischemia in Rats (1992) (30)
- Neuron-Specific Enolase and S 100 B in Cerebrospinal Fluid After Severe Traumatic Brain Injury in Infants and Children (2002) (30)
- Automated detection and characterization of SPIO‐labeled cells and capsules using magnetic field perturbations (2012) (29)
- Thalamocortical Dysfunction and Thalamic Injury after Asphyxial Cardiac Arrest in Developing Rats (2012) (29)
- Increased adrenomedullin in cerebrospinal fluid after traumatic brain injury in infants and children. (2001) (29)
- Pediatric Neurointensive Care: 2008 Update for the Rogers’ Textbook of Pediatric Intensive Care (2009) (29)
- Energy Expenditure in Children After Severe Traumatic Brain Injury (2014) (29)
- The role of autophagy in acute brain injury: A state of flux? (2019) (29)
- Regional Brain Injury on Conventional and Diffusion Weighted MRI is Associated with Outcome After Pediatric Cardiac Arrest (2013) (29)
- Up‐Regulation of Type 2 Iodothyronine Deiodinase mRNA in Reactive Astrocytes Following Traumatic Brain Injury in the Rat (1998) (29)
- Role for mammalian chitinase 3‐like protein 1 in traumatic brain injury (2015) (29)
- Extracorporeal membrane oxygenation in children. New trends. (1988) (29)
- Pediatric Traumatic Brain Injury Is Inconsistently Regionalized in the United States (2008) (28)
- Fever control and application of hypothermia using intravenous cold saline (2012) (28)
- Postcardiac arrest syndrome: focus on the brain (2009) (28)
- Moderate hypothermia may be detrimental after traumatic brain injury in fentanyl-anesthetized rats (2003) (28)
- Influence of ATP-Binding Cassette Polymorphisms on Neurological Outcome After Traumatic Brain Injury (2013) (28)
- Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65. (2015) (27)
- Polynitroxyl Albumin and Albumin Therapy after Pediatric Asphyxial Cardiac Arrest: Effects on Cerebral Blood Flow and Neurologic Outcome (2012) (27)
- Genetic disruption of cyclooxygenase‐2 does not improve histological or behavioral outcome after traumatic brain injury in mice (2008) (27)
- Glibenclamide Produces Region-Dependent Effects on Cerebral Edema in a Combined Injury Model of Traumatic Brain Injury and Hemorrhagic Shock in Mice. (2018) (27)
- Cerebral blood flow promotion after prolonged cardiac arrest. (2000) (27)
- Therapeutic hypothermia: applications in pediatric cardiac arrest. (2009) (27)
- Interleukin 6 and apolipoprotein E as predictors of acute brain dysfunction and survival in critical care patients. (2014) (27)
- A Precision Medicine Approach to Cerebral Edema and Intracranial Hypertension after Severe Traumatic Brain Injury: Quo Vadis? (2018) (27)
- Operation Brain Trauma Therapy (2012) (27)
- Hyperglycolysis is exacerbated after traumatic brain injury with fentanyl vs. isoflurane anesthesia in rats (2003) (27)
- Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury (2006) (27)
- Physical and occupational therapy utilization in a pediatric intensive care unit☆ (2017) (27)
- Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in child abuse. (2004) (26)
- A critical problem begging for new insight and new therapies. (2009) (26)
- Ischemic and traumatic brain injury: pathobiology and cellular mechanisms. (1993) (26)
- Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice. (2008) (26)
- Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. (2015) (26)
- Early Protocolized Versus Usual Care Rehabilitation for Pediatric Neurocritical Care Patients: A Randomized Controlled Trial. (2019) (26)
- Purines: forgotten mediators in traumatic brain injury (2016) (25)
- Chapter 5. Indications for intracranial pressure monitoring in pediatric patients with severe traumatic brain injury (2003) (25)
- Patterns of multiorgan dysfunction after pediatric drowning. (2015) (25)
- Extracorporeal membrane oxygenation for pediatric respiratory failure: Five‐year experience at the University of Pittsburgh (1994) (25)
- Pre-clinical models in pediatric traumatic brain injury—challenges and lessons learned (2017) (25)
- Pharmacological Inhibition of Pleckstrin Homology Domain Leucine-Rich Repeat Protein Phosphatase Is Neuroprotective: Differential Effects on Astrocytes (2013) (24)
- Therapeutic hypothermia: the Safar vision. (2009) (24)
- Emergency preservation and delayed resuscitation allows normal recovery after exsanguination cardiac arrest in rats: A feasibility trial* (2007) (24)
- Reappraisal of mouth-to-mouth ventilation during bystander-initiated CPR. (1998) (24)
- Regional TNFα mapping in the brain reveals the striatum as a neuroinflammatory target after ventricular fibrillation cardiac arrest in rats. (2010) (24)
- Mechanistic characterization of nitrite‐mediated neuroprotection after experimental cardiac arrest (2016) (24)
- Winning the cold war: inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study Group. (2007) (24)
- Effects of post‐injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies (2004) (23)
- Blood brain barrier is impermeable to solutes and permeable to water after experimental pediatric cardiac arrest (2014) (23)
- Ultrastructure of Diaschisis Lesions after Traumatic Brain Injury. (2016) (23)
- Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells (2006) (23)
- Exploratory study of serum ubiquitin carboxyl-terminal esterase L1 and glial fibrillary acidic protein for outcome prognostication after pediatric cardiac arrest. (2016) (23)
- The Nuclear Splicing Factor RNA Binding Motif 5 Promotes Caspase Activation in Human Neuronal Cells, and Increases after Traumatic Brain Injury in Mice (2015) (23)
- Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats. (2018) (23)
- No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats (2000) (23)
- Global and Regional Derangements of Cerebral Blood Flow and Diffusion Magnetic Resonance Imaging after Pediatric Cardiac Arrest. (2016) (23)
- Effect of Hyperoxia on Resuscitation of Experimental Combined Traumatic Brain Injury and Hemorrhagic Shock in Mice (2013) (23)
- Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs* (2010) (23)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 9. Use of sedation and neuromuscular blockade in the treatment of severe pediatric traumatic brain injury. (2003) (23)
- How I Cool Children in Neurocritical Care (2010) (23)
- Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI (2020) (22)
- Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report. (2000) (22)
- BrainPhys® increases neurofilament levels in CNS cultures, and facilitates investigation of axonal damage after a mechanical stretch-injury in vitro (2018) (22)
- Adenosine production by brain cells (2017) (22)
- Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats* (2009) (22)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 2: Trauma systems, pediatric trauma centers, and the neurosurgeon. (2003) (21)
- 24 vs. 72 hours of hypothermia for pediatric cardiac arrest: A pilot, randomized controlled trial. (2018) (21)
- Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1. (1999) (21)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 15. Surgical treatment of pediatric intracranial hypertension. (2003) (21)
- Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury. (2019) (21)
- Deep Hypothermia Attenuates Microglial Proliferation Independent of Neuronal Death After Prolonged Cardiac Arrest in Rats (2009) (21)
- Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion. (2016) (20)
- Hypothermia and hemostasis in severe trauma: A new crossroads workshop report (2012) (20)
- Exsanguination cardiac arrest in rats treated by 60 min, but not 75 min, emergency preservation and delayed resuscitation is associated with intact outcome. (2007) (20)
- Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. (2016) (20)
- Brain tissue oxygen monitoring identifies cortical hypoxia and thalamic hyperoxia after experimental pediatric cardiac arrest (2013) (20)
- Therapeutic hypothermia for refractory status epilepticus in a child with malignant migrating partial seizures of infancy and SCN1A mutation: a case report. (2012) (20)
- Quantification of Poly(ADP-Ribose)-Modified Proteins in Cerebrospinal Fluid from Infants and Children after Traumatic Brain Injury (2008) (20)
- Paths to Successful Translation of New Therapies for Severe Traumatic Brain Injury in the Golden Age of Traumatic Brain Injury Research: A Pittsburgh Vision. (2020) (20)
- Evaluation of autophagy using mouse models of brain injury. (2010) (20)
- Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. (2017) (20)
- Initiating Nutritional Support Before 72 Hours Is Associated With Favorable Outcome After Severe Traumatic Brain Injury in Children: A Secondary Analysis of a Randomized, Controlled Trial of Therapeutic Hypothermia (2018) (20)
- Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans. (2006) (20)
- Adenosine by aortic flush fails to augment the brain preservation effect of mild hypothermia during exsanguination cardiac arrest in dogs - an exploratory study. (2000) (19)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 10. The role of cerebrospinal fluid drainage in the treatment of severe pediatric traumatic brain injury. (2003) (19)
- Serum-Based Phospho-Neurofilament-Heavy Protein as Theranostic Biomarker in Three Models of Traumatic Brain Injury: An Operation Brain Trauma Therapy Study. (2019) (19)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 13. The use of barbiturates in the control of intracranial hypertension in severe pediatric traumatic brain injury. (2003) (19)
- Derivation and Validation of a Serum Biomarker Panel to Identify Infants With Acute Intracranial Hemorrhage (2017) (19)
- Cerebral Blood Flow Changes after Brain Injury in Human Amyloid-Beta Knock-in Mice (2013) (18)
- Cerebral microcirculatory alterations and the no-reflow phenomenon in vivo after experimental pediatric cardiac arrest (2017) (18)
- 10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat. (2000) (18)
- Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass (2017) (18)
- Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury. (2009) (18)
- Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury (2022) (18)
- PICU-Based Rehabilitation and Outcomes Assessment: A Survey of Pediatric Critical Care Physicians. (2019) (18)
- The cytochrome P450 suicide inhibitor, 1-aminobenzotriazole, sensitizes rats to zymosan-induced toxicity. (1998) (17)
- Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. (2016) (17)
- Quantitative and qualitative assessment of glymphatic flux using Evans blue albumin (2019) (17)
- Depletion of gut microbiota is associated with improved neurologic outcome following traumatic brain injury (2020) (17)
- ABCB1 Genotype is Associated with Fentanyl Requirements in Critically Ill Children (2017) (17)
- The aquaporin-4 inhibitor AER-271 blocks acute cerebral edema and improves early outcome in a pediatric model of asphyxial cardiac arrest (2018) (17)
- Chapter 19. The role of anti-seizure prophylaxis following severe pediatric traumatic brain injury (2003) (17)
- Optimization of epoxyeicosatrienoic acid syntheses to test their effects on cerebral blood flow in vivo. (1995) (17)
- Quo Vadis 2010? – Carpe Diem: Challenges and Opportunities in Pediatric Traumatic Brain Injury (2011) (16)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. (2003) (16)
- Assessment of the effect of 2‐chloroadenosine in normal rat brain using spin‐labeled MRI measurement of perfusion (2001) (16)
- No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats. (1999) (16)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 12. Use of hyperventilation in the acute management of severe pediatric traumatic brain injury. (2003) (16)
- Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa* (2018) (16)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 14. The role of temperature control following severe pediatric traumatic brain injury. (2003) (16)
- Lack of Benefit on Brain Edema, Blood-Brain Barrier Permeability, or Cognitive Outcome in Global Inducible High Mobility Group Box 1 Knockout Mice Despite Tissue Sparing after Experimental Traumatic Brain Injury. (2019) (16)
- Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation. (2008) (15)
- Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury (2011) (15)
- Effect of Short Periods of Normobaric Hyperoxia on Local Brain Tissue Oxygenation and Cerebrospinal Fluid Oxidative Stress Markers in Severe Traumatic Brain Injury (2009) (15)
- Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP. (2014) (15)
- Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients (2018) (15)
- Intraperitoneal, but not enteric, adenosine administration improves survival after volume-controlled hemorrhagic shock in rats (2001) (15)
- Pass the salt? (1998) (14)
- Development and Performance of Electronic Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction-2 Automated Acuity Scores. (2019) (14)
- Translational Stroke Research (2012) (14)
- “The British are coming”. . .and other new developments for Pediatric Critical Care Medicine (2003) (14)
- The role of adenosine during the period of delayed cerebral swelling after severe traumatic brain injury in humans. (1997) (14)
- Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review (2021) (14)
- Titrating oxygen during and after cardiopulmonary resuscitation. (2010) (14)
- Serum D-dimer concentrations are increased after pediatric traumatic brain injury. (2015) (14)
- Effect of a Single Dose of Propofol and Lack of Dextrose Administration in a Child With Mitochondrial Disease (2014) (14)
- Glibenclamide Treatment in Traumatic Brain Injury-Operation Brain Trauma Therapy. (2020) (13)
- Lack of effect of induction of hypothermia after acute brain injury. (2001) (13)
- The incredible career of Peter J. Safar, MD: the Michelangelo of acute medicine. (2004) (13)
- Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain. (1990) (13)
- Air embolism may cause unrecognized ischemia of the gray-white junction. (1988) (13)
- Important Outcomes for Parents of Critically Ill Children. (2019) (13)
- An acute inflammatory response to the use of granulocyte colony-stimulating factor to prevent infections in patients with brain injury: what about the brain? (1999) (13)
- Tackling the Challenges of Clinical Trials for Severe Traumatic Brain Injury in Children: Screening, Phenotyping, and Adapting. (2015) (13)
- Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain (2018) (13)
- Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway. (2014) (13)
- Blood-brain barrier integrity in a rat model of emergency preservation and resuscitation. (2009) (13)
- Suspended Animation for Delayed Resuscitation (1996) (13)
- Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation. (2008) (13)
- Sustained Dysbiosis and Decreased Fecal Short Chain Fatty Acids after Traumatic Brain Injury and Impact on Neurologic Outcome. (2021) (13)
- Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury. (2017) (12)
- Cerebrospinal fluid procalcitonin and severe traumatic brain injury in children (2002) (12)
- Unmasking sex-based disparity in neuronal metabolism. (2011) (12)
- Traumatic brain injury in children: Recent advances in management (2008) (12)
- Traumatic brain injury research highlights in 2015 (2016) (12)
- Prolonged deep hypothermic circulatory arrest in rats can be achieved without cognitive deficits. (2007) (12)
- Effect of Hypothermia and Targeted Temperature Management on Drug Disposition and Response Following Cardiac Arrest: A Comprehensive Review of Preclinical and Clinical Investigations. (2016) (11)
- Effect of Administration of Neuromuscular Blocking Agents in Children With Severe Traumatic Brain Injury on Acute Complication Rates and Outcomes: A Secondary Analysis From a Randomized, Controlled Trial of Therapeutic Hypothermia (2015) (11)
- Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons (2017) (11)
- Detection of brain specific cardiolipins in plasma after experimental pediatric head injury (2019) (11)
- The pharmacogenomics of severe traumatic brain injury. (2017) (11)
- Platelet-activating factor antagonists do not attenuate delayed posttraumatic cerebral edema in rats. (1991) (11)
- A new section in Pediatric Critical Care Medicine for our smallest patients (2006) (11)
- 779 (2019) (11)
- Adding insight to injury: a new era in neurotrauma (2017) (11)
- Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury* (2018) (11)
- Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats (2018) (11)
- Specialty neurointensive care--Is it just a name or a way of life? (2001) (11)
- Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 16. The use of corticosteroids in the treatment of severe pediatric traumatic brain injury. (2003) (10)
- Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice (2018) (10)
- Unusual peroxidase activity of polynitroxylated pegylated hemoglobin: Elimination of H(2)O(2) coupled with intramolecular oxidation of nitroxides. (2010) (10)
- The Many Roles of Adenosine in Traumatic Brain Injury (2013) (10)
- Reappraisal of mouth-to-mouth ventilation. (1998) (10)
- Cerebral Edema in Traumatic Brain Injury: a Historical Framework for Current Therapy (2020) (10)
- Roadmap for Advancing Pre-Clinical Science in Traumatic Brain Injury (2021) (10)
- Platelet‐ Activating Factor Receptor Blockade Decreases Early Posttraumatic Cerebral Edema in Rats (1989) (10)
- Adenovirus-mediated transfer and expression of beta-gal in injured hippocampus after traumatic brain injury in mice. (2001) (10)
- Increased adrenomedullin in cerebrospinal fluid after traumatic brain injury in children: a preliminary report. (2000) (10)
- Chapter 13. The use of barbiturates in the control of intracranial hypertension in severe pediatric traumatic brain injury (2003) (10)
- Free Fatty Acid Liberation in the Pathogenesis and Therapy of Ischemic Brain Damage (1992) (9)
- Pediatric Critical Care Medicine???Unifying our field around the world (2005) (9)
- Cerebrospinal fluid Sulfonylurea Receptor-1 is associated with intracranial pressure and outcome after pediatric TBI-an exploratory analysis of the Cool Kids Trial. (2021) (9)
- 2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway. (2019) (9)
- Chapter 5. Cerebral perfusion pressure thresholds (2012) (9)
- Robust RBM3 and β-klotho expression in developing neurons in the human brain (2019) (9)
- Nifedipine in the Treatment of a Child with Pulmonary Hypertension Associated with Severe Bronchopulmonary Dysplasia (1986) (9)
- Cardiac Arrest Induced by Asphyxia Versus Ventricular Fibrillation Elicits Comparable Early Changes in Cytokine Levels in the Rat Brain, Heart, and Serum (2021) (9)
- Gut damage during hemorrhagic shock: effects on survival of oral or enteral interleukin-6. (2001) (9)
- Pediatrie traumatic brain injury: Beyond the guidelines (2005) (9)
- Intracranial and Cerebral Perfusion Pressure Thresholds Associated With Inhospital Mortality Across Pediatric Neurocritical Care. (2020) (9)
- CSF lipocalin-2 increases early in subarachnoid hemorrhage are associated with neuroinflammation and unfavorable outcome (2021) (9)
- Assessment of 2-chloroadenosine treatment after experimental traumatic brain injury in the rat using arterial spin-labeled MRI: a preliminary report. (2000) (9)
- Chapter 11. Use of hyperosmolar therapy in the management of severe pediatric traumatic brain injury (2003) (9)
- Chapter 9. Use of sedation and neuromuscular blockade in the treatment of severe pediatric traumatic brain injury (2003) (8)
- Chapter 2. Methods (2012) (8)
- Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest. (2020) (8)
- Chapter 3. Indications for intracranial pressure monitoring (2012) (8)
- It might be time to let cooler heads prevail after mild traumatic brain injury or concussion (2015) (8)
- Enduring Disturbances in Regional Cerebral Blood Flow and Brain Oxygenation at 24 Hours after Asphyxial Cardiac Arrest in Developing Rats (2016) (8)
- The Brain and Hypothermia—From Aristotle to Targeted Temperature Management (2017) (8)
- Chapter 4. Threshold for treatment of intracranial hypertension (2012) (8)
- Systemic Estrone Production and Injury-Induced Sex Hormone Steroidogenesis after Severe Traumatic Brain Injury: A Prognostic Indicator of Traumatic Brain Injury-Related Mortality. (2018) (8)
- In response to comments on IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study (2014) (8)
- Chapter 17. Critical pathway for the treatment of established intracranial hypertension in pediatric traumatic brain injury (2003) (8)
- Chapter 12. Use of hyperventilation in the acute management of severe pediatric traumatic brain injury (2003) (7)
- Assessment of Dynamic Intracranial Compliance in Children with Severe Traumatic Brain Injury: Proof-of-Concept (2020) (7)
- Unique brain region-dependent cytokine signatures after prolonged hypothermic cardiac arrest in rats. (2015) (7)
- ENDOTHELIN-1 IS INCREASED IN CEREBROSPINAL FLUID FOLLOWING TRAUMATIC BRAIN INJURY IN CHILDREN (1999) (7)
- Ventricular fibrillation cardiac arrest produces a chronic striatal hyperdopaminergic state that is worsened by methylphenidate treatment (2017) (7)
- Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury (2022) (7)
- Effect of Phorbol Myristate Acetate on Cerebral Blood Flow in Normal and Neutrophil‐Depleted Rats (1993) (7)
- Chapter 8. Cerebral perfusion pressure (2003) (7)
- Bakken Lecture: The brain, the heart, and therapeutic hypothermia (2009) (7)
- Combined Neurotrauma Models: Experimental Models Combining Traumatic Brain Injury and Secondary Insults. (2016) (7)
- Factors Contributing to Fentanyl Pharmacokinetic Variability Among Diagnostically Diverse Critically Ill Children (2019) (7)
- Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury (2021) (7)
- Operation Brain Trauma Therapy: Simvastatin Treatment in Traumatic Brain Injury (2016) (7)
- Pathobiology of Blast Injury (2007) (7)
- A high-throughput screening assay of ascorbate in brain samples (2011) (7)
- Management of pulmonary barotrauma by extracorporeal membrane oxygenation, apnea, and lung rest. (1988) (7)
- Textbook of Critical Care, 6th Edition Expert Consult Premium Edition - Enhanced Online Features and Print (2011) (7)
- Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. (2012) (7)
- ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury. (2018) (6)
- 23: EFFECT OF THE NOVEL AQUAPORIN-4 ANTAGONIST AER-271 IN COMBINED TBI PLUS HEMORRHAGIC SHOCK IN MICE (2015) (6)
- RNA Binding Motif 5 (RBM5) in the CNS—Moving Beyond Cancer to Harness RNA Splicing to Mitigate the Consequences of Brain Injury (2020) (6)
- Decreased DNA Methylation of RGMA is Associated with Intracranial Hypertension After Severe Traumatic Brain Injury: An Exploratory Epigenome-Wide Association Study (2022) (6)
- Chapter 61 – Severe Traumatic Brain Injury in Infants and Children (2011) (6)
- Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference (2021) (6)
- Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children (2021) (6)
- Chapter 13. Hyperventilation (2012) (6)
- A tribute to Peter J. Safar, MD (2003) (6)
- Bioactive Oxylipins in Infants and Children With Congenital Heart Disease Undergoing Pediatric Cardiopulmonary Bypass (2020) (6)
- PCCM moves to online-only publication of case reports (2008) (6)
- Making an IMPACT in traumatic brain injury research (2013) (6)
- Therapeutic Hypothermia on Its 10th Anniversary: Is it Time to Turn the Thermostat Down? (2012) (6)
- Minocycline fails to improve neurologic and histologic outcome after ventricular fibrillation cardiac arrest in rats (2019) (6)
- Oxidative stress induces release of 2’-AMP from microglia (2019) (6)
- Serum Biomarkers of Regeneration and Plasticity are Associated with Functional Outcome in Pediatric Neurocritical Illness: An Exploratory Study (2021) (5)
- Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats (2017) (5)
- Chapter 107 – Severe Traumatic Brain Injury in Infants and Children (2006) (5)
- Perfusion MRI assessment of cerebral blood flow and CO2 reactivity after controlled cortical impact in rats. (1997) (5)
- Polynitroxylated Pegylated Hemoglobin-A Novel, Small Volume Therapeutic for Traumatic Brain Injury Resuscitation: Comparison to Whole Blood and Dose Response Evaluation. (2017) (5)
- CEREBROSPINAL FLUID ADENOSINE AND CEREBRAL BLOOD FLOW AND METABOLISM AFTER HUMAN HEAD INJURY. (1995) (5)
- Early Axonal Injury and Delayed Cytotoxic Cerebral Edema are Associated With Microglial Activation in a Mouse Model of Sepsis. (2019) (5)
- SOLUBLE FAS IS INCREASED IN CSF FROM INFANTS AND CHILDREN AFTER HEAD INJURY (1999) (5)
- Serum Biomarkers of Regeneration and Plasticity are Associated with Functional Outcome in Pediatric Neurocritical Illness: An Exploratory Study (2021) (5)
- Titrating the Dose of Oxygen after Severe Traumatic Brain Injury in the Era of Precision Medicine. (2017) (5)
- Hypothermia Decreases Cerebrospinal Fluid Asymmetric Dimethylarginine Levels in Children With Traumatic Brain Injury (2013) (5)
- Subarachnoid hemorrhage, systemic immune response syndrome, and MODS: is there cross-talk between the injured brain and the extra-cerebral organ systems? Multiple organ dysfunction syndrome. (1999) (5)
- Photochemistry of 2-methylcyclododecanone. (1977) (5)
- Textbook of critical care (2018) (5)
- Novel pharmacologic approaches to brain resuscitation after cardiorespiratory arrest in the pediatric patient. (1988) (5)
- INTERLEUKIN-8 IS INCREASED IN CSF OF CHILDREN WITH SEVERE TRAUMATIC BRAIN INJURY (1998) (5)
- Chapter 10. The role of cerebrospinal fluid drainage in the treatment of severe pediatric traumatic brain injury (2003) (4)
- Association Between Hyperoxemia and Increased Cell-Free Plasma Hemoglobin During Cardiopulmonary Bypass in Infants and Children. (2021) (4)
- Neurological Complications Acquired During Pediatric Critical Illness: Exploratory “Mixed Graphical Modeling” Analysis Using Serum Biomarker Levels (2021) (4)
- Guiding Pediatric Critical Care Medicine Toward a Bigger "Impression" in 2017 and Beyond. (2017) (4)
- 819: PILOT RCT OF EARLY VERSUS USUAL CARE REHABILITATION IN PEDIATRIC NEUROCRITICAL CARE (2018) (4)
- Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study (2022) (4)
- It Seems Like the Resuscitation Happened Ages Ago-Chronic Critical Illness in Children: Digging in for the Long Haul. (2015) (4)
- Personalising Outcomes after Child Cardiac Arrest (POCCA): design and recruitment challenges of a multicentre, observational study (2020) (4)
- The regional cerebral blood flow response to cortical microelectrode insertion is neutrophil dependent. (1992) (4)
- Leukotrienes, Prostaglandins, and Granulocyte Accumulation in Cerebral Ischemia (1987) (4)
- CEREBROSPINAL FLUID PROCALCITONIN IS INCREASED AFTER TRAUMATIC BRAIN INJURY IN CHILDREN (1999) (4)
- Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P 450 Drug Metabolism (2011) (4)
- Identification of Novel Targets of RBM5 in the Healthy and Injured Brain (2020) (4)
- Current and future therapies of pediatric cardiopulmonary arrest (2008) (4)
- Cardiopulmonary resuscitation by chest compression alone. (2000) (4)
- Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies (2015) (4)
- Chapter 8. Hyperosmolar therapy (2012) (4)
- An Exploratory Assessment of Serum Biomarkers of Post-Cardiac Arrest Syndrome in Children. (2021) (4)
- Cell Signaling: Serine/Threonine Protein Kinases and Traumatic Brain Injury (2001) (4)
- Pathobiology of Secondary Brain Injury (2012) (4)
- THERAPEUTIC HYPOTHERMIA ATTENUATES OXIDATIVE STRESS AFTER TRAUMATIC BRAIN INJURY IN INFANTS AND CHILDREN: 27 (2002) (4)
- Recombinant Octameric Hemoglobins as Resuscitation Fluids in a Murine Model of Traumatic Brain Injury Plus Hemorrhagic Shock (2013) (4)
- Physiological assessment and control in studies evaluating central nervous system injury: should size matter? (2006) (4)
- QUTNOLINIC ACID IN CEREBROSPINAL FLUID OF CHILDREN AFTER TRAUMATIC BRAIN INJURY: A PRELIMINARY REPORT (1998) (4)
- New Developments for Pediatric Critical Care Medicine in 2019 and Beyond. (2019) (4)
- Partial liquid ventilation combined with high frequency gas ventilation: clinical breakthrough or two treatments looking for a home? (1999) (4)
- Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications (2019) (4)
- Presenting predictors and temporal trends of treatment‐related outcomes in diabetic ketoacidosis (2018) (4)
- Association between pediatric TBI mortality and median family income in the United States: A retrospective cohort study (2022) (4)
- Photochemistry of 2-methylcycloalkanones (1977) (4)
- Operation Brain Trauma Therapy: An Exploratory Study of Levetiracetam Treatment Following Mild Traumatic Brain Injury in the Micro Pig (2021) (4)
- Should we add stem cells to the code cart in resuscitation of heatstroke? (2005) (3)
- Concluding comments and suggestions for young resuscitation researchers. (1996) (3)
- Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest. (2019) (3)
- Developing cooling strategies targeting the heart in adults and children. (2012) (3)
- Pediatric Critical Care Medicine, our expanding global mission. (2001) (3)
- EARLY GRANULOCYTE ACCUMULATION AND EDEMA AFTER CEREBRAL TRAUMA (1989) (3)
- MANIPULATING SYSTEMIC NEUTROPHIL COUNT IN EXPERIMENTAL CEREBRAL CONTUSION IN RATS: EFFECTS ON BLOOD-BRAIN BARRIER DAMAGE AND EDEMA (1999) (3)
- Pediatric Critical Care Medicine 2016: Growth and Further Specialization. (2016) (3)
- HYPOTHERMIA REDUCES ACUTE INFLAMMATION AFTER TRAUMATIC BRAIN INJURY IN RATS† 317 (1996) (3)
- Temporal and Spatial Changes in the Microbiome Following Pediatric Severe Traumatic Brain Injury. (2022) (3)
- Strategic Planning for Research in Pediatric Critical Care (2016) (3)
- Secondary Changes After Injury and Temperature. (2016) (3)
- Schwann Cells Metabolize Extracellular 2′,3′-cAMP to 2′-AMP (2015) (3)
- Chapter 3. Prehospital airway management (2003) (3)
- Relationship Between Increases in Pancreatic Enzymes and Cerebral Events in Children After Traumatic Brain Injury (2009) (3)
- Chapter 9. Temperature control (2012) (3)
- Novel Potentials for Emergency Hypothermia: Suspended Animation with Delayed Resuscitation from Exsanguination Cardiac Arrest (2004) (3)
- Neurologic Emergencies and Stabilization (2011) (3)
- Traumatic Brain Injury: Laboratory Studies (2005) (3)
- 31: INTRACRANIAL PRESSURE TRAJECTORIES A NOVEL TOOL TO INFORM SEVERE TBI PHENOTYPES (2018) (3)
- Funding resuscitation research. (1996) (3)
- Targeting therapeutic hypothermia in neonatal resuscitation and beyond: it is time to phenotype. (2014) (3)
- Pediatric Critical Care Medicine: re-tooling to accommodate growth and success while preserving excellence. (2011) (3)
- Chapter 14. The role of temperature control following severe pediatric traumatic brain injury (2003) (3)
- Chapter 58 – Hypoxic-Ischemic Encephalopathy: Pathobiology and Therapy of the Postresuscitation Syndrome in Children (2006) (3)
- Role of CD73 in renal sympathetic neurotransmission in the mouse kidney (2013) (3)
- Abcc8 (Sulfonylurea Receptor-1) Impact on Brain Atrophy after TBI Varies by Sex. (2021) (3)
- Epigenetic Effects on Pediatric Traumatic Brain Injury Recovery (EETR): An Observational, Prospective, Longitudinal Concurrent Cohort Study Protocol (2020) (3)
- DNA DAMAGE IS TEMPERATURE DEPENDENT EARLY AFTER TRAUMATIC BRAIN INJURY IN RATS (1999) (3)
- The brain, the heart, and therapeutic hypothermia (2009) (2)
- Comprar Textbook of Critical Care, 6th Edition Expert Consult Premium Edition - Enhanced Online Features and Print | Mitchell P. Fink | 9781437713671 | Saunders (2011) (2)
- Pediatric Traumatic Brain Injury: Using serum biomarkers to diagnose, assess, treat, and predict outcome after pediatric TBI (2010) (2)
- Letters to the Editor (multiple letters) [1] (1998) (2)
- Cardiopulmonary Resuscitation and Rescue Therapies (2021) (2)
- HBO: It's not ready for prime time for the treatment of acute central nervous system trauma. (2001) (2)
- Platelet activating factor antagonists do not alter normal cerebral blood flow or cerebral oxygen consumption. (1990) (2)
- 18: IN VIVO METABOLIC AND STRUCTURAL IMAGING AT 7T AFTER MILD TRAUMATIC BRAIN INJURY IN IMMATURE RATS (2015) (2)
- Opioid e-prescribing trends at discharge in a large pediatric health system. (2019) (2)
- Hypothermic therapies targeting brain and spinal cord injury. Introduction. (2009) (2)
- Further growth and development for Pediatric Critical Care Medicine (2004) (2)
- POLY-ADP-RIBOSYLATION AS A POST-TRANSLATIONAL MODIFICATION OF MITOCHONDRIAL PROTEINS: 82 (2004) (2)
- Chapter 16. Glucose and nutrition (2012) (2)
- How low can you go? Blood pressure control after intracranial hemorrhage. (1999) (2)
- International Survey of Critically Ill Children With Acute Neurologic Insults: The PANGEA study (2017) (2)
- Chapter 1. Introduction (2012) (2)
- Clinical Deterioration and Neurocritical Care Utilization in Pediatric Patients With Glasgow Coma Scale Score of 9-13 After Traumatic Brain Injury: Associations With Patient and Injury Characteristics. (2021) (2)
- Chapter 12. Decompressive craniectomy for the treatment of intracranial hypertension (2012) (2)
- Pre-Hospital Whole Blood Resuscitation Reduces Fluid Requirement While Maintaining Critical Physiology in a Model of Penetrating Traumatic Brain Injury and Hemorrhage: Implications on Resource-Limited Combat Casualty Care. (2020) (2)
- Biochemical, Metabolic, and Molecular Responses in the Brain After Inflicted Childhood Neurotrauma (2003) (2)
- Asphyxial cardiac arrest from drowning: giving E-CPR the cold shoulder. (2015) (2)
- WHAT ARE THE KEY MECHANISMS OF SECONDARY DAMAGE AFTER TRAUMATIC BRAIN INJURY?: 16 (1999) (2)
- Biochemical and Molecular Mechanisms after Severe Traumatic Brain Injury in Children (2002) (2)
- 738: ABCC8 TAG SINGLE NUCLEOTIDE POLYMORPHISMS CORRELATE WITH EDEMA AND OUTCOME IN TRAUMATIC BRAIN INJURY (2016) (2)
- Resuscitation of Experimental Traumatic Brain Injury and Hemorrhagic Shock in Mice: Acute Effects of Polynitroxylated Pegylated Hemoglobin and 100% Oxygen (2010) (2)
- COMBINATION CYCLOOXYGENASE-LIPOXYGENASE INHIBITION IN THE RESUSCITATION FROM FOCAL BRAIN ISCHEMIA IN DOGS USING BW 755C, PROSTACYCLIN, AND HEPARIN (1985) (2)
- International traumatic brain injury research: an annus mirabilis? (2019) (2)
- Chapter 16. The use of corticosteroids in the treatment of severe pediatric traumatic brain injury (2003) (2)
- Improving outcomes from resuscitation: from hypertension and hemodilution to therapeutic hypothermia to H2. (2014) (2)
- EFFECT OF HEMORRHAGIC SHOCK ON CEREBRAL BLOOD FLOW IN EXPERIMENTAL TRAUMATIC BRAIN INJURY: MAGNETIC RESONANCE IMAGING ASSESSMENT.: 17 (2006) (2)
- Intracranial monitoring and continuous data collection. (2012) (2)
- The Presence of Anemia in Children with Abusive Head Trauma. (2020) (2)
- ADENOSINE BY AORTIC FLUSH FAILS TO AUGMENT THE BRAIN PRESERVATION EFFECT OF MILD HYPOTHERMIA DURING EXSANGUINATION CARDIAC ARREST IN DOGS (1999) (2)
- A Perfect Tribute to the Tremendous Academic Growth of Pediatric Critical Care Medicine in Turkey. (2020) (2)
- Barriers to Drug Delivery for Brain Trauma (2014) (2)
- Platelet-activating factor receptor blockade decreases early post-traumatic cerebral edema in rats (1988) (2)
- Sulfonylurea Receptor-1 as a Novel Biomarker for Cerebral Edema in Patients with Severe Traumatic Brain Injury (I11.005) (2016) (2)
- Inflammatory Process in the Pathobiology of Secondary Damage After Traumatic Brain Injury (1997) (2)
- Chapter 15. Analgesics, sedatives, and neuromuscular blockade (2012) (2)
- Increased adenosine concentration in cerebrospinal fluid after severe traumatic brain injury in infants and children: Association with severity of injury (1999) (2)
- Reappraisal of Mouth-to-Mouth Ventilation. (1998) (2)
- EFFECT OF sCR-1 ON BRAIN POLYMORPHONUCLEAR LEUKOCYTE ACCUMULATION AFTER BRAIN INJURY IN RATS (1994) (2)
- The benefits of youth are lost on the young cardiac arrest patient (2017) (2)
- “Take a Number”—Precision Monitoring Directs Precision Therapy (2020) (2)
- Chapter 7. Neuroimaging (2012) (2)
- Resuscitation with epinephrine worsens cerebral capillary no-reflow after experimental pediatric cardiac arrest: An in vivo multiphoton microscopy evaluation (2022) (2)
- A "Metamorphosis" in Our Approach to Treatment Is Not Likely to Result From a Meta-Analysis of the Use of Therapeutic Hypothermia in Severe Traumatic Brain Injury. (2017) (2)
- 718: AQUAPORIN-4 INHIBITOR AER-271 BLOCKS EARLY CEREBRAL EDEMA IN PEDIATRIC RAT ASPHYXIAL CARDIAC ARREST (2016) (2)
- Chapter 11. Barbiturates (2012) (2)
- Neurostimulant Prescribing Patterns in Children Admitted to the Intensive Care Unit after Traumatic Brain Injury. (2019) (2)
- Choice of Whole Blood versus Lactated Ringers Resuscitation Modifies the Relationship Between Blood Pressure Target and Functional Outcome after Traumatic Brain Injury Plus Hemorrhagic Shock in Mice. (2021) (2)
- Chapter 7. Intracranial pressure monitoring technology (2003) (2)
- NEUTROPENIA DOES NOT PREVENT POST- TRAUMATIC CEREBRAL EDEMA (1990) (1)
- ESTABLISHMENT OF A RAT MODEL OF SUSPENDED ANIMATION WITH DELAYED RESUSCITATION: A PRELIMINARY REPORT: 211 (2004) (1)
- 690: DYNAMIC ASSESSMENT OF INTRACRANIAL COMPLIANCE IN PEDIATRIC TRAUMATIC BRAIN INJURY: PROOF OF CONCEPT (2020) (1)
- Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest (2022) (1)
- 17: EARLY NUTRITIONAL SUPPORT IS ASSOCIATED WITH FAVORABLE OUTCOME IN PEDIATRIC TRAUMATIC BRAIN INJURY (2015) (1)
- Strengthening the link between pre-clinical and clinical resuscitation research. (2020) (1)
- Pediatric Critical Care Medicine reaches another milestone. Foreword. (2012) (1)
- 13: AUTOPHAGY BIOMARKERS BECLIN 1 AND P62 ARE DETECTABLE IN CEREBROSPINAL FLUID AFTER TBI IN CHILDREN (2013) (1)
- Factors associated with hospital admission following traumatic brain injury and infectious encephalopathy in children in four resource limited settings (2018) (1)
- PRELIMINARY EVALUATION OF SIMBABY, A NOVEL PEDIATRIC SIMULATOR: 229 (2004) (1)
- Optimizing oxygenation and ventilation after cardiac arrest in "little adults". (2012) (1)
- POSTTRAUMATIC HYPOTHERMIA DECREASES MORTALITY AFTER SEVERE CONTROLLED CORTICAL IMPACT IN RATS. (1995) (1)
- 729: Whole Brain Diffusion Tensor Imaging Analysis and Outcomes Following Pediatric Cardiac Arrest (2020) (1)
- INCREASED ADRENOMEDULLIN IN CEREBROSPINAL FLUID AFTER TRAUMATIC BRAIN INJURY IN CHILDREN: A PRELIMINARY REPORT (1999) (1)
- Letter: Evolution and Impact of the Brain Trauma Foundation Guidelines. (2022) (1)
- INTERSTITIAL BRAIN ADENOSINE DURING JUGULAR VENOUS DESATURATIONS AFTER HUMAN TRAUMATIC BRAIN INJURY (TBI): EVIDENCE OF ENERGY FAILURE (1998) (1)
- Abstract 178: Regional and Temporal Brain Tissue Cytokine Profile After Prolonged Hypothermic Cardiac Arrest in Rats: A Novel Role for Striatum (2010) (1)
- Cerebral Resuscitation and Traumatic Brain Injury (2012) (1)
- 32: PHENYTOIN CONCENTRATIONS ARE ELEVATED IN CHILDREN RECEIVING THERAPEUTIC HYPOTHERMIA FOLLOWING TRAUMATIC BRAIN INJURY. (2012) (1)
- 785: TRPM-4 SINGLE-NUCLEOTIDE POLYMORPHISMS CORRELATE WITH CEREBRAL EDEMA IN TRAUMATIC BRAIN INJURY (2018) (1)
- Limbic Pathway Vulnerability Associates with Neurologic Outcome in Children After Cardiac Arrest. (2022) (1)
- IS THE MANAGEMENT OF SEVERE TBI IN CHILDREN IN THE US APPROPRIATELY REGIONALIZED?: 51 (2002) (1)
- 62 – Is Hypothermia Useful in Managing Critically Ill Patients? Which Ones? Under What Conditions? (2010) (1)
- Lack of Benefit on Brain Edema, Blood–Brain Barrier Permeability, or Cognitive Outcome in Global Inducible High Mobility Group Box 1 Knockout Mice Despite Tissue Sparing after Experimental Traumatic Brain Injury (2018) (1)
- Healthcare Use in the Year Following Bronchiolitis Hospitalization. (2022) (1)
- Cancer 4-1-2015 Detection of PHLPP 1 α / β in Human and Mouse Brain by Different Anti-PHLPP 1 Antibodies (2018) (1)
- THE MULTIFACETED ROLE OF ADENOSINE IN EXPERIMENTAL AND CLINICAL TRAUMATIC BRAIN INJURY (2001) (1)
- Survival Rates After Pediatric Traumatic Out-of-Hospital Cardiac Arrest Suggest an Underappreciated Therapeutic Opportunity (2022) (1)
- Temporal Patterns in Brain Tissue and Systemic Oxygenation Associated with Mortality After Severe Traumatic Brain Injury in Children (2022) (1)
- Hidden Perils of the "Wild Blue Yonder" after Traumatic Brain Injury. (2016) (1)
- 880: ARDA2A AND CYP3A5 GENOTYPES ARE ASSOCIATED WITH FENTANYL REQUIREMENTS IN CRITICALLY ILL CHILDREN (2018) (1)
- In quest of the optimal cooling device: isn't faster "too fast"? (2008) (1)
- 491: GLIBENCLAMIDE REDUCES DIFFUSE CEREBRAL EDEMA IN A COMBINED MODEL OF TRAUMATIC BRAIN INJURY AND SHOCK (2015) (1)
- Duration of therapeutic hypothermia or targeted temperature management in pediatric cardiac arrest: Seeing through the ice. (2018) (1)
- Hypothermia therapy after traumatic brain injury in children. (2008) (1)
- Caution Should be Exercised When Maintaining a Serum Sodium Level >160 meq/L: The authors reply (2004) (1)
- Introduction to the Proceedings of the Second Annual Safar Symposium (2004) (1)
- A special supplement for a very special man: A celebration of the life of Peter J. Safar, MD (2004) (1)
- Multifaceted Benefit of Whole Blood Versus Lactated Ringer’s Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice (2020) (1)
- A NOVEL METHOD FOR QUANTIFICATION OF POLY(ADPRIBOSE)-MODIFIED PROTEINS VALIDATED IN CEREBROSPINAL FLUID FROM INFANTS AND CHILDREN AFTER TRAUMATIC BRAIN INJURY.: 29 (2005) (1)
- 818: SERUM BIOMARKER RELATIONSHIPS WITH FUNCTIONAL IMPAIRMENT FOLLOWING ACUTE PEDIATRIC BRAIN INJURY (2018) (1)
- Poly(ADP-Ribose)synthetase activation and NAD depletion after traumatic brain injury in rats (1999) (1)
- Hypoxia–ischemia-mediated effects on neurodevelopmentally regulated cold-shock proteins in neonatal mice under strict temperature control (2022) (1)
- Temperature management in neurological and neurosurgical intensive care units. (2013) (1)
- Chapter 62 – Hypoxic-Ischemic Encephalopathy: Pathobiology and Therapy of the Post-Resuscitation Syndrome in Children (2011) (1)
- Animal Models of Traumatic Brain Injury (2011) (1)
- &ggr;-GLUTAMYLCYSTEINE ETHYL ESTER INCREASES BRAIN GLUTATHIONE AFTER ASPHYXIAL CARDIAC ARREST IN POST-NATAL DAY 17 RATS: 86 (2004) (1)
- 12: POLYNITROXYLATED-PEGYLATED HEMOGLOBIN AS AN ULTRA-SMALL VOLUME RESUSCITATION THERAPY (2015) (1)
- Is the administration of inhaled nitric oxide (NO) associated with electroencephalogram abnormalities? There is NO harm in looking. (1998) (1)
- Chapter 14. Corticosteroids (2012) (1)
- Association of EEG and Blood-Based Brain Injury Biomarker Accuracy to Prognosticate Mortality After Pediatric Cardiac Arrest: An Exploratory Study. (2022) (1)
- SUSPENDED ANIMATION WITH DELAYED RESUSCITATION ALLOWS INTACT SURVIVAL FROM CARDIAC ARREST RESULTING FROM PROLONGED LETHAL HEMORRHAGE IN DOGS: 81 (2004) (1)
- Temperature management in neurological and neurosurgical intensive care units. (2013) (1)
- The Safar Center for Resuscitation Research: Searching for Breakthroughs in the New Millennium (2006) (1)
- Molecular pathophysiology in critical care illness (1993) (1)
- Abstract 199: TNF-Alpha Response After Experimental Cardiac Arrest in Rats is Not Attenuated by Thalidomide (2019) (1)
- Neurological sequelae of pH1N1 influenza in children: A case series observed during a pandemic* (2010) (1)
- Show us the evidence? An Evidence-Based Journal Club linking PedsCCM: The Pediatric Critical Care Web Site and Pediatric Critical Care Medicine (2005) (1)
- MECHANISMS OF TYROSINE NITRATION OF MNSOD AFTER TRAUMATIC BRAIN INJURY.: 61 (2005) (1)
- Chapter 6. Advanced neuromonitoring (2012) (1)
- O020 / #442: POST PEDIATRIC NEUROCRITICAL CARE RECOVERY: A WHOLE CHILD AND FAMILY PERSPECTIVE (2021) (1)
- Breaking Into the Top Ten. (2017) (1)
- Chapter 10. Cerebrospinal fluid drainage (2012) (1)
- MAGNETIC RESONANCE IMAGING ASSESSMENT OF MACROPHAGE ACCUMULATION IN MOUSE BRAIN AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY: A PRELIMINARY REPORT.: 24 (2006) (1)
- Central Nervous System Injury and Temperature Management. (2016) (1)
- Authors’ Response to Letter to the Editor, “Effect of a single dose of propofol and lack of dextrose administration in a child with mitochondrial disease – A Case Report” (2014) (1)
- Smiling on the Bright Future of Pediatric Critical Care Medicine and the "Task(er)" at Hand. (2020) (1)
- Abstract 14775: Regional TNF{alpha} Mapping in the Brain reveals the Striatum as a Neuroinflammatory Target after Ventricular Fibrillation Cardiac Arrest in Rats (2010) (1)
- Chapter 17. Antiseizure prophylaxis (2012) (1)
- Kollidon VA64 Treatment in Traumatic Brain Injury, Operation Brain Trauma Therapy. (2021) (1)
- 1807: PATTERNS OF MULTIPLE ORGAN DYSFUNCTION IN ABUSIVE HEAD TRAUMA (2019) (0)
- 255: SERUM CYTOCHROME C IS ASSOCIATED WITH OUTCOME AND CARDIAC DYSFUNCTION AFTER PEDIATRIC CARDIAC ARREST (2014) (0)
- 1535 (2019) (0)
- Biochemical, Cellular, and Molecular Mechanisms of Neuronal Death and Secondary Brain Injury in Critical Care (2011) (0)
- 186: EXPLORATORY STUDY OF DURATION OF HYPOTHERMIA FOR NEUROPROTECTION AFTER PEDIATRIC CARDIAC ARREST (2015) (0)
- Brain Oral Session: Traumatic Brain Injury—Metabolism (2009) (0)
- Assessment of the Effect of Different Resuscitation Fluids on Cerebral Blood Flow and Edema Following Experimental Traumatic Brain Injury and Hemorrhagic Shock in Mice (2010) (0)
- 835: IDENTIFYING CAUSAL RELATIONSHIPS BETWEEN ICP AND INTENSITY OF MEDICAL THERAPIES IN PEDIATRIC TBI (2021) (0)
- Novel Nitroxide Resuscitation Strategies in Experimental Traumatic Brain Injury (2010) (0)
- Chapter 18. Nutritional support (2003) (0)
- NEUTROPHILS CONTRIBUTE TO POSTTRAUMATIC HYPEREMIA IN RAT BRAIN (1993) (0)
- PNPH, A Neuroprotectant HBOC: Studies of in Vivo and in Vitro Traumatic Brain Injury (2009) (0)
- Abstract 154: Serum Biomarkers of Brain Injury Predict Outcome After Pediatric Cardiac Arrest (2011) (0)
- 1691: AXONAL INJURY, CYTOTOXIC CEREBRAL EDEMA, AND MICROGLIAL ACTIVATION IN A MOUSE MODEL OF SEPSIS (2020) (0)
- Progress amidst some anticipated growing pains for PCCM. (2013) (0)
- BROAD SPECTRUM ANTI-PLATELET AGGREGATION THERAPY IMPROVES POSTISCHEMIC CEREBRAL BLOOD FLOW (CBF) AND CORTICAL SOMATOSENSORY EVOKED RESPONSE (CSER) RECOVERY, BUT FAILS TO BLOCK PLATELET ACCUMULATION IN THE DAMAGED HEMISPHERE (1987) (0)
- Intracranial Pressure (ICP) Trajectories: a Novel Tool that may Inform Outcome and Mortality in Severe Traumatic Brain Injury (P4.299) (2018) (0)
- PHLPP Inhibitor NSC74429 Is Neuroprotective in Rodent Models of Cardiac Arrest and Traumatic Brain Injury (2022) (0)
- NITRATION AND INACTIVATION OF MNSOD AFTER EXPERIMENTAL CNS INJURY: STUDIES IN EXPERIMENTAL TRAUMATIC BRAIN INJURY AND NEURONAL CULTURE: 87 (2004) (0)
- APOPTOSIS-SUPPRESSOR PROTEIN bcl-2 IS INCREASED IN CEREBROSPINAL FLUID IN CHILDREN SURVIVING TRAUMATIC BRAIN INJURY (1998) (0)
- EFFECT OF A DELTA-OPIOID AGONIST IN A RAT MODEL OF LETHAL HEMORRHAGE TREATED BY EMERGENCY PRESERVATION AND RESUSCITATION.: 409 (2006) (0)
- Pediatric critical care medicine. (2016) (0)
- PHOTOCHEMISTRY OF 2-METHYLCYCLODODECANONE (1977) (0)
- 382: UNDERSTANDING THE BURDEN OF INTRACRANIAL HYPERTENSION AND CEREBRAL HYPOPERFUSION IN PEDIATRIC TRAUMATIC BRAIN INJURY (TBI) – A PRELIMINARY ANALYSIS (2012) (0)
- 9: RENAL INJURY ASSOCIATED WITH FREE HEMOGLOBIN IN RAT CARDIOPULMONARY BYPASS IS ATTENUATED BY NITRITE (2015) (0)
- Mass critical care for children: implications for adult critical care. (2011) (0)
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- Ascorbate Deficiency Confers Resistance to Hippocampal Neurodegeneration after Asphyxial Cardiac Arrest in Juvenile Rats (2021) (0)
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- THE EFFECT OF INTRAPARENCHYMAL INJECTION OF ACTIVATED GRANULOCYTES ON DELAYED CEREBRAL EDEMA IN RATS (1990) (0)
- Resuscitative Moderate Hypothermia for Severe Traumatic Brain Injury (1997) (0)
- Severe traumatic brain injury (2008) (0)
- INDUCIBLE 72kd HEAT SHOCK PROTEIN IS INCREASED AFTER TRAUMATIC BRAIN INJURY IN HUMANS: EVIDENCE FOR THE STRESS RESPONSE (1999) (0)
- HYPOTHERMIA FAILS TO REDUCE LESION VOLUME AFTER TRAUMATIC BRAIN INJURY IN IMMATURE RATS (1994) (0)
- A special thanks to our friends and colleagues in Japan (2006) (0)
- BW 755C PRFTREATMENT FAILS TO INHIBIT EARLY GRANULOCYTE ACCUMULATION AFTER FOCAL BRAIN ISCHEMIA (1986) (0)
- Reviewer Thank You. (2021) (0)
- 1235: ABBCC8 (SULFONYLUREA RECEPTOR 1) KO CONFERS NEUROPROTECTION IN SEPSIS-ASSOCIATED BRAIN INJURY (2022) (0)
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- Second Annual Safar Symposium (2005) (0)
- 61: TEMPORAL PATTERNS IN BRAIN TISSUE OXYGENATION ASSOCIATED WITH MORTALITY AFTER SEVERE TBI IN CHILDREN (2021) (0)
- 366: COST ANALYSIS OF THE PANGEA STUDY (2014) (0)
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- 1448: RARE TRMP4 AND ABCC8 VARIANTS ASSOCIATED WITH DECREASED INCIDENCE OF CNS FAILURE IN PEDIATRIC SEPSIS (2021) (0)
- 865: FEASIBILITY OF A MUSIC THERAPY INTERVENTION IN THE PEDIATRIC INTENSIVE CARE UNIT (2021) (0)
- Serum levels of the cold stress hormones FGF21 and GDF-15 after cardiac arrest in infants and children enrolled in single center therapeutic hypothermia clinical trials. (2021) (0)
- Abstract 141: Early Cytokine Profile in Selectively Vulnerable Brain Regions, Heart and Serum After Asphyxial Cardiac Arrest vs. Ventricular Fibrillation Cardiac Arrest in Rats (2020) (0)
- SUBSPECIALTY PLATFORM SESSION (1987) (0)
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- 27: BENEFITS OF LEVETIRACETAM AFTER CONTROLLED CORTICAL IMPACT IN RATS (2014) (0)
- P0493 / #1843: MUSIC THERAPY UTILIZATION IN PEDIATRIC CRITICAL CARE: A SINGLE SITE RETROSPECTIVE STUDY (2021) (0)
- Abstract 215: Hyperoxic versus Normoxic Resuscitation in Pediatric Asphyxial Cardiac Arrest: Effects on Hemodynamics, Mortality and Functional Outcome. (2010) (0)
- Brain-derived neurotrophic factor (BDNF) epigenomic modifications and brain-related phenotypes in humans: A systematic review (2022) (0)
- F Imaging Assessment of Labeled Macrophage Accumulation in a Mouse Brain Following Experimental Traumatic Brain Injury (2009) (0)
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- 576: OUTCOME IS ASSOCIATED WITH TYPE OF NEUROLOGIC DISEASE DURING SPECIALIZED TRANSPORT OF CHILDREN (2014) (0)
- 199: EXPRESSION OF MULTIDRUG RESISTANCE TRANSPORTERS IN HUMAN TRAUMATIC BRAIN INJURY (2012) (0)
- Abstract 11617: Personalizing Outcomes After Child Cardiac Arrest (POCCA): A Preliminary Biomarker Report (2021) (0)
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- Abstract 327: Asphyxial Cardiac Arrest Induces Dynamic Changes in Dopamine Neurotransmission and Linked Behavioral Deficits (2020) (0)
- P65: Nitrite after cardiac arrest has antioxidant effects reducing reperfusion cerebral hyperemia and subsequent caspase activation (2013) (0)
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- Pediatric Critical Care Medicine in the COVID-19 Pandemic (2020) (0)
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- Effect of Moderate Hyperthermia on Inflammation Following Experimental Traumatic Brain Injury in Mice (2012) (0)
- 1571: ROLE OF IL-17 AFTER TRAUMATIC BRAIN INJURY IN ADULT MICE (2018) (0)
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- 16: FGF21 THERAPY ATTENUATES ISCHEMIA-MEDIATED DOWNREGULATION OF NEUROPROTECTIVE RBM3 IN NEWBORN MICE (2022) (0)
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- 717: Adjunctive Decompressive Craniectomy Decreases Mortality in Pediatric Traumatic Brain Injury (2020) (0)
- Annual Safar Symposium (3rd) Held at University of Pittsburgh School of Medicine on 23 June 2005 (2005) (0)
- Abstract 18275: Exploratory Study of Emergency Cardiopulmonary Bypass for Resuscitation from Ventricular Fibrillation Cardiac Arrest in Rats (2010) (0)
- Traumatic Brain and Spinal Cord Injury: Metabolic and therapeutic differences in pediatric and adult TBI: implications for clinical care and therapeutic hypothermia (2012) (0)
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- 817: SERUM BIOMARKERS, QUALITY OF LIFE, AND FAMILY FUNCTIONING FOLLOWING PEDIATRIC NEUROCRITICAL ILLNESS (2019) (0)
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- EFFECT OF HEMORRHAGIC SHOCK ON NEURONAL DEATH AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY IN MICE.: 65 (2006) (0)
- Inducible NOS and Other Novel Mediators of Inflammation in Brain Trauma (1999) (0)
- Bedside pulmonary artery catheterization (2011) (0)
- 743: ACUTE INFLAMMATORY RESPONSE TO TRAUMATIC BRAIN INJURY IS AFFECTED BY MODULATORS OF GUT MICROBIOTA (2016) (0)
- 97 Gunshot wounds to the head: the epidemiology of severe paediatric firearm-related traumatic brain injuries (2017) (0)
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- 189: THE EFFECTS OF MINOCYCLINE IN A COMBINED MODEL OF TRAUMATIC BRAIN INJURY PLUS HEMORRHAGIC SHOCK IN M (2013) (0)
- P35: Nitrite as a novel resuscitation adjunct after ventricular fibrillation cardiac arrest in rats: A preliminary report (2013) (0)
- Abstract 16029: Increased Brain Injury After Asphyxial Cardiac Arrest vs. Ventricular Fibrillation is Associated With Greater Brain Antioxidant Depletion (2015) (0)
- Future Research Questions (2014) (0)
- Abstracts from the Literature (1996) (0)
- Ischemic Mechanisms in Traumatic Brain Injury (2003) (0)
- Reply to: Delta-opioid receptor ligands in shock treatment (2009) (0)
- Number DAMD 1797-1-7009 TITLE : Emergency Interventions After Severe Traumatic Brain Injury in Rats : Effect on Neuropatholgy and Functional Outcome (1999) (0)
- 15: CEREBROSPINAL FLUID LEVELS OF MITOCHONDRIAL DNA (DAMPS) IN PEDIATRIC TRAUMATIC BRAIN INJURY (2013) (0)
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- 375: OBJECTIVE QUANTIFICATION OF INTRACRANIAL HYPERTENSION - A NOVEL APPROACH (2012) (0)
- Poly-ADP-ribosylation is a prevalent post-translational modification of mitochondrial proteins in the brain (2005) (0)
- 10: HMGB1 TRANSLOCATION AND MICROGLIAL ACTIVATION AFTER PEDIATRIC TBI ATTENUATED BY MINOCYCLINE (2013) (0)
- 1301: An Exploratory Study of Cell Death Gene Changes After TBI in Novel RBM5 KO Mice (2020) (0)
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- 676: MONITORING AND THERAPEUTIC PRACTICE PATTERNS IN PEDIATRIC NEUROCRITICAL CARE (2020) (0)
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- 853: CEREBRAL AND EXTRACEREBRAL MANIFESTATIONS IN PEDIATRIC DROWNING (2012) (0)
- 2: Sur1 Pathway Genetic Variability May Impact MMP9 Secretion, Ca2+ Signaling, ICP, and Outcome in TBI (2020) (0)
- AGE-RELATED INCREASE IN PROTEIN KINASE B (AKT) AFTER PEDIATRIC TRAUMATIC BRAIN INJURY: 26 (2002) (0)
- Chapter 1: Introduction. Guidelines for the acute medical management of severe traumatic brain injury in infants children and adolescents (2003) (0)
- 1811: PREDICTORS OF DETERIORATION AND NEUROCRITICAL CARE USE IN PEDIATRIC MODERATE TRAUMATIC BRAIN INJURY (2019) (0)
- 6: MARKED COGNITIVE IMPAIRMENT IN GLOBAL, INDUCIBLE HMGB1 KO MICE DESPITE TISSUE SPARING AFTER TBI (2019) (0)
- Increased Adenosine Concentrations in Cerebral Spinal Fluid After Severe Traumatic Brain Injury in Children Paper #731 (1996) (0)
- Operation Brain Trauma Therapy Extended Studies (2015) (0)
- Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis (2023) (0)
- 823: INTRACRANIAL PRESSURE THRESHOLDS ASSOCIATED WITH MORTALITY IN PEDIATRIC NEUROCRITICAL CARE PATIENTS (2018) (0)
- Abstract P37: Blood Brain Barrier Integrity in Emergency Preservation and Resuscitation Rat Model (2008) (0)
- Pedigree Comics II (1995) (0)
- Therapeutic Hypothermia and Targeted Temperature Management With or Without the "Cold Stress" Response. (2017) (0)
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- 1: CSF Sur1 Is Associated With ICP and Outcome After Pediatric TBI: An Exploratory Study in Cool Kids (2020) (0)
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- 549: ANALYSIS OF NEUROPROTECTIVE COLD SHOCK PROTEINS IN A MULTICENTER STUDY OF PEDIATRIC CARDIAC ARREST (2022) (0)
- Abstracts From the Literature (1998) (0)
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- APOLIPOPROTEIN E AS PREDICTORS OF ACUTE BRAIN DYSFUNCTION AND SURVIVAL IN CRITICAL CARE PATIENTS (2014) (0)
- Abstracts from the Literature (1997) (0)
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- 9th Annual Safar Symposium (2012) (0)
- 551: SINGLE-CELL ATLAS REVEALS HETEROGENEOUS CELL COMMUNICATION IN MURINE TBI (2022) (0)
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- 38: MACHINE LEARNING PREDICTING MORTALITY AND MORBIDITY IN CHILDREN WITH NEUROLOGIC INJURY IN THE PICU (2020) (0)
- 652: UPLC-MS/MS METHOD FOR ASSESSING PHENYTOIN AND LEVETIRACETAM CONCENTRATIONS IN PEDIATRIC CA PATIENTS (2014) (0)
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- 775: SERUM BIOMARKER-BASED MODELS TO PREDICT INTRACRANIAL PRESSURE IN PEDIATRIC TRAUMATIC BRAIN INJURY (2016) (0)
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- 970: PHYSIOLOGY-BASED VENTILATOR COMPUTER DECISION SUPPORT OUTPERFORMS CLINICIANS IN AN IN SILICO TRIAL (2022) (0)
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- 779: ASCORBATE DEFICIENCY CONFERS RESISTANCE TO NEURODEGENERATION IN PEDIATRIC CARDIAC ARREST (2019) (0)
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- Abstract 18855: Hemoadsorption Removes Systemic Cytokines After Experimental Cardiac Arrest in Rats: A Dose-finding Study (2017) (0)
- 6 (2019) (0)
- Considerations for Chronic Recovery after Traumatic Brain Injury (2015) (0)
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- 1536: ABUSIVE HEAD TRAUMA AND MORTALITY: AN ANALYSIS FROM AN INTERNATIONAL COMPARATIVE EFFECTIVENESS STUDY (2016) (0)
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- Abstract 16280: Early Regional Neuroinflammatory Profile After Asphyxial Cardiac Arrest Vs. Ventricular Fibrillation Cardiac Arrest Model in Rats (2014) (0)
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- 2010 Presidential Citation Recipients (2005) (0)
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- 198: DELAYED HYPERTHERMIA EXACERBATES EXPERIMENTAL TRAUMATIC BRAIN INJURY (2012) (0)
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- 1382: DIVERGENT EFFECTS OF THERAPEUTIC HYPOTHERMIA ON COLD STRESS HORMONES AFTER PEDIATRIC CARDIAC ARREST (2021) (0)
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- 448: DEFINING THE ONSET OF INTRACRANIAL HYPERTENSION AFTER SEVERE TRAUMATIC BRAIN INJURY IN CHILDREN (2013) (0)
- 1000: NEURORADIOLOGIC AND HISTOPATHOLOGIC CORRELATES OF BRAIN INJURY IN A MURINE MODEL OF SEPSIS (2015) (0)
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- The Clinical Practice of Critical Care Neurology (Second Edition) (2004) (0)
- CEREBROSPINAL FLUID NITRITE/NITRATE AND CEREBRAL BLOOD FLOW AFTER HUMAN HEAD INJURY. (1995) (0)
- trial (Approaches and Decisions for Acute Pediatric TBI (ADAPT)) in the setting of severe paediatric TBI, funded by the US National Institutes of Health. (2013) (0)
- An exploratory assessment of the management of pediatric traumatic brain injury in three centers in Africa (2022) (0)
- Abstracts From the Literature (1997) (0)
- 464: NUTRITION TITRATED TO ENERGY EXPENDITURE IN CHILDREN WITH TRAUMATIC BRAIN INJURY-A FEASIBILITY STUDY (2013) (0)
- 1535: CHILD SURVIVAL FOLLOWING TRAUMATIC VERSUS NONTRAUMATIC OUT-OF-HOSPITAL CARDIAC ARREST (2019) (0)
- Publication of Cochrane Reviews in Critical Care Medicine and Pediatric Critical Care Medicine: guiding practice or duplicating the literature? (2002) (0)
- 1811 (1963) (0)
- Pediatric Critical Care Medicine: Accomplishments and Important New Initiatives. (2016) (0)
- Some historic firsts for Pediatric Critical Care Medicine. (2001) (0)
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What Schools Are Affiliated With Patrick M. Kochanek?
Patrick M. Kochanek is affiliated with the following schools:
