Patrik Brundin
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(Suggest an Edit or Addition)Patrik Brundin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Parkinson disease (2017) (1821)
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation (2008) (1630)
- Diagnosis and management of dementia with Lewy bodies (2017) (1606)
- Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. (1990) (1171)
- The Ubiquitin Proteasome System in Neurodegenerative Diseases Sometimes the Chicken, Sometimes the Egg (2003) (956)
- Pathogenesis of parkinson's disease: dopamine, vesicles and α-synuclein (2002) (746)
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. (2011) (723)
- Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient (1999) (723)
- Prion-like transmission of protein aggregates in neurodegenerative diseases (2010) (697)
- Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease (2002) (619)
- A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease (2008) (559)
- Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. (1989) (511)
- Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (1992) (506)
- Caspase signalling controls microglia activation and neurotoxicity (2011) (504)
- Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. (2002) (465)
- Evidence for long‐term survival and function of dopaminergic grafts in progressive Parkinson's disease (1994) (457)
- Dyskinesias following neural transplantation in Parkinson's disease (2002) (447)
- Transplantation of fetal dopamine neurons in Parkinson's disease: One‐year clinical and neurophysiological observations in two patients with putaminal implants (1992) (367)
- Short‐ and long‐term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease (1997) (360)
- Mechanisms of action of intracerebral neural implants: studies on nigral and striatal grafts to the lesioned striatum (1987) (348)
- Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion‐Like Disorder? (2013) (336)
- Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line* (2002) (332)
- Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice (2005) (328)
- Beyond the brain: widespread pathology in Huntington's disease (2009) (326)
- Research in motion: the enigma of Parkinson's disease pathology spread (2008) (314)
- Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum (1984) (300)
- Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. (2000) (298)
- Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology. (2020) (295)
- Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease (2016) (287)
- Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis (1988) (285)
- Sequential bilateral transplantation in Parkinson's disease: effects of the second graft. (1999) (284)
- Caspase inhibition reduces apoptosis and increases survival of nigral transplants (1999) (282)
- Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival (1985) (274)
- Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts (1990) (269)
- Delayed recovery of movement‐related cortical function in Parkinson's disease after striatal dopaminergic grafts (2000) (267)
- Orexin loss in Huntington's disease. (2005) (265)
- Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. (2002) (264)
- No evidence for new dopaminergic neurons in the adult mammalian substantia nigra. (2004) (263)
- Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports. (2014) (254)
- Acceleration of α-Synuclein Aggregation by Exosomes* (2014) (251)
- Progressive Degeneration of Human Mesencephalic Neuron-Derived Cells Triggered by Dopamine-Dependent Oxidative Stress Is Dependent on the Mixed-Lineage Kinase Pathway (2005) (247)
- Are synucleinopathies prion-like disorders? (2010) (247)
- Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity. (1999) (247)
- Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo (2012) (242)
- Neural transplantation for the treatment of Parkinson's disease (2003) (238)
- Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain (2016) (230)
- Lazaroids improve the survival of grafted rat embryonic dopamine neurons. (1994) (228)
- In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum (1990) (227)
- Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice (2013) (220)
- Cell Survival and Clinical Outcome Following Intrastriatal Transplantation in Parkinson Disease (2001) (218)
- Transplantation of fetal dopamine neurons in Parkinson's disease: PET {18F}6‐L‐fluorodopa studies in two patients with putaminal implants (1992) (218)
- Alpha‐synuclein transfers from neurons to oligodendrocytes (2014) (216)
- Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration. (2001) (214)
- Characterization of Lewy body pathology in 12‐ and 16‐year‐old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease (2010) (210)
- Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6‐hydroxydopamine lesioned adult rats (1992) (207)
- Huntington's disease: a synaptopathy? (2003) (207)
- Prying into the Prion Hypothesis for Parkinson's Disease (2017) (200)
- Neural grafting in a rat model of huntington's disease: Progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting (1985) (198)
- In vivo measurement of spontaneous release and metabolism of dopamine from intrastriatal nigral grafts using intracerebral dialysis (1986) (193)
- The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells (2012) (191)
- Autoregulation of dopamine release and metabolism by intrastriatal nigral grafts as revealed by intracerebral dialysis (1987) (188)
- Survival and function of dissociated rat dopamine neurones grafted at different developmental stages or after being cultured in vitro. (1988) (187)
- Improving the Survival of Grafted Dopaminergic Neurons: A Review over Current Approaches (2000) (186)
- Improving the survival of grafted dopaminergic neurons: a review over current approaches. (2000) (185)
- Triggers, Facilitators, and Aggravators: Redefining Parkinson’s Disease Pathogenesis (2019) (184)
- Synaptic dysfunction in Huntington’s disease: a new perspective (2005) (182)
- The vermiform appendix impacts the risk of developing Parkinson’s disease (2018) (182)
- Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a Link? (2012) (180)
- Weight loss in Huntington disease increases with higher CAG repeat number (2008) (179)
- Critical issues of clinical human embryonic stem cell therapy for brain repair (2008) (177)
- The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases (2016) (176)
- Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient‐Derived Induced Pluripotent Stem Cells (2012) (175)
- Therapeutic approaches to target alpha-synuclein pathology (2017) (169)
- Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease. (2011) (168)
- Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice (2005) (168)
- Recent Advances on the Pathogenesis of Huntington's Disease (1999) (168)
- The use of the R6 transgenic mouse models of Huntington’s disease in attempts to develop novel therapeutic strategies (2005) (167)
- Host afferents into intrastriatal transplants of fetal ventral mesencephalon (1989) (166)
- Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene (2001) (165)
- FETAL DOPAMINE-RICH MESENCEPHALIC GRAFTS IN PARKINSON'S DISEASE (1988) (162)
- Impact of the COVID‐19 Pandemic on Parkinson's Disease and Movement Disorders (2020) (154)
- Paw‐Reaching, Sensorimotor, and Rotational Behavior After Brain Infarction in Rats (1993) (153)
- A deadly spread: cellular mechanisms of α-synuclein transfer (2011) (152)
- Emerging restorative treatments for Parkinson's disease (2008) (151)
- Neural grafting in a rat model of huntington's disease: Striosomal-like organization of striatal grafts as revealed by acetylcholinesterase histochemistry, immunocytochemistry and receptor autoradiography (1987) (151)
- Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases (2019) (146)
- The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis. (2005) (146)
- Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease. (2006) (144)
- Stage-specific modulation of cortical neuronal development by Mmu-miR-134. (2011) (143)
- Neural grafting in Parkinson's disease Problems and possibilities. (2010) (143)
- Neurogenin2 Directs Granule Neuroblast Production and Amplification while NeuroD1 Specifies Neuronal Fate during Hippocampal Neurogenesis (2009) (142)
- Behavioural effects of human fetal dopamine neurons grafted in a rat model of Parkinson's disease (2004) (140)
- Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease (1995) (138)
- Overexpression of heat shock protein 70 in R6/2 Huntington’s disease mice has only modest effects on disease progression (2003) (138)
- Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term (2017) (135)
- Increased metabolism in the R6/2 mouse model of Huntington’s disease (2008) (134)
- Cholinergic neuronal defect without cell loss in Huntington's disease. (2006) (133)
- Survival, growth and function of dopaminergic neurons grafted to the brain. (1987) (131)
- An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation (2016) (131)
- Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. (1991) (128)
- Biomarker‐driven phenotyping in Parkinson's disease: A translational missing link in disease‐modifying clinical trials (2017) (127)
- Targeted Therapies for Parkinson's Disease: From Genetics to the Clinic (2018) (127)
- Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease (2016) (126)
- Precision medicine for disease modification in Parkinson disease (2017) (125)
- Endothelial Proliferation and Increased Blood–Brain Barrier Permeability in the Basal Ganglia in a Rat Model of 3,4-Dihydroxyphenyl-l-Alanine-Induced Dyskinesia (2006) (123)
- Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: immunological aspects, spontaneous and drug-induced behaviour, and dopamine release (1988) (121)
- The concept of alpha-synuclein as a prion-like protein: ten years after (2018) (121)
- Amelioration of spatial memory impairment by intrahippocampal grafts of mixed septal and raphe tissue in rats with combined cholinergic and serotonergic denervation of the forebrain (1990) (116)
- Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. (2010) (115)
- The Importance of Graft Placement and Task Complexity for Transplant‐Induced Recovery of Simple and Complex Sensorimotor Deficits in Dopamine Denervated Rats (1990) (109)
- Can Parkinson's disease pathology be propagated from one neuron to another? (2012) (106)
- Reduced neurogenesis in the rat hippocampus following high fructose consumption (2011) (106)
- Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells (2013) (106)
- Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function, and Cell Survival (2010) (105)
- Comparison of growth and reinnervation properties of cholinergic neurons from different brain regions grafted to the hippocampus (1988) (103)
- α‐Synuclein: The Long Distance Runner (2013) (102)
- Signs of degeneration in 12-22-year old grafts of mesencephalic dopamine neurons in patients with Parkinson's disease. (2011) (100)
- Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment (2009) (99)
- Evidence for Dysfunction of the Nigrostriatal Pathway in the R6/1 Line of Transgenic Huntington's Disease Mice (2002) (96)
- Antioxidant treatment protects striatal neurons against excitotoxic insults (1996) (96)
- Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis (2009) (95)
- Patterns of Cell Death and Dopaminergic Neuron Survival in Intrastriatal Nigral Grafts (1999) (95)
- Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice (2001) (94)
- Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons (2000) (94)
- Gut feelings about smoking and coffee in Parkinson's disease (2014) (94)
- Alpha‐synuclein propagation: New insights from animal models (2016) (93)
- Membrane interaction of α-synuclein in different aggregation states. (2011) (93)
- Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease (2019) (91)
- Effects of α-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionate (1996) (90)
- The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat (2006) (89)
- Increased thirst and drinking in Huntington's disease and the R6/2 mouse (2008) (89)
- Additive Effects of Caspase Inhibitor and Lazaroid on the Survival of Transplanted Rat and Human Embryonic Dopamine Neurons (2000) (88)
- Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy. (1987) (87)
- Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: a role for protease activation (2003) (86)
- Effects on Differentiation of Embryonic Ventral Midbrain Progenitors by Lmx1a, Msx1, Ngn2, and Pitx3 (2008) (86)
- The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy. (2008) (86)
- From bench to bed: the potential of stem cells for the treatment of Parkinson’s disease (2007) (86)
- Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro. (1995) (86)
- Loss of SNAP‐25 and rabphilin 3a in sensory‐motor cortex in Huntington’s disease (2007) (84)
- Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells. (1986) (82)
- Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats (2004) (82)
- Is COVID-19 a Perfect Storm for Parkinson’s Disease? (2020) (82)
- Effect of Prior Dopamine Denervation on Survival and Fiber Outgrowth from Intrastriatal Fetal Mesencephalic Grafts (1990) (82)
- Immunotherapy in Parkinson’s Disease: Micromanaging Alpha-Synuclein Aggregation (2015) (81)
- Review: The future of cell therapies and brain repair: Parkinson's disease leads the way (2014) (80)
- Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases. (2006) (80)
- Sequential intrastriatal grafting of allogeneic embryonic dopamine-rich neuronal tissue in adult rats: Will the second graft be rejected? (1993) (79)
- Dissecting the potential molecular mechanisms underlying alpha-synuclein cell-to-cell transfer in Parkinson's disease. (2009) (79)
- Systemic administration of neuregulin‐1β1 protects dopaminergic neurons in a mouse model of Parkinson’s disease (2011) (79)
- Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease (2015) (78)
- trans‐Resveratrol Protects Embryonic Mesencephalic Cells from tert‐Butyl Hydroperoxide (2000) (77)
- Human embryonic dopamine neurons xenografted to the rat: effects of cryopreservation and varying regional source of donor cells on transplant survival, morphology and function (1994) (77)
- Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry (2004) (76)
- Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics. (2013) (75)
- DARPP-32-rich zones in grafts of lateral ganglionic eminence govern the extent of functional recovery in skilled paw reaching in an animal model of Huntington's disease (1996) (75)
- Gastrointestinal dysfunction contributes to weight loss in Huntington's disease mice (2011) (75)
- Sorting out release, uptake and processing of alpha‐synuclein during prion‐like spread of pathology (2016) (75)
- Brain injury activates microglia that induce neural stem cell proliferation ex vivo and promote differentiation of neurosphere-derived cells into neurons and oligodendrocytes (2010) (75)
- Disease modification and biomarker development in Parkinson disease (2020) (74)
- The effect of α‐synuclein knockdown on MPP+ toxicity in models of human neurons (2008) (74)
- A cell culture model for monitoring α-synuclein cell-to-cell transfer (2015) (74)
- Synaptic connections formed by grafts of different types of cholinergic neurons in the host hippocampus (1990) (72)
- Intracerebral Grafting of Dopamine Neurons (1987) (71)
- Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice (2004) (70)
- Practical aspects of the use of human fetal brain tissue for intracerebral grafting. (1990) (70)
- Nitric Oxide Stimulates the Proliferation of Neural Stem Cells Bypassing the Epidermal Growth Factor Receptor (2010) (70)
- GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2. (2010) (70)
- Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease (2005) (69)
- Stem cell‐based therapy for Parkinson's disease (2005) (69)
- Functional integration of cortical grafts placed in brain infarcts of rats (1993) (69)
- Sequential Intracerebral Transplantation of Allogeneic and Syngeneic Fetal Dopamine-Rich Neuronal Tissue in Adult Rats: Will the First Graft be Rejected? (1993) (68)
- Intrastriatal Ventral Mesencephalic Xenografts of Porcine Tissue in Rats: Immune Responses and Functional Effects (2000) (67)
- Differential Trophic Effects of Basic Fibroblast Growth Factor, Insulin-like Growth Factor-1, and Neurotrophin-3 on Striatal Neurons in Culture (1996) (66)
- Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease (2020) (66)
- The role of Galectin-3 in α-synuclein-induced microglial activation (2014) (66)
- Enriched Environment Attenuates Cell Genesis in Subventricular Zone After Focal Ischemia in Mice and Decreases Migration of Newborn Cells to the Striatum (2006) (65)
- Partial resistance to malonate‐induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length (2001) (65)
- Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons (2004) (65)
- Survival of intracerebrally grafted rat dopamine neurons previously cultured in vitro (1985) (64)
- Failure of Transdifferentiation of Adult Hematopoietic Stem Cells into Neurons (2006) (64)
- Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016? (2016) (63)
- Grafts of fetal locus coeruleus neurons in rat amygdala-piriform cortex suppress seizure development in hippocampal kindling (1989) (62)
- Cell transplantation in Parkinson's disease: problems and perspectives. (2010) (62)
- The rotating 6-hydroxydopamine-lesioned mouse as a model for assessing functional effects of neuronal grafting (1986) (61)
- Middle cerebral artery occlusion in the hypertensive and normotensive rat: a study of histopathology and behaviour. (1988) (60)
- What’s to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease? (2013) (60)
- The lazaroid U-83836E improves the survival of rat embryonic mesencephalic tissue stored at 4°C and subsequently used for cultures or intracerebral transplantation (1996) (60)
- Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion‐like behaviour of alpha‐synuclein (2016) (59)
- α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb (2019) (58)
- Fetal neocortical grafts implanted in adult hypertensive rats with cortical infarcts following a middle cerebral artery occlusion: Ingrowth of afferent fibers from the host brain (1992) (57)
- Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis (2015) (57)
- Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation (2007) (57)
- How strong is the evidence that Parkinson's disease is a prion disorder? (2016) (56)
- Prion-like propagation of pathology in Parkinson disease. (2018) (52)
- Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes (2005) (52)
- Neurogenesis in the R6/2 mouse model of Huntington's disease is impaired at the level of NeuroD1 (2011) (52)
- Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture (2004) (51)
- Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier (2004) (51)
- Calpain activation is involved in early caspase‐independent neurodegeneration in the hippocampus following status epilepticus (2008) (51)
- Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease (2021) (51)
- A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP (2013) (51)
- Lazaroids improve the survival of cultured rat embryonic mesencephalic neurones. (1994) (51)
- Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion. (2009) (51)
- Maintenance of Susceptibility to Neurodegeneration Following Intrastriatal Injections of Quinolinic Acid in a New Transgenic Mouse Model of Huntington's Disease (2002) (51)
- Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation (2019) (50)
- Can infections trigger alpha-synucleinopathies? (2019) (50)
- Lewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another? (2009) (50)
- Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain (2006) (50)
- Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology (2016) (49)
- The executioners sing a new song: killer caspases activate microglia (2011) (49)
- Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats (2009) (49)
- Nonsteroidal selective androgen receptor modulators and selective estrogen receptor β agonists moderate cognitive deficits and amyloid-β levels in a mouse model of Alzheimer's disease. (2013) (49)
- Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy. (2012) (49)
- Survival of expanded dopaminergic precursors is critical for clinical trials (1998) (48)
- Decreased VIP and VPAC2 receptor expression in the biological clock of the R6/2 Huntington's disease mouse (2007) (48)
- Neural transplantation in Parkinson's disease: the Swedish experience. (1990) (48)
- Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats (2004) (48)
- FK506 and Cyclosporin A Enhance the Survival of Cultured and Grafted Rat Embryonic Dopamine Neurons (2000) (47)
- Selective sub-dissection of the striatal primordium for cultures affects the yield of DARPP-32-containing neurones. (1994) (47)
- Phenotypic development of the human embryonic striatal primordium: A study of cultured and grafted neurons from the lateral and medial ganglionic eminences (1996) (47)
- Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6‐hydroxydopamine (2001) (47)
- Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease (2020) (47)
- Differential effects of Bcl‐2 overexpression on fibre outgrowth and survival of embryonic dopaminergic neurons in intracerebral transplants (1999) (46)
- Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration (2018) (46)
- Serotonin neurons grafted to the adult rat hippocampus. I. Time course of growth as studied by immunohistochemistry and biochemistry (1988) (45)
- GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop (2020) (45)
- Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles. (2018) (45)
- Tirilazad Mesylate Improves Survival of Rat and Human Embryonic Mesencephalic Neuronsin Vitro (1997) (43)
- Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease (2008) (43)
- Immune reactions following systemic immunization prior or subsequent to intrastriatal transplantation of allogeneic mesencephalic tissue in adult rats (1995) (42)
- Alpha-Synuclein to the Rescue: Immune Cell Recruitment by Alpha-Synuclein during Gastrointestinal Infection (2017) (41)
- Flunarizine improves the survival of grafted dopaminergic neurons (1999) (41)
- Transplanted dopaminergic neurons: More or less? (2001) (41)
- Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room (2019) (41)
- Quinolinic acid‐induced inflammation in the striatum does not impair the survival of neural allografts in the rat (1998) (40)
- Stem cell therapy for Parkinson’s disease: where do we stand? (2004) (40)
- A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein (2018) (39)
- Lazaroid Treatment Prevents Death of Cultured Rat Embryonic Mesencephalic Neurons Following Glutathione Depletion (1996) (39)
- Is Axonal Degeneration a Key Early Event in Parkinson's Disease? (2016) (39)
- Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction (2005) (39)
- Linked Clinical Trials – The Development of New Clinical Learning Studies in Parkinson’s Disease Using Screening of Multiple Prospective New Treatments (2013) (39)
- Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease. (2000) (38)
- Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease (2009) (38)
- Rat fetal brain tissue grafts survive and innervate host brain following five day pregraft tissue storage (1985) (37)
- Effects of anaesthetics and lazaroid U-83836E on survival of transplanted rat dopaminergic neurones 1 Published on the World Wide Web on 4 February 1999. 1 (1999) (37)
- Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor (2005) (37)
- Cerebrospinal fluid levels of orexin‐A are not a clinically useful biomarker for Huntington disease (2006) (36)
- Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line—Studies in vitro and after intracerebral grafting in vivo (2007) (36)
- Survival of Fetal Neocortical Grafts Implanted in Brain Infarcts of Adult Rats: The Influence of Postlesion Time and Age of Donor Tissue (1994) (36)
- Rasagiline Ameliorates Olfactory Deficits in an Alpha-Synuclein Mouse Model of Parkinson's Disease (2013) (36)
- Paucity of P-zones in striatal grafts prohibit commencement of clinical trials in Huntington's disease (1996) (36)
- Excitotoxicity Plays a Role in the Death of Tyrosine Hydroxylase- Immunopositive Nigral Neurons Cultured in Serum-Free Medium (1999) (35)
- Intracerebral grafting of embryonic neural cells into the adult host brain: an overview of the cell suspension method and its application. (1983) (35)
- Developmental Features of Human Striatal Tissue Transplanted in a Rat Model of Huntington's Disease (1997) (34)
- Host regulation of noradrenaline release from grafts of seizure-suppressant locus coeruleus neurons (1991) (34)
- Serotonin neurons grafted to the adult rat hippocampus. II. 5-HT release as studied by intracerebral microdialysis (1989) (34)
- Proteolysis of NR2B by calpain in the hippocampus of epileptic rats (2005) (34)
- Stem cells: hype or hope? (2002) (32)
- Neocortical Grafts Placed in the Infarcted Brain of Adult Rats: Few or No Efferent Fibers Grow from Transplant to Host (1995) (32)
- GDNF treatment in Parkinson's disease: time for controlled clinical trials? (2002) (32)
- Fibroblast Growth Factor-20 Increases the Yield of Midbrain Dopaminergic Neurons Derived from Human Embryonic Stem Cells (2007) (32)
- Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein (2017) (32)
- Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease (2007) (32)
- Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase (1997) (32)
- Mind the gut: secretion of α‐synuclein by enteric neurons (2013) (32)
- Characterisation of cell damage and death in embryonic mesencephalic tissue: a study on ultrastructure, vital stains and protease activity (2002) (31)
- Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing. (1990) (31)
- Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease (2018) (31)
- An Efficient Procedure for Removal and Inactivation of Alpha-Synuclein Assemblies from Laboratory Materials (2015) (31)
- Preparation and Intracerebral Grafting of Dissociated Fetal Brain Tissue in Rats (1991) (31)
- Nilotinib – Differentiating the Hope from the Hype (2016) (31)
- Effects of alpha-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid. (1997) (30)
- Mutant huntingtin can paradoxically protect neurons from death (2008) (29)
- Exendin-4 Treatment Improves LPS-Induced Depressive-Like Behavior Without Affecting Pro-Inflammatory Cytokines (2017) (29)
- Methylprednisolone prevents rejection of intrastriatal grafts of xenogeneic embryonic neural tissue in adult rats (1996) (29)
- Is Exenatide a Treatment for Parkinson's Disease? (2017) (29)
- Increased survival of embryonic nigral neurons when grafted to hypothermic rats (2000) (29)
- Vascularization of fetal neocortical grafts implanted in brain infarcts in spontaneously hypertensive rats (1992) (28)
- Cocaine‐ and amphetamine‐regulated transcript is increased in Huntington disease (2007) (28)
- Restorative cell therapy for Parkinson's disease: a quest for the perfect cell. (2007) (28)
- The neurobiology of cell transplantation in Parkinson's disease (2001) (27)
- NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease. (2013) (27)
- Addition of allogeneic spleen cells causes rejection of intrastriatal embryonic mesencephalic allografts in the rat (1997) (26)
- Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake (1989) (26)
- Propagation of host disease to grafted neurons: Accumulating evidence (2009) (26)
- A simple method for large‐scale generation of dopamine neurons from human embryonic stem cells (2010) (26)
- New Frontiers in Parkinson's Disease: From Genetics to the Clinic (2018) (26)
- Neuronal replacement by intracerebral neural implants in animal models of neurodegenerative disease. (1988) (26)
- Can human fetal dopamine neuron grafts provide a therapy for Parkinson's disease? (1988) (25)
- Impact of the COVID‐19 Pandemic on Parkinson's Disease and Movement Disorders (2020) (25)
- Immunological aspects of neural grafting in the mammalian central nervous system. (1988) (25)
- Seizure suppression in kindling epilepsy by intrahippocampal locus coeruleus grafts: evidence for an alpha-2-adrenoreceptor mediated mechanism (2004) (24)
- Dopamine neurons grafted unilaterally to the nucleus accumbens affect drug-induced circling and locomotion (2004) (24)
- Important Aspects of Surgical Methodology for Transplantation in Parkinson's Disease (2006) (24)
- Oxidative stress in neurodegenerative disease: causation or association? (2017) (24)
- "NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells (2007) (23)
- Platelet-derived growth factor exerts trophic effects on rat striatal DARPP-32-containing neurons in culture (1994) (23)
- Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia. (2004) (22)
- Islet β-cell area and hormone expression are unaltered in Huntington’s disease (2008) (22)
- Caspase Inhibition Increases Embryonic Striatal Graft Survival (2000) (22)
- Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting (2018) (22)
- The role of Galectin-3 in α-synuclein-induced microglial activation (2014) (22)
- Deficits in olfactory sensitivity in a mouse model of Parkinson’s disease revealed by plethysmography of odor-evoked sniffing (2020) (22)
- Comparison between survival of lazaroid-treated embryonic nigral neurons in cell suspensions, cultures and transplants (2002) (22)
- MK‐801 does not enhance dopaminergic cell survival in embryonic nigral grafts (1998) (22)
- Is the Enzyme ACMSD a Novel Therapeutic Target in Parkinson’s Disease? (2017) (22)
- Basic science breaks through: New therapeutic advances in Parkinson's disease (2015) (22)
- Growth Factors and Feeder Cells Promote Differentiation of Human Embryonic Stem Cells into Dopaminergic Neurons: A Novel Role for Fibroblast Growth Factor-20 (2008) (22)
- Rat Intrastriatal Neural Allografts Challenged with Skin Allografts at Different Time Points (1997) (21)
- Effects of Ciliary Neurotrophic Factor on Excitotoxicity and Calcium-Ionophore A23187-Induced Cell Death in Cultured Embryonic Striatal Neurons (1999) (21)
- Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease (2014) (21)
- Parkinson Matters (2018) (21)
- Formation of synaptic graft-host connections by noradrenergic locus coeruleus neurons transplanted into the adult rat hippocampus (1990) (21)
- Precision medicine in Parkinson’s disease patients with LRRK2 and GBA risk variants – Let’s get even more personal (2020) (20)
- Journal of Parkinson's disease. (2011) (20)
- Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells (2010) (20)
- Chapter 16 Neurodegeneration and glutamate induced oxidative stress (1998) (20)
- Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson’s Disease? (2020) (19)
- Effects of Antioxidant Pretreatment on the Survival of Embryonic Dopaminergic Neurons In Vitro and following Grafting in an Animal Model of Parkinson's Disease (2002) (19)
- Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries (2009) (19)
- Treatment with the spin-trap agent α-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons (1998) (19)
- Combining Neuroprotective Treatment of Embryonic Nigral Donor Tissue with Mild Hypothermia of the Graft Recipient (2005) (19)
- Recent Advances in the Development of Stem‐Cell‐Derived Dopaminergic Neuronal Transplant Therapies for Parkinson's Disease (2021) (18)
- Neuregulin-1 receptor tyrosine kinase ErbB4 is upregulated in midbrain dopaminergic neurons in Parkinson disease (2012) (18)
- MEASURING THE ACOUSTOPHORETIC CONTRAST FACTOR OF LIVING CELLS IN MICROCHANNELS (2010) (18)
- Intracerebral grafting of fetal noradrenergic locus coeruleus neurons: evidence for seizure suppression in the kindling model of epilepsy. (1988) (17)
- Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes (2005) (17)
- Grafting of Nigral Tissue Hibernated with Tirilazad Mesylate and Glial Cell Line-Derived Neurotrophic Factor (2000) (17)
- Striatal Neural Transplants in the Ibotenic Acid‐lesioned Rat Neostriatum (1987) (17)
- Intracellular Nogo-A facilitates initiation of neurite formation in mouse midbrain neurons in vitro (2014) (17)
- Effects of hibernation or cryopreservation on the survival and integration of striatal grafts placed in the ibotenate-lesioned rat caudate-putamen. (1995) (16)
- Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft (2004) (16)
- COVID-19 Vaccination for Persons with Parkinson’s Disease: Light at the End of the Tunnel? (2021) (16)
- Addition of lateral ganglionic eminence to rat mesencephalic grafts affects fiber outgrowth but does not enhance function. (1997) (16)
- Large stem cell grafts could lead to erroneous interpretations of behavioral results? (2007) (16)
- Survival and immunogenicity of dissociated allogeneic fetal neural dopamine-rich grafts when implanted into the brains of adult mice (2004) (15)
- Upregulation of α-synuclein following immune activation: Possible trigger of Parkinson's disease (2022) (15)
- Restorative Therapies in Parkinson's Disease (2006) (15)
- Behavioural effects of genetically engineered cells releasing dopa and dopamine after intracerebral grafting in a rat model of Parkinson's disease. (1991) (15)
- The Linked Clinical Trials initiative (LCT) for Parkinson's disease (2018) (15)
- Human fetal basal forebrain neurons grafted to the denervated rat hippocampus produce an organotypic cholinergic reinnervation pattern (1988) (15)
- Fetal neocortical grafts placed in brain infarcts do not improve paw-reaching deficits in adult spontaneously hypertensive rats. (1996) (14)
- Huntington's disease: the mystery unfolds? (2002) (13)
- Late onset vascular dysfunction in the R6/1 model of Huntington's disease. (2013) (13)
- Transplanted allogeneic fetal dopamine neurons survive and improve motor function in idiopathic Parkinson's disease. (1991) (13)
- Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry (2004) (13)
- A new approach to disease-modifying drug trials in Parkinson's disease. (2013) (12)
- Locus coeruleus grafts in hippocampal kindling epilepsy: noradrenaline release, receptor specificity and influence on seizure development. (1990) (12)
- Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism. (1993) (12)
- T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils (2020) (12)
- Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents (2003) (12)
- Mitomycin‐C treatment during differentiation of induced pluripotent stem cell‐derived dopamine neurons reduces proliferation without compromising survival or function in vivo (2020) (11)
- Editorial: Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases (2020) (11)
- Neurodegeneration and glutamate induced oxidative stress. (1998) (11)
- Parkinson disease: Laying the foundations for disease-modifying therapies in PD (2015) (11)
- Expression of Platelet-Derived Growth Factor in and around Intrastriatal Embryonic Mesencephalic Grafts (1993) (11)
- Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms (2022) (11)
- Drug Repurposing for Parkinson’s Disease: The International Linked Clinical Trials experience (2021) (10)
- Transplantation in Parkinson's disease: The future looks bright. (2006) (10)
- Cancer enzyme affects Parkinson's disease (2018) (10)
- Experimental colitis drives enteric alpha-synuclein accumulation and Parkinson-like brain pathology (2018) (10)
- Decreased Risk of Parkinson’s Disease After Rheumatoid Arthritis Diagnosis: A Nested Case-Control Study with Matched Cases and Controls (2021) (10)
- Neuronal death in nigral grafts in the absence of poly (ADP-ribose) polymerase activation. (1999) (10)
- Intracerebral Transplantation of Dopamine Neurons: Understanding the Functional Role of the Mesolimbocortical Dopamine System and Developing a Therapy for Parkinson's Disease a (1988) (10)
- Perturbation of in vivo neural activity following α-Synuclein seeding in the olfactory bulb (2020) (10)
- Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology (2020) (9)
- Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson’s disease (2022) (9)
- Pre‐existing immunity to adeno‐associated virus (AAV)2 limits transgene expression following intracerebral AAV2‐based gene delivery in a 6‐hydroxydopamine model of Parkinson's disease (2014) (9)
- Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy (2005) (9)
- Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy (2019) (9)
- The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1 (2015) (9)
- Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival (1999) (9)
- CuZn superoxide dismutase transgenic retinal transplants (1999) (8)
- An extended release GLP-1 analogue increases α-synuclein accumulation in a mouse model of prodromal Parkinson's disease (2021) (8)
- Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson’s Disease (2016) (8)
- Could miRNA expression changes be a reliable clinical biomarker for Parkinson’s disease? (2013) (8)
- Neuronal transplantation in rat models of Parkinson's and Huntington's diseases (1993) (8)
- Solving the conundrum of insoluble protein aggregates (2017) (7)
- Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality (2021) (7)
- Ultrastructural Characterization of Dissociated Embryonic Ventral Mesencephalic Tissue Treated with Neuroprotectants (2003) (7)
- Heterozygous GBA D409V and ATP13a2 mutations do not exacerbate pathological α-synuclein spread in the prodromal preformed fibrils model in young mice (2021) (7)
- Compensation of Lesion-Induced Changes in Cerebral Metabolism and Behaviour by Striatal Neural Implants in a Rat Model of Huntington’s Disease (1985) (7)
- Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E (2006) (7)
- Effects of Hibernation or Cryopreservation on the Survival and Integration of Striatal Grafts Placed in the Ibotenate-Lesioned Rat Caudate-Putamen (1995) (7)
- Silencing synuclein at the synapse with PLK2 (2013) (6)
- Faculty Opinions recommendation of Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. (2010) (6)
- In reply: fetal brain grafts and Parkinson's disease. (1990) (6)
- NILOTINIB IN PATIENTS WITH ADVANCED PARKINSONS DISEASE: A RANDOMIZED PHASE 2A STUDY (NILO-PD) (2020) (6)
- Intracerebral Neuronal Grafting in Experimental Animal Models of Age‐related Motor Dysfunction a (1988) (6)
- Can α-synuclein be targeted in novel therapies for Parkinson’s disease? (2011) (6)
- Article Commentary: Cell Transplantation and Neuroscience (1999) (5)
- Neuroprotective Strategies in Neural Grafting (2000) (5)
- The Times They Are a-Changin’: Parkinson’s Disease 20 Years from Now (2018) (5)
- Novel approaches to counter protein aggregation pathology in Parkinson's disease. (2020) (5)
- BRIEF COMMUNICATION Maintenance of Susceptibility to Neurodegeneration Following Intrastriatal Injections of Quinolinic Acid in a New Transgenic Mouse Model of Huntington's Disease (2002) (5)
- GRAFT SURVIVAL. AUTHORS' REPLY (1999) (5)
- Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson’s disease models (2021) (5)
- How I examine my patient: the art of neurological examination for Parkinson's disease. (2014) (5)
- Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits (2020) (5)
- Pretreatment with MK-801 or the Lazaroid U-83836E does not Enhance Striatal Graft Survival (2000) (5)
- Brief Communication Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease (2007) (5)
- Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a Link? (2012) (4)
- Alpha-synuclein supports interferon stimulated gene expression in neurons (2020) (4)
- Is exenatide the next big thing in Parkinson's disease? (2014) (4)
- Sequential bilateral transplantation in Parkinson's (1999) (4)
- On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease (2006) (4)
- Widespread, specific and efficient transgene expression in oligodendrocytes after intracerebral and intracerebroventricular delivery of viral vectors in rodent brain. (2021) (4)
- Grafts of Embryonic Dopamine Neurons in Rodent Models of Parkinson's Disease (1999) (4)
- The roles of connectivity and neuronal phenotype in determining the pattern of α-synuclein pathology in Parkinson's disease (2022) (4)
- Fetal Dopamine Neurons Implanted Unilaterally into the Nucleus Accumbens Drive Amphetamine‐induced Locomotion and Circling (1987) (4)
- Grafting of nigral tissue hibernated with tirilazad mesylate and glial cell line-derived neurotrophic factor. (2000) (4)
- Graft survival. (1999) (4)
- Prion-Like Propagation in Neurodegenerative Diseases (2018) (4)
- CHOLECYSTOKININ CONTENT IN THE BASAL GANGLIA IN HUNTINGTONS-DISEASE - THE EXPRESSION OF CHOLECYSTOKININ IMMUNOREACTIVITY IN STRIATAL GRAFTS TO IBOTENIC ACID-LESIONED RAT STRIATUM (1985) (4)
- disrupts vesicular transport and insulin secretion (2009) (4)
- Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient‐Derived Induced Pluripotent Stem Cells (2012) (4)
- Gut microbiome dysbiosis is associated with elevated toxic bile acids in Parkinson’s disease (2020) (3)
- Fire prevention in the Parkinson’s disease brain (2018) (3)
- Uses of Neuronal Transplantation in Models of Neurodegenerative Diseases (1986) (3)
- 24 Adult Neurogenesis in Neurodegenerative Diseases (2008) (3)
- Cholecystokinin Content in the Basal Ganglia in Huntington's Disease (1985) (3)
- Axonal transport dysfunction in neurodegenerative diseases: the “holy grail” for developing disease modifying therapies? (2017) (3)
- The Origin , Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD 1 (2015) (3)
- Funding embryonic stem-cell research: will commerce counteract collaboration? (2002) (3)
- Grafting dopamine neurons in Parkinson's disease: do stem cells have a role in the future? (2003) (2)
- Interactive report C omparison between survival of lazaroid-treated embryonic nigral neurons in cell suspensions, cultures and transplants (2002) (2)
- Digesting recent findings: gut alpha-synuclein, microbiome changes in Parkinson’s disease (2021) (2)
- Research report Treatment with the spin-trap agent a-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons (1998) (2)
- Genetically engineered stem cell‐derived neurons can be rendered resistant to alpha‐synuclein aggregate pathology (2019) (2)
- Methylated Cytochrome P450 and the Solute Carrier Family of Genes Correlate With Perturbations in Bile Acid Metabolism in Parkinson’s Disease (2022) (2)
- Butyrate and related epigenetic changes link Parkinson's disease to inflammatory bowel disease and depressive symptoms (2021) (2)
- Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis (2021) (2)
- Neuregulin-1 receptor ErbB4 is upregulated in human midbrain dopaminergic neurons in Parkinson disease and in vitro Parkinson-models (2013) (2)
- Low plasma serotonin linked to higher nigral iron in Parkinson’s disease (2021) (2)
- Mechanisms for cell‐to‐cell propagation no longer lag behind (2016) (2)
- Precision medicine in Parkinson’s disease patients with LRRK2 and GBA risk variants – Let’s get even more personal (2020) (2)
- [Huntington disease--yet another mad protein?]. (2001) (2)
- Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease (2022) (2)
- The importance of graft size in the development of graft-induced dyskinesia [Abstract] (2005) (2)
- Title: Alpha-synuclein expression supports interferon stimulated gene expression in neurons (2020) (2)
- [Promising new results with transplantation of nerve cells to the brain in Parkinson disease]. (1990) (1)
- BRAIN INJURY ACTIVATES MICROGLIA THAT INDUCE NEURAL STEM CELL PROLIFERATION AND PROMOTE DIFFERENTIATION OF NEUROSPHERE-DERIVED CELLS INTO NEURONS AND TO OLIGODENDROCYTES (2009) (1)
- Parkinson’s Disease: We Care! (2020) (1)
- Moving Forward in Times of Crisis. (2020) (1)
- P3-377: A novel pathogenic pathway of immune activation detectable before cinical onset in Huntington's disease (2008) (1)
- Future Cell‐ and Gene‐Based Therapies for Parkinson's Disease (2008) (1)
- Disease Primers PARKINSON DISEASE (2017) (1)
- Addition of Lateral Ganglionic Eminence to Rat Mesencephalic Grafts Affects Fiber Outgrowth but Does not Enhance Function (1997) (1)
- The Dawning of a Brighter Future: Celebrating 10 Years of Journal of Parkinson's Disease. (2021) (1)
- Prion-like mechanisms in Parkinson Disease (2019) (1)
- Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala (2022) (1)
- Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring (2022) (1)
- Editorial: Pathogenic templating proteins in Neurodegenerative Disease (2018) (1)
- [Free radicals and ailing proteins--the culprits behind Parkinson disease?]. (2003) (1)
- Enhanced survival of transplanted dopaminergic neurons overexpressing CuZn-superoxide dismutase in a rat model of Parkinson's disease (1996) (1)
- The Future of Parkinson Care and Research is Here. (2020) (1)
- Lots of Movement in Gut and Parkinson’s Research (2019) (1)
- Alterations in odor hedonics in the 5XFAD Alzheimer's disease mouse model and the influence of sex. (2020) (1)
- Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease (2014) (1)
- Long-term Locomotor and Cognitive Deficits in Rats with 6-OHDA Lesions of the VTA: A Model for Transplantation Studies (1986) (1)
- Weight loss in Huntington's disease is related to the number of CAG repeats (2008) (1)
- Protein-protein interactions in poly-Q disease model (2008) (1)
- 840. Developing a Rodent Model of Depression and Neurodegenerative Disease by Targeting ACMSD, a Key Enzyme in the Kynurenine Pathway (2017) (1)
- Repairing the Parkinson Brain. (2021) (1)
- Adult neurogenesis in neurodegenerative diseases (2007) (1)
- α-Synuclein perturbs in vivo neural activity following seeding in the olfactory bulb (2020) (1)
- Stem Cells and Huntington’s Disease (2005) (1)
- Using Technology to Reshape Clinical Care and Research in Parkinson's disease. (2021) (1)
- Editorial Board (2007) (0)
- Fire prevention in the Parkinson’s disease brain (2018) (0)
- Preliminary Clinical Experience with Neural Transplantation: Two Case Reports (1998) (0)
- Urinary tract infections trigger synucleinopathy via the innate immune response (2023) (0)
- Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity (2023) (0)
- Digesting recent findings: gut alpha-synuclein, microbiome changes in Parkinson’s disease (Trends in Endocrinology & Metabolism 33, 147–157; 2022) (2022) (0)
- Prion-like propagation of Parkinson's disease (2014) (0)
- Very long-term clinical outcome of fetal cell transplantation for Parkinson's disease (2014) (0)
- Journal of Parkinson's Disease--an excellent first year and a new sister. (2012) (0)
- P167 Neuregulin-1β1 protects dopaminergic neurons in models of Parkinson’s disease (2011) (0)
- Precision medicine in Parkinson ’ s disease patients with 1 LRRK 2 and GBA risk variants – Let ’ s get even more 2 personal 3 4 (2020) (0)
- Editorial: Targeting α-Synuclein in Parkinson's Disease and Multiple System Atrophy (2022) (0)
- A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model (2022) (0)
- Improved Survival of Grafted Dopamine Neurons by Calcineurin Inhibitors (2003) (0)
- The concept of alpha-synuclein as a prion-like protein: ten years after (2018) (0)
- Deficits in olfactory sensitivity in a mouse model of Parkinson’s disease revealed by plethysmography of odor-evoked sniffing (2020) (0)
- Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room (2019) (0)
- Microglia affect (cid:11) -synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease (2020) (0)
- Pretreatment with MK-801 or the lazaroid U-83836E does not enhance striatal graft survival. (2000) (0)
- Increased levels of circulating neurotoxic metabolites in patients with mild Covid19 (2022) (0)
- Does A "Prion-Like" Mechanism Contribute to the Spreading of Neuropathology in Parkinson's Disease? (2010) (0)
- This is NOT the End for Immunotherapy in Parkinson's Disease - A Perspective from Early Drug Development Scientists. (2022) (0)
- Faculty Opinions recommendation of A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. (2010) (0)
- Adult stem cell therapy – an option for the brain? (2005) (0)
- Behavior After Brain Infarction in Rats (2005) (0)
- Transplantation of NNCI cells after experimental stroke (2009) (0)
- Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein (2017) (0)
- Nigral and Striatal Grafts to the Lesioned Neostriatum: Models of Graft Function (1989) (0)
- Into Mechanisms Causing Neuronal Dysfunction and Death. It Diagnosis and Management of Peripheral Nerve Disorders Edited (0)
- Special Issue: "The immune System in Parkinson's Disease". Linking Immune Activation and Parkinson's Disease. (2022) (0)
- Faculty Opinions recommendation of Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death. (2011) (0)
- Alternative cell sources for transplantation in experimental Parkinson’s disease. (2003) (0)
- Viviane Labrie in Memoriam: Recollections of a Star Who Left Us Far Too Early. (2021) (0)
- Fulton symposium lecture: The battle to beat Parkinson’s disease (2019) (0)
- IV.4 Stem cells, viral vectors and other neurorestorative treatments (2006) (0)
- Evidence of seeding capacity of α-synuclein assemblies in infantile Krabbe disease. (2022) (0)
- Editorial Board (2008) (0)
- Cell Transplantation in PD 31 31 2 Developing Novel Cell Sources for Transplantation in Parkinson ’ s Disease (2018) (0)
- VPS41-mediated neuroprotection in a Caenorhabditis elegans model of Parkinson’s disease (2012) (0)
- [Not everything worked perfectly in Thailand]. (2005) (0)
- Cell Replacement Therapy: Parkinson’s Disease (2009) (0)
- Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease (2019) (0)
- Editorial Board (2017) (0)
- Ex vivo transfer of the gene for human Cu/Zn superoxide dismutase into embryonic dopamine neurons using an adenovirus vector (1997) (0)
- α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb (2019) (0)
- Acknowledgements to Reviewers (2004) (0)
- FETAL BRAIN GRAFTS AND PARKINSONS-DISEASE - RESPONSE (1990) (0)
- Twelfth Annual Conference of the American Society for Neural Transplantation & Repair Clearwater Beach, Florida, April 28–May 1, 2005 (2005) (0)
- Gene Therapy in Animal Models of Neurological Disorders (1992) (0)
- Combining neuroprotective treatment of embryonic nigral donor tissue with mild hypothermia of the graft recipient. (2005) (0)
- Developing Novel Cell Sources for Transplantation in Parkinson’s Disease (2006) (0)
- Acknowledgement to Reviewers (2006) (0)
- Membrane Interaction of α-Synuclein in Different Aggregation States (2012) (0)
- Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy (2022) (0)
- Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson’s disease (2022) (0)
- O.105 Is alpha-synuclein pathology propagated from one neuron to another in Parkinson's disease? (2009) (0)
- BRAIN DAMAGE, BRAIN REPAIR (2002) (0)
- Accumulating Evidence Suggests that Parkinson’s Disease Is a Prion-Like Disorder (2013) (0)
- Exosomes -Synuclein Aggregation by α Acceleration of (2014) (0)
- Developing Human Embryonic Stem Cells for Grafting in Parkinson's Disease (2005) (0)
- Is there a future for neural grafting? (2001) (0)
- Alterations in odor hedonics in the Tg6799 Alzheimer’s disease mouse model and the influence of sex (2020) (0)
- Expression of platelet-derived growth factor in and around intrastriatal embryonic mesencephalic grafts. (1993) (0)
- Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration (2018) (0)
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What Schools Are Affiliated With Patrik Brundin?
Patrik Brundin is affiliated with the following schools:
