Paul Breslin
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American biologist
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Paul Breslinbiology Degrees
Biology
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Genetics
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Molecular Biology
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Biology
Paul Breslin's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is Paul Breslin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Paul Breslin is a geneticist and biologist. He is most notable for his work in taste perception and oral irritation, in humans as well as in Drosophila melanogaster, the common fruit fly. He is a member of the faculty at the Monell Chemical Senses Center and acts as director of the Science Apprenticeship Program. He is a professor in the Department of Nutritional Sciences at Rutgers, the State University of New Jersey. Breslin and two colleaguesdiscovered that Oleocanthal, a compound found in extra-virgin olive oil kills a variety of human cancer cells without harming healthy cells.
Paul Breslin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil (2005) (769)
- The Molecular Basis of Individual Differences in Phenylthiocarbamide and Propylthiouracil Bitterness Perception (2005) (657)
- An overview of binary taste–taste interactions (2003) (437)
- The merging of the senses: integration of subthreshold taste and smell (2000) (354)
- An Evolutionary Perspective on Food and Human Taste (2013) (309)
- Salt enhances flavour by suppressing bitterness (1997) (217)
- Suppression of bitterness by sodium: variation among bitter taste stimuli. (1995) (217)
- Individual Differences in AMY1 Gene Copy Number, Salivary α-Amylase Levels, and the Perception of Oral Starch (2010) (208)
- Gender-specific induction of enhanced sensitivity to odors (2002) (203)
- Psychophysical evidence that oral astringency is a tactile sensation (1993) (200)
- Variability in a taste-receptor gene determines whether we taste toxins in food (2006) (183)
- Identification of human gustatory cortex by activation likelihood estimation (2011) (174)
- Genetics of Human Taste Perception (2004) (162)
- Mammalian taste perception (2008) (160)
- High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults. (2012) (158)
- Interactions among salty, sour and bitter compounds (1996) (151)
- Taste reactivity as a dependent measure of the rapid formation of conditioned taste aversion: a tool for the neural analysis of taste-visceral associations. (1988) (147)
- Covariation in individuals’ sensitivities to bitter compounds: Evidence supporting multiple receptor/transduction mechanisms (2001) (137)
- Perceptual variation in umami taste and polymorphisms in TAS1R taste receptor genes. (2009) (131)
- Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. (2009) (131)
- The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12 (2010) (126)
- Unusual Pungency from Extra-Virgin Olive Oil Is Attributable to Restricted Spatial Expression of the Receptor of Oleocanthal (2011) (121)
- A quantitative comparison of taste reactivity behaviors to sucrose before and after lithium chloride pairings: a unidimensional account of palatability. (1992) (114)
- Relationship of papillae number to bitter intensity of quinine and PROP within and between individuals (2001) (113)
- Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin (2011) (112)
- A TAS1R receptor-based explanation of sweet ‘water-taste’ (2006) (105)
- Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine. (2006) (103)
- Salivary Amylase: Digestion and Metabolic Syndrome (2016) (100)
- Twin study of the heritability of recognition thresholds for sour and salty taste. (2007) (98)
- Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. (2012) (92)
- Human taste: peripheral anatomy, taste transduction, and coding. (2006) (90)
- Synthesis and assignment of absolute configuration of (-)-oleocanthal: a potent, naturally occurring non-steroidal anti-inflammatory and anti-oxidant agent derived from extra virgin olive oils. (2005) (79)
- Modifying the Bitterness of Selected Oral Pharmaceuticals with Cation and Anion Series of Salts (2002) (77)
- Monogeusia for fructose, glucose, sucrose, and maltose (1996) (72)
- Gustation assessment using the NIH Toolbox (2013) (71)
- Suppression of Bitterness Using Sodium Salts (2001) (65)
- (-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization (2015) (63)
- Cross-adaptation and bitterness inhibition of L-tryptophan, L-phenylalanine and urea: further support for shared peripheral physiology. (2002) (62)
- Drosophila melanogaster prefers compounds perceived sweet by humans. (2008) (59)
- Flavor Interactions at the Sensory Level (2007) (59)
- Lick rate analysis of sodium taste-state combinations. (1993) (57)
- Chorda tympani section decreases the cation specificity of depletion-induced sodium appetite in rats. (1993) (57)
- A Common Genetic Influence on Human Intensity Ratings of Sugars and High-Potency Sweeteners (2015) (57)
- Sweet taste and menthol increase cough reflex thresholds. (2012) (57)
- Oral Perceptions of Fat and Taste Stimuli Are Modulated by Affect and Mood Induction (2013) (54)
- Sensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oils. (2009) (53)
- Conditioned reversal of reactions to normally avoided tastes (1990) (51)
- The influence of sodium salts on binary mixtures of bitter-tasting compounds. (2004) (51)
- A psychophysical investigation of binary bitter-compound interactions. (2003) (50)
- Oral zinc sulfate solutions inhibit sweet taste perception. (2004) (48)
- Bitter taste induces nausea (2011) (47)
- Human gustation and flavour (2001) (47)
- Single sweetness signal (1994) (43)
- Bitterness Suppression with Zinc Sulfate and Na-Cyclamate: A Model of Combined Peripheral and Central Neural Approaches to Flavor Modification (2005) (42)
- The liaison of sweet and savory. (2006) (42)
- Reduction of saltiness and bitterness after a chlorhexidine rinse. (2001) (41)
- New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances. (2019) (41)
- Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa. (2014) (39)
- Are human taste thresholds similar on the right and left sides of the tongue? (2001) (34)
- Ibuprofen as a chemesthetic stimulus: evidence of a novel mechanism of throat irritation. (2001) (34)
- Individual differences in sour and salt sensitivity: detection and quality recognition thresholds for citric acid and sodium chloride. (2013) (30)
- Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization (2018) (30)
- Sodium specificity of salt appetite in Fischer-344 and Wistar rats is impaired by chorda tympani nerve transection. (1995) (28)
- Psychophysics of taste lateralization on anterior tongue (2000) (27)
- Opponency of astringent and fat sensations (2012) (27)
- Immune cells of the human peripheral taste system: Dominant dendritic cells and CD4 T cells (2009) (27)
- Saccharin increases the effectiveness of glucose in stimulating ingestion in rats but has little effect on negative feedback (1996) (26)
- Characterization of human fungiform papillae cells in culture. (2011) (26)
- Flavor processing: perceptual and cognitive factors in multi-modal integration. (2005) (26)
- Selective removal of a target stimulus localized by taste in humans. (2000) (25)
- Oral Cooling and Carbonation Increase the Perception of Drinking and Thirst Quenching in Thirsty Adults (2016) (24)
- The Genetics of Bitterness and Pungency Detection and Its Impact on Phytonutrient Evaluation (2009) (24)
- Effect of Taste Sensation on Cough Reflex Sensitivity (2014) (20)
- Gender-specific olfactory sensitization: hormonal and cognitive influences. (2005) (19)
- Is the Association Between Sweet and Bitter Perception due to Genetic Variation? (2016) (16)
- Psychophysical isolation of the modality responsible for detecting multimodal stimuli: a chemosensory example. (2005) (16)
- Relationships among taste qualities assessed with response-context effects. (2011) (15)
- Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste (2018) (14)
- Lipid-Lowering Pharmaceutical Clofibrate Inhibits Human Sweet Taste (2017) (14)
- Clofibrate inhibits the umami-savory taste of glutamate (2017) (14)
- A behavioral analysis of the ingestion of glucose, maltose and maltooligosaccharide by rats (2000) (12)
- (-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells (2019) (12)
- β-carotene-producing bacteria residing in the intestine provide vitamin A to mouse tissues in vivo. (2014) (11)
- Sweet Taste Perception is Associated with Body Mass Index at the Phenotypic and Genotypic Level (2016) (10)
- Bitter Taste Receptors (T2Rs) are Sentinels that Coordinate Metabolic and Immunological Defense Responses. (2021) (9)
- The evolution of sour taste (2022) (9)
- Associations between brain structure and perceived intensity of sweet and bitter tastes (2019) (8)
- The T cells in peripheral taste tissue of healthy human adults: predominant memory T cells and Th-1 cells. (2010) (7)
- Multi-modal Sensory Integration: Evaluating Foods and Mates (2008) (6)
- Evidence that human oral glucose detection involves a sweet taste pathway and a glucose transporter pathway (2021) (6)
- Taste after-images: the science of “water-tastes” (2007) (6)
- Clustering Bitter Compounds via Individual Sensitivity Differences: Evidence Supporting Multiple Receptor-Transduction Mechanisms (2002) (6)
- Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions (2021) (5)
- Studies of Human Twins Reveal Genetic Variation That Affects Dietary Fat Perception (2020) (5)
- hTAS 2 R 38 RECEPTOR GENOTYPES PREDICT SENSITIVITY TO BITTERNESS OF THIOUREA COMPOUNDS IN SOLUTION AND IN SELECTED VEGETABLES (2010) (4)
- Stability of the trastuzumab biosimilar ABP 980 compared to reference product after intravenous bag preparation, transport and storage at various temperatures, concentrations and stress conditions (2020) (4)
- Oral Signals of Short and Long Chain Fatty Acids: Parallel Taste Pathways to Identify Microbes and Triglycerides. (2021) (4)
- Chemical Senses in Feeding, Belonging, and Surviving (2019) (3)
- Limited Evidence for Adaptive Evolution and Functional Effect of Allelic Variation at rs702424 in the Promoter of the TAS2R16 Bitter Taste Receptor Gene in Africa (2014) (3)
- Sodium, but not potassium, blocks bitterness in simple model chicken broths (2019) (3)
- Why Naturally Healthy Berries May Be Seen as Unpleasant and Non-appetitive? (2008) (3)
- The Sense of Taste Encompasses Two Roles: Conscious Taste Perception and Subconscious Metabolic Responses (2019) (3)
- Oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells (2019) (3)
- A microstructural analysis of NaCl drinking bouts in rats (1992) (2)
- Inhibition of Bitter Taste from Oral Tenofovir Alafenamide (2021) (2)
- Synthesis and Assignment of Absolute Configuration of (-)-Oleocanthal: A Potent, Naturally Occurring Non-Steroidal Antiinflammatory and Antioxidant Agent Derived from Extra Virgin Olive Oils. (2006) (2)
- Replication of linkage and association of PROP perception to chromosome 7 and suggestion of novel loci on chromosome 6 (2006) (1)
- Diagnostic exercise: paralysis in a Long-Evans rat. (1989) (1)
- A rticle Origin and Differential Selection of Allelic Variation at TAS 2 R 16 Associated with Salicin Bitter Taste Sensitivity in Africa (2017) (1)
- Anterior olfactory nucleus and piriform cortex feedback differentially modulate olfactory bulb output neurons (2018) (1)
- Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization (2018) (0)
- What Can Psychophysical Studies with Sweetness Inhibitors Teach Us about Taste (2008) (0)
- Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization (2020) (0)
- High Endocannabinoid Tone In LFABP -/- Mice Drives Fat Intake and Preference (2021) (0)
- The Effect of Dietary Fiber Enrichment on Taste Perception in Humans (2015) (0)
- GWAS of bitter taste perception in Australian adolescents (2016) (0)
- Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization (2020) (0)
- The MTHFR 677TT Variant is Associated with Impaired Acute Blood Pressure Response to Sodium Ingestion (2017) (0)
- Evolutionary Perspectives on Food and Human Taste (2017) (0)
- Introductory Letter to Special Issue (2008) (0)
- The Bidirectional Modulatory Effects of Ribonucleotides on Glutamate Detection Thresholds (2021) (0)
- Is the Association between Sweet and Bitter Perception due to Genetics (2016) (0)
- Individual Differences in Adaptation to Sweet Taste (2021) (0)
- The Taste of Fermentation: Propionic Acid Is Judged More Pleasant Than Other Short Chain Fatty Acids (2021) (0)
- Nutrient-Nutrient Interactions b-Carotene – Producing Bacteria Residing in the Intestine Provide Vitamin A to Mouse Tissues In Vivo 1 – 3 (2014) (0)
- Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste (2018) (0)
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