Patrick Mehlen
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French biologist
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Biology
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Cell Biology
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Molecular Biology
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Biology
Patrick Mehlen's Degrees
- PhD Molecular and Cellular Biology Claude Bernard University Lyon 1
Why Is Patrick Mehlen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Patrick Mehlen , is a French biologist and research director at the Centre national de recherche scientifique at the Centre Léon-Bérard, a cancer research centre in Lyon. Education Patrick Mehlen, a former student at the École normale supérieure de Lyon, defended his Ph.D. thesis at the Claude-Bernard University in 1995. From 1997 to 1998 he spent two sabbatical years at the Burnham Institute for Medical Research, program on "Aging and Cell Death" - Pr. D.E. Bredesen. Back in France, he became head of the "Apoptosis and Differentiation" group in the laboratory - CNRS UMR5534, CGMC until 2004. Then he became director of the "Apoptosis, Cancer and Development" research unit - CNRS FRE2870 then UMR5238 at the Léon Bérard Centre until 2011. He joined the Lyon Cancer Research Centre, where he became the director in 2019. He is also Director of Translational Research and Innovation at the Léon Bérard Centre since 2013, Director of the DEVweCAN Laboratory of Excellence since 2011 and Director of the Rabelais Institute for Interdisciplinary Cancer Research since 2018.
Patrick Mehlen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011) (2295)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Metastasis: a question of life or death (2006) (1680)
- Small Stress Proteins as Novel Regulators of Apoptosis (1996) (650)
- Human hsp27, Drosophila hsp27 and human alphaB‐crystallin expression‐mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha‐induced cell death. (1996) (580)
- Cell death in the nervous system (2006) (509)
- The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis (1998) (426)
- Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts. (1995) (364)
- Netrin‐1 acts as a survival factor via its receptors UNC5H and DCC (2001) (344)
- Inhibition of Neuroepithelial Patched-Induced Apoptosis by Sonic Hedgehog (2003) (324)
- Notch Signaling in the Tumor Microenvironment. (2018) (323)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Netrin-1 controls colorectal tumorigenesis by regulating apoptosis (2004) (294)
- Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression (1996) (276)
- Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation (2002) (259)
- HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs. (1997) (256)
- RGM and its receptor neogenin regulate neuronal survival (2004) (256)
- The RET proto‐oncogene induces apoptosis: a novel mechanism for Hirschsprung disease (2000) (245)
- Novel roles for Slits and netrins: axon guidance cues as anticancer targets? (2011) (235)
- Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFalpha in NIH-3T3-ras cells. (1997) (232)
- hsp27 as a Switch between Differentiation and Apoptosis in Murine Embryonic Stem Cells* (1997) (229)
- Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor (2000) (214)
- The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation (2001) (211)
- Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer (2008) (205)
- Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones. (1998) (196)
- TRAF Family Proteins Interact with the Common Neurotrophin Receptor and Modulate Apoptosis Induction* (1999) (190)
- The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment (2003) (188)
- The Patched dependence receptor triggers apoptosis through a DRAL–caspase-9 complex (2009) (150)
- The dependence receptor UNC5H2 mediates apoptosis through DAP‐kinase (2005) (150)
- Dependence receptors: a new paradigm in cell signaling and cancer therapy (2010) (147)
- Floor plate-derived netrin-1 is dispensable for commissural axon guidance (2017) (141)
- Role of the dependence receptor DCC in colorectal cancer pathogenesis. (2004) (132)
- Analysis of the resistance to heat and hydrogen peroxide stresses in COS cells transiently expressing wild type or deletion mutants of the Drosophila 27-kDa heat-shock protein. (1993) (130)
- Interference with netrin-1 and tumor cell death in non-small cell lung cancer. (2009) (129)
- Inhibition of endothelial cell apoptosis by netrin-1 during angiogenesis. (2009) (128)
- Netrin-1 acts as a survival factor for aggressive neuroblastoma (2009) (122)
- The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase. (2010) (121)
