Patrick O. Brown | Academic Influence

Patrick O. Brown's AcademicInfluence.com Rankings

Patrick O. Brown

Philosophy

#3090

World Rank

#5074

Historical Rank

#1014

USA Rank

Logic

#948

World Rank

#1544

Historical Rank

#320

USA Rank

philosophy Degrees

Patrick O. Brown

Biology

#3562

World Rank

#5429

Historical Rank

#1435

USA Rank

Biotechnology

#21

World Rank

#21

Historical Rank

#10

USA Rank

Molecular Biology

#252

World Rank

#256

Historical Rank

#106

USA Rank

Genetics

#276

World Rank

#327

Historical Rank

#131

USA Rank

biology Degrees

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Philosophy
Biology

Patrick O. Brown's Degrees

Bachelors Biochemistry University of Chicago
Doctorate Medicine University of Chicago
PhD Biochemistry University of Chicago

Why Is Patrick O. Brown Influential?

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According to Wikipedia, Patrick O'Reilly Brown is an American scientist and businessman who is the founder of Impossible Foods Inc. and professor emeritus in the department of biochemistry at Stanford University. Brown is co-founder of the Public Library of Science, inventor of the DNA microarray, and a former investigator at Howard Hughes Medical Institute.

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Patrick O. Brown's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Molecular portraits of human breast tumours (2000) (14829)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications (2001) (10949)
Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray (1995) (9916)
Repeated observation of breast tumor subtypes in independent gene expression data sets (2003) (5412)
Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. (1998) (5332)
Genomic expression programs in the response of yeast cells to environmental changes. (2000) (4895)
Exploring the metabolic and genetic control of gene expression on a genomic scale. (1997) (4781)
Missing value estimation methods for DNA microarrays (2001) (3484)
Development of the Human Infant Intestinal Microbiota (2007) (2685)
Exploring the new world of the genome with DNA microarrays (1999) (2562)
Systematic variation in gene expression patterns in human cancer cell lines (2000) (2228)
Use of a cDNA microarray to analyse gene expression patterns in human cancer (1996) (2148)
The transcriptional program in the response of human fibroblasts to serum. (1999) (2092)
Singular value decomposition for genome-wide expression data processing and modeling. (2000) (2023)
The transcriptional program of sporulation in budding yeast. (1998) (1984)
Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types (2012) (1970)
Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. (1996) (1671)
Identification of genes periodically expressed in the human cell cycle and their expression in tumors. (2002) (1529)
Genome-wide analysis of DNA copy-number changes using cDNA microarrays (1999) (1510)
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. (1999) (1478)
A gene expression database for the molecular pharmacology of cancer (2000) (1461)
Cell-Type Specific Features of Circular RNA Expression (2013) (1461)
Gene expression profiling identifies clinically relevant subtypes of prostate cancer. (2004) (1350)
Diversity of gene expression in adenocarcinoma of the lung (2001) (1320)
Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia (2001) (1215)
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors (2002) (1200)
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF (2001) (1191)
A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. (1996) (1190)
DNA arrays for analysis of gene expression. (1999) (1119)
Diversity, topographic differentiation, and positional memory in human fibroblasts (2002) (1065)
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. (2005) (989)
Integration of murine leukemia virus DNA depends on mitosis. (1993) (987)
Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds (2004) (967)
Gene expression patterns in human liver cancers. (2002) (871)
Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions (2001) (867)
Individuality and variation in gene expression patterns in human blood (2003) (822)
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. (2001) (821)
Precision and functional specificity in mRNA decay (2002) (767)
Yeast microarrays for genome wide parallel genetic and gene expression analysis. (1997) (753)
Endothelial cell diversity revealed by global expression profiling (2003) (729)
Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae (2003) (699)
Extensive Association of Functionally and Cytotopically Related mRNAs with Puf Family RNA-Binding Proteins in Yeast (2004) (689)
Autoantigen microarrays for multiplex characterization of autoantibody responses (2002) (671)
Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors (2003) (671)
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein–DNA association (2001) (654)
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers (2006) (628)
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. (2004) (626)
'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns (2000) (625)
Genome-wide analysis of DNA copy number variation in breast cancer using DNA microarrays (1999) (601)
Molecular characterisation of soft tissue tumours: a gene expression study (2002) (597)
Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System (2008) (591)
Circular RNA Is Expressed across the Eukaryotic Tree of Life (2014) (585)
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. (2001) (581)
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization. (1999) (573)
The Stanford Microarray Database (2001) (569)
Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae (2002) (567)
Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. (2005) (508)
Systematic changes in gene expression patterns following adaptive evolution in yeast. (1999) (508)
New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. (2000) (503)
Drug target validation and identification of secondary drug target effects using DNA microarrays (1998) (470)
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. (2003) (466)
SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data (2003) (466)
Gene expression patterns in human placenta. (2006) (451)
Stereotyped and specific gene expression programs in human innate immune responses to bacteria (2002) (447)
Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs (2006) (440)
Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA (2009) (437)
Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae. (2000) (423)
Correct integration of retroviral DNA in vitro (1987) (419)
A transcriptional response to Wnt protein in human embryonic carcinoma cells (2002) (415)
Genome-wide Analysis of Gene Expression Regulated by the Calcineurin/Crz1p Signaling Pathway in Saccharomyces cerevisiae * (2002) (414)
A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. (2006) (412)
Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray. (1999) (411)
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. (2000) (411)
Systemic and cell type-specific gene expression patterns in scleroderma skin (2003) (410)
Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth (2000) (380)
A nucleoprotein complex mediates the integration of retroviral DNA. (1989) (379)
The Stanford Microarray Database: data access and quality assessment tools (2003) (379)
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation (2002) (372)
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. (1989) (367)
Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus. (1992) (359)
Energy coupling in DNA gyrase and the mechanism of action of novobiocin. (1978) (346)
Nonparametric methods for identifying differentially expressed genes in microarray data (2002) (338)
Regulation of CSF1 Promoter by the SWI/SNF-like BAF Complex (2001) (334)
Gene expression patterns in ovarian carcinomas. (2003) (333)
Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms (2003) (325)
Variation in gene expression patterns in human gastric cancers. (2003) (316)
Genomewide view of gene silencing by small interfering RNAs (2003) (315)
Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase. (2000) (312)
Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis (2003) (303)
Cell-type specific gene expression profiles of leukocytes in human peripheral blood (2006) (301)
Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster. (2006) (301)
Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes. (1999) (301)
Diverse and specific gene expression responses to stresses in cultured human cells. (2004) (300)
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli (2004) (300)
Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast. (2000) (298)
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation (2006) (295)
Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. (2000) (290)
Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants (2000) (283)
Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. (1993) (282)
Transcriptome-Wide Mapping of Pseudouridines: Pseudouridine Synthases Modify Specific mRNAs in S. cerevisiae (2014) (279)
The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. (1999) (272)
A sign inversion mechanism for enzymatic supercoiling of DNA. (1979) (260)
Functional Analysis of the Genes of Yeast Chromosome V by Genetic Footprinting (1996) (250)
Imputing Missing Data for Gene Expression Arrays (2001) (249)
Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments (2014) (247)
The Preclinical Natural History of Serous Ovarian Cancer: Defining the Target for Early Detection (2009) (245)
Adaptation to famine: A family of stationary-phase genes revealed by microarray analysis (2002) (244)
DNA strand exchange and selective DNA annealing promoted by the human immunodeficiency virus type 1 nucleocapsid protein (1994) (243)
A DNA microarray survey of gene expression in normal human tissues (2005) (242)
Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes (2002) (241)
Modulation of Cellular and Viral Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus (2001) (229)
Shotgun DNA microarrays and stage‐specific gene expression in Plasmodium falciparum malaria (2000) (228)
DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli. (2000) (226)
Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays (2001) (222)
Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments (2006) (221)
The Stanford Microarray Database accommodates additional microarray platforms and data formats (2004) (220)
Supervised harvesting of expression trees (2001) (215)
Predicting a local recurrence after breast-conserving therapy by gene expression profiling (2006) (209)
Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent (1999) (207)
Global and Specific Translational Regulation in the Genomic Response of Saccharomyces cerevisiae to a Rapid Transfer from a Fermentable to a Nonfermentable Carbon Source (2001) (206)
Correction: Cell-Type Specific Features of Circular RNA Expression (2013) (206)
A specific gene expression program triggered by Gram-positive bacteria in the cytosol. (2004) (206)
Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance (2008) (205)
Transcriptional programs activated by exposure of human prostate cancer cells to androgen (2002) (203)
Determination of Stromal Signatures in Breast Carcinoma (2005) (201)
Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. (2003) (199)
Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway. (2000) (198)
Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays. (2000) (197)
Rapid quantitative profiling of complex microbial populations (2006) (192)
The Stanford Microarray Database: implementation of new analysis tools and open source release of software (2006) (190)
Supramolecular organization of immature and mature murine leukemia virus revealed by electron cryo-microscopy: implications for retroviral assembly mechanisms. (1998) (190)
Identification of the Copper Regulon in Saccharomyces cerevisiae by DNA Microarrays* (2000) (190)
Why PLoS Became a Publisher (2003) (188)
Characterization of three related glucose repressors and genes they regulate in Saccharomyces cerevisiae. (1998) (186)
Desferrioxamine-mediated Iron Uptake in Saccharomyces cerevisiae (2000) (182)
Mediator protein mutations that selectively abolish activated transcription. (1999) (178)
Genetic footprinting: a genomic strategy for determining a gene's function given its sequence. (1995) (172)
Human immunodeficiency virus integration in a cell-free system (1990) (170)
Human Immunodeficiency Virus Type 1 Vectors Efficiently Transduce Human Hematopoietic Stem Cells (1998) (169)
Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations (1993) (169)
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis (2002) (168)
Genomic views of the immune system*. (2000) (166)
In vivo regulation of human skeletal muscle gene expression by thyroid hormone. (2002) (165)
RERG Is a Novel ras-related, Estrogen-regulated and Growth-inhibitory Gene in Breast Cancer* (2001) (163)
Proteome-Wide Search Reveals Unexpected RNA-Binding Proteins in Saccharomyces cerevisiae (2010) (163)
Large-scale identification of secreted and membrane-associated gene products using DNA microarrays (1999) (162)
Three Cell Wall Mannoproteins Facilitate the Uptake of Iron in Saccharomyces cerevisiae * (2001) (160)
Integration of retroviral DNA. (1990) (160)
Variation in gene expression patterns in follicular lymphoma and the response to rituximab (2003) (158)
Bethesda Statement on Open Access Publishing (2003) (158)
Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex. (1998) (157)
miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway (2014) (157)
A second iron-regulatory system in yeast independent of Aft1p (2001) (156)
Detection and Characterizationof Cellular Immune Responses Using Peptide–MHC Microarrays (2003) (155)
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. (1994) (151)
Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. (2003) (150)
Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells (2010) (146)
Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression. (2001) (145)
Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases (2012) (142)
Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes (2011) (142)
Genomic mismatch scanning: a new approach to genetic linkage mapping (1993) (141)
Discovery and validation of breast cancer subtypes (2006) (140)
Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking. (1997) (137)
Dissecting eukaryotic translation and its control by ribosome density mapping (2005) (134)
Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. (2003) (133)
Role of thioredoxin reductase in the Yap1p‐dependent response to oxidative stress in Saccharomyces cerevisiae (2001) (132)
Sequence requirements for efficient translational frameshifting in the Escherichia coli dnaX gene and the role of an unstable interaction between tRNA(Lys) and an AAG lysine codon. (1992) (129)
Genomewide demarcation of RNA polymerase II transcription units revealed by physical fractionation of chromatin (2003) (126)
Catenation and knotting of duplex DNA by type 1 topoisomerases: a mechanistic parallel with type 2 topoisomerases. (1981) (126)
Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer. (2007) (125)
An Essential Interaction between Distinct Domains of HIV-1 Integrase Mediates Assembly of the Active Multimer (*) (1995) (124)
Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function (2010) (118)
The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. (2004) (117)
Genomics and human disease—variations on variation (1998) (114)
Two-dimensional crystallization of histidine-tagged, HIV-1 reverse transcriptase promoted by a novel nickel-chelating lipid. (1994) (112)
T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression (2003) (108)
A topoisomerase from Escherichia coli related to DNA gyrase. (1979) (107)
Gene expression in the normal adult human kidney assessed by complementary DNA microarray. (2003) (106)
Genome-wide analysis of mRNA lengths in Saccharomyces cerevisiae (2003) (105)
Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues (2007) (98)
Visualizing associations between genome sequences and gene expression data using genome-mean expression profiles (2001) (97)
Systematic Evaluation of Candidate Blood Markers for Detecting Ovarian Cancer (2008) (94)
The Stanford Tissue Microarray Database (2007) (94)
DNA Methylation Profiles of Ovarian Epithelial Carcinoma Tumors and Cell Lines (2010) (93)
Marked Differences in Human Melanoma Antigen-Specific T Cell Responsiveness after Vaccination Using a Functional Microarray (2005) (90)
Genome-Scale Identification of Membrane-Associated Human mRNAs (2006) (90)
Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer (2007) (90)
Probing Lymphocyte Biology by Genomic-Scale Gene Expression Analysis (1998) (87)
Apo D in Soft Tissue Tumors: A Novel Marker for Dermatofibrosarcoma Protuberans (2004) (86)
The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever (2007) (86)
Gene-expression patterns reveal underlying biological processes in Kawasaki disease (2007) (86)
Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro. (2007) (84)
Disruption of the terminal base pairs of retroviral DNA during integration. (1997) (83)
Transcriptional Program Induced by Wnt Protein in Human Fibroblasts Suggests Mechanisms for Cell Cooperativity in Defining Tissue Microenvironments (2007) (82)
Statistical methods for linkage analysis of complex traits from high-resolution maps of identity by descent. (1995) (80)
Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11 (2002) (79)
Identification of RNA recognition elements in the Saccharomyces cerevisiae transcriptome (2010) (77)
Effects of Mutations in Residues near the Active Site of Human Immunodeficiency Virus Type 1 Integrase on Specific Enzyme-Substrate Interactions (1998) (76)
Gene Shaving: a new class of clustering methods for expression arrays (2000) (73)
Differential gene expression in anatomical compartments of the human eye (2005) (69)
Comparative genome-scale analysis of gene expression profiles in T cell lymphoma cells during malignant progression using a complementary DNA microarray. (2001) (67)
Structure and activities of Escherichia coli DNA gyrase. (1979) (66)
Observing the living genome. (1999) (66)
Gene Expression Programs of Human Smooth Muscle Cells: Tissue-Specific Differentiation and Prognostic Significance in Breast Cancers (2007) (66)
Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. (2000) (65)
Substrate features important for recognition and catalysis by human immunodeficiency virus type 1 integrase identified by using novel DNA substrates (1994) (61)
Comparative Analysis of Viral Gene Expression Programs during Poxvirus Infection: A Transcriptional Map of the Vaccinia and Monkeypox Genomes (2008) (58)
Quantitative proteomic analysis reveals concurrent RNA–protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae (2013) (57)
Presynaptic homeostasis at CNS nerve terminals compensates for lack of a key Ca2+ entry pathway. (2004) (57)
Stunned Silence: Gene Expression Programs in Human Cells Infected with Monkeypox or Vaccinia Virus (2011) (57)
The Core Domain of HIV-1 Integrase Recognizes Key Features of Its DNA Substrates* (1997) (55)
Building A "GenBank" of the Published Literature (2001) (55)
Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets (2015) (55)
Haa1, a Protein Homologous to the Copper-regulated Transcription Factor Ace1, Is a Novel Transcriptional Activator* (2001) (52)
ESRRA-C11orf20 Is a Recurrent Gene Fusion in Serous Ovarian Carcinoma (2011) (50)
A gene-expression program reflecting the innate immune response of cultured intestinal epithelial cells to infection by Listeria monocytogenes (2002) (49)
Host sequences flanking the HIV provirus. (1990) (46)
Monoclonal antibodies against human immunodeficiency virus type 1 integrase: epitope mapping and differential effects on integrase activities in vitro (1996) (46)
Processing and modeling genome-wide expression data using singular value decomposition (2001) (45)
Differential gene-expression patterns in genital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome: evidence for early programming involving the androgen receptor (2003) (44)
Comprehensive Mutational Analysis of the Moloney Murine Leukemia Virus Envelope Protein (2001) (43)
Stereospecificity of Reactions Catalyzed by HIV-1 Integrase* (1999) (42)
Functional Characterization of the Human Immunodeficiency Virus Type 1 Genome by Genetic Footprinting (2000) (42)
Ovarian Cancer Early Detection Claims Are Biased (2008) (42)
Juxtaposition of two viral DNA ends in a bimolecular disintegration reaction mediated by multimers of human immunodeficiency virus type 1 or murine leukemia virus integrase (1994) (40)
High-resolution functional mapping of a cloned gene by genetic footprinting. (1997) (38)
3'-end processing and kinetics of 5'-end joining during retroviral integration in vivo (1997) (38)
Minimizing off-target effects by using diced siRNAs for RNA interference (2006) (36)
Cancer characterization and feature set extraction by discriminative margin clustering (2004) (35)
Characterization of recombinant murine leukemia virus integrase (1995) (34)
Di erent types of di use large b-cell lymphoma identi ed by gene expression pro ling (2000) (34)
Observing the living genome (1999) (33)
Genome-wide Analysis of Gene Expression Regulated by the Calcineurin / Crz 1 p Signaling Pathway in Saccharomyces cerevisiae * (2002) (33)
Examining the living genome in health and disease with DNA microarrays. (2000) (32)
The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of HAC1 RNA (2012) (29)
Genomic analysis of renal allograft dysfunction using cDNA microarrays. (2001) (27)
Rapid global phaseout of animal agriculture has the potential to stabilize greenhouse gas levels for 30 years and offset 68 percent of CO2 emissions this century (2022) (26)
Use of microgenomic technology for analysis of alterations in DNA copy number and gene expression in malignant melanoma. (1997) (24)
Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling (2015) (24)
Enrichment for loci identical-by-descent between pairs of mouse or human genomes by genomic mismatch scanning. (1998) (21)
Directed Chemical Evolution with an Outsized Genetic Code (2016) (20)
Widespread mRNA Association with Cytoskeletal Motor Proteins and Identification and Dynamics of Myosin-Associated mRNAs in S. cerevisiae (2012) (18)
Tumor classification using gene expression patterns from DNA microarrays (2000) (16)
NOVEL GENOME-SCALE CORRELATION BETWEEN DNA REPLICATION AND RNA TRANSCRIPTION DURING THE CELL CYCLE IN YEAST IS PREDICTED BY DATA-DRIVEN MODELS (2004) (15)
Virtual Northern Analysis of the Human Genome (2007) (15)
Development of the Human Infant Intestinal (2007) (14)
Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells (2016) (14)
A method for detecting and correcting feature misidentification on expression microarrays (2004) (13)
Genome scanning methods. (1994) (13)
implications Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical (2001) (12)
Discovery and validation of breast cancer subtypes (2007) (10)
Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays (2002) (10)
Neural Stem Cells and Gene Therapy : Prospects for Repairing the Injured Spinal Cord (2000) (9)
PLoS Medicine— A Medical Journal for the Internet Age (2004) (9)
Should the scientific literature be privately owned and controlled (2001) (7)
Corrigendum to “Functional genomic analysis of a commercial wine strain of Saccharomyces cerevisiae under different nitrogen conditions” [FEMS Yeast Res. 1 (2001) 111–125] (2003) (7)
MECHANISMS OF DNA TOPOISOMERASES (1980) (6)
IN VITRO REPLICATION OF YEAST 2-μm PLASMID DNA (1981) (6)
Coordinate Regulation of Yeast Ribosomal Protein Genes Is Associated with Targeted Recruitment of Esa 1 Histone Acetylase nucleosomes (2000) (5)
Functional and molecular profiling of heterogeneous tumor samples using a novel cellular microarray. (2004) (5)
Public-access group supports PubMed Central (2002) (5)
A cDNA microarray gene expression database for cancer drug discovery (1999) (5)
Representing DC-Coupled PV+Battery Hybrids in a Capacity Expansion Model (2021) (5)
Identification of clinically distinct types of diffuse large B-cell lymphoma based on gene expressio (2000) (5)
An interview with Patrick O Brown on the origins and future of open access (2013) (4)
Correction: Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance (2008) (4)
A novel cellular microarray identifies functional deficiencies in tumor-specific T cell responses. (2004) (4)
Correction: A DNA microarray survey of gene expression in normal human tissues (2005) (4)
Differential Gene Expression Profiles in CD34+ Myelodysplastic Syndrome Marrow Cells. (2005) (3)
Correction: Circular RNA Is Expressed across the Eukaryotic Tree of Life (2014) (3)
Genome-scale Identification of Secreted and Membrane-associated Tumor Markers (2005) (2)
Improved Discovery of Molecular Interactions in Genome-Scale Data with Adaptive Model-Based Normalization (2013) (2)
Rapid global phaseout of animal agriculture has the potential to stabilize greenhouse gas levels for 30 years and offset 68 percent of CO2 emissions (2021) (2)
Virtual Northern analysis of the human genome. (2007) (2)
Genome-wide maps of DNA-protein interactions using a yeast ORF and intergenic microarray (1999) (2)
Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions (2000) (2)
Functional clustering of genes using microarray gene expression data (1999) (2)
Erratum: Diversity of gene expression in adenocarcinoma of the lung (Proceedings of the National Academy of Sciences of the United States of America (2001) 98 (13784-13789)) (2002) (2)
ANALYSIS OF HOST VIRAL INTERACTIONS IN CMV INFECTION USING DNA MICROARRAYS. (1999) (1)
Title Gene expression patterns in pancreatic tumors , cells andtissues (2007) (1)
Short Communication Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome (2002) (1)
Gene expression profiling using a mouse full-length 20 K cDNA microarray (1999) (1)
Mapping single and multigenetic traits in S. cerevisiae by genomic mismatch scanning and DNA microarrays (1999) (1)
Public Library of Science Initiative - Open Letter (2000) (1)
Stem Cells Efficiently Transduce Human Hematopoietic Human Immunodeficiency Virus Type 1 Vectors (1998) (1)
Ovarian Cancer Early Detection Claims Are Biased. Authors' reply (2008) (0)
QS394. The Genomic Analysis of the Heterogeneity Hypoxia Responses in Renal Proximal Tubule Epithelial Cells After Knock-Down of HIF-1α and HIF-2α (2008) (0)
Recombinant Dicer-Generated siRNA Reduces Off-Target Effects Compared to Chemically Synthesized siRNAs (2009) (0)
Development of an MHC-peptide array for the detection and isolation of antigen-specific T-cells: applications in bone marrow transplantation for evaluation of T-cell reconstitution, and detection of host reactive and tumor-reactive T-cells (2004) (0)
GENOMIC ANALYSIS OF HEPATITIS C VIRUS INFECTION USING DNA MICROARRAYS. (1999) (0)
Assaying disease-specific gene expression by CDNA micro-arrays (1997) (0)
With DNA Microarrays Examining the Living Genome in Health and Disease (2010) (0)
Mediators of endothelial cell injury in low perfusion conditions (2004) (0)
Abstract 204: Molecular function of the RNA binding protein EWS in RNA processing (2012) (0)
Patterns of transcript abundance in whole-blood samples from children with KD (cohort 1) (2011) (0)
Response Letter --editor-1 – Abstract Too Long -- Excerpt from Revised Manuscript --editor-2 – Reference Style -- Reviewer Comment the Reference Articles Need Titles Excerpt from Revised Manuscript --editor-3 – Other Microarray Datasets (0)
Title Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer (2007) (0)
P17. Effects of tumor–stroma interaction on global gene expression in breast cancer (2006) (0)
interaction between tRNA(Lys) and an AAG lysine codon. the Escherichia coli dnaX gene and the role of an unstable Sequence requirements for efficient translational frameshifting in (2011) (0)
Impacts of high ATP supply from chloroplasts and mitochondria on the leaf metabolism of Arabidopsis thaliana (0)
Genome-wide study of human hepatocellular carcinoma with 23K cDNA microarray (2000) (0)
From gene expression to the bedside: A high-throughput approach for identifying serum diagnostic markers and immunotherapy targets in human malignancies using DNA microarrays (2001) (0)
Computational Methods and Bioinformatic Tools (2004) (0)
Analysis of gene expression in normal and malignant lymphocytes using the Lymphochip cDNA microarray (1999) (0)
Hypoxia gene expression signature in predicting outcome in breast cancer patients (2005) (0)
Clustering of KD samples on the basis of intrinsic gene-expression patterns (2011) (0)
Levels of mRNA in pretreatment whole-blood samples from KD patients who subsequently responded (R) o (2011) (0)
Gene-expression patterns reveal underlying biological processes inKawasaki disease (2007) (0)
GENOMIC ANALYSIS OF ACUTE ALLOGRAFT REJECTION USING DNA MICROARRAYS. (1999) (0)
Exploring along a Crooked Path * * Previously presented at the annual meeting of The American Socie (2006) (0)
Author response: miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway (2014) (0)
Gene Expression Patterns in Pancreatic Tumors, Cells and (2007) (0)
Genetic footprinting and functional maps of the yeast genome (1999) (0)
The New Atlantis and the Frontiers of Medicine THE A Modern-Day (2000) (0)
Investigating Differential Gene Expression in Anatomical Compartments of the Human Eye Using cDNA Microarrays (2004) (0)
Association of transcript abundance and clinical parameters in patients with acute KD (cohort 2) (2011) (0)
GENOMIC ANALYSIS OF HUMAN HEPATOCELLULAR CARCINOMA GENE EXPRESSION USING cDNA MICROARRAYS. (1999) (0)
The Temporal Gene Expression Patterns of Embryonic Hematopoiesis after Hemangioblast Commitment. (2005) (0)
TOWARDS A GENOMIC ANALYSIS OF TRANSPLANT IMMUNOBIOLOGY AND RELATED PHENOMENA. (1998) (0)
AN IN VITRO RNA AMPLIFICATION STRATEGY ALLOWS CDNA MICROARRAY ANALYSIS OF SMALL AMOUNTS OF TISSUE (1998) (0)
Variation in gene expression patterns in gastric cancer and discovery of prognostic biomarkers (2003) (0)
Genome-wide Analysis of Atopic Dermatitis (2008) (0)
WHOLE YEAST GENOME ANALYSIS USING DNA CHIPS (1999) (0)
Effects of tumor stroma interaction on global gene expression in breast cancer. (2006) (0)
A method and apparatus for manufacturing microarrays of biological samples (1995) (0)
2005 Curt Stern Award address. Exploring along a crooked path. (2006) (0)
Clonal origin of multiple nodular liver cancer (2001) (0)
Patterns of transcript abundance as a function of illness day (days post-onset of fever) (2011) (0)
Referees (2015) (0)
Identification of metastasis-associated genes in liver cancer (2002) (0)
Genome-wide expression profiling of hepatocellular carcinoma by cDNA microarray technology (2000) (0)
Identification of diagnostic markers / candidate therapeutic targets for liver cancer using cDNA microarray (2001) (0)
Molecular characterization of hepatocellular carcinoma by cDNA microarray (2001) (0)
Identification of metastasis-associated genes in hepatocellular carcinoma by cDNA microarray (2002) (0)
Non-dairy ricotta cheese replica (2014) (0)
An interview with Patrick O Brown on the origins and future of open access (2013) (0)
Short Takes on Long Poems (2012) (0)
EMail from Patrick O. Brown, Michael Eisen and Harold Varmus to Edward S. Yoon (2002) (0)

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