Patrick Vallance
#9,005
Most Influential Person Now
Chief Scientific Adviser to the UK Government
Why Is Patrick Vallance Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir Patrick John Thompson Vallance is a British physician, scientist, and clinical pharmacologist who has worked in both academia and industry. He served as the Chief Scientific Adviser to the Government of the United Kingdom from 2018 to 2023.
Patrick Vallance's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. (2002) (4629)
- Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure (1992) (2163)
- EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN (1989) (1676)
- Treatment of periodontitis and endothelial function. (2007) (1189)
- Risk of myocardial infarction and stroke after acute infection or vaccination. (2004) (1071)
- Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock (1991) (887)
- Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis (2005) (664)
- Hyperdynamic circulation in cirrhosis: a role for nitric oxide? (1991) (652)
- Acute Systemic Inflammation Impairs Endothelium-Dependent Dilatation in Humans (1999) (622)
- Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. (1992) (558)
- Cardiovascular Biology of the Asymmetric Dimethylarginine:Dimethylarginine Dimethylaminohydrolase Pathway (2004) (554)
- Effects of a nitric oxide synthase inhibitor in humans with septic shock. (1994) (547)
- Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia (2003) (513)
- Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis (1992) (471)
- Asymmetric Dimethylarginine Causes Hypertension and Cardiac Dysfunction in Humans and Is Actively Metabolized by Dimethylarginine Dimethylaminohydrolase (2003) (469)
- Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. (1999) (468)
- Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. (1999) (457)
- Measuring forearm blood flow and interpreting the responses to drugs and mediators. (1995) (446)
- Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. (1997) (432)
- Heterogenous Nature of Flow-Mediated Dilatation in Human Conduit Arteries In Vivo: Relevance to Endothelial Dysfunction in Hypercholesterolemia (2001) (422)
- Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting (2006) (422)
- Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase (1996) (404)
- Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal. (1992) (389)
- Disruption of methylarginine metabolism impairs vascular homeostasis (2007) (389)
- Endothelial function and nitric oxide: clinical relevance (2001) (388)
- Dimethylarginine Dimethylaminohydrolase Regulates Nitric Oxide Synthesis: Genetic and Physiological Evidence (2003) (347)
- Infection, inflammation, and infarction: does acute endothelial dysfunction provide a link? (1997) (337)
- Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo. (2001) (334)
- Blocking NO synthesis: how, where and why? (2002) (309)
- S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase (2002) (302)
- Erratum: Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. A report of the international brachial artery reactivity task force (Journal of American College of Cardiology (2002) 39 (257-265)) (2002) (276)
- Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. (2004) (263)
- Platelet adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide. (1993) (233)
- Measurement of nitrite and nitrate levels in plasma and urine--what does this measure tell us about the activity of the endogenous nitric oxide system? (1998) (232)
- Nitric oxide-mediated vasodilation in human pregnancy. (1997) (214)
- Elevated C‐reactive protein and pro‐inflammatory cytokines in Andean women with pre‐eclampsia (2001) (205)
- The DDAH/ADMA/NOS pathway. (2003) (202)
- Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. (2000) (201)
- Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney. (1997) (200)
- Inflammation and Endothelial Function: Direct Vascular Effects of Human C-Reactive Protein on Nitric Oxide Bioavailability (2005) (181)
- Nitric oxide and cardiovascular control (1993) (180)
- Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation. (1994) (176)
- Endothelial "stunning" following a brief exposure to endotoxin: a mechanism to link infection and infarction? (1996) (169)
- Concentration of dimethyl-L-arginine in the plasma of patients with end-stage renal failure (1996) (169)
- Prevention of Inflammation-Induced Endothelial Dysfunction: A Novel Vasculo-Protective Action of Aspirin (2002) (168)
- Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis (1994) (168)
- Endothelial Nitric Oxide Gene Haplotypes and Risk of Cerebral Small-Vessel Disease (2004) (167)
- Direct measurement of nitric oxide in human beings (1995) (166)
- Plasma concentrations of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and pre-eclampsia (1993) (164)
- Effects of guanidino and uremic compounds on nitric oxide pathways. (1994) (161)
- Nitric oxide synthase inhibition in humans reduces cerebral blood flow but not the hyperemic response to hypercapnia. (1998) (160)
- Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase (2001) (153)
- Fortnightly Review Biology and clinical relevance of nitric oxide (1994) (152)
- Role of endogenous nitric oxide in septic shock. (1993) (147)
- all-trans-Retinoic Acid Increases Nitric Oxide Synthesis by Endothelial Cells: A Role for the Induction of Dimethylarginine Dimethylaminohydrolase (2002) (143)
- Effect of inhibition of nitric oxide synthase on dynamic cerebral autoregulation in humans. (2000) (140)
- Metabolism of Asymmetric Dimethylarginines Is Regulated in the Lung Developmentally and With Pulmonary Hypertension Induced by Hypobaric Hypoxia (2003) (140)
- Endothelial NO Synthase Genotype and Risk of Preeclampsia: A Multicenter Case-Control Study (2004) (138)
- Second messenger role for NO widens to nervous and immune systems. (1989) (136)
- Induction of NG-monomethyl-L-arginine uptake: a mechanism for differential inhibition of NO synthases? (1995) (133)
- Isoform-Specific Regulation by NG,NG-Dimethylarginine Dimethylaminohydrolase of Rat Serum Asymmetric Dimethylarginine and Vascular Endothelium-Derived Relaxing Factor/NO (2007) (131)
- A simple computer program for guiding management of cardiovascular risk factors and prescribing (1999) (131)
- Genetic and Environmental Determinants of Plasma Nitrogen Oxides and Risk of Ischemic Heart Disease (2001) (130)
- Nitric oxide and vascular responses in Type I diabetes (2000) (121)
- Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity. (1999) (119)
- Laser Doppler flowmetry detection of endothelial dysfunction in end-stage renal disease patients: correlation with cardiovascular risk. (2006) (116)
- Importance of asymmetrical dimethylarginine in cardiovascular risk (2001) (114)
- Human Cytomegalovirus Seropositivity Is Associated With Impaired Vascular Function (2003) (114)
- Science as a public enterprise: the case for open data (2011) (112)
- Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis (2007) (111)
- Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. (1989) (110)
- Effect of local intra-arterial asymmetric dimethylarginine (ADMA) on the forearm arteriolar bed of healthy volunteers. (1993) (109)
- Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse. (2000) (108)
- Endothelial Nitric Oxide Synthase Gene Polymorphism and Maternal Vascular Adaptation to Pregnancy (2001) (108)
- Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. (2003) (100)
- Dilator actions of arginine in human peripheral vasculature. (1991) (98)
- The ADMA/DDAH pathway is a critical regulator of endothelial cell motility (2007) (95)
- Nitric oxide: therapeutic opportunities (2003) (93)
- The synthesis and metabolism of asymmetric dimethylarginine (ADMA) (2006) (92)
- Endothelin receptors mediating functional responses in human small arteries and veins (1994) (91)
- Cardiovascular risk factors as determinants of endothelium-dependent and endothelium-independent vascular reactivity in the general population. (2001) (90)
- Dialysis improves endothelial function in humans. (2001) (87)
- Synthesis of NG, NG Dimethylarginine by Human Endothelial Cells (1993) (86)
- Cardiovascular risk and diabetes. Are the methods of risk prediction satisfactory? (2004) (85)
- Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. (1989) (84)
- Local L-NG-monomethyl-arginine attenuates the vasodilator action of bradykinin in the human forearm. (1994) (84)
- Four principles to make evidence synthesis more useful for policy (2018) (84)
- Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. (2003) (81)
- Differential Effect of Three Cyclooxygenase Inhibitors on Human Cerebral Blood Flow Velocity and Carbon Dioxide Reactivity (1994) (80)
- Vascular and hormonal responses to arginine: provision of substrate for nitric oxide or non-specific effect? (1995) (77)
- Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. (1999) (77)
- Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology. (2000) (73)
- Endothelium-Dependent and -Independent Vascular Dysfunction in Type 1 Diabetes: Role of Conventional Risk Factors, Sex, and Glycemic Control (2003) (72)
- Effects of ADMA upon Gene Expression: An Insight into the Pathophysiological Significance of Raised Plasma ADMA (2005) (70)
- Local venous responses to endotoxin in humans. (1996) (70)
- Pulmonary Hypertension in a GTP-Cyclohydrolase 1–Deficient Mouse (2005) (68)
- Periodontal therapy: a novel non-drug-induced experimental model to study human inflammation. (2004) (68)
- Protease-Activated Receptor 2–Mediated Vasodilatation in Humans In Vivo: Role of Nitric Oxide and Prostanoids (2003) (67)
- Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. (2003) (66)
- Concentration of dimethyl-L-arginine in the plasma of patients with end-stage renal failure. (1996) (65)
- Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store (1998) (63)
- Relative potency and arteriovenous selectivity of nitrovasodilators on human blood vessels: an insight into the targeting of nitric oxide delivery. (1995) (62)
- Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. (2001) (60)
- Effects of aldosterone receptor blockade in patients with mild–moderate heart failure taking a beta‐blocker (2007) (59)
- Carriage of the V279F Null Allele within the Gene Encoding Lp-PLA2 Is Protective from Coronary Artery Disease in South Korean Males (2011) (56)
- Chronic Stress Accelerates Atherosclerosis in the Apolipoprotein E Deficient Mouse (2003) (56)
- Effects of cytokines on nitric oxide pathways in human vasculature. (1999) (56)
- The Effect of the Nitric Oxide Synthase Inhibitor L-NMMA on Basal CBF and Vasoneuronal Coupling in Man: A PET Study (1999) (55)
- The vascular endothelium in diabetes and hypertension. (1992) (54)
- Asymmetric Dimethylarginine in Cerebral Small Vessel Disease (2007) (53)
- Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase. (2005) (52)
- Physiological importance of nitric oxide. (1991) (51)
- Human saphenous vein contains both endothelin ETA and ETB contractile receptors. (1994) (50)
- Nitric oxide: an endogenous gas. (1995) (50)
- Endogenous production of nitric oxide synthase inhibitors (2005) (48)
- Nitric oxide in essential and renal hypertension. (1994) (48)
- Deletion of the eNOS gene has a greater impact on the pulmonary circulation of male than female mice. (2005) (47)
- Renal artery stenosis masquerading as congestive heart failure (1993) (47)
- The effect of malnutrition on cardiovascular mortality in dialysis patients: is L-arginine the answer? (1994) (46)
- Nitric Oxide - From Mediator to Medicines (1994) (46)
- New tricks from an old dog: nitric oxide-independent effects of dimethylarginine dimethylaminohydrolase. (2006) (45)
- The future of pharmacology (2006) (45)
- Nitric Oxide 9 Years On (1996) (44)
- Dose- and time-dependency of the dilator effects of the endothelin antagonist, BQ-123, in the human forearm. (2003) (43)
- Effect of local inhibition of nitric oxide synthesis on forearm blood flow and dorsal hand vein size in patients with alcoholic cirrhosis. (1994) (43)
- Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology (1999) (40)
- What is the optimal age for starting lipid lowering treatment? A mathematical model (2000) (39)
- Nitric oxide and blood pressure: effects of nitric oxide deficiency (1996) (37)
- Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2. (2010) (36)
- The role of induction of nitric oxide synthesis in the altered responses of jugular veins from endotoxaemic rabbits (1992) (36)
- Forearm blood flow responses to a nitric oxide synthase inhibitor in patients with treated essential hypertension. (1994) (36)
- Biphasic response to acetylcholine in human veins in vivo: the role of the endothelium. (1990) (36)
- Vasodilatation to arachidonic acid in humans. An insight into endogenous prostanoids and effects of aspirin. (1995) (35)
- Flow associated or flow mediated dilatation? More than just semantics. (1997) (35)
- Effect of anti‐fungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase (1994) (34)
- Endothelium‐derived relaxing factor is an endogenous vasodilator in man (1989) (33)
- L-arginine-induced hypotension (1990) (32)
- Asymmetric dimethylarginine and kidney disease--marker or mediator? (2005) (32)
- Endothelial regulation of vascular tone. (1992) (32)
- Individual Gestalt Is Unreliable for the Evaluation of Quality in Medical Education Blogs: A METRIQ Study (2017) (32)
- ADMA regulates angiogenesis: genetic and metabolic evidence (2005) (32)
- On the regulation of tone in vasa vasorum. (1999) (31)
- Endothelial nitric oxide in humans in health and disease (1999) (31)
- Plasma nitrite as a marker of nitric oxide production (1994) (30)
- Tyrosine nitration in blood vessels occurs with increasing nitric oxide concentration (1999) (30)
- Effect of acute plasma volume expansion on peripheral arteriolar tone in healthy subjects. (1992) (30)
- The Future Is Much Closer Collaboration Between the Pharmaceutical Industry and Academic Medical Centers (2010) (29)
- Positive inotropic effects of NO donors in isolated guinea-pig and human cardiomyocytes independent of NO species and cyclic nucleotides. (2000) (29)
- Cholinergic contraction is altered in nNOS knockouts. Cooperative modulation of neural bronchoconstriction by nNOS and COX. (1999) (29)
- ADMA: an emerging cardiovascular risk factor (2005) (29)
- Nitric oxide as an antimicrobial agent: does NO always mean NO? (1998) (29)
- Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis. (2007) (28)
- Comment: the asymmetrical dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in the regulation of nitric oxide generation. (2001) (27)
- Role of thromboxane A2 in the vasoconstrictor response to endothelin-1, angiotensin II and 5-hydroxytryptamine in human placental vessels. (1995) (26)
- Nitric oxide in the human cardiovascular system--SKB lecture 1997. (1998) (26)
- Regulation of macrophage nitric oxide synthesis by endothelial cells: a role for NG,NG-dimethylarginine. (1999) (25)
- Intracellular localization of dimethylarginine dimethylaminohydrolase overexpressed in an endothelial cell line. (2000) (24)
- Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates. (2005) (24)
- Association between Kaposi's sarcoma and atherosclerosis: implications for gammaherpesviruses and vascular disease. (2001) (23)
- Vascular Endothelium in Human Physiology and Pathophysiology (2000) (23)
- A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development. (2005) (23)
- Nitric oxide and the control of human vascular tone in health and disease. (1993) (22)
- Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors. (1995) (22)
- Clinical and research (2003) (21)
- Data Sharing as Part of the Normal Scientific Process: A View from the Pharmaceutical Industry (2016) (21)
- The effects of hormone replacement therapy on endothelial function in women with Turner’s syndrome (2002) (20)
- Drugs and the fetus (1996) (20)
- Training in paediatric clinical pharmacology in the UK. (2004) (19)
- Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction. (2010) (19)
- Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia (2000) (19)
- S-nitroso-albumin carries a thiol-labile pool of nitric oxide, which causes venodilation in the rat. (2005) (18)
- Functional effects of econazole on inducible nitric oxide synthase: production of a calmodulin‐dependent enzyme (1996) (17)
- The potassium channel opening drug cromakalim produces arterioselective vasodilation in the upper limbs of healthy volunteers. (1989) (17)
- Developmental Regulation of GTP-CH1 in the Porcine Lung and Its Relationship to Pulmonary Vascular Relaxation (2006) (17)
- Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production (2008) (16)
- Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide. (1996) (16)
- Secure use of individual patient data from clinical trials (2013) (16)
- Dietary nitrate: poison or panacea? (1997) (16)
- Coronavirus: global solutions to prevent a pandemic (2020) (16)
- Identification of microbial dimethylarginine dimethylaminohydrolase enzymes. (1999) (16)
- Local control of human peripheral vascular tone: implications for drug therapy. (1991) (16)
- Control of the human cardiovascular system by nitric oxide. (1996) (15)
- Nobel Lectures: Physiology or Medicine 1996-2000 (2004) (15)
- Nitric oxide: not just a negative inotrope (2001) (14)
- United Kingdom (1997) (14)
- MicroCorrespondence: Identification of microbial dimethylarginine dimethylaminohydrolase enzymes (1999) (14)
- Nitric Oxide in Sepsis: Of Mice and Men (1998) (14)
- Inducible nitric oxide synthase in the cardiovascular system. (1996) (14)
- Enhanced Atherogenesis Is Not an Obligatory Response to Systemic Herpesvirus Infection in the ApoE-Deficient Mouse: Comparison of Murine &ggr;-Herpesvirus-68 and Herpes Simplex Virus-1 (2002) (14)
- ESH/ESC guidelines. (2004) (13)
- ADMA: an emerging cardiovascular risk factor (2005) (13)
- Inhaled nitric oxide—from pollutant to patent (1993) (13)
- Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins. (1997) (13)
- The effect of endothelium-derived nitric oxide on ex vivo whole blood platelet aggregation in man (2004) (13)
- Drug Discovery and Development in the Age of Molecular Medicine (2007) (12)
- Exploring Vascular Nitric Oxide in Health and Disease (1997) (12)
- Developing an open relationship with the drug industry (2005) (12)
- Systemic vascular adaptation to increases in blood volume: the role of the blood-vessel wall. (1996) (11)
- Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease (2020) (11)
- Renoprotective effects of renin-angiotensin-system inhibitors – Authors' reply (2006) (11)
- Are Plantarflexor Muscle Impairments Present Among Individuals with Achilles Tendinopathy and Do They Change with Exercise? A Systematic Review with Meta-analysis (2021) (10)
- Industry-Academic Relationship in a New Era of Drug Discovery. (2016) (10)
- ERYTHROPOIETIN, HAEMOGLOBIN, AND HYPERTENSIVE CRISES (1988) (10)
- Therapeutic Potential of NOS Inhibitors in Septic Shock (2000) (10)
- Endogenous Inhibitors of Nitric Oxide Synthesis:How Important Are They? (1998) (9)
- High dose systemic aspirin protects from inflammatory endothelial dysfunction in humans in vivo. (2001) (9)
- NO in the cardiovascular system. (1999) (9)
- Use of L-arginine and its analogs to study nitric oxide pathway in humans. (1996) (9)
- Biotechnology and new companies arising from academia (2001) (9)
- A post-take ward round. (2005) (9)
- L-NMMA increases arteriolar but not venous tone in humans : the mechanism appears to be independent of sympathetic tone (1991) (8)
- Resolution for sepsis? (2005) (8)
- The interplay between platelet and vessel-wall mediators in coronary artery occlusion. (1989) (7)
- Vascular Nitric Oxide in Health and Disease (2000) (7)
- Epidemiological trends of head and neck cancer survivors in Alberta: Towards improved understanding of the burden of disease. (2018) (7)
- Pharmacogenetics [7] (multiple letters) (2003) (6)
- Endogenous production of nitric oxide synthase inhibitors (2005) (6)
- Drug therapy for coronary heart disease: the Sheffield table (1997) (6)
- Endothelial Function in Hypertension (1997) (6)
- Nitric oxide and blood vessels: Physiological role and clinical implications (1992) (6)
- Regulation of vascular smooth muscle tone in sepsis (1996) (6)
- Identification of two Human Dimethylarginine Dimethylaminohydrolases with Distinct Tissue Distributions and Homology to Arginine Deiminases (2000) (5)
- Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders. (2005) (5)
- Country profile: United Kingdom. (1997) (5)
- ICON 2020—International Scientific Tendinopathy Symposium Consensus: A Systematic Review of Outcome Measures Reported in Clinical Trials of Achilles Tendinopathy (2021) (5)
- Patrick Vallance (1997) (4)
- Sildenafil: desired and undesired effects. (1999) (4)
- Nitric oxide in human hypertension-up, down or unaffected? (1999) (4)
- Releasing the grip of big pharma (2001) (4)
- Oedema after renal artery angioplasty (1993) (4)
- Extracorporeal Shockwave Therapy of Healthy Achilles Tendons Results in a Conditioned Pain Modulation Effect: A Randomised Exploratory Cross-Over Trial (2019) (4)
- Contralateral mechanical hyperalgesia and altered pain modulation in men who have unilateral insertional Achilles tendinopathy: A cross-sectional study. (2021) (4)
- EDRF AND MICROVASCULAR CONSTRICTION AFTER ANGIOPLASTY (1989) (4)
- Nitric oxide and arginine. (1999) (4)
- Book Review Atherothrombosis and Coronary Artery Disease Second edition. Edited by Valentin Fuster, Eric J. Topol, and Elizabeth G. Nabel. 1636 pp., illustrated. Philadelphia, Lippincott Williams & Wilkins, 2005. $149. 0-7817-3583-1 (2005) (3)
- Lifetime risk of developing coronary heart disease (multiple letters) [1] (1999) (3)
- Homocysteine in Health and Disease (2002) (3)
- Hyperhomocysteinaemia and neuropathy in Type 2 diabetes (2001) (3)
- The ADMA/DDAH pathway is a critical regulator of endothelial cell motility (2007) (3)
- Blood vessels and the endothelium (2010) (3)
- Seeking a role for the clinical pharmacologist. (1991) (3)
- Self-reported pain with single leg heel raise or single leg hop offer distinct information as measures of severity in men with midportion and insertional Achilles tendinopathy: An observational cross-sectional study. (2020) (3)
- Cytokine-Mediated Induction of no Synthesis in Humans In Vivo - eNOS Masquerading as iNOS (1997) (2)
- Originality: who is to judge? (1993) (2)
- Maximal isometric force is more strongly associated with Achilles tendinopathy severity than rate of force development and muscle force steadiness (2019) (2)
- The interaction of endothelin with serotonin on umbilical arteries (1990) (2)
- Lifetime risk of developing coronary heart disease (1999) (2)
- Drugs that alter nitric oxide homeostasis: a reply. (1994) (2)
- Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo (2000) (2)
- Nitric Oxide and Hypertension: Physiology and Pathophysiology (1997) (2)
- Biochemical Characterization ofS-Nitrosohemoglobin (1999) (2)
- Use of Nitric Oxide Synthase Inhibitors for the Treatment of Life-Threatening Hypotension in the Septic Syndrome (1992) (2)
- Endogenous inhibitors of nitric oxide synthesis: How important are they? (2006) (2)
- ASPIRIN, INFARCTION, AND PLATELET/VESSEL-WALL INTERACTIONS (1988) (2)
- National Health under new management (1997) (2)
- Dietary nitrate: poison or panacea? [comment] (1997) (2)
- Endogenous inhibitors of nitric oxide synthesis (1997) (1)
- Tetrahydrobiopterin enhances pulmonary arterial relaxation after birth. (2002) (1)
- Global solutions to prevent a pandemic (2020) (1)
- pulmonary circulation of male than female mice Deletion of the eNOS gene has a greater impact on the (2005) (1)
- Separate R&D budget is needed for monitoring effects of new drugs (1998) (1)
- Regulation of GTP Cyclohydrolase I by Estrogen (2002) (1)
- Ischemic preconditioning prevents endothelial injury and immune cell activation during ischemia-reperfusion in humans in vivo. (2000) (1)
- Role of nitric oxide in cardiovascular control in healthy subjects and in patients with renal failure. (1994) (1)
- The revised Approved Instructional Resources score: An improved quality evaluation tool for online educational resources (2021) (1)
- The Effects of Local Intra-Arterial NG-Monomethyl L-Arginine (L-NMMA) in Hypertensive Patients: The Nitric Oxide (NO) Dilator Mechanism Appears Impaired (1991) (1)
- Renal Artery Stenosis: An Unsuspected Cause of Congestive Heart Failure (1993) (1)
- ICON 2020-International Scientific Tendinopathy Symposium Consensus: A Scoping Review of Psychological and Psychosocial Constructs and Outcome Measures Reported in Tendinopathy Clinical Trials. (2022) (1)
- Coronary artery disease—from bench to bedside (2001) (1)
- Animal Experiments and the Doctor (2002) (1)
- Corrigendum to “Effects of aldosterone receptor blockade in patients with mild‐moderate heart failure taking a beta‐blocker” [European Journal of Heart Failure 9/4 (2007) 429–434] (2007) (1)
- Flow-mediated dilatation of human conduit arteries to sustained flow is nitric oxide independent (1999) (1)
- Enhancement of endothelium-dependent vasodilatation by oestradiol 17-beta: Role of the pterin pathway (1999) (1)
- Co-proxamol or paracetamol for acute pain? (1998) (1)
- Patient-Facing Mobile Apps to Support Physiotherapy Care: Protocol for a Systematic Review of Apps Within App Stores (2021) (1)
- An Introduction to Vascular Biology: Nitric oxide (2002) (1)
- Research involving drugs (1994) (0)
- Cardiovascular effects of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) and evidence for ADMA metabolism in humans in vivo (2003) (0)
- Chapter 3 – Discovery and development of drugs (2012) (0)
- A Post-Take Ward Round (2005) (0)
- ADMA/DDAH pathway is a critical regulator of cell motility (2006) (0)
- Endogenous inhibitors of no synthase (1993) (0)
- Structural basis for substrate specificities of cellular deoxyribosenucleoside kinases (2001) (0)
- Patient-facing Mobile Applications to Support Physiotherapy Care: Protocol for a Systematic Review of Apps (Preprint) (0)
- Evidence of systemic and pulmonary endothelial dysfunction in the Dimethylarginine Dimethylaminohydrolase I (DDAH I+/-) heterozygous knockout mouse (2005) (0)
- Book Review: Homocysteine in Health and Disease (2002) (0)
- Characterisation of the DDAH 1 haploinsufficient mouse: A causal role of elevated ADMA in the pathogenesis of cardiovascular disease (2007) (0)
- Circulation and hemodynamics. (1993) (0)
- Basal Nitric Oxide Mediated Vasodilatation in Patients with alcoholic Cirrhosis (1993) (0)
- Amrita Ahluwalia Derived Nitric Oxide − Synthase Constriction of Mesenteric Resistance Arteries in the Absence of Endothelial Nitric Oxide Like Factor Moderates Myogenic − An Endothelium-Derived Hyperpolarizing Factor (2001) (0)
- Science, politics and the pharmaceutical industry: By John Abraham. UCL Press Ltd., London, 1995. 308 pp., £35 (cloth), £12.95 (paper) (1996) (0)
- The Adrian Salter Lecture 2007 (2012) (0)
- Nitric Oxide Axis in Cardiopulmonary Disease (2008) (0)
- The effect of guanidino compounds on nitric oxide synthesis (1993) (0)
- 13 – An ERASMUS scheme for European food engineers (1992) (0)
- Brief Exposure to Endotoxin Produces Prolonged Endothelial Dysfunction in Humans (1996) (0)
- Thepotassium channel opening drugcromakalim produces arterioselective vasodilation intheupperlimbs ofhealthy volunteers (1989) (0)
- Flow-mediated dilatation of human conduit arteries to sustained flow is presented in hypercholesterolaemia (1999) (0)
- Functional effects ofeconazole on inducible nitric oxide synthase: production ofacalmodulin-dependent enzyme (1996) (0)
- Book Review Atherosclerosis and Heart Disease Edited by Andrew Tonkin. 235 pp., illustrated. New York, Martin Dunitz, 2003. $99. 1-84184-123-4 (2004) (0)
- Clinical research: getting the culture right (1997) (0)
- The Complementary Roles of Local and National Ethics Committees (1994) (0)
- Dimethylaminohydrolase New Tricks From an Old Dog : Nitric Oxide-Independent Effects of Dimethylarginine (2013) (0)
- Optimal age for starting lipid lowering treatment - Adjusted data do not justify a lower optimal age - Reply (2000) (0)
- Reactive oxygen species contribute to inflammation-induced endothelial dysfunction (2003) (0)
- Pathophysiological concentrations of ADMA alter human coronary artery endothelial cell gene expression: an insight into the pathophysiological significance of raised plasma ADMA levels (2005) (0)
- NO signalling and endogenous methylarginines (2003) (0)
- Four principles to make evidence synthesis more useful for policy (2018) (0)
- Investigation of vascular mechanisms: bridging the gap between basic research and clinical trials. (1993) (0)
- Effects of Endotoxin on Endothelium-Dependent and -Independent Responses in the Isolated Rat Heart (1998) (0)
- UK chief scientific adviser on swift research visas post-Brexit (2020) (0)
- Endothelial function: 20 years of clinical investigation (2005) (0)
- Assessing calf exercise fidelity among people with Achilles tendinopathy using videos recorded via Zoom®: an observational study. (2023) (0)
- Separate R&D budget is needed for monitoring effects of new drugs. (1998) (0)
- Activation of Human Protease Activated Receptor 2 Dilates Veins and Resistance Vessels In Vivo (2002) (0)
- Determining the neural sites of motor impairment in athletes with patellar tendinopathy (2022) (0)
- Metabolism of Endogenous Nos Inhibitors Lowers Blood Pressure and Regulates Nitric Oxide Synthesis following Hindlimb Ischaemia (2002) (0)
- Modulation of the L-Arginine: Nitric Oxide Pathway in Humans (1994) (0)
- Patrick Vallance: Inquisitive and geeky (2015) (0)
- Age, Herd (2020) (0)
- Vascular events after acute infection or vaccination - Reply (2005) (0)
- Vascular and platelet effects of aspirin: a functional study using arachidonic acid (1995) (0)
- The Accurate Prediction of Cardiovascular Risk. A Ten Year Retrospective Study To Examine Methods of Risk Analysis (2002) (0)
- C-reactive protein alters vascular reactivity by increasing nitric oxide production (2003) (0)
- Opening Plenary (2011) (0)
- The role of renal artery angioplasty in the treatment of congestive heart failure (1994) (0)
- Permeability Changes in the Human Endothelial Cell Line, SGHEC-7, Caused by IL-1β, TNFα and Substance P (1996) (0)
- Taking risks: primary prevention of cardiovascular events. (2001) (0)
- Nitric Oxide–Independent Effects of Dimethylarginine Dimethylaminohydrolase (2006) (0)
- Functional characteristics of insertional and mid-portion achilles tendinopathy (2019) (0)
- MEASUREMENT OF FOREARM BLOOD FLOW. AUTHORS' REPLY (1996) (0)
- Annual Scientific Meeting of the British Hypertension Society 9–11 September 2002, Queens’ College, Cambridge, UK (2002) (0)
- DDAH1 complexed with citrulline (2007) (0)
- Coronavirus: global solutions to prevent a pandemic (2020) (0)
- DDAH FROM PSEUDOMONAS AERUGINOSA. C249S MUTANT COMPLEXED WITH CITRULLINE (2001) (0)
- Plantarflexor neuromuscular performance in Insertional Achilles tendinopathy. (2022) (0)
- DDAH1 complexed with L-257 (2007) (0)
- Exercise adherence in trials of therapeutic exercise interventions for common musculoskeletal conditions: A scoping review. (2023) (0)
- Metabolism ofmethylarginines byhumanvasculature; implications fortheregulation ofnitric oxide synthesis (1994) (0)
- Tetrahydrobiopterin-deficient mouse (HPH-1) displays pulmonary hypertensive phenotype (2004) (0)
- Nephrology Dialysis Transplantation Concentration of dimethyl-L-arginine in the plasma of patients with end-stage renal failure (2005) (0)
- Altered endogenous pain modulation and mechanical pressure hyperalgesia at the unaffected side Achilles tendon insertion in men (2021) (0)
- UK chief scientific adviser on swift research visas post-Brexit (2020) (0)
- Genetic testing (1996) (0)
- Higher Rate of Lymphedema with Inguinal versus Axillary Complete Lymph Node Dissection for Melanoma: A Potential Target for Immediate Lymphatic Reconstruction? (2022) (0)
- Hypothesis of program is flawed - Reply (1999) (0)
- Inhibition of dimethylarginine dimethylaminohydrolase: a novel mechanism for the regulation of blood pressure (1995) (0)
- Age , herd immunity and coronavirus ACG Pensioners Winter (2020) (0)
- Dimethylarginine dimethylaminohydrolase I (DDAH I)heterozygous knockout mice display a cardiovascular phenotype consisting of pulmonary and systemic endothelial dysfunction (2005) (0)
- Endotoxemia increases hepatic dimethylarginine concentrations in vivo: Mechanism and implications for nitric oxide generation (2004) (0)
- 23 Antifungal imidazoles as novel modulators of the L-arginine-nitric oxide pathway (1994) (0)
- The ninety-fifth annual general meeting of the association of physicians of Great Britain and Ireland 2001 (2001) (0)
- Pharmacoeconomic analysis of statin therapy in England; how to save 2 pound billion and improve health (2006) (0)
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