- The serum-induced phosphorylation of mammalian hsp27 correlates with changes in its intracellular localization and levels of oligomerization. (1994) (120)
- Tumor necrosis factor‐α induces changes in the phosphorylation, cellular localization, and oligomerization of human hsp27, a stress protein that confers cellular resistance to this cytokine (1995) (118)
- Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies. (2007) (118)
- Anaplastic Lymphoma Kinase Is a Dependence Receptor Whose Proapoptotic Functions Are Activated by Caspase Cleavage (2006) (115)
- The dependence receptor hypothesis (2004) (114)
- DCC constrains tumour progression via its dependence receptor activity (2011) (106)
- Netrin-1: when a neuronal guidance cue turns out to be a regulator of tumorigenesis (2005) (106)
- The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm (2007) (103)
- Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers. (2013) (102)
- Apoptosis and dependence receptors: a molecular basis for cellular addiction. (2004) (102)
- Intracellular reactive oxygen species as apparent modulators of heat-shock protein 27 (hsp27) structural organization and phosphorylation in basal and tumour necrosis factor alpha-treated T47D human carcinoma cells. (1995) (101)
- Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27. (1996) (99)
- Neurotrophins and cell death. (2012) (99)
- EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis. (2009) (99)
- Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B (2008) (99)
- Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production (2009) (97)
- Proapoptotic Function of the MET Tyrosine Kinase Receptor through Caspase Cleavage (2004) (95)
- Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression (2009) (95)
- Receptors that mediate cellular dependence (2005) (92)
- Netrin-1 role in angiogenesis: To be or not to be a pro-angiogenic factor? (2010) (80)
- Netrin-1 is a survival factor during commissural neuron navigation (2008) (78)
- Netrin‐1 Over Expression Protects Kidney From Ischemia Reperfusion Injury By Suppressing Apoptosis (2009) (78)
- DCC association with lipid rafts is required for netrin-1-mediated axon guidance (2005) (78)
- The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival (2003) (76)
- GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway (2003) (76)
- Small stress protein Hsp27 accumulation during dopamine-mediated differentiation of rat olfactory neurons counteracts apoptosis (1999) (75)
- Netrin-1 and its dependence receptors as original targets for cancer therapy (2010) (74)
- Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo (2012) (72)
- Dependence receptors: between life and death (2004) (72)
- NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors. (2008) (72)
- Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers. (2016) (71)
- Expression of netrin-1 and netrin-1 receptor, DCC, in the rat olfactory nerve pathway during development and axonal regeneration (2002) (67)
- Selective vulnerability in Alzheimer's disease: Amyloid precursor protein and p75NTR interaction (2009) (66)
- Amyloid Precursor Protein Regulates Netrin-1-mediated Commissural Axon Outgrowth* (2012) (66)
- Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes (2016) (63)
- Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis. (2010) (62)
- Dependence Receptors: From Basic Research to Drug Development (2011) (60)
- Dependence receptor TrkC is a putative colon cancer tumor suppressor (2013) (59)
- Interfering with multimerization of netrin-1 receptors triggers tumor cell death (2009) (57)
- Transient accumulation, phosphorylation and changes in the oligomerization of Hsp27 during retinoic acid-induced differentiation of HL-60 cells: possible role in the control of cellular growth and differentiation. (1996) (54)
- Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9 (2012) (54)
- Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity (2013) (53)
- Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers (2005) (53)
- Regulation of the 28 kDa heat shock protein by retinoic acid during differentiation of human leukemic HL‐60 cells (1994) (50)
- The Neogenin Intracellular Domain Regulates Gene Transcription via Nuclear Translocation (2008) (50)
- Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell Proliferation (2012) (50)
- Cancer-associated fibroblasts produce Netrin-1 to control cancer cell plasticity. (2019) (50)
- The dependence receptor DCC requires lipid raft localization for cell death signaling. (2006) (49)
- p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis (2017) (47)
- Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression. (2013) (44)
- Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression (2017) (41)
- Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance (2019) (41)
- Dependence Receptors and Cancer: Addiction to Trophic Ligands. (2015) (41)
- Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death (2013) (39)
- The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor. (2018) (38)
- Epidermal growth factor triggers an original, caspase-independent pituitary cell death with heterogeneous phenotype. (2004) (37)
- Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance (2015) (36)
- Patched-1 Proapoptotic Activity Is Downregulated by Modification of K1413 by the E3 Ubiquitin-Protein Ligase Itchy Homolog (2014) (36)
- Netrin-4 Acts as a Pro-angiogenic Factor during Zebrafish Development* (2011) (35)
- Non-canonical NOTCH3 signalling limits tumour angiogenesis (2017) (35)
- Netrin-1, a missing link between chronic inflammation and tumor progression (2010) (34)
- Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity (2013) (34)
- Morphogens and cell survival during development. (2005) (33)
- Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer. (2011) (33)
- Dependence receptors and colorectal cancer (2014) (31)
- Netrin-1 Expression Is an Independent Prognostic Factor for Poor Patient Survival in Brain Metastases (2014) (29)
- Regulation by miR181 family of the dependence receptor CDON tumor suppressive activity in neuroblastoma. (2014) (29)
- Analysis of the Dominant Effects Mediated by Wild Type or R120G Mutant of αB-crystallin (HspB5) towards Hsp27 (HspB1) (2013) (29)
- Dependence receptors – the dark side awakens (2018) (29)
- Dependence receptors: when apoptosis controls tumor progression. (2007) (28)
- DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment (2017) (27)
- Lipid raft localization and palmitoylation: identification of two requirements for cell death induction by the tumor suppressors UNC5H. (2008) (26)
- Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1 (2021) (26)
- The dependence receptor TrkC triggers mitochondria-dependent apoptosis upon Cobra-1 recruitment. (2013) (25)
- Dependence Receptors: The Trophic Theory Revisited (2010) (25)
- Unraveling the Role of Huntingtin in Breast Cancer Metastasis. (2015) (25)
- Inhibitory Role of Endophilin 3 in Receptor-mediated Endocytosis* (2004) (24)
- Targeting netrin‐1/DCC interaction in diffuse large B‐cell and mantle cell lymphomas (2016) (24)
- Clonal expansion of HTLV-1 positive CD8+ cells relies on cIAP-2 but not on c-FLIP expression. (2010) (23)
- Inhibition of DNA methylation promotes breast tumor sensitivity to netrin‐1 interference (2016) (21)
- Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features (2020) (21)
- The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death (2018) (21)
- Sonic Hedgehog promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development. (2014) (20)
- Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2015) (19)
- Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling (2020) (19)
- Netrin-1 overexpression in kidney proximal tubular epithelium ameliorates cisplatin nephrotoxicity (2011) (18)
- BDNF and Netrin-1 repression by C/EBPβ in the gut triggers Parkinson’s disease pathologies, associated with constipation and motor dysfunctions (2020) (18)
- Ultrasound molecular imaging as a non-invasive companion diagnostic for netrin-1 interference therapy in breast cancer (2018) (17)
- RET Modulates Cell Adhesion via Its Cleavage by Caspase in Sympathetic Neurons* (2011) (17)
- Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1 (2018) (17)
- Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease. (2016) (16)
- ϒ-secretase and LARG mediate distinct RGMa activities to control appropriate layer targeting within the optic tectum (2015) (15)
- Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis (2020) (13)
- A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis (2021) (13)
- Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus (2016) (13)
- Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response (2016) (13)
- The dependence receptor notion: another way to see death (2005) (12)
- Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth (2018) (12)
- Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration. (2020) (11)
- Netrin-1 and its receptor DCC are causally implicated in melanoma progression. (2019) (11)
- Serine protease inhibitor Spi2 mediated apoptosis of olfactory neurons (2002) (11)
- Dependence receptors: new targets for cancer therapy (2021) (10)
- Immune checkpoint inhibitor treatment of a first cancer is associated with a decreased incidence of second primary cancer (2021) (10)
- Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4 (2017) (9)
- Biochemical and immunofluorescence analysis of the constitutively expressed HSP27 stress protein in monkey CV-1 cells (1996) (9)
- Molecular characterization of Netrin-1 and APP receptor binding: New leads to block the progression of senile plaques in Alzheimer's disease. (2017) (9)
- Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4. (2017) (9)
- Hela cells proteasome interacts with leucine-rich polypeptides and contains a phosphorylated subunit. (1993) (9)
- [Netrin-1 and axonal guidance: signaling and asymmetrical translation]. (2007) (8)
- Meeting Report: Cellular Dependence--Old Concept, New Mechanisms (2003) (8)
- RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas (2021) (8)
- Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus (2017) (8)
- Caprine arthritis-encephalitis virus induces apoptosis in infected cells in vitro through the intrinsic pathway. (2008) (8)
- Targeting netrin‐3 in small cell lung cancer and neuroblastoma (2021) (6)
- [Dependence receptors DCC and UNC5H: the role of apoptosis in the control of tumorigenesis]. (2005) (6)
- Small ruminant lentivirus Tat protein induces apoptosis in caprine cells in vitro by the intrinsic pathway. (2009) (6)
- Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death. (2002) (6)
- Ephrin-B 3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA 4 (2017) (6)
- Hepatic inflammation elicits production of proinflammatory netrin‐1 through exclusive activation of translation (2022) (5)
- A first in human, phase I trial of NP137, a first-in-class antibody targeting netrin-1, in patients with advanced refractory solid tumors (2019) (5)
- [Dependence receptors: links between apoptosis, nervous system development and control of tumorigenesis]. (2000) (5)
- Bevacizumab impairs hepatocyte proliferation after partial hepatectomy in a rabbit model. (2012) (5)
- [Dependence receptors: life or death choices]. (2013) (5)
- [Patched is a dependence receptor]. (2003) (4)
- Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity (2021) (4)
- apoptosis by a mechanism requiring receptor proteolysis (1998) (3)
- Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes. (2018) (3)
- The dependence receptor TrkC regulates the number of sensory neurons during DRG development. (2018) (3)
- Fifteen important questions for oncology to be addressed from 2015 (2015) (2)
- Detection of tumoral netrin-1 protein levels using ultrasound microbubble contrast agents: In vitro validation (2016) (2)
- Murine embryonic stem cells as a model for stress proteins and apoptosis during differentiation. (2002) (2)
- Abstract 2921: Preclinical characteristics of NP137, a first-in-class monoclonal antibody directed against netrin-1 and inducing dependence receptors-mediated cell death (2015) (2)
- Neurobiology: A new way to network (2003) (2)
- [Netrin-1 and its dependence receptors: role in colorectal cancers]. (2005) (1)
- Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network (2022) (1)
- Dynamics of MBD 2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2015) (1)
- La notion de dependance receptor, Dr. Jeckyll and M. Hide. (2001) (1)
- Novel prionic and anti-prionic mechanisms in Alzheimer's disease (2011) (1)
- Metastatic infiltration of nervous tissue and periosteal nerve sprouting in multiple 1 myeloma induced bone pain 2 Abbreviated title : Myeloma-induced bone pain (2023) (0)
- Expression of c-kit/SCF tyrosine kinase signaling pathway and apoptotic genes in ionomycin/PMA treated Jurkat cells (2008) (0)
- DCC/netrin-1 regulates cell death in oligodendrocytes after brain injury (2022) (0)
- Heat Shock Protein 27 Enhances the Tumorigenicity of Immunogenic Rat Colon Carcinoma Cell Clones1 (2006) (0)
- 372 Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting the dependence receptor TrkC-induced apoptosis (2010) (0)
- 736 The Deleted in Colorectal Cancer (DCC) Dependence Receptor Constrains Tumor Progression in Colorectal Cancer Via Induction of Apoptosis (2012) (0)
- P0412 : Netrin-1 protects against hepatocytic cell death upon UPR through sustained translation in an UNC5A/C-dependent fashion (2015) (0)
- 817TiP GYNET study - Safety and efficacy of anti-netrin 1 (NP137) in combination with chemotherapy and/or pembrolizumab in patients (pts) with pretreated locally advanced/metastatic endometrial carcinoma or cervix carcinoma: An adaptive multi-arms randomized phase I/II trial (2021) (0)
- Hepatic inflammation upregulates netrin-1 in mice and in vitro through translational activation and transcript topology alteration in a LA-related protein-1 (LARP1)-dependent manner (2020) (0)
- Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma (2022) (0)
- The ret proto‐oncogene induces apoptosis: Proapoptotic activity and hirschsprung disease (1999) (0)
- Abstract 3036: The dependence receptor TrkC is a putative colon cancer tumor suppressor. (2013) (0)
- 368 NP137, the first humanized monoclonal antibody directed against netrin-1, exhibits antitumor activity by inducing dependence receptors-mediated cell death (2014) (0)
- Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer (2023) (0)
- Development of Targeted Microbubbles for Ultrasound Molecular Imaging of Breast Cancer (2015) (0)
- Metastatic infiltration of nervous tissue and periosteal nerve sprouting in multiple myeloma induced bone pain (2023) (0)
- Edinburgh Research Explorer Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells during (2018) (0)
- [Hepatitis C, EGFR, cirrhosis and netrin-1: potential implications for HCC onset]. (2016) (0)
- Bone innervation and vascularization regulated by osteoclasts contribute to refractive pain-related behavior in the collagen antibody-induced arthritis model (2021) (0)
- Netrin-1 is a Novel Therapeutic Target for Metastatic Pancreatic Cancer (2020) (0)
- Analysis of the role of RET as a dependence receptor during development of the enteric nervous system in the chick embryo (2005) (0)
- P0686 : Reciprocal antagonism between the uncoordinated phenotype-5A (UNC5A) dependence receptor and the hepatitis C virus (2015) (0)
- [The netrin-1 cue regulates somatic cell reprogramming to pluripotency]. (2016) (0)
- Abstract 5291: Netrin-1 expression and targeting in multiple myeloma (2019) (0)
- The dependence receptor DCC defines a new mechanism for caspase activation (1999) (0)
- Ultrasound molecular imaging of the secreted tumor marker Netrin-1 in multiple breast cancer models (2017) (0)
- Altered heat‐shock response in mouse NIH 3T3 cells expressing either v‐FOS or Ha‐RAS 1 oncogen (1992) (0)
- Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling (2020) (0)
- HTLV-1 Triggers HIAP-1 and cFLIP Expression in CD8+ T-Cells While Impairing DNA Repair in CD4+ T-Cells. (2008) (0)
- The dependence receptor notion: when apoptosis regulates tumor progression and metastasis (2008) (0)
- MCB 01515-05 ( Version 3 ) : revised-3-FINAL 1 ALK IS A DEPENDENCE RECEPTOR WHOSE PROAPOPTOTIC FUNCTIONS ARE ACTIVATED BY CASPASE CLEAVAGE (2006) (0)
- O3-05-06 EPIGENETIC REGULATION OF TAU GENE EXPRESSION (2019) (0)
- [Detection and quantification of apoptosis in tissues: a challenge]. (2009) (0)
- Results rB-dependent Transactivation of a Reporter Gene by TNFa and Hydrogen Peroxide Is Inhibited in T 47 D Cells that Overexpress GSHPx (1996) (0)
- 277 POSTER Expression of the genes involved in apoptosis, proliferation and endoplasmic reticulum stress in ionomycin/PMA treated Jurkat cells (2008) (0)
- [The deadly rafts: when lipid rafts regulate dependence receptors]. (2006) (0)
- The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death (2018) (0)
- Abstract B020: Retinoic acid produced by hepatic stellate cells facilitates Netrin-1 mediated pancreatic cancer metastasis (2022) (0)
- Targeting netrin-1 / DCC interaction in Diffuse Large-B and Mantle Cell Lymphoma (2015) (0)
- Programmed necrosis controls germ cell homeostasis during Drosophila spermatogenesis (2016) (0)
- Abstract 28: The Netrin-1 receptor UNC5C is a tumor suppressor in colorectal malignancies (2012) (0)
- 8 – Programmed Cell Death and Its Role in Neurological Disease (2007) (0)
- Implications of Unc5A depletion for hepatocyte survival in chronic liver diseases upon induction of the unfolded protein response (2017) (0)
- Netrin-4 regulates stiffness and metastasis (2021) (0)
- Molecular correlates of neuronal apoptosis in olfactory epithelium of adult mouse (1999) (0)
- The rapid phosphorylation of the small stress protein by TNF is probably linked to the cellular resistance to this monokine (1992) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- 126 INTERPLAY BETWEEN NETRIN-1 AND HCV REPLICATION IN VITRO AND IN PATIENTS WITH CHRONIC HEPATITIS C (2012) (0)
- Immunohistochemical Expression of Netrin-1 in Canine Lymphomas (2018) (0)
- Netrin-1: a promising therapeutic target in metastatic breast cancer. Expression analysis in localized and metastatic breast tumors and preclinical validation. (2009) (0)
- Dependence Receptors and Apoptosis (2008) (0)
- The dependence receptor notion: from a cell biology paradigm to alternative anti-cancer therapies (2013) (0)
- From netrin‐1‐targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors (2023) (0)
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