Patrizia Casaccia

Patrizia Casaccia's AcademicInfluence.com Rankings

Patrizia Casaccia

Biology

#14884

World Rank

#18753

Historical Rank

Neuroscience

#2707

World Rank

#2778

Historical Rank

biology Degrees

Download Badge

Biology

Why Is Patrizia Casaccia Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Patrizia Casaccia is an Italian neuroscientist who is the Director of the Neuroscience Initiative of the Advanced Science Research Center at the City University of New York , as well as a Professor of Neuroscience, Genetics & Genomics, and Neurology at the Icahn School of Medicine at Mount Sinai. Casaccia is a pioneer in the study of myelin. Her research focuses on understanding the neurobiological and neuroimmune mechanisms of multiple sclerosis and to translate findings into treatments. Casaccia co-founded the Center for Glial Biology at Mount Sinai and CUNY and is one of the Directors of the center.

(See a Problem?)

Patrizia Casaccia's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models (2017) (593)
Impaired adult myelination in the prefrontal cortex of socially isolated mice (2012) (555)
Brain Cell Type Specific Gene Expression and Co-expression Network Architectures (2018) (252)
Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains (2013) (221)
Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior (2016) (207)
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease (2016) (204)
HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage (2009) (194)
Maternal Cannabis Use Alters Ventral Striatal Dopamine D2 Gene Regulation in the Offspring (2011) (188)
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions (2017) (175)
Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice (2016) (160)
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action (2015) (147)
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases (2014) (140)
Sulphate polyanions prolong the incubation period of scrapie-infected hamsters. (1992) (138)
Epigenetic regulation of oligodendrocyte identity (2010) (134)
Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment (2013) (123)
HDAC inhibitors and neurodegeneration: at the edge between protection and damage. (2010) (121)
Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions (2011) (118)
Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics. (2014) (115)
Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination (2010) (107)
Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression. (2014) (104)
Identification of a Gene Regulatory Network Necessary for the Initiation of Oligodendrocyte Differentiation (2011) (93)
Chromatin Landscape Defined by Repressive Histone Methylation during Oligodendrocyte Differentiation (2015) (92)
Two-tier transcriptional control of oligodendrocyte differentiation (2009) (88)
Differential Modulation of the Oligodendrocyte Transcriptome by Sonic Hedgehog and Bone Morphogenetic Protein 4 via Opposing Effects on Histone Acetylation (2012) (83)
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease (2017) (77)
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. (2016) (75)
Primary brain tumors, neural stem cell, and brain tumor cancer cells: Where is the link? (2010) (66)
Gene expression abnormalities and oligodendrocyte deficits in the internal capsule in schizophrenia (2010) (66)
Axonal damage in multiple sclerosis. (2011) (66)
Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice (2019) (63)
E2F1 Coregulates Cell Cycle Genes and Chromatin Components during the Transition of Oligodendrocyte Progenitors from Proliferation to Differentiation (2014) (62)
Disease-modifying therapies alter gut microbial composition in MS (2018) (59)
Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination (2015) (59)
Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia (2013) (59)
PRMT5-mediated regulation of developmental myelination (2018) (57)
Mechanostimulation Promotes Nuclear and Epigenetic Changes in Oligodendrocytes (2016) (56)
Cell‐context specific role of the E2F/Rb pathway in development and disease (2009) (55)
Amphotericin B: a novel class of antiscrapie drugs. (1989) (52)
Selective inhibitors of nuclear export avert progression in preclinical models of inflammatory demyelination (2015) (51)
Wellness and multiple sclerosis: The National MS Society establishes a Wellness Research Working Group and research priorities (2017) (51)
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination (2019) (51)
Epigenetic control of oligodendrocyte development: adding new players to old keepers (2016) (50)
Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression (2015) (48)
Widespread transcriptional alternations in oligodendrocytes in the adult mouse brain following chronic stress (2018) (46)
Bromodomains: Translating the words of lysine acetylation into myelin injury and repair (2016) (43)
Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria (2018) (42)
c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation (2014) (39)
Roles of p53 and p27 Kip1 in the regulation of neurogenesis in the murine adult subventricular zone (2011) (38)
Shaping the oligodendrocyte identity by epigenetic control (2010) (37)
Efficient Remyelination Requires DNA Methylation (2017) (37)
Progressive multiple sclerosis and gray matter pathology: an MRI perspective. (2011) (34)
Levels of infectivity in the blood throughout the incubation period of hamsters peripherally injected with scrapie (2005) (34)
Interplay between transcriptional control and chromatin regulation in the oligodendrocyte lineage (2015) (31)
Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (2014) (31)
Epigenetic Modifiers Are Necessary but Not Sufficient for Reprogramming Non-Myelinating Cells into Myelin Gene-Expressing Cells (2010) (31)
A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis. (2019) (29)
Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination (2010) (29)
The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination (2016) (29)
The Microbiome–Gut–Behavior Axis: Crosstalk Between the Gut Microbiome and Oligodendrocytes Modulates Behavioral Responses (2017) (27)
Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course (2019) (27)
Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP (2020) (25)
Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes (2016) (24)
Household paired design reduces variance and increases power in multi-city gut microbiome study in multiple sclerosis (2020) (22)
Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation (2017) (22)
Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1. (2018) (21)
TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice (2021) (21)
Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma. (2021) (20)
Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis (2019) (19)
Epigenetics in NG2 glia cells (2016) (19)
DNA methylation in oligodendroglial cells during developmental myelination and in disease (2017) (19)
Epigenetic modifications in brain and immune cells of multiple sclerosis patients (2018) (18)
Multiple sclerosis patient-derived CSF induces transcriptional changes in proliferating oligodendrocyte progenitors (2015) (17)
Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation (2018) (15)
Mechano‐modulation of nuclear events regulating oligodendrocyte progenitor gene expression (2019) (14)
Gut dysbiosis is a feature of MS and it is characterized by bacteria able to regulate lymphocyte differentiation in vitro (2016) (14)
HDAC1 in axonal degeneration (2010) (11)
Oligodendrocyte progenitors as environmental biosensors. (2020) (11)
Measurement of the concentration of amphotericin B in brain tissue of scrapie-infected hamsters with a simple and sensitive method (1991) (10)
EPIGENETIC MECHANISMS IN MULTIPLE SCLEROSIS. (2014) (10)
Anti-TANKyrase weapons promote myelination (2011) (9)
White Matter Plasticity in Anxiety: Disruption of Neural Network Synchronization During Threat-Safety Discrimination (2020) (9)
Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients (2017) (9)
Beyond the neuron: Role of non-neuronal cells in stress disorders (2022) (9)
The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming (2019) (8)
TET1-mediated DNA hydroxy-methylation regulates adult remyelination (2019) (8)
Defining the chromatin landscape in demyelinating disorders (2010) (8)
Combinatorial actions of Tgf&bgr; and Activin ligands promote oligodendrocyte development and CNS myelination (2014) (8)
Gut-brain communication in demyelinating disorders (2020) (7)
A retrospective study of Creutzfeldt-Jakob disease in Italy (1972–1986) (1988) (7)
An integrated approach to design novel therapeutic interventions for demyelinating disorders (2012) (6)
Promoting return of function in multiple sclerosis: An integrated approach. (2013) (6)
Retrospective unbiased plasma lipidomic of progressive multiple sclerosis patients-identifies lipids discriminating those with faster clinical deterioration (2020) (5)
Does the gut microbiota contribute to the oligodendrocyte progenitor niche? (2020) (4)
The MS Microbiome Consortium (MSMC): an academic multi-disciplinary collaborative effort to elucidate the role of the gut microbiota in MS (P2.205) (2015) (4)
Effect of oral versus injectable disease-modifying therapies on the epigenome-wide DNA methylation and gut microbiota in multiple sclerosis patients (2016) (4)
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease (2016) (4)
N‐myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination (2021) (4)
Possible Implications of the Cellular Component of the Immune System in the Pathogenesis of Unconventional Slow Virus Infections (1990) (4)
Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation (2020) (4)
Microbiota-driven transcriptional changes in prefrontal cortex override genetic 1 differences in social behavior 2 3 4 (2016) (3)
PRMT5 Interacting Partners and Substrates in Oligodendrocyte Lineage Cells (2022) (3)
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation (2022) (3)
Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging. (2020) (3)
The influence of microbiota on the adaptive immune response in MS (2015) (3)
ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve (2022) (2)
Correction: Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (doi:10.1242/dev.106492) (2018) (2)
The MS-Associated Gut Microbiome (2017) (1)
Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures (2018) (1)
Correction: Zhao et al., “Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination” (2017) (1)
PADI2-mediated citrullination is required for efficient oligodendrocyte differentiation and myelination (2018) (1)
Author response: Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice (2019) (1)
Erratum: Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics (Brain (2014) 137 (2271-2286) DOI: 10.1093/brain/awu139) (2015) (1)
The Microbiome–Gut–Behavior Axis: Crosstalk Between the Gut Microbiome and Oligodendrocytes Modulates Behavioral Responses (2017) (1)
Neurobiology of Disease Conserved Chromosome 2 q 31 Conformations Are Associated with Transcriptional Regulation of GAD 1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia (2017) (1)
Foreword (2020) (1)
The epigenetic landscape of oligodendrocyte lineage cells (2023) (0)
Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures (2021) (0)
Implication of DNA methylation changes at chromosome 1q21.1 in the brain pathology of Primary Progressive Multiple Sclerosis (2022) (0)
Emerging concepts in neuroscience research: 2019 highlights (2020) (0)
Introduction to the special issue on myelin plasticity in the central nervous system (2018) (0)
The Role of Protein Deimination in Epigenetics (2014) (0)
Title : Multiple sclerosis-associated changes in the composition and immune functions of 1 spore-forming bacteria 2 3 Running title : Spore-forming bacteria in multiple sclerosis 4 5 (2018) (0)
Early life events effect on myelin gene expression (2013) (0)
CSF from MS Patients Induces Mitochondrial Dysfunction in Unmyelinated Neuronal Cultures (P05.179) (2013) (0)
Measurement oftheConcentration ofAmphotericin B in BrainTissue ofScrapie-Infected Hamsters with aSimple andSensitive Method (1991) (0)
Abstract 1459: Emergent properties of heterochromatin component condensates (2023) (0)
SINE Compounds Demonstrate Efficacy in a Preclinical Model of Multiple Sclerosis and an In Vitro Screening of Viral Agents of Coinfection (P1.405) (2017) (0)
PRMT5-mediated regulation of developmental myelination (2018) (0)
Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation (2020) (0)
Link between vascular risk factors and grey matter cortical thickness in early MS and the moderating influence of sex (S24.006) (2018) (0)
OLIGODENDROCYTE-ENRICHED GENE NETWORKS REVEAL NOVEL PATHWAYS AND KEY TARGETS IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE (2016) (0)
ACCELERATING MEDICINES PARTNERSHIP: CO-EXPRESSION NETWORKS (2016) (0)
Editorial Board (2010) (0)
Xenogeneic assessment of mitochondrial bioenergetic impairment induced by CSF from MS patients (P2.369) (2017) (0)
Cutting Edge Developments in MS Research (2017) (0)
Title Role of Tet 1 and 5-hydroxymethylcytosine in cocaine action Permalink (2015) (0)
Prenatal Exposure to a Climate-Related Disaster Results in Changes of the Placental Transcriptome and Infant Temperament (2022) (0)
Immunosurveillance of CCR6+ T-cells predicts treatment response to dimethyl-fumarate: implications for personalized treatment strategies in multiple sclerosis (2020) (0)
Effect of dimethyl fumarate and glatiramer acetate on the immunological profiles and gut microbiota in Multiple Sclerosis patients (P6.379) (2017) (0)
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease (2017) (0)
Fumaric acid esters hypermethylate the miR21 locus and prevent the formation of CCR6+ CD4 T cells in multiple sclerosis. (2018) (0)

This paper list is powered by the following services:

Other Resources About Patrizia Casaccia

en.wikipedia.org

What Schools Are Affiliated With Patrizia Casaccia?

Patrizia Casaccia is affiliated with the following schools: