Patrick Schrauwen

Patrick Schrauwen's AcademicInfluence.com Rankings

Patrick Schrauwen

Biology

#9665

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#12895

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Biology

Patrick Schrauwen's Degrees

PhD Biomedical Sciences Maastricht University
Masters Biomedical Sciences Maastricht University
Bachelors Biomedical Sciences Maastricht University

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Patrick Schrauwen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cold-activated brown adipose tissue in healthy men. (2009) (3048)
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human (2012) (2790)
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. (2011) (1131)
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. (2013) (685)
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 (2011) (590)
Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus (2015) (415)
Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. (2004) (395)
Brown Adipose Tissue in Morbidly Obese Subjects (2011) (349)
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy (2013) (340)
Circadian clocks and insulin resistance (2018) (312)
Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients (2008) (310)
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. (1998) (306)
Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity (2009) (303)
The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity. (2015) (294)
The role of high-fat diets and physical activity in the regulation of body weight (2000) (277)
Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects (2006) (276)
Implications of nonshivering thermogenesis for energy balance regulation in humans. (2011) (266)
Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans (2015) (219)
Mitochondrial dysfunction and lipotoxicity. (2010) (217)
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. (2014) (213)
Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue (2017) (212)
UCP2 and UCP3 in muscle controlling body metabolism. (2002) (205)
Increase in brown adipose tissue activity after weight loss in morbidly obese subjects. (2012) (204)
Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats* (2010) (198)
Intramyocellular Lipid Content in Human Skeletal Muscle (2006) (196)
Regulation of metabolic transcriptional co‐activators and transcription factors with acute exercise (2005) (189)
Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids (2009) (185)
Systemic β-Adrenergic Stimulation of Thermogenesis Is Not Accompanied by Brown Adipose Tissue Activity in Humans (2012) (185)
Changes in fat oxidation in response to a high-fat diet. (1997) (182)
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation. (2013) (182)
Lipotoxicity in type 2 diabetic cardiomyopathy. (2011) (181)
An alternative function for human uncoupling protein 3: protection of mitochondria against accumulation of nonesterified fatty acids inside the mitochondrial matrix (2001) (176)
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus (2016) (174)
Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals (2010) (168)
A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle (2008) (166)
The journey of resveratrol from yeast to human (2012) (158)
Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD (2007) (156)
Low brown adipose tissue activity in endurance-trained compared with lean sedentary men (2015) (153)
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (151)
Brown adipose tissue activity after a high-calorie meal in humans. (2013) (151)
Muscular diacylglycerol metabolism and insulin resistance (2008) (142)
PPARgamma inhibits NF-kappaB-dependent transcriptional activation in skeletal muscle. (2009) (140)
Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance (2010) (140)
Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels (2012) (139)
The increase in intramyocellular lipid content is a very early response to training. (2003) (138)
Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians. (1999) (138)
Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus (2007) (137)
Cold-activated brown adipose tissue in human adults: methodological issues. (2014) (136)
The effect of a 3-month low-intensity endurance training program on fat oxidation and acetyl-CoA carboxylase-2 expression. (2002) (134)
Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake. (2008) (133)
Regulation of mitochondrial biogenesis during myogenesis (2010) (132)
Identification of human exercise-induced myokines using secretome analysis. (2014) (130)
Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle (2018) (130)
Uncoupling protein 3 as a mitochondrial fatty acid anion exporter (2003) (130)
High-fat diet, muscular lipotoxicity and insulin resistance (2007) (128)
A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians (1999) (127)
Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. (2012) (125)
TNF-alpha impairs regulation of muscle oxidative phenotype: implications for cachexia? (2010) (125)
A new validated endurance performance test. (2005) (124)
Human Skeletal Muscle Mitochondrial Uncoupling Is Associated with Cold Induced Adaptive Thermogenesis (2008) (123)
Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes. (2001) (116)
Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity (2016) (115)
The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men (2014) (114)
The role of uncoupling protein 3 in fatty acid metabolism: protection against lipotoxicity? (2004) (113)
Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise (2014) (113)
Intramyocellular lipid content and molecular adaptations in response to a 1-week high-fat diet. (2005) (111)
Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity. (2013) (110)
Resveratrol and obesity: Can resveratrol relieve metabolic disturbances? (2015) (108)
Serum FGF21 levels are associated with brown adipose tissue activity in humans (2015) (107)
Three weeks on a high-fat diet increases intrahepatic lipid accumulation and decreases metabolic flexibility in healthy overweight men. (2011) (107)
Increase in fat oxidation on a high-fat diet is accompanied by an increase in triglyceride-derived fatty acid oxidation. (2000) (106)
Putative function and physiological relevance of the mitochondrial uncoupling protein-3: involvement in fatty acid metabolism? (2006) (105)
Improved ejection fraction after exercise training in obesity is accompanied by reduced cardiac lipid content. (2010) (104)
Individual variation in body temperature and energy expenditure in response to mild cold. (2002) (101)
Pronounced Effects of Acute Endurance Exercise on Gene Expression in Resting and Exercising Human Skeletal Muscle (2012) (101)
Nine months of combined training improves ex vivo skeletal muscle metabolism in individuals with type 2 diabetes. (2013) (100)
Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial (2016) (99)
Energy metabolism in humans at a lowered ambient temperature (2002) (98)
Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1 alpha and PPAR beta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus. (2007) (97)
Adipocyte differentiation-related protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus. (2009) (92)
Human uncoupling proteins and obesity. (1999) (92)
Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers. (2001) (92)
Effect of acute exercise on uncoupling protein 3 is a fat metabolism-mediated effect. (2002) (92)
Glucose ingestion during exercise blunts exercise-induced gene expression of skeletal muscle fat oxidative genes. (2005) (91)
Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects. (2010) (91)
Skeletal muscle UCP2 and UCP3 expression in trained and untrained male subjects (1999) (90)
Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans (2014) (90)
Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes (2008) (90)
Muscle mitochondria and insulin resistance: a human perspective (2012) (89)
Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits? (2013) (88)
Circadian rhythms in mitochondrial respiration (2018) (88)
Energy dissipation in brown adipose tissue: From mice to men (2013) (87)
Metabolic availability of medium-chain triglycerides coingested with carbohydrates during prolonged exercise. (1995) (85)
Human uncoupling protein-3 and obesity: an update. (2003) (85)
Fiber type dependent upregulation of human skeletal muscle UCP2 and UCP3 mRNA expression by high-fat diet (2001) (85)
Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout mice. (2007) (84)
Imaging Cold-Activated Brown Adipose Tissue Using Dynamic T2*-Weighted Magnetic Resonance Imaging and 2-Deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography (2013) (83)
Role of glycogen-lowering exercise in the change of fat oxidation in response to a high-fat diet. (1997) (82)
PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans (2013) (80)
High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance (2012) (79)
Systemic inflammation correlates with increased expression of skeletal muscle ubiquitin but not uncoupling proteins in cancer cachexia. (2005) (79)
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity (2012) (78)
High-Fat Diet–Induced Mitochondrial Biogenesis Is Regulated by Mitochondrial-Derived Reactive Oxygen Species Activation of CaMKII (2014) (77)
Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients (2007) (77)
UCP3 protein expression is lower in type I, IIa and IIx muscle fiber types of endurance-trained compared to untrained subjects (2002) (76)
Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo. (2003) (76)
The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice (2008) (76)
Peroxisome proliferator-activated receptor-γ coactivator-1 and insulin resistance: acute effect of fatty acids (2006) (76)
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. (2016) (75)
Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise. (2015) (73)
Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus (2013) (72)
Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment. (2006) (70)
Uncoupling protein 3 and physical activity: the role of uncoupling protein 3 in energy metabolism revisited (2003) (70)
Modulation of myocellular fat stores: lipid droplet dynamics in health and disease. (2009) (69)
Effects of exercise training on intrahepatic lipid content in humans (2016) (69)
Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance (2014) (69)
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans (2020) (67)
Effect of beta1- and beta2-adrenergic stimulation on energy expenditure, substrate oxidation, and UCP3 expression in humans. (2003) (66)
Validation of the [1,2‐13C]acetate recovery factor for correction of [U‐13C]palmitate oxidation rates in humans (1998) (64)
Fat balance in obese subjects: role of glycogen stores. (1998) (64)
Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. (2009) (61)
Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis - A Cohort Study in a Group of Thyroid Carcinoma Patients (2016) (61)
Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high‐fat feeding (2008) (61)
Muscular mitochondrial dysfunction and type 2 diabetes mellitus (2007) (58)
Skeletal muscle mitochondrial uncoupling, adaptive thermogenesis and energy expenditure (2011) (57)
Effects of a high‐fat, low‐versus high‐glycemic index diet: retardation of insulin resistance involves adipose tissue modulation (2009) (57)
Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects (2013) (57)
Substrate oxidation differences between high- and low-intensity exercise are compensated over 24 hours in obese men (2004) (56)
Etomoxir‐induced increase in UCP3 supports a role of uncoupling protein 3 as a mitochondrial fatty acid anion exporter (2002) (55)
Effect of diet composition on leptin concentration in lean subjects. (1997) (54)
PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism. (2014) (54)
Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes (2018) (53)
Beta-adrenergic receptor blockade does not inhibit cold-induced thermogenesis in humans: possible involvement of brown adipose tissue. (2011) (53)
Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox (2018) (50)
Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle (2011) (50)
Determinants of the acetate recovery factor: implications for estimation of [13C]substrate oxidation. (2000) (50)
Combatting type 2 diabetes by turning up the heat (2016) (49)
Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. (2014) (49)
Exercise training restores uncoupling protein-3 content in limb muscles of patients with chronic obstructive pulmonary disease. (2006) (49)
Differential response of UCP3 to medium versus long chain triacylglycerols; manifestation of a functional adaptation (2003) (48)
Benefits of Substituting Sitting with Standing and Walking in Free-Living Conditions for Cardiometabolic Risk Markers, Cognition and Mood in Overweight Adults (2017) (48)
The effect of weight reduction on skeletal muscle UCP2 and UCP3 mRNA expression and UCP3 protein content in Type II diabetic subjects (2000) (47)
Reduced tricarboxylic acid cycle flux in type 2 diabetes mellitus? (2008) (47)
DGAT1 overexpression in muscle by in vivo DNA electroporation increases intramyocellular lipid content Published, JLR Papers in Press, December 1, 2004. DOI 10.1194/jlr.M400416-JLR200 (2005) (46)
Impaired skeletal muscle mitochondrial function in morbidly obese patients is normalized one year after bariatric surgery. (2013) (45)
Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction (2011) (44)
NAD+ metabolism as a target for metabolic health: have we found the silver bullet? (2019) (43)
Intramyocellular lipid droplets and insulin sensitivity, the human perspective. (2017) (43)
Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans (2016) (42)
Improved glucose homeostasis in mice overexpressing human UCP3: a role for AMP-kinase? (2004) (42)
Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. (2011) (42)
Uncoupling protein‐3 content is decreased in peripheral skeletal muscle of patients with COPD (2003) (42)
Prevention of high-fat diet-induced muscular lipid accumulation in rats by α lipoic acid is not mediated by AMPK activation[S] (2010) (41)
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance (2020) (41)
Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice (2012) (41)
Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver. (2018) (40)
Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein. (2015) (40)
Fat and carbohydrate balances during adaptation to a high-fat diet. (2000) (40)
Peroxisome proliferator-activated receptors: a therapeutic target in COPD? (2008) (39)
Exercise-induced modulation of cardiac lipid content in healthy lean young men (2010) (39)
The insulin-sensitizing effect of rosiglitazone in type 2 diabetes mellitus patients does not require improved in vivo muscle mitochondrial function. (2008) (39)
The future of brown adipose tissues in the treatment of type 2 diabetes (2015) (38)
Skeletal muscle uncoupling protein 3 (UCP3): mitochondrial uncoupling protein in search of a function (2002) (37)
Shift in metabolic fuel in acylation-stimulating protein-deficient mice following a high-fat diet. (2008) (37)
Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. (2013) (36)
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function (2021) (36)
Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and Caucasians in the arctic winter (2015) (36)
Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy. (2013) (36)
Decreased uncoupling protein expression and intramyocytic triglyceride depletion in formerly obese subjects. (2003) (35)
Acute exercise does not decrease liver fat in men with overweight or NAFLD (2015) (35)
Diet and nonalcoholic fatty liver disease (2008) (35)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (35)
Energy balance in a respiration chamber: individual adjustment of energy intake to energy expenditure (1997) (34)
Enhanced lipid—but not carbohydrate—supported mitochondrial respiration in skeletal muscle of PGC‐1α overexpressing mice (2012) (33)
The effect of mild cold exposure on UCP3 mRNA expression and UCP3 protein content in humans (2002) (33)
No effect of resveratrol supplementation after 6 months on insulin sensitivity in overweight adults: a randomized trial (2020) (33)
Mitochondrial dynamics, quality control and miRNA regulation in skeletal muscle: implications for obesity and related metabolic disease. (2016) (33)
Chemical imaging of lipid droplets in muscle tissues using hyperspectral coherent Raman microscopy (2013) (33)
Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial (2017) (33)
Differential effects of saturated versus unsaturated dietary fatty acids on weight gain and myocellular lipid profiles in mice (2011) (32)
Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes (2016) (31)
Adaptations in Mitochondrial Function Parallel, but Fail to Rescue, the Transition to Severe Hyperglycemia and Hyperinsulinemia: A Study in Zucker Diabetic Fatty Rats (2010) (30)
Involvement of UCP3 in mild uncoupling and lipotoxicity (2006) (30)
Long- and medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation. (2012) (30)
Geometrical models for cardiac MRI in rodents: comparison of quantification of left ventricular volumes and function by various geometrical models with a full-volume MRI data set in rodents. (2012) (30)
Acylation-stimulating protein: effect of acute exercise and endurance training (2005) (30)
The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice (2018) (29)
The use of the [1,2-13C]acetate recovery factor in metabolic research (2003) (29)
Regional variations in intramyocellular lipid concentration correlate with muscle fiber type distribution in rat tibialis anterior muscle (2006) (29)
Decreased fatty acid beta-oxidation in riboflavin-responsive, multiple acylcoenzyme A dehydrogenase-deficient patients is associated with an increase in uncoupling protein-3. (2003) (29)
Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes. (2017) (29)
Effect of 2 weeks of endurance training on uncoupling protein 3 content in untrained human subjects. (2005) (28)
Exercise counteracts lipotoxicity by improving lipid turnover and lipid droplet quality (2018) (28)
Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5? (2017) (28)
The use of statins potentiates the insulin-sensitizing effect of exercise training in obese males with and without Type 2 diabetes. (2010) (27)
Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans (2020) (26)
High-fat diets rich in medium- versus long-chain fatty acids induce distinct patterns of tissue specific insulin resistance. (2011) (26)
Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging (2015) (26)
Transcriptional Metabolic Inflexibility in Skeletal Muscle Among Individuals With Increasing Insulin Resistance (2011) (25)
The Effects of Different Degrees of Carbohydrate Restriction and Carbohydrate Replacement on Cardiometabolic Risk Markers in Humans—A Systematic Review and Meta-Analysis (2020) (25)
A role of active brown adipose tissue in cancer cachexia? (2012) (25)
Mitochondrial Function and Diabetes: Consequences for Skeletal and Cardiac Muscle Metabolism. (2016) (25)
The effect of high‐fat feeding on intramuscular lipid and lipid peroxidation levels in UCP3‐ablated mice (2006) (25)
Skeletal muscle in healthy humans exhibits a day-night rhythm in lipid metabolism (2020) (25)
Can resveratrol help to maintain metabolic health? (2014) (24)
Reduced Incorporation of Fatty Acids Into Triacylglycerol in Myotubes From Obese Individuals With Type 2 Diabetes (2014) (24)
Stimulation of human whole-body energy expenditure by salsalate is fueled by higher lipid oxidation under fasting conditions and by higher oxidative glucose disposal under insulin-stimulated conditions. (2011) (24)
PPARγ activity in subcutaneous abdominal fat tissue and fat mass gain during short-term overfeeding (2006) (24)
Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity. (2018) (24)
Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial (2021) (23)
The effect of etomoxir on 24-h substrate oxidation and satiety in humans. (2002) (23)
Passive exposure to heat improves glucose metabolism in overweight humans (2020) (23)
Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans (2018) (23)
ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity (2016) (23)
Evaluation of Muscle microRNA Expression in Relation to Human Peripheral Insulin Sensitivity: A Cross-Sectional Study in Metabolically Distinct Subject Groups (2017) (23)
Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity (2020) (22)
Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome. (2012) (22)
Exercising your fat (metabolism) into shape: a muscle-centred view (2020) (22)
Skeletal muscle uncoupling protein‐3 restores upon intervention in the prediabetic and diabetic state: implications for diabetes pathogenesis? (2007) (22)
Ticking for Metabolic Health: The Skeletal‐Muscle Clocks (2020) (21)
Significance of uncoupling protein 3 in mitochondrial function upon mid‐ and long‐term dietary high‐fat exposure (2011) (21)
Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men. (2011) (20)
The Effects of Long‐ or Medium‐Chain Fat Diets on Glucose Tolerance and Myocellular Content of Lipid Intermediates in Rats (2011) (20)
An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism (2017) (20)
Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity. (2018) (20)
Diet and glycaemia: the markers and their meaning. A report of the Unilever Nutrition Workshop (2014) (19)
Towards comprehension of the physiological role of UCP3. (2005) (19)
Increased intramyocellular lipids but unaltered in vivo mitochondrial oxidative phosphorylation in skeletal muscle of adipose triglyceride lipase-deficient mice. (2012) (18)
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue (2019) (18)
UCP3 in muscle wasting, a role in modulating lipotoxicity? (2006) (17)
Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue. (2011) (16)
PPAR inhibits NF- B-dependent transcriptional activation in skeletal muscle (2009) (16)
Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals (2020) (15)
Prolonged Fasting and the Effects on Biomarkers of Inflammation and on Adipokines in Healthy Lean Men (2012) (15)
The adaptation of nutrient oxidation to nutrient intake on a high-fat diet (1997) (15)
Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes (2022) (14)
Quantum coherence spectroscopy to measure dietary fat retention in the liver. (2016) (14)
Intramyocellular lipids and insulin sensitivity: does size really matter? (2004) (14)
Uncoupling proteins in the failing human heart: friend or foe? (2005) (14)
Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death (2014) (14)
Atrial Natriuretic Peptide Orchestrates a Coordinated Physiological Response to Fuel Non-shivering Thermogenesis. (2020) (13)
Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing (2020) (13)
TNF‐α impairs regulation of muscle oxidative phenotype: implications for cachexia? (2010) (13)
Short-term training is accompanied by a down regulation of ACC2 mRNA in skeletal muscle. (2006) (13)
Genomic and transcriptomic predictors of triglyceride response to regular exercise (2015) (13)
Healthy aging and muscle function are positively associated with NAD+ abundance in humans (2022) (12)
Elevated plasma branched-chain amino acid levels correlate with type 2 diabetes-related metabolic disturbances. (2020) (12)
A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes (2022) (12)
High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice. (2010) (12)
One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension (2020) (12)
Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity. (2018) (11)
Resveratrol: Challenges in translating pre-clinical findings to improved patient outcomes. (2015) (11)
Longitudinal relaxation time editing for acetylcarnitine detection with 1H‐MRS (2017) (10)
Relationship of C5L2 Receptor to Skeletal Muscle Substrate Utilization (2013) (10)
Divergent effects of acute exercise and endurance training on UCP3 expression. (2003) (10)
Effects of dietary macronutrients on liver fat content in adults: a systematic review and meta-analysis of randomized controlled trials (2020) (10)
Anti-inflammatory effect of rosiglitazone is not reflected in expression of NFκB-related genes in peripheral blood mononuclear cells of patients with type 2 diabetes mellitus (2009) (9)
Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop (2017) (9)
Metabolic responses to mild cold acclimation in type 2 diabetes patients (2021) (9)
Type 2 diabetes subgroups and potential medication strategies in relation to effects on insulin resistance and beta-cell function: A step toward personalised diabetes treatment? (2020) (9)
No evidence for brown adipose tissue activation after creatine supplementation in adult vegetarians (2021) (9)
Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: a randomised crossover trial (2022) (9)
Lipotoxicity and Mitochondrial Dysfunction in Type 2 Diabetes (2007) (9)
Eat the meat or feed the meat: protein turnover in remodeling muscle (2006) (8)
Physical activity and diabetes: current considerations. (2007) (7)
Core-skin gradient of body temperature related to non-shivering thermogenesis 3 in humans at a lowered ambient temperature (2001) (7)
Relationship between de novo lipogenesis and serum sex hormone binding globulin in humans (2021) (7)
A genistein-enriched diet neither improves skeletal muscle oxidative capacity nor prevents the transition towards advanced insulin resistance in ZDF rats (2016) (7)
NAD+-Precursor Supplementation With L-Tryptophan, Nicotinic Acid, and Nicotinamide Does Not Affect Mitochondrial Function or Skeletal Muscle Function in Physically Compromised Older Adults (2021) (7)
Blocking the Entrance to Open the Gate (2013) (7)
Effects of a whole diet approach on metabolic flexibility, insulin sensitivity and postprandial glucose responses in overweight and obese adults - A randomized controlled trial. (2019) (7)
Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women (2021) (6)
The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day (2022) (6)
The effect of beta-adrenergic blockade on non-esterified fatty acid uptake of exercising skeletal muscle during arm cranking. (1995) (6)
The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity (2021) (6)
Decoration of myocellular lipid droplets with perilipins as a marker for in vivo lipid droplet dynamics: A super-resolution microscopy study in trained athletes and insulin resistant individuals. (2020) (5)
Hyperglycemic diet and training alter insulin sensitivity, intramyocellular lipid content but not UCP3 protein expression in rat skeletal muscles. (2010) (5)
Cold acclimation and health: effect on brown fat, energetics, and insulin sensitivity (2015) (5)
Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers (2020) (5)
Resveratrol treatment does not reduce arterial inflammation in males at risk of type 2 diabetes: a randomized crossover trial. (2021) (5)
Lipid-induced cell stress and insulin resistance (2006) (5)
Effect of 1-and 2-adrenergic stimulation on energy expenditure , substrate oxidation , and UCP 3 expression in humans (2003) (5)
Athletes feature greater rates of muscle glucose transport and glycogen synthesis during lipid infusion. (2019) (5)
Atrial natriuretic peptide orchestrates a coordinated physiological response to fuel non shivering thermogenesis (2019) (5)
Circadian misalignment disturbs the skeletal muscle lipidome in healthy young men (2021) (5)
Nicotinamide riboside enhances in vitro beta-adrenergic brown adipose tissue activity in humans. (2021) (4)
Perspectives in Diabetes Oxidative Capacity , Lipotoxicity , and Mitochondrial Damage in Type 2 Diabetes (2004) (4)
The effect of cold exposure with shivering on glucose tolerance in healthy men. (2020) (3)
Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training (2021) (3)
Circulating 1,5-anhydroglucitol as a biomarker of ß-cell mass independent of a diabetes phenotype in human subjects. (2022) (3)
Of the fit and the fat: mitochondrial abnormalities and type 2 diabetes mellitus. (2007) (3)
Liver fat storage pathways: methodologies and dietary effects (2020) (3)
Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers (2001) (2)
Effect of Diet Composit ion on Leptin Concentrat ion in Lean Subjects (2004) (2)
Effect of mild cold on metabolic and insulative adaptation in man (2001) (2)
Resveratrol‐induced remodelling of myocellular lipid stores: A study in metabolically compromised humans (2021) (2)
Mild Exercise Does Not Prevent Atherosclerosis in APOE*3‐Leiden.CETP Mice or Improve Lipoprotein Profile of Men with Obesity (2020) (2)
Determinants of Energy and Substrate Metabolism (1998) (2)
Dietary fat and obesity. (2006) (2)
TSH suppression aggravates arterial inflammation — an 18F-FDG PET study in thyroid carcinoma patients (2019) (2)
Timing of physical activity in relation to liver fat content and insulin resistance (2022) (2)
The effect of diet composition on acetate recovery factor during rest and exercise (1999) (1)
Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial (2023) (1)
Correction: Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis—A Cohort Study in a Group of Thyroid Carcinoma Patients (2018) (1)
EXERCISE, TEMPERATURE REGULATION (2003) (1)
A Whole-Diet Approach Affects Not Only Fasting but Also Postprandial Cardiometabolic Risk Markers in Overweight and Obese Adults: A Randomized Controlled Trial (2020) (1)
Effects of high‐fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring (2015) (1)
Fat balance in obese subjects: role of glycogen stores. (1998) (1)
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (1)
PS5 - 26. Exposure to a high fat diet during early development increases the susceptibility to cardiac lipid accumulation (2012) (1)
Lipids in metabolic health and disease. (2011) (1)
In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes (2019) (1)
L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility (2020) (1)
The importance of 24-h metabolism in obesity-related metabolic disorders: opportunities for timed interventions (2020) (1)
Differences in acetate recovery factor between groups may interfere with tracer estimates of fact oxidation. (2001) (1)
Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men. (2022) (1)
OXIDATION OF ORALLY INGESTED MEDIUM CHAIN TRIGLYCERIDE (MCT) DURING PROLONGED EXERCISE: 571 (1995) (1)
PO 78ADRP and OXPAT protein content in muscular lipid accumulation and insulin resistance (2008) (1)
Novel insights in intestinal and hepatic fructose metabolism: from mice to men (2022) (1)
Circadian misalignment induces insulin resistance and elevated glucose and FFA levels : a randomised crossover trial (2017) (0)
Low oxidation of branched-chain amino acids in people with type 2 diabetes may underlie increased systemic levels (2017) (0)
The changing landscape of scientific communication at EASD (2022) (0)
PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance (2012) (0)
A molecular signature linked to calcium signalling is predictive of exercise training-induced changes in insulin sensitivity (2016) (0)
Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism (2022) (0)
Therapeutic Efficiency of Lowering Branched-Chain Amino Acid Levels in Patients with Type 2 Diabetes Using Sodium-Phenylbutyrate: A Randomized Placebo Controlled Clinical Intervention Study (2021) (0)
Physical inactivity lowers mitochondrial oxidative capacity and predisposes to muscle fat accumulation and lipid-induced insulin resistance (2017) (0)
Replacing Foods with a High-Glycemic Index and High in Saturated Fat by Alternatives with a Low Glycemic Index and Low Saturated Fat Reduces Hepatic Fat, Even in Isocaloric and Macronutrient Matched Conditions (2023) (0)
PPAR‐γ activation inhibits TNF‐α induced NF‐κB activity in skeletal muscle (2008) (0)
Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans (2022) (0)
PCr/ATP Ratios and Mitochondrial Function in The Heart. A Comparative Study in Humans. (2021) (0)
Workshop 2 O7–O12 (2001) (0)
Brown adipose tissue: The magic bullet? (2017) (0)
Response to Comment on Timmers et al. Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care 2016;39:2211–2217 (2017) (0)
METABOLIC RESPONSE TO CARBOHYDRATE-FAT SUPPLEMENTATION DURING PROLONGED EXERCISE: 1197 (1995) (0)
Uncoupling protein 3 and the protection of skeletal muscle mitochondrial function; a transgenic approach (2006) (0)
High protein levels of PLIN2 and low levels of ATGL are associated with insulin resistance and low number of intramyocellular lipid droplets (2017) (0)
Elevated Free Fatty Acids Caloric Restriction and Exercise Increase Plasma ANGPTL 4 Levels in Humans (2009) (0)
Erratum. Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial. Diabetes Care 2021;44:1334-1343. (2022) (0)
PS10 - 1. Fatty acid inducible myokine ANGPTL4 governs the lipid metabolic response to acute exercise (2013) (0)
PO 72Mitochondrial respiration in skeletal muscle from Zucker Diabetic Fatty rats (2008) (0)
Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus (2009) (0)
Athletes Are Resistant to Lipid-Induced Insulin Resistance by Maintaining Higher Rates of Muscle Glucose Uptake and Glycogen Synthesis (2017) (0)
Chapter 6: High levels of whole body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57Bl/6 mice (2010) (0)
Diet or diet plus physical activity in patients with early type 2 diabetes (2011) (0)
Circadian misalignment induces fatty acid metabolism gene profiles and induces insulin resistance in human skeletal muscle (2018) (0)
exercise-induced muscle damage Cellular adaptation to repeated eccentric (2015) (0)
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance (2020) (0)
PS3 - 17. Maternal high-fat intake and the effect of imprinting on hepatic mitochondrial function in offspring (2012) (0)
Post-exercise changes in myocellular lipid droplet characteristics of young lean individuals are affected by circulatory non-esterified fatty acids. (2021) (0)
Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (0)
Comparative transcriptome analysis of human skeletal muscle in response to cold acclimation and exercise training in human volunteers (2020) (0)
Editorial; Lipids in Metabolic Health and Disease (2012) (0)
Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity (2023) (0)
Explorer A reservoir of brown adipocyte progenitors in human skeletal muscle (2017) (0)
athletesvs. single bouts of prolonged cycling in elite Enhanced plasma IL-6 and IL-1ra responses to (2015) (0)
Circadian Rhythmicity of Skeletal Muscle Metabolism (2019) (0)
Underpowered or negative? A crucial distinction. Reply to Dollerup OL, Treebak JT, Jessen N [letter] (2019) (0)
Skeletal muscle as a thermogenic organ (2002) (0)
lipolysis during long-lasting exercise in trained men Effect of carbohydrate ingestion on adipose tissue (2015) (0)
THE EFFECT OF GLYCOGEN LOWERING EXERCISE AND DIET COMPOSITION ON FAT OXIDATION 1134 (1997) (0)
PS7 - 40. High IMCL turnover may explain the athlete’s paradox (2011) (0)
PS14 - 72. The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (0)
Investigating The Effectiveness Of A Healthy Diet On Metabolic Flexibility And Insulin Sensitivity - A Challenge-Based Human Trial (2019) (0)
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue (2019) (0)
Cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. (2015) (0)
Lipotoxicity in heart and skeletal muscle: MRI / MRS studies (2009) (0)
Cardiac lipid content is reduced after twelve weeks of endurance and strength training in overweight subjects (2008) (0)
Conference on ‘ Nutrition and healthy ageing ’ Symposium 3: Nutrition modulation of the ageing trajectory Can resveratrol help to maintain metabolic health? (2014) (0)
[Detaching proteins in humans: regulators of energy balance or substrate metabolism? [special excess weight]] (2000) (0)
TNF-α Impairs Regulation of Skeletal Muscle Oxidative Capacity through Activation of NF-κB. (2009) (0)
PS14 - 70. C5L2- a potential regulator of skeletal muscle lipid accumulation (2011) (0)
expenditure in response to mild cold Individual variation in body temperature and energy (2016) (0)
Muscle Clocks and Diabetes (2020) (0)
The E ﬀ ects of Di ﬀ erent Degrees of Carbohydrate Restriction and Carbohydrate Replacement on Cardiometabolic Risk Markers in Humans—A Systematic Review and Meta-Analysis (2020) (0)
S12.29 Mitochondrial respiration in skeletal muscle from Zucker Diabetic Fatty rats (2008) (0)
Physiological significance of uncoupling protein-3: a role in fatty acid handling? (2003) (0)
Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial. (2022) (0)
The role of lipids in the development of insulin resistance (2005) (0)
Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein 1 – 3 (2014) (0)
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (2018) (0)
Effect of maternal exposure to high fat feeding on cardiac metabolism and function in offspring (2012) (0)
Cardiac lipid content increases upon exercise-induced elevation of plasma fatty acid concentrations (2010) (0)
Peroxisome proliferator-activated receptor expression is reduced in skeletal muscle in COPD. Commentary (2007) (0)
Silver Medal Lecture High-fat diet, muscular lipotoxicity and insulin resistance (2007) (0)
Mild cold and overfeeding adaptive thermogenesis: role of mitochondrial uncoupling (2008) (0)
PS3 - 14. The effect of the exercise-induced muscle secretome on liver gene expression (2012) (0)
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria (2011) (0)
Insulin resistance and mitochondrial function; a mitocentric view (2005) (0)
Chemical imaging of lipid droplets in muscle tissues using hyperspectral coherent Raman microscopy (2013) (0)
Investigating The Effectiveness Of A Healthy Diet On Cardiovascular Risk Markers - A Challenge-Based Human Trial (2019) (0)
PS7 - 38. Effects of acute endurance exercise on gene expression in skeletal muscle (2011) (0)
PS4 - 21. IP/OP MR Imaging as an alternative for 1H-MRS to measure Intrahepatic lipid (2011) (0)
Author's response to reviews Title: Anti-inflammatory effect of rosiglitazone is not reflected in expression of NFkappaB-related genes in peripheral blood mononuclear cells of patients with type 2 diabetes mellitus Authors: (2009) (0)
PPAR-{gamma} activation inhibits TNF-{alpha} induced NF-{kappa}B activity in skeletal muscle (2008) (0)
PS7 - 37. Effects of acute exercise on hepatic lipid content (2011) (0)
The role of uncoupling protein-3 in type 2 diabetes mellitus in humans (2002) (0)
No evidence for brown adipose tissue activation after creatine supplementation in adult vegetarians (2021) (0)
PS5 - 29. Increased intramyocellular lipid storage capacity is associated with lower fasting-induced insulin resistance (2012) (0)
PS14 - 71. Increased intramyocellular lipids, but normal muscular mitochondrial oxidative capacity in adipose triglyceride lipase deficient mice (2011) (0)
Effect of (cid:1) 1 - and (cid:1) 2 -adrenergic stimulation on energy expenditure, substrate oxidation, and UCP3 expression in humans (2003) (0)
Differential effects of diets rich in medium- versus long chain triacylglycerols on muscular lipid and acylcarnitine content do not affect glucose tolerance in rats (2008) (0)
A prolonged fast improves overnight substrate oxidation without modulating hepatic glycogen in adults with and without nonalcoholic fatty liver: A randomized crossover trial (2023) (0)

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What Schools Are Affiliated With Patrick Schrauwen?

Patrick Schrauwen is affiliated with the following schools:

Maastricht